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Management of Pathological Dental Attrition in Prader-Willi Syndrome: A Case Report Using the Personalized Radboud Strategy. Prader-Willi综合征病理性牙磨耗的处理:使用个性化Radboud策略的一例报告。
IF 1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-01 DOI: 10.1111/scd.70149
Hoda Tayebi-Hillali, Pablo Fernández Alonso, Berta Rivas-Mundiña, Mercedes Outumuro Rial, Márcio Diniz-Freitas, Javier Fernández Feijoo

Prader-Willi syndrome (PWS) is a rare genetic disorder characterized by obesity, hypotonia, intellectual disability, and behavioral disturbances that complicate dental management. Parafunctional habits such as bruxism often lead to severe tooth wear, while cooperation and anesthesia represent additional challenges. A 34-year-old woman with genetically confirmed PWS presented with generalized dental wear, poor oral hygiene, and multiple carious lesions. Preventive and splint therapies were initially proposed but not feasible. Two years later, she returned with pain due to pulp exposure. Because of limited cooperation and comorbidities, dental treatment under general anesthesia was planned in two sessions, including molar extractions and multiple root canal treatments. Complete acrylic dentures with metal reinforcement were fabricated, restoring vertical dimension, improving esthetics, and serving as protective splints. Caregivers were instructed on hygiene, and annual follow-up was established. After six years, bone atrophy and further wear were noted, but the patient continued using relined prostheses without sedation. This case demonstrates that a resolutive, interdisciplinary approach can successfully manage complex dental problems in PWS. General anesthesia minimized the number of interventions while ensuring comprehensive care. Reinforced acrylic dentures provided a functional, aesthetic, and cost-effective solution, despite the progressive nature of dental wear and bone loss.

普瑞德-威利综合征(PWS)是一种罕见的遗传性疾病,其特征是肥胖、张力低下、智力残疾和行为障碍,使牙科治疗复杂化。磨牙等非功能性习惯经常导致严重的牙齿磨损,而合作和麻醉则是额外的挑战。34岁女性,遗传确诊PWS,表现为全身性牙齿磨损,口腔卫生差,多发龋齿。预防性和夹板治疗最初被提出,但不可行。两年后,她因牙髓暴露而疼痛复发。由于合作有限和合并症,全麻下的牙科治疗计划分为两次,包括磨牙拔牙和多根管治疗。制作金属补强全丙烯酸义齿,修复垂直尺寸,改善美观,并起到保护夹板的作用。对护理人员进行卫生指导,并建立年度随访。六年后,骨萎缩和进一步磨损被注意到,但患者继续使用有绳假体,没有镇静。这个案例表明,一个果断的,跨学科的方法可以成功地管理复杂的牙齿问题在PWS。全身麻醉减少了干预的次数,同时保证了全面的护理。增强丙烯酸假牙提供了一个功能,美观,成本效益的解决方案,尽管牙齿磨损和骨质流失的进行性性质。
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引用次数: 0
Etiology of Hypomineralized Second Primary Molars: A Systematic Review. 第二磨牙低矿化的病因:系统综述。
IF 1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-01 DOI: 10.1111/scd.70139
Atika Bouabid, Rihab Mabrouk, Selsebil Laajimi, Yamina Elelmi, Fatma Masmoudi, Ahlem Baaziz

Objectives: Hypomineralized Second Primary Molars (HSPM) are qualitative enamel defects that typically involve one to four second primary molars. Although widely investigated, their etiology remains unclear. This review synthesizes current evidence on potential etiological factors.

Materials and methods: The design of this systematic review complied with the 2020 PRISMA guidelines. The research was conducted using five databases. Study quality and bias were assessed using the Newcastle-Ottawa Scale.

Results: Nine articles met the inclusion criteria, underscoring the limited evidence base. Prenatal factors were most frequently associated with HSPM, particularly epigenetic markers in blood (DNA hypermethylation and hypomethylation, p < 0.05), maternal smoking (p = 0.001), and maternal illness (p < 0.001). Though effect sizes varied, and methodological heterogeneity limited comparability. Perinatal factors such as preterm birth (p = 0.024) and delivery complications (p = 0.032) were also reported, but evidence was less robust and often confounded by small sample sizes. Postnatal factors, including recurrent childhood illnesses (asthma, otitis media, episodes of fever, and eczema) were significantly linked to HSPM, yet causality remains uncertain given the dependence on retrospective designs and parent-reported data.

Conclusions: Current evidence suggests that HSPM is likely multifactorial with contributions from prenatal, perinatal, and postnatal exposures. However, the overall level of evidence is moderate, constrained by small study numbers, variable quality, low response rate, and the retrospective nature of the studies. Stronger conclusions will require large-scale, prospective studies with standardized diagnostic criteria and rigorous control of bias.

目的:低矿化第二磨牙(HSPM)是一种质性牙釉质缺陷,通常涉及1 - 4颗第二磨牙。虽然广泛调查,但其病因尚不清楚。这篇综述综合了目前关于潜在病因的证据。材料和方法:本系统评价的设计符合2020 PRISMA指南。这项研究使用了五个数据库。使用纽卡斯尔-渥太华量表评估研究质量和偏倚。结果:9篇文章符合纳入标准,证据基础有限。产前因素最常与HSPM相关,特别是血液中的表观遗传标记(DNA高甲基化和低甲基化,p < 0.05)、母亲吸烟(p = 0.001)和母亲疾病(p < 0.001)。虽然效果大小不同,方法的异质性限制了可比性。围产期因素,如早产(p = 0.024)和分娩并发症(p = 0.032)也有报道,但证据不太有力,而且经常因样本量小而混淆。出生后的因素,包括儿童复发性疾病(哮喘、中耳炎、发热和湿疹发作)与HSPM显著相关,但由于依赖于回顾性设计和父母报告的数据,因果关系仍不确定。结论:目前的证据表明,HSPM可能是多因素的,与产前、围产期和产后暴露有关。然而,由于研究数量少、质量不稳定、反应率低以及研究的回顾性,证据的总体水平是中等的。更有力的结论将需要大规模的、具有标准化诊断标准和严格控制偏倚的前瞻性研究。
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引用次数: 0
Comparative Evaluation of Three Different Toothbrushing Teaching Interventions in Improving Oral Hygiene in Autistic Children Aged 7-15 Years-A Randomized Clinical Trial. 3种不同刷牙教学干预对7 ~ 15岁自闭症儿童口腔卫生改善的比较评价——随机临床试验。
IF 1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-01 DOI: 10.1111/scd.70142
Lakshika Sree Vimalchand, Daya Srinivasan, Akshayakumar Senthamilselvan, Dhaarane Santhakumar

Aim and background: Addressing oral hygiene in children with autism remains a critical concern for dental professionals and caregivers. These challenges make routine toothbrushing difficult and increase the risk of oral health problems. Recognizing the urgent need for practical solutions, this investigation was undertaken to evaluate three structured toothbrushing teaching interventions and their effectiveness among autistic children.

Materials and methods: This study evaluated the effectiveness of three instructional methods-visual posters, video demonstrations, and caregiver modeling to improve oral hygiene in autistic children aged 7-15 years. Sixty participants were randomly divided into three groups. Toothbrushing skills, cooperation (Frankl Scale), and oral hygiene (OHI-S) were assessed over 3 months.

Results: All groups showed significant improvement. Parent Modeling (15.55 ± 1.23) was highly superior to both Video and Poster groups (p < 0.001). A statistically significant difference (p = 0.024) was also found favoring the Video (12.80 ± 1.20) over the Poster (10.75 ± 2.49) group.

Conclusion: Caregiver modeling was the most effective method for teaching toothbrushing to children with ASD, promoting better outcomes in both oral hygiene and behavioural cooperation.

Trial registration: CTRI/2025/03/083547.

目的和背景:解决自闭症儿童的口腔卫生问题仍然是牙科专业人员和护理人员关注的关键问题。这些挑战使日常刷牙变得困难,并增加了口腔健康问题的风险。认识到迫切需要切实可行的解决方案,本调查进行了评估三结构化的刷牙教学干预措施及其在自闭症儿童中的效果。材料和方法:本研究评估了视觉海报、视频演示和照顾者模型三种教学方法对改善7-15岁自闭症儿童口腔卫生的效果。60名参与者被随机分为三组。在3个月内对刷牙技巧、配合度(Frankl量表)和口腔卫生(OHI-S)进行评估。结果:各组均有明显改善。Parent Modeling组(15.55±1.23)显著优于Video组和Poster组(p < 0.001)。Video组(12.80±1.20)优于Poster组(10.75±2.49),差异有统计学意义(p = 0.024)。结论:照顾者建模是ASD儿童刷牙教学最有效的方法,在口腔卫生和行为合作方面均有较好的效果。试验报名:CTRI/2025/03/083547。
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引用次数: 0
Mindfulness-Based Orofacial Pain Education and Management Program: A Qualitative Analysis of Transgender Participants' Perceptions. 基于正念的口腔面部疼痛教育和管理项目:跨性别参与者感知的定性分析。
IF 1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-01 DOI: 10.1111/scd.70141
Melissa de Oliveira Melchior, Beatriz Dorne, Alex Moreira Mélo, Nadyne Saab Messias, Victor Hugo Alves Ribeiro-Silva, Lucas Gaspar Ribeiro, Lúcia Alves da Silva-Lara, Christie Ramos Andrade Leite-Panissi, Edilaine Cristina da Silva Gherardi-Donato, Jardel Francisco Mazzi-Chaves, Laís Valencise Magri

Introduction: Transgender individuals are disproportionately affected by temporomandibular disorders (TMDs), often compounded by psychosocial stressors and limited access to affirming healthcare. Conventional TMD treatments may fall short in addressing the emotional and behavioral components of chronic orofacial pain, underscoring the need for integrative interventions. This study aimed to explore the implementation and perceived impact of a Mindfulness-Based Orofacial Pain Education Program as a complementary approach for transgender individuals with TMD.

Methods: A qualitative design was employed, using weekly instructor reports and a post-intervention focus group with transgender participants (ages 24-39), each diagnosed with TMD according to the DC/TMD criteria. Over eight weeks, participants attended weekly 60-min sessions incorporating mindfulness practices, pain education, and self-management strategies. Data sources included 8 weekly instructor audio reports (n = 32 recordings) and one focus group interview (duration: 68 min). All transcriptions were analyzed using Thematic Network Analysis supported by NVivo software (QSR International).

Results: The Analysis identified a global theme of increased self-awareness and engagement in pain management. Three organizing themes emerged: (1) social support as a catalyst for adherence; (2) mindfulness as a strategy for emotional and sensory regulation; and (3) environmental and motivational barriers to sustained practice. Participants reported qualitative improvements in emotional regulation, sleep quality, and pain perception. Challenges included distraction due to the shared clinic setting and difficulties maintaining routine mindfulness practice, especially among participants reporting lower initial motivation.

Conclusions: The Mindfulness-Based Orofacial Pain Education Program was perceived as a feasible and beneficial adjunct to standard TMD care, promoting self-efficacy, emotional resilience, and pain self-management in a socially vulnerable population. Despite the small sample, consistent thematic convergence and participant engagement suggest promising applicability.

引言:跨性别者受到颞下颌疾病(TMDs)的影响不成比例,往往与社会心理压力和获得肯定医疗保健的机会有限相结合。传统的TMD治疗在解决慢性口面部疼痛的情绪和行为因素方面可能不足,强调需要综合干预。本研究旨在探讨以正念为基础的口腔面部疼痛教育计划作为跨性别TMD患者的补充方法的实施和感知影响。方法:采用定性设计,采用每周指导员报告和干预后焦点小组的跨性别参与者(24-39岁),每个参与者根据DC/TMD标准诊断为TMD。在八周的时间里,参与者每周参加60分钟的课程,包括正念练习、疼痛教育和自我管理策略。数据来源包括8次每周教师音频报告(n = 32录音)和一次焦点小组访谈(持续时间:68分钟)。使用NVivo软件(QSR International)支持的专题网络分析对所有转录进行分析。结果:分析确定了增加自我意识和参与疼痛管理的全球主题。出现了三个组织主题:(1)社会支持作为依从性的催化剂;(2)正念作为情绪和感觉调节策略;(3)持续实践的环境和动机障碍。参与者报告在情绪调节、睡眠质量和疼痛感知方面有了质的改善。挑战包括由于共享诊所环境造成的注意力分散,以及难以维持常规的正念练习,特别是在报告初始动机较低的参与者中。结论:基于正念的口腔面部疼痛教育项目被认为是标准TMD护理的一种可行且有益的辅助方法,可以提高社会弱势群体的自我效能感、情绪恢复力和疼痛自我管理。尽管样本小,但一致的主题趋同和参与者参与表明有希望的适用性。
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引用次数: 0
Hearing of Edentulous Patients With a Single Implant-Retained Removable Complete Overdenture: A Case Series. 无牙患者单种植保留可移动覆盖义齿的听力:一个病例系列。
IF 1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2026-01-01 DOI: 10.1111/scd.70138
Lujain Jadaan, Samer Mohsen, Ammar Almustafa

Introduction: Many studies reported on the existence of a relationship between tooth loss and hearing loss. However, only few studied the new relationship between dental implants and hearing loss.

Aims: To report the effect of a single implant-retained removable complete overdenture in the mandibular jaw on hearing loss of completely edentulous first-time denture wearers with sensorineural hearing loss.

Methods: This study is a case series that reports on the hearing thresholds of four completely edentulous patients at the ages between 55 and 62 years, which were tested before the insertion of a removable complete denture (RCD) and after loading the implant, through pure tone audiometry (PTA) for air and bone conduction in the Audiology Department at Almouwasat Hospital, from 2022 to 2024.

Results: Improvements of 5-10 dB in bone conduction thresholds were observed in some of the frequencies. A transition from minimal hearing loss to normal hearing was noted in the right ear of the second patient.

Conclusion: This experiment supports the new insight into the enhancement in hearing after loading the implant-retained removable complete overdentures, which suggests that placing dental implants improves hearing ability.

Clinical trial registration: Cases in this case series are part of a clinical trial approved by ClinicalTrials.gov Protocol Registration and Results System (PRS) with the approval number NCT05744830.

许多研究报道了牙齿脱落和听力损失之间存在的关系。然而,关于种植牙与听力损失之间的新关系的研究却很少。目的:报道下颌单种植可摘全覆盖义齿对感觉神经性听力损失患者首次全无牙义齿佩戴者听力损失的影响。方法:本研究是一个病例系列,报告了4名年龄在55岁至62岁之间的完全无牙患者,在2022年至2024年期间,在Almouwasat医院听力学部通过纯音听力学(PTA)测量空气和骨传导,在插入可摘全口义齿(RCD)之前和加载种植体之后的听力阈值。结果:部分频率骨传导阈值提高5 ~ 10 dB。第二例患者的右耳从轻微听力损失过渡到正常听力。结论:本实验支持了植入种植体可摘覆盖义齿后听力增强的新认识,提示种植体可改善听力。临床试验注册:本病例系列中的病例是ClinicalTrials.gov方案注册和结果系统(PRS)批准的临床试验的一部分,批准号为NCT05744830。
{"title":"Hearing of Edentulous Patients With a Single Implant-Retained Removable Complete Overdenture: A Case Series.","authors":"Lujain Jadaan, Samer Mohsen, Ammar Almustafa","doi":"10.1111/scd.70138","DOIUrl":"https://doi.org/10.1111/scd.70138","url":null,"abstract":"<p><strong>Introduction: </strong>Many studies reported on the existence of a relationship between tooth loss and hearing loss. However, only few studied the new relationship between dental implants and hearing loss.</p><p><strong>Aims: </strong>To report the effect of a single implant-retained removable complete overdenture in the mandibular jaw on hearing loss of completely edentulous first-time denture wearers with sensorineural hearing loss.</p><p><strong>Methods: </strong>This study is a case series that reports on the hearing thresholds of four completely edentulous patients at the ages between 55 and 62 years, which were tested before the insertion of a removable complete denture (RCD) and after loading the implant, through pure tone audiometry (PTA) for air and bone conduction in the Audiology Department at Almouwasat Hospital, from 2022 to 2024.</p><p><strong>Results: </strong>Improvements of 5-10 dB in bone conduction thresholds were observed in some of the frequencies. A transition from minimal hearing loss to normal hearing was noted in the right ear of the second patient.</p><p><strong>Conclusion: </strong>This experiment supports the new insight into the enhancement in hearing after loading the implant-retained removable complete overdentures, which suggests that placing dental implants improves hearing ability.</p><p><strong>Clinical trial registration: </strong>Cases in this case series are part of a clinical trial approved by ClinicalTrials.gov Protocol Registration and Results System (PRS) with the approval number NCT05744830.</p>","PeriodicalId":47470,"journal":{"name":"Special Care in Dentistry","volume":"46 1","pages":"e70138"},"PeriodicalIF":1.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145953336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perinatal and Neonatal Factors Affecting the Chronology of Primary Dentition in High-Risk NICU Graduates: A Cross-Sectional Study. 围生期和新生儿因素影响高危新生儿重症监护病房毕业生原发性牙列年代学:一项横断面研究。
IF 1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-11-01 DOI: 10.1111/scd.70127
Kanupriya Rathore, Sushil K Choudhary, Neeraj Gupta, Arun Singh, Rajendra Singh Dangi

Objectives: Tooth eruption may serve as a potential indicator of systemic health and a potent developmental milestone in children. This study evaluated the impact of perinatal and neonatal risk factors on the chronology of primary tooth eruption among high-risk infants admitted to the neonatal intensive care unit (NICU).

Methods and results: A cross-sectional study was conducted on 232 high-risk infants. Maternal and neonatal data were extracted from validated medical records. Oral examinations were performed to record the timing of erupted primary teeth. Delayed eruption scoring was based on deviations from established mean eruption ages ( ± 2 SD). Logistic regression was used to assess associations between risk factors and delayed tooth eruption (DTE). The mean age of first primary tooth eruption was 6.9 ± 2.6 months. The overall prevalence of delayed primary tooth eruption was 9.1%. Emergence of the first primary tooth was observed earlier in preterm infants ( < 37 weeks) (p = 0.001). Infants born to mothers with PIH (pregnancy-induced hypertension) had earlier first deciduous tooth eruption compared to those without PIH (p = 0.009).

Conclusion: The study advocates for early risk assessment and early dental referrals. Furthermore, the study identified associations between gestational age, maternal PIH, and timing of tooth eruption, underscoring the importance of early oral assessment in high-risk infants.

目的:牙萌可以作为一个潜在的指标,全身性的健康和一个强有力的发展里程碑在儿童。本研究评估围产期和新生儿危险因素对新生儿重症监护病房(NICU)高危婴儿乳牙萌出年表的影响。方法与结果:对232例高危儿进行横断面研究。从经过验证的医疗记录中提取孕产妇和新生儿数据。进行口腔检查,记录乳牙出牙的时间。延迟喷发评分基于与确定的平均喷发年龄的偏差(±2 SD)。Logistic回归用于评估危险因素与延迟牙萌(DTE)之间的关系。首次乳牙萌出的平均年龄为6.9±2.6个月。延迟乳牙萌出的总体患病率为9.1%。结论:该研究提倡早期风险评估和早期牙科转诊。此外,该研究确定了胎龄、母体PIH和出牙时间之间的关联,强调了对高危婴儿进行早期口腔评估的重要性。
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引用次数: 0
What Do the Parents of Children With Disabilities Look for in a Dedicated Orthodontic Clinic: A Grounded-Theory Study. 残疾儿童的父母在专门的正畸诊所寻找什么:一项基于理论的研究。
IF 1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-11-01 DOI: 10.1111/scd.70114
Julia Huber, Valbona Soumas, Gregory S Antonarakis

Aims: The present qualitative study aims to explore the needs of families with children with disabilities, regarding their orthodontic care in a dedicated university orthodontic clinic.

Methods: Thirteen parents of children with disabilities, followed in a University orthodontic clinic dedicated to individuals with disabilities, were selected to participate in the present study. A grounded-theory approach was used to conduct informal in-depth interviews, which were digitally recorded and transcribed verbatim. Interview transcriptions were analyzed to develop a theoretical proposition grounded in real-world observations.

Results: A core category was identified, namely the aspiration of parents of children with disabilites to afford a positive experience for their child. In association with the core category, six other categories emerged: location, accessibility, and a welcoming environment; convenience and availability; an empathetic team; good communication; appropriate and modern equipment; and quality of treatment outcome.

Conclusions: The families of children with disabilities seek personalized and high-quality orthodontic care in a favorable environment with a welcoming, empathetic, and communicative team. Gaining a clearer understanding of what families value in clinics and teams that provide orthodontic care for children with disabilties can help inform meaningful and positive improvements to these dedicated services.

目的:本定性研究旨在探讨残疾儿童家庭在大学正畸诊所接受正畸护理的需求。方法:选择13名残疾儿童的父母,在一所专门为残疾儿童服务的大学正畸诊所进行随访。采用扎根理论的方法进行非正式的深入访谈,并对访谈进行数字记录和逐字转录。对访谈记录进行分析,以建立一个基于现实世界观察的理论命题。结果:确定了一个核心类别,即残疾儿童的父母希望为他们的孩子提供积极的体验。与核心类别相关的其他六个类别出现了:位置、可达性和温馨的环境;便利性和可获得性;有同理心的团队;良好的沟通;适当和现代化的设备;以及治疗结果的质量。结论:残疾儿童家庭在良好的环境中寻求个性化和高质量的正畸护理,并拥有一个热情、共情和沟通的团队。更清楚地了解家庭在为残疾儿童提供正畸护理的诊所和团队中的价值,有助于为这些专门服务提供有意义和积极的改进。
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引用次数: 0
Prophylactic Antibiotics for Prevention of Infective Endocarditis or Bacteremia in Pediatric Patients With Congenital Heart Disease Undergoing Dental Procedures: Systematic Review. 预防性抗生素预防接受牙科手术的先天性心脏病患儿感染性心内膜炎或菌血症:系统综述。
IF 1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-11-01 DOI: 10.1111/scd.70112
Cameron Loper, Jordan Baskette, Timothy R Fagan, Divesh Sardana

Aim: To assess the effectiveness of prophylactic antibiotics in preventing infective endocarditis (IE) after dental procedures in pediatric patients with congenital heart disease.

Methods: Six electronic databases and grey literature were searched for randomized controlled trials (RCTs), case-control studies, and cohort studies in pediatric patients who received antibiotic prophylaxis (AP) before any dental procedure compared to pediatric patients undergoing the same procedures without AP to prevent IE and/or bacteremia. The Newcastle-Ottawa scale was used to evaluate the internal validity of the included studies. The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) was used to assess the certainty of evidence.

Results: 1774 studies were screened after duplicate removal. Three case-control studies met the inclusion criteria and were included. One study evaluated IE as an outcome, whereas the other two studies evaluated bacteremia after dental procedures. Meta-analysis could not be conducted for IE, whereas pooling results were attempted for two studies evaluating bacteremia as an outcome. The odds of IE after a dental procedure within the last 6 months with AP were higher than without AP (Odds ratio: 3.44, 95% CI: 0.93, 12.65, p = 0.06) in the only study. However, AP was effectively able to reduce bacteremia after dental procedures in two studies that evaluated bacteremia (Pooled odds ratio: 0.24, 95% CI: 0.14, 0.42, p < 0.05).

Conclusions: The GRADE evidence was very low to conclude that prophylactic antibiotics might have a role in preventing IE or bacteremia in children with congenital cardiac diseases due to insufficient studies.

目的:评价预防性抗生素在预防先天性心脏病患儿牙科手术后感染性心内膜炎(IE)的有效性。方法:检索6个电子数据库和灰色文献,检索随机对照试验(rct)、病例对照研究和队列研究,这些研究将在任何牙科手术前接受抗生素预防(AP)的儿科患者与接受相同手术但未使用抗生素预防IE和/或菌血症的儿科患者进行比较。纽卡斯尔-渥太华量表用于评估纳入研究的内部效度。建议评估、发展和评价分级(GRADE)用于评估证据的确定性。结果:重复去除后筛选了1774项研究。三个病例对照研究符合纳入标准并被纳入。一项研究评估IE作为结果,而另外两项研究评估牙科手术后的菌血症。不能对IE进行荟萃分析,而对两项评估菌血症作为结局的研究进行了汇总分析。在唯一的一项研究中,有AP的患者在过去6个月内牙科手术后发生IE的几率高于没有AP的患者(优势比:3.44,95% CI: 0.93, 12.65, p = 0.06)。然而,在两项评估菌血症的研究中,AP能够有效地减少牙科手术后的菌血症(合并优势比:0.24,95% CI: 0.14, 0.42, p)。结论:由于研究不足,GRADE证据非常低,无法得出预防性抗生素可能在预防先天性心脏病儿童IE或菌血症方面发挥作用的结论。
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引用次数: 0
Comment on: "Anemia During Pregnancy and Molar Incisor Hypomineralization in Children and Teenagers: Systematic Review and Meta-Analysis". 评论:“妊娠期贫血与儿童和青少年磨牙门牙低矿化:系统回顾和荟萃分析”。
IF 1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-11-01 DOI: 10.1111/scd.70130
Mengting Zhang
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引用次数: 0
Reply to the Letter Regarding Bridging the Gap in Orofacial Pain Assessment for Individuals with Intellectual Disabilities: A Systematic Review of Validated Tools. 回复关于弥合智力残疾患者口面部疼痛评估差距的信函:对有效工具的系统回顾。
IF 1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-11-01 DOI: 10.1111/scd.70117
Bruna de Oliveira Rech, Ana Carolina Costa Borges, Jefferson R Tenório, Beatriz Dulcineia Mendes Souza, Alessandra Rodrigues de Camargo
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引用次数: 0
期刊
Special Care in Dentistry
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