Darshita Shukla, Shiji Chalipat, Sanjay Chavan, S. Agarkhedkar, Sudhir Malwade, Vishwanath S Kulkarni
{"title":"Etiological spectrum and predictors of intractability in early-onset epilepsy (3 months–2 years): A cross-sectional observational study","authors":"Darshita Shukla, Shiji Chalipat, Sanjay Chavan, S. Agarkhedkar, Sudhir Malwade, Vishwanath S Kulkarni","doi":"10.4103/jpn.jpn_100_21","DOIUrl":"https://doi.org/10.4103/jpn.jpn_100_21","url":null,"abstract":"","PeriodicalId":46746,"journal":{"name":"Journal of Pediatric Neurosciences","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70816739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Magnitude, determinants, and impact of treatment lag in West syndrome: A prospective observational study","authors":"J. Sahu, Abinaya Anbarasu, N. Sankhyan, P. Singhi","doi":"10.4103/jpn.jpn_101_21","DOIUrl":"https://doi.org/10.4103/jpn.jpn_101_21","url":null,"abstract":"","PeriodicalId":46746,"journal":{"name":"Journal of Pediatric Neurosciences","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70817337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: Stroke is relatively rare in children, but it can lead to significant morbidity and mortality. Understanding the risk factors related to stroke will optimize the outcomes in children. Published cohorts of children with stroke recurrence rates are variable. This study has been done to determine the risk factors, clinical features, and outcomes of recurrent pediatric stroke in a developing country. Materials and Methods: We enrolled 98 children with stroke: 16 children were excluded due to incomplete investigations and were lost to follow-up. This study was conducted in a tertiary care hospital in Dhaka, Bangladesh from January 2017 to December 2019. Detailed investigations regarding stroke, physical examination, and targeted investigations were done. Results: We studied 82 patients: Among them, 52 had their 1st attack, and 30 had recurrent attacks of stroke. The age range of onset of stroke was 4.78 ± 3.90 and 5.30 ± 4.25 in the first and recurrent stroke, respectively. In this study, 36.5% of the enrolled children presented with a recurrence of stroke, whereas the rest presented with the first episode of stroke. The most common cause of recurrent stroke was intracranial vasculopathy, with the most common being vascular narrowing and moya moya disease (MMD). Protein C deficiency was observed more frequently in recurrent stroke. No significant difference was found in the risk factors of the first and recurrent stroke. During follow-up, patients with recurrent stroke developed cognitive decline, epilepsy, and speech disorder more frequently. Conclusion: In children with recurrent stroke vasculopathy, particularly MMD and protein C deficiency were observed more frequently. Moreover, in this group, sequelae-like cognitive dysfunction, speech disorder, and epilepsy were observed more frequently.
{"title":"Risk factors, clinical characteristics, and outcomes of recurrent pediatric stroke: A study from Bangladesh","authors":"K. Fatema, M. Rahman","doi":"10.4103/jpn.jpn_193_20","DOIUrl":"https://doi.org/10.4103/jpn.jpn_193_20","url":null,"abstract":"Objective: Stroke is relatively rare in children, but it can lead to significant morbidity and mortality. Understanding the risk factors related to stroke will optimize the outcomes in children. Published cohorts of children with stroke recurrence rates are variable. This study has been done to determine the risk factors, clinical features, and outcomes of recurrent pediatric stroke in a developing country. Materials and Methods: We enrolled 98 children with stroke: 16 children were excluded due to incomplete investigations and were lost to follow-up. This study was conducted in a tertiary care hospital in Dhaka, Bangladesh from January 2017 to December 2019. Detailed investigations regarding stroke, physical examination, and targeted investigations were done. Results: We studied 82 patients: Among them, 52 had their 1st attack, and 30 had recurrent attacks of stroke. The age range of onset of stroke was 4.78 ± 3.90 and 5.30 ± 4.25 in the first and recurrent stroke, respectively. In this study, 36.5% of the enrolled children presented with a recurrence of stroke, whereas the rest presented with the first episode of stroke. The most common cause of recurrent stroke was intracranial vasculopathy, with the most common being vascular narrowing and moya moya disease (MMD). Protein C deficiency was observed more frequently in recurrent stroke. No significant difference was found in the risk factors of the first and recurrent stroke. During follow-up, patients with recurrent stroke developed cognitive decline, epilepsy, and speech disorder more frequently. Conclusion: In children with recurrent stroke vasculopathy, particularly MMD and protein C deficiency were observed more frequently. Moreover, in this group, sequelae-like cognitive dysfunction, speech disorder, and epilepsy were observed more frequently.","PeriodicalId":46746,"journal":{"name":"Journal of Pediatric Neurosciences","volume":"1 1","pages":"46 - 53"},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70818641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Guillain-Barré syndrome (GBS) and acute disseminated encephalomyelitis (ADEM) are postinfectious, inflammatory, and neurological disorders involving the peripheral and central nervous system, respectively. Although the clinical features are distinct, they share a common pathogenesis. Both the disorders are not uncommon in children. Concurrent GBS and ADEM occurring simultaneously is a rare entity. We are reporting a case of a 5-year-old boy presenting with acute-onset ascending paralysis with irritability, hyperreflexia, and positive Babinski sign. This patient was diagnosed as having both GBS and ADEM. The CSF albumin-cytological disassociation, electrophysiological diagnosis, and MRI of brain supported the concurrent present of the two disorders.
{"title":"Concurrent Guillain-Barré syndrome and acute disseminated encephalomyelitis in a child: A case report from Bangladesh","authors":"K. Fatema, M. Rahman, S. Akhter","doi":"10.4103/jpn.jpn_275_20","DOIUrl":"https://doi.org/10.4103/jpn.jpn_275_20","url":null,"abstract":"Guillain-Barré syndrome (GBS) and acute disseminated encephalomyelitis (ADEM) are postinfectious, inflammatory, and neurological disorders involving the peripheral and central nervous system, respectively. Although the clinical features are distinct, they share a common pathogenesis. Both the disorders are not uncommon in children. Concurrent GBS and ADEM occurring simultaneously is a rare entity. We are reporting a case of a 5-year-old boy presenting with acute-onset ascending paralysis with irritability, hyperreflexia, and positive Babinski sign. This patient was diagnosed as having both GBS and ADEM. The CSF albumin-cytological disassociation, electrophysiological diagnosis, and MRI of brain supported the concurrent present of the two disorders.","PeriodicalId":46746,"journal":{"name":"Journal of Pediatric Neurosciences","volume":"47 1","pages":"75 - 78"},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70819183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Karnavat, A. Hegde, Shilpa D. Kulkarni, Roshan Kore, Bhakti Tulaskar, Suvarna Sawant, Omkar Hajirnis
{"title":"Ketogenic diet in children with drug refractory epilepsy: Do we need 4:1 ketogenic ratio?","authors":"P. Karnavat, A. Hegde, Shilpa D. Kulkarni, Roshan Kore, Bhakti Tulaskar, Suvarna Sawant, Omkar Hajirnis","doi":"10.4103/jpn.jpn_177_21","DOIUrl":"https://doi.org/10.4103/jpn.jpn_177_21","url":null,"abstract":"","PeriodicalId":46746,"journal":{"name":"Journal of Pediatric Neurosciences","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70817928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vykuntaraju K Gowda, Gururaju Daasara, N. Nanjundappa, Vani H. Nagarajappa, Sanjay K. Shivappa
{"title":"Prevalence of peripheral neuropathy in children with type 1 diabetes mellitus","authors":"Vykuntaraju K Gowda, Gururaju Daasara, N. Nanjundappa, Vani H. Nagarajappa, Sanjay K. Shivappa","doi":"10.4103/jpn.jpn_179_21","DOIUrl":"https://doi.org/10.4103/jpn.jpn_179_21","url":null,"abstract":"","PeriodicalId":46746,"journal":{"name":"Journal of Pediatric Neurosciences","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70817942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A study on behavioral disorders, academic difficulties, and parental handling patterns in children with epilepsy","authors":"N. Sawant, Rashmi K Singh, R. Vaswani","doi":"10.4103/jpn.jpn_210_21","DOIUrl":"https://doi.org/10.4103/jpn.jpn_210_21","url":null,"abstract":"","PeriodicalId":46746,"journal":{"name":"Journal of Pediatric Neurosciences","volume":"38 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70818481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Primary intracranial Ewing’s sarcoma/peripheral primitive neuroectodermal tumor in pediatric age group: A comprehensive review of literature","authors":"Mohammad Elbaroody, A. Abdullah","doi":"10.4103/jpn.jpn_198_21","DOIUrl":"https://doi.org/10.4103/jpn.jpn_198_21","url":null,"abstract":"","PeriodicalId":46746,"journal":{"name":"Journal of Pediatric Neurosciences","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70818732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"En plaque tuberculoma of the dura with extracranial extension in an adolescent mimicking an aggressive en plaque meningioma","authors":"P. Krishnan, Nabanita Ghosh, Sugat Sanyal","doi":"10.4103/jpn.jpn_79_21","DOIUrl":"https://doi.org/10.4103/jpn.jpn_79_21","url":null,"abstract":"","PeriodicalId":46746,"journal":{"name":"Journal of Pediatric Neurosciences","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70820190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Laparoscopic peritoneal catheter revisions reduce the rate of subsequent revisions in pediatric patients operated for hydrocephalus","authors":"Brigitta Balogh, F. Rárosi, T. Kovács","doi":"10.4103/jpn.jpn_61_21","DOIUrl":"https://doi.org/10.4103/jpn.jpn_61_21","url":null,"abstract":"","PeriodicalId":46746,"journal":{"name":"Journal of Pediatric Neurosciences","volume":"1 1","pages":""},"PeriodicalIF":0.5,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70820227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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