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Knowledge of Preconception Care and Associated Factors among Healthcare Providers Working in Public Health Institutions in Awi Zone, North West Ethiopia, 2019: Institutional-Based Cross-Sectional Study 2019年埃塞俄比亚西北部Awi地区公共卫生机构医护人员孕前护理知识及相关因素:基于机构的横断面研究
IF 3.2 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2020-04-14 DOI: 10.1155/2020/6978171
Mahlet Million Bekele, N. Gebeyehu, Mezgebu Mihret Kefale, Simachew Animen Bante
Background. Preconception care is a set of interventional care for the better maternal and childbirth outcome. Nevertheless, this area still faces implementation problems in most of the developing countries including Ethiopia. Objective. To assess the knowledge of preconception care and associated factors among healthcare providers working in public health institutions in Awi zone, North West Ethiopia. Method. An institutional-based cross-sectional study was conducted among 660 healthcare providers working in public health institutions in Awi zone, North West Ethiopia. A pretested structured self-administered questionnaire was used to collect the data from individual healthcare providers who were selected randomly using a multistage sampling technique. The data entry and analysis were conducted using SPSS version 25 software. Frequency, proportions, means, and standard deviations were used to describe the data. Candidate variables at bivariate logistic regression with a p value > 0.2 were moved to multivariable logistic regression models, and statistical significance was declared at p value < 0.05 with 95% confidence interval. Result. Among the total of 660 healthcare providers, 344 (52%) had good knowledge of preconception care. The odds ratio of having good knowledge of preconception care was high among healthcare providers working at hospitals [AOR = 2:316, 95% CI: 1.900-5.528], using smartphones [AOR = 3:177, 95% CI: 1.945-5.167], presence of preconception care guidelines at health institutions [AOR = 3:166, 95% CI: 1.872-5.299], taking training on preconception care education and counseling [AOR = 3:812, 95% CI: 2.241-6.581], taking training about human immune virus [AOR = 4:911, 95% CI: 3.0088.123], and attending training on increasing public awareness of preconception health and care [AOR = 2:345, 95% CI: 3.9225.488] which were independent predictors associated with knowledge of preconception care among healthcare providers. Conclusion. Healthcare providers’ knowledge of preconception care was low. Study participants working at hospitals, using smartphones, presence of preconception guidelines at health institutions, taking training on preconception education and counseling, taking training about human immune virus testing and management, and increasing public awareness of preconception care affect knowledge of health providers positively. The provision of updated training on preconception and linkage of internet service with health service should be enhanced among healthcare providers.
背景孕前护理是一套为获得更好的孕产妇和分娩结果而进行的干预性护理。尽管如此,这一领域在包括埃塞俄比亚在内的大多数发展中国家仍然面临执行问题。客观的评估在埃塞俄比亚西北部Awi地区公共卫生机构工作的医疗保健提供者对先入为主护理和相关因素的了解。方法一项基于机构的横断面研究在埃塞俄比亚西北部Awi地区公共卫生机构的660名医疗保健提供者中进行。采用预先测试的结构化自填问卷从使用多阶段抽样技术随机选择的个体医疗保健提供者那里收集数据。数据录入和分析采用SPSS 25版软件进行。使用频率、比例、平均值和标准偏差来描述数据。将p值>0.2的双变量逻辑回归中的候选变量转移到多变量逻辑回归模型中,并在p值<0.05时宣布统计学显著性,置信区间为95%。后果在660名医疗保健提供者中,344人(52%)对孕前护理有很好的了解。在医院工作的医疗保健提供者中,对先入为主护理有良好了解的比值比很高[AOR=2:316,95%CI:1.900-5.528],使用智能手机[AOR=3:177,95%CI:1.945-5.167],在卫生机构存在先入为主保健指南[AOR=3:366,95%CI:1.872-5.299],接受孕前保健教育和咨询培训[AOR=3:812,95%CI:2.241-6.581],接受人类免疫病毒培训[AOR=4:911,95%CI:3.0088.123],以及参加关于提高公众对先入为主的健康和护理意识的培训[AOR=2:345,95%CI:3.9225.488],这是与医疗保健提供者的先入为主护理知识相关的独立预测因素。结论医疗保健提供者对先入为主护理的了解程度较低。研究参与者在医院工作、使用智能手机、在卫生机构提供先入为主的指导方针、接受先入为主教育和咨询培训、接受人体免疫病毒检测和管理培训,以及提高公众对先入为主护理的认识,都会对卫生服务提供者的知识产生积极影响。应加强在医疗保健提供者中提供关于互联网服务与医疗保健服务的先入为主和联系的最新培训。
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引用次数: 9
Physical Effects of Maternal Deaths on Midwives' Health: A Qualitative Approach. 产妇死亡对助产士健康的影响:定性方法。
IF 3.2 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2020-04-01 eCollection Date: 2020-01-01 DOI: 10.1155/2020/2606798
Anita Fafa Dartey, Ellemes Phuma-Ngaiyaye

Grief does not only affect human emotions but also impacts their physical health. Understanding physical grief of people can bring to bear the grip of its daunting nature, a situation where routines become challenging. A qualitative explorative descriptive research method was used. A purposive sample of 18 ward supervisors and 39 ward midwives was used to ascertain the physical effects of maternal deaths on these caregivers in the Ashanti Region of Ghana. Data were collected through semistructured and focus group discussions. Data analysis was done parallel with data collection till saturation was reached. Ethics was obtained from the University of the Western Cape, South Africa, and Ghana Health Service. The findings indicated that generally, as a result of grieving over the deaths of their patients, midwives experienced physical health sufferings. Therefore, reported depression is expressed as insomnia, appetite loss, exhaustion, and social isolation. There is the need to reduce the physical effects of patients' death on caregivers in Ghana and therefore, the study recommends that all hospitals in Ghana utilize employee assistance programmes, a workplace intervention programme designed for such purposes.

悲伤不仅会影响人的情绪,还会影响人的身体健康。了解人们身体上的悲痛,可以让人感受到其令人生畏的性质,这种情况下,日常工作变得具有挑战性。本研究采用了定性探索描述性研究方法。对加纳阿散蒂地区的 18 名病房主管和 39 名病房助产士进行了有目的的抽样调查,以确定孕产妇死亡对这些护理人员身体的影响。数据是通过半结构式讨论和焦点小组讨论收集的。数据分析与数据收集同时进行,直至达到饱和。研究获得了南非西开普大学和加纳卫生局的伦理许可。研究结果表明,一般来说,由于对病人的死亡感到悲伤,助产士的身体健康会受到影响。因此,报告的抑郁症表现为失眠、食欲不振、疲惫和社交孤立。有必要减少病人死亡对加纳护理人员身体的影响,因此,研究建议加纳所有医院利用员工援助计划,这是一项为此目的而设计的工作场所干预计划。
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引用次数: 0
Associated Factors of Postpartum Modern Contraceptive Use in Burie District, Amhara Region, Ethiopia. 埃塞俄比亚阿姆哈拉地区 Burie 县产后使用现代避孕药具的相关因素。
IF 3.2 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2020-03-21 eCollection Date: 2020-01-01 DOI: 10.1155/2020/6174504
Wassachew Ashebir, Tilahun Tadesse

Methods: A community-based cross-sectional study was employed among 686 mothers in Burie District from March 16 to March 25, 2017. A multistage sampling technique was used to select the study participants. Data were collected using face to face interviewer administered structured questionnaires. Then, the collected data was entered, coded, and cleaned into EPI Data version 3.1 and exported to SPSS version 20.0 for data analysis. Bivariate and multivariate logistic regression was done to assess the association of factors with postpartum modern contraceptive use. Adjusted odds ratios with 95% confidence intervals were calculated, and p values <0.05 were considered to indicate statistical significance.

Result: This study revealed that postpartum modern contraceptive use was found to be 20.7%. Postpartum modern contraceptive use was significantly associated with women's level of education (AOR = 0.15, 95% CI (0.03-0.71)), discussing FP methods with partner (AOR = 0.60, 95% CI (0.40-0.90)), knowing menses return after birth (AOR = 0.39, 95% CI (0.25-0.59)), ever heard about modern FP methods (AOR = 0.06, 95% CI (0.01-0.43)), and contacting health professionals (AOR = 1.85, 95% CI (1.19-2.88)). Conclusion and Recommendations. Postpartum modern contraceptive use was found to be low. Therefore, health professionals should work on improvements in women's educational status, making awareness of the women and counseling of their husbands about the use of postpartum contraception, when fertility returned and risky timing for becoming pregnant.

研究方法2017年3月16日至3月25日,在布里区的686名母亲中开展了一项基于社区的横断面研究。研究采用多阶段抽样技术挑选参与者。数据收集采用面对面访谈的结构化问卷。然后,将收集到的数据输入 EPI Data 3.1 版进行编码和清理,并导出到 SPSS 20.0 版进行数据分析。通过二元和多元逻辑回归评估了各因素与产后使用现代避孕药具的关系。计算了调整后的几率比和 95% 的置信区间,并得出了 p 值:研究显示,产后使用现代避孕药具的比例为 20.7%。产后现代避孕药具的使用与妇女的受教育程度(AOR = 0.15,95% CI (0.03-0.71))、与伴侣讨论 FP 方法(AOR = 0.60,95% CI (0.40-0.90))、知道月经复潮(AOR = 0.60,95% CI (0.03-0.71))、与伴侣讨论 FP 方法(AOR = 0.60,95% CI (0.40-0.90)90)、知道产后月经会恢复(AOR = 0.39,95% CI (0.25-0.59))、听说过现代 FP 方法(AOR = 0.06,95% CI (0.01-0.43))以及联系过卫生专业人员(AOR = 1.85,95% CI (1.19-2.88))。结论与建议。产后现代避孕药具的使用率较低。因此,卫生专业人员应努力改善妇女的教育状况,提高妇女对产后避孕的认识,并向其丈夫提供有关产后避孕、恢复生育能力和怀孕风险时机的咨询。
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引用次数: 0
Factors That Determine the Likelihood of Giving Birth to the First Child within 10 Months after Marriage. 决定婚后10个月内生育第一个孩子可能性的因素。
IF 3.2 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2020-03-20 eCollection Date: 2020-01-01 DOI: 10.1155/2020/4675907
Abdul-Karim Iddrisu, Francis Kwame Bukari, Kwaku Opoku-Ameyaw, Gabriel Oppong Afriyie, Kassim Tawiah

Background: One of the major aims of marriage is to procreate or give birth to a child. Childbirth is so crucial in marriage that it often determines the happiness of the couple. Too much delay in childbirth after marriage or the likelihood that one cannot give birth after marriage can lead to divorce. However, causes of delay in childbirth are often difficult to detect by both the Gynaecologist and the couple involved. This makes proposing solutions to issues related to childbirth usually unsuccessful.

Methods: It is against this background that we conducted this study to identify factors that determine childbirth within 10 months or after 10 months of marriage (birth length) among women in Ghana. This was achieved by using a logistic regression model for the dichotomous birth length variable, adjusting for risk factors/predictors of birth length. The data used for the study were obtained from the 2014 Ghana Demographic and Health Survey, consisting 6,525 complete cases with 18 predictor variables. Statistical analyses were carried out using STATA version 14.1.

Results: The results show that respondents who have ever terminated pregnancy are more likely (OR = 0.178, 95%CI = 0.044, 0.312) to deliver after 10 months, wives whose husbands have higher education are less likely (OR = -0.162, 95%CI = -0.236, -0.088) to give birth after 10 months of marriage, wives who reported that beating is justified if she goes out without her husband's notice are more likely (OR = 0.466, 95%CI = 0.305, 0.628) to give birth after 10 months, wives who reported that beating is justified if she neglects the child are more likely (OR = -0.305, 95%CI = -0.461, -0.149) to give birth within 10 months, and wives who reported that beating is justified when she argues with her husband are less likely (OR = -0.301, 95%CI = -0.451, -0.152) to give birth after 10 months of marriage. Every unit increase in the age of the respondent at marriage increases the likelihood of giving birth after 10 months of marriage, and a unit increase in the age of the respondent at first sex decreases the likelihood of giving birth after 10 months in marriage.

Conclusions: For conception within 1 month of marriage, wives and husbands should/are encouraged to have frequent sex, any negative social behaviour or policies must be discouraged, experts' advice on contraceptive use must be sought, and women are encouraged to desist from termination of pregnancy at any time of their life. Husbands should openly express their desire and love for their children since this increases the likelihood of wives' desire to give birth. This leads to frequent sex, which then reduces conception time, and hence childbirth within the shortest possible time.

背景:婚姻的主要目的之一是生育孩子。生育在婚姻中是如此重要,它常常决定着夫妻的幸福。婚后生育太迟或婚后不能生育的可能性会导致离婚。然而,延迟分娩的原因往往很难被妇科医生和有关夫妇发现。这使得提出与生育有关的问题的解决方案通常不成功。方法:正是在这种背景下,我们进行了这项研究,以确定加纳妇女在结婚10个月内或结婚10个月后(生育长度)决定分娩的因素。这是通过使用二分出生长度变量的逻辑回归模型,调整出生长度的危险因素/预测因素来实现的。该研究使用的数据来自2014年加纳人口与健康调查,包括6525个完整病例和18个预测变量。使用STATA 14.1版本进行统计分析。结果:结果表明,曾经终止妊娠的被调查者在10个月后分娩的可能性更大(OR = 0.178, 95%CI = 0.044, 0.312),丈夫受过高等教育的妻子在结婚10个月后分娩的可能性更小(OR = -0.162, 95%CI = -0.236, -0.088),在丈夫未通知的情况下外出殴打是合理的妻子在10个月后分娩的可能性更大(OR = 0.466, 95%CI = 0.305, 0.628)。那些认为忽视孩子就有理由打孩子的妻子在10个月内分娩的可能性更大(OR = -0.305, 95%CI = -0.461, -0.149),而那些认为与丈夫争吵就有理由打孩子的妻子在结婚10个月后分娩的可能性更小(OR = -0.301, 95%CI = -0.451, -0.152)。被调查者结婚时的年龄每增加一个单位,结婚10个月后生育的可能性就会增加;被调查者初次性行为的年龄每增加一个单位,结婚10个月后生育的可能性就会减少。结论:对于婚后1个月内的受孕,应鼓励夫妻双方频繁发生性行为,不鼓励任何不良的社会行为和政策,应征求有关避孕药具使用的专家意见,并鼓励妇女在任何时候都不要终止妊娠。丈夫应该公开表达他们对孩子的渴望和爱,因为这增加了妻子想要生孩子的可能性。这导致频繁的性行为,从而减少受孕时间,从而在尽可能短的时间内分娩。
{"title":"Factors That Determine the Likelihood of Giving Birth to the First Child within 10 Months after Marriage.","authors":"Abdul-Karim Iddrisu,&nbsp;Francis Kwame Bukari,&nbsp;Kwaku Opoku-Ameyaw,&nbsp;Gabriel Oppong Afriyie,&nbsp;Kassim Tawiah","doi":"10.1155/2020/4675907","DOIUrl":"https://doi.org/10.1155/2020/4675907","url":null,"abstract":"<p><strong>Background: </strong>One of the major aims of marriage is to procreate or give birth to a child. Childbirth is so crucial in marriage that it often determines the happiness of the couple. Too much delay in childbirth after marriage or the likelihood that one cannot give birth after marriage can lead to divorce. However, causes of delay in childbirth are often difficult to detect by both the Gynaecologist and the couple involved. This makes proposing solutions to issues related to childbirth usually unsuccessful.</p><p><strong>Methods: </strong>It is against this background that we conducted this study to identify factors that determine childbirth within 10 months or after 10 months of marriage (birth length) among women in Ghana. This was achieved by using a logistic regression model for the dichotomous birth length variable, adjusting for risk factors/predictors of birth length. The data used for the study were obtained from the 2014 Ghana Demographic and Health Survey, consisting 6,525 complete cases with 18 predictor variables. Statistical analyses were carried out using STATA version 14.1.</p><p><strong>Results: </strong>The results show that respondents who have ever terminated pregnancy are more likely (OR = 0.178, 95%CI = 0.044, 0.312) to deliver after 10 months, wives whose husbands have higher education are less likely (OR = -0.162, 95%CI = -0.236, -0.088) to give birth after 10 months of marriage, wives who reported that beating is justified if she goes out without her husband's notice are more likely (OR = 0.466, 95%CI = 0.305, 0.628) to give birth after 10 months, wives who reported that beating is justified if she neglects the child are more likely (OR = -0.305, 95%CI = -0.461, -0.149) to give birth within 10 months, and wives who reported that beating is justified when she argues with her husband are less likely (OR = -0.301, 95%CI = -0.451, -0.152) to give birth after 10 months of marriage. Every unit increase in the age of the respondent at marriage increases the likelihood of giving birth after 10 months of marriage, and a unit increase in the age of the respondent at first sex decreases the likelihood of giving birth after 10 months in marriage.</p><p><strong>Conclusions: </strong>For conception within 1 month of marriage, wives and husbands should/are encouraged to have frequent sex, any negative social behaviour or policies must be discouraged, experts' advice on contraceptive use must be sought, and women are encouraged to desist from termination of pregnancy at any time of their life. Husbands should openly express their desire and love for their children since this increases the likelihood of wives' desire to give birth. This leads to frequent sex, which then reduces conception time, and hence childbirth within the shortest possible time.</p>","PeriodicalId":47062,"journal":{"name":"Journal of Pregnancy","volume":"2020 ","pages":"4675907"},"PeriodicalIF":3.2,"publicationDate":"2020-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2020/4675907","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37808606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Unintended Pregnancy and Associated Factors among Pregnant Women Attending Antenatal Care at Bako Tibe District Public Health Facility, Oromia Region, Ethiopia. 在埃塞俄比亚奥罗米亚地区Bako Tibe区公共卫生设施接受产前保健的孕妇中的意外怀孕及其相关因素
IF 3.2 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2020-03-19 eCollection Date: 2020-01-01 DOI: 10.1155/2020/3179193
Habtamu Bekele, Merga Dheressa, Bezatu Mengistie, Yitagesu Sintayehu, Gelana Fekadu

Background: A pregnancy is described unintended if it is either unwanted or mistimed. The former occurs when no child or no more children are desired, and the latter is when the conception occurs earlier than the desired time, but wanted later. Unwanted pregnancy causes a serious health, economic, and social problem to the woman and her family. In the study area, there is limited data on unintended pregnancy. Therefore, this study fills this gap by studying the magnitude of unintended pregnancy and its associated factors among pregnant women attending antenatal care in the study area.

Methods: A facility-based cross-sectional study was done from 1 March to 1 April 2019, among 612 randomly selected pregnant women attending antenatal care at Bako Tibe district public health facility. The data were collected via interview using a structured and pretested questionnaire. They were entered into EpiData Version 3.1 and SPSS Version 23 for cleaning and analyses. The variables, which were significant at P ≤ 0.2 in the bivariate logistic regression, were included in the multivariable analysis. The direction and strength of statistical association were measured by an odds ratio with 95% CI. A variable with a P value < 0.05 was considered a significantly associated factor with the outcome one.

Results: In this study, the prevalence of unintended pregnancy was 33.3%, at 95% CI (29.8, 37.3). The factors that had significant association with unintended pregnancy were family size ≥ 6 (AOR = 8.0, 95% CI: 1.38-46.66), women who did not communicate about family planning with their husbands (AOR = 2.8, 95% CI: 1.50-5.20), and parity ≥ 5 (AOR = 3.0, 95% CI: 1.34-6.8).

Conclusion: About one-third of the pregnant women reported that their pregnancy was unintended. Parity, family size, and lack of spousal communication showed a significant association with the problem. To decrease the current level of unintended pregnancy in the area, the Bako Tibe District Health Bureau and the health workers should work harder to scale up spousal communication on family planning.

背景:意外怀孕是指意外怀孕或不合时宜怀孕。前者发生在不想要孩子或不想要更多孩子的时候,后者发生在受孕早于想要的时间,但想要的时间更晚的时候。意外怀孕对妇女及其家庭造成严重的健康、经济和社会问题。在研究领域,关于意外怀孕的数据有限。因此,本研究通过研究本研究地区参加产前护理的孕妇意外怀孕的程度及其相关因素来填补这一空白。方法:2019年3月1日至4月1日,对在Bako Tibe区公共卫生机构接受产前保健的612名随机选择的孕妇进行了一项基于设施的横断面研究。数据是通过访谈收集的,使用结构化和预先测试的问卷。录入EpiData Version 3.1和SPSS Version 23进行清洗和分析。在双变量logistic回归中P≤0.2显著的变量纳入多变量分析。统计学关联的方向和强度采用95% CI的优势比来衡量。P值< 0.05的变量被认为是与结果显著相关的因素。结果:本研究中,意外妊娠发生率为33.3%,95% CI(29.8, 37.3)。与意外妊娠显著相关的因素为家庭人数≥6人(AOR = 8.0, 95% CI: 1.38 ~ 46.66)、未与丈夫沟通计划生育(AOR = 2.8, 95% CI: 1.50 ~ 5.20)、胎次≥5胎(AOR = 3.0, 95% CI: 1.34 ~ 6.8)。结论:约三分之一的孕妇报告其意外怀孕。性别平等、家庭规模和缺乏配偶沟通显示出与该问题的显著关联。为了降低该地区目前的意外怀孕水平,巴可藏区卫生局和卫生工作者应更加努力地扩大计划生育方面的配偶沟通。
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引用次数: 11
Early Pregnancy Serum Metabolite Profiles Associated with Hypertensive Disorders of Pregnancy in African American Women: A Pilot Study. 与非裔美国妇女妊娠期高血压疾病相关的孕早期血清代谢物谱:一项试点研究。
IF 3.2 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2020-02-19 eCollection Date: 2020-01-01 DOI: 10.1155/2020/1515321
Erin P Ferranti, Jennifer K Frediani, Rebecca Mitchell, Jolyn Fernandes, Shuzhao Li, Dean P Jones, Elizabeth Corwin, Anne L Dunlop

Hypertensive disorders of pregnancy (HDP) are the most common cardiometabolic complications of pregnancy, affecting nearly 10% of US pregnancies and contributing substantially to maternal and infant morbidity and mortality. In the US, women of African American race are at increased risk for HDP. Early biomarkers that reliably identify women at risk for HDP remain elusive, yet are essential for the early identification and targeting of interventions to improve maternal and infant outcomes. We employed high-resolution metabolomics (HRM) to identify metabolites and metabolic pathways that were altered in early (8-14 weeks) gestation serum samples of pregnant African American women who developed HDP after 20 weeks' gestation (n = 20)-either preeclampsia (PE; n = 11) or gestational hypertension (gHTN; n = 9)-compared to those who delivered full term without complications (n = 80). We found four metabolic pathways that were significantly (p < 0.05) altered in women who developed PE and five pathways that were significantly (p < 0.05) altered in women who developed gHTN compared to women who delivered full term without complications. We also found that four specific metabolites (p < 0.05) were distinctly upregulated (retinoate, kynurenine) or downregulated (SN-glycero-3-phosphocholine, 2'4'-dihydroxyacetophenone) in women who developed PE compared to gHTN. These findings support that there are systemic metabolic disruptions that are detectable in early pregnancy (8-14 weeks of gestation) among pregnant African American women who develop PE and gHTN. Furthermore, the early pregnancy metabolic disruptions associated with PE and gHTN are distinct, implying they are unique entities rather than conditions along a spectrum of the same disease process despite the common clinical feature of high blood pressure.

妊娠期高血压疾病(HDP)是最常见的妊娠期心脏代谢并发症,影响了近 10%的美国孕妇,并严重影响了母婴的发病率和死亡率。在美国,非裔美国妇女罹患妊娠高血压的风险更高。能可靠识别高危妊娠妇女的早期生物标志物仍然难以获得,但这对早期识别和有针对性地采取干预措施以改善母婴预后至关重要。我们采用高分辨率代谢组学(HRM)来鉴定妊娠早期(8-14 周)血清样本中发生变化的代谢物和代谢通路,这些样本来自妊娠 20 周后发生 HDP 的非裔美国孕妇(n = 20)--子痫前期(PE;n = 11)或妊娠高血压(gHTN;n = 9)--与足月分娩且无并发症的孕妇(n = 80)进行比较。我们发现,与无并发症的足月分娩妇女相比,发生 PE 的妇女有四种代谢途径发生了显著变化(p < 0.05),发生 gHTN 的妇女有五种代谢途径发生了显著变化(p < 0.05)。我们还发现,与发生 gHTN 的产妇相比,发生 PE 的产妇体内有四种特定代谢物(p < 0.05)明显上调(视黄酸、犬尿氨酸)或下调(SN-甘油-3-磷酸胆碱、2'4'-二羟基苯乙酮)。这些发现证明,在妊娠早期(妊娠 8-14 周),可检测到非裔美国孕妇发生 PE 和 gHTN 的全身代谢紊乱。此外,与 PE 和 gHTN 相关的孕早期代谢紊乱是不同的,这意味着它们是独特的实体,而不是同一疾病过程中的一种情况,尽管它们的共同临床特征是高血压。
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引用次数: 0
Solving the Obstetrical Paradox: The FETAL Technique-A Step toward Noninvasive Evaluation of Fetal pH. 解决产科悖论:FETAL 技术--向无创评估胎儿 pH 值迈出的一步。
IF 3.2 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2020-02-08 eCollection Date: 2020-01-01 DOI: 10.1155/2020/7801039
Jacques Balayla, Guy Shrem

Every year, about 85 percent of the approximately 5 million births in North America are evaluated with the electronic fetal monitoring (EFM). Clinicians use the EFM as a proxy to assess fetal oxygenation status, fetal well-being, and potential compromise. Despite the widespread use of this technology, neonatal hypoxia and acidosis continue to make up a high proportion of neonatal morbidity at term. Indeed, though the fetal heart rhythm is inextricably linked to fetal acid-base status, EFM has not been shown to reliably predict neonatal pH status nor has it reduced adverse maternal or neonatal outcomes. As a consequence, the high false-positive rate of EFM for predicting adverse neonatal outcomes has led to an increase in the rate of operative vaginal and cesarean delivery, with elevated rates of associated maternal and neonatal morbidity. This fact invariably leads to a paradox we have henceforth defined as the "obstetrical paradox." Herein, we explore the potential solutions to this paradox and introduce a novel noninvasive technique to assess fetal acid-base status in utero known as the "FETAL technique" (Fourier Evaluation of Tracings and Acidosis in Labour). The FETAL technique, currently under investigation, applies the discrete Fourier transformation to EFM tracings to determine the spectral frequency distribution of the fetal heart rate. These specific frequency distributions correlate with specific umbilical pH values and may provide the missing link between fetal heat rate patterns and acid-base status at birth. As we work toward realizing the full potential benefits of EFM, finding the best assessment strategies to evaluate fetal pH in real time remains a key goal in obstetrics.

每年,在北美约 500 万名新生儿中,约有 85% 接受电子胎儿监护(EFM)评估。临床医生使用电子胎儿监护仪来评估胎儿氧合状态、胎儿健康状况和潜在的损害。尽管这项技术已得到广泛应用,但新生儿缺氧和酸中毒仍占足月新生儿发病率的很高比例。事实上,虽然胎儿的心律与胎儿的酸碱状态密不可分,但 EFM 并未被证明能可靠地预测新生儿的 pH 值状态,也未减少孕产妇或新生儿的不良结局。因此,EFM 预测新生儿不良结局的高假阳性率导致了阴道和剖宫产手术率的增加,同时也增加了相关孕产妇和新生儿的发病率。这一事实必然导致一个悖论,我们将其定义为 "产科悖论"。在本文中,我们探讨了解决这一悖论的潜在方法,并介绍了一种评估宫内胎儿酸碱状态的新型无创技术,即 "FETAL 技术"(傅立叶产程描记和酸中毒评估)。目前正在研究的 FETAL 技术将离散傅立叶变换应用于 EFM 曲线,以确定胎儿心率的频谱频率分布。这些特定的频率分布与特定的脐带 pH 值相关,并可能提供胎儿热率模式与出生时酸碱状态之间缺失的联系。当我们努力实现 EFM 的全部潜在益处时,找到实时评估胎儿 pH 值的最佳评估策略仍是产科的关键目标。
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引用次数: 0
Early Pregnancy Screening for Women at High-Risk of GDM Results in Reduced Neonatal Morbidity and Similar Maternal Outcomes to Routine Screening. 妊娠早期筛查GDM高危妇女新生儿发病率降低,与常规筛查结果相似。
IF 3.2 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2020-01-29 eCollection Date: 2020-01-01 DOI: 10.1155/2020/9083264
Erin Clarke, Thomas J Cade, Shaun Brennecke

The Australasian Diabetes in Pregnancy Society recommends screening high-risk women for gestational diabetes mellitus (GDM) before 24 weeks gestation, under the assumption that an earlier diagnosis and opportunity to achieve normoglycemia will minimize adverse outcomes. However, little evidence exists for this recommendation. The study objective was to compare the pregnancy outcomes of high-risk women diagnosed with GDM before 24 weeks gestation and routinely diagnosed women after 24 weeks gestation. A retrospective audit was conducted of all pregnancies diagnosed with GDM using International Association of Diabetes and Pregnancy Study Groups criteria over 12 months at a tertiary Australian hospital. Adverse perinatal outcomes were compared between "Early GDM" diagnosed before 24 weeks (n = 133) and "Late GDM" diagnosed from 24 weeks (n = 636). Early GDM had a significantly lower newborn composite outcome frequency (hypoglycemia, birth trauma, NICU/SCN admission, stillbirth, neonatal death, respiratory distress, and phototherapy) compared to Late GDM (20.3% vs. 30.0%, p = 0.02). Primary cesarean, hypertensive disorders, postpartum hemorrhage, birthweight >90th percentile, macrosomia, and preterm birth frequencies were not significantly different between groups. Therefore, high-risk women diagnosed with GDM in early pregnancy were not more likely to have an adverse outcome compared to routinely diagnosed women. As they are a high-risk group, this may indicate a possible benefit to the early diagnosis of GDM.

澳大利亚妊娠糖尿病协会建议在妊娠24周之前筛查高危妇女妊娠糖尿病(GDM),假设早期诊断和有机会实现正常血糖将最大限度地减少不良后果。然而,几乎没有证据支持这一建议。研究目的是比较妊娠24周前诊断为GDM的高危妇女和妊娠24周后诊断为GDM的妇女的妊娠结局。根据国际糖尿病和妊娠研究小组的标准,对澳大利亚一家三级医院12个月内诊断为GDM的所有孕妇进行了回顾性审计。比较24周前诊断的“早期GDM”(n = 133)和24周后诊断的“晚期GDM”(n = 636)的不良围产期结局。与晚期GDM相比,早期GDM的新生儿复合结局频率(低血糖、出生创伤、NICU/SCN入院、死胎、新生儿死亡、呼吸窘迫和光疗)显著降低(20.3%比30.0%,p = 0.02)。原发性剖宫产、高血压疾病、产后出血、出生体重>90百分位、巨大儿和早产频率组间无显著差异。因此,在妊娠早期诊断为GDM的高危妇女与常规诊断的妇女相比,不太可能有不良后果。由于他们是高危人群,这可能对GDM的早期诊断有益。
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引用次数: 15
Quality of Prenatal Care and Associated Factors among Pregnant Women at Public Health Facilities of Wogera District, Northwest Ethiopia. 埃塞俄比亚西北部沃格拉区公共卫生机构孕妇产前护理质量及相关因素
IF 3.2 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2020-01-29 eCollection Date: 2020-01-01 DOI: 10.1155/2020/9592124
Asrat Kassaw, Ayal Debie, Demiss Mulatu Geberu

Background: Prenatal care refers to services a pregnant woman receives during pregnancy to ensure a healthy outcome for herself and her newborn. However, only limited studies have so far been done to assess the quality of prenatal care in the study area. Thus, this study is aimed at assessing the quality of prenatal care and associated factors at public health facilities in Wogera district, northwest Ethiopia.

Methods: An institution-based cross-sectional study was conducted in Wogera district from March to April 2019. A total of 465 pregnant women were interviewed using a semi-structured interviewer-administered questionnaire; consecutive sampling was used to select the participants. The binary logistic regression analysis model was fitted to identify the potential predictor variables. Variables with <0.2 p values were fitted into the multivariable logistic regression analysis model; <0.05 p values and an adjusted odds ratio (AOR) with a 95% confidence interval (CI) were used to declare factors associated with the quality of prenatal care.

Results: The overall quality of prenatal care was 32.7% (95% CI: 28.1, 37.2). Four or more prenatal care visits (AOR = 2.3; 95% CI: 1.2, 4.7), high maternal education (AOR = 2.9; 95% CI: 1.03, 7.93), over USD 175.5 monthly household income (AOR = 2.8; 95% CI: 1.1, 7.8), and the availability of maternity waiting areas (AOR = 2.4; 95% CI: 1.2, 5.0) were positively associated with the quality of the care.

Conclusion: The overall quality of prenatal care in this study was low. Therefore, promoting focused prenatal care and increasing infrastructure, encouraging maternal education, and compensating for the healthcare costs for women with low household income might enhance the quality of the care.

背景:产前护理是指孕妇在怀孕期间为确保自己和新生儿的健康结果而接受的服务。然而,到目前为止,只有有限的研究已经做了评估产前护理的质量在研究地区。因此,本研究旨在评估埃塞俄比亚西北部Wogera地区公共卫生设施的产前护理质量及其相关因素。方法:2019年3 - 4月在Wogera地区进行了一项基于机构的横断面研究。采用半结构化访谈问卷,共采访了465名孕妇;采用连续抽样的方法选择研究对象。拟合二元logistic回归分析模型以确定潜在的预测变量。将具有p值的变量拟合到多变量logistic回归分析模型中;使用p值和校正优势比(AOR)(95%置信区间(CI))来宣布与产前护理质量相关的因素。结果:产前护理总体质量为32.7% (95% CI: 28.1, 37.2)。4次及以上产前护理(AOR = 2.3;95% CI: 1.2, 4.7),高母亲教育程度(AOR = 2.9;95%置信区间:1.03,7.93),家庭月收入超过175.5美元(AOR = 2.8;95% CI: 1.1, 7.8),以及产妇候诊区的可用性(AOR = 2.4;95% CI: 1.2, 5.0)与护理质量呈正相关。结论:本研究的整体产前护理质量较低。因此,促进重点产前护理和增加基础设施、鼓励产妇教育和补偿家庭收入低的妇女的保健费用,可能会提高护理质量。
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引用次数: 27
Sociodemographic Factors Associated with Women's Perspectives on Male Involvement in Antenatal Care, Labour, and Childbirth. 与女性对男性参与产前护理、分娩和分娩的看法相关的社会人口因素。
IF 3.2 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2020-01-25 eCollection Date: 2020-01-01 DOI: 10.1155/2020/6421617
Shamsudeen Mohammed, Ibrahim Yakubu, Issahaku Awal

Background: Evidence suggests that in patriarchal societies such as Ghana, access to and survival of maternal and child healthcare services require the active involvement of men. However, interventions to promote men's involvement in maternal and child health care are less likely to succeed if the views and concerns of women are not considered. This study provides an understanding of women's perspective on men's involvement in antenatal care, labour, and childbirth in the Northern Region of Ghana.

Methods: Data for this cross-sectional study were collected from 300 pregnant women using a structured questionnaire. Logistic regression models were then used to determine the socio-demographic factors associated with women's perspectives on men's involvement in antenatal care, labour, and childbirth.

Results: The mean age of the participants was 28 (SD = 5.21) years. More than four-fifths of the women in this study express the desire for male partner involment in natenatal care (ANC) services (n = 258, 86%) and as companions during labour and child birth (n = 254, 84.7%). We found that married women were 9.8 times more likely (95%CI 1.59, 60.81) to encourage male involvement in ANC compared to women who were unmarried. The probability of encouraging male involvement in ANC decreased with increased level of education among the women while support for male companionship during childbirth increased significantly with an increased level of education. After accounting for the effect of other significant covariates, there was good evidence to suggest that married women (p = 0.002), women with only primary/Junior High School education (p = 0.048) and those with two (p = 0.010), three (p =  0.008), or ≥4 (p = 0.044) previous pregnancies had a desire for male partner involvement in ANC while women who attained secondary (p = 0.004) or tertiary (p = 0.001) level education expressed the desire for male companionship in labour and childbirth in the adjusted model.

Conclusion: Male involvement in antenatal care, labour, and childbirth received overwhelming support from the women in this study.

背景:证据表明,在加纳这样的父权制社会中,妇幼保健服务的获得和生存需要男子的积极参与。然而,如果不考虑妇女的意见和关切,促进男子参与妇幼保健的干预措施就不太可能成功。本研究提供了妇女对男子参与产前护理、劳动和分娩的看法的理解,在加纳北部地区。方法:采用结构化问卷对300名孕妇进行横断面研究。然后使用逻辑回归模型来确定与女性对男性参与产前护理、分娩和分娩的看法相关的社会人口因素。结果:参与者平均年龄28岁(SD = 5.21)岁。在这项研究中,超过五分之四的妇女表示希望男性伴侣参与产前保健(ANC)服务(n = 258, 86%),并在分娩和分娩期间作为伴侣(n = 254, 84.7%)。我们发现已婚女性鼓励男性参与ANC的可能性是未婚女性的9.8倍(95%CI 1.59, 60.81)。随着女性受教育程度的提高,鼓励男性参与ANC的可能性降低,而随着受教育程度的提高,支持男性陪伴分娩的可能性显著增加。在考虑了其他显著协变量的影响后,有充分的证据表明,已婚妇女(p = 0.002)、只受过小学/初中教育的妇女(p = 0.048)、受过两次教育的妇女(p = 0.010)、受过三次教育的妇女(p = 0.008)、或≥4次(p = 0.044)以前怀孕的女性希望男性伴侣参与ANC,而受过中等教育(p = 0.004)或高等教育(p = 0.001)的女性在调整后的模型中表达了在分娩和分娩时希望男性陪伴的愿望。结论:在本研究中,男性参与产前护理、分娩和分娩得到了女性压倒性的支持。
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引用次数: 8
期刊
Journal of Pregnancy
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