Asian Journal of Urology最新文献_第9页

Prediction of recurrence risk in patients with non-muscle-invasive bladder cancer 预测非肌层浸润性膀胱癌患者的复发风险

IF 2.4 3区医学 Q2 UROLOGY & NEPHROLOGY

Asian Journal of Urology

Pub Date : 2024-10-01 DOI: 10.1016/j.ajur.2023.04.007

Objective

Non-muscle-invasive bladder cancer (NMIBC) remains a common challenge in uro-oncology with conflicting reports on recurrence risk. This study aimed to elucidate the recurrence rate of NMIBC in the Cancer Clinic of Shahid Beheshti Hospital in Iran and to investigate related parameters affecting recurrence risk.

Methods

The data of 143 patients with NMIBC, who underwent treatment between January 2017 and January 2020 and were followed up from the initial transurethral resection of bladder tumor until November 30, 2020 in our institution, were retrospectively assessed. The Cox regression analysis and Kaplan–Meier plot of recurrence-free survival were used to determine independent contributing factors for tumor recurrence.

Results

Among patients with NMIBC, 83.9% were male, and 16.1% were female, with a mean age of 64.4 (standard deviation [SD] 12.9) years. During the follow-up, 71 (49.7%) patients showed tumor recurrence, with a mean recurrence time of 11.5 (SD 6.9) months. In the Chi-square test or Fisher's exact test, the age (≥65 years) (p=0.037), obesity (body mass index ≥30 kg/m²) (p=0.004), no diabetes mellitus (p=0.005), smoking (current or former smoker) (p=0.001), immediate perfusion therapy (p=0.035), number of tumors (>3) (p<0.001), and tumor stage (Ta, T1, and Tis) (p=0.001) had independent significant effects on the recurrence of NMIBC. The multivariate Cox regression analysis indicated that preoperative obesity (hazards ratio [HR] 7.90; 95% confidential interval [CI] 4.01–15.55; p<0.001), current or former smoking (HR 1.85; 95% CI 1.07–3.20; p=0.027), and a high-grade tumor (HR 4.03; 95% CI 1.59–10.25; p=0.003) were significant predictors of tumor recurrence. The Kaplan–Meier plot of recurrence-free survival showed that obesity (log-rank p<0.001), current or former smoking (log-rank p=0.001), and a high-grade tumor (log-rank p=0.006) were associated with a shorter time interval until the first tumor recurrence.

Conclusion

The study found a high recurrence rate of NMIBC in Iran from January 2017 to January 2020, with the obesity, smoking history, and the high-grade tumor as contributing factors.

目的非肌层浸润性膀胱癌（NMIBC）仍然是泌尿肿瘤学中的一个常见难题，有关其复发风险的报道相互矛盾。本研究旨在阐明伊朗沙希德-贝赫什提医院癌症诊所的非肌层浸润性膀胱癌复发率，并调查影响复发风险的相关参数。方法回顾性评估了我院在 2017 年 1 月至 2020 年 1 月期间接受治疗的 143 例非肌层浸润性膀胱癌患者的数据，这些患者从最初的经尿道膀胱肿瘤切除术开始随访，直至 2020 年 11 月 30 日。结果在NMIBC患者中，83.9%为男性，16.1%为女性，平均年龄为64.4（标准差[SD]12.9）岁。随访期间，71 例（49.7%）患者肿瘤复发，平均复发时间为 11.5 个月（标准差 6.9 个月）。在卡方检验或费雪精确检验中，年龄（≥65 岁）（P=0.037）、肥胖（体重指数≥30 kg/m2）（P=0.004）、无糖尿病（P=0.005）、吸烟（目前或曾经吸烟）（P=0.001）、立即灌注治疗（p=0.035）、肿瘤数目（>3）（p<0.001）和肿瘤分期（Ta、T1和Tis）（p=0.001）对NMIBC的复发有独立的显著影响。多变量 Cox 回归分析表明，术前肥胖（危险比 [HR] 7.90；95% 置信区间 [CI]4.01-15.55；p<0.001）、目前或曾经吸烟（HR 1.85；95% CI 1.07-3.20；p=0.027）和高级别肿瘤（HR 4.03；95% CI 1.59-10.25；p=0.003）是肿瘤复发的重要预测因素。无复发生存期的卡普兰-梅耶尔图显示，肥胖（对数秩p<0.001）、目前或曾经吸烟（对数秩p=0.001）和高级别肿瘤（对数秩p=0.006）与肿瘤首次复发前的时间间隔较短有关。结论该研究发现，从2017年1月至2020年1月，伊朗的NMIBC复发率较高，肥胖、吸烟史和高级别肿瘤是诱因。

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引用次数: 0

Efficacy and safety of platelet-rich plasma intracavernous injection for patients with erectile dysfunction: A systematic review, meta-analysis, and meta-regression 富血小板血浆鞘膜内注射治疗勃起功能障碍患者的有效性和安全性：系统回顾、荟萃分析和荟萃回归

IF 2.4 3区医学 Q2 UROLOGY & NEPHROLOGY

Asian Journal of Urology

Pub Date : 2024-10-01 DOI: 10.1016/j.ajur.2024.01.001

Objective

Intracavernous injection might be offered to patients with erectile dysfunction (ED) who did not respond to the first-line oral treatment. Platelet-rich plasma (PRP) might offer improvement in erectile function since it contains numerous growth factors. This study aimed to evaluate the efficacy and safety of PRP intracavernous injection for patients with ED.

Methods

We conducted relevant literature searches on Cochrane Library, Medline, Scopus, and ClinicalTrials.gov databases using specific keywords. The results of continuous variables were pooled into the mean difference (MD) and dichotomous variables into the odds ratio along with 95% confidence interval (95% CI).

Results

A total of six studies were included. Our pooled analysis revealed that PRP intracavernous injection was associated with a significant increase in the erectile function domain of the International Index of Erectile Function at 1 month (MD 3.47 [95% CI 2.62–4.32], p<0.00001, I²=7%), 3 months (MD 3.19 [95% CI 2.25–4.12], p<0.00001, I²=0%), and 6 months (MD 3.21 [95% CI 2.30–4.13], p<0.00001, I²=0%) after the intervention when compared with baseline values. PRP was also superior to a placebo in terms of improvement in erectile function domain of the International Index of Erectile Function score at 1 month (MD 2.83, p<0.00001), 3 months (MD 2.87, p<0.00001), and 6 months (MD 3.20, p<0.00001) post-intervention. The adverse events from PRP injection were only mild without any serious adverse events.

Conclusion

PRP intracavernous injection may offer benefits in improving erectile function in patients with ED with a relatively good safety profile.

目的对于口服一线治疗无效的勃起功能障碍（ED）患者，可进行阴茎海绵体内注射。富血小板血浆（PRP）含有多种生长因子，可改善勃起功能。本研究旨在评估PRP海绵体内注射治疗ED患者的有效性和安全性。方法我们使用特定关键词在Cochrane Library、Medline、Scopus和ClinicalTrials.gov数据库中进行了相关文献检索。结果共纳入六项研究。我们的汇总分析表明，PRP鞘膜内注射与一个月后国际勃起功能指数（International Index of Erectile Function）中勃起功能域的显著增加有关（MD 3.47 [95% CI 2.62-4.32]，p<0.00001，I2=7%）、3个月（MD 3.19 [95% CI 2.25-4.12]，p<0.00001，I2=0%）和6个月（MD 3.21 [95% CI 2.30-4.13]，p<0.00001，I2=0%）后与基线值相比均有明显提高。在干预后 1 个月（MD 2.83，p<0.00001）、3 个月（MD 2.87，p<0.00001）和 6 个月（MD 3.20，p<0.00001）的国际勃起功能指数评分中，PRP 在勃起功能改善方面也优于安慰剂。结论 PRP 海绵体内注射可改善 ED 患者的勃起功能，且安全性相对较好。

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引用次数: 0

Correlation analysis between urinary crystals and upper urinary calculi 尿结晶与上尿路结石的相关性分析

IF 2.4 3区医学 Q2 UROLOGY & NEPHROLOGY

Asian Journal of Urology

Pub Date : 2024-10-01 DOI: 10.1016/j.ajur.2024.04.003

Objective

This study aimed to analyze the correlation between urinary crystals and urinary calculi.

Methods

Clinical data, including urinary crystal types, were collected from 237 patients with urinary calculi. The detection rate of urine crystals and their correlation with stone composition were analyzed. The receiver operating characteristic curve analysis was used to determine the best cut-off value for predicting stone formation risk based on calcium oxalate crystals in urine.

Results

Calcium oxalate was the most common component in 237 patients. Among them, 201 (84.81%) patients had stones containing calcium oxalate. In these patients, calcium oxalate crystals were detected in 45.77% (92/201) of cases. In different groups of calcium oxalate stones, calcium oxalate crystals accounted for more than 90% of the total number of crystals detected in each group. The detection rate of calcium oxalate crystals was higher in first-time stone formers than in recurrent patients. The receiver operating characteristic curve analysis suggested a cut-off value of 110 crystals/μL for predicting stone formation, validated with 65 patients and 100 normal people.

Conclusion

Calcium oxalate crystals in urine can predict the composition of calcium oxalate stones and indicate a higher risk of stone formation when the number exceeds 110 crystals/μL. This non-invasive method may guide clinical treatment and prevention strategies.

方法收集 237 名尿路结石患者的临床数据，包括尿路结石类型。分析了尿液结晶的检出率及其与结石成分的相关性。根据尿液中的草酸钙结晶，采用接收者操作特征曲线分析法确定预测结石形成风险的最佳临界值。其中，201 名患者（84.81%）的结石中含有草酸钙。在这些患者中，45.77%（92/201）的病例检测出草酸钙结晶。在不同组别的草酸钙结石中，草酸钙结晶占每组检出结晶总数的 90%以上。首次结石患者的草酸钙结晶检出率高于复发患者。结论尿液中的草酸钙结晶可预测草酸钙结石的成分，当结晶数量超过 110 个/μL 时，结石形成的风险较高。这种无创方法可为临床治疗和预防策略提供指导。

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引用次数: 0

Robot-assisted radical cystectomy with neobladder diversion in females: Safety profile and functional outcomes 女性机器人辅助根治性膀胱切除术与新膀胱转流术：安全性和功能性结果

IF 2.4 3区医学 Q2 UROLOGY & NEPHROLOGY

Asian Journal of Urology

Pub Date : 2024-10-01 DOI: 10.1016/j.ajur.2024.02.008

Objective

Radical cystectomy (RC) is a standard treatment for localized muscle invasive bladder cancer and high-risk or very high-risk non-muscle invasive bladder cancer not responding to adequate endovesical therapy. In women, traditionally RC is performed with hystero-adnexectomy and resection of the anterior vaginal wall, often resulting in sexual disorders. Vaginal-sparing techniques have been developed to improve functional outcomes. The present study explores the safety and the functional outcome of vaginal-sparing techniques.

Methods

We retrospectively analyzed all consecutive female patients undergoing robot-assisted RC (RARC) with neobladder diversion between October 2017 and February 2022. The indications for vaginal-sparing RC were absence of tumor on bladder neck or urethra and no sign of infiltration of posterior bladder wall at the preoperative MRI. Functional results were evaluated with the aid of five questions out of the Bladder Cancer Index questionnaire. Complications were reported according to the Clavien–Dindo classification and cancer control was evaluated by recurrence-free and cancer-specific survival.

Results

A total of 22 female patients underwent RARC with neobladder diversion. Neoadjuvant chemotherapy was given in 17 (77%) cases. Clavien–Dindo grades III–IV complications occurred in four (18%) cases. After a mean follow-up of 29 (interquartile range 16–44) months, six (27.3%) patients developed distant metastases, and one (4.5%) woman loco-regional relapse. Sexual-sparing surgery was performed in 19 (86%) patients, and in the others the anterior vaginal wall was resected, but neobladder was still performed. During daytime, no patients reported total incontinence and 73% (11/15) reported total continence or only occasional leaks. Sexual results showed that seven of 15 (47%) women regained sexual activity after surgery, with a quality reported as “good” or “very good” in 40% of all 19 cases.

Conclusion

RARC in female with anterior vaginal wall preservation is feasible. The approach showed a good safety profile, with satisfying results on continence and sexual activity. Sexual-sparing approaches should be carried out after correct patient selection.

目的良性膀胱切除术（RC）是治疗局部肌层浸润性膀胱癌和对适当的腔内治疗无效的高危或极高危非肌层浸润性膀胱癌的标准疗法。对女性而言，传统的膀胱切除术是在子宫附件切除术和阴道前壁切除术的基础上进行的，这往往会导致性功能障碍。为了改善功能性结果，人们开发了阴道保留技术。本研究探讨了阴道保留技术的安全性和功能性结果。方法我们回顾性分析了2017年10月至2022年2月期间所有接受机器人辅助RC（RARC）和新膀胱转流术的连续女性患者。保留阴道的 RC 适应症为膀胱颈部或尿道无肿瘤，术前 MRI 检查无膀胱后壁浸润迹象。功能结果通过膀胱癌指数问卷中的五个问题进行评估。并发症根据 Clavien-Dindo 分类法进行报告，癌症控制情况根据无复发生存率和癌症特异性生存率进行评估。17例（77%）患者接受了新辅助化疗。4例（18%）患者出现了克拉维恩-丁多（Clavien-Dindo）III-IV级并发症。平均随访29个月（四分位间范围16-44个月）后，6例（27.3%）患者出现远处转移，1例（4.5%）女性患者局部区域复发。19例（86%）患者进行了保留性生活的手术，其他患者切除了阴道前壁，但仍进行了新膀胱术。白天，没有患者报告完全失禁，73%（11/15）的患者报告完全失禁或仅偶尔漏尿。性生活结果显示，15 名女性中有 7 名（47%）在术后恢复了性生活，在所有 19 例患者中，40% 的患者报告性生活质量为 "良好 "或 "非常好"。结论：保留阴道前壁的女性 RARC 是可行的，这种方法的安全性良好，在排便和性活动方面的效果令人满意。应在正确选择患者后再实施保留性器官的方法。

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引用次数: 0

LncRNA HCG18 promotes prostate cancer progression by regulating the miR-512-3p/HK-2 axis LncRNA HCG18通过调控miR-512-3p/HK-2轴促进前列腺癌进展

IF 2.4 3区医学 Q2 UROLOGY & NEPHROLOGY

Asian Journal of Urology

Pub Date : 2024-10-01 DOI: 10.1016/j.ajur.2024.01.007

Objective

Long non-coding RNAs (lncRNAs) play an important role in tumor progression. Numerous studies show that lncRNAs are strongly associated with prostate cancer (PCa) progression. The aim of this study was to investigate the pathway through which lncRNA HCG18 regulates PCa progression by bioinformatics analysis and experiments.

Methods

We compared HCG18 expression in PCa versus normal tissue and cells by data and cell lines, followed by comparing the changes in tumor cell proliferation, migration, and invasive ability after knockdown of HCG18. Then we searched for its downstream pathway by database and validated the pathway in vivo and in vitro.

Results

HCG18 was highly expressed in PCa and has the ability to promote tumor proliferation, migration, and invasion; knockdown of HCG18 led to a decrease in the ability of cells to do so, which can be reversed by knockdown of miR-512-3p or overexpression of hexokinase 2.

Conclusion

Our in vivo and in vitro experiments suggest that HCG18 can play a role in promoting PCa progression by blocking the inhibition of hexokinase 2 by miR-512-3p via sponge adsorption.

目的长非编码 RNA（lncRNA）在肿瘤进展中发挥着重要作用。大量研究表明，lncRNA 与前列腺癌（PCa）的进展密切相关。方法我们通过数据和细胞系比较了HCG18在PCa与正常组织和细胞中的表达情况，然后比较了敲除HCG18后肿瘤细胞增殖、迁移和侵袭能力的变化。结果HCG18在PCa中高表达，具有促进肿瘤增殖、迁移和侵袭的能力；敲除HCG18会导致细胞增殖、迁移和侵袭能力下降，而敲除miR-512-3p或过表达己糖激酶2可以逆转这种下降。结论我们的体内和体外实验表明，HCG18可通过海绵吸附阻断miR-512-3p对己糖激酶2的抑制，从而在促进PCa进展方面发挥作用。

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引用次数: 0

A diagnostic challenge: Eosinophilic cystitis masquerading as bladder cancer with seminal vesicle invasion 诊断难题：嗜酸性粒细胞性膀胱炎伪装成精囊受侵的膀胱癌

IF 2.4 3区医学 Q2 UROLOGY & NEPHROLOGY

Asian Journal of Urology

Pub Date : 2024-10-01 DOI: 10.1016/j.ajur.2023.07.004

Anshuman Singh, Kasi Viswanath Gali, Vivek Pai, Padmaraj Hegde

引用次数: 0

Is fluoroscopy-free single-use flexible ureteroscopy a feasible treatment for kidney stones with abnormal renal anatomy? 对于肾解剖异常的肾结石，无荧光镜的一次性柔性输尿管镜是可行的治疗方法吗？

IF 2.4 3区医学 Q2 UROLOGY & NEPHROLOGY

Asian Journal of Urology

Pub Date : 2024-10-01 DOI: 10.1016/j.ajur.2023.05.004

Objective

This study aimed to evaluate the feasibility of the fluoroscopy-free single-use flexible ureteroscopy procedure in the treatment of kidney stones with abnormal renal anatomy compared to normal renal anatomy.

Methods

Forty patients with abnormal (Group A) and 80 patients with normal (Group B) renal anatomy who had 10–20 mm renal stones were included. They were treated with LithoVue single-use flexible ureteroscopy (Boston Scientific, Marlborough, MA, USA) after ureteric dilatation by two different size semi-rigid ureteroscopes. This technique was chosen as the aim was to exclude any ureteric pathology (e.g., stone or stricture), confirm the placement of a safe guidewire, avoid balloon dilatation of the ureter, and achieve safe insertion of a 12 Fr, 35/45 cm ureteric access sheath with optical and tactile sign and without fluoroscopy image for guidance.

Results

The mean ages were 43 years and 45 years in Group A and Group B, respectively. The mean stone burden was 14.62 (standard deviation: 5.35) mm³ and 14.79 (standard deviation: 4.58) mm³ in Group A and Group B, respectively. There is no significant difference between both groups according to the mean operative time, hospital stay, or stone-free rate. The stone-free rate was about 93% in both groups when the stone size was between 10 mm and 15 mm, and less than 54% when the stone size was more than 15 mm to 20 mm. In the majority of cases (80.0% in Group A and 92.5% in Group B), we completed the procedure without fluoroscopy. The perioperative complication rates were comparable in the two groups.

Conclusion

Fluoroscopy-free single-use flexible ureteroscopy, when performed by expert urologists, is a feasible treatment for pre-stented patients with kidney calculi of ≤15 mm with abnormal renal anatomy.

本研究旨在评估与正常肾脏解剖结构相比，无透视一次性使用柔性输尿管镜手术治疗肾脏解剖结构异常的肾结石的可行性。他们在使用两种不同尺寸的半硬性输尿管镜扩张输尿管后，接受了LithoVue一次性使用柔性输尿管镜（Boston Scientific, Marlborough, MA, USA）的治疗。选择该技术的目的是排除任何输尿管病变（如结石或狭窄），确认安全导丝的放置，避免输尿管球囊扩张，并在有光学和触觉标志、无透视图像引导的情况下安全插入 12 Fr、35/45 cm 输尿管通路鞘管。A 组和 B 组的平均结石量分别为 14.62（标准差：5.35）立方毫米和 14.79（标准差：4.58）立方毫米。两组在平均手术时间、住院时间和无结石率方面无明显差异。当结石大小在 10 毫米至 15 毫米之间时，两组的无结石率约为 93%，而当结石大小超过 15 毫米至 20 毫米时，无结石率低于 54%。大多数病例（A 组 80.0%，B 组 92.5%）无需透视即可完成手术。结论对于肾结石≤15 毫米且肾脏解剖结构异常的预留支架患者，由泌尿科专家进行无荧光透视一次性使用柔性输尿管镜检查是一种可行的治疗方法。

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引用次数: 0

Search trends in the treatment for benign prostatic hyperplasia: A twenty-year analysis 良性前列腺增生治疗的搜索趋势：二十年分析

IF 2.4 3区医学 Q2 UROLOGY & NEPHROLOGY

Asian Journal of Urology

Pub Date : 2024-10-01 DOI: 10.1016/j.ajur.2023.08.009

Objective

Minimally invasive treatments for benign prostatic hyperplasia (BPH) have seen an increase in usage in recent years. We aimed to determine what types of events may influence patient search habits related to surgical BPH treatments.

Methods

Google Trends was used to determine the frequency of searches for different minimally invasive and prostatic ablative treatments for BPH in the United States. The procedures including transurethral resection of the prostate (TURP), Aquablation therapy (Aquablation), Greenlight laser therapy (Greenlight), transurethral needle ablation, transurethral microwave thermotherapy, Urolift (prostatic urethral lift [PUL]), Rezum, iTind, holmium laser enucleation of the prostate, simple prostatectomy, and prostatic artery embolization were compared.

Results

From January 1, 2004 to February 28, 2023, the number of internet search queries have increased for TURP, PUL, Rezum, prostatic artery embolization, and holmium laser enucleation of the prostate. There has been a slight decrease in searches for Greenlight, transurethral needle ablation, transurethral microwave thermotherapy, iTind, simple prostatectomy, and Aquablation.

Conclusion

Despite increased searches of alternatives, TURP remains the most searched BPH procedure. Additionally, search habits may be influenced by several factors including government approval, corporate acquisition, and marketing campaigns. It is important for physicians to understand the types of events that may cause patients to inquire about certain treatments for better quality health information and clinical visits.

目的近年来，良性前列腺增生症（BPH）的微创治疗方法的使用率有所上升。我们旨在确定哪些类型的事件可能会影响患者搜索良性前列腺增生手术治疗方法的习惯。方法使用谷歌趋势来确定美国不同良性前列腺增生微创和前列腺消融治疗方法的搜索频率。比较的治疗方法包括经尿道前列腺切除术（TURP）、水消融治疗（Aquablation）、绿光激光治疗（Greenlight）、经尿道针消融术、经尿道微波热疗、Urolift（前列腺尿道提升术 [PUL]）、Rezum、iTind、前列腺钬激光去核术、单纯前列腺切除术和前列腺动脉栓塞术。结果从 2004 年 1 月 1 日到 2023 年 2 月 28 日，有关 TURP、PUL、Rezum、前列腺动脉栓塞术和前列腺钬激光去核术的互联网搜索查询次数有所增加。结论尽管替代方法的搜索次数有所增加，但TURP仍是搜索次数最多的良性前列腺增生手术。此外，搜索习惯可能受到政府批准、企业收购和营销活动等多种因素的影响。对于医生来说，重要的是了解可能导致患者询问某些治疗方法的事件类型，以获得更高质量的健康信息和临床就诊。

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引用次数: 0

Virtual and augmented reality systems and three-dimensional printing of the renal model—novel trends to guide preoperative planning for renal cancer 虚拟和增强现实系统及三维打印肾脏模型--指导肾癌术前规划的新趋势

IF 2.4 3区医学 Q2 UROLOGY & NEPHROLOGY

Asian Journal of Urology

Pub Date : 2024-10-01 DOI: 10.1016/j.ajur.2023.10.004

Objective

This study aimed to explore the applications of three-dimensional (3D) technology, including virtual reality, augmented reality (AR), and 3D printing system, in the field of medicine, particularly in renal interventions for cancer treatment.

Methods

A specialized software transforms 2D medical images into precise 3D digital models, facilitating improved anatomical understanding and surgical planning. Patient-specific 3D printed anatomical models are utilized for preoperative planning, intraoperative guidance, and surgical education. AR technology enables the overlay of digital perceptions onto real-world surgical environments.

Results

Patient-specific 3D printed anatomical models have multiple applications, such as preoperative planning, intraoperative guidance, trainee education, and patient counseling. Virtual reality involves substituting the real world with a computer-generated 3D environment, while AR overlays digitally created perceptions onto the existing reality. The advances in 3D modeling technology have sparked considerable interest in their application to partial nephrectomy in the realm of renal cancer. 3D printing, also known as additive manufacturing, constructs 3D objects based on computer-aided design or digital 3D models. Utilizing 3D-printed preoperative renal models provides benefits for surgical planning, offering a more reliable assessment of the tumor's relationship with vital anatomical structures and enabling better preparation for procedures. AR technology allows surgeons to visualize patient-specific renal anatomical structures and their spatial relationships with surrounding organs by projecting CT/MRI images onto a live laparoscopic video. Incorporating patient-specific 3D digital models into healthcare enhances best practice, resulting in improved patient care, increased patient satisfaction, and cost saving for the healthcare system.

本研究旨在探索三维（3D）技术，包括虚拟现实、增强现实（AR）和三维打印系统在医学领域的应用，尤其是在肾脏介入治疗癌症方面的应用。病人专用的三维打印解剖模型可用于术前规划、术中指导和手术教育。结果特定患者的三维打印解剖模型有多种应用，如术前规划、术中指导、受训者教育和患者咨询。虚拟现实是用计算机生成的三维环境取代现实世界，而 AR 则是将数字创建的感知叠加到现有的现实环境中。三维建模技术的进步引发了人们对其在肾癌肾部分切除术中应用的浓厚兴趣。三维打印也称为增材制造，是根据计算机辅助设计或数字三维模型构建三维物体。利用三维打印的术前肾脏模型有利于制定手术计划，对肿瘤与重要解剖结构的关系进行更可靠的评估，为手术做好更充分的准备。AR 技术通过将 CT/MRI 图像投射到实时腹腔镜视频上，使外科医生能够直观地看到患者特定的肾脏解剖结构及其与周围器官的空间关系。将特定于患者的三维数字模型融入医疗保健中可增强最佳实践，从而改善患者护理，提高患者满意度，并为医疗保健系统节约成本。

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引用次数: 0

Prostatic small cell carcinoma with resultant tumor thrombus to the right iliac vein 前列腺小细胞癌导致右髂静脉肿瘤血栓形成

IF 2.4 3区医学 Q2 UROLOGY & NEPHROLOGY

Asian Journal of Urology

Pub Date : 2024-10-01 DOI: 10.1016/j.ajur.2024.01.004

引用次数: 0