{"title":"Cytomegalovirus infection in pregnancy: exploring screening strategies, prevalence rates, and impact on newborns in Turkey","authors":"","doi":"10.59215/prn.23.0312001","DOIUrl":"https://doi.org/10.59215/prn.23.0312001","url":null,"abstract":"","PeriodicalId":46449,"journal":{"name":"Journal of Perinatal Education","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87770272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Obut, Süleyman Cemil Oğlak, Özge Yücal Çelik, Şeyhmus Tunç, E. Öcal, Zeynep Gedik Özköse, Gökhan Bolluk, Sadun Sucu
Objective: This study aims to detect a relationship between inflammatory markers, ductus venosus (DV) pulsatility index (PI), middle cerebral artery (MCA) PI, and umbilical artery (UA) systole to diastole ratio (S/D) and PI between pregnancies with intrahepatic cholestasis and control cases. Methods: This prospective study included 82 cases having intrahepatic cholestasis of pregnancy (ICP) and 80 gestational age-matched healthy control cases. The Doppler measurements (DV PI, MCA PI, and UA S/D and PI), inflammatory markers (neutrophil to lymphocyte ratio [NLR], platelet to lymphocyte ratio [PLR], mean platelet volume [MPV], and red blood cell distribution width [RDW]), and fetal and maternal outcomes were compared. Results: Patients with ICP had increased PLR value (p=0.019) and decreased lymphocyte count (p=0.004) compared to control cases. Also, there was a positive correlation between PLR value and the presence of ICP (χ2=5.774, p=0.016). There were no significant differences between ICP and control groups concerning NLR, RDW, MPV, and UA PI values. We found higher UA S/D, and DV PI values and lower MCA PI values in pregnancies with ICP compared to controls (p<0.001, p=0.026, and p=0.003, respectively). Conclusion: In ICP cases, the PLR value was significantly increased than the controls, but the NLR, RDW, MPV, and UA PI values were found to be similar to control cases. The UA S/D, and DV PI values were increased, and MCA PI was significantly decreased in the ICP group compared to healthy pregnancies. However, we could not demonstrate the benefit of Doppler measurements in predicting neonatal outcomes in ICP cases.
{"title":"The comparison of systemic inflammatory response markers and Doppler ultrasound parameters between pregnancies with intrahepatic cholestasis and control cases","authors":"M. Obut, Süleyman Cemil Oğlak, Özge Yücal Çelik, Şeyhmus Tunç, E. Öcal, Zeynep Gedik Özköse, Gökhan Bolluk, Sadun Sucu","doi":"10.2399/prn.23.0311009","DOIUrl":"https://doi.org/10.2399/prn.23.0311009","url":null,"abstract":"Objective: This study aims to detect a relationship between inflammatory markers, ductus venosus (DV) pulsatility index (PI), middle cerebral artery (MCA) PI, and umbilical artery (UA) systole to diastole ratio (S/D) and PI between pregnancies with intrahepatic cholestasis and control cases. Methods: This prospective study included 82 cases having intrahepatic cholestasis of pregnancy (ICP) and 80 gestational age-matched healthy control cases. The Doppler measurements (DV PI, MCA PI, and UA S/D and PI), inflammatory markers (neutrophil to lymphocyte ratio [NLR], platelet to lymphocyte ratio [PLR], mean platelet volume [MPV], and red blood cell distribution width [RDW]), and fetal and maternal outcomes were compared. Results: Patients with ICP had increased PLR value (p=0.019) and decreased lymphocyte count (p=0.004) compared to control cases. Also, there was a positive correlation between PLR value and the presence of ICP (χ2=5.774, p=0.016). There were no significant differences between ICP and control groups concerning NLR, RDW, MPV, and UA PI values. We found higher UA S/D, and DV PI values and lower MCA PI values in pregnancies with ICP compared to controls (p<0.001, p=0.026, and p=0.003, respectively). Conclusion: In ICP cases, the PLR value was significantly increased than the controls, but the NLR, RDW, MPV, and UA PI values were found to be similar to control cases. The UA S/D, and DV PI values were increased, and MCA PI was significantly decreased in the ICP group compared to healthy pregnancies. However, we could not demonstrate the benefit of Doppler measurements in predicting neonatal outcomes in ICP cases.","PeriodicalId":46449,"journal":{"name":"Journal of Perinatal Education","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82494979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: The incidence of gestational diabetes mellitus (GDM) is increasing in parallel with maternal obesity. The main components of treatment are monitoring blood glucose levels with medical nutrition therapy and lifestyle modification in order to prevent short- and long-term materno-fetal complications. This study aimed to compare the diet quality and mindful eating among pregnant women with and without GDM. Methods: This case-control study included 68 pregnant women. Each participant was face-to-face interviewed using a structured questionnaire to obtain socio-demographic information, general health information, nutritional habits, and registered three days of food record. Mindful Eating Questionnaire (MEQ) and Healthy Eating Index (HEI) were applied in order to assess mindful eating and diet quality, respectively. Results: Mean pre-pregnancy body mass index of women was 27.42+5.44 kg/m2, 66.7% of the gestational diabetes group and 29.4% of the control group was obese. Differences in HEI adequacy subgroup scores between the groups were significant. Mean MEQ scores were 2.85±0.34 and 3.13±0.44 in pregnant women with gestational diabetes and control cases, respectively (r=0.61, p=0003, p<0.05). Conclusion: Our results showed that pregnant women with gestational diabetes had lower mindful eating and diet quality scores.
{"title":"Dietary quality and mindful eating among pregnant women with and without gestational diabetes","authors":"Hatice Nur Özbay, Sinem Bayram, Esen Yeşil","doi":"10.2399/prn.23.0311004","DOIUrl":"https://doi.org/10.2399/prn.23.0311004","url":null,"abstract":"Objective: The incidence of gestational diabetes mellitus (GDM) is increasing in parallel with maternal obesity. The main components of treatment are monitoring blood glucose levels with medical nutrition therapy and lifestyle modification in order to prevent short- and long-term materno-fetal complications. This study aimed to compare the diet quality and mindful eating among pregnant women with and without GDM. Methods: This case-control study included 68 pregnant women. Each participant was face-to-face interviewed using a structured questionnaire to obtain socio-demographic information, general health information, nutritional habits, and registered three days of food record. Mindful Eating Questionnaire (MEQ) and Healthy Eating Index (HEI) were applied in order to assess mindful eating and diet quality, respectively. Results: Mean pre-pregnancy body mass index of women was 27.42+5.44 kg/m2, 66.7% of the gestational diabetes group and 29.4% of the control group was obese. Differences in HEI adequacy subgroup scores between the groups were significant. Mean MEQ scores were 2.85±0.34 and 3.13±0.44 in pregnant women with gestational diabetes and control cases, respectively (r=0.61, p=0003, p<0.05). Conclusion: Our results showed that pregnant women with gestational diabetes had lower mindful eating and diet quality scores.","PeriodicalId":46449,"journal":{"name":"Journal of Perinatal Education","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87327635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aslı Altınordu Atcı, Şükran Doğru, Fatih Akkuş, Delal Akıncı, A. Acar
Objective: The aim of this study was to evaluate the maternal and neonatal outcomes of patients who underwent ultrasonography (USG) and emergency-indicated cerclage in the mid-trimester in singleton and twin pregnancies. Methods: A total of 55 patients, 43 with singleton and 12 with twin pregnancies who underwent cerclage for short cervix (<25 mm) or cervical dilation between January 2015 and December 2021 were included in the study. The primary outcome was gestational age at birth, and secondary outcomes were neonatal birth weight, the status of admission to neonatal intensive care unit, neonatal survival, and the neonatal birth rates at <24 weeks, 24–27⁺⁶ weeks, 28–33⁺⁶ weeks, 34–36⁺⁶ weeks and >37 weeks. Results: In singleton pregnancies, delivery interval was 15.05 (±2.9) weeks in the USG indication group and 2.8 (±2.5) weeks in the emergency indication group (p<0.001). The rate of pregnant women in the USG indication group who gave birth between 24–27⁺⁶ weeks of gestation was 4.9% (n=2), and the rate of pregnant women in the emergency indication group was 55.6% (n=5) (p<0.001). In total, in singleton pregnancies the rate of take-home baby was 85.7%, and neonatal mortality was 14.3%. In twin pregnancies, delivery interval was 12±1.41 weeks in the USG indication group, and it was 1.8±0.83 weeks in the emergency indication group (p<0.003). In twin pregnancies, the take-home baby rate was 94% and neonatal mortality was 6%. Conclusion: Cervical cerclage reduces the possible risks of preterm delivery by prolonging the interval until delivery, especially in patients with singleton and twin pregnancies for whom USG is indicated, and promising neonatal outcomes are achieved.
{"title":"Mid-trimester cerclage outcomes in singleton and twin pregnancies: a single tertiary center experience","authors":"Aslı Altınordu Atcı, Şükran Doğru, Fatih Akkuş, Delal Akıncı, A. Acar","doi":"10.2399/prn.23.0311010","DOIUrl":"https://doi.org/10.2399/prn.23.0311010","url":null,"abstract":"Objective: The aim of this study was to evaluate the maternal and neonatal outcomes of patients who underwent ultrasonography (USG) and emergency-indicated cerclage in the mid-trimester in singleton and twin pregnancies. Methods: A total of 55 patients, 43 with singleton and 12 with twin pregnancies who underwent cerclage for short cervix (<25 mm) or cervical dilation between January 2015 and December 2021 were included in the study. The primary outcome was gestational age at birth, and secondary outcomes were neonatal birth weight, the status of admission to neonatal intensive care unit, neonatal survival, and the neonatal birth rates at <24 weeks, 24–27⁺⁶ weeks, 28–33⁺⁶ weeks, 34–36⁺⁶ weeks and >37 weeks. Results: In singleton pregnancies, delivery interval was 15.05 (±2.9) weeks in the USG indication group and 2.8 (±2.5) weeks in the emergency indication group (p<0.001). The rate of pregnant women in the USG indication group who gave birth between 24–27⁺⁶ weeks of gestation was 4.9% (n=2), and the rate of pregnant women in the emergency indication group was 55.6% (n=5) (p<0.001). In total, in singleton pregnancies the rate of take-home baby was 85.7%, and neonatal mortality was 14.3%. In twin pregnancies, delivery interval was 12±1.41 weeks in the USG indication group, and it was 1.8±0.83 weeks in the emergency indication group (p<0.003). In twin pregnancies, the take-home baby rate was 94% and neonatal mortality was 6%. Conclusion: Cervical cerclage reduces the possible risks of preterm delivery by prolonging the interval until delivery, especially in patients with singleton and twin pregnancies for whom USG is indicated, and promising neonatal outcomes are achieved.","PeriodicalId":46449,"journal":{"name":"Journal of Perinatal Education","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91161266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bilge Keskinsoy, Bengü Mutlu Sütçüoğlu, Halis Özdemir, M. Bayram
Objective: We aimed to evaluate the differences in obstetrics and neonatal outcomes, such as mode of delivery, gestational diabetes mellitus, preeclampsia, and infant birth weight between pregnancies with normal and insufficient vitamin D levels. Methods: The study was designed as a retrospective study. One hundred and seventy-nine pregnant women who were followed up at our clinic and whose vitamin D levels were evaluated in each trimester were included. All patients were administered 1200 IU/day beginning from the 12 weeks of gestation in accordance with the national guidelines. Vitamin D levels above 20 ng/ml were defined as sufficient, and those below 20 ng/ml were defined as insufficient. Results: The median vitamin D level in the third trimester was significantly higher than that in the first and second trimesters (p<0.001). There was a moderate positive correlation between vitamin D levels in infant cord blood at the time of birth and vitamin D levels in the third trimester (p<0.001, R=0.496). Birth weights of the patients with insufficient vitamin D levels in the first trimester but with sufficient neonatal cord blood levels as a result of treatment were significantly higher compared to those in patients with insufficient cord blood vitamin D levels (3327 g vs. 3133 g, p=0.030). Conclusion: This study observed that neonatal cord blood vitamin D level is a better indicator than antenatal vitamin D levels. Regardless of first-trimester vitamin D levels, infant birth weights were significantly higher in the group with sufficient neonatal cord blood levels.
{"title":"Vitamin D levels in pregnancies and neonatal outcomes","authors":"Bilge Keskinsoy, Bengü Mutlu Sütçüoğlu, Halis Özdemir, M. Bayram","doi":"10.2399/prn.23.0311005","DOIUrl":"https://doi.org/10.2399/prn.23.0311005","url":null,"abstract":"Objective: We aimed to evaluate the differences in obstetrics and neonatal outcomes, such as mode of delivery, gestational diabetes mellitus, preeclampsia, and infant birth weight between pregnancies with normal and insufficient vitamin D levels. Methods: The study was designed as a retrospective study. One hundred and seventy-nine pregnant women who were followed up at our clinic and whose vitamin D levels were evaluated in each trimester were included. All patients were administered 1200 IU/day beginning from the 12 weeks of gestation in accordance with the national guidelines. Vitamin D levels above 20 ng/ml were defined as sufficient, and those below 20 ng/ml were defined as insufficient. Results: The median vitamin D level in the third trimester was significantly higher than that in the first and second trimesters (p<0.001). There was a moderate positive correlation between vitamin D levels in infant cord blood at the time of birth and vitamin D levels in the third trimester (p<0.001, R=0.496). Birth weights of the patients with insufficient vitamin D levels in the first trimester but with sufficient neonatal cord blood levels as a result of treatment were significantly higher compared to those in patients with insufficient cord blood vitamin D levels (3327 g vs. 3133 g, p=0.030). Conclusion: This study observed that neonatal cord blood vitamin D level is a better indicator than antenatal vitamin D levels. Regardless of first-trimester vitamin D levels, infant birth weights were significantly higher in the group with sufficient neonatal cord blood levels.","PeriodicalId":46449,"journal":{"name":"Journal of Perinatal Education","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87069749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: To compare Fenton and Intergrowth-21st growth charts in assessing the growth pattern of preterm infants at birth and at discharge. Methods: This is a retrospective study conducted over a period of 1 year. The study included the neonates born at ≤34 weeks of gestation who are admitted and stayed for ≥14 days in our hospital. The data was collected from discharge sheets and electronic database. The weight of all babies at birth and at discharge was collected. Growth was assessed based on Fenton and Intergrowth-21st growth charts. The small for gestational age (SGA) was defined as birth weight ≤-1.28SD. The extrauterine growth restriction (EUGR) status of babies was assessed by a criteria of ≤-1.28SD at discharge. Results: Most common preterm phenotype was spontaneous preterm labor (47.4%), and the rate of singleton birth was 78.9%. The mean gestational age and birth weight of babies were 31.6±1.42 weeks and 1608.06±275 g, respectively. We found the rates of SGA in our group 15.2% and 13.5%, and appropriate for gestational age (AGA) 80.5% and 82.2%, respectively by using Intergrowth and Fenton growth charts. The EUGR rates in our group were 72.8% and 81.3%, respectively, on Intergrowth-21st and Fenton growth charts using a criteria of ≤-1.28SD at discharge. Conclusion: There is no statistical difference between Fenton and Intergrowth-21st charts in identifying SGA and EUGR. However, the rate of EUGR is higher in Fenton charts than intergrowth-21st charts.
{"title":"Comparison of Fenton and Intergrowth-21st growth charts: a retrospective study of preterm neonates at ≤34 weeks","authors":"K. Haridas, M. Solaiappan, Muthukumaran Natarajan","doi":"10.2399/prn.23.0311002","DOIUrl":"https://doi.org/10.2399/prn.23.0311002","url":null,"abstract":"Objective: To compare Fenton and Intergrowth-21st growth charts in assessing the growth pattern of preterm infants at birth and at discharge. Methods: This is a retrospective study conducted over a period of 1 year. The study included the neonates born at ≤34 weeks of gestation who are admitted and stayed for ≥14 days in our hospital. The data was collected from discharge sheets and electronic database. The weight of all babies at birth and at discharge was collected. Growth was assessed based on Fenton and Intergrowth-21st growth charts. The small for gestational age (SGA) was defined as birth weight ≤-1.28SD. The extrauterine growth restriction (EUGR) status of babies was assessed by a criteria of ≤-1.28SD at discharge. Results: Most common preterm phenotype was spontaneous preterm labor (47.4%), and the rate of singleton birth was 78.9%. The mean gestational age and birth weight of babies were 31.6±1.42 weeks and 1608.06±275 g, respectively. We found the rates of SGA in our group 15.2% and 13.5%, and appropriate for gestational age (AGA) 80.5% and 82.2%, respectively by using Intergrowth and Fenton growth charts. The EUGR rates in our group were 72.8% and 81.3%, respectively, on Intergrowth-21st and Fenton growth charts using a criteria of ≤-1.28SD at discharge. Conclusion: There is no statistical difference between Fenton and Intergrowth-21st charts in identifying SGA and EUGR. However, the rate of EUGR is higher in Fenton charts than intergrowth-21st charts.","PeriodicalId":46449,"journal":{"name":"Journal of Perinatal Education","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79986288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: The study aimed to identify the effects of restless legs syndrome (RLS) on sleep quality and quality of life in pregnant women.Methods: This comparative and descriptive study was conducted with 109 pregnant women between the 24 and 39 weeks of gestation. The presence and severity of RLS were investigated using the International Restless Legs Syndrome Study Group’s Diagnostic Criteria Scale and Severity Rating Scale, and the effects of the syndrome on sleep and quality of life were evaluated. Results: The prevalence of RLS in pregnant women was found to be 47.7%. In the RLS group, 22.0% of the pregnant women had severe RLS symptoms and 20.2% had moderate RLS symptoms. The mean score for Restless Legs Syndrome Severity Rating Scale was determined 20.75±6.38. The mean score for quality of life scale was determined 17.75±3.73 in RLS group and 26.46±2.67 in non-RLS group. Conclusion: The difference between the mean scores for Pittsburgh Sleep Quality Index of the pregnant women with RLS and those without the syndrome was found to be statistically significant. While the mean score for Quality of Life Scale in pregnant women with RLS was lower in general health, physical health and psychological health sub-dimensions, no statistically significant difference was found in social relations and environment sub-dimensions. It is recommended that nurses investigate RLS complaints of pregnant women and include non-pharmacological methods in their nursing practices.
{"title":"The effects of restless legs syndrome on sleep and quality of life during pregnancy: a comparative descriptive study","authors":"İffet Güler Kaya, D. Koçak","doi":"10.2399/prn.23.0311008","DOIUrl":"https://doi.org/10.2399/prn.23.0311008","url":null,"abstract":"Objective: The study aimed to identify the effects of restless legs syndrome (RLS) on sleep quality and quality of life in pregnant women.Methods: This comparative and descriptive study was conducted with 109 pregnant women between the 24 and 39 weeks of gestation. The presence and severity of RLS were investigated using the International Restless Legs Syndrome Study Group’s Diagnostic Criteria Scale and Severity Rating Scale, and the effects of the syndrome on sleep and quality of life were evaluated. Results: The prevalence of RLS in pregnant women was found to be 47.7%. In the RLS group, 22.0% of the pregnant women had severe RLS symptoms and 20.2% had moderate RLS symptoms. The mean score for Restless Legs Syndrome Severity Rating Scale was determined 20.75±6.38. The mean score for quality of life scale was determined 17.75±3.73 in RLS group and 26.46±2.67 in non-RLS group. Conclusion: The difference between the mean scores for Pittsburgh Sleep Quality Index of the pregnant women with RLS and those without the syndrome was found to be statistically significant. While the mean score for Quality of Life Scale in pregnant women with RLS was lower in general health, physical health and psychological health sub-dimensions, no statistically significant difference was found in social relations and environment sub-dimensions. It is recommended that nurses investigate RLS complaints of pregnant women and include non-pharmacological methods in their nursing practices.","PeriodicalId":46449,"journal":{"name":"Journal of Perinatal Education","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80411109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prenatal diagnosis and pregnancy outcomes of 149 fetuses with tetralogy of Fallot accompanied by concomitant cardiac and extracardiac anomalies","authors":"Gökhan Bolluk, Ö. Özdemir, H. Bornaun","doi":"10.2399/prn.22.0303008","DOIUrl":"https://doi.org/10.2399/prn.22.0303008","url":null,"abstract":"","PeriodicalId":46449,"journal":{"name":"Journal of Perinatal Education","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78678477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kazım Öztarhan, Talya Kaptaç, M. Karkucak, Ece Öztarhan, A. Gedikbaşı
{"title":"Jacobsen syndrome: a case report and clinical features of a rare genetic syndrome","authors":"Kazım Öztarhan, Talya Kaptaç, M. Karkucak, Ece Öztarhan, A. Gedikbaşı","doi":"10.2399/prn.22.0303006","DOIUrl":"https://doi.org/10.2399/prn.22.0303006","url":null,"abstract":"","PeriodicalId":46449,"journal":{"name":"Journal of Perinatal Education","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78779373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Işıkalan, Buşra Özkaya, Eren Berkay Özkaya, Erzat Toprak, Enes Ferlibaş, N. Şengül, A. Acar
Objective: The aim was to investigate how the duration of induction affects postabortion hemorrhage in second-trimester pregnancy termina- tions using misoprostol. Methods: This single-center retrospective cohort study was conducted between April 2020 and April 2021 at a university hospital. Singleton pregnant women having gestational age of 13–26 weeks and being hospitalized for termination were included in the study. The misoprostol was administered 200 μg every 4 hours intravaginally to patients already diagnosed with miscarriage, and 400 μg every 3 hours to all remaining patients. Estimated blood loss volume (EBLV) was calculated using a formula previously defined by Stafford et al. A total of 117 singleton pregnant women having gestational age of 13–26 weeks and being hospitalized for pregnancy termination were included in the study. Of these, 78 patients aborted within 0–24 hours (Group 2). The remaining 39 patients aborted in more than 24 hours (Group 1). Results: The EBLV was higher in the study group (p=0.003). In addition, the rate of patients with ≥ 500 cc and ≥ 1000 cc blood loss was also significantly higher in the study group (p values 0.049 and 0.016, respectively). After adjusting for potential confounder factors, the probability of blood loss of ≥ 500 cc and ≥ 1000 cc was found to be higher in the study group (adjusted OR: 2.720, 95% CI: 1.12–6.58 and adjusted OR: 6.987, 95% CI: 1.25–38.98, respectively). Conclusion: Postabortion hemorrhage risk was found to be higher in patients whose induction period lasted longer than 24 hours in sec-ond-trimester terminations with misoprostol. However, there was no deterioration in the patient’s clinical status and no increase in transfusion rates. Care should be taken with regard to vaginal bleeding in misoprostol applications lasting longer than 24 hours.
{"title":"The effect of induction duration on postabortal hemorrhage in second-trimester pregnancy termination with misoprostol","authors":"M. Işıkalan, Buşra Özkaya, Eren Berkay Özkaya, Erzat Toprak, Enes Ferlibaş, N. Şengül, A. Acar","doi":"10.2399/prn.22.0303001","DOIUrl":"https://doi.org/10.2399/prn.22.0303001","url":null,"abstract":"Objective: The aim was to investigate how the duration of induction affects postabortion hemorrhage in second-trimester pregnancy termina- tions using misoprostol. Methods: This single-center retrospective cohort study was conducted between April 2020 and April 2021 at a university hospital. Singleton pregnant women having gestational age of 13–26 weeks and being hospitalized for termination were included in the study. The misoprostol was administered 200 μg every 4 hours intravaginally to patients already diagnosed with miscarriage, and 400 μg every 3 hours to all remaining patients. Estimated blood loss volume (EBLV) was calculated using a formula previously defined by Stafford et al. A total of 117 singleton pregnant women having gestational age of 13–26 weeks and being hospitalized for pregnancy termination were included in the study. Of these, 78 patients aborted within 0–24 hours (Group 2). The remaining 39 patients aborted in more than 24 hours (Group 1). Results: The EBLV was higher in the study group (p=0.003). In addition, the rate of patients with ≥ 500 cc and ≥ 1000 cc blood loss was also significantly higher in the study group (p values 0.049 and 0.016, respectively). After adjusting for potential confounder factors, the probability of blood loss of ≥ 500 cc and ≥ 1000 cc was found to be higher in the study group (adjusted OR: 2.720, 95% CI: 1.12–6.58 and adjusted OR: 6.987, 95% CI: 1.25–38.98, respectively). Conclusion: Postabortion hemorrhage risk was found to be higher in patients whose induction period lasted longer than 24 hours in sec-ond-trimester terminations with misoprostol. However, there was no deterioration in the patient’s clinical status and no increase in transfusion rates. Care should be taken with regard to vaginal bleeding in misoprostol applications lasting longer than 24 hours.","PeriodicalId":46449,"journal":{"name":"Journal of Perinatal Education","volume":null,"pages":null},"PeriodicalIF":0.6,"publicationDate":"2022-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87353212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：