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Study of Lung Function in COVID-19 Pneumonia Recovered Individuals COVID-19肺炎恢复期患者肺功能的研究
Pub Date : 2023-01-31 DOI: 10.14260/jemds.v12i1.320
Mekala Kamala Priyadarshini, Moravineni Usha Rani
BACKGROUND Corona virus disease 2019 (COVID-19) is an acute respiratory infectious disease caused by severe acute respiratory syndrome corona virus 2 (SARS-CoV-2). Pulmonary system is the most commonly affected organ system by COVID-19. SARS-CoV-2 results in disruption of ACE/ACE2 balance leading to RAAS activation. The present study was carried out to determine the lung function in the recovery phase of COVID -19 by spirometry in India. METHODS A prospective (Follow up) observational study was done on 100 patients from March 2021 to November 2021. COVID-19 patients with RT-PCR positive results aged between 25 to 60 years were enrolled in the study. All the subjects were health care workers working in King George Hospital, Visakhapatnam. They were followed for a period of 3 months. RESULTS The mean age was 48.35 ± 11.07 years. 71 % were males. The mean height was 162.85 ± 7.47 cm while the mean weight was 36.71 ± 1.12 kg. During enrolment, the mean forced vital capacity (FVC) was 2.22 ± 0.68 L, forced expiratory volume (FEV1) was 1.97 ± 0.63 L and FEV1/FVC% was 89.35 ± 13.27 %. There was no statistically significant difference in FVC between enrolment and various periods of follow up at 1 and 3 months. There was a statistically significant difference between FEV1 and FEV1/FVC% between enrolment and various periods of follow up at 1 and 3 months. CONCLUSIONS COVID-19 infection has an impact on the lung functions. PFT done 3 months later after clinical cure/discharge showed an improvement in FEV1 and FEV1/FVC% in the present study. Long-term follow-up of the lung function in post-COVID-19 survivors is recommended.
背景2019冠状病毒病(COVID-19)是由严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)引起的急性呼吸道传染病。肺系统是最常受COVID-19影响的器官系统。SARS-CoV-2导致ACE/ACE2平衡中断,导致RAAS激活。本研究旨在通过肺活量测定法确定印度COVID -19恢复期的肺功能。方法于2021年3月至2021年11月对100例患者进行前瞻性(随访)观察性研究。该研究招募了年龄在25至60岁之间的RT-PCR阳性的COVID-19患者。所有研究对象都是在维沙卡帕特南乔治国王医院工作的卫生保健工作者。他们被跟踪了3个月。结果患者平均年龄48.35±11.07岁。71%是男性。平均身高162.85±7.47 cm,平均体重36.71±1.12 kg。入组时,平均用力肺活量(FVC)为2.22±0.68 L,用力呼气量(FEV1)为1.97±0.63 L, FEV1/FVC%为89.35±13.27%。入组后1个月和3个月随访期间FVC差异无统计学意义。FEV1和FEV1/FVC%在入组和1、3个月的不同随访期间有统计学差异。结论COVID-19感染对肺功能有影响。临床治愈/出院后3个月进行PFT显示FEV1和FEV1/FVC%在本研究中有所改善。建议对covid -19幸存者的肺功能进行长期随访。
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引用次数: 0
Foreign Body Impaction in the Buccal Mucosa of a Child – A Case Report 儿童口腔黏膜异物嵌塞1例报告
Pub Date : 2022-12-31 DOI: 10.14260/jemds.v11i13.293
Subalakshmi Krishnamurthy, Loganayagi Ramalingam, Karthikeyan Thirugnanasambandam
Foreign bodies may be traumatically or iatrogenically embedded in the oral cavity. Traumatic impaction of foreign bodies intraorally in children is common, as they are playful and are unaware of the consequences. A case of traumatic penetration of glass shards in the cheek of a 10-year-old female child which is present for three years, and its management is discussed here and the importance of detailed case history, clinical and radiographic examinations in arriving at the diagnosis and planning the treatment are presented in this article. Foreign bodies are objects that are not native to the human body, and they may be ingested, inserted into a body cavity, or deposited into the body by traumatic or iatrogenic injury.[1] Traumatic foreign body impaction in oral cavity is mostly due to assaults and motor vehicle accidents[2] or sometimes may be due to blast injury. Foreign bodies generally in oral cavity may be broken instruments, restorative materials, needles etc., or may range from fish bones, coins, stapler pins, small toys, metal pieces which may be quite common in younger age groups.[3] The foreign bodies once impacted get localized and ensue fibrosis and host response depending on the type of the material impacted. They may cause swelling, abscess formation, septicaemia, or lead to severe haemorrhage; may also undergo distant embolization.[1] Here we report a case of traumatic penetration of glass shards into the buccal mucosa of a female child due to a blast injury which was there for three years without any major complaints.
异物可能因创伤或医源性原因嵌入口腔。儿童口腔内异物的创伤性嵌塞很常见,因为他们很顽皮,没有意识到后果。本文讨论了一例10岁女性儿童脸颊玻璃碎片创伤性穿透的病例及其处理,并介绍了详细的病史、临床和放射学检查在诊断和计划治疗中的重要性。异物是非人体固有的物体,它们可能被摄入、插入体腔或因创伤或医源性损伤而沉积在体内。[1] 外伤性口腔异物嵌塞主要是由于袭击和机动车事故[2],有时可能是由于爆炸伤。口腔中的异物通常可能是破损的器械、修复材料、针头等,也可能是鱼骨、硬币、订书针、小玩具、金属片等,这些在年轻群体中很常见。[3] 异物一旦受到影响就会被定位,并根据受影响材料的类型产生纤维化和宿主反应。它们可能导致肿胀、脓肿形成、败血症或导致严重出血;也可以进行远距离栓塞。[1] 在这里,我们报告了一例因爆炸伤导致玻璃碎片创伤性穿透一名女性儿童口腔粘膜的病例,该病例持续了三年,没有任何重大投诉。
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引用次数: 0
Iridocorneal Endothelial Syndrome – A Case Report 虹膜内皮综合征一例报告
Pub Date : 2022-12-31 DOI: 10.14260/jemds.v11i13.294
Manohar Sungar, Mallikarjun Heralgi, Roopasree Bhadrappanavar Vishwamurthy
Iridocorneal endothelial (ICE) syndrome is a rare ophthalmic disorder, wherein the basic pathology is an abnormal corneal endothelium that leads to varying degrees of corneal oedema, iris atrophy, and secondary angle closure glaucoma.[1] This syndrome typically affects young women unilaterally with no family history.[2] The true aetiology of ICE syndrome is unclear. Viral cause for the disease has been proposed, based on a history of inflammation in certain cases and on the presence of inflammatory cells on histological analysis.[3] The abnormal endothelial cells may migrate posteriorly, forming a membrane that covers the adjacent structures, iris and trabecular meshwork.[4] The contraction of this membrane leads to characteristic iris changes, iridotrabecular synechiae, and corectopia with the pupil being drawn towards the area where the synechiae are most prevalent and to secondary angle-closure glaucoma.[5]
虹膜内皮综合征是一种罕见的眼科疾病,其基本病理是角膜内皮异常,导致不同程度的角膜水肿、虹膜萎缩和继发性闭角型青光眼。[1] 这种综合征通常只影响没有家族史的年轻女性。[2] ICE综合征的真正病因尚不清楚。根据某些病例的炎症史和组织学分析中炎症细胞的存在,提出了该疾病的病毒病因。[3] 异常内皮细胞可能向后迁移,形成覆盖相邻结构、虹膜和小梁网的膜。[4] 该膜的收缩导致虹膜的特征性变化、虹膜三眼粘连和共视,瞳孔被拉向粘连最普遍的区域,并导致继发性闭角型青光眼。[5]
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引用次数: 0
Impact of Covid-19 Pandemic on Mental Wellbeing of Healthcare Professionals: A Cross-Sectional Study 新冠肺炎大流行对医护人员心理健康的影响:一项跨部门研究
Pub Date : 2022-12-31 DOI: 10.14260/jemds.v11i13.290
Meesala Rama Devi, Moravineni Usha Rani
BACKGROUND COVID 19 pandemic posed a varied group of challenges to health care workers (HCWs) like new disease with no treatment, less treatment options available, worry for infection to family members, shortage of personal protective equipment (PPEs), uncertainty, and stress associated with lockdowns. HCWs are highly vulnerable to negative mental distress; this psychological distress varies in different group of HCWs and also on different psychological domains. In this study, we wanted to assess the impact of COVID 19 on the psychological well-being of health care professionals when providing care to COVID-19 patients. METHODS A cross-sectional observational study was conducted on doctors providing care to COVID -19 patients at King George Hospital, Visakhapatnam, during the second wave of COVID from March 2021 to December 2021. The questionnaire included three domains – Personal questions, work related questions, and pandemic related questions. The response to the questions was recorded in Likert’s scale. RESULTS 50 (50.00 %) were sometimes physically exhausted, 49 (49.00 %) participants were sometimes emotionally exhausted, and 46 (46.00 %) participants reported that sometimes they felt worn out (extremely tired). 54 (54.00 %) participants reported that sometimes they were frustrated with their work, and 46 (46.00 %) participants reported sometimes feeling burnt out because of the work. 48 (48.00 %) participants reported sometimes feeling depressed, 38 (38.00 %) participants stated sometime having a fear of catching COVID-19 infection, and 44 (44.00 %) participants reported consistently having to fear of family members getting infected due to the exposure in work environment. CONCLUSIONS In total, COVID-19 had a negative effect on psychological well-being of the HCWs, but that was not severe to cause any specific psychological disorders. There was no significant difference in mental health impact between the genders and age groups of the participants.
背景2019冠状病毒病大流行给医护人员带来了各种各样的挑战,如没有治疗的新疾病、可用的治疗选择较少、担心家人感染、个人防护设备短缺、不确定性以及与封锁相关的压力。HCW极易受到负面心理困扰;这种心理困扰在不同的HCW群体中以及在不同的心理领域中都有所不同。在这项研究中,我们希望评估COVID 19在为新冠肺炎患者提供护理时对卫生保健专业人员心理健康的影响。方法对2021年3月至2021年12月第二波COVID期间维萨卡帕特南乔治国王医院为COVID-19患者提供护理的医生进行横断面观察性研究。问卷包括三个领域——个人问题、工作相关问题和疫情相关问题。对这些问题的回答被记录在Likert的量表中。结果50名(50.00%)参与者有时身体疲惫,49名(49.00%)参与者有时情绪疲惫,46名(46.00%)参与者报告有时感到疲惫(极度疲劳)。54名(54.00%)参与者表示,有时他们对自己的工作感到沮丧,46名(46.00%)参与者报告称,有时会因为工作而感到精疲力竭。48名(48.00%)参与者报告有时感到抑郁,38名(38.00%)参与者表示有时担心感染新冠肺炎,44名(44.00%)参与者一直担心家人因暴露在工作环境中而感染。结论总体而言,新冠肺炎对HCW的心理健康有负面影响,但并不严重,不会导致任何特定的心理障碍。参与者的性别和年龄组在心理健康影响方面没有显著差异。
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引用次数: 0
Changing Patterns in the Distribution of Skin Lesions of Scabies during the COVID -19 Pandemic – A Cross-Sectional Observational Study COVID -19大流行期间疥疮皮损分布的变化模式——一项横断面观察研究
Pub Date : 2022-12-31 DOI: 10.14260/jemds.v11i13.289
Chanchal Chauhan, Praveen Kumar Rathore, Aarzoo Pahwa
BACKGROUND An ectoparasitic disease, scabies, caused by the mite Sarcoptes scabiei var hominis. Some of the predisposing factors are overcrowding, unhygienic surroundings, immunocompromised status, dementia, homelessness, and sexual contact. In this study, we wanted to evaluate the changed distribution of lesions of scabies during pandemic. METHODS A cross sectional study was performed on 600 patients attending the skin department of our tertiary care hospital over a period of 6 months. The sites of the scabies lesions were noted along with types of lesions. Demographic data and history of regular hand washing and sanitization were also documented. RESULTS Our study revealed an important correlation between change in pattern of distribution of scabies lesions from being less frequent on finger webs (19 %) to being more frequent on abdomen (periumbilical area) (73 %) and groins (67 %) due to regular hand washing and frequent sanitization, in this pandemic era. CONCLUSIONS A significant change in distribution of skin lesions in scabies can be noticed during this COVID-19 pandemic.
背景:疥疮是一种由疥螨引起的体外寄生虫病。一些诱发因素包括过度拥挤、不卫生的环境、免疫功能低下、痴呆、无家可归和性接触。在这项研究中,我们想评估大流行期间疥疮病变分布的变化。方法对在我院三级医院皮肤科就诊的600例患者进行为期6个月的横断面研究。疥疮病变的部位与病变类型一起被记录下来。还记录了人口统计数据和定期洗手和卫生处理的历史。结果我们的研究显示,在这个大流行时代,由于经常洗手和经常消毒,疥疮病变分布模式的变化与手指蹼(19%)较少发生到腹部(脐周)(73%)和腹股沟(67%)较多发生之间存在重要的相关性。结论本次新冠肺炎大流行期间,疥疮皮损分布发生显著变化。
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引用次数: 0
A Comparison of Air-Q and I-Gel in Terms of Insertion Conditions and as Intubating Aids for Elective Surgeries under General Anaesthesia Air-Q与I-Gel在全麻下择期手术中插入条件及辅助插管的比较
Pub Date : 2022-12-31 DOI: 10.14260/jemds.v11i13.291
Babita Ramdev, Heena Goyal, Dinesh Kumar Sharma, Archit Sharma
BACKGROUND Supraglottic airway devices (SAD) like air Q and I-Gel are widely used in place of tracheal intubation for general anaesthesia. The present study was undertaken to compare the insertion conditions of these two supraglottic airway devices and as conduits for endotracheal tube (ETT) insertion in adult patients undergoing elective surgeries. METHODS 100 patients belonging to American Society of Anaesthesiologists (ASA) grade 1 and 2 between 18 to 70 years were randomly divided into 2 groups of 50 each. In group A, Air-Q was used and in group B, I-gel. The following parameters were compared while inserting SAD and endotracheal tube (ETT): number of insertion attempts, insertion time, ease of insertion, intraoperative and postoperative complications. RESULTS Insertion in first attempt was 90 % in air- Q and 72 % in I-gel. The mean time of insertion for air-Q was 7.28  1.46 seconds which  was shorter as compared to I-gel which was 8.46  2.18 seconds (p = 0.002). Air Q was easy to insert in 93 % cases and I-Gel in 52 % cases. ETT insertion through Air-Q was easy when compared to I-Gel .Complications occurred in some patients in both the groups. CONCLUSIONS We concluded that Air-Q has better efficacy than I-gel in terms of insertion conditions and as a conduit for endotracheal intubation.
背景声门上气道装置(SAD)如air Q和I-Gel被广泛用于代替气管插管进行全身麻醉。本研究的目的是比较这两种声门上气道装置的插入条件,以及作为气管内插管(ETT)导管在接受选择性手术的成人患者中的插入情况。方法选取年龄在18 ~ 70岁的美国麻醉医师学会(ASA) 1级和2级患者100例,随机分为2组,每组50例。A组采用Air-Q, B组采用I-gel。比较气管插管(ETT)与气管插管(SAD)的插管次数、插管时间、插管难易程度、术中及术后并发症。结果空气- Q和I-gel的首次插入率分别为90%和72%。air-Q的平均插入时间为7.28 1.46秒,比I-gel的8.46 2.18秒短(p = 0.002)。Air Q易于插入的占93%,I-Gel易于插入的占52%。与I-Gel插管相比,Air-Q插管容易,但两组均有部分患者出现并发症。结论Air-Q作为气管插管导管的置入条件优于I-gel。
{"title":"A Comparison of Air-Q and I-Gel in Terms of Insertion Conditions and as Intubating Aids for Elective Surgeries under General Anaesthesia","authors":"Babita Ramdev, Heena Goyal, Dinesh Kumar Sharma, Archit Sharma","doi":"10.14260/jemds.v11i13.291","DOIUrl":"https://doi.org/10.14260/jemds.v11i13.291","url":null,"abstract":"BACKGROUND \u0000Supraglottic airway devices (SAD) like air Q and I-Gel are widely used in place of tracheal intubation for general anaesthesia. The present study was undertaken to compare the insertion conditions of these two supraglottic airway devices and as conduits for endotracheal tube (ETT) insertion in adult patients undergoing elective surgeries. \u0000METHODS \u0000100 patients belonging to American Society of Anaesthesiologists (ASA) grade 1 and 2 between 18 to 70 years were randomly divided into 2 groups of 50 each. In group A, Air-Q was used and in group B, I-gel. The following parameters were compared while inserting SAD and endotracheal tube (ETT): number of insertion attempts, insertion time, ease of insertion, intraoperative and postoperative complications. \u0000RESULTS \u0000Insertion in first attempt was 90 % in air- Q and 72 % in I-gel. The mean time of insertion for air-Q was 7.28  1.46 seconds which  was shorter as compared to I-gel which was 8.46  2.18 seconds (p = 0.002). Air Q was easy to insert in 93 % cases and I-Gel in 52 % cases. ETT insertion through Air-Q was easy when compared to I-Gel .Complications occurred in some patients in both the groups. \u0000CONCLUSIONS \u0000We concluded that Air-Q has better efficacy than I-gel in terms of insertion conditions and as a conduit for endotracheal intubation.","PeriodicalId":47072,"journal":{"name":"Journal of Evolution of Medical and Dental Sciences-JEMDS","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45993001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extensive Epipericardial Fat Necrosis in a Case of Metastatic Adenocarcinoma of Lung 肺转移性腺癌广泛的心包外脂肪坏死1例
Pub Date : 2022-12-31 DOI: 10.14260/jemds.v11i13.295
Sujata Singh, Superna Ganguly
Epipericardial fat necrosis is an uncommon benign and self-limiting condition that leads patients to the emergency department owing to the onset of acute pleuritic chest pain. Fat necrosis in adipose tissue can occur at various sites: in the breast and subcutaneous fat after trauma, peripancreatic fat in pancreatitis, and epiploicappendagitis.[1,2] Rarely, it may occur within the epipericardial fat. Since the first description by Jackson et al.,[3] only 35 cases have been published in the English literature, and extensive epipericardial fat necrosis (EFN) is currently described as an extremely rare disease.[4] The aetiology of EFN remains unknown, but some theories have been proposed to explain its origin. Acute torsion of a vascular pedicle is described in some cases, although the presence of a vascular pedicle has been described in only two patients who underwent surgery.[4] Furthermore, increased intrathoracic pressure due to heavy lifting or Valsalva's manoeuvre might trigger rapid changes in capillary pressure, leading to haemorrhagic necrosis, especially if pre-existing structural abnormalities of the adipose tissue, such as lipoma, hamartoma or lipomatosis, are present.[5] Both males and females are affected, and neither age predilections nor pre-disposing factors have been described.[4]
心包外脂肪坏死是一种罕见的良性自限性疾病,由于急性胸膜炎性胸痛的发作,患者会去急诊室。脂肪组织中的脂肪坏死可以发生在不同的部位:创伤后的乳房和皮下脂肪,胰腺炎时的胰周脂肪,以及网膜下炎。[1,2]很少发生在心外膜脂肪内。自Jackson等人首次描述以来,[3]在英国文献中仅发表了35例病例,广泛的心外膜脂肪坏死(EFN)目前被描述为一种极为罕见的疾病。[4] EFN的病因仍然未知,但已经提出了一些理论来解释其起源。血管蒂的急性扭转在某些情况下被描述,尽管只有两名接受手术的患者描述了血管蒂的存在。[4] 此外,由于举重或瓦尔萨尔瓦手法导致的胸腔内压力增加可能会引发毛细血管压力的快速变化,导致出血性坏死,特别是如果存在脂肪组织的预先存在的结构异常,如脂肪瘤、错构瘤或脂肪增多症。[5] 男性和女性都受到影响,既没有年龄偏好,也没有预处理因素的描述。[4]
{"title":"Extensive Epipericardial Fat Necrosis in a Case of Metastatic Adenocarcinoma of Lung","authors":"Sujata Singh, Superna Ganguly","doi":"10.14260/jemds.v11i13.295","DOIUrl":"https://doi.org/10.14260/jemds.v11i13.295","url":null,"abstract":"Epipericardial fat necrosis is an uncommon benign and self-limiting condition that leads patients to the emergency department owing to the onset of acute pleuritic chest pain. Fat necrosis in adipose tissue can occur at various sites: in the breast and subcutaneous fat after trauma, peripancreatic fat in pancreatitis, and epiploicappendagitis.[1,2] Rarely, it may occur within the epipericardial fat. Since the first description by Jackson et al.,[3] only 35 cases have been published in the English literature, and extensive epipericardial fat necrosis (EFN) is currently described as an extremely rare disease.[4] The aetiology of EFN remains unknown, but some theories have been proposed to explain its origin. Acute torsion of a vascular pedicle is described in some cases, although the presence of a vascular pedicle has been described in only two patients who underwent surgery.[4] Furthermore, increased intrathoracic pressure due to heavy lifting or Valsalva's manoeuvre might trigger rapid changes in capillary pressure, leading to haemorrhagic necrosis, especially if pre-existing structural abnormalities of the adipose tissue, such as lipoma, hamartoma or lipomatosis, are present.[5] Both males and females are affected, and neither age predilections nor pre-disposing factors have been described.[4]","PeriodicalId":47072,"journal":{"name":"Journal of Evolution of Medical and Dental Sciences-JEMDS","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44836014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Testicular Leiomyoma: Report of a Rare Case 睾丸平滑肌瘤1例报告
Pub Date : 2022-12-31 DOI: 10.14260/jemds.v11i13.292
Sujata Singh, Sarika More
Leiomyomas are benign tumours that can arise from any organ containing smooth muscle cells. They are commonly seen in the uterus but can also be found in other sites like the renal pelvis, bladder, spermatic cord, epididymis, prostate, scrotum and glans penis. Testis-associated leiomyomas are extremely rare. We present a case of testicular leiomyoma in a 69-year-old male who presented with a slowly growing, painless, firm, mobile lump in the left side of the scrotum. Histopathology and Immunohistochemistry showed findings suggestive of Leiomyoma.
平滑肌瘤是一种良性肿瘤,可起源于任何含有平滑肌细胞的器官。它们常见于子宫,但也见于其他部位,如肾盂、膀胱、精索、附睾、前列腺、阴囊和阴茎头。睾丸相关的平滑肌瘤极为罕见。我们报告一个69岁男性睾丸平滑肌瘤的病例,他在阴囊左侧出现一个缓慢生长,无痛,坚固,可移动的肿块。组织病理及免疫组化显示为平滑肌瘤。
{"title":"Testicular Leiomyoma: Report of a Rare Case","authors":"Sujata Singh, Sarika More","doi":"10.14260/jemds.v11i13.292","DOIUrl":"https://doi.org/10.14260/jemds.v11i13.292","url":null,"abstract":"Leiomyomas are benign tumours that can arise from any organ containing smooth muscle cells. They are commonly seen in the uterus but can also be found in other sites like the renal pelvis, bladder, spermatic cord, epididymis, prostate, scrotum and glans penis. Testis-associated leiomyomas are extremely rare. We present a case of testicular leiomyoma in a 69-year-old male who presented with a slowly growing, painless, firm, mobile lump in the left side of the scrotum. Histopathology and Immunohistochemistry showed findings suggestive of Leiomyoma.","PeriodicalId":47072,"journal":{"name":"Journal of Evolution of Medical and Dental Sciences-JEMDS","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44618395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Six Months Follow-Up Study on Health Care Workers on Persistence of Antibodies to SARS-CoV-2 after Covishield Vaccination 医护人员接种covshield后SARS-CoV-2抗体持续半年随访研究
Pub Date : 2022-11-30 DOI: 10.14260/jemds.v11i12.263
Shinjini Chaudhuri, Shivaraj Afzalpurkar, Vikram Uttam Patil, Gajanan Ashok Rodge, Mohuya Mukherjee, Surabhi Jajodia, Usha Goenka, Mahesh Kumar Goenka
BACKGROUND Efficacy of COVID vaccines has been evaluated in various studies. The interim analysis from four randomized controlled trials in UK, Brazil, and south Africa regarding efficacy of two doses of the vaccine was found to be 70.4% (95·8% CI 54·8–80·6). There is a limited data on follow-up Ab titer post vaccination. Hence, the current study is first of its kind with the objective to determine vaccine long term efficacy and its determinants. METHODS Health Care Workers (HCW) from Apollo Multispeciality Hospitals, Kolkata who underwent Covishield vaccination from January 2021 to April 2021 were included in the study. Serological testing was done prior to first and second dose of vaccinations, and additionally around six months post second dose. RESULTS Between January 2021 to April 2021, 2032 HCW, with predominant age of less than 30 years (44.83%) and male gender (61.96%) undergoing Covishield vaccination were enrolled. Antibodies were detected in 953 (46.9%) individuals prior to first dose, 1449 out of 1495 (96.9%) remained positive prior to second dose and 465 out of 504 (92.3%) HCW after 6 months and remaining 39 (7.7%) either had lost or never had antibodies in their blood. The mean ± SD value of first, second and third antibodies were 2.35 ± 3.10, 10.46 ± 4.84 and 8.75 ± 4.88 respectively. CONCLUSIONS This study provides long observation period, covering the complete progress of the pandemic which provides a “real-life” picture of the antibody level dynamics over time, and after vaccination.
背景新冠肺炎疫苗的有效性已经在各种研究中进行了评估。在英国、巴西和南非进行的四项随机对照试验中,关于两剂疫苗有效性的中期分析结果为70.4%(95.8%CI 54.8-80.6)。关于疫苗接种后Ab滴度的随访数据有限。因此,目前的研究是同类研究中的第一项,目的是确定疫苗的长期疗效及其决定因素。方法将加尔各答阿波罗多专科医院的医护人员(HCW)纳入研究,他们在2021年1月至2021年4月期间接受了Covishield疫苗接种。血清学检测在第一剂和第二剂疫苗接种前进行,另外在第二剂接种后约六个月进行。结果在2021年1月至2021年4月期间,2032名主要年龄小于30岁(44.83%)、男性(61.96%)接受Covishield疫苗接种的HCW入选。在第一次给药前,953人(46.9%)检测到抗体,1495人中有1449人(96.9%)在第二次给药后仍呈阳性,504人中有465人(92.3%)在6个月后HCW,其余39人(7.7%)血液中抗体丢失或从未有过抗体。第一抗体、第二抗体和第三抗体的平均±SD值分别为2.35±3.10、10.46±4.84和8.75±4.88。结论这项研究提供了很长的观察期,涵盖了大流行的完整进展,提供了抗体水平随时间和疫苗接种后动态的“真实”画面。
{"title":"Six Months Follow-Up Study on Health Care Workers on Persistence of Antibodies to SARS-CoV-2 after Covishield Vaccination","authors":"Shinjini Chaudhuri, Shivaraj Afzalpurkar, Vikram Uttam Patil, Gajanan Ashok Rodge, Mohuya Mukherjee, Surabhi Jajodia, Usha Goenka, Mahesh Kumar Goenka","doi":"10.14260/jemds.v11i12.263","DOIUrl":"https://doi.org/10.14260/jemds.v11i12.263","url":null,"abstract":"BACKGROUND \u0000Efficacy of COVID vaccines has been evaluated in various studies. The interim analysis from four randomized controlled trials in UK, Brazil, and south Africa regarding efficacy of two doses of the vaccine was found to be 70.4% (95·8% CI 54·8–80·6). There is a limited data on follow-up Ab titer post vaccination. Hence, the current study is first of its kind with the objective to determine vaccine long term efficacy and its determinants. \u0000METHODS \u0000Health Care Workers (HCW) from Apollo Multispeciality Hospitals, Kolkata who underwent Covishield vaccination from January 2021 to April 2021 were included in the study. Serological testing was done prior to first and second dose of vaccinations, and additionally around six months post second dose. \u0000RESULTS \u0000Between January 2021 to April 2021, 2032 HCW, with predominant age of less than 30 years (44.83%) and male gender (61.96%) undergoing Covishield vaccination were enrolled. Antibodies were detected in 953 (46.9%) individuals prior to first dose, 1449 out of 1495 (96.9%) remained positive prior to second dose and 465 out of 504 (92.3%) HCW after 6 months and remaining 39 (7.7%) either had lost or never had antibodies in their blood. The mean ± SD value of first, second and third antibodies were 2.35 ± 3.10, 10.46 ± 4.84 and 8.75 ± 4.88 respectively. \u0000CONCLUSIONS \u0000This study provides long observation period, covering the complete progress of the pandemic which provides a “real-life” picture of the antibody level dynamics over time, and after vaccination.","PeriodicalId":47072,"journal":{"name":"Journal of Evolution of Medical and Dental Sciences-JEMDS","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42817244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unmet Needs for Healthcare Services among People in the Field Practice Area of A Rural Health and Training Centre in Goa - A Descriptive Cross-Sectional Study 果阿邦农村卫生和培训中心现场实践区人们对卫生保健服务的未满足需求——一项描述性横断面研究
Pub Date : 2022-11-30 DOI: 10.14260/jemds.v11i12.264
Manisha Kankonker, Prajoth Kankonkar, Amit Dias, Rajat Sawant
BACKGROUND Universal Health Coverage (UHC) means that individuals and communities receive the healthcare services they need without suffering financial hardship. It includes the full spectrum of essential, quality healthcare services, from health promotion to prevention, treatment, rehabilitation and palliative care. Unmet Healthcare Needs (UHNs) are defined as the difference between the healthcare services deemed necessary to deal with a particular health problem and the actual services received. UHC is possible only if we identify the UHNs among people and plan the delivery of healthcare services accordingly. The study aimed to identify the UHNs among the people in the field practice area of a Rural Health and Training Centre (RHTC), Mandur in Goa.  METHODS A community-based cross-sectional study was conducted in a rural area. A multistage sampling technique was used to include 160 study participants of 21 years of age or above. A semi-structured questionnaire was used to collect data which was later entered into Google Sheets and analysed using SPSS.  RESULTS The mean age of study participants was 44 years (95% CI 41-47). The majority were males (53.13%), 65% were Hindus, and most of them (38.75%) had completed secondary school education, however, more than half (53.13%) of them were unemployed. Twenty-six percent of the study participants reported UHNs during their last visit to a healthcare facility.  CONCLUSIONS The majority of the UHNs consisted of radiological investigations such as X-Ray and Ultrasound. Similarly, the most commonly perceived UHNs was also for radiological investigations followed by the unavailability of general practitioner, medicines and dentist.
全民健康覆盖意味着个人和社区在不遭受经济困难的情况下获得所需的卫生保健服务。它包括从促进健康到预防、治疗、康复和姑息治疗的所有基本优质保健服务。未满足的医疗保健需求(UHNs)的定义是处理特定健康问题所需的医疗保健服务与实际获得的服务之间的差距。只有当我们确定人群中的全民健康覆盖者并相应地规划提供卫生保健服务时,才有可能实现全民健康覆盖。该研究的目的是确定果阿邦曼都尔农村卫生和培训中心(RHTC)实地实践领域人员中的unhn。方法在农村地区进行以社区为基础的横断面研究。采用多阶段抽样技术对160名年龄在21岁及以上的研究参与者进行了抽样。采用半结构化问卷收集数据,随后输入谷歌Sheets并使用SPSS进行分析。研究参与者的平均年龄为44岁(95% CI 41-47)。大多数是男性(53.13%),65%是印度教徒,其中大多数(38.75%)完成了中学教育,然而,超过一半(53.13%)的人失业。26%的研究参与者在他们最后一次去医疗机构时报告了uhn。结论:绝大多数UHNs由x线和超声等放射学检查组成。同样,最普遍认为的不健康状况也是用于放射检查,其次是没有全科医生、药品和牙医。
{"title":"Unmet Needs for Healthcare Services among People in the Field Practice Area of A Rural Health and Training Centre in Goa - A Descriptive Cross-Sectional Study","authors":"Manisha Kankonker, Prajoth Kankonkar, Amit Dias, Rajat Sawant","doi":"10.14260/jemds.v11i12.264","DOIUrl":"https://doi.org/10.14260/jemds.v11i12.264","url":null,"abstract":"BACKGROUND \u0000Universal Health Coverage (UHC) means that individuals and communities receive the healthcare services they need without suffering financial hardship. It includes the full spectrum of essential, quality healthcare services, from health promotion to prevention, treatment, rehabilitation and palliative care. Unmet Healthcare Needs (UHNs) are defined as the difference between the healthcare services deemed necessary to deal with a particular health problem and the actual services received. UHC is possible only if we identify the UHNs among people and plan the delivery of healthcare services accordingly. The study aimed to identify the UHNs among the people in the field practice area of a Rural Health and Training Centre (RHTC), Mandur in Goa. \u0000 METHODS \u0000A community-based cross-sectional study was conducted in a rural area. A multistage sampling technique was used to include 160 study participants of 21 years of age or above. A semi-structured questionnaire was used to collect data which was later entered into Google Sheets and analysed using SPSS. \u0000 RESULTS \u0000The mean age of study participants was 44 years (95% CI 41-47). The majority were males (53.13%), 65% were Hindus, and most of them (38.75%) had completed secondary school education, however, more than half (53.13%) of them were unemployed. Twenty-six percent of the study participants reported UHNs during their last visit to a healthcare facility. \u0000 CONCLUSIONS \u0000The majority of the UHNs consisted of radiological investigations such as X-Ray and Ultrasound. Similarly, the most commonly perceived UHNs was also for radiological investigations followed by the unavailability of general practitioner, medicines and dentist.","PeriodicalId":47072,"journal":{"name":"Journal of Evolution of Medical and Dental Sciences-JEMDS","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41900231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Journal of Evolution of Medical and Dental Sciences-JEMDS
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