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Connecting DSM-5 and ICD-11 trait domains with schema therapy and dialectical behavior therapy constructs. 将DSM-5和ICD-11特征域与图式治疗和辩证行为治疗结构联系起来。
IF 2.7 3区 医学 Q1 Nursing Pub Date : 2023-08-01 Epub Date: 2022-12-27 DOI: 10.1002/pmh.1574
Mikaela Tracy, Louise Sharpe, Bo Bach, Niko Tiliopoulos

The DSM-5 Section III alternative model of personality disorder (AMPD) and the International Classification of Diseases - 11th Edition's (ICD-11) personality disorder classification allow clinicians to identify individual trait domains in which people score highly. However, how these domains relate to constructs associated with efficacious treatment approaches is unclear. The current study aimed to determine whether constructs from two evidence-based treatments (schema therapy [ST] and dialectical behavior therapy [DBT]) were associated with maladaptive personality traits in a way consistent with underlying theories. We examined associations between ST constructs, DBT skill use and maladaptive coping styles, and personality traits in a sample of 525 adults. Bivariate intercorrelations and a series of multiple regression analyses were conducted to investigate the associations. As hypothesized, maladaptive coping was strongly associated with all trait domains. Surprisingly, poor DBT-skill use was only associated with negative affectivity, detachment, and disinhibition trait domains. Specific schema domains were associated with each personality trait domain, supporting trait domain-schema domain specificity. The current study highlights the potential clinical utility of the AMPD and ICD-11 trait models and ultimately contributes to the dearth of evidence on their likely usefulness for treatment selection, planning, and applications.

DSM-5第三节人格障碍替代模型(AMPD)和国际疾病分类-第11版(ICD-11)人格障碍分类使临床医生能够识别人们得分较高的个人特征领域。然而,这些领域如何与有效治疗方法相关的结构相关尚不清楚。目前的研究旨在确定两种循证治疗(模式疗法[ST]和辩证行为疗法[DBT])的结构是否与适应不良的人格特征相关,其方式与基础理论一致。我们在525名成年人的样本中研究了ST结构、DBT技能使用和适应不良的应对方式以及性格特征之间的关系。进行了双变量相互关联和一系列多元回归分析来研究这些关联。正如假设的那样,适应不良的应对与所有特质领域都密切相关。令人惊讶的是,DBT技能使用不佳只与消极情感、超然和去抑制特征域有关。特定的图式域与每个人格特质域相关联,支持特质域图式域的特异性。目前的研究强调了AMPD和ICD-11特征模型的潜在临床实用性,并最终导致缺乏证据表明它们可能对治疗选择、计划和应用有用。
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引用次数: 2
Associations between physical health and the alternative model of personality disorders: A cross-sectional age study. 身体健康与人格障碍替代模式之间的关系:一项横断面年龄研究。
IF 2.7 3区 医学 Q1 Nursing Pub Date : 2023-08-01 Epub Date: 2023-01-20 DOI: 10.1002/pmh.1576
Lisa E Stone, Daniel L Segal

The Alternative Model of Personality Disorders (AMPD) is a relatively new dimensional model of personality disorders (PDs) that assesses two diagnostic constructs: personality functioning and pathological personality traits. Thus far, research on the AMPD among older adults has been limited, but the research that does exist suggests limited generalizability to the unique biopsychosocial context of later life. To further examine the applicability of the AMPD to older adults, the purpose of this study was to examine relationships between the AMPD's two constructs with perceived physical health status among younger and older adult samples. Older adults (n = 222) and younger adults (n = 215) completed the Short Form-36 (SF-36), Levels of Personality Functioning Scale-Self-Report (LPFS-SR), and Personality Inventory for DSM-5-Brief Form (PID-5-BF). Correlations and Fisher's z-tests revealed significantly stronger relationships between the SF-36 with the LPFS-SR and PID-5-BF domains for older adults than younger adults. Additionally, age group significantly moderated the relationships between personality functioning and pathological personality traits and health. The stronger relationships between health and the AMPD's constructs for older adults suggest meaningful overlap between negative health outcomes and PD pathology. Future research should further investigate specific mechanisms in which personality pathology negatively impacts health in older adults.

人格障碍替代模型(AMPD)是一种相对较新的人格障碍维度模型,评估两种诊断结构:人格功能和病理性人格特征。到目前为止,对老年人AMPD的研究是有限的,但现有的研究表明,对晚年独特的生物心理社会背景的可推广性有限。为了进一步检验AMPD对老年人的适用性,本研究的目的是检验AMPD的两个结构与年轻人和老年人样本中感知的身体健康状况之间的关系。老年人(n = 222)和年轻人(n = 215)完成了简表-36(SF-36)、人格功能水平量表自评量表(LPFS-SR)和DSM-5简表人格量表(PID-5-BF)。相关性和Fisher z检验显示,与年轻人相比,老年人的SF-36与LPFS-SR和PID-5-BF结构域之间的关系明显更强。此外,年龄组显著调节了人格功能与病理性人格特征和健康之间的关系。老年人的健康和AMPD结构之间更强的关系表明,负面健康结果和PD病理之间有意义的重叠。未来的研究应该进一步调查人格病理学对老年人健康产生负面影响的具体机制。
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引用次数: 0
The influence of NOS1AP gene polymorphisms and childhood abuse on antisocial personality disorder in Chinese male violent inmates. NOS1AP基因多态性与童年虐待对中国男性暴力犯反社会人格障碍的影响
IF 2.7 3区 医学 Q1 Nursing Pub Date : 2023-05-01 DOI: 10.1002/pmh.1572
Jinyang Li, Lichen Ouyang, Xinyao Liu, Qiuyu Wang, Zhang Min, Gang Liu, Yuan Zhong, Ning Zhang, Chun Wang, Na Liu

Antisocial personality disorder (ASPD) is a common behavioral pattern that causes sufferers to ignore or violate the rights of others. Though its cause is still unclear, previous studies have shown that childhood maltreatment is closely related to ASPD. The NOS1AP gene is associated with various neuropsychiatric diseases, but a linkage between it and ASPD has not yet been discovered. This study recruited ASPD and non-ASPD male subjects who had committed violent crimes from a prison in Nanjing, China. By comparing the two groups' genotypes, allele frequencies, and histories of childhood abuse, we explored the interaction between the NOS1AP gene and childhood maltreatment on the pathogenesis of ASPD. The results showed that polymorphism rs945713 in the NOS1AP gene was associated with ASPD and furthermore that this SNP may be involved in regulating the effect of childhood abuse on ASPD. This study found that childhood trauma increases the risk of ASPD in violent adult male inmates; for prisoners with ASPD, it is critical to pay attention to their childhood trauma and take early psychological intervention.

反社会人格障碍(ASPD)是一种常见的行为模式,导致患者忽视或侵犯他人的权利。虽然其原因尚不清楚,但先前的研究表明,儿童虐待与反社会障碍密切相关。NOS1AP基因与多种神经精神疾病有关,但它与反社会人格障碍之间的联系尚未被发现。本研究在中国南京的一所监狱中招募了有过暴力犯罪行为的反社会人格障碍和非反社会人格障碍男性受试者。通过比较两组的基因型、等位基因频率和儿童虐待史,探讨NOS1AP基因与儿童虐待在反社会人格障碍发病机制中的相互作用。结果表明,NOS1AP基因rs945713多态性与ASPD相关,且该SNP可能参与调节童年虐待对ASPD的影响。该研究发现,童年创伤增加了暴力成年男性囚犯患反社会障碍的风险;对于患有反社会人格障碍的在押人员,关注其童年创伤,及早进行心理干预至关重要。
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引用次数: 0
Mapping established psychopathology scales onto the Hierarchical Taxonomy of Psychopathology (HiTOP). 将已建立的精神病理学量表映射到精神病理学层次分类(HiTOP)上。
IF 2.7 3区 医学 Q1 Nursing Pub Date : 2023-05-01 DOI: 10.1002/pmh.1566
Leon P Wendt, Kristin Jankowsky, Ulrich Schroeders, Tobias Nolte, Peter Fonagy, P Read Montague, Johannes Zimmermann, Gabriel Olaru

The Hierarchical Taxonomy of Psychopathology (HiTOP) organizes phenotypes of mental disorder based on empirical covariation, offering a comprehensive organizational framework from narrow symptoms to broader patterns of psychopathology. We argue that established self-report measures of psychopathology from the pre-HiTOP era should be systematically integrated into HiTOP to foster cumulative research and further the understanding of psychopathology structure. Hence, in this study, we mapped 92 established psychopathology (sub)scales onto the current HiTOP working model using data from an extensive battery of self-report assessments that was completed by community participants and outpatients (N = 909). Content validity ratings of the item pool were used to select indicators for a bifactor-(S-1) model of the p factor and five HiTOP spectra (i.e., internalizing, thought disorder, detachment, disinhibited externalizing, and antagonistic externalizing). The content-based HiTOP scales were validated against personality disorder diagnoses as assessed by standardized interviews. We then located established scales within the taxonomy by estimating the extent to which scales reflected higher-level HiTOP dimensions. The analyses shed light on the location of established psychopathology scales in HiTOP, identifying pure markers and blends of HiTOP spectra, as well as pure markers of the p factor (i.e., scales assessing mentalizing impairment and suspiciousness/epistemic mistrust).

《精神病理学层次分类法》(HiTOP)基于经验共变对精神障碍的表型进行了组织,提供了一个从狭窄症状到更广泛的精神病理学模式的综合组织框架。我们认为,在HiTOP之前建立的精神病理学自我报告测量应该系统地整合到HiTOP中,以促进累积研究并进一步了解精神病理学结构。因此,在本研究中,我们利用社区参与者和门诊患者(N = 909)完成的大量自我报告评估数据,将92个已建立的精神病理学(亚)量表映射到当前的HiTOP工作模型上。项目池的内容效度评分用于选择p因子的双因子-(S-1)模型和五个HiTOP谱(即内化、思维障碍、脱离、去抑制外化和对抗性外化)的指标。基于内容的HiTOP量表通过标准化访谈对人格障碍诊断进行了验证。然后,我们通过估计尺度反映高级HiTOP维度的程度,在分类法中定位已建立的尺度。分析揭示了HiTOP中已建立的精神病理量表的位置,确定了HiTOP谱的纯标记和混合标记,以及p因子的纯标记(即评估精神障碍和怀疑/认知不信任的量表)。
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引用次数: 2
Late manifestation of borderline personality disorder: Characterization of an under-recognized phenomenon. 边缘型人格障碍的晚期表现:一种未被认识的现象的特征。
IF 2.7 3区 医学 Q1 Nursing Pub Date : 2023-05-01 DOI: 10.1002/pmh.1571
Rachel Jo, Jillian H Broadbear, Judith Hope, Sathya Rao

Although uncommon, borderline personality disorder (BPD) may manifest for the first time later in life. A retrospective clinical file audit was used to identify the clinical manifestation of BPD for the first time at or above the age of 30, and to examine whether particular clinical and psychosocial factors may be associated with a later-in-life manifestation of BPD. Twenty-three cases of late manifestation BPD were identified. People with late manifestation of BPD had similar risk factors and vulnerabilities, including childhood trauma, to the broader BPD population. They were distinguished by having higher levels of education, employment, and long-term intimate relationships. Interpersonal problems, loss of employment and reminders of past sexual trauma were key precipitating factors. The findings underscore the legitimacy of a late-manifestation diagnosis of BPD by demonstrating that BPD does not present exclusively during adolescence and early adulthood. BPD may present for the first time in later life in response to loss of protective factors or triggering of past trauma. This understanding may reduce misdiagnosis or delayed diagnosis, prescription of inappropriate treatments or delays in receiving BPD-appropriate treatments.

虽然不常见,边缘型人格障碍(BPD)可能在以后的生活中首次出现。回顾性临床档案审核用于确定30岁或以上首次出现BPD的临床表现,并检查特定的临床和社会心理因素是否可能与BPD的后期表现相关。发现23例晚期表现的BPD。晚期BPD患者与更广泛的BPD人群具有相似的风险因素和脆弱性,包括童年创伤。他们的特点是教育水平、就业水平和长期的亲密关系都较高。人际关系问题、失业和对过去性创伤的回忆是主要的诱发因素。研究结果强调了BPD晚期诊断的合法性,表明BPD并不仅仅出现在青春期和成年早期。BPD可能在晚年首次出现,是对保护因素丧失或过去创伤触发的反应。这种认识可以减少误诊或延误诊断,处方不适当的治疗或延迟接受bpd适当的治疗。
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引用次数: 0
Stalking perpetration through the lens of the alternative DSM-5 model for personality disorders. 通过另一种人格障碍的DSM-5模型的镜头跟踪犯罪。
IF 2.7 3区 医学 Q1 Nursing Pub Date : 2023-05-01 DOI: 10.1002/pmh.1567
Dominick Gamache, Marie-Ève Cloutier, Jonathan Faucher, Philippe Leclerc, Claudia Savard

Emerging dimensional models of personality disorders such as the Alternative DSM-5 Model for Personality Disorders (AMPD) provide new opportunities to explore the associations between personality pathology and harmful interpersonal behaviours such as stalking perpetration. Two goals are pursued by this study: (a) To document associations between stalking, level of personality pathology, and pathological personality domains/facets; and (b) to determine the relative importance of maladaptive personality facets in the statistical prediction of stalking. Data from 1489 young adults (18-30 years old) from a community sample were analysed. Moderate positive significant correlations were found between stalking, level of personality pathology, and maladaptive personality domains. A clear gradient of severity of stalking behaviours was found across five severity degrees of personality pathology. Dominance analyses revealed that Deceitfulness was the most dominant statistical predictor in women. Unusual Beliefs and Experiences, a facet from the Psychoticism domain, made an important contribution in the prediction of stalking in men only. Impulsivity was a key predictor in both genders but more markedly in men. Results suggest that the AMPD represents a useful framework to study stalking perpetration. Identification of key personality predictors might prove relevant for identifying risk factors, underlying motives, and treatment targets for stalking perpetrators.

新兴的人格障碍维度模型,如DSM-5人格障碍替代模型(AMPD),为探索人格病理与有害人际行为(如跟踪犯罪)之间的关系提供了新的机会。本研究的两个目的是:(a)记录跟踪、人格病理水平和病态人格领域/方面之间的联系;(b)确定不适应人格因素在跟踪行为统计预测中的相对重要性。分析了来自社区样本的1489名年轻人(18-30岁)的数据。跟踪行为、人格病理水平和适应不良人格域之间存在中度显著正相关。跟踪行为的严重程度在人格病理的五个严重程度中有明显的梯度。优势分析显示,欺骗是女性最主要的统计预测因素。不寻常的信念和经历,来自精神病学领域的一个方面,在预测男性跟踪行为方面做出了重要贡献。冲动在两性中都是一个关键的预测因素,但在男性中更为明显。结果表明,AMPD是研究跟踪行为的一个有用的框架。关键人格预测因素的识别可能与识别跟踪犯罪者的风险因素、潜在动机和治疗目标有关。
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引用次数: 1
Influence of personality traits, gender, and socio-economic factors in obesity in the English Longitudinal Study of Ageing. 英国老龄化纵向研究中人格特征、性别和社会经济因素对肥胖的影响
IF 2.7 3区 医学 Q1 Nursing Pub Date : 2023-05-01 DOI: 10.1002/pmh.1575
Modou Diop, Manuel Ruiz-Adame, Alessio Gaggero

Obesity is a chronic disorder associated with high mortality rates and high morbidity. The risk of obesity is associated with certain personality traits (PTs). Some studies have found correlations among some PTs and gender. Additionally, obesity implies higher costs in daily living. The aim of this paper is to overcome this problem in the literature and estimate the association between PTs and obesity by taking into account the economic situation of the individual. This study employs data from the English Longitudinal Study of Ageing (ELSA). We focus on waves 5 and 6 of the ELSA with a sample of 6562 individuals. The results suggests that the traits of agreeableness ( β = 0.071 , se = 0.016 , p < 0.001 ) and openness ( β = 0.028 , se : 0.014 , p < 0.001 ) are positively and significantly associated with obesity. On the other hand, consciousness has a negative and statistically significant effect on obesity β = 0.072 , se : 0.017 , p < 0.001 . Results are robust to the inclusion/exclusion of different regressors.

肥胖是一种与高死亡率和高发病率相关的慢性疾病。肥胖的风险与某些人格特征(PTs)有关。一些研究发现了一些PTs与性别之间的相关性。此外,肥胖意味着日常生活成本更高。本文的目的是克服文献中的这一问题,并通过考虑个体的经济状况来估计PTs与肥胖之间的关联。本研究采用了英国老龄化纵向研究(ELSA)的数据。我们以6562个人为样本,重点研究ELSA的第5和第6波。结果表明,亲和性(β = 0.071, se = 0.016, p 0.001)和开放性(β = 0.028, se: 0.014, p 0.001)与肥胖呈显著正相关。另一方面,意识对肥胖有负的、有统计学意义的影响β = 0.072, se: 0.017, p 0.001。结果对不同回归量的纳入/排除是稳健的。
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引用次数: 0
Borderline personality disorder symptoms in individuals with eating disorder: Association with severity, psychological distress, and psychosocial function. 进食障碍患者的边缘性人格障碍症状:与严重程度、心理困扰和社会心理功能的关系
IF 2.7 3区 医学 Q1 Nursing Pub Date : 2023-05-01 DOI: 10.1002/pmh.1565
Prudence Vivarini, Zoe M Jenkins, David J Castle, Karen Gwee

We aimed to determine the prevalence of borderline personality disorder (BPD) symptoms in a sample of eating disorder (ED) outpatients and assess how BPD symptoms correlate with severity, distress, and function. A total of 119 individuals were assessed and divided into high BPD symptoms (H-BPD) and low BPD symptoms (L-BPD) using a cut-off score of seven on the McLean Screening for Borderline Personality Disorder (MSI-BPD). Groups were compared on ED diagnosis, age at ED onset, age at assessment, illness duration, body mass index (BMI), ED symptomatology, psychological distress, and psychosocial function. Correlation analyses were performed to assess the relationship between BPD symptoms and these variables. The 45.4% of the participants scored ≥7 on the MSI-BPD, indicating a diagnosis of BPD. There were no differences between the H-BPD (N = 54) and L-BPD (N = 65) groups on age at onset, age at assessment, duration of illness, BMI, or proportion of ED diagnosis. The H-BPD group reported significantly higher ED symptomatology, psychological distress, and poorer psychosocial functioning. MSI-BPD scores were positively associated with these variables. This study suggests a high prevalence of BPD symptoms within outpatients seeking ED treatment, and use of a brief screening instrument for BPD in this group may contribute to a greater understanding of the patient.

我们的目的是确定边缘性人格障碍(BPD)症状在进食障碍(ED)门诊患者样本中的患病率,并评估BPD症状与严重程度、痛苦和功能之间的关系。采用麦克林边缘型人格障碍筛查(MSI-BPD)的分值为7分,共对119人进行了评估,并将其分为高BPD症状(H-BPD)和低BPD症状(L-BPD)。各组患者在ED诊断、ED发病年龄、评估年龄、病程、体重指数(BMI)、ED症状、心理困扰和心理社会功能方面进行比较。进行相关分析以评估BPD症状与这些变量之间的关系。45.4%的参与者在MSI-BPD上得分≥7分,表明诊断为BPD。H-BPD组(N = 54)和L-BPD组(N = 65)在发病年龄、评估年龄、疾病持续时间、BMI或ED诊断比例方面没有差异。H-BPD组报告了明显更高的ED症状、心理困扰和更差的社会心理功能。MSI-BPD评分与这些变量呈正相关。本研究表明,在寻求ED治疗的门诊患者中,BPD症状的患病率很高,在这一群体中使用简短的BPD筛查工具可能有助于更好地了解患者。
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引用次数: 2
Normative data for the LPFS-BF 2.0 derived from the Danish general population and relationship with psychosocial impairment. LPFS-BF 2.0的标准数据来自丹麦普通人群及其与社会心理障碍的关系。
IF 2.7 3区 医学 Q1 Nursing Pub Date : 2023-05-01 DOI: 10.1002/pmh.1570
Laura C Weekers, Martin Sellbom, Joost Hutsebaut, Sebastian Simonsen, Bo Bach

The Level of Personality Functioning Scale-Brief Form 2.0 is a frequently used self-report inventory that may be used to screen for self- and interpersonal dysfunction according to the DSM-5 Alternative Model for Personality Disorders (AMPD) and the ICD-11 Classification of Personality Disorders. Nevertheless, reliable norms and cut-off scores to aid interpretation and clinical decision making are still lacking. The LPFS-BF and relevant impairment measures were administered to a sociodemographically stratisfied sample of 2,002 adults from the general Danish population of whom 713 individuals eventually delivered data for inclusion in the present study. The unidimensionality of the LPFS-BF scores was established using Confirmatory Factor Analysis (CFA). Item-Response Theory (IRT) analysis indicated satisfactory item functioning for all 12 items and suggested normative observed score thresholds at different latent severity levels. Meaningful associations were found between the LPFS-BF norm-based cut-off scores, quality of life, and social and occupational functioning. This study presented the first normative data for LPFS-BF, which specifically applies to Denmark but likely also other socioeconomically comparable Nordic and Western societies. These results allow for interpretation of LPFS-BF scores and clinical decision-making. Future research should corroborate these findings and compare them to scores obtained in other general population samples.

根据DSM-5人格障碍替代模型(AMPD)和ICD-11人格障碍分类,人格功能水平量表-简表2.0是一种常用的自我报告清单,可用于筛选自我和人际功能障碍。然而,仍然缺乏可靠的标准和临界值来帮助解释和临床决策。LPFS-BF和相关损伤测量对来自丹麦普通人群的2002名成年人进行了社会人口统计学分层样本,其中713人最终提供了纳入本研究的数据。采用验证性因子分析(CFA)确定LPFS-BF评分的单维性。项目反应理论(IRT)分析表明,所有12个项目的项目功能都令人满意,并提出了不同潜在严重程度的规范观察得分阈值。在LPFS-BF基于规范的分值、生活质量、社会和职业功能之间发现了有意义的关联。这项研究提出了LPFS-BF的第一个规范性数据,它特别适用于丹麦,但可能也适用于其他社会经济可比较的北欧和西方社会。这些结果可以解释LPFS-BF评分和临床决策。未来的研究应证实这些发现,并将其与其他一般人群样本的得分进行比较。
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引用次数: 5
Are physical activity and nutrition linked to personality disorders? Health habits and personality disorders: A scoping review. 体育活动和营养与人格障碍有关吗?健康习惯与人格障碍:范围综述。
IF 2.7 3区 医学 Q1 Nursing Pub Date : 2023-05-01 DOI: 10.1002/pmh.1568
Samuel St-Amour, Félix-Antoine Bérubé, Lionel Cailhol, Catherine Le Corff

Individuals with personality disorders (PDs) have a decreased life expectancy compared with the general population in part due to physical illnesses. Many hypotheses have been suggested to explain those physical illnesses such as hormone imbalance, medication, lack of physical activity, and unhealthy diet. However, little is known about the relation between lifestyle and PDs. The purpose of this scoping review is to regroup the available information on this topic. We searched the literature up to February 2021 using four databases and found 21 articles analyzing the relation between lifestyle and PDs in observational studies including 153,081 participants from diverse populations going from general population to adults in psychiatric care. Most studies used measures of lifestyle as control variables or did not use lifestyle variables at all. Moreover, the instruments used to measure lifestyle variables lacked precision at best. Two studies demonstrated a relation between early malnutrition and further development of PDs, but those results may be influenced by confounding variables and cannot indicate a clear link between nutrition and personality disorder. The lack of solid evidence we observed is surprising, considering the multiple benefits individuals with PDs could get from a healthy lifestyle. More studies are needed to thoroughly analyze the impact of lifestyle on PDs and vice versa.

与一般人群相比,人格障碍(pd)患者的预期寿命较短,部分原因是身体疾病。人们提出了许多假说来解释这些身体疾病,如激素失衡、药物、缺乏体育活动和不健康的饮食。然而,人们对生活方式与pd之间的关系知之甚少。这个范围审查的目的是重新组合关于这个主题的可用信息。我们使用四个数据库检索了截至2021年2月的文献,并在观察性研究中发现了21篇分析生活方式与pd之间关系的文章,其中包括来自不同人群的153,081名参与者,从普通人群到精神科护理的成年人。大多数研究使用生活方式作为控制变量,或者根本不使用生活方式变量。此外,用于测量生活方式变量的仪器充其量也不够精确。两项研究表明,早期营养不良与pd的进一步发展之间存在联系,但这些结果可能受到混杂变量的影响,无法表明营养与人格障碍之间存在明确的联系。考虑到患有pd的人可以从健康的生活方式中获得多种好处,我们观察到的缺乏确凿证据令人惊讶。需要更多的研究来彻底分析生活方式对pd的影响,反之亦然。
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引用次数: 1
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Personality and Mental Health
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