Pub Date : 2021-01-01DOI: 10.36648/1590-8577.21.22.58-59
K. Shailaja
We report a rare case of an Undifferentiated Carcinoma of Pancreas (UCP) in a 21-year-young man, who presented with painless jaundice, dyspnea and dry cough. Weight loss for one month. No history of fever. It constitutes less than 1% of pancreatic exocrine neoplasia. Its histopathologic properties remain poorly understood. LFT shows mild increase in transaminases and alakalinephosatase. However, CA19.9 and serum electrolytes were normal. Imaging studies revealed a lobulated solid hypo enhancing mass noted in the pancreatic duodenal groove encasing the common hepatic artery, gastroduodenal artery and partly encasing main portal vein with likely involvement of part of the head and uncinate process of pancreas measuring 6.6 × 4.3 × 3.5 cm in the head of the pancreas. A EUS guided Fine Needle Biopsy (FNB) was performed and microscopy showed a cellular neoplasm composed of pleomorphic mononuclear cells (IMP3-positive; LCA, and CD68 negative) and occasional multinucleated giant cells (LCA, and CD68-positive; pancytokeratin, and EMA-negative) consistent with UCP. Evidence supports that the giant cells are non-neoplastic and of histiocytic origin.
{"title":"A Case Report of Undifferentiated Pancreatic Carcinoma","authors":"K. Shailaja","doi":"10.36648/1590-8577.21.22.58-59","DOIUrl":"https://doi.org/10.36648/1590-8577.21.22.58-59","url":null,"abstract":"We report a rare case of an Undifferentiated Carcinoma of Pancreas (UCP) in a 21-year-young man, who presented with painless jaundice, dyspnea and dry cough. Weight loss for one month. No history of fever. It constitutes less than 1% of pancreatic exocrine neoplasia. Its histopathologic properties remain poorly understood. LFT shows mild increase in transaminases and alakalinephosatase. However, CA19.9 and serum electrolytes were normal. Imaging studies revealed a lobulated solid hypo enhancing mass noted in the pancreatic duodenal groove encasing the common hepatic artery, gastroduodenal artery and partly encasing main portal vein with likely involvement of part of the head and uncinate process of pancreas measuring 6.6 × 4.3 × 3.5 cm in the head of the pancreas. A EUS guided Fine Needle Biopsy (FNB) was performed and microscopy showed a cellular neoplasm composed of pleomorphic mononuclear cells (IMP3-positive; LCA, and CD68 negative) and occasional multinucleated giant cells (LCA, and CD68-positive; pancytokeratin, and EMA-negative) consistent with UCP. Evidence supports that the giant cells are non-neoplastic and of histiocytic origin.","PeriodicalId":47280,"journal":{"name":"Journal of the Pancreas","volume":"22 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69688553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.36648/1590-8577.21.22.119-120
J. Gershman
{"title":"New Pancreatic Cancer Treatments","authors":"J. Gershman","doi":"10.36648/1590-8577.21.22.119-120","DOIUrl":"https://doi.org/10.36648/1590-8577.21.22.119-120","url":null,"abstract":"","PeriodicalId":47280,"journal":{"name":"Journal of the Pancreas","volume":"22 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69688841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.36648/1590-8577.21.S4.002
U. Divya
{"title":"Laparoscopic resection of a metastatic duodenal paraganglioma in an adolescent","authors":"U. Divya","doi":"10.36648/1590-8577.21.S4.002","DOIUrl":"https://doi.org/10.36648/1590-8577.21.S4.002","url":null,"abstract":"","PeriodicalId":47280,"journal":{"name":"Journal of the Pancreas","volume":"123 21 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69689052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.36648/1590-8577.21.S5.06-08
D. Coco, S. Leanza
The results of meta-analytic review that compared Laparoscopic Distal Pancreatectomy (LDP) versus Robotic Distal Pancreatectomy (RDP) demonstrated the safety and feasibility of the robotic approach. The studies comparison showed no differences in postoperative complications, 30-day mortality, ICU stay, conversion rate, pancreatic fistula,morbidity and mortality rate between the LPD group and the RDP group.
{"title":"Laparoscopic versus Robotic Distal Pancreatectomy: review","authors":"D. Coco, S. Leanza","doi":"10.36648/1590-8577.21.S5.06-08","DOIUrl":"https://doi.org/10.36648/1590-8577.21.S5.06-08","url":null,"abstract":"The results of meta-analytic review that compared Laparoscopic Distal Pancreatectomy (LDP) versus Robotic Distal Pancreatectomy (RDP) demonstrated the safety and feasibility of the robotic approach. The studies comparison showed no differences in postoperative complications, 30-day mortality, ICU stay, conversion rate, pancreatic fistula,morbidity and mortality rate between the LPD group and the RDP group.","PeriodicalId":47280,"journal":{"name":"Journal of the Pancreas","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69689619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.36648/1590-8577.22.3.80-84
B. Fern, es Nadaleto, F. R. A. Torrez, A. Goldenberg, P. F. D. C. Carvalho, R. A. Neto, G. D'Ippolito, E. Lobo
Primary pancreatic lymphoma is a rare form of extranodal malignant lymphoma. Most cases show a diffuse large B-cell immunophenotype. Hereby we describe the case of a 62-year-old man that was admitted in the emergency department of Sao Paulo Hospital with abdominal pain, weight loss and jaundice. Imaging exams showed a bulky resectable tumour in the pancreatic head. The patient underwent pancreatoduodenectomy and the histopathological analysis showed an primary pancreatic T-cell lymphoma. He received chemotherapy and subsequent autologous stem-cell transplantation. He presented a complete remission with no evidence of disease in the 8-months follow up. Literature review on this disease recommends the diagnostic to be done with endoscopic or percutaneous biopsy and the best treatment choice is systemic therapy, but evidence is scarce. There are few cases of T-cell primary pancreatic lymphoma described in the literature, with a worse prognosis compared to other immunophenotypes
{"title":"Primary Pancreatic T-Cell Lymphoma - A Case Report and Literature Review","authors":"B. Fern, es Nadaleto, F. R. A. Torrez, A. Goldenberg, P. F. D. C. Carvalho, R. A. Neto, G. D'Ippolito, E. Lobo","doi":"10.36648/1590-8577.22.3.80-84","DOIUrl":"https://doi.org/10.36648/1590-8577.22.3.80-84","url":null,"abstract":"Primary pancreatic lymphoma is a rare form of extranodal malignant lymphoma. Most cases show a diffuse large B-cell immunophenotype. Hereby we describe the case of a 62-year-old man that was admitted in the emergency department of Sao Paulo Hospital with abdominal pain, weight loss and jaundice. Imaging exams showed a bulky resectable tumour in the pancreatic head. The patient underwent pancreatoduodenectomy and the histopathological analysis showed an primary pancreatic T-cell lymphoma. He received chemotherapy and subsequent autologous stem-cell transplantation. He presented a complete remission with no evidence of disease in the 8-months follow up. Literature review on this disease recommends the diagnostic to be done with endoscopic or percutaneous biopsy and the best treatment choice is systemic therapy, but evidence is scarce. There are few cases of T-cell primary pancreatic lymphoma described in the literature, with a worse prognosis compared to other immunophenotypes","PeriodicalId":47280,"journal":{"name":"Journal of the Pancreas","volume":"22 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69690030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.36648/1590-8577.22.3.85-89
Bo Xiao, Zhi-qiong Jiang
Introduction Central pontine myelinolysis (CPM) is a rare osmotic demyelination syndrome. Myelinolysis following patients with acute pancreatitis (AP) is extremely rare. To the best of our knowledge, only two cases have been reported in prior literatures. However, the associated mechanisms on patients with CPM secondary to AP have remained unclear. Patient concerns (1) A 58-year-old woman, with upper abdomen pain complicating nausea and vomiting for ten days, had a fever and abdominal pain (first hospitalization). (2) On second hospitalization, she was in abdominal pain and distension. (3) On third hospitalization, she was admitted because of "intense diarrhea for two days and drowsiness for half a day". On the eighth day, the patient deteriorated with onset of anisocoria. On the 12th hospital day, patient’s mental status became conscious but in a new-onset mutism. Diagnosis (1) Contrast-enhanced CT revealed a severe acute necrotic pancreatitis (first hospitalization). (2) On second hospitalization, laboratory tests showed a glucose of 12.3 mmol/L and a hyponatremia of 125.9 mmol/L. Follow-up CT showed the presence of abdominal infection. (3) On third hospitalization, laboratory findings included a hypokalemia of 2.4 mmol/L, a severe hypernatremia of 192 mmol/L and a severe hyperchloremia of 150 mmol/L, and a creatinine of 118.7umol/L. Brain MRI, performed 4.5 months after acute-onset, revealed the central pontine myelinolysis. Interventions (1) She received intravenous fluids and insulin treatment, initiated electrolyte corrections, and anti-infection (first hospitalization). (2) On second hospitalization, the operation including pancreatic abscess removal and cholecystectomy was performed around 2.5 months after AP onset. (3) On third hospitalization, she received potassium and fluid infusions, diuresis, and continuous renal replacement therapy. Electrolyte corrections were continuously proceeded. Outcomes When she was discharged from third hospitalization, the patient was in unconsciousness with a lethargy status. By means of telephone follow-up, the patient died five days after the third discharge. Conclusion It is important to raise the early diagnosis of CPM in AP patients (especially severe necrotic pancreatitis) if severe electrolyte disturbance and subsequently altered mental status or transient anisocoria occur. Based on high specificity imaging findings, MRI should be performed in time when delayed onset of CPM is suspected.
{"title":"Delayed Onset of Central Pontine Myelinolysis: A Rare Presentation Following Surgery for Severe Acute Necrotic Pancreatitis Complicating Infection","authors":"Bo Xiao, Zhi-qiong Jiang","doi":"10.36648/1590-8577.22.3.85-89","DOIUrl":"https://doi.org/10.36648/1590-8577.22.3.85-89","url":null,"abstract":"Introduction Central pontine myelinolysis (CPM) is a rare osmotic demyelination syndrome. Myelinolysis following patients with acute pancreatitis (AP) is extremely rare. To the best of our knowledge, only two cases have been reported in prior literatures. However, the associated mechanisms on patients with CPM secondary to AP have remained unclear. Patient concerns (1) A 58-year-old woman, with upper abdomen pain complicating nausea and vomiting for ten days, had a fever and abdominal pain (first hospitalization). (2) On second hospitalization, she was in abdominal pain and distension. (3) On third hospitalization, she was admitted because of \"intense diarrhea for two days and drowsiness for half a day\". On the eighth day, the patient deteriorated with onset of anisocoria. On the 12th hospital day, patient’s mental status became conscious but in a new-onset mutism. Diagnosis (1) Contrast-enhanced CT revealed a severe acute necrotic pancreatitis (first hospitalization). (2) On second hospitalization, laboratory tests showed a glucose of 12.3 mmol/L and a hyponatremia of 125.9 mmol/L. Follow-up CT showed the presence of abdominal infection. (3) On third hospitalization, laboratory findings included a hypokalemia of 2.4 mmol/L, a severe hypernatremia of 192 mmol/L and a severe hyperchloremia of 150 mmol/L, and a creatinine of 118.7umol/L. Brain MRI, performed 4.5 months after acute-onset, revealed the central pontine myelinolysis. Interventions (1) She received intravenous fluids and insulin treatment, initiated electrolyte corrections, and anti-infection (first hospitalization). (2) On second hospitalization, the operation including pancreatic abscess removal and cholecystectomy was performed around 2.5 months after AP onset. (3) On third hospitalization, she received potassium and fluid infusions, diuresis, and continuous renal replacement therapy. Electrolyte corrections were continuously proceeded. Outcomes When she was discharged from third hospitalization, the patient was in unconsciousness with a lethargy status. By means of telephone follow-up, the patient died five days after the third discharge. Conclusion It is important to raise the early diagnosis of CPM in AP patients (especially severe necrotic pancreatitis) if severe electrolyte disturbance and subsequently altered mental status or transient anisocoria occur. Based on high specificity imaging findings, MRI should be performed in time when delayed onset of CPM is suspected.","PeriodicalId":47280,"journal":{"name":"Journal of the Pancreas","volume":"22 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69690043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.36648/1590-8577.21.22.172-175
Swedha Varma
Fundamentally Speaking, the human pancreas comprises of two organs in one: an exocrine organ and an endocrine organ. The exocrine organ is comprised of pancreatic acinar cells and pipe cells that produce stomach related chemicals and sodium bicarbonate, separately. The essential capacity of the exocrine pancreas is to discharge the stomach related chemicals answerable for ordinary processing and ingestion of every day staples, lastly absorption of supplements into our body.
{"title":"Tumor-related paraneoplastic disorder creating a bogus synapse?","authors":"Swedha Varma","doi":"10.36648/1590-8577.21.22.172-175","DOIUrl":"https://doi.org/10.36648/1590-8577.21.22.172-175","url":null,"abstract":"Fundamentally Speaking, the human pancreas comprises of two organs in one: an exocrine organ and an endocrine organ. The exocrine organ is comprised of pancreatic acinar cells and pipe cells that produce stomach related chemicals and sodium bicarbonate, separately. The essential capacity of the exocrine pancreas is to discharge the stomach related chemicals answerable for ordinary processing and ingestion of every day staples, lastly absorption of supplements into our body.","PeriodicalId":47280,"journal":{"name":"Journal of the Pancreas","volume":"22 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69688544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.36648/1590-8577.22.1.21-27
Hyginus N Arua, F. Idigo, Chioma L. Arua
Background Abdominal ultrasound and computed tomography (CT) utilization in pancreatic imaging has been found invaluable in the evaluation of pancreatic lesions. Although the gold standard modality for imaging of pancreas, CT is fraught with the limitations of radiation risk, cost and availability. Ultrasound (US) imaging of the pancreas is cost effective, readily available with no radiation risk but it is operator-dependent and limited by bowel gas. Comparative study of CT and US biometry of pancreas in normal adult population in Lagos State Nigeria has not been established. Method A prospective cross-sectional study of 150 apparently normal adult patients who underwent both CT scan and ultrasonography (US) at Clinix Healthcare Ilupeju, Lagos State, and who met the inclusion criteria, was carried out. Anterior-posterior (AP) dimensions of the pancreatic head, body and tail were obtained at right angles to the longitudinal axis of the organ. Results On US, the mean AP dimensions of the pancreas head, body, and tail in the studied population were 25.10 ± 2.75 mm, 15.98 ± 1.86 mm, and 13.50 ± 1.53mm respectively. On CT, the mean ± SD AP pancreas dimensions of head, body, and tail in the studied population were 26.77 ± 2.68 mm, 21.19 ± 2.12 mm, and 17.25 ± 2.12mm respectively. Conclusion AP dimensions of the pancreas segments measured on CT were significantly larger than that measured on US (P= 0.000), and CT is better modality in demonstration of pancreas segments especially the tail.
{"title":"Correlation of Ultrasound and Computed Tomography Measurements of the Pancreas in a Normal Adult Nigerian Population","authors":"Hyginus N Arua, F. Idigo, Chioma L. Arua","doi":"10.36648/1590-8577.22.1.21-27","DOIUrl":"https://doi.org/10.36648/1590-8577.22.1.21-27","url":null,"abstract":"Background Abdominal ultrasound and computed tomography (CT) utilization in pancreatic imaging has been found invaluable in the evaluation of pancreatic lesions. Although the gold standard modality for imaging of pancreas, CT is fraught with the limitations of radiation risk, cost and availability. Ultrasound (US) imaging of the pancreas is cost effective, readily available with no radiation risk but it is operator-dependent and limited by bowel gas. Comparative study of CT and US biometry of pancreas in normal adult population in Lagos State Nigeria has not been established. Method A prospective cross-sectional study of 150 apparently normal adult patients who underwent both CT scan and ultrasonography (US) at Clinix Healthcare Ilupeju, Lagos State, and who met the inclusion criteria, was carried out. Anterior-posterior (AP) dimensions of the pancreatic head, body and tail were obtained at right angles to the longitudinal axis of the organ. Results On US, the mean AP dimensions of the pancreas head, body, and tail in the studied population were 25.10 ± 2.75 mm, 15.98 ± 1.86 mm, and 13.50 ± 1.53mm respectively. On CT, the mean ± SD AP pancreas dimensions of head, body, and tail in the studied population were 26.77 ± 2.68 mm, 21.19 ± 2.12 mm, and 17.25 ± 2.12mm respectively. Conclusion AP dimensions of the pancreas segments measured on CT were significantly larger than that measured on US (P= 0.000), and CT is better modality in demonstration of pancreas segments especially the tail.","PeriodicalId":47280,"journal":{"name":"Journal of the Pancreas","volume":"22 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69689422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.36648/1590-8577.21.S4.005
Sahithi Podela
{"title":"Implications for Treatment of Pancreatic Cancer","authors":"Sahithi Podela","doi":"10.36648/1590-8577.21.S4.005","DOIUrl":"https://doi.org/10.36648/1590-8577.21.S4.005","url":null,"abstract":"","PeriodicalId":47280,"journal":{"name":"Journal of the Pancreas","volume":"23 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69689741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.36648/1590-8577.22.3.90-92
Xianqiang Yu
Teratoma is a common germ cell tumor, which most cases can be diagnosed by imaging examination. At present, surgical treatment is the main treatment method, but the occurrence of teratoma in some cases brings lots of trouble. Our case was a 2-month-old baby boy with abdominal distension as main manifestation at the beginning, and was diagnosed by CT as a large mass in the left abdomen (teratoma). The mass adjoined closely to the pancreas and brought much complexity for surgical excision. We therefore share with our colleagues the surgical experience of this particular case. Surgical excision of intraperitoneal complex teratoma is the key to radical cure of the tumor.
{"title":"Surgical Management of Neonatal Parapancreatic Giant Teratoma","authors":"Xianqiang Yu","doi":"10.36648/1590-8577.22.3.90-92","DOIUrl":"https://doi.org/10.36648/1590-8577.22.3.90-92","url":null,"abstract":"Teratoma is a common germ cell tumor, which most cases can be diagnosed by imaging examination. At present, surgical treatment is the main treatment method, but the occurrence of teratoma in some cases brings lots of trouble. Our case was a 2-month-old baby boy with abdominal distension as main manifestation at the beginning, and was diagnosed by CT as a large mass in the left abdomen (teratoma). The mass adjoined closely to the pancreas and brought much complexity for surgical excision. We therefore share with our colleagues the surgical experience of this particular case. Surgical excision of intraperitoneal complex teratoma is the key to radical cure of the tumor.","PeriodicalId":47280,"journal":{"name":"Journal of the Pancreas","volume":"22 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69690225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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