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A systematic review of robot-assisted partial nephrectomy outcomes for advanced indications: Large tumors (cT2-T3), solitary kidney, completely endophytic, hilar, recurrent, and multiple renal tumors 系统回顾机器人辅助部分肾切除术治疗晚期适应症的结果:大肿瘤(cT2-T3)、孤立肾、完全内生、肾门癌、复发性和多发性肾肿瘤
IF 2.6 3区 医学 Q2 UROLOGY & NEPHROLOGY Pub Date : 2023-10-01 DOI: 10.1016/j.ajur.2023.06.001
Savio Domenico Pandolfo , Clara Cerrato , Zhenjie Wu , Antonio Franco , Francesco Del Giudice , Alessandro Sciarra , Paolo Verze , Giuseppe Lucarelli , Ciro Imbimbo , Sisto Perdonà , Edward E. Cherullo , Francesco Porpiglia , Ithaar H. Derweesh , Riccardo Autorino

Objective

Robot-assisted partial nephrectomy (RAPN) has become widely used for treatment of renal cell carcinoma and it is expanding in the field of complex renal masses. The aim of this systematic review was to analyze outcomes of RAPN for completely endophytic renal masses, large tumors (cT2-T3), renal cell carcinoma in solitary kidney, recurrent tumors, completely endophytic and hilar masses, and simultaneous and multiple tumors.

Methods

A comprehensive search in the PubMed, Scopus, Web of Science, and Cochrane Central Register of Controlled Trials databases was performed in December 2022 for English language papers. The primary endpoint was to evaluate the role of RAPN in the setting of each category of complex renal masses considered. The secondary endpoint was to evaluate the surgical and functional outcomes.

Results

After screening 1250 records, 43 full-text manuscripts were selected, comprising over 8500 patients. Twelve and thirteen studies reported data for endophytic and hilar renal masses, respectively. Five and three studies reported outcomes for cT2-T3 and solitary kidney patients, respectively. Four studies focused on redo-RAPN for recurrent tumors. Two studies investigated simultaneous bilateral renal masses and five reports focused on multiple tumor excision in ipsilateral kidney.

Conclusion

Over the past decade, evidence supporting the use of RAPN for the most challenging nephron-sparing surgery indications has continuously grown. Although limitations remain including study design and lack of detailed long-term functional and oncological outcomes, the adoption of RAPN for the included advanced indications is associated with favorable surgical outcomes with good preservation of renal function without compromising the oncological result. Certainly, a higher likelihood of complication might be expected when facing extremely challenging cases. However, none of these indications should be considered per se an exclusion criterion for performing RAPN. Ultimately, a risk-adapted approach should be employed.

目的机器人辅助肾部分切除术(RAPN)已广泛应用于肾细胞癌的治疗,并在复杂肾肿块的治疗领域不断扩大。本系统综述的目的是分析RAPN治疗完全内生肾肿块、大肿瘤(cT2-T3)、孤立肾肾细胞癌、复发性肿瘤、完全内生和肝门肿块以及同时发生和多发肿瘤的结果。方法于2022年12月在PubMed、Scopus、Web of Science和Cochrane对照试验中央注册数据库中全面搜索英文论文。主要终点是评估RAPN在所考虑的每一类复杂肾脏肿块中的作用。次要终点是评估手术和功能结果。结果筛选出1250篇文献,筛选出43篇全文稿件,共8500余名患者。12项和13项研究分别报告了内生和肝门肾块的数据。分别有五项和三项研究报告了cT2-T3和孤立肾患者的结果。四项研究集中于复发性肿瘤的重做RAPN。两项研究调查了同时发生的双侧肾脏肿块,五份报告集中于同侧肾脏的多发肿瘤切除。结论在过去的十年里,支持RAPN用于最具挑战性的保留肾单位手术适应症的证据不断增加。尽管仍存在局限性,包括研究设计和缺乏详细的长期功能和肿瘤学结果,但采用RAPN作为纳入的晚期适应症与良好的手术结果相关,在不影响肿瘤学结果的情况下,肾功能得到良好保存。当然,当面对极具挑战性的病例时,并发症的可能性可能会更高。然而,这些适应症本身都不应被视为进行RAPN的排除标准。最终,应采用适应风险的方法。
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引用次数: 0
Double-face urethroplasty in patients with obliterative bulbar strictures post-transurethral resection of the prostate mid-term outcomes in high-volume referral center 经尿道前列腺切除术后隐匿性球狭窄患者的双面尿道成形术中期疗效分析
IF 2.6 3区 医学 Q2 UROLOGY & NEPHROLOGY Pub Date : 2023-10-01 DOI: 10.1016/j.ajur.2021.11.001
Pankaj M. Joshi , Manuel Hevia , Yatam Lakshmi Sreeranga , Marco Bandini , Amey Patil , Shreyas Bhadranavar , Vipin Sharma , Sandeep Bafna , Sanjay B. Kulkarni

Objective

Incidences of post-transurethral resection of the prostate (post-TURP) strictures are between 2.2% and 9.8%. Stricture commonly occurs within the first 6 months. Our objective was to assess the outcomes of patients with obliterative strictures post-TURP that underwent a double-face urethroplasty.

Methods

This is a single-center prospective study of 17 patients with obliterative proximal bulbar stricture post-TURP who underwent double-face graft urethroplasty by two surgeons between January 2014 and January 2020. We defined post-TURP obliterative strictures as those patients who presented with complete or almost complete obstruction of the urethral lumen and who have had a history of acute urine retention. We have excluded patients with bladder neck contracture. Primary outcome was treatment success, defined as the no need for further treatments. Secondary outcome was post-urethroplasty continent rate.

Results

Seventeen patients were included in the study with median age of 66 (interquartile range 40–77) years; median time of follow-up was 24 (interquartile range 12–84) months; median stricture length was 4 (interquartile range 2–6) cm. Of the 17 patients, 15 (88.2%) were successful. All patients were continent after urethroplasty.

Conclusion

With mid-term follow-up, treatment of obliterative proximal bulbar strictures with double-face buccal mucosa graft is a safe and effective procedure. Obliterative proximal bulbar strictures merit double-face urethroplasty with high-rate success and functional outcomes.

目的经尿道前列腺电切术后狭窄的发生率在2.2%至9.8%之间,狭窄通常发生在前6个月。我们的目的是评估TURP术后接受双面尿道成形术的闭塞性狭窄患者的预后。方法这是一项单中心前瞻性研究,对2014年1月至2020年1月期间由两名外科医生进行双面移植物尿道成形术的17名TURP后闭塞性近端球根狭窄患者进行了研究。我们将TURP术后闭塞性狭窄定义为尿道腔完全或几乎完全阻塞且有急性尿潴留史的患者。我们排除了膀胱颈挛缩症患者。主要结果是治疗成功,定义为无需进一步治疗。次要结果是尿道成形术后的大陆率。结果17名患者被纳入研究,中位年龄为66岁(四分位间距40-77);中位随访时间为24个月(四分位间距12-84);狭窄的中位长度为4(四分位间距2-6)cm。在17例患者中,15例(88.2%)成功。所有患者在尿道成形术后均为大陆。结论经中期随访,双面颊粘膜移植治疗闭塞性近端延髓狭窄是一种安全有效的方法。闭塞性近端延髓狭窄值得采用双面尿道成形术,成功率高,功能效果好。
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引用次数: 0
Prospective observational study on the prognosis of ureteral lesions caused by impacted stones via dual-energy spectral computed tomography 双能谱计算机断层扫描对嵌顿结石所致输尿管病变预后的前瞻性观察研究
IF 2.6 3区 医学 Q2 UROLOGY & NEPHROLOGY Pub Date : 2023-10-01 DOI: 10.1016/j.ajur.2022.05.007
Junjie Wang , Ximing Wang , Haozhou Zhong , Wengui Xie , Qilin Xi

Objective

Ureteral lesions caused by impacted ureteral stones are likely to result in postoperative ureteral stricture. On this basis, the study aimed to investigate if dual-energy spectral computed tomography can predict ureteral hardening caused by impacted stones and to explore the relationship between different types of ureteral lesions and the risk of ureteral stricture.

Methods

This prospective study collected data of 93 patients with impacted stones from hospital automation system during January 2018 to October 2019. They underwent an abdominal scan on a dual-energy spectral computed tomography. During surgery, the operator used ureteroscopy to identify ureteral lesions, which were classified into four categories: edema, polyps, pallor, and hardening. Seven months later, 90 patients were reviewed for the degree of hydronephrosis.

Results

Endoscopic observations revealed 38 (41%) cases of ureteral edema, 20 (22%) cases of polyps, 13 (14%) cases of pallor, and 22 (24%) cases of hardening. There were significant differences in hydronephrosis, the period of impaction, the calcium concentration of the ureter, and the slope of the spectral Hounsfield unit curve between the four groups. After that, we evaluated the factors associated with ureteral hardening and found that the calcium concentration of the ureter and hydronephrosis remained independent predictors of ureteral hardening. Receiver operating characteristic curve analysis showed that 5.3 mg/cm³ calcium concentration of the ureter is an optimal cut-off value to predict ureteral hardening. The result of follow-up showed that 80 patients had complete remission of hydronephrosis, with a complete remission rate of 61.9% (13/21) in the hardening group and 97.1% (67/69) in the non-hardening group (p<0.001).

Conclusion

Calcium concentration of the ureter is an independent predictor of ureteral hardening. Patients with ureteral hardening have more severe hydronephrosis after ureteroscopic lithotripsy. When the calcium concentration of the ureter is less than 5.3 mg/cm³, ureteral lesions should be actively treated.

目的:阻生输尿管结石引起的输尿管病变易导致输尿管术后狭窄。在此基础上,本研究旨在探讨双能谱计算机断层扫描是否可以预测嵌套结石引起的输尿管硬化,并探讨不同类型输尿管病变与输尿管狭窄风险的关系。方法本前瞻性研究收集了2018年1月至2019年10月医院自动化系统中93例埋伏结石患者的数据。他们接受了腹部双能谱计算机断层扫描。手术中,操作者使用输尿管镜检查输尿管病变,将输尿管病变分为水肿、息肉、苍白、硬化四类。7个月后,对90例患者进行肾积水程度检查。结果镜下输尿管水肿38例(41%),息肉20例(22%),苍白13例(14%),硬化22例(24%)。四组患者在肾积水、嵌塞时间、输尿管钙浓度、光谱Hounsfield单位曲线斜率等方面均有显著差异。之后,我们评估了与输尿管硬化相关的因素,发现输尿管钙浓度和肾积水仍然是输尿管硬化的独立预测因素。患者工作特征曲线分析显示,输尿管钙浓度5.3 mg/cm³是预测输尿管硬化的最佳临界值。随访结果显示,80例患者肾积水完全缓解,硬化组完全缓解率为61.9%(13/21),非硬化组完全缓解率为97.1% (67/69)(p<0.001)。结论输尿管钙浓度是输尿管硬化的独立预测指标。输尿管镜碎石术后输尿管硬化患者肾积水更为严重。当输尿管钙浓度小于5.3 mg/cm³时,应积极治疗输尿管病变。
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引用次数: 0
Intermediate-term oncological and functional outcomes in prostate cancer patients treated with perineal robot-assisted radical prostatectomy: A single center analysis 会阴机器人辅助根治性前列腺切除术治疗前列腺癌患者的中期肿瘤和功能预后:单中心分析
IF 2.6 3区 医学 Q2 UROLOGY & NEPHROLOGY Pub Date : 2023-10-01 DOI: 10.1016/j.ajur.2023.05.005
Umberto Carbonara, Giuseppe Lippolis, Luciano Rella, Paolo Minafra, Giuseppe Guglielmi, Antonio Vitarelli, Giuseppe Lucarelli, Pasquale Ditonno

Objective

In the last 10 years, robotic platforms allowed to resume of some alternative surgical approaches, including perineal robot-assisted radical prostatectomy (p-RARP). Herein, we present in detail the oncological and functional outcomes of patients who underwent p-RARP with a median follow-up of 30 months.

Methods

Patients presenting low- or intermediate-risk prostate cancer and prostate volume up to 60 mL who underwent p-RARP between November 2018 and November 2022 were selected. Baseline, intraoperative, pathological, and postoperative data were collected and then analyzed.

Results

Thirty-seven p-RARP cases were included. Such patients presented mean age of 62 years and a mean Charlson comorbidity index of 4. Body mass index of ≥25 kg/m2 was reported by 24 (64.9%) patients, as well as 7 (18.9%) patients reported a past surgical history. Mean prostate volume and median prostate-specific antigen were 41 mL and 6.2 ng/mL, respectively. The median operative time was 242 min. The positive surgical margin rate was 45.9%. In terms of postoperative complications, 10 patients reported complications with any grade; however, a single case (2.7%) of major (Clavien-Dindo grade ≥3) complication was observed. No patient with biochemical recurrence or distant metastasis was reported at 2 years of follow-up. Recovery of continence rates were 67.6%, 75.7%, and 92.9%, at 6 months, 12 months, and 24 months after surgery, respectively.

Conclusion

p-RARP is a challenging but safe minimally invasive approach for selected patients with prostate cancer suitable for radical prostatectomy, showing outstanding functional recovery. Despite positive surgical margin rates being relatively high, no cases of biochemical recurrence or distant metastasis were reported after a median follow-up of 30 months.

目的在过去的10年里,机器人平台允许恢复一些替代手术方法,包括会阴机器人辅助前列腺根治术(p-RARP)。在此,我们详细介绍了接受p-RARP的患者的肿瘤学和功能结果,这些患者的中位随访时间为30个月。方法选择在2018年11月至2022年11月期间接受p-RARP的患有低或中盘前列腺癌症且前列腺体积达60mL的患者。收集基线、术中、病理和术后数据,然后进行分析。结果包括37例p-RARP病例。这些患者的平均年龄为62岁,平均Charlson合并症指数为4。24名(64.9%)患者报告体重指数≥25 kg/m2,7名(18.9%)患者报告既往手术史。平均前列腺体积和前列腺特异性抗原中位数分别为41 mL和6.2 ng/mL。中位手术时间为242分钟。手术切缘阳性率为45.9%。在术后并发症方面,10例患者报告了任何级别的并发症;然而,观察到一例(2.7%)严重(Clavien-Dindo分级≥3)并发症。随访2年时,未报告有生化复发或远处转移的患者。术后6个月、12个月和24个月的失禁恢复率分别为67.6%、75.7%和92.9%。结论p-RARP是一种具有挑战性但安全的微创方法,可用于选择适合于彻底前列腺切除术的癌症前列腺患者,显示出良好的功能恢复。尽管阳性手术切缘率相对较高,但在中位随访30个月后,没有生化复发或远处转移的病例报告。
{"title":"Intermediate-term oncological and functional outcomes in prostate cancer patients treated with perineal robot-assisted radical prostatectomy: A single center analysis","authors":"Umberto Carbonara,&nbsp;Giuseppe Lippolis,&nbsp;Luciano Rella,&nbsp;Paolo Minafra,&nbsp;Giuseppe Guglielmi,&nbsp;Antonio Vitarelli,&nbsp;Giuseppe Lucarelli,&nbsp;Pasquale Ditonno","doi":"10.1016/j.ajur.2023.05.005","DOIUrl":"https://doi.org/10.1016/j.ajur.2023.05.005","url":null,"abstract":"<div><h3>Objective</h3><p>In the last 10 years, robotic platforms allowed to resume of some alternative surgical approaches, including perineal robot-assisted radical prostatectomy (p-RARP). Herein, we present in detail the oncological and functional outcomes of patients who underwent p-RARP with a median follow-up of 30 months.</p></div><div><h3>Methods</h3><p>Patients presenting low- or intermediate-risk prostate cancer and prostate volume up to 60 mL who underwent p-RARP between November 2018 and November 2022 were selected. Baseline, intraoperative, pathological, and postoperative data were collected and then analyzed.</p></div><div><h3>Results</h3><p>Thirty-seven p-RARP cases were included. Such patients presented mean age of 62 years and a mean Charlson comorbidity index of 4. Body mass index of ≥25 kg/m<sup>2</sup> was reported by 24 (64.9%) patients, as well as 7 (18.9%) patients reported a past surgical history. Mean prostate volume and median prostate-specific antigen were 41 mL and 6.2 ng/mL, respectively. The median operative time was 242 min. The positive surgical margin rate was 45.9%. In terms of postoperative complications, 10 patients reported complications with any grade; however, a single case (2.7%) of major (Clavien-Dindo grade ≥3) complication was observed. No patient with biochemical recurrence or distant metastasis was reported at 2 years of follow-up. Recovery of continence rates were 67.6%, 75.7%, and 92.9%, at 6 months, 12 months, and 24 months after surgery, respectively.</p></div><div><h3>Conclusion</h3><p>p-RARP is a challenging but safe minimally invasive approach for selected patients with prostate cancer suitable for radical prostatectomy, showing outstanding functional recovery. Despite positive surgical margin rates being relatively high, no cases of biochemical recurrence or distant metastasis were reported after a median follow-up of 30 months.</p></div>","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"10 4","pages":"Pages 423-430"},"PeriodicalIF":2.6,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71771007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A national survey of lower urinary tract symptoms in Jordan 约旦下尿路症状的全国调查
IF 2.6 3区 医学 Q2 UROLOGY & NEPHROLOGY Pub Date : 2023-10-01 DOI: 10.1016/j.ajur.2021.12.010
Fadi Sawaqed , Ibrahim Kharboush , Mohammed Suoub , Ismail Albadawi , Mohmmad Alhawatmeh , Abdallah Murad

Objective

To determine the prevalence of lower urinary tract symptoms (LUTS) and their severity population in Jordan.

Methods

This cross-sectional survey was conducted using a paper-based survey between August and September in 2019. The study was carried out in the health care centers or hospitals in three different regions of Jordan: North (Irbid and Jarash), Middle (Amman, Madaba, Salt, and Zarqa), and South (Karak and Aqaba).

Results

To estimate the prevalence of LUTS, two definitions were used, including the first definition (presence of any LUTS regardless of the degree of severity) and the second definition (presence of any LUTS that occurs half the time or more). According to the first definition, 1038 (89.9%) reported LUTS (male: 47.3%, female: 52.7%), while 763 (66.1%) reported LUTS according to the second definition (male: 45.6%, female: 54.4%). According to the International Prostate Symptom Score characterization, 73.9% had nocturia and 62.9% reported daytime increased frequency.

Conclusion

LUTS are highly prevalent among the Jordanian population, and more than half of them have nocturia or daytime increased frequency as most frequently reported symptoms.

目的了解约旦地区下尿路症状(LUTS)的患病率及其严重程度。方法横断面调查于2019年8月至9月采用纸质调查方式进行。这项研究是在约旦三个不同地区的保健中心或医院进行的:北部(伊尔比德和贾拉什)、中部(安曼、马达巴、索特和扎尔卡)和南部(卡拉克和亚喀巴)。结果为了估计LUTS的患病率,使用了两种定义,包括第一种定义(无论严重程度是否存在任何LUTS)和第二种定义(发生一半或更多时间的任何LUTS)。根据第一种定义有1038例(89.9%)报告LUTS,其中男性:47.3%,女性:52.7%;根据第二种定义有763例(66.1%)报告LUTS,男性:45.6%,女性:54.4%。根据国际前列腺症状评分特征,73.9%有夜尿症,62.9%报告白天频率增加。结论luts在约旦人群中非常普遍,其中超过一半的人以夜尿症或白天频率增加为最常见的症状。
{"title":"A national survey of lower urinary tract symptoms in Jordan","authors":"Fadi Sawaqed ,&nbsp;Ibrahim Kharboush ,&nbsp;Mohammed Suoub ,&nbsp;Ismail Albadawi ,&nbsp;Mohmmad Alhawatmeh ,&nbsp;Abdallah Murad","doi":"10.1016/j.ajur.2021.12.010","DOIUrl":"10.1016/j.ajur.2021.12.010","url":null,"abstract":"<div><h3>Objective</h3><p>To determine the prevalence of lower urinary tract symptoms (LUTS) and their severity population in Jordan.</p></div><div><h3>Methods</h3><p>This cross-sectional survey was conducted using a paper-based survey between August and September in 2019. The study was carried out in the health care centers or hospitals in three different regions of Jordan: North (Irbid and Jarash), Middle (Amman, Madaba, Salt, and Zarqa), and South (Karak and Aqaba).</p></div><div><h3>Results</h3><p>To estimate the prevalence of LUTS, two definitions were used, including the first definition (presence of any LUTS regardless of the degree of severity) and the second definition (presence of any LUTS that occurs half the time or more). According to the first definition, 1038 (89.9%) reported LUTS (male: 47.3%, female: 52.7%), while 763 (66.1%) reported LUTS according to the second definition (male: 45.6%, female: 54.4%). According to the International Prostate Symptom Score characterization, 73.9% had nocturia and 62.9% reported daytime increased frequency.</p></div><div><h3>Conclusion</h3><p>LUTS are highly prevalent among the Jordanian population, and more than half of them have nocturia or daytime increased frequency as most frequently reported symptoms.</p></div>","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"10 4","pages":"Pages 518-525"},"PeriodicalIF":2.6,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43242569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
First 100 cases of transvesical single-port robotic radical prostatectomy 经膀胱单孔机器人根治性前列腺切除术100例
IF 2.6 3区 医学 Q2 UROLOGY & NEPHROLOGY Pub Date : 2023-10-01 DOI: 10.1016/j.ajur.2022.12.005
Roxana Ramos-Carpinteyro, Ethan L. Ferguson, Jaya S. Chavali, Albert Geskin, Jihad Kaouk

Objective

To describe the surgical technique and report the early outcomes of the transvesical (TV) approach to single-port (SP) robot-assisted radical prostatectomy.

Methods

All procedures were performed at a single center by one surgeon. We identified the first 100 consecutive patients with clinically localized prostate cancer that underwent SP TV robot-assisted radical prostatectomy using the da Vinci SP robotic surgical system. Data were collected prospectively and analyzed with descriptive statistics. The primary outcomes assessed were postoperative urinary continence, rate of biochemical recurrence, and sexual function.

Results

All procedures were performed without extra ports or conversion. The median age was 62.1 years and 49.0% of the patients had abdominal surgery history. The preoperative median prostate-specific antigen value and prostate volume were 5.0 ng/mL and 33.0 mL, respectively. There were no intraoperative complications. The median operative time and estimated blood loss were 212.5 min and 100.0 mL, respectively. A total of 92.0% of patients were discharged within 24.0 h, with an overall median length of stay of 5.6 h. Only 4.0% of patients required opioid prescriptions at discharge. The median Foley catheter duration was 3 days. Positive margins were present in 15.0% of cases. Median follow-up was 10.4 months. Continence rate was immediate after Foley removal in 49.0% of cases, 65.0% at 2 weeks, 77.4% at 6 weeks, 94.1% at 6 months, and 98.9% at 1 year. One case of biochemical recurrence (1.0%) was noted 3 months after surgery.

Conclusion

The SP TV approach for radical prostatectomy cases is a safe and feasible technique for patients with clinically localized prostate cancer. This technique offers advantages of short hospital stay, minimal narcotic use postoperatively, and promising early return of urinary continence, without compromising oncologic outcomes.

目的介绍经膀胱(TV)入路单孔(SP)机器人辅助根治性前列腺切除术的手术技术和早期疗效。方法所有手术均由一名外科医生在同一中心完成。我们确定了前100名连续的临床局限性前列腺癌患者,他们使用达芬奇SP机器人手术系统接受了SP TV机器人辅助的根治性前列腺切除术。前瞻性收集资料,用描述性统计进行分析。评估的主要结果是术后尿失禁、生化复发率和性功能。结果所有手术均完成,无额外端口或转换。中位年龄62.1岁,49.0%患者有腹部手术史。术前前列腺特异性抗原中位值5.0 ng/mL,前列腺体积33.0 mL。无术中并发症。中位手术时间为212.5 min,估计失血量为100.0 mL。92.0%的患者在24.0 h内出院,总体中位住院时间为5.6 h。只有4.0%的患者在出院时需要阿片类药物处方。Foley导管的中位持续时间为3天。在15.0%的病例中存在阳性边缘。中位随访时间为10.4个月。术后立即尿失禁率为49.0%,术后2周65.0%,术后6周77.4%,术后6个月94.1%,术后1年98.9%。术后3个月生化复发1例(1.0%)。结论SP TV入路对临床上局限性前列腺癌根治性切除术是一种安全可行的技术。该技术的优点是住院时间短,术后麻醉品使用最少,并且有望早期恢复尿失禁,而不影响肿瘤预后。
{"title":"First 100 cases of transvesical single-port robotic radical prostatectomy","authors":"Roxana Ramos-Carpinteyro,&nbsp;Ethan L. Ferguson,&nbsp;Jaya S. Chavali,&nbsp;Albert Geskin,&nbsp;Jihad Kaouk","doi":"10.1016/j.ajur.2022.12.005","DOIUrl":"10.1016/j.ajur.2022.12.005","url":null,"abstract":"<div><h3>Objective</h3><p>To describe the surgical technique and report the early outcomes of the transvesical (TV) approach to single-port (SP) robot-assisted radical prostatectomy.</p></div><div><h3>Methods</h3><p>All procedures were performed at a single center by one surgeon. We identified the first 100 consecutive patients with clinically localized prostate cancer that underwent SP TV robot-assisted radical prostatectomy using the da Vinci SP robotic surgical system. Data were collected prospectively and analyzed with descriptive statistics. The primary outcomes assessed were postoperative urinary continence, rate of biochemical recurrence, and sexual function.</p></div><div><h3>Results</h3><p>All procedures were performed without extra ports or conversion. The median age was 62.1 years and 49.0% of the patients had abdominal surgery history. The preoperative median prostate-specific antigen value and prostate volume were 5.0 ng/mL and 33.0 mL, respectively. There were no intraoperative complications. The median operative time and estimated blood loss were 212.5 min and 100.0 mL, respectively. A total of 92.0% of patients were discharged within 24.0 h, with an overall median length of stay of 5.6 h. Only 4.0% of patients required opioid prescriptions at discharge. The median Foley catheter duration was 3 days. Positive margins were present in 15.0% of cases. Median follow-up was 10.4 months. Continence rate was immediate after Foley removal in 49.0% of cases, 65.0% at 2 weeks, 77.4% at 6 weeks, 94.1% at 6 months, and 98.9% at 1 year. One case of biochemical recurrence (1.0%) was noted 3 months after surgery.</p></div><div><h3>Conclusion</h3><p>The SP TV approach for radical prostatectomy cases is a safe and feasible technique for patients with clinically localized prostate cancer. This technique offers advantages of short hospital stay, minimal narcotic use postoperatively, and promising early return of urinary continence, without compromising oncologic outcomes.</p></div>","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"10 4","pages":"Pages 416-422"},"PeriodicalIF":2.6,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45029898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Referring to the article published on p. 431–439 of this issue 参考本期第431-439页发表的文章
IF 2.6 3区 医学 Q2 UROLOGY & NEPHROLOGY Pub Date : 2023-10-01 DOI: 10.1016/j.ajur.2023.03.002
Reza Mehrazin, Shirin Razdan
{"title":"Referring to the article published on p. 431–439 of this issue","authors":"Reza Mehrazin,&nbsp;Shirin Razdan","doi":"10.1016/j.ajur.2023.03.002","DOIUrl":"https://doi.org/10.1016/j.ajur.2023.03.002","url":null,"abstract":"","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"10 4","pages":"Pages 388-389"},"PeriodicalIF":2.6,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71771071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Arterioureteral fistula: An unusual cause of haematuria 10 years after the implantation of a synthetic iliac-femoral stent 动脉输尿管瘘:人工髂股支架植入术后10年发生血尿的罕见原因
IF 2.6 3区 医学 Q2 UROLOGY & NEPHROLOGY Pub Date : 2023-10-01 DOI: 10.1016/j.ajur.2022.06.006
Luca Ongaro, Michele Rizzo, Francesco Claps, Ottavia Runti, Andrea Piasentin, Carlo Trombetta, Giovanni Liguori
{"title":"Arterioureteral fistula: An unusual cause of haematuria 10 years after the implantation of a synthetic iliac-femoral stent","authors":"Luca Ongaro,&nbsp;Michele Rizzo,&nbsp;Francesco Claps,&nbsp;Ottavia Runti,&nbsp;Andrea Piasentin,&nbsp;Carlo Trombetta,&nbsp;Giovanni Liguori","doi":"10.1016/j.ajur.2022.06.006","DOIUrl":"https://doi.org/10.1016/j.ajur.2022.06.006","url":null,"abstract":"","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"10 4","pages":"Pages 563-564"},"PeriodicalIF":2.6,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71771258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Penile vascular anomalies: A retrospective single center study and cumulative analysis of studies from China 阴茎血管异常:一项回顾性单中心研究和中国研究的累积分析
IF 2.6 3区 医学 Q2 UROLOGY & NEPHROLOGY Pub Date : 2023-10-01 DOI: 10.1016/j.ajur.2023.03.006
Chong Ma , Feng Gao , Ran An , Yawei Guan , Jingfei Teng , Xing Ai

Objective

Penile vascular anomalies (PVAs) or hemangioma can arouse patient concern about aesthetics and cause symptoms like bleeding and sexual dysfunction. However, its low incidence and the deficiency of large-volume studies hinder urologists from making informed decisions. This study aimed to investigate the clinical features and treatment experience of PVAs at the Seventh Medical Center of PLA General Hospital, Beijing, China. Furthermore, by systematically analysis of studies on PVAs in Chinese people, we aimed to provide novel insights on the management of this condition.

Methods

We retrospectively investigated clinical features and pathology of surgery-treated PVAs at our center. Moreover, by systemically reviewing the literature from PubMed and the three largest medical databases (China National Knowledge Infrastructure, Wan Fang, and Chinese Medical Journal Database) in China, we analyzed the clinical features and various therapies of PVAs in Chinese people.

Results

Between March 1, 2018 and March 1, 2023, a total of 356 cases with vascular anomalies were treated with surgery at out center. Only seven (2.0%) cases had lesions involving the perineum and external genitalia. All the seven cases were pathologically benign and demonstrated no recurrence over a follow-up period of 1–52 months (median 14 months). A total of 410 cases from 44 studies were selected in the cumulative analysis. Most patients (92.4%) diagnosed with PVAs were asymptomatic, and 68.8% of the patients were treated with sclerotherapy. As to the pathology, 57.1% were venous malformation.

Conclusion

The most common PVA is venous malformation and the majority of patients are asymptomatic. Sclerotherapy and laser have emerged as viable options for treating small lesions. Surgery still has its role in treating large lesions and obtaining pathology. Although PVAs often relapse or demand multiple treatments, the prognosis is favorable.

目的阴茎血管异常(PVAs)或血管瘤可引起患者对美观的担忧,引起出血、性功能障碍等症状。然而,它的低发病率和缺乏大量的研究阻碍了泌尿科医生做出明智的决定。本研究旨在探讨中国人民解放军总医院第七医学中心pva的临床特点及治疗经验。此外,通过对中国人pva研究的系统分析,我们旨在为这种疾病的治疗提供新的见解。方法回顾性分析本院手术治疗的pva的临床特点和病理特点。此外,通过系统查阅PubMed和中国三大医学数据库(中国国家知识基础设施、万方和中国医学期刊数据库)的文献,我们分析了中国人pva的临床特征和各种治疗方法。结果2018年3月1日至2023年3月1日,我院共收治血管异常356例。只有7例(2.0%)病变累及会阴和外生殖器。7例患者病理均为良性,随访1-52个月(中位14个月)无复发。从44项研究中选取410例病例进行累积分析。大多数确诊为pva的患者(92.4%)无症状,68.8%的患者接受了硬化治疗。病理上静脉畸形占57.1%。结论PVA以静脉畸形最为常见,多数患者无症状。硬化疗法和激光已经成为治疗小病变的可行选择。手术在治疗大病变和获得病理方面仍有其作用。虽然pva经常复发或需要多次治疗,但预后良好。
{"title":"Penile vascular anomalies: A retrospective single center study and cumulative analysis of studies from China","authors":"Chong Ma ,&nbsp;Feng Gao ,&nbsp;Ran An ,&nbsp;Yawei Guan ,&nbsp;Jingfei Teng ,&nbsp;Xing Ai","doi":"10.1016/j.ajur.2023.03.006","DOIUrl":"10.1016/j.ajur.2023.03.006","url":null,"abstract":"<div><h3>Objective</h3><p>Penile vascular anomalies (PVAs) or hemangioma can arouse patient concern about aesthetics and cause symptoms like bleeding and sexual dysfunction. However, its low incidence and the deficiency of large-volume studies hinder urologists from making informed decisions. This study aimed to investigate the clinical features and treatment experience of PVAs at the Seventh Medical Center of PLA General Hospital, Beijing, China. Furthermore, by systematically analysis of studies on PVAs in Chinese people, we aimed to provide novel insights on the management of this condition.</p></div><div><h3>Methods</h3><p>We retrospectively investigated clinical features and pathology of surgery-treated PVAs at our center. Moreover, by systemically reviewing the literature from PubMed and the three largest medical databases (China National Knowledge Infrastructure, Wan Fang, and Chinese Medical Journal Database) in China, we analyzed the clinical features and various therapies of PVAs in Chinese people.</p></div><div><h3>Results</h3><p>Between March 1, 2018 and March 1, 2023, a total of 356 cases with vascular anomalies were treated with surgery at out center. Only seven (2.0%) cases had lesions involving the perineum and external genitalia. All the seven cases were pathologically benign and demonstrated no recurrence over a follow-up period of 1–52 months (median 14 months). A total of 410 cases from 44 studies were selected in the cumulative analysis. Most patients (92.4%) diagnosed with PVAs were asymptomatic, and 68.8% of the patients were treated with sclerotherapy. As to the pathology, 57.1% were venous malformation.</p></div><div><h3>Conclusion</h3><p>The most common PVA is venous malformation and the majority of patients are asymptomatic. Sclerotherapy and laser have emerged as viable options for treating small lesions. Surgery still has its role in treating large lesions and obtaining pathology. Although PVAs often relapse or demand multiple treatments, the prognosis is favorable.</p></div>","PeriodicalId":46599,"journal":{"name":"Asian Journal of Urology","volume":"10 4","pages":"Pages 555-562"},"PeriodicalIF":2.6,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45367272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial by Reza Mehrazin and Shirin Razdan on p. 388–389 of this issue Reza Mehrazin和Shirin Razdan在本期第388-389页的社论
IF 2.6 3区 医学 Q2 UROLOGY & NEPHROLOGY Pub Date : 2023-10-01 DOI: 10.1016/j.ajur.2022.12.003
Ahmed Ghazi , Nitin Sharma , Ahmed Radwan , Hani Rashid , Thomas Osinski , Thomas Frye , William Tabayoyong , Jonathan Bloom , Jean Joseph

Objective

To evaluate the predictive validity of IRIS™ (Intuitive Surgical®, Sunnyvale, CA, USA) as a planning tool for robot-assisted partial nephrectomy (RAPN) by assessing the degree of overlap with intraoperative execution.

Methods

Thirty-one patients scheduled for RAPN by four experienced urologists were enrolled in a prospective study. Prior to surgery, urologists reviewed the IRIS™ three-dimensional model on an iphone Operating System (iOS) app and completed a questionnaire outlining their surgical plan including surgical approach, and ischemia technique as well as confidence in executing this plan. Postoperatively, questionnaires assessing the procedural approach, clinical utility, efficiency, and effectiveness of IRIS™ were completed. The degree of overlap between the preoperative and intraoperative questionnaires and between the planned approach and actual execution of the procedure was analyzed. Questionnaires were answered on a 5-point Likert scale and scores of 4 or greater were considered positive.

Results

Mean age was 65.1 years with a mean tumor size of 27.7 mm (interquartile range 17.5–44.0 mm). Hilar tumors consisted of 32.3%; 48.4% of patients had R.E.N.A.L. nephrometry scores of 7–9. On preoperative questionnaires, the surgeons reported that in 67.7% cases they were confident that they can perform the procedure successfully, and on intraoperative questionnaires, the surgeons reported that in 96.8% cases IRIS™ helped achieve good spatial sensation of the anatomy. There was a high degree of overlap between preoperative and intraoperative questionnaires for the surgical approach, interpreting anatomical details and clinical utility. When comparing plans for selective or off-clamp, the preoperative plan was executed in 90.0% of cases intraoperatively.

Conclusion

A high degree of overlap between the preoperative surgical approach and intraoperative RAPN execution was found using IRIS™. This is the first study to evaluate the predictive accuracy of IRIS™ during RAPN by comparing preoperative plan and intraoperative execution.

目的评价IRIS的预测有效性™ (Intuitive Surgical®,美国加利福尼亚州桑尼维尔)作为机器人辅助部分肾切除术(RAPN)的规划工具,通过评估与术中执行的重叠程度。方法31例由4位经验丰富的泌尿科医生安排的RAPN患者纳入一项前瞻性研究。手术前,泌尿科医生检查了IRIS™ 在iphone操作系统(iOS)应用程序上创建三维模型,并完成了一份问卷调查,概述了他们的手术计划,包括手术方法、缺血技术以及执行该计划的信心。术后,问卷评估IRIS的程序方法、临床效用、效率和有效性™ 已完成。分析了术前和术中问卷之间以及计划方法和实际手术执行之间的重叠程度。问卷采用5分Likert量表进行回答,4分或更高的分数被认为是积极的。结果平均年龄65.1岁,平均肿瘤大小27.7mm(四分位间距17.5~44.0mm),门部肿瘤占32.3%;48.4%的患者R.E.N.A.L.肾计量学评分为7-9。在术前问卷调查中,外科医生报告说,在67.7%的病例中,他们相信自己能够成功地进行手术。在术中问卷调查上,外科医生报告称,在96.8%的病例中IRIS™ 有助于实现良好的解剖空间感。手术入路、解剖细节解释和临床实用性的术前和术中问卷之间存在高度重叠。在比较选择性或非钳夹方案时,90.0%的病例在术中执行了术前方案。结论IRIS在术前手术入路和术中RAPN执行之间存在高度重叠™. 这是第一项评估IRIS预测准确性的研究™ 在RAPN期间,通过比较术前计划和术中执行。
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引用次数: 1
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Asian Journal of Urology
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