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High-Tensile Strength Suture Materials in Orthopaedics. 骨科中的高强度缝合材料。
IF 2.4 Q2 SURGERY Pub Date : 2025-03-25 eCollection Date: 2025-03-01 DOI: 10.2106/JBJS.RVW.24.00193
Naga Suresh Cheppalli, Sreenivasulu Metikala, Prabhudev Prasad Purudappa, Geneva Tranchida, Daniel C Washer

» High-tensile strength suture materials (HTSSMs) have significantly advanced the field of orthopaedic surgery by providing superior strength, enhanced handling characteristics, and improved durability compared with first-generation sutures.» These sutures are critical for ensuring repair integrity during the healing process of tendon-to-bone or tendon-to-tendon constructs.» While second-generation HTSSMs such as FiberWire, Orthocord, and Force Fiber offer higher tensile strength, better knot security, and reduced creep, their mechanical and biological properties vary, making it essential for surgeons to tailor their choice based on the tissue type, surgical technique, and patient-specific factors.» The incorporation of advanced materials such as ultra-high molecular weight polyethylene and innovative designs such as core-plus-braid configurations has further minimized risks of failure from abrasion, knot slippage, or tissue cut through.» Despite these advancements, challenges such as potential tissue irritation, granuloma formation, and suture cutout remain. Selecting the appropriate HTSSM involves balancing mechanical strength with handling properties and biological responses.» Flat sutures distribute load more evenly and are less prone to tissue cutout, making them ideal for delicate tissues, while round sutures offer better abrasion resistance in high-stress repairs.» In addition, understanding key properties such as stiffness, creep, and knot security can help optimize outcomes and minimize complications.» Surgeons should remain vigilant about the trade-offs associated with material coatings and knot volume, as these factors can influence both repair success and postoperative tissue health.

"与第一代缝合线相比,高拉伸强度缝合材料(HTSSM)具有更高的强度、更强的操作特性和更佳的耐用性,从而极大地推动了矫形外科领域的发展"。这些缝合线对于确保肌腱对骨或肌腱对肌腱构造愈合过程中的修复完整性至关重要"。虽然 FiberWire、Orthocord 和 Force Fiber 等第二代 HTSSM 具有更高的拉伸强度、更好的打结安全性和更低的蠕变性,但它们的机械和生物特性各不相同,因此外科医生必须根据组织类型、手术技术和患者的具体因素进行选择。先进材料(如超高分子量聚乙烯)和创新设计(如核心加编织带配置)的采用进一步降低了因磨损、绳结滑动或组织切穿而导致失败的风险。尽管取得了这些进步,但潜在的组织刺激、肉芽肿形成和缝线切断等挑战依然存在。选择合适的 HTSSM 需要在机械强度、处理特性和生物反应之间取得平衡"。扁平缝合线能更均匀地分配负荷,不易出现组织切口,因此非常适合娇嫩组织,而圆形缝合线在高应力修复中具有更好的耐磨性。此外,了解硬度、蠕变和打结安全性等关键特性有助于优化治疗效果和减少并发症"。外科医生应该对与材料涂层和线结数量相关的权衡保持警惕,因为这些因素会影响修复的成功率和术后组织的健康。
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引用次数: 0
Team Approach: An Interdisciplinary Framework for Weight Loss Before Total Joint Arthroplasty Surgery. 团队方法:全关节成形术前减肥的跨学科框架。
IF 2.4 Q2 SURGERY Pub Date : 2025-03-25 eCollection Date: 2025-03-01 DOI: 10.2106/JBJS.RVW.24.00002
Tiffany Lee, Nihar Pathare, Shawn Okpara, Abdullah Ghali, Melvyn A Harrington, Joseph R Young

» Obesity is a public health concern, with 41.9% of the US population classified as obese. Obesity increases the risk of chronic disease, type II diabetes, cardiovascular diseases, etc., leading to increased morbidity and mortality. Obesity has been identified as an independent risk factor of postoperative complications, including infection and impaired wound healing, following elective surgery. In total joint arthroplasty, it has been well elucidated that obese patients are predisposed to higher rates of postoperative complications, longer hospital stays, and increased cost of stay.» Obesity is influenced by the interplay between many societal, behavioral, and socioeconomic factors and requires a multidisciplinary approach to treatment. The patient's care team should be well versed in nutritional counseling, behavioral health counseling, medication management, and surgery to allow for a comprehensive approach.» Orthopaedic surgeons, dietitians, nutritionists, weight-loss physicians, and bariatric surgeons all play a critical role in treating this patient population. This review highlights the roles of these practitioners in developing an interdisciplinary framework to help patients with hip and knee arthritis lose weight before joint replacement surgery. Not only will this afford more patients the quality-of-life benefits that come with a hip or knee replacement but will also serve to decrease the complication rates associated with this patient cohort.» The aim of this review was to educate orthopaedic surgeons on various strategies that can be used to best optimize these patients for successful joint replacement surgery.

"肥胖是一个公共健康问题,美国有 41.9% 的人口被归类为肥胖。肥胖会增加罹患慢性疾病、II 型糖尿病、心血管疾病等的风险,导致发病率和死亡率上升。肥胖已被确定为选择性手术后出现术后并发症(包括感染和伤口愈合受损)的独立风险因素。在全关节置换术中,肥胖患者术后并发症发生率较高,住院时间较长,住院费用增加,这一点已得到充分阐明"。肥胖受许多社会、行为和社会经济因素的影响,需要多学科的治疗方法。患者的护理团队应精通营养咨询、行为健康咨询、药物管理和手术,以便采取综合方法"。"矫形外科医生、营养师、营养学家、减重内科医生和减肥外科医生在治疗这类患者的过程中都发挥着至关重要的作用。本综述强调了这些医生在制定跨学科框架以帮助髋关节和膝关节炎患者在关节置换手术前减轻体重方面的作用。这不仅能让更多患者享受到髋关节或膝关节置换术带来的生活质量益处,还能降低这类患者的并发症发生率"。这篇综述的目的是向骨科外科医生传授各种策略,以最佳方式帮助这些患者成功完成关节置换手术。
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引用次数: 0
Intertrochanteric Fractures in the Elderly Treated with Different Intramedullary Devices: A Systematic Review and Meta-Analysis Based on Comparison Studies. 不同髓内装置治疗老年股骨粗隆间骨折:基于比较研究的系统回顾和荟萃分析。
IF 2.4 Q2 SURGERY Pub Date : 2025-03-25 eCollection Date: 2025-03-01 DOI: 10.2106/JBJS.RVW.24.00203
Noah David Miller, Thomas Cho, Laya Gokula, Jiayong Liu

Background: Intertrochanteric fractures in the elderly present significant management challenges, with intramedullary (IM) nails increasingly used for fixation. However, the optimal implant type remains debated. Third-generation IM nails, including proximal femoral nail antirotation (PFNA), Gamma 3 (G3), and Intertan (IT), feature helical blades, single lag screws, and dual integrated lag screws, respectively. This meta-analysis evaluates functional outcomes, healing status, and complication rates of intertrochanteric fractures treated with these devices.

Methods: A systematic review and meta-analysis were conducted using PubMed, Embase, CENTRAL, and Google Scholar until November 2024. Randomized controlled trials (RCTs) and observational comparative studies involving patients older than 65 years were included. Outcomes assessed functional scores, healing status, and complications.

Results: Twenty-four studies (6 RCTs, 5 prospective cohort studies, and 13 retrospective cohort studies) involving 2,999 patients were analyzed. The G3, IT, and PFNA groups included 617, 1,124, and 1,258 patients, respectively. Results showed similar functional recovery across devices. Perioperative parameters favored PFNA, while IT demonstrated lower complication and revision rates. No outcomes favored G3, suggesting it is interchangeable with other devices. PFNA was easier to use and required shorter operation times but had higher cutout and revision rates. IT, despite longer operation times, promoted faster fracture healing and had fewer complications. G3 did not outperform other devices in any measured outcome.

Conclusion: PFNA, G3, and IT provide comparable functional outcomes and overall complication rates, making device selection largely dependent on surgeon preference. However, IT may be the superior choice for complex fractures requiring more excellent stability due to its lower complication and revision rates. This analysis highlights the importance of tailoring implant selection to individual patient needs and fracture complexity.

Level of evidence: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.

背景:老年人粗隆间骨折的治疗面临着重大挑战,髓内钉(IM)越来越多地用于固定。然而,最佳种植体类型仍有争议。第三代IM钉,包括股骨近端防旋钉(PFNA), Gamma 3 (G3)和Intertan (IT),分别具有螺旋刀片,单螺钉和双集成螺钉。本荟萃分析评估了使用这些装置治疗转子间骨折的功能结局、愈合状况和并发症发生率。方法:到2024年11月,使用PubMed、Embase、CENTRAL和谷歌Scholar进行系统评价和荟萃分析。随机对照试验(rct)和观察性比较研究纳入了年龄大于65岁的患者。结果评估了功能评分、愈合状况和并发症。结果:共分析了24项研究(6项随机对照试验、5项前瞻性队列研究和13项回顾性队列研究),涉及2999例患者。G3、IT和PFNA组分别包括617例、1124例和1258例患者。结果显示不同设备的功能恢复相似。围手术期参数倾向于PFNA,而IT表现出较低的并发症和翻修率。没有结果支持G3,这表明它可以与其他设备互换。PFNA更容易使用,所需的手术时间更短,但切割和翻修率更高。尽管手术时间较长,但IT促进骨折愈合更快,并发症更少。G3在任何测量结果中都没有优于其他设备。结论:PFNA、G3和IT提供了相当的功能结果和总体并发症发生率,使得器械的选择在很大程度上取决于外科医生的偏好。然而,对于需要更好稳定性的复杂骨折,IT可能是更好的选择,因为它的并发症和翻修率较低。这一分析强调了根据患者个体需求和骨折复杂性定制植入物选择的重要性。证据等级:治疗性III级。有关证据水平的完整描述,请参见作者说明。
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引用次数: 0
Postoperative Foot Drop After Spinal Surgery: Etiology, Presentation, and Management Strategies. 脊柱术后足下垂:病因、表现和管理策略。
IF 2.4 Q2 SURGERY Pub Date : 2025-03-25 eCollection Date: 2025-03-01 DOI: 10.2106/JBJS.RVW.24.00191
Bryce A Basques, Alejandro Perez-Albela, John Hanna, Ashley Knebel, Mohammad Daher, Manjot Singh, Eren O Kuris, Alan H Daniels

» The incidence of postoperative foot drop after spine surgery is estimated at 3.33%, with higher rates reported in complex procedures such as high-grade spondylolisthesis correction (up to 30%). Risk factors include disc-space distraction, deformity corrections, prolonged surgery, and advanced patient age.» The primary mechanisms of postoperative foot drop include direct nerve trauma, stretch injuries from retraction or distraction, compression from hematomas or implants, and ischemic damage because of disrupted blood flow.» Preoperative counseling, intraoperative precision, appropriate disc space distraction, and careful nerve retraction are key to mitigating the risk of foot drop, with ongoing research needed to standardize preventive and management guidelines.» Treatment strategies are tailored to the underlying cause, ranging from conservative options (physical therapy, ankle-foot orthoses, and functional electrical stimulation) to surgical interventions (hematoma evacuation, implant removal, neurolysis, nerve transfer, and tendon transfer), although outcomes are highly variable.

脊柱手术后足下垂的发生率估计为3.33%,在复杂的手术中,如高度椎体滑脱矫正,发生率更高(高达30%)。危险因素包括椎间盘间隙撑开、畸形矫正、手术时间延长和患者年龄增大。»术后足下垂的主要机制包括直接神经损伤、牵回或牵张造成的拉伸损伤、血肿或植入物造成的压迫以及血流中断造成的缺血性损伤。»术前咨询、术中精确、适当的椎间盘间隙撑开和小心的神经牵伸是减轻足下垂风险的关键,需要持续的研究来标准化预防和管理指南。»治疗策略是根据潜在原因量身定制的,从保守选择(物理治疗、踝足矫形器和功能性电刺激)到手术干预(血肿清除、植入物移除、神经松解术、神经转移和肌腱转移),尽管结果变化很大。
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引用次数: 0
Anterior Cervical Discectomy and Fusion vs. Anterior Cervical Corpectomy and Fusion for 2-Level Degenerative Cervical Myelopathy: A Systematic Review and Meta-Analysis. 前路颈椎椎间盘切除术和融合vs.前路颈椎椎体切除术和融合治疗2节段退行性颈椎病:系统回顾和荟萃分析。
IF 2.4 Q2 SURGERY Pub Date : 2025-03-25 eCollection Date: 2025-03-01 DOI: 10.2106/JBJS.RVW.24.00204
Aman Verma, Anil Kumar, Utsav Anand, Siddharth Sekhar Sethy, Aakash Jain, Vibhor Abrol, Kaustubh Ahuja, Bhaskar Sarkar, Pankaj Kandwal

Background: Cervical spondylotic myelopathy (CSM) is a common cause of progressive neurological decline in elderly patients, often necessitating surgical decompression. Anterior cervical discectomy and fusion (ACDF) and anterior cervical corpectomy and fusion (ACCF) are commonly used procedures. However, there is no consensus on the superior approach, particularly in cases involving 2-level CSM.

Methods: A systematic review and meta-analysis were conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. PubMed, Cochrane, Scopus, and Embase databases were searched for studies comparing perioperative, clinical, and radiological outcomes of ACDF and ACCF in 2-level CSM. Fourteen studies with 4,449 patients (ACDF: 2,265, ACCF: 2,184) met the inclusion criteria. Outcomes analyzed included operating (OR) time, blood loss, hospital stay, patient-reported outcomes (Neck Disability Index [NDI], Visual Analog Scale [VAS], modified Japanese Orthopaedic Association [mJOA], Odom criteria), radiological parameters, complications, and fusion rates. Statistical analysis was performed using Review Manager 5.4, with heterogeneity assessed using I2 statistics.

Results: ACDF was associated with significantly shorter OR time, reduced blood loss, shorter hospital stays, and lower overall complication rates compared with ACCF. Both procedures showed comparable improvements in NDI, VAS, and mJOA scores. ACDF demonstrated superior postoperative cervical alignment, with greater improvements in global and segmental lordosis. Complication rates, including implant-related issues, were higher in the ACCF group, while reoperation and fusion rates were similar.

Conclusion: Both ACDF and ACCF significantly improve functional outcomes in 2-level CSM. However, ACDF demonstrated advantages in perioperative outcomes, complications, and cervical alignment. While ACDF is associated with shorter OR time and fewer complications, ACCF may be necessary in cases with extensive disk herniation or other pathologies requiring direct decompression posterior to the vertebral body. Surgical decisions should be individualized based on patient-specific pathology.

Level of evidence: Level II. See Instructions for Authors for a complete description of levels of evidence.

背景:脊髓型颈椎病(CSM)是老年患者进行性神经功能衰退的常见原因,通常需要手术减压。前路颈椎椎间盘切除术融合术(ACDF)和前路颈椎椎体切除术融合术(ACCF)是常用的手术。然而,对于哪种方法更好,特别是两层CSM的病例,并没有一致的意见。方法:根据系统评价和元分析指南的首选报告项目进行系统评价和元分析。检索PubMed、Cochrane、Scopus和Embase数据库,比较ACDF和ACCF在2级CSM患者围手术期、临床和放射学结果的研究。14项研究4449例患者(ACDF: 2265例,ACCF: 2184例)符合纳入标准。结果分析包括手术(OR)时间、出血量、住院时间、患者报告的结果(颈部残疾指数(NDI)、视觉模拟量表(VAS)、修正日本骨科协会(mJOA)、奥多姆标准)、放射学参数、并发症和融合率。使用Review Manager 5.4进行统计分析,使用I2统计量评估异质性。结果:与ACCF相比,ACDF显着缩短了手术室时间,减少了出血量,缩短了住院时间,降低了总并发症发生率。两种方法在NDI、VAS和mJOA评分方面均显示出可比性的改善。ACDF显示出更好的术后颈椎直线,整体和节段性前凸有更大的改善。并发症发生率,包括种植体相关问题,在ACCF组较高,而再手术率和融合率相似。结论:ACDF和ACCF均能显著改善2级CSM的功能结局。然而,ACDF在围手术期结局、并发症和颈椎对齐方面显示出优势。虽然ACDF与更短的手术时间和更少的并发症相关,但对于广泛的椎间盘突出或其他需要椎体后部直接减压的病变,ACCF可能是必要的。手术决定应根据患者的具体病理进行个体化。证据等级:二级。有关证据水平的完整描述,请参见作者说明。
{"title":"Anterior Cervical Discectomy and Fusion vs. Anterior Cervical Corpectomy and Fusion for 2-Level Degenerative Cervical Myelopathy: A Systematic Review and Meta-Analysis.","authors":"Aman Verma, Anil Kumar, Utsav Anand, Siddharth Sekhar Sethy, Aakash Jain, Vibhor Abrol, Kaustubh Ahuja, Bhaskar Sarkar, Pankaj Kandwal","doi":"10.2106/JBJS.RVW.24.00204","DOIUrl":"10.2106/JBJS.RVW.24.00204","url":null,"abstract":"<p><strong>Background: </strong>Cervical spondylotic myelopathy (CSM) is a common cause of progressive neurological decline in elderly patients, often necessitating surgical decompression. Anterior cervical discectomy and fusion (ACDF) and anterior cervical corpectomy and fusion (ACCF) are commonly used procedures. However, there is no consensus on the superior approach, particularly in cases involving 2-level CSM.</p><p><strong>Methods: </strong>A systematic review and meta-analysis were conducted according to Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. PubMed, Cochrane, Scopus, and Embase databases were searched for studies comparing perioperative, clinical, and radiological outcomes of ACDF and ACCF in 2-level CSM. Fourteen studies with 4,449 patients (ACDF: 2,265, ACCF: 2,184) met the inclusion criteria. Outcomes analyzed included operating (OR) time, blood loss, hospital stay, patient-reported outcomes (Neck Disability Index [NDI], Visual Analog Scale [VAS], modified Japanese Orthopaedic Association [mJOA], Odom criteria), radiological parameters, complications, and fusion rates. Statistical analysis was performed using Review Manager 5.4, with heterogeneity assessed using I2 statistics.</p><p><strong>Results: </strong>ACDF was associated with significantly shorter OR time, reduced blood loss, shorter hospital stays, and lower overall complication rates compared with ACCF. Both procedures showed comparable improvements in NDI, VAS, and mJOA scores. ACDF demonstrated superior postoperative cervical alignment, with greater improvements in global and segmental lordosis. Complication rates, including implant-related issues, were higher in the ACCF group, while reoperation and fusion rates were similar.</p><p><strong>Conclusion: </strong>Both ACDF and ACCF significantly improve functional outcomes in 2-level CSM. However, ACDF demonstrated advantages in perioperative outcomes, complications, and cervical alignment. While ACDF is associated with shorter OR time and fewer complications, ACCF may be necessary in cases with extensive disk herniation or other pathologies requiring direct decompression posterior to the vertebral body. Surgical decisions should be individualized based on patient-specific pathology.</p><p><strong>Level of evidence: </strong>Level II. See Instructions for Authors for a complete description of levels of evidence.</p>","PeriodicalId":47098,"journal":{"name":"JBJS Reviews","volume":"13 3","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143701790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Complications Associated with Surgical Management of Olecranon Fractures: A Systematic Review. 鹰嘴骨折手术治疗的并发症:系统回顾。
IF 2.4 Q2 SURGERY Pub Date : 2025-03-25 eCollection Date: 2025-03-01 DOI: 10.2106/JBJS.RVW.24.00163
Mikhail A Bethell, Eoghan T Hurley, Harvey Allen, Jay M Levin, Christopher S Klifto, Oke Anakwenze, Malcolm R DeBaun, Christian A Péan

Purpose: The purpose of this study was to systematically review the literature to assess surgical complications following surgical management of olecranon fractures.

Methods: A literature search of MEDLINE, Embase, and the Cochrane Library was performed based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Clinical studies reporting complications following olecranon fracture management were included. The complication profile of plate fixation (PF), screw fixation, and tension band wiring (TBW) was recorded. Implant removal rates were considered independent of complication rates.

Results: Eighty-six studies were included in the analysis, with 5,161 patients who underwent an olecranon fracture treatment with an average age of 50.2 years (range, 7.4-88.8) and an average follow-up of 30.8 months (range, 3-218). The majority of studies used PF (58.1%). Screw fixation had higher implant complications than PF (5.9% vs 3.0%, p < 0.001), and PF had the highest percentage of musculoskeletal complications (3.6%, p <0.001) and wound complications (4.8%, p = 0.048). Nerve complications were similar among the 3 surgical options (p = 0.233). PF had the lowest complication rate (12.6%, p < 0.001), while screw fixation had the lowest reoperation (8.6%, p < 0.001) and implant removal rates (6.2%, p < 0.001). The overall complication rate for TBW was 18.4%, with loss of reduction being the most common complications occurring in 2.8% of patients.

Conclusion: PF demonstrated lower overall complications compared with screw fixation, with increased rates of symptomatic implants requiring removal which contributed to higher reoperation rates. TBW demonstrated an inferior complication profile compared with both modern fixation options. Further research should expand on the limited comparative studies between screw and PF.

Level of evidence: Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.

目的:本研究的目的是系统地回顾文献,以评估手术治疗鹰嘴骨折后的手术并发症。方法:根据系统评价和meta分析指南的首选报告项目,对MEDLINE、Embase和Cochrane图书馆进行文献检索。临床研究报告了鹰嘴骨折处理后的并发症。记录钢板固定(PF)、螺钉固定和张力带钢丝(TBW)的并发症情况。种植体移除率与并发症发生率无关。结果:86项研究纳入分析,5161例患者接受鹰嘴骨折治疗,平均年龄50.2岁(范围7.4-88.8),平均随访时间30.8个月(范围3-218)。大多数研究使用PF(58.1%)。螺钉固定的植入物并发症高于PF (5.9% vs 3.0%, p < 0.001), PF的肌肉骨骼并发症比例最高(3.6%,p)。结论:与螺钉固定相比,PF的总体并发症更低,有症状的植入物需要移除的比例增加,这有助于更高的再手术率。与两种现代固定方式相比,TBW表现出较低的并发症。进一步的研究应扩大螺钉与pf之间有限的比较研究。证据水平:治疗性III级。有关证据水平的完整描述,请参见作者说明。
{"title":"Complications Associated with Surgical Management of Olecranon Fractures: A Systematic Review.","authors":"Mikhail A Bethell, Eoghan T Hurley, Harvey Allen, Jay M Levin, Christopher S Klifto, Oke Anakwenze, Malcolm R DeBaun, Christian A Péan","doi":"10.2106/JBJS.RVW.24.00163","DOIUrl":"10.2106/JBJS.RVW.24.00163","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to systematically review the literature to assess surgical complications following surgical management of olecranon fractures.</p><p><strong>Methods: </strong>A literature search of MEDLINE, Embase, and the Cochrane Library was performed based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Clinical studies reporting complications following olecranon fracture management were included. The complication profile of plate fixation (PF), screw fixation, and tension band wiring (TBW) was recorded. Implant removal rates were considered independent of complication rates.</p><p><strong>Results: </strong>Eighty-six studies were included in the analysis, with 5,161 patients who underwent an olecranon fracture treatment with an average age of 50.2 years (range, 7.4-88.8) and an average follow-up of 30.8 months (range, 3-218). The majority of studies used PF (58.1%). Screw fixation had higher implant complications than PF (5.9% vs 3.0%, p < 0.001), and PF had the highest percentage of musculoskeletal complications (3.6%, p <0.001) and wound complications (4.8%, p = 0.048). Nerve complications were similar among the 3 surgical options (p = 0.233). PF had the lowest complication rate (12.6%, p < 0.001), while screw fixation had the lowest reoperation (8.6%, p < 0.001) and implant removal rates (6.2%, p < 0.001). The overall complication rate for TBW was 18.4%, with loss of reduction being the most common complications occurring in 2.8% of patients.</p><p><strong>Conclusion: </strong>PF demonstrated lower overall complications compared with screw fixation, with increased rates of symptomatic implants requiring removal which contributed to higher reoperation rates. TBW demonstrated an inferior complication profile compared with both modern fixation options. Further research should expand on the limited comparative studies between screw and PF.</p><p><strong>Level of evidence: </strong>Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.</p>","PeriodicalId":47098,"journal":{"name":"JBJS Reviews","volume":"13 3","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143701803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genetics and Epigenetics of Legg-Calvé-Perthes Disease. legg - calv<s:1> - perthes病的遗传学和表观遗传学。
IF 2.4 Q2 SURGERY Pub Date : 2025-03-25 eCollection Date: 2025-03-01 DOI: 10.2106/JBJS.RVW.24.00209
Bshara Sleem, Jad Abdul Khalek, Karim Kanbar, Elio Bitar, Pablo Castaneda, Karim Masrouha

» Multifactorial Pathogenesis: Legg-Calvé-Perthes disease (LCPD) may result from a complex interplay of genetic, epigenetic, and environmental factors, culminating in avascular necrosis of the femoral head in children aged 4 to 10 years.» Genetic Contributions: Mutations in COL2A1 weaken cartilage integrity, and polymorphisms in IL6 drive inflammatory responses, exacerbating bone resorption and necrosis.» Role of Epigenetics: Epigenetic mechanisms, such as altered DNA methylation and miRNA dysregulation, may modulate disease progression by linking genetic susceptibility to environmental influences.» Environmental Amplifiers: Key environmental risk factors, including maternal smoking, low birth weight, and socioeconomic deprivation, may exacerbate the genetic and epigenetic predisposition to LCPD.» Future Directions: Advancements in genetic screening and epigenetic therapies, such as miRNA modulators and DNA methylation inhibitors, combined with preventive measures like improved prenatal care and reduced smoke exposure, may offer promising avenues for optimizing outcomes in LCPD.

"多因素发病机制:莱格-卡尔维-珀尔特氏病(LCPD)可能是遗传、表观遗传和环境因素复杂相互作用的结果,最终导致 4 至 10 岁儿童股骨头无血管性坏死"。遗传因素:COL2A1的突变会削弱软骨的完整性,而IL6的多态性会驱动炎症反应,加剧骨吸收和坏死"。表观遗传学的作用:表观遗传学机制,如 DNA 甲基化改变和 miRNA 失调,可通过将遗传易感性与环境影响联系起来来调节疾病的进展。环境放大器:关键的环境风险因素,包括母亲吸烟、出生体重过轻和社会经济贫困,可能会加剧 LCPD 的遗传和表观遗传易感性"。未来方向:基因筛查和表观遗传疗法(如 miRNA 调节剂和 DNA 甲基化抑制剂)的进步,再加上改善产前护理和减少烟雾暴露等预防措施,可能会为优化 LCPD 的治疗效果提供有希望的途径。
{"title":"Genetics and Epigenetics of Legg-Calvé-Perthes Disease.","authors":"Bshara Sleem, Jad Abdul Khalek, Karim Kanbar, Elio Bitar, Pablo Castaneda, Karim Masrouha","doi":"10.2106/JBJS.RVW.24.00209","DOIUrl":"10.2106/JBJS.RVW.24.00209","url":null,"abstract":"<p><p>» Multifactorial Pathogenesis: Legg-Calvé-Perthes disease (LCPD) may result from a complex interplay of genetic, epigenetic, and environmental factors, culminating in avascular necrosis of the femoral head in children aged 4 to 10 years.» Genetic Contributions: Mutations in COL2A1 weaken cartilage integrity, and polymorphisms in IL6 drive inflammatory responses, exacerbating bone resorption and necrosis.» Role of Epigenetics: Epigenetic mechanisms, such as altered DNA methylation and miRNA dysregulation, may modulate disease progression by linking genetic susceptibility to environmental influences.» Environmental Amplifiers: Key environmental risk factors, including maternal smoking, low birth weight, and socioeconomic deprivation, may exacerbate the genetic and epigenetic predisposition to LCPD.» Future Directions: Advancements in genetic screening and epigenetic therapies, such as miRNA modulators and DNA methylation inhibitors, combined with preventive measures like improved prenatal care and reduced smoke exposure, may offer promising avenues for optimizing outcomes in LCPD.</p>","PeriodicalId":47098,"journal":{"name":"JBJS Reviews","volume":"13 3","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143701807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Health Policy Challenges and Reforms: Critical Updates for Orthopaedic Surgeons. 卫生政策的挑战和改革:骨科医生的关键更新。
IF 2.4 Q2 SURGERY Pub Date : 2025-02-17 eCollection Date: 2025-02-01 DOI: 10.2106/JBJS.RVW.24.00192
Peter Boufadel, Mohamad Y Fares, Mohammad Daher, Abhay Mathur, Patrick Saunders, Joseph A Abboud, Hafiz F Kassam

» Medicare reimbursement: Physician payments have declined 29% since 2001, straining practice sustainability. Proposed legislation (H.R. 2474) could align payments with inflation, although concerns persist about its fiscal impact on Medicare.» Medicare advantage: These plans provide benefits such as cost caps and premium-free options for patients, but increase administrative burdens, delay care, and restrict provider networks for physicians.» Prior authorization: Intended to ensure appropriate care and control costs, prior authorization frequently delays treatment, raises administrative workloads, and contributes to physician burnout. Proposed reforms aim to balance efficiency and oversight.» Noncompete clauses: Advocates argue noncompete clauses protect healthcare investments, but critics highlight their role in limiting physician mobility, disrupting patient care, and reducing competition. Legal challenges to a federal ban add uncertainty.» Physician-owned hospitals: Supporters emphasize physician-owned hospitals' high-quality care and competitive benefits, whereas detractors warn of risks such as conflicts of interest, inequities in patient access, and strain on community hospitals.» Advancing nonopioid pain management: Nonopioid strategies reduce dependency risks and improve recovery but may require additional resources and upfront costs. Policies such as the Non-Opioids Prevent Addiction in the Nation Act aim to incentivize their use.

医疗保险报销:自2001年以来,医生支付的费用下降了29%,使医疗业务的可持续性受到影响。拟议的立法(H.R. 2474)可能会使支付与通货膨胀挂钩,尽管人们仍然担心它对医疗保险的财政影响。»医疗保险优势:这些计划为患者提供成本上限和免保费选择等福利,但增加了行政负担,延误了护理,并限制了医生的提供者网络。»事先授权:为了确保适当的护理和控制成本,事先授权经常延误治疗,增加行政工作量,并导致医生倦怠。拟议中的改革旨在平衡效率和监督。»竞业禁止条款:支持者认为,竞业禁止条款保护医疗投资,但批评者强调,它们在限制医生的流动性,扰乱患者护理,减少竞争中的作用。联邦禁令面临的法律挑战增加了不确定性。医生所有的医院:支持者强调医生所有的医院的高质量的护理和竞争性的福利,而批评者警告风险,如利益冲突,患者获取的不公平,以及对社区医院的压力。推进非阿片类药物疼痛管理:非阿片类药物策略可降低依赖风险并改善康复,但可能需要额外的资源和前期成本。《非阿片类药物预防成瘾国家法案》等政策旨在激励它们的使用。
{"title":"Health Policy Challenges and Reforms: Critical Updates for Orthopaedic Surgeons.","authors":"Peter Boufadel, Mohamad Y Fares, Mohammad Daher, Abhay Mathur, Patrick Saunders, Joseph A Abboud, Hafiz F Kassam","doi":"10.2106/JBJS.RVW.24.00192","DOIUrl":"10.2106/JBJS.RVW.24.00192","url":null,"abstract":"<p><p>» Medicare reimbursement: Physician payments have declined 29% since 2001, straining practice sustainability. Proposed legislation (H.R. 2474) could align payments with inflation, although concerns persist about its fiscal impact on Medicare.» Medicare advantage: These plans provide benefits such as cost caps and premium-free options for patients, but increase administrative burdens, delay care, and restrict provider networks for physicians.» Prior authorization: Intended to ensure appropriate care and control costs, prior authorization frequently delays treatment, raises administrative workloads, and contributes to physician burnout. Proposed reforms aim to balance efficiency and oversight.» Noncompete clauses: Advocates argue noncompete clauses protect healthcare investments, but critics highlight their role in limiting physician mobility, disrupting patient care, and reducing competition. Legal challenges to a federal ban add uncertainty.» Physician-owned hospitals: Supporters emphasize physician-owned hospitals' high-quality care and competitive benefits, whereas detractors warn of risks such as conflicts of interest, inequities in patient access, and strain on community hospitals.» Advancing nonopioid pain management: Nonopioid strategies reduce dependency risks and improve recovery but may require additional resources and upfront costs. Policies such as the Non-Opioids Prevent Addiction in the Nation Act aim to incentivize their use.</p>","PeriodicalId":47098,"journal":{"name":"JBJS Reviews","volume":"13 2","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143442321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Mechanisms and Safety of Corticosteroid Injections in Orthopaedic Surgery. 骨科手术中皮质类固醇注射的机制和安全性。
IF 2.4 Q2 SURGERY Pub Date : 2025-02-12 eCollection Date: 2025-02-01 DOI: 10.2106/JBJS.RVW.24.00177
Jonathan J Light, Mitchell P John, Kevin F Bonner, Joseph F Styron

» Corticosteroid injections (CSIs), including intra-articular, perineural, and those involving tendon sheaths or bursae, offer potential relief from osteoarthritic and inflammatory musculoskeletal pain, including gout attacks, as well as tarsal tunnel syndrome, plantar fasciitis, and interdigital neuromas.» CSI for musculoskeletal pain is commonly used as a nonoperative management option for both diagnostic and therapeutic purposes, offering pain relief, typically lasting from days to months.» CSIs are often performed prior to surgery as part of the nonoperative management of many conditions, with multiple CSIs within the year of surgery increasing postoperative infection risk in some major joints.» Despite the potential benefits of CSI, there are risks, including a potential increase in the risk of surgical site infection secondary to bacterial contamination and the immunomodulating effect of corticosteroids when given in the perioperative period.» To date, a multitude of studies across orthopaedic subspecialties has reported on perioperative infection risk associated with CSIs. However, heterogeneity in study design and patient populations has made standardized recommendations challenging. It is, therefore, difficult to elucidate, with a high level of evidence, the most appropriate perioperative timeline for CSI administration for which infection risk is nonsignificant.

»皮质类固醇注射(CSIs),包括关节内、神经周围和涉及肌腱鞘或滑囊的注射,可以潜在地缓解骨关节炎和炎症性肌肉骨骼疼痛,包括痛风发作,以及跗骨隧道综合征、足底筋膜炎和指间神经瘤。对于肌肉骨骼疼痛,CSI通常被用作诊断和治疗目的的非手术治疗选择,提供疼痛缓解,通常持续数天至数月。»CSIs通常在手术前进行,作为许多疾病非手术治疗的一部分,手术后一年内多次CSIs会增加一些主要关节的术后感染风险。»尽管CSI有潜在的益处,但也存在风险,包括可能增加继发于细菌污染的手术部位感染风险,以及围手术期给予皮质类固醇的免疫调节作用。迄今为止,骨科亚专科的大量研究报告了与CSIs相关的围手术期感染风险。然而,研究设计和患者群体的异质性使得标准化推荐具有挑战性。因此,很难用高水平的证据来阐明感染风险不显著的CSI给药的最合适的围手术期时间。
{"title":"The Mechanisms and Safety of Corticosteroid Injections in Orthopaedic Surgery.","authors":"Jonathan J Light, Mitchell P John, Kevin F Bonner, Joseph F Styron","doi":"10.2106/JBJS.RVW.24.00177","DOIUrl":"10.2106/JBJS.RVW.24.00177","url":null,"abstract":"<p><p>» Corticosteroid injections (CSIs), including intra-articular, perineural, and those involving tendon sheaths or bursae, offer potential relief from osteoarthritic and inflammatory musculoskeletal pain, including gout attacks, as well as tarsal tunnel syndrome, plantar fasciitis, and interdigital neuromas.» CSI for musculoskeletal pain is commonly used as a nonoperative management option for both diagnostic and therapeutic purposes, offering pain relief, typically lasting from days to months.» CSIs are often performed prior to surgery as part of the nonoperative management of many conditions, with multiple CSIs within the year of surgery increasing postoperative infection risk in some major joints.» Despite the potential benefits of CSI, there are risks, including a potential increase in the risk of surgical site infection secondary to bacterial contamination and the immunomodulating effect of corticosteroids when given in the perioperative period.» To date, a multitude of studies across orthopaedic subspecialties has reported on perioperative infection risk associated with CSIs. However, heterogeneity in study design and patient populations has made standardized recommendations challenging. It is, therefore, difficult to elucidate, with a high level of evidence, the most appropriate perioperative timeline for CSI administration for which infection risk is nonsignificant.</p>","PeriodicalId":47098,"journal":{"name":"JBJS Reviews","volume":"13 2","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Osteotomies of the Knee for Valgus Malalignment. 膝关节外翻错位的截骨术。
IF 2.4 Q2 SURGERY Pub Date : 2025-02-12 eCollection Date: 2025-02-01 DOI: 10.2106/JBJS.RVW.24.00189
Nicholas Bertha, Miranda G Manfre, Garwin Chin, Adam Peszek, Alexis J Batiste, Travis G Maak, Rachel M Frank

» Osteotomy is an effective treatment strategy for young, active patients with symptomatic valgus malalignment of the knee that has been unresponsive to conservative management.» Osteotomies are also indicated to support joint preservation procedures, such as lateral meniscus allograft transplantation and/or cartilage restoration to the lateral compartment, in the valgus malaligned patient, even if the malalignment is subtle.» Techniques to correct valgus include lateral opening wedge distal femoral osteotomy (LOWDFO), medial closing wedge distal femoral osteotomy (MCWDFO), lateral opening wedge high tibial osteotomy (LOWHTO), or medial closing wedge high tibial osteotomy (MCWHTO). The specific technique chosen depends on surgeon preference, concomitant procedures, and deformity location (femoral, tibial, or both).» Each approach comes with its own advantages and disadvantages. LOWDFO offers easier correction for larger deformities but has a higher risk of nonunion, while MCWDFO facilitates faster time to union but is more technically demanding. For those with a tibial-based deformity, LOWHTO carries a higher risk of nonunion, MCWHTO may lead to medial collateral ligament laxity or patella baja, and both may cause alterations of the tibial slope and may be limited as an isolated procedure in severe deformity correction.» Irrespective of the surgical approach, the outcomes of these procedures are generally favorable, improving patient-reported outcomes and potentially delaying the need for total knee arthroplasty. However, it is crucial to carefully select the appropriate procedure based on the patient's anatomy and the specificities of their valgus deformity to ensure the best possible results.

对于保守治疗无效的年轻活跃患者,截骨术是一种有效的治疗策略。对于外翻错位患者,即使错位很轻微,也可采用骨切除术来支持关节保护手术,如外侧半月板同种异体移植和/或外侧间室软骨修复。»纠正外翻的技术包括外侧开口楔形股骨远端截骨术(LOWDFO),内侧闭合楔形股骨远端截骨术(MCWDFO),外侧开口楔形胫骨高位截骨术(LOWHTO)或内侧闭合楔形胫骨高位截骨术(MCWHTO)。具体技术的选择取决于外科医生的偏好、伴随手术和畸形位置(股骨、胫骨或两者)。每种方法都有自己的优点和缺点。LOWDFO对于较大的畸形更容易矫正,但不愈合的风险更高,而MCWDFO有助于更快的愈合时间,但技术要求更高。对于那些以胫骨为基础的畸形,低whto具有较高的不愈合风险,MCWHTO可能导致内侧副韧带松弛或髌骨下压,两者都可能导致胫骨斜度的改变,并且可能在严重畸形矫正中作为孤立手术受到限制。无论采用何种手术方式,这些手术的结果通常是有利的,改善了患者报告的结果,并有可能推迟全膝关节置换术的需要。然而,根据患者的解剖结构和外翻畸形的特点仔细选择合适的手术是至关重要的,以确保最好的结果。
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