首页 > 最新文献

HIV AIDS-Research and Palliative Care最新文献

英文 中文
Health Care Needs Among People Living with HIV: The Implication of Continuum of Care. 艾滋病毒感染者的卫生保健需求:持续护理的含义。
IF 1.5 Q4 INFECTIOUS DISEASES Pub Date : 2023-01-01 DOI: 10.2147/HIV.S403510
Kusman Ibrahim, Laili Rahayuwati, Yusshy Kurnia Herliani, Iqbal Pramukti

Background: Human immunodeficiency virus remains a major public health problem in Indonesia. People living with HIV (PLWH) have various health problems as result from disease progression that impacts their health care needs. This study aims to explore health care needs and to test the factors associated with health care needs among people living with HIV.

Methods: A cross-sectional descriptive study design was undertaken with 243 respondents completing a self-reported HIV-Health Care Need Questionnaire. Participants were recruited using the purposive sampling technique from six HIV clinics in West Java, Indonesia. The data were analyzed using descriptive and multiple logistic regression statistical techniques.

Results: The majority of the subjects were diagnosed within less than 5 years and have been receiving antiretroviral therapy. Nursing care was indicated as the most needed, offered, and received care. Emergency financial assistance, legal services, insurance premiums, and nutritional intervention were perceived as gaps between needed and received. Characteristics such as age, educational background, having HIV manager, and income were significantly correlated to nutritional care (p< 0.05). Nutritional care was increased by 3.96% if PLWH having HIV manager (CI: 1.17-13.38, p< 0.05).

Conclusion: Addressing the gap between health care needs and health offered was important to ensure that care was received appropriately. Continuing assessment of health care needs can provide direction to deliver appropriate care and ensure a comprehensive continuum of care for PLWH.

背景:人类免疫缺陷病毒仍然是印度尼西亚的一个主要公共卫生问题。艾滋病毒感染者由于疾病进展而出现各种健康问题,影响了他们的卫生保健需求。本研究旨在探讨艾滋病毒感染者的卫生保健需求,并测试与卫生保健需求相关的因素。方法:采用横断面描述性研究设计,243名受访者完成自我报告的艾滋病毒卫生保健需求问卷。采用有目的抽样技术从印度尼西亚西爪哇的六个艾滋病毒诊所招募参与者。使用描述性和多元逻辑回归统计技术对数据进行分析。结果:大多数患者在5年内确诊,并一直接受抗逆转录病毒治疗。护理被认为是最需要、提供和接受的护理。紧急财政援助、法律服务、保险费和营养干预被认为是需求与接受之间的差距。年龄、学历、有HIV管理人员、收入等特征与营养护理有显著相关(p< 0.05)。有HIV管理人员的妇女的营养护理提高了3.96% (CI: 1.17 ~ 13.38, p< 0.05)。结论:解决卫生保健需求与提供的卫生保健之间的差距对于确保适当地获得卫生保健非常重要。对卫生保健需求的持续评估可以为提供适当的护理提供指导,并确保为PLWH提供全面的连续护理。
{"title":"Health Care Needs Among People Living with HIV: The Implication of Continuum of Care.","authors":"Kusman Ibrahim,&nbsp;Laili Rahayuwati,&nbsp;Yusshy Kurnia Herliani,&nbsp;Iqbal Pramukti","doi":"10.2147/HIV.S403510","DOIUrl":"https://doi.org/10.2147/HIV.S403510","url":null,"abstract":"<p><strong>Background: </strong>Human immunodeficiency virus remains a major public health problem in Indonesia. People living with HIV (PLWH) have various health problems as result from disease progression that impacts their health care needs. This study aims to explore health care needs and to test the factors associated with health care needs among people living with HIV.</p><p><strong>Methods: </strong>A cross-sectional descriptive study design was undertaken with 243 respondents completing a self-reported HIV-Health Care Need Questionnaire. Participants were recruited using the purposive sampling technique from six HIV clinics in West Java, Indonesia. The data were analyzed using descriptive and multiple logistic regression statistical techniques.</p><p><strong>Results: </strong>The majority of the subjects were diagnosed within less than 5 years and have been receiving antiretroviral therapy. Nursing care was indicated as the most needed, offered, and received care. Emergency financial assistance, legal services, insurance premiums, and nutritional intervention were perceived as gaps between needed and received. Characteristics such as age, educational background, having HIV manager, and income were significantly correlated to nutritional care (p< 0.05). Nutritional care was increased by 3.96% if PLWH having HIV manager (CI: 1.17-13.38, p< 0.05).</p><p><strong>Conclusion: </strong>Addressing the gap between health care needs and health offered was important to ensure that care was received appropriately. Continuing assessment of health care needs can provide direction to deliver appropriate care and ensure a comprehensive continuum of care for PLWH.</p>","PeriodicalId":46555,"journal":{"name":"HIV AIDS-Research and Palliative Care","volume":"15 ","pages":"235-246"},"PeriodicalIF":1.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7e/f5/hiv-15-235.PMC10204712.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9527025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictors of an Active Lifestyle in Middle-Aged and Older Adults with HIV in the United States Deep South. 美国南部腹地中老年HIV感染者积极生活方式的预测因素。
IF 1.5 Q4 INFECTIOUS DISEASES Pub Date : 2023-01-01 DOI: 10.2147/HIV.S399842
Wei Li, Pariya L Fazeli, Ge Wang, Muhammad Maqbool, Victor A Del Bene, Kristen Triebel, Karli M Martin, David Vance

Background and purpose: An active lifestyle is important for health maintenance and disease prevention. This study was to examine what factors predict an active lifestyle in HIV+ and HIV- adults from the United States Deep South.

Methods: The sample included 279 participants (174 HIV+ and 105 HIV-) who completed a comprehensive assessment. An active lifestyle composite was created using variables of employment status, level of social support, level of physical activity, and diet. Correlations and regression analyses were conducted between the active lifestyle composite and possible predictors for all (HIV+ and HIV-), HIV+, and HIV- participants, respectively.

Results: Lower levels of depression, higher socioeconomic status (SES), and younger age were significant predictors of a more active lifestyle for the full sample, HIV+, and HIV- participants, respectively.

Conclusion: SES and depression represent important factors influencing engagement in an active lifestyle in PLWH. Such factors should be considered when developing and implementing lifestyle interventions.

背景和目的:积极的生活方式对保持健康和预防疾病很重要。这项研究是为了研究哪些因素可以预测来自美国南部腹地的HIV阳性和HIV阳性成年人积极的生活方式。方法:279名参与者(174名HIV阳性和105名HIV阴性)完成了综合评估。使用就业状况、社会支持水平、身体活动水平和饮食等变量创建了积极的生活方式组合。分别对所有(HIV+和HIV-)、HIV+和HIV-参与者的积极生活方式组合与可能的预测因子进行相关性和回归分析。结果:较低的抑郁水平、较高的社会经济地位(SES)和较年轻的年龄分别是全样本、HIV+和HIV-参与者更积极的生活方式的重要预测因素。结论:社会经济状况和抑郁是影响PLWH患者积极生活方式参与的重要因素。在制定和实施生活方式干预措施时应考虑这些因素。
{"title":"Predictors of an Active Lifestyle in Middle-Aged and Older Adults with HIV in the United States Deep South.","authors":"Wei Li,&nbsp;Pariya L Fazeli,&nbsp;Ge Wang,&nbsp;Muhammad Maqbool,&nbsp;Victor A Del Bene,&nbsp;Kristen Triebel,&nbsp;Karli M Martin,&nbsp;David Vance","doi":"10.2147/HIV.S399842","DOIUrl":"https://doi.org/10.2147/HIV.S399842","url":null,"abstract":"<p><strong>Background and purpose: </strong>An active lifestyle is important for health maintenance and disease prevention. This study was to examine what factors predict an active lifestyle in HIV+ and HIV- adults from the United States Deep South.</p><p><strong>Methods: </strong>The sample included 279 participants (174 HIV+ and 105 HIV-) who completed a comprehensive assessment. An active lifestyle composite was created using variables of employment status, level of social support, level of physical activity, and diet. Correlations and regression analyses were conducted between the active lifestyle composite and possible predictors for all (HIV+ and HIV-), HIV+, and HIV- participants, respectively.</p><p><strong>Results: </strong>Lower levels of depression, higher socioeconomic status (SES), and younger age were significant predictors of a more active lifestyle for the full sample, HIV+, and HIV- participants, respectively.</p><p><strong>Conclusion: </strong>SES and depression represent important factors influencing engagement in an active lifestyle in PLWH. Such factors should be considered when developing and implementing lifestyle interventions.</p>","PeriodicalId":46555,"journal":{"name":"HIV AIDS-Research and Palliative Care","volume":"15 ","pages":"63-70"},"PeriodicalIF":1.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2f/7b/hiv-15-63.PMC9987220.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9137281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Management of Type 2 Diabetes Mellitus and Kidney Failure in People with HIV-Infection in Africa: Current Status and a Call to Action. 非洲艾滋病毒感染者2型糖尿病和肾衰竭的管理:现状和行动呼吁
IF 1.5 Q4 INFECTIOUS DISEASES Pub Date : 2023-01-01 DOI: 10.2147/HIV.S396949
Nicola Wearne, Bianca Davidson, Marc Blockman, Jackie Jones, Ian L Ross, Joel A Dave

There is an increasing global burden of diabetes mellitus (DM) and chronic kidney disease (CKD), coupled with a high burden of people with HIV (PWH). Due to an increased lifespan on ART, PWH are now at risk of developing non-communicable diseases, including DM. Africa has the greatest burden of HIV infection and will experience the greatest increase in prevalence of DM over the next two decades. In addition, there is a rising number of people with CKD and progression to kidney failure. Therefore, there is an urgent need for the early identification and management of all 3 diseases to prevent disease progression and complications. This is particularly important in Africa for people with CKD where there is restricted or no access to dialysis and/or transplantation. This review focuses on the epidemiology and pathophysiology of the interaction between HIV infection and DM and the impact that these diseases have on the development and progression of CKD. Finally, it also aims to review the data on the management, which stems from the growing burden of all three diseases.

糖尿病(DM)和慢性肾脏疾病(CKD)的全球负担不断增加,加上艾滋病毒感染者(PWH)的高负担。由于接受抗逆转录病毒治疗的寿命延长,产妇现在面临罹患非传染性疾病(包括糖尿病)的风险。非洲是艾滋病毒感染负担最重的地区,在未来20年,糖尿病流行率将出现最大增幅。此外,越来越多的人患有慢性肾病并进展为肾衰竭。因此,迫切需要对所有3种疾病进行早期识别和管理,以防止疾病进展和并发症。这在非洲对于CKD患者尤其重要,因为那里的透析和/或移植受到限制或无法获得。本文综述了HIV感染与糖尿病相互作用的流行病学和病理生理学,以及这些疾病对CKD发生发展的影响。最后,它还旨在审查有关管理的数据,这些数据源于这三种疾病日益增加的负担。
{"title":"Management of Type 2 Diabetes Mellitus and Kidney Failure in People with HIV-Infection in Africa: Current Status and a Call to Action.","authors":"Nicola Wearne,&nbsp;Bianca Davidson,&nbsp;Marc Blockman,&nbsp;Jackie Jones,&nbsp;Ian L Ross,&nbsp;Joel A Dave","doi":"10.2147/HIV.S396949","DOIUrl":"https://doi.org/10.2147/HIV.S396949","url":null,"abstract":"<p><p>There is an increasing global burden of diabetes mellitus (DM) and chronic kidney disease (CKD), coupled with a high burden of people with HIV (PWH). Due to an increased lifespan on ART, PWH are now at risk of developing non-communicable diseases, including DM. Africa has the greatest burden of HIV infection and will experience the greatest increase in prevalence of DM over the next two decades. In addition, there is a rising number of people with CKD and progression to kidney failure. Therefore, there is an urgent need for the early identification and management of all 3 diseases to prevent disease progression and complications. This is particularly important in Africa for people with CKD where there is restricted or no access to dialysis and/or transplantation. This review focuses on the epidemiology and pathophysiology of the interaction between HIV infection and DM and the impact that these diseases have on the development and progression of CKD. Finally, it also aims to review the data on the management, which stems from the growing burden of all three diseases.</p>","PeriodicalId":46555,"journal":{"name":"HIV AIDS-Research and Palliative Care","volume":"15 ","pages":"519-535"},"PeriodicalIF":1.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ad/84/hiv-15-519.PMC10493098.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10242409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HIV Testing Uptake Among Ethiopian Rural Men: Evidence from 2016 Ethiopian Demography and Health Survey Data. 埃塞俄比亚农村男性接受艾滋病毒检测:来自2016年埃塞俄比亚人口和健康调查数据的证据
IF 1.5 Q4 INFECTIOUS DISEASES Pub Date : 2023-01-01 DOI: 10.2147/HIV.S409152
Melash Belachew Asresie, Getasew Tadesse Worku, Yibeltal Alemu Bekele

Background: Human immunodeficiency virus (HIV) testing coverage among men remains low in Ethiopia; the problem of limited HIV testing coverage is worst in rural areas. Therefore, this study aims to identify factors associated with HIV testing uptake among rural men in Ethiopia.

Methods: Data from 10,187 rural men was extracted from the 2016 Ethiopian Demography and Health Survey. All analyses were performed using the complex sample analysis procedure to account for the multistage sampling. Bivariable and multivariable regression analyses were performed to identify factors associated with HIV testing uptake. Statistical significance was defined as a 95% Confidence Interval (CI) with a p-value of less than 0.05.

Results: Overall, only 40.3% of rural men have ever been tested for HIV. Being aged 31-44 years (Adjusted Odds Ratio (AOR) =1.12, 95% CI [1.01-1.42]), living in developed regions (AOR=1.43, 95% CI [1.09-1.88]), engaging in non-agricultural activities (AOR = 1.27, 95% CI [1.05-1.52]), being Muslim (AOR = 2.07; 95% CI [1.67-2.67]), having comprehensive knowledge about HIV (AOR =1.31, 95% CI [1.12-1.54]), being from a medium (AOR = 0.56, 95% CI [0.47-0.93]) and rich (AOR = 0.80, 95% CI [0.56-0.80]) households, attending primary (AOR = 0.21, 95% CI [0.16-0.28]) and secondary (AOR = 0.35, 95% CI [0.25-0.35]) school, having their first sexual experience at the age of 17 or younger (AOR = 0.26, 95% CI [0.19-0.93]), having discriminatory attitudes towards HIV patients (AOR = 0.67, 95% CI: 0.47-0.93) and having no health insurance coverage (AOR = 0.54, 95% CI [0.42-0.69]) were significantly associated with HIV testing uptake.

Conclusion: HIV testing uptake among rural men was low. Strengthening awareness programmes on HIV and HIV testing, integrating HIV testing with all other healthcare, strengthening partner accompany and HIV testing during pregnancy and delivery, and providing home-based HIV testing may increase HIV testing uptake.

背景:在埃塞俄比亚,人类免疫缺陷病毒(HIV)检测在男性中的覆盖率仍然很低;艾滋病毒检测覆盖面有限的问题在农村地区最为严重。因此,本研究旨在确定埃塞俄比亚农村男性接受艾滋病毒检测的相关因素。方法:从2016年埃塞俄比亚人口与健康调查中提取10187名农村男性的数据。所有的分析都是使用复杂的样本分析程序进行的,以解释多阶段采样。进行了双变量和多变量回归分析,以确定与HIV检测吸收相关的因素。统计学显著性定义为95%置信区间(CI), p值小于0.05。结果:总体而言,只有40.3%的农村男性接受过艾滋病毒检测。年龄31-44岁(调整优势比(AOR) =1.12, 95% CI[1.01-1.42]),生活在发达地区(AOR=1.43, 95% CI[1.09-1.88]),从事非农业活动(AOR= 1.27, 95% CI[1.05-1.52]),为穆斯林(AOR= 2.07;(AOR =1.31, 95% CI[1.12-1.54]),来自中等家庭(AOR = 0.56, 95% CI[0.47-0.93])和富裕家庭(AOR = 0.80, 95% CI[0.56-0.80]),上小学(AOR = 0.21, 95% CI[0.16-0.28])和中学(AOR = 0.35, 95% CI[0.25-0.35]), 17岁或以下有第一次性经历(AOR = 0.26, 95% CI[0.19-0.93]),对艾滋病毒患者有歧视态度(AOR = 0.67, 95% CI:0.47-0.93)和没有医疗保险(AOR = 0.54, 95% CI[0.42-0.69])与艾滋病毒检测的接受程度显著相关。结论:农村男性艾滋病病毒检测接受率较低。加强对艾滋病毒和艾滋病毒检测的认识方案,将艾滋病毒检测与所有其他保健结合起来,在怀孕和分娩期间加强伴侣陪伴和艾滋病毒检测,以及提供家庭艾滋病毒检测,可能会增加艾滋病毒检测的接受程度。
{"title":"HIV Testing Uptake Among Ethiopian Rural Men: Evidence from 2016 Ethiopian Demography and Health Survey Data.","authors":"Melash Belachew Asresie,&nbsp;Getasew Tadesse Worku,&nbsp;Yibeltal Alemu Bekele","doi":"10.2147/HIV.S409152","DOIUrl":"https://doi.org/10.2147/HIV.S409152","url":null,"abstract":"<p><strong>Background: </strong>Human immunodeficiency virus (HIV) testing coverage among men remains low in Ethiopia; the problem of limited HIV testing coverage is worst in rural areas. Therefore, this study aims to identify factors associated with HIV testing uptake among rural men in Ethiopia.</p><p><strong>Methods: </strong>Data from 10,187 rural men was extracted from the 2016 Ethiopian Demography and Health Survey. All analyses were performed using the complex sample analysis procedure to account for the multistage sampling. Bivariable and multivariable regression analyses were performed to identify factors associated with HIV testing uptake. Statistical significance was defined as a 95% Confidence Interval (CI) with a p-value of less than 0.05.</p><p><strong>Results: </strong>Overall, only 40.3% of rural men have ever been tested for HIV. Being aged 31-44 years (Adjusted Odds Ratio (AOR) =1.12, 95% CI [1.01-1.42]), living in developed regions (AOR=1.43, 95% CI [1.09-1.88]), engaging in non-agricultural activities (AOR = 1.27, 95% CI [1.05-1.52]), being Muslim (AOR = 2.07; 95% CI [1.67-2.67]), having comprehensive knowledge about HIV (AOR =1.31, 95% CI [1.12-1.54]), being from a medium (AOR = 0.56, 95% CI [0.47-0.93]) and rich (AOR = 0.80, 95% CI [0.56-0.80]) households, attending primary (AOR = 0.21, 95% CI [0.16-0.28]) and secondary (AOR = 0.35, 95% CI [0.25-0.35]) school, having their first sexual experience at the age of 17 or younger (AOR = 0.26, 95% CI [0.19-0.93]), having discriminatory attitudes towards HIV patients (AOR = 0.67, 95% CI: 0.47-0.93) and having no health insurance coverage (AOR = 0.54, 95% CI [0.42-0.69]) were significantly associated with HIV testing uptake.</p><p><strong>Conclusion: </strong>HIV testing uptake among rural men was low. Strengthening awareness programmes on HIV and HIV testing, integrating HIV testing with all other healthcare, strengthening partner accompany and HIV testing during pregnancy and delivery, and providing home-based HIV testing may increase HIV testing uptake.</p>","PeriodicalId":46555,"journal":{"name":"HIV AIDS-Research and Palliative Care","volume":"15 ","pages":"225-234"},"PeriodicalIF":1.5,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d2/9d/hiv-15-225.PMC10164390.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9444799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictors and Factors Associated with Counseling Seeking Behavior Against Intimate Partner Violence Among HIV-Positive Women in Southwestern Uganda 乌干达西南部艾滋病毒阳性妇女寻求亲密伴侣暴力咨询行为的预测因素和相关因素
IF 1.5 Q4 INFECTIOUS DISEASES Pub Date : 2022-06-10 DOI: 10.2147/HIV.S362398
Adella Arishaba, Wilson Kiduuma, Grace Night, I. Arinaitwe, Vallence Niyonzima, V. Mubangizi
Purpose The study intended to establish the proportion of HIV-positive women experiencing IPV and the predictors of counseling-seeking behavior among women living with HIV in Isingiro district. Methods The study was a cross-sectional quantitative study. We conducted the study in April 2021 among 296 HIV-positive women receiving ART services at Rwekubo and Nyamuyanja Health Centre fours. Data were collected using a researcher-administered questionnaire. Consecutively participants were recruited from the ART clinic. SPSS Version 23.0 was used to analyze data. We computed the prevalence of intimate partner violence among the study participants. Logistic regression was performed to identify the associated factors and predictors of counseling-seeking behavior. Results Of the 296 participants interviewed, 66.2% of the HIV-positive women had experienced IPV. Only 40.2% of those who had experienced IPV had received counseling, 35.5% of the participants sought help for IPV from family and friends and 27% sought help from other service providers including the police. A majority (67.2%) of the participants had a primary level of education and over a third (45.9%) of the participants were from monogamous families. The factors associated with seeking care for IPV were education level (p = 0.002), type of family (p = 0.04), physical abuse within one last year (p < 0.001), emotional abuse (p < 0.001), awareness about IPV services (p < 0.001) and availability of counselors (p < 0.001). The predictors of care-seeking for IPV included awareness about IPV services (aOR: 295.6, 95% CI: 54.3–1608.9) and availability of counselors (aOR: 5.3, 95% CI: 1.5–19.2). Conclusion The prevalence of IPV is 66.2%, and proportion of HIV-positive women who seek IPV counseling services is low. The predictors of counseling-seeking behavior were awareness about IPV services and availability of counselors. There is a need to improve awareness about IPV services and provide more counselors to offer help to the IPV victims.
目的本研究旨在了解Isingiro地区HIV阳性妇女经历IPV的比例以及HIV感染妇女寻求咨询行为的预测因素。方法采用横断面定量研究方法。我们于2021年4月对296名在Rwekubo和Nyamuyanja保健中心接受抗逆转录病毒治疗的艾滋病毒阳性妇女进行了研究。数据是通过研究人员填写的问卷收集的。连续从ART诊所招募参与者。采用SPSS Version 23.0进行数据分析。我们计算了研究参与者中亲密伴侣暴力的发生率。采用Logistic回归来确定相关因素和心理咨询行为的预测因素。结果在296名受访妇女中,66.2%的hiv阳性妇女经历过IPV。只有40.2%的受访者曾接受心理辅导,35.5%的受访者曾向家人及朋友求助,27%曾向警方等其他服务提供者求助。大多数(67.2%)的参与者受过初级教育,超过三分之一(45.9%)的参与者来自一夫一妻制家庭。与IPV就诊相关的因素为受教育程度(p = 0.002)、家庭类型(p = 0.04)、过去一年内的身体虐待(p < 0.001)、精神虐待(p < 0.001)、对IPV服务的认识(p < 0.001)和是否有辅导员(p < 0.001)。预测因子包括对IPV服务的了解(aOR: 295.6, 95% CI: 54.3-1608.9)和咨询师的可用性(aOR: 5.3, 95% CI: 1.5-19.2)。结论IPV患病率为66.2%,hiv阳性妇女寻求IPV咨询服务的比例较低。咨询寻求行为的预测因子是对IPV服务的了解和咨询师的可获得性。有必要提高对IPV服务的认识,并提供更多的咨询人员向IPV受害者提供帮助。
{"title":"Predictors and Factors Associated with Counseling Seeking Behavior Against Intimate Partner Violence Among HIV-Positive Women in Southwestern Uganda","authors":"Adella Arishaba, Wilson Kiduuma, Grace Night, I. Arinaitwe, Vallence Niyonzima, V. Mubangizi","doi":"10.2147/HIV.S362398","DOIUrl":"https://doi.org/10.2147/HIV.S362398","url":null,"abstract":"Purpose The study intended to establish the proportion of HIV-positive women experiencing IPV and the predictors of counseling-seeking behavior among women living with HIV in Isingiro district. Methods The study was a cross-sectional quantitative study. We conducted the study in April 2021 among 296 HIV-positive women receiving ART services at Rwekubo and Nyamuyanja Health Centre fours. Data were collected using a researcher-administered questionnaire. Consecutively participants were recruited from the ART clinic. SPSS Version 23.0 was used to analyze data. We computed the prevalence of intimate partner violence among the study participants. Logistic regression was performed to identify the associated factors and predictors of counseling-seeking behavior. Results Of the 296 participants interviewed, 66.2% of the HIV-positive women had experienced IPV. Only 40.2% of those who had experienced IPV had received counseling, 35.5% of the participants sought help for IPV from family and friends and 27% sought help from other service providers including the police. A majority (67.2%) of the participants had a primary level of education and over a third (45.9%) of the participants were from monogamous families. The factors associated with seeking care for IPV were education level (p = 0.002), type of family (p = 0.04), physical abuse within one last year (p < 0.001), emotional abuse (p < 0.001), awareness about IPV services (p < 0.001) and availability of counselors (p < 0.001). The predictors of care-seeking for IPV included awareness about IPV services (aOR: 295.6, 95% CI: 54.3–1608.9) and availability of counselors (aOR: 5.3, 95% CI: 1.5–19.2). Conclusion The prevalence of IPV is 66.2%, and proportion of HIV-positive women who seek IPV counseling services is low. The predictors of counseling-seeking behavior were awareness about IPV services and availability of counselors. There is a need to improve awareness about IPV services and provide more counselors to offer help to the IPV victims.","PeriodicalId":46555,"journal":{"name":"HIV AIDS-Research and Palliative Care","volume":"104 1","pages":"275 - 283"},"PeriodicalIF":1.5,"publicationDate":"2022-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89292714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Factors Affecting Fertility Intention Among People Living with HIV in Kunming, China 影响昆明HIV感染者生育意愿的因素
IF 1.5 Q4 INFECTIOUS DISEASES Pub Date : 2022-05-01 DOI: 10.2147/HIV.S365467
Yingwu Guo, Yingrong Du, S. Lerkiatbundit, Jun Liu, Jing-Xiu Bai, Yongrui Yang, Yin Yang, Aihui Wu, V. Chongsuvivatwong
Background Survival and quality of life of people living with HIV (PLWH) have been improving. Understanding fertility intention among PLWH is critical in helping them accomplish their pregnancy goals while significantly lowering the risk of HIV transmission. The purpose of this study was to identify factors based on the theory of planned behavior (TPB) that may explain fertility intention among PLWH. Methods A survey was conducted in face-to-face interviews based on TPB, and the latent variables were devised and tested for their potential influences on fertility intentions in 487 reproductive-aged PLWH at antiretroviral treatment clinics in Kunming, China. Analysis was mainly based on the structural equation model. Results About 38.4% of the respondents answered that they were likely to have a/another child in the next three years. Our hypothesized factors could explain 53.7% of the total variance of fertility intention. The 20- to 35-year-old group had a higher fertility intention. Perceived partner expectations toward fertility were the strongest predictors of fertility intention followed by beliefs in the support of the two-child policy. In contrast, the three components of attitudes, subjective norm, and perceived behavioral control did not influence fertility intention. Conclusion In this HIV endemic area of China, fertility intended by PLWH is a matter of the couple that is also influenced by the national population fertility policy.
HIV感染者(PLWH)的生存和生活质量不断提高。了解艾滋病毒携带者的生育意愿对于帮助他们实现怀孕目标,同时显著降低艾滋病毒传播风险至关重要。本研究的目的是基于计划行为理论(TPB)来确定可能解释PLWH生育意愿的因素。方法采用面对面访谈法,设计潜在变量,并对昆明地区487家抗逆转录病毒治疗诊所的育龄妇女生育意愿的潜在影响因素进行检验。分析主要基于结构方程模型。结果约38.4%的受访者表示在未来三年内有可能生育一个/另一个孩子。我们假设的因素可以解释生育意愿总方差的53.7%。20- 35岁的女性生育意愿较高。感知伴侣对生育的期望是生育意愿的最强预测因子,其次是对二孩政策支持的信念。相反,态度、主观规范和感知行为控制三个组成部分对生育意愿没有影响。结论在中国HIV流行地区,PLWH的生育意愿是夫妻双方的事情,同时也受到国家人口生育政策的影响。
{"title":"Factors Affecting Fertility Intention Among People Living with HIV in Kunming, China","authors":"Yingwu Guo, Yingrong Du, S. Lerkiatbundit, Jun Liu, Jing-Xiu Bai, Yongrui Yang, Yin Yang, Aihui Wu, V. Chongsuvivatwong","doi":"10.2147/HIV.S365467","DOIUrl":"https://doi.org/10.2147/HIV.S365467","url":null,"abstract":"Background Survival and quality of life of people living with HIV (PLWH) have been improving. Understanding fertility intention among PLWH is critical in helping them accomplish their pregnancy goals while significantly lowering the risk of HIV transmission. The purpose of this study was to identify factors based on the theory of planned behavior (TPB) that may explain fertility intention among PLWH. Methods A survey was conducted in face-to-face interviews based on TPB, and the latent variables were devised and tested for their potential influences on fertility intentions in 487 reproductive-aged PLWH at antiretroviral treatment clinics in Kunming, China. Analysis was mainly based on the structural equation model. Results About 38.4% of the respondents answered that they were likely to have a/another child in the next three years. Our hypothesized factors could explain 53.7% of the total variance of fertility intention. The 20- to 35-year-old group had a higher fertility intention. Perceived partner expectations toward fertility were the strongest predictors of fertility intention followed by beliefs in the support of the two-child policy. In contrast, the three components of attitudes, subjective norm, and perceived behavioral control did not influence fertility intention. Conclusion In this HIV endemic area of China, fertility intended by PLWH is a matter of the couple that is also influenced by the national population fertility policy.","PeriodicalId":46555,"journal":{"name":"HIV AIDS-Research and Palliative Care","volume":"719 1","pages":"265 - 273"},"PeriodicalIF":1.5,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74766423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Experiences of HIV Positive Serostatus Disclosure to Sexual Partner Among Individuals in Discordant Couples in Mbarara City, Southwestern Uganda 乌干达西南部姆巴拉拉市不和谐夫妇中向性伴侣披露艾滋病毒阳性血清状况的经历
IF 1.5 Q4 INFECTIOUS DISEASES Pub Date : 2022-05-01 DOI: 10.2147/HIV.S361898
Humphrey Atwijukiire, Gladys Nakidde, Anne T. Otwine, J. Kabami
Purpose Disclosure of HIV status is key in HIV management. Despite many studies on serostatus disclosure, there is a gap in experiences regarding HIV status disclosure among discordant couples. The current study addressed this research gap, and explored the lived experiences of serostatus disclosure among discordant couples in Mbarara City, South Western Uganda. Participants and Methods We conducted 12 in-depth interviews with the help of a translated interview guide, and they were audio recorded. Participants were purposively enrolled in the study, which employed a phenomenological qualitative design. The study was conducted at three public health facilities in Mbarara City. The data was analyzed using thematic content analysis. Approval for this research was obtained from the Mbarara University Research Ethics Committee (MUST-REC) and administrative clearance from the city clerk of Mbarara City. Results The mean age of the participants was 38 years old, ranging from 20 to 67 years. An equal number of males (six) and females participated in this study. Most of them had at least secondary level education, and only three had primary education. Half of the participants disclosed their serostatus to partners immediately after testing HIV positive. Key emerging themes as experienced benefits of HIV serostatus disclosure included: 1) social support and care; 2) decisions regarding health, fertility, and child bearing; 3) sharing information on HIV prevention and protection measures; 4) positive living; and 5) ease of HIV serostatus disclosure. The challenges associated with serostatus disclosure were summarized as one theme: misunderstandings in the families of the discordant couples. Conclusion Socially, psychologically and financially HIV positive individuals have benefited from their negative partners. Healthwise, they have been supported, and cared for after disclosing their positive status, but some have faced challenges, such as family misunderstandings. Couple HIV counseling and testing by a trained health worker is beneficial in HIV care and could mitigate the challenges related HIV serostatus disclosure.
目的披露艾滋病毒感染状况是艾滋病毒管理的关键。尽管有许多关于血清状态披露的研究,但在不一致的夫妇中,关于艾滋病毒状态披露的经验存在差距。目前的研究解决了这一研究差距,并探索了乌干达西南部姆巴拉拉市不和谐夫妇中血清状态披露的生活经历。在翻译的访谈指南的帮助下,我们进行了12次深度访谈,并进行了录音。研究采用现象学定性设计,参与者被有意纳入研究。这项研究是在姆巴拉拉市的三个公共卫生设施进行的。采用主题内容分析法对数据进行分析。这项研究获得了姆巴拉拉大学研究伦理委员会(MUST-REC)的批准,并获得了姆巴拉拉市职员的行政许可。结果参与者平均年龄38岁,年龄从20岁到67岁不等。参与这项研究的男性和女性人数相同(6人)。他们中的大多数人至少受过中等教育,只有三人受过初等教育。一半的参与者在艾滋病毒检测呈阳性后立即向伴侣透露了他们的血清状况。艾滋病毒血清状况披露所带来的主要益处包括:1)社会支持和护理;2)关于健康、生育和生育的决定;3)分享艾滋病预防和保护措施信息;4)积极生活;5)易于艾滋病毒血清状况披露。与血清状态披露相关的挑战被总结为一个主题:不和谐夫妻家庭中的误解。结论艾滋病毒阳性个体在社会、心理和经济上受益于其阴性伴侣。在健康方面,他们在公开自己的阳性身份后得到了支持和照顾,但有些人面临挑战,例如家庭误解。由训练有素的卫生工作者进行的夫妻艾滋病毒咨询和检测有利于艾滋病毒护理,并可减轻与艾滋病毒血清状况披露有关的挑战。
{"title":"Experiences of HIV Positive Serostatus Disclosure to Sexual Partner Among Individuals in Discordant Couples in Mbarara City, Southwestern Uganda","authors":"Humphrey Atwijukiire, Gladys Nakidde, Anne T. Otwine, J. Kabami","doi":"10.2147/HIV.S361898","DOIUrl":"https://doi.org/10.2147/HIV.S361898","url":null,"abstract":"Purpose Disclosure of HIV status is key in HIV management. Despite many studies on serostatus disclosure, there is a gap in experiences regarding HIV status disclosure among discordant couples. The current study addressed this research gap, and explored the lived experiences of serostatus disclosure among discordant couples in Mbarara City, South Western Uganda. Participants and Methods We conducted 12 in-depth interviews with the help of a translated interview guide, and they were audio recorded. Participants were purposively enrolled in the study, which employed a phenomenological qualitative design. The study was conducted at three public health facilities in Mbarara City. The data was analyzed using thematic content analysis. Approval for this research was obtained from the Mbarara University Research Ethics Committee (MUST-REC) and administrative clearance from the city clerk of Mbarara City. Results The mean age of the participants was 38 years old, ranging from 20 to 67 years. An equal number of males (six) and females participated in this study. Most of them had at least secondary level education, and only three had primary education. Half of the participants disclosed their serostatus to partners immediately after testing HIV positive. Key emerging themes as experienced benefits of HIV serostatus disclosure included: 1) social support and care; 2) decisions regarding health, fertility, and child bearing; 3) sharing information on HIV prevention and protection measures; 4) positive living; and 5) ease of HIV serostatus disclosure. The challenges associated with serostatus disclosure were summarized as one theme: misunderstandings in the families of the discordant couples. Conclusion Socially, psychologically and financially HIV positive individuals have benefited from their negative partners. Healthwise, they have been supported, and cared for after disclosing their positive status, but some have faced challenges, such as family misunderstandings. Couple HIV counseling and testing by a trained health worker is beneficial in HIV care and could mitigate the challenges related HIV serostatus disclosure.","PeriodicalId":46555,"journal":{"name":"HIV AIDS-Research and Palliative Care","volume":"106 1","pages":"231 - 242"},"PeriodicalIF":1.5,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80728680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Post-Traumatic Stress Disorder and Coping Strategies Among People with HIV in Lira District, Uganda: A Cross-Sectional Study 乌干达里拉地区艾滋病毒感染者的创伤后应激障碍和应对策略:一项横断面研究
IF 1.5 Q4 INFECTIOUS DISEASES Pub Date : 2022-05-01 DOI: 10.2147/HIV.S358575
Benedict Arebo, Gracious Faith Ewach, Jacob Omara, Pamella Oyella, Ruth Aciro Lucky, Amir Kabunga
Background Post-traumatic stress disorder (PTSD) is the most commonly reported mental health consequence following traumatic events. However, little is known about how people with HIV cope with the PTSD burden in Lira city, northern Uganda. Materials and Methods This study was carried out in Lira District Health Centre IVs from February 10, 2022, to March 10, 2022. A facility-based cross-sectional study was employed among 390 people with HIV attending Lira Health Centre IVs. A consecutive sampling technique was used to select the sample size. Questionnaires were used to collect data. A binary logistic regression model was fitted to identify factors associated with independent variables, and AOR was employed to estimate the strength of association between independent and dependent variables. Results Results show that the estimated prevalence of PTSD was 254 (65.1%) and was higher among the females 191 (75.2%), those with no formal education 143 (56.3%), aged 40 years and above 121 (47.6%), and married 127 (50.0%). Results indicate that male respondents had a 51% reduced odds of developing PTSD burden compared to female respondents (AOR: 0.49; 95% CI: 0.30–0.81; P = 0.005). Individuals who did not use planning activities as a coping strategy had more than 2-fold increased odds of experiencing PTSD compared to those who planned activities (AOR: 2.43; 1.26–4.70; P = 0.008). Participants who did not have emotional support had close to 3-fold increased chances of developing PTSD compared to those who had emotional support (AOR: 2.94; 1.74–4.98; P ≤ 0.001). Participants who indicated they were not taking recourse to spirituality had more than 4-fold increased odds of experiencing PTSD compared to those who had spirituality (AOR: 4.40; 1.83–10.46; P = 0.001). Conclusion A considerable burden of PTSD among HIV clients attending health centre IVs in Lira District was notably higher and was associated with gender, planning activities, emotional support and spirituality. Early screening of PTSD among HIV clients is needed to alleviate the burden. There is also a need to include PTSD treatment services in the treatment programme of HIV care services in health centre IVs in Lira District.
背景创伤后应激障碍(PTSD)是创伤事件后最常见的心理健康后果。然而,在乌干达北部的里拉市,人们对艾滋病毒感染者如何应对创伤后应激障碍负担知之甚少。材料与方法本研究于2022年2月10日至2022年3月10日在里拉区卫生中心iv进行。对在里拉第四保健中心就诊的390名艾滋病毒感染者进行了一项以设施为基础的横断面研究。采用连续抽样技术选择样本量。通过问卷调查收集数据。拟合二元logistic回归模型识别与自变量相关的因素,采用AOR估计自变量与因变量之间的关联强度。结果创伤后应激障碍估计患病率为254例(65.1%),其中女性191例(75.2%),未受过正规教育者143例(56.3%),40岁及以上人群121例(47.6%),已婚人群127例(50.0%)。结果显示,与女性受访者相比,男性受访者患PTSD负担的几率降低了51% (AOR: 0.49;95% ci: 0.30-0.81;P = 0.005)。与计划活动的个体相比,不将计划活动作为应对策略的个体经历PTSD的几率增加了2倍以上(AOR: 2.43;1.26 - -4.70;P = 0.008)。与有情感支持的参与者相比,没有情感支持的参与者患PTSD的几率增加了近3倍(AOR: 2.94;1.74 - -4.98;P≤0.001)。那些表示他们没有求助于精神疗法的参与者与那些有精神疗法的人相比,患PTSD的几率增加了4倍多(AOR: 4.40;1.83 - -10.46;P = 0.001)。结论Lira区第四保健中心艾滋病患者创伤后应激障碍负担较高,且与性别、计划活动、情感支持和精神相关。需要对艾滋病毒患者进行创伤后应激障碍的早期筛查,以减轻负担。还需要将创伤后应激障碍治疗服务纳入里拉区第四保健中心艾滋病毒护理服务的治疗方案。
{"title":"Post-Traumatic Stress Disorder and Coping Strategies Among People with HIV in Lira District, Uganda: A Cross-Sectional Study","authors":"Benedict Arebo, Gracious Faith Ewach, Jacob Omara, Pamella Oyella, Ruth Aciro Lucky, Amir Kabunga","doi":"10.2147/HIV.S358575","DOIUrl":"https://doi.org/10.2147/HIV.S358575","url":null,"abstract":"Background Post-traumatic stress disorder (PTSD) is the most commonly reported mental health consequence following traumatic events. However, little is known about how people with HIV cope with the PTSD burden in Lira city, northern Uganda. Materials and Methods This study was carried out in Lira District Health Centre IVs from February 10, 2022, to March 10, 2022. A facility-based cross-sectional study was employed among 390 people with HIV attending Lira Health Centre IVs. A consecutive sampling technique was used to select the sample size. Questionnaires were used to collect data. A binary logistic regression model was fitted to identify factors associated with independent variables, and AOR was employed to estimate the strength of association between independent and dependent variables. Results Results show that the estimated prevalence of PTSD was 254 (65.1%) and was higher among the females 191 (75.2%), those with no formal education 143 (56.3%), aged 40 years and above 121 (47.6%), and married 127 (50.0%). Results indicate that male respondents had a 51% reduced odds of developing PTSD burden compared to female respondents (AOR: 0.49; 95% CI: 0.30–0.81; P = 0.005). Individuals who did not use planning activities as a coping strategy had more than 2-fold increased odds of experiencing PTSD compared to those who planned activities (AOR: 2.43; 1.26–4.70; P = 0.008). Participants who did not have emotional support had close to 3-fold increased chances of developing PTSD compared to those who had emotional support (AOR: 2.94; 1.74–4.98; P ≤ 0.001). Participants who indicated they were not taking recourse to spirituality had more than 4-fold increased odds of experiencing PTSD compared to those who had spirituality (AOR: 4.40; 1.83–10.46; P = 0.001). Conclusion A considerable burden of PTSD among HIV clients attending health centre IVs in Lira District was notably higher and was associated with gender, planning activities, emotional support and spirituality. Early screening of PTSD among HIV clients is needed to alleviate the burden. There is also a need to include PTSD treatment services in the treatment programme of HIV care services in health centre IVs in Lira District.","PeriodicalId":46555,"journal":{"name":"HIV AIDS-Research and Palliative Care","volume":"144 1","pages":"255 - 264"},"PeriodicalIF":1.5,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89010855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Experiences of Antiretroviral Therapy Initiation Among HIV-Positive Adults in Ethiopia: A Descriptive Phenomenological Design 在埃塞俄比亚hiv阳性成人中开始抗逆转录病毒治疗的经验:描述现象学设计
IF 1.5 Q4 INFECTIOUS DISEASES Pub Date : 2022-05-01 DOI: 10.2147/HIV.S361913
E. Tefera, A. Mavhandu-Mudzusi
Purpose The aim of the study was to explore and describe the lived experiences of HIV-positive adults on antiretroviral therapy (ART) initiation in West Shoa Zone, Ethiopia. Materials and Methods A descriptive phenomenological design was utilized in the study to gain insight into participants’ lived experiences regarding ART initiation in West Shoa Zone, Ethiopia. Data were collected through semi-structured in-depth interviews and analyzed by means of thematic analysis. Results The study found that spousal influence, denial of status, inconsistent ART initiation protocol, poverty, fear of side effects, religion and shortages of staff were factors that caused delayed ART initiation. A low CD4 count, the development of opportunistic infections and the prevention of future illness were factors that promoted ART initiation. Conclusion This study provides an overview of experiences of adults living with HIV regarding ART initiation. The study emphasizes the need to improve adequate provision of resources to address issues related to finance, human capital, guidelines and inequity to enhance early ART initiation among HIV-positive adults in West Shoa Zone. The study findings have implications for policy implementation, ART service delivery, and the enhancement of prompt ART initiation in the study settings.
目的:本研究的目的是探索和描述埃塞俄比亚西绍阿地区艾滋病毒阳性成人开始抗逆转录病毒治疗(ART)的生活经历。材料和方法本研究采用描述性现象学设计,以深入了解埃塞俄比亚西绍阿地区参与者关于ART启动的生活经历。采用半结构化深度访谈法收集数据,采用专题分析方法进行分析。结果研究发现,配偶影响、身份否认、启动抗逆转录病毒治疗方案不一致、贫困、害怕副作用、宗教信仰和人员短缺是导致延迟启动抗逆转录病毒治疗的因素。CD4细胞计数低、机会性感染的发生和对未来疾病的预防是促进抗逆转录病毒治疗开始的因素。结论:本研究概述了成人艾滋病毒感染者开始抗逆转录病毒治疗的经历。该研究强调有必要改善充足的资源供应,以解决与资金、人力资本、指导方针和不平等有关的问题,以加强西Shoa区艾滋病毒阳性成年人的早期抗逆转录病毒治疗。研究结果对政策实施、提供抗逆转录病毒治疗服务以及在研究环境中加强及时启动抗逆转录病毒治疗具有重要意义。
{"title":"Experiences of Antiretroviral Therapy Initiation Among HIV-Positive Adults in Ethiopia: A Descriptive Phenomenological Design","authors":"E. Tefera, A. Mavhandu-Mudzusi","doi":"10.2147/HIV.S361913","DOIUrl":"https://doi.org/10.2147/HIV.S361913","url":null,"abstract":"Purpose The aim of the study was to explore and describe the lived experiences of HIV-positive adults on antiretroviral therapy (ART) initiation in West Shoa Zone, Ethiopia. Materials and Methods A descriptive phenomenological design was utilized in the study to gain insight into participants’ lived experiences regarding ART initiation in West Shoa Zone, Ethiopia. Data were collected through semi-structured in-depth interviews and analyzed by means of thematic analysis. Results The study found that spousal influence, denial of status, inconsistent ART initiation protocol, poverty, fear of side effects, religion and shortages of staff were factors that caused delayed ART initiation. A low CD4 count, the development of opportunistic infections and the prevention of future illness were factors that promoted ART initiation. Conclusion This study provides an overview of experiences of adults living with HIV regarding ART initiation. The study emphasizes the need to improve adequate provision of resources to address issues related to finance, human capital, guidelines and inequity to enhance early ART initiation among HIV-positive adults in West Shoa Zone. The study findings have implications for policy implementation, ART service delivery, and the enhancement of prompt ART initiation in the study settings.","PeriodicalId":46555,"journal":{"name":"HIV AIDS-Research and Palliative Care","volume":"24 1","pages":"243 - 254"},"PeriodicalIF":1.5,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79286144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The Incidence of Adverse Drug Reaction Among Adult Patients on Antiretroviral Therapy in Ethiopia: Frailty Model 埃塞俄比亚接受抗逆转录病毒治疗的成人患者药物不良反应发生率:脆弱性模型
IF 1.5 Q4 INFECTIOUS DISEASES Pub Date : 2022-04-01 DOI: 10.2147/HIV.S358351
M. Menza
Introduction Adverse drug reactions are a major global public health concern and an important cause of hospitalization, discontinuation of the drug, morbidity and mortality. Even though the prevalence in Ethiopia was declining at a moderate rate, still, far too many people are suffering and dying unnecessarily due to adverse drug reactions. Objective The aim of this study was to determine the incidence of adverse drug reaction and its predictors among adult patients on antiretroviral therapy. Methods A retrospective follow-up study was conducted at Nigist Elleni Mohamed Memorial Comprehensive Specialized Hospital, Southern Ethiopia. Data were extracted from patients’ medical records. The Weibull model with gamma frailty distribution was fitted. Statistical significance was employed at a 5% level of significance and adjusted hazard ratio with 95% confidence interval was used. Results Out of the total 376 participants followed for 1988 person years of observations, 96 developed adverse reaction with the incidence rate of 4.820/100 per (95%CI: 4.102–5.317). The univariate frailty was statistically significant (theta=0.306, 95%CI: 0.102–0.521). Baseline CD4 count (AHR: 0.997, 95%CI: 0996–0.998), fair adherence (AHR: 2.358, 95%CI: 1.133–4.904), poor adherence (AHR: 3.069, 95%CI: 1.730–5.445), HIV/TB coinfection (AHR: 2.069, 95%CI: 1.115–3.843), WHO stage II (3.128, 95%CI: 1.414–6.916), WHO stage III (AHR: 2.709, 95%CI: 1.048–7.025) and WHO stage IV (1.516, 10.352) were associated with the incidence adverse reaction. Conclusion Most of the ADR cases occurred within two years after initiation of ART. Advanced clinical stage, TB coinfection, CD4 count, and poor adherence were predictors of ADRs. Continuous counseling for clients in advanced clinical stage and patients with TB coinfection need to get close follow-up to prevent the associated ADRs by the concerned parties.
药物不良反应是一个主要的全球公共卫生问题,也是住院、停药、发病率和死亡率的重要原因。尽管埃塞俄比亚的流行率正在以适度的速度下降,但仍有太多的人因药物不良反应而遭受不必要的痛苦和死亡。目的了解成人抗逆转录病毒治疗患者药物不良反应的发生率及其预测因素。方法回顾性随访研究在埃塞俄比亚南部Nigist Elleni Mohamed纪念综合专科医院进行。数据从患者的医疗记录中提取。拟合了具有脆性分布的Weibull模型。统计学意义采用5%显著性水平,校正风险比采用95%置信区间。结果在随访的376名参与者中,有96名出现不良反应,发生率为4.820/100 /人(95%CI: 4.102-5.317)。单因素脆弱性有统计学意义(θ =0.306, 95%CI: 0.102 ~ 0.521)。基线CD4计数(AHR: 0.997, 95%CI: 0996-0.998)、一般依从性(AHR: 2.358, 95%CI: 1.133-4.904)、不良依从性(AHR: 3.069, 95%CI: 1.330 - 5.445)、HIV/TB合并感染(AHR: 2.069, 95%CI: 1.115-3.843)、WHO II期(3.128,95%CI: 1.414-6.916)、WHO III期(AHR: 2.709, 95%CI: 1.048-7.025)、WHO IV期(1.516,10.352)与不良反应发生率相关。结论不良反应多发生在抗逆转录病毒治疗开始后2年内。晚期临床阶段、结核病合并感染、CD4计数和不良依从性是不良反应的预测因素。对临床晚期患者和结核合并感染患者进行持续咨询,需要密切随访,防止相关方发生相关不良反应。
{"title":"The Incidence of Adverse Drug Reaction Among Adult Patients on Antiretroviral Therapy in Ethiopia: Frailty Model","authors":"M. Menza","doi":"10.2147/HIV.S358351","DOIUrl":"https://doi.org/10.2147/HIV.S358351","url":null,"abstract":"Introduction Adverse drug reactions are a major global public health concern and an important cause of hospitalization, discontinuation of the drug, morbidity and mortality. Even though the prevalence in Ethiopia was declining at a moderate rate, still, far too many people are suffering and dying unnecessarily due to adverse drug reactions. Objective The aim of this study was to determine the incidence of adverse drug reaction and its predictors among adult patients on antiretroviral therapy. Methods A retrospective follow-up study was conducted at Nigist Elleni Mohamed Memorial Comprehensive Specialized Hospital, Southern Ethiopia. Data were extracted from patients’ medical records. The Weibull model with gamma frailty distribution was fitted. Statistical significance was employed at a 5% level of significance and adjusted hazard ratio with 95% confidence interval was used. Results Out of the total 376 participants followed for 1988 person years of observations, 96 developed adverse reaction with the incidence rate of 4.820/100 per (95%CI: 4.102–5.317). The univariate frailty was statistically significant (theta=0.306, 95%CI: 0.102–0.521). Baseline CD4 count (AHR: 0.997, 95%CI: 0996–0.998), fair adherence (AHR: 2.358, 95%CI: 1.133–4.904), poor adherence (AHR: 3.069, 95%CI: 1.730–5.445), HIV/TB coinfection (AHR: 2.069, 95%CI: 1.115–3.843), WHO stage II (3.128, 95%CI: 1.414–6.916), WHO stage III (AHR: 2.709, 95%CI: 1.048–7.025) and WHO stage IV (1.516, 10.352) were associated with the incidence adverse reaction. Conclusion Most of the ADR cases occurred within two years after initiation of ART. Advanced clinical stage, TB coinfection, CD4 count, and poor adherence were predictors of ADRs. Continuous counseling for clients in advanced clinical stage and patients with TB coinfection need to get close follow-up to prevent the associated ADRs by the concerned parties.","PeriodicalId":46555,"journal":{"name":"HIV AIDS-Research and Palliative Care","volume":"27 1","pages":"155 - 165"},"PeriodicalIF":1.5,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90480519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
期刊
HIV AIDS-Research and Palliative Care
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1