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Cemented dual-mobility total hip arthroplasty cups in a custom-made acetabulum: a clinical and radiological evaluation. 骨水泥双活动全髋关节置换术杯在定制髋臼:临床和放射学评价。
IF 2.3 Q2 ORTHOPEDICS Pub Date : 2025-01-01 Epub Date: 2025-08-26 DOI: 10.1051/sicotj/2025049
Nicolas Blum, Guillaume Mesnard, Cécile Batailler, Sébastien Lustig

Background: Acetabular reconstruction during revision total hip arthroplasty (THA) with major bone loss is a complex surgical challenge. The combination of custom-made (CM) acetabular components with cemented dual mobility (DM) cups may improve postoperative outcomes in this context. This study aims to assess the clinical, functional, and radiological results of this surgical approach.

Methods: We conducted a retrospective, single-center observational study including 16 patients (mean age 70 years) who underwent revision THA between May 2016 and December 2024 using a cemented DM cup in a CM acetabular component. All patients presented with Paprosky 3A or 3B defects, and 38% had a history of periprosthetic joint infection (PJI). Functional outcomes were measured using the Oxford Hip Score (OHS) and modified Harris Hip Score (mHHS) pre- and postoperatively. Radiographic assessment included measurement of the center of rotation (COR) deviation in both axes, as well as acetabular inclination and anteversion on postoperative CT scans. Implant survival was analyzed using Kaplan-Meier methodology.

Results: At a mean follow-up of 16.2 months, overall implant survival was 75%, increasing to 93.8% when excluding isolated DM cup revisions. No postoperative infections were observed. OHS improved from 14.1 to 27.6 and mHHS from 27.4 to 52.7 (p < 0.001 for both). A significant negative correlation was observed between vertical (y-axis) COR deviation and functional scores (p < 0.01), highlighting the importance of restoring vertical COR. Mean inclination and anteversion were 41.2° and 29°, respectively, generally within target alignment zones.

Discussion: The combination of cemented DM cups with CM acetabular components appears to be an effective technique in complex revision THA. Functional recovery and implant survivorship are consistent with the existing literature, and the absence of infection despite prior PJI history suggests benefit from a multidisciplinary approach. Restoration of vertical COR is a predictor of functional outcomes.

背景:髋臼重建翻修全髋关节置换术(THA)期间,主要的骨质流失是一个复杂的手术挑战。在这种情况下,定制(CM)髋臼假体与胶结双活动杯(DM)的结合可以改善术后预后。本研究旨在评估该手术入路的临床、功能和放射学结果。方法:我们进行了一项回顾性的单中心观察研究,包括16例患者(平均年龄70岁),他们在2016年5月至2024年12月期间使用DM杯在CM髋臼组件中进行了翻修THA。所有患者均存在帕普罗斯基3A或3B缺陷,38%患者有假体周围关节感染(PJI)史。术前和术后使用牛津髋关节评分(OHS)和改良Harris髋关节评分(mHHS)测量功能结果。影像学评估包括测量两轴的旋转中心(COR)偏差,以及术后CT扫描的髋臼倾斜和前倾。采用Kaplan-Meier方法分析种植体存活。结果:在平均16.2个月的随访中,种植体的总存活率为75%,如果排除孤立的DM杯修复,则增加到93.8%。无术后感染。OHS从14.1提高到27.6,mHHS从27.4提高到52.7 (p < 0.001)。垂直(y轴)COR偏差与功能评分呈显著负相关(p < 0.01),突出了恢复垂直COR的重要性。平均倾斜度和前倾度分别为41.2°和29°,一般在目标对齐区域内。讨论:骨水泥DM假杯与CM髋臼假体的结合似乎是复杂翻修THA的有效技术。功能恢复和种植体存活与现有文献一致,尽管有PJI病史,但没有感染,这表明多学科方法有益。垂直COR的恢复是功能预后的预测指标。
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引用次数: 0
Transforming joint replacement with open robotics: A call for change! 用开放机器人改造关节置换:呼吁变革!
IF 2.3 Q2 ORTHOPEDICS Pub Date : 2025-01-01 Epub Date: 2025-12-10 DOI: 10.1051/sicotj/2025059
Vaibhav Bagaria, Raju Vaishya
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引用次数: 0
Outcome of surgical treatment for metastatic bone disease of the distal femur: Observational single-center study of 47 patients. 股骨远端转移性骨病手术治疗的结果:47例患者的观察性单中心研究
IF 2.3 Q2 ORTHOPEDICS Pub Date : 2025-01-01 Epub Date: 2026-01-06 DOI: 10.1051/sicotj/2025062
Adam Mellgren, Panagiotis Tsagkozis

Introduction: There is a paucity of data regarding the surgical treatment of distal femoral metastatic lesions. In this retrospective study, we aim to describe the outcome of surgery in this location and further analyze the findings based on the type of surgical reconstruction.

Methods: 47 patients (48 fractures) who underwent surgery due to pathological fractures of the distal third of the femur, between 2000 and 2024, were included in the analysis. There were 29 prostheses and 19 osteosyntheses (10 plates, 9 nails). Local complications, implant revision rate, functional outcome regarding pain and ambulatory capacity, and overall survival were analyzed depending on the type of surgical treatment.

Results: The complication pattern was different among implants used, with severe infections seen in prostheses (3/29 implants) and tumor recurrence in osteosynthesis (2/19 implants). In cases of osteosynthesis, failures resulting in revision surgery were documented only in cases of plate reconstruction (none when nails were used), resulting in a marginally higher revision rate (p = 0.14). Surgical treatment resulted in the restoration of the ambulatory capacity in 85% of patients, and pain levels were minor or moderate in 93%, without any significant difference between the surgical methods. Prostheses were used in patients with better overall survival (p = 0.015).

Discussion: The patterns of local complications and their management differed between the different reconstruction techniques. Plate osteosynthesis had the highest risk for re-operation. The overall postoperative result was satisfactory, and functional outcomes were generally comparable. Patients with a good prognosis should be considered for reconstruction with a prosthesis when the bone quality does not allow nail osteosynthesis.

Level of evidence: IV, retrospective study.

介绍:关于股骨远端转移性病变的手术治疗的数据缺乏。在这项回顾性研究中,我们旨在描述该部位的手术结果,并根据手术重建的类型进一步分析结果。方法:回顾性分析2000年至2024年间因股骨远端病理性骨折行手术治疗的47例患者(48例骨折)。假体29例,植骨19例(钢板10例,钉9例)。根据手术治疗的类型,分析局部并发症、种植体翻修率、疼痛和行动能力的功能结局以及总生存率。结果:不同种植体的并发症类型不同,3/29种植体出现严重感染,2/19种植体出现肿瘤复发。在植骨手术中,只有钢板重建导致翻修手术失败的病例被记录下来(当使用钉子时没有),导致翻修率略高(p = 0.14)。手术治疗使85%的患者恢复了行动能力,93%的患者疼痛程度为轻微或中度,两种手术方式之间无显著差异。总生存率较高的患者使用假体(p = 0.015)。讨论:不同重建技术的局部并发症类型及其处理方法不同。钢板接骨术再次手术的风险最高。术后总体结果令人满意,功能结果一般可比较。预后良好的患者,当骨质不允许指甲成骨时,应考虑用假体重建。证据等级:IV级,回顾性研究。
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引用次数: 0
Management of a rare case of anterior cruciate ligament reconstruction in a Paralympic athlete with a transtibial amputation - a case report. 对一名经胫骨截肢的残奥会运动员进行前十字韧带重建的罕见病例处理--病例报告。
IF 1.8 Q2 ORTHOPEDICS Pub Date : 2025-01-01 Epub Date: 2025-04-08 DOI: 10.1051/sicotj/2025022
Alexandre Le Guen, Thibaut Lucena, Eric Laboute, Etienne Cavaignac

Advances in technology, prosthetic components and rehabilitation techniques have improved the quality of life for amputees. Wearing a prosthesis enabled them to participate in sports at a high level. Participating in competitive sports puts them at risk of joint injury. This case describes a disabled professional paralympic athlete with a transtibial amputation who has torn his anterior cruciate ligament (ACL). This patient underwent anterior cruciate ligament reconstruction one year before the Paris 2024 Paralympic Games. Surgery had to be adapted in terms of the patient's operative position, choice of graft and incisions to limit conflict with the prosthesis. Anterior cruciate ligament reconstruction with an ipsilateral quadriceps tendon graft enabled the patient to return to competition and place 4th in his category at the Paris 2024 Paralympic Games. This is the first case of ACL reconstruction in a transtibial amputee reported in the literature. It highlights a rare and difficult surgical procedure that can yield good results.

技术、假肢部件和康复技术的进步提高了截肢者的生活质量。佩戴假肢使他们能够参加高水平的体育运动。参加竞技运动使他们有关节受伤的危险。这个案例描述了一个残疾的职业残奥会运动员,他的前交叉韧带(ACL)撕裂,经胫骨截肢。该患者在2024年巴黎残奥会前一年接受了前十字韧带重建。手术必须根据患者的手术位置、移植物的选择和切口进行调整,以限制与假体的冲突。通过同侧股四头肌肌腱移植重建前交叉韧带,使患者能够重返比赛,并在2024年巴黎残奥会上获得他所在类别的第四名。这是文献中报道的第一例跨胫截肢者ACL重建。它强调了一种罕见而困难的外科手术,可以产生良好的效果。
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引用次数: 0
Retrograde femoral nailing for deformity correction and fracture treatment in osteogenesis imperfecta: clinical and radiological assessment of a novel technique. 逆行股骨内钉治疗成骨不全畸形和骨折:一种新技术的临床和放射学评估。
IF 1.8 Q2 ORTHOPEDICS Pub Date : 2025-01-01 Epub Date: 2025-04-17 DOI: 10.1051/sicotj/2025020
Samuel Georges, Ibrahim Saliba, Georges Finidori, Edouard Haumont, Stephanie Pannier, Zagorka Pejin

Introduction: Intramedullary anterograde femoral nailing is a standard treatment for femoral deformity and fracture in osteogenesis imperfecta (OI). This study evaluates the clinical and radiological outcomes of a novel retrograde femoral nailing technique.

Methods: A retrospective analysis was performed on 31 patients with OI who underwent retrograde femoral nailing using Dubow-Bailey nails from 2004 to 2019. A total of 54 femurs were treated for femoral deformity or fracture by three senior surgeons, with a mean follow-up of 2.7 years. Clinical outcomes, including knee range of motion and pain, were assessed. Radiological outcomes included deformity angle (DA), neck shaft angle (NSA), mechanical lateral distal femoral angle (mLDFA), and nail positioning on AP and lateral X-rays. Potential complications, including hip osteonecrosis, distal femoral growth arrest, and infections, were also evaluated.

Results: The procedure showed favorable outcomes, with no postoperative knee motion limitations or persistent pain. The mean pre-operative DA on AP and lateral views was 29° and 40°, respectively, with no residual deformity after surgery. The mean NSA and mLDFA were 132° and 101° before surgery, compared to 143° and 89° post-operatively. Nail alignment was optimal in 81% of the femurs, with proper positioning in both the distal epiphysis and femoral neck. No cases of hip osteonecrosis, distal femoral growth arrest, or infection were reported. Hardware migration occurred in seven cases.

Conclusion: Retrograde femoral nailing is a safe and effective technique for managing femoral deformities and fractures in OI.

导读:顺行股骨髓内钉是治疗成骨不全症(OI)股骨畸形和骨折的标准方法。本研究评估了一种新型逆行股骨内钉技术的临床和放射学结果。方法:回顾性分析2004 - 2019年31例成骨不全患者行Dubow-Bailey逆行股内钉治疗的临床资料。共有54例股骨由3名资深外科医生治疗股骨畸形或骨折,平均随访2.7年。评估临床结果,包括膝关节活动度和疼痛程度。放射学结果包括畸形角(DA)、颈轴角(NSA)、机械外侧股骨远端角(mLDFA)以及AP和侧位x线上的钉位。潜在的并发症,包括髋关节骨坏死,股骨远端生长停止和感染,也进行了评估。结果:手术显示了良好的结果,没有术后膝关节运动限制或持续疼痛。术前正侧位和侧位平均DA分别为29°和40°,术后无畸形残留。术前平均NSA和mLDFA分别为132°和101°,术后平均NSA和mLDFA分别为143°和89°。81%的股骨的钉位是最佳的,在远端骨骺和股骨颈都有适当的定位。没有髋部骨坏死、股骨远端生长停止或感染的病例报道。硬件迁移发生在七个案例中。结论:逆行股骨内钉是治疗成骨不全患者股骨畸形和骨折的一种安全有效的技术。
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引用次数: 0
Superficial band of the quadriceps tendon harvested with a minimally invasive technique provides adequate graft dimensions: a cadaveric study. 采用微创技术收获的股四头肌肌腱浅层带提供了足够的移植物尺寸:尸体研究。
IF 1.8 Q2 ORTHOPEDICS Pub Date : 2025-01-01 Epub Date: 2025-07-16 DOI: 10.1051/sicotj/2025037
Napatpong Thamrongskulsiri, Varachaya Khwanjaipanich, Danaithep Limskul, Thanathep Tanpowpong, Somsak Kuptniratsaikul, Thun Itthipanichpong

Introduction: This study explored a minimally invasive technique for harvesting the superficial band of the quadriceps tendon. By using a conventional graft tendon stripper, the procedure aims to obtain the full length of tendon fibers necessary for anterior cruciate ligament (ACL) reconstruction. The study aimed to determine if this technique can produce grafts of sufficient length and diameter.

Methods: From September to October 2023, we conducted a study using full-body Thiel-embalmed cadavers over 18 years of age without pathology-related alterations in lower limb anatomy. The mid-diameter of the graft was measured at its midpoint, and the peripheral diameter was taken at the ends. The length of the triple-folded graft was measured from end to end. A digital vernier caliper measured the length and mid-diameter, and a graft sizer measured the peripheral diameter.

Results: Sixteen quadriceps tendon autografts were harvested from 16 knees of 8 cadavers (mean age: 64.7 ± 9.9 years). The minimally invasive harvesting technique yielded a mean graft length of 289.0 ± 10.3 mm before folding, a mean mid-diameter of 9.7 ± 0.7 mm, a mean peripheral diameter of 8.5 ± 0.4 mm, and a mean length of 93.1 ± 4.7 mm after triple folding. Gender-based comparisons showed no significant differences. Correlations between graft dimensions and height were not statistically significant.

Discussion: The findings of this study indicate that the minimally invasive harvesting of the superficial band of the quadriceps tendon resulted in adequate graft dimension. Gender-based comparisons revealed no statistically significant differences in these dimensions between males and females. Additionally, correlation analysis showed weak to moderate correlations between graft dimensions and height, none of which were statistically significant, indicating no meaningful relationship between height and graft dimensions.

简介:本研究探索了一种微创技术,用于收获股四头肌肌腱的浅层带。通过使用传统的移植物肌腱剥离器,该手术旨在获得重建前交叉韧带(ACL)所需的全长肌腱纤维。这项研究旨在确定这种技术是否能产生足够长度和直径的移植物。方法:我们于2023年9月至10月对18岁以上的全身thiel防腐尸体进行了研究,这些尸体没有病理相关的下肢解剖改变。在移植物的中点处测量移植物的中径,在末端处测量移植物的外周直径。从端到端测量三折移植物的长度。数字游标卡尺测量长度和中径,移植物大小仪测量外径。结果:8具尸体共16个膝关节,平均年龄64.7±9.9岁,共收获16根自体股四头肌肌腱。采用微创采收技术,折叠前平均移植物长度为289.0±10.3 mm,中径平均为9.7±0.7 mm,外径平均为8.5±0.4 mm,三次折叠后平均长度为93.1±4.7 mm。基于性别的比较显示无显著差异。嫁接尺寸与嫁接高度的相关性无统计学意义。讨论:本研究结果表明,微创摘取股四头肌肌腱浅层带可获得足够的移植物尺寸。基于性别的比较显示,男性和女性在这些方面没有统计学上的显著差异。此外,相关分析显示接枝尺寸与株高呈弱至中度相关,但均无统计学意义,说明株高与接枝尺寸之间无显著关系。
{"title":"Superficial band of the quadriceps tendon harvested with a minimally invasive technique provides adequate graft dimensions: a cadaveric study.","authors":"Napatpong Thamrongskulsiri, Varachaya Khwanjaipanich, Danaithep Limskul, Thanathep Tanpowpong, Somsak Kuptniratsaikul, Thun Itthipanichpong","doi":"10.1051/sicotj/2025037","DOIUrl":"10.1051/sicotj/2025037","url":null,"abstract":"<p><strong>Introduction: </strong>This study explored a minimally invasive technique for harvesting the superficial band of the quadriceps tendon. By using a conventional graft tendon stripper, the procedure aims to obtain the full length of tendon fibers necessary for anterior cruciate ligament (ACL) reconstruction. The study aimed to determine if this technique can produce grafts of sufficient length and diameter.</p><p><strong>Methods: </strong>From September to October 2023, we conducted a study using full-body Thiel-embalmed cadavers over 18 years of age without pathology-related alterations in lower limb anatomy. The mid-diameter of the graft was measured at its midpoint, and the peripheral diameter was taken at the ends. The length of the triple-folded graft was measured from end to end. A digital vernier caliper measured the length and mid-diameter, and a graft sizer measured the peripheral diameter.</p><p><strong>Results: </strong>Sixteen quadriceps tendon autografts were harvested from 16 knees of 8 cadavers (mean age: 64.7 ± 9.9 years). The minimally invasive harvesting technique yielded a mean graft length of 289.0 ± 10.3 mm before folding, a mean mid-diameter of 9.7 ± 0.7 mm, a mean peripheral diameter of 8.5 ± 0.4 mm, and a mean length of 93.1 ± 4.7 mm after triple folding. Gender-based comparisons showed no significant differences. Correlations between graft dimensions and height were not statistically significant.</p><p><strong>Discussion: </strong>The findings of this study indicate that the minimally invasive harvesting of the superficial band of the quadriceps tendon resulted in adequate graft dimension. Gender-based comparisons revealed no statistically significant differences in these dimensions between males and females. Additionally, correlation analysis showed weak to moderate correlations between graft dimensions and height, none of which were statistically significant, indicating no meaningful relationship between height and graft dimensions.</p>","PeriodicalId":46378,"journal":{"name":"SICOT-J","volume":"11 ","pages":"37"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12266663/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144650829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sensitivity of MRI reports for ligamentous injuries in high-grade knee dislocations: A single-center retrospective analysis of radiology reports and operative findings. MRI报告对高度膝关节脱位韧带损伤的敏感性:影像学报告和手术结果的单中心回顾性分析。
IF 2.3 Q2 ORTHOPEDICS Pub Date : 2025-01-01 Epub Date: 2025-08-04 DOI: 10.1051/sicotj/2025046
Magd Boutany, David Abdelnour, Alqasim Elnaggar, Eric Schweller, Rahul Vaidya

Introduction: Knee dislocations, particularly high-grade injuries such as Schenck class KDIV, are complex injuries often resulting from high-energy trauma. While magnetic resonance imaging (MRI) is widely used preoperatively to assess ligamentous damage, its diagnostic accuracy remains uncertain.

Methods: A retrospective review was conducted on 92 patients who underwent surgery for a knee dislocation at a Level I trauma center over 10 years. Patients who had a preoperative MRI report and intraoperative confirmation of a KDIV injury without a tibial plateau fracture were included, which left 31 patients. MRI sensitivity was determined by comparing radiology reports to operative findings with fluoroscopic examination under anesthesia (EUA) for injuries to the anterior cruciate ligament (ACL), posterior cruciate ligament (PCL), medial collateral ligament (MCL), lateral collateral ligament (LCL), and posterolateral corner (PLC). Postoperative follow-up documents were reviewed for functional outcomes. A one-way analysis of variance (ANOVA) was performed to evaluate differences in sensitivity across ligament types, followed by a Tukey post hoc test for pairwise comparisons. Mean flexion ROM at final follow-up (≥6 months) was compared between the accurate and inaccurate MRI cohorts using an independent t-test.

Results: Only 35.5% of MRI reports fully matched operative findings. MRI sensitivity was 71.0% for the ACL (22/31), 61.3% for the PCL (19/31), 93.5% for the MCL (29/31), 64.5% for the LCL (20/31), and 51.6% for the PLC (16/31). ANOVA revealed that MCL sensitivity was significantly higher than that of the PLC, PCL, and LCL. The difference in mean flexion ROM at final follow-up between accurate and inaccurate MRI cohorts was not statistically significant (p = 0.56).

Discussion: Preoperative MRI radiology reports demonstrated substantial limitations in accurately identifying ligamentous injuries in KDIV knee dislocations, particularly involving the PLC, PCL, and LCL. These findings highlight a gap between radiologic interpretation and surgical findings. Surgeons should interpret MRI reports with caution and incorporate fluoroscopic EUA at the time of surgery to ensure a comprehensive assessment of ligamentous damage.

膝关节脱位,特别是高度损伤,如Schenck级KDIV,是一种复杂的损伤,通常由高能创伤引起。虽然磁共振成像(MRI)被广泛用于术前评估韧带损伤,但其诊断准确性仍不确定。方法:回顾性分析在某一级创伤中心10年来接受膝关节脱位手术治疗的92例患者。包括术前MRI报告和术中确认无胫骨平台骨折的KDIV损伤的患者,共31例。通过比较麻醉下透视检查(EUA)对前交叉韧带(ACL)、后交叉韧带(PCL)、内侧副韧带(MCL)、外侧副韧带(LCL)和后外侧角(PLC)损伤的影像学报告和手术结果,确定MRI敏感性。回顾了术后随访文件的功能结局。采用单因素方差分析(ANOVA)来评估不同韧带类型敏感性的差异,随后采用Tukey事后检验进行两两比较。采用独立t检验比较准确和不准确MRI队列在最终随访(≥6个月)时的平均屈曲ROM。结果:只有35.5%的MRI报告完全符合手术表现。ACL(22/31)的MRI敏感性为71.0%,PCL(19/31)为61.3%,MCL(29/31)为93.5%,LCL(20/31)为64.5%,PLC(16/31)为51.6%。方差分析显示,MCL的敏感性显著高于PLC、PCL和LCL。准确和不准确MRI队列在最终随访时的平均屈曲ROM差异无统计学意义(p = 0.56)。讨论:术前MRI放射学报告显示,在准确识别KDIV膝关节脱位的韧带损伤方面存在很大的局限性,特别是涉及PLC, PCL和LCL。这些发现强调了放射学解释和外科发现之间的差距。外科医生应谨慎解释MRI报告,并在手术时结合透视EUA,以确保对韧带损伤进行全面评估。
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引用次数: 0
Reduction of oxidative stress in total knee arthroplasty using tourniquet with a novel pharmaceutical combination. 止血带与新型药物组合降低全膝关节置换术中的氧化应激。
IF 2.3 Q2 ORTHOPEDICS Pub Date : 2025-01-01 Epub Date: 2025-08-08 DOI: 10.1051/sicotj/2025042
Irini Tatani, Electra Kalaitzopoulou, Marianna Skipitari, Aristeidis Ntoukas, Eleni A Tsaliki, Savvas Giakoumakis, John Lakoumentas, Athina Varemmenou, Effimia Michail, Polyxeni Papadea, Christos D Georgiou, Elias Panagiotopoulos

Introduction: Tourniquet use in total knee arthroplasty (TKA) can cause ischaemia-reperfusion (I-R) injury via oxidative stress. This study evaluated whether combined administration of the antioxidant N-acetylcysteine (NAC) and the iron-chelator Deferiprone can mitigate oxidative damage and improve clinical outcomes.

Materials and methods: Twenty TKA patients were randomized into two groups, one group receiving NAC (600 mg, 6 h pre-op) and Deferiprone (1000 mg, 2 h pre-op) (intervention group) and the other group serving as placebo (control). Lipid hydroperoxides (LOOH) and protein malondialdehyde (PrMDA) were measured from quadriceps muscle tissue samples at 5 min (T1) and 40 min (T2) after tourniquet inflation, and 5 min after deflation (T3). Blood markers including serum ferritin, white blood cell (WBC) count, and polymorphonuclear neutrophils (PMNs) were assessed along with tissue PrMDA and LOOH as primary outcome measurements, while pain scores and knee flexion were recorded postoperatively as secondary outcome measurements.

Results: LOOH levels were significantly lower in the intervention group at T2 and T3. PrMDA levels showed no significant differences. Ferritin levels rose by 69% in controls vs. 18% in the intervention group. WBC and PMNs normalized faster, with reduced pain and improved range of motion in the intervention group.

Conclusion: The attenuation of LOOH elevation, the faster PMN deactivation, the inhibition of ferritin release from the cells along with the improved clinical outcomes suggest that combined NAC and Deferiprone administration may reduce tourniquet-related oxidative stress and inflammation, enhancing early recovery in TKA patients.

导读:在全膝关节置换术(TKA)中使用止血带可通过氧化应激引起缺血-再灌注(I-R)损伤。本研究评估了抗氧化剂n-乙酰半胱氨酸(NAC)和铁螯合剂去铁嘧啶(deiprone)联合使用是否能减轻氧化损伤并改善临床结果。材料与方法:将20例TKA患者随机分为两组,一组给予NAC (600 mg,术前6 h)和去铁素(1000 mg,术前2 h)作为干预组,另一组作为安慰剂(对照组)。在止血带充气后5 min (T1)、40 min (T2)和放气后5 min (T3)分别测定股四头肌组织样本的脂质氢过氧化物(LOOH)和蛋白丙二醛(PrMDA)。血液标志物包括血清铁蛋白、白细胞(WBC)计数和多形核中性粒细胞(pmn)与组织PrMDA和LOOH一起作为主要结果测量,而疼痛评分和膝关节屈曲作为次要结果测量记录在术后。结果:干预组在T2和T3时LOOH水平明显降低。PrMDA水平差异无统计学意义。对照组的铁蛋白水平上升了69%,干预组上升了18%。干预组WBC和pmn恢复正常更快,疼痛减轻,活动范围改善。结论:loh升高的减弱、PMN失活的加快、细胞铁蛋白释放的抑制以及临床预后的改善提示NAC联合去铁素可减轻止血带相关的氧化应激和炎症,促进TKA患者的早期恢复。
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引用次数: 0
Prevalence of low bone mineral density in robotic-assisted TKA candidates: insights from quantitative CT analysis. 机器人辅助TKA候选者中低骨密度的患病率:来自定量CT分析的见解。
IF 2.3 Q2 ORTHOPEDICS Pub Date : 2025-01-01 Epub Date: 2025-10-31 DOI: 10.1051/sicotj/2025048
Riccardo Garibaldi, Sébastien Lustig, Martinique Vella-Baldacchino, Paolo Ivan Fiore, Cécile Batailler

Introduction: Osteoporosis is a prevalent and often underdiagnosed condition that significantly increases the risk of fragility fractures. Dual-energy X-ray absorptiometry (DXA) is the standard diagnostic tool; however, many patients remain unscreened. Preoperative computed tomography (CT) scans obtained for robotic-assisted total knee arthroplasty (TKA) planning present an opportunity for opportunistic osteoporosis screening without additional radiation exposure.

Methods: A retrospective observational study was conducted on 637 patients (307 males, 330 females) who underwent robotic-assisted TKA between January 2023 and December 2024. Preoperative CT scans were analyzed using quantitative computed tomography (QCT) software to determine T-scores, Z-scores, and percentage of bone mineral density (BMD) relative to a young-adult reference. Patients were categorized as normal (T-score ≥ -1.0), osteopenic (-2.5 < T-score < -1.0), or osteoporotic (T-score ≤ -2.5).

Results: Among 597 patients with available T-score data, 41.0% were classified as normal, 32.3% as osteopenic, and 26.6% as osteoporotic. Notably, 37.0% of female patients were osteoporotic compared to 15.3% of male patients. Bone density parameters declined progressively with age, with females over 80 years exhibiting a mean T-score of -2.53 and BMD at 68.25% of the young-adult reference.

Discussion: Opportunistic screening using preoperative CT scans in robotic-assisted TKA patients reveals a high prevalence of undiagnosed low BMD, particularly among elderly women. Integrating QCT analysis into the preoperative workflow may facilitate early identification of at-risk individuals, informing surgical planning and enabling timely interventions to improve bone health.

骨质疏松症是一种普遍存在但常被误诊的疾病,它显著增加了脆性骨折的风险。双能x线吸收仪(DXA)是标准诊断工具;然而,许多患者仍未接受筛查。术前计算机断层扫描(CT)为机器人辅助全膝关节置换术(TKA)计划提供了机会性骨质疏松症筛查,而无需额外的辐射暴露。方法:对2023年1月至2024年12月期间接受机器人辅助TKA的637例患者(男性307例,女性330例)进行回顾性观察研究。术前CT扫描使用定量计算机断层扫描(QCT)软件进行分析,以确定相对于年轻人参考的t评分、z评分和骨密度(BMD)百分比。患者分为正常(t评分≥-1.0)、骨质减少(-2.5 < t评分< -1.0)和骨质疏松(t评分≤-2.5)。结果:在597例可获得t评分数据的患者中,41.0%为正常,32.3%为骨质减少,26.6%为骨质疏松。值得注意的是,女性患者骨质疏松率为37.0%,而男性患者为15.3%。骨密度参数随着年龄的增长而逐渐下降,80岁以上女性的平均t评分为-2.53,骨密度为青年人参考值的68.25%。讨论:机器人辅助TKA患者术前CT扫描的机会性筛查显示,未确诊的低骨密度患病率很高,特别是在老年女性中。将QCT分析整合到术前工作流程中可能有助于早期识别高危个体,为手术计划提供信息,并及时干预以改善骨骼健康。
{"title":"Prevalence of low bone mineral density in robotic-assisted TKA candidates: insights from quantitative CT analysis.","authors":"Riccardo Garibaldi, Sébastien Lustig, Martinique Vella-Baldacchino, Paolo Ivan Fiore, Cécile Batailler","doi":"10.1051/sicotj/2025048","DOIUrl":"10.1051/sicotj/2025048","url":null,"abstract":"<p><strong>Introduction: </strong>Osteoporosis is a prevalent and often underdiagnosed condition that significantly increases the risk of fragility fractures. Dual-energy X-ray absorptiometry (DXA) is the standard diagnostic tool; however, many patients remain unscreened. Preoperative computed tomography (CT) scans obtained for robotic-assisted total knee arthroplasty (TKA) planning present an opportunity for opportunistic osteoporosis screening without additional radiation exposure.</p><p><strong>Methods: </strong>A retrospective observational study was conducted on 637 patients (307 males, 330 females) who underwent robotic-assisted TKA between January 2023 and December 2024. Preoperative CT scans were analyzed using quantitative computed tomography (QCT) software to determine T-scores, Z-scores, and percentage of bone mineral density (BMD) relative to a young-adult reference. Patients were categorized as normal (T-score ≥ -1.0), osteopenic (-2.5 < T-score < -1.0), or osteoporotic (T-score ≤ -2.5).</p><p><strong>Results: </strong>Among 597 patients with available T-score data, 41.0% were classified as normal, 32.3% as osteopenic, and 26.6% as osteoporotic. Notably, 37.0% of female patients were osteoporotic compared to 15.3% of male patients. Bone density parameters declined progressively with age, with females over 80 years exhibiting a mean T-score of -2.53 and BMD at 68.25% of the young-adult reference.</p><p><strong>Discussion: </strong>Opportunistic screening using preoperative CT scans in robotic-assisted TKA patients reveals a high prevalence of undiagnosed low BMD, particularly among elderly women. Integrating QCT analysis into the preoperative workflow may facilitate early identification of at-risk individuals, informing surgical planning and enabling timely interventions to improve bone health.</p>","PeriodicalId":46378,"journal":{"name":"SICOT-J","volume":"11 ","pages":"57"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12578436/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145423145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of screw reinsertion on osteosynthesis stability in Schatzker IV tibial plateau fractures: a biomechanical study. Schatzker IV型胫骨平台骨折再钉对骨整合稳定性的影响:生物力学研究。
IF 1.8 Q2 ORTHOPEDICS Pub Date : 2025-01-01 Epub Date: 2025-02-27 DOI: 10.1051/sicotj/2025008
Shuhei Hiyama, Tsuneari Takahashi, Jiro Ando, Yoshiya Nibe, Tomohiro Matsumura, Katsushi Takeshita

Introduction: This biomechanical study evaluated the effect of screw reinsertion with a locking plate on fixation strength and the stability of osteosynthesis in medial tibial plateau fractures using porcine bone.

Materials and methods: Thirty porcine tibiae were divided into three groups: group A (underwent biomechanical testing after medial tibial fixation with a large fragment T-shaped locking plate), group B (underwent plate fixation, followed by the removal of all screws and plates and refixation with the same screws and plates using the same holes before biomechanical testing), and group C (underwent biomechanical testing once after plate fixation, followed by the removal of all screws and plates, refixation with the same screws and plates using the same holes, and then biomechanical testing). The translation pattern of the constructs in each group was examined using cyclic loading tests. The changes in the joint gap and step-off after 2000 cycles were compared among the three groups.

Results: Significant differences in displacement were observed at 10-100 cycles (group A: -0.01 ± 0.04 mm, group B: -0.02 ± 0.04 mm, group C: -0.13 ± 0.15 mm, P = 0.021). However, no significant differences were found in other displacement and translation measurements among the groups. Regarding the gap and step-off among groups, significant differences were observed in anterior and posterior gap changes. Despite the statistical significance, the absolute displacement values were small, suggesting minimal clinical relevance. These findings indicate that reinserting screws and plates into the same hole may not substantially compromise overall fixation strength.

Conclusion: Screw reinsertion in the same holes after removal did not significantly compromise the stability of osteosynthesis in this biomechanical model. These findings suggest that reinsertion may be a viable option in revision surgery.

简介:本生物力学研究评估了猪骨胫骨内侧平台骨折再置入锁定钢板螺钉对固定强度和骨合成稳定性的影响。材料与方法:30只猪胫骨分为3组:A组(胫骨内侧用大碎片t型锁定钢板固定后进行生物力学试验),B组(钢板固定后取出所有螺钉和钢板,在生物力学试验前使用相同孔用相同螺钉和钢板再固定),C组(钢板固定后进行一次生物力学试验,取出所有螺钉和钢板,使用相同孔用相同螺钉和钢板再固定。然后是生物力学测试)。采用循环加载试验检测各组构念的翻译模式。比较三组在2000个周期后关节间隙和步距的变化。结果:在10 ~ 100个周期内,位移量差异有统计学意义(A组:-0.01±0.04 mm, B组:-0.02±0.04 mm, C组:-0.13±0.15 mm, P = 0.021)。然而,在其他位移和平移测量中,各组之间没有发现显着差异。对于间隙和步离,组间前后间隙变化有显著性差异。尽管有统计学意义,但绝对位移值很小,表明临床相关性很小。这些结果表明,在同一孔内重新插入螺钉和钢板可能不会显著降低整体固定强度。结论:在该生物力学模型中,拆除后在相同孔内重新插入螺钉不会显著影响骨结合的稳定性。这些发现提示在翻修手术中重新插入可能是一个可行的选择。
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