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Calibration and recalibration of stress response systems across development: Implications for mental and physical health. 整个发展过程中应激反应系统的校准和再校准:对身心健康的影响。
2区 医学 Q1 Medicine Pub Date : 2022-01-01 Epub Date: 2022-06-29 DOI: 10.1016/bs.acdb.2022.03.001
Megan R Gunnar, Mariann A Howland

Decades of human and animal research demonstrates that stress responsive neuroendocrine systems calibrate to the harshness of environmental conditions during fetal and early postnatal life. Emerging evidence indicates that if conditions change markedly over childhood, the hypothalamic pituitary adrenal (HPA) axis may recalibrate during puberty, another period that involves heightened neural plasticity and rapid maturation of neurobehavioral systems. These recent findings have prompted increased interest in the potential for stress system calibration/recalibration over development. To direct research in this area, this chapter integrates and discusses theoretical perspectives and empirical evidence pertaining to calibration and recalibration of the stress response. We describe how these concepts relate to other constructs, including sensitive periods, plasticity, and programming. We then consider four potential periods of calibration/recalibration: fetal, infancy, puberty, and pregnancy/lactation. In each section, we discuss evidence that the HPA and/or sympathetic medullary adrenal (SAM) system undergoes developmental change, rendering it more plastic and amenable to shift its activity in response to environmental conditions. We also review findings that the impacts of environmental harshness on stress responding persist beyond these periods. We then articulate that marked change in the quality of the environment (from harsh to benign or vice versa) is required in order for recalibration to occur, and that recalibration would result in shifts in stress responding to more closely align with the profiles of individuals who have experienced these conditions throughout life. Finally, we reflect on whether recalibration of the HPA and SAM system may extend to the other stress-responsive neurobehavioral systems.

数十年的人类和动物研究表明,应激反应神经内分泌系统在胎儿和产后早期的生活中对环境条件的恶劣程度进行了校准。新出现的证据表明,如果情况在儿童时期发生显著变化,下丘脑-垂体-肾上腺(HPA)轴可能会在青春期重新调整,这是另一个涉及神经可塑性增强和神经行为系统快速成熟的时期。这些最近的发现促使人们对应力系统校准/再校准的潜力越来越感兴趣。为了指导这一领域的研究,本章整合并讨论了与应力反应的校准和再校准有关的理论观点和经验证据。我们描述了这些概念如何与其他结构相关,包括敏感期、可塑性和编程。然后我们考虑四个可能的校准/重新校准时期:胎儿期、婴儿期、青春期和妊娠期/哺乳期。在每一节中,我们讨论HPA和/或交感髓样肾上腺(SAM)系统经历发育变化的证据,使其更具可塑性,并可根据环境条件改变其活动。我们还回顾了环境严酷对压力反应的影响持续超过这些时期的研究结果。然后,我们阐明,环境质量的显著变化(从恶劣到良性或反之亦然)是重新校准发生的必要条件,重新校准将导致压力响应的变化,与一生中经历过这些条件的个体的轮廓更紧密地一致。最后,我们思考了HPA和SAM系统的重新校准是否可以扩展到其他应激反应神经行为系统。
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引用次数: 2
Parental sexual orientation, parental gender identity, and the development of children. 父母的性取向,父母的性别认同,和孩子的发展。
2区 医学 Q1 Medicine Pub Date : 2022-01-01 Epub Date: 2022-04-22 DOI: 10.1016/bs.acdb.2022.03.002
Charlotte J Patterson

In recent years, many lesbian, gay, bisexual, transgender, and queer (LGBTQ+) adults have become parents. LGBTQ+ parenthood does, however, remain a controversial topic across the United States and around the world. Several questions have been raised. For instance, to what extent do LGBTQ+ adults make capable parents? Do children who have LGBTQ+ parents grow up in healthy ways? What factors contribute to positive family functioning in families with LGBTQ+ parents? A growing body of social science research has addressed these questions, and the findings suggest both that LGBTQ+ adults are successful in their roles as parents and that their children develop in positive ways. Overall, the findings to date suggest that parental sexual orientation and gender identity do not in themselves determine success in parenting or child development; indeed, sexual and gender minority parents and their children have shown remarkable resilience, even in the face of many challenges. Contextual issues, as well as implications of research findings for law and policy around the world are discussed.

近年来,许多女同性恋、男同性恋、双性恋、变性人和酷儿(LGBTQ+)成年人已经为人父母。然而,LGBTQ+父母身份在美国和世界各地仍然是一个有争议的话题。人们提出了几个问题。例如,LGBTQ+成年人在多大程度上能成为称职的父母?有LGBTQ+父母的孩子会健康成长吗?哪些因素有助于LGBTQ+父母家庭的积极家庭功能?越来越多的社会科学研究解决了这些问题,研究结果表明,LGBTQ+成年人成功地扮演了父母的角色,他们的孩子也以积极的方式发展。总的来说,迄今为止的研究结果表明,父母的性取向和性别认同本身并不决定育儿或儿童发展的成功;事实上,即使面对许多挑战,性和性别少数群体的父母和他们的孩子也表现出了非凡的韧性。背景问题,以及研究结果对法律和政策在世界各地的影响进行了讨论。
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引用次数: 1
New Methods and Approaches for Studying Child Development 研究儿童发展的新方法和新途径
2区 医学 Q1 Medicine Pub Date : 2022-01-01 DOI: 10.1016/s0065-2407(22)x0002-5
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引用次数: 0
Why do we have three rational number notations? The importance of percentages. 为什么我们有三个有理数符号?百分比的重要性。
2区 医学 Q1 Medicine Pub Date : 2022-01-01 Epub Date: 2022-06-06 DOI: 10.1016/bs.acdb.2022.05.001
Robert S Siegler, Jing Tian

The integrated theory of numerical development provides a unified approach to understanding numerical development, including acquisition of knowledge about whole numbers, fractions, decimals, percentages, negatives, and relations among all of these types of numbers (Siegler, Thompson, & Schneider, 2011). Although, considerable progress has been made toward many aspects of this integration (Siegler, Im, Schiller, Tian, & Braithwaite, 2020), the role of percentages has received much less attention than that of the other types of numbers. This chapter is an effort to redress this imbalance by reporting data on understanding of percentages and their relations to other types of numbers. We first describe the integrated theory; then summarize what is known about development of understanding of whole numbers, fractions, and decimals; then describe recent progress in understanding the role of percentages; and finally consider instructional implications of the theory and research.

数值发展的综合理论提供了一种理解数值发展的统一方法,包括获得关于整数、分数、小数、百分比、负数以及所有这些类型的数字之间关系的知识(Siegler, Thompson, & Schneider, 2011)。尽管在这种整合的许多方面已经取得了相当大的进展(Siegler, Im, Schiller, Tian, & Braithwaite, 2020),但百分比的作用受到的关注远远少于其他类型的数字。本章通过报告对百分比及其与其他类型数字的关系的理解的数据,努力纠正这种不平衡。我们首先描述了整合理论;然后总结关于理解整数、分数和小数的发展的已知情况;然后描述最近在理解百分比的作用方面的进展;最后考虑理论和研究的教学意义。
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引用次数: 1
Preface. 前言。
2区 医学 Q1 Medicine Pub Date : 2022-01-01 DOI: 10.1016/S0065-2407(22)00033-7
Jeffrey J Lockman
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引用次数: 0
Using temporal network methods to reveal the idiographic nature of development. 利用时间网络方法揭示发展的特质。
2区 医学 Q1 Medicine Pub Date : 2022-01-01 Epub Date: 2021-12-28 DOI: 10.1016/bs.acdb.2021.11.003
Natasha Chaku, Adriene M Beltz

Averages dominate developmental science: There are representative groups, mean trajectories, and generalizations to typical children. Nearly all parents and teachers, however, eagerly proclaim that few youth are average; each child, adolescent, and young adult is unique. Indeed, individual youth are the focus of many eminent developmental theories, yet there is a shocking paucity of developmental methods-including study designs and analysis techniques-that truly afford individual-level inferences. Thus, the goal of this chapter is to explicate the advantages of an idiographic approach to developmental science, that is, an approach that provides insight into individual youth, often by studying within-person variation in intensive longitudinal data, such as densely coded observations, repeated daily or momentary assessments, and functional neuroimages. In three domains across development, the chapter illustrates the benefits of an idiographic approach by comparing empirical conclusions offered by traditional mean-based analysis techniques versus techniques that leverage the temporal and individualized nature of intensive longitudinal data. The chapter then concentrates on group iterative multiple model estimation (GIMME), which is an analysis technique that uses intensive longitudinal data to create youth-specific temporal networks, detailing how brain regions or behaviors are directionally related across time. The promise of GIMME is exemplified by applications to three different domains across development. The chapter closes by encouraging future idiographic developmental science to consider how research questions, study designs, and data analyses can be formed, implemented, and conducted in ways that optimize inferences about individual-not average-youth.

平均数主导着发展科学:有代表性的群体、平均轨迹和对典型儿童的概括。然而,几乎所有的家长和教师都急切地宣称,很少有青少年是平均水平;每个儿童、青少年和年轻成人都是独一无二的。事实上,青少年个体是许多著名发展理论的研究重点,但真正能提供个体水平推论的发展方法(包括研究设计和分析技术)却少得令人震惊。因此,本章的目标是阐释发展科学中特异性方法的优势,即通过研究密集纵向数据(如密集编码观察、重复的日常或瞬间评估以及功能神经图像)中的人内变异来深入了解青少年个体的方法。本章通过比较传统的基于平均值的分析技术与利用密集纵向数据的时间性和个性化特点的技术所得出的经验性结论,说明了在整个发展过程中的三个领域中采用特异性分析方法的好处。然后,本章重点介绍了群体迭代多重模型估计(GIMME),这是一种利用密集纵向数据创建青少年特定时间网络的分析技术,详细说明了大脑区域或行为在不同时间的方向性关联。GIMME 在三个不同发展领域的应用充分体现了它的前景。本章最后鼓励未来的特异性发展科学考虑如何形成、实施和进行研究问题、研究设计和数据分析,以优化对个体而非平均青少年的推断。
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引用次数: 0
Young children's cooperation and conflict with other children. 幼儿与其他孩子的合作与冲突。
2区 医学 Q1 Medicine Pub Date : 2022-01-01 Epub Date: 2022-06-07 DOI: 10.1016/bs.acdb.2022.04.004
Dale F Hay, Amy Paine, Charlotte Robinson

Early forms of cooperation and conflict feature regularly in young children's interactions with other people. However, these two types of social interaction are only rarely studied together in the same sample. In this chapter we review studies of cooperation and conflict in children under 3 years of age, with a particular focus on peer interaction. Only a few studies examined cooperation and conflict in parallel. To illustrate how conflict and cooperation can be studied simultaneously, we present findings from a longitudinal study of social development, in which previously unacquainted toddlers were observed during laboratory birthday parties. These analyses revealed that the two types of interaction are positively associated and provide opportunities for young children to refine their social skills.

早期形式的合作和冲突经常出现在幼儿与其他人的互动中。然而,这两种类型的社会互动很少在同一样本中一起研究。在本章中,我们回顾了3岁以下儿童的合作和冲突研究,特别关注同伴互动。只有少数研究同时考察了合作和冲突。为了说明如何同时研究冲突和合作,我们提出了一项关于社会发展的纵向研究的结果,在这项研究中,我们在实验室的生日派对上观察了以前不认识的幼儿。这些分析表明,这两种类型的互动是积极相关的,并为幼儿提供了完善社交技能的机会。
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引用次数: 0
Using big data from long-form recordings to study development and optimize societal impact. 利用长格式录音中的大数据研究发展并优化社会影响。
2区 医学 Q1 Medicine Pub Date : 2021-08-06 DOI: 10.31219/osf.io/ybqfw
M. Cychosz, Alejandrina Cristia
Big data are everywhere. In this chapter, we focus on one source: long-form, child-centered recordings collected using wearable technologies. Because these recordings are simultaneously unobtrusive and encompassing, they may be a breakthrough technology for clinicians and researchers from several diverse fields. We demonstrate this possibility by outlining three applications for the recordings-clinical treatment, large-scale interventions, and language documentation-where we see the greatest potential. We argue that incorporating these recordings into basic and applied research will result in more equitable treatment of patients, more reliable measurements of the effects of interventions on real-world behavior, and deeper scientific insights with less observational bias. We conclude by outlining a proposal for a semistructured online platform where vast numbers of long-form recordings could be hosted and more representative, less biased algorithms could be trained.
大数据无处不在。在本章中,我们关注一个来源:使用可穿戴技术收集的以儿童为中心的长格式录音。由于这些记录既不引人注目又包罗万象,因此对于来自多个不同领域的临床医生和研究人员来说,它们可能是一项突破性技术。我们通过概述临床治疗记录、大规模干预和语言文档的三种应用来证明这种可能性,在这些应用中我们看到了最大的潜力。我们认为,将这些记录纳入基础和应用研究将使患者得到更公平的治疗,对干预措施对现实世界行为的影响进行更可靠的测量,并以更少的观察偏差获得更深入的科学见解。最后,我们概述了一个半结构化在线平台的建议,在该平台上可以托管大量的长格式记录,并可以训练更具代表性、更少偏见的算法。
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引用次数: 1
An interactionist perspective on the development of coordinated social attention. 关于协调社会注意力发展的互动主义观点。
2区 医学 Q1 Medicine Pub Date : 2021-01-04 DOI: 10.31234/osf.io/s5tgz
S. Hoehl, B. Bertenthal
Infants' ability to coordinate their attention with other people develops profoundly across the first year of life. Mainly based on experimental research focusing on infants' behavior under highly controlled conditions, developmental milestones were identified and explained in the past by prominent theories in terms of the onset of specific cognitive skills. In contrast to this approach, recent longitudinal research challenges this perspective with findings suggesting that social attention develops continuously with a gradual refinement of skills. Informed by these findings, we argue for an interactionist and dynamical systems view that bases observable advances in infant social attention skills on increasingly fine-tuned mutual adjustments in the caregiver-infant dyad, resulting in gradually improving mutual prediction. We present evidence for this view from recent studies leveraging new technologies which afford the opportunity to dynamically track social interactions in real-time. These new technically-sophisticated studies offer unprecedented insights into the dynamic processes of infant-caregiver social attention. It is now possible to track in much greater detail fluctuations over time with regard to object-directed attention as well as social attention and how these processes relate to one another. Encouraged by these initial results and new insights from this interactionist developmental social neuroscience approach, we conclude with a "call to action" in which we advocate for more ecologically valid paradigms for studying social attention as a dynamic and bi-directional process.
婴儿与他人协调注意力的能力在出生的第一年得到了深刻的发展。主要基于专注于婴儿在高度受控条件下行为的实验研究,过去在特定认知技能的开始方面,著名的理论已经确定并解释了发育里程碑。与这种方法相反,最近的纵向研究对这一观点提出了挑战,研究结果表明,社会注意力随着技能的逐渐完善而不断发展。根据这些发现,我们主张一种互动主义和动态系统的观点,该观点将婴儿社交注意力技能的可观察到的进步建立在照顾者和婴儿二人组中日益微调的相互调整之上,从而逐步改善相互预测。我们从最近利用新技术的研究中为这一观点提供了证据,这些新技术提供了实时动态跟踪社交互动的机会。这些新的技术复杂的研究为婴儿护理者社会关注的动态过程提供了前所未有的见解。现在可以更详细地跟踪对象导向注意力和社会注意力随时间的波动,以及这些过程如何相互关联。在这些初步结果和这种互动主义发展社会神经科学方法的新见解的鼓舞下,我们以“行动呼吁”结束,在该呼吁中,我们倡导更具生态有效性的范式,将社会注意力作为一个动态和双向的过程来研究。
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引用次数: 6
Neonatal sleep development and early learning in infants with prenatal opioid exposure. 产前阿片类药物暴露婴儿的新生儿睡眠发育和早期学习。
2区 医学 Q1 Medicine Pub Date : 2021-01-01 Epub Date: 2020-09-15 DOI: 10.1016/bs.acdb.2020.07.001
Nicole A Heller, Hira Shrestha, Deborah G Morrison, Katrina M Daigle, Beth A Logan, Jonathan A Paul, Mark S Brown, Marie J Hayes

The aim of this chapter is to examine the role of sleep and cognition in the context of the cumulative risk model examining samples of at-risk infants and maternal-infant dyads. The cumulative risk model posits that non-optimal developmental outcomes are the result of multiple factors in a child's life including, but not limited to, prenatal teratogenic exposures, premature birth, family socioeconomic status, parenting style and cognitions as well as the focus of this volume, sleep. We highlight poor neonatal sleep as both an outcome of perinatal risk as well as a risk factor to developing attentional and cognitive capabilities during early childhood. Outcomes associated with and contributing to poor sleep and cognition during infancy are examined in relation to other known risks in our clinical population. Implications of this research and recommendations for interventions for this population are provided.

本章的目的是在累积风险模型的背景下研究睡眠和认知的作用,该模型研究了高危婴儿和母婴双体的样本。累积风险模型认为,非最佳发育结果是儿童生活中多种因素的结果,包括但不限于产前致畸暴露、早产、家庭社会经济地位、父母教养方式和认知,以及本卷的重点——睡眠。我们强调新生儿睡眠不良既是围产期风险的结果,也是儿童早期发展注意力和认知能力的风险因素。在我们的临床人群中,与婴儿期睡眠和认知不良相关的结果与其他已知风险进行了研究。本研究的意义和建议的干预措施,为这一人群提供。
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引用次数: 2
期刊
Advances in Child Development and Behavior
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