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Efficacy of Midazolam in Outpatient Pediatric Dentistry: A Systematic Review. 咪达唑仑在门诊儿科牙科的疗效:一项系统评价。
IF 1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-01 DOI: 10.1111/scd.70107
Judit Rabassa-Blanco, Pau Cahuana-Bartra, Yndira González-Chópite, Maria Dolores Rocha-Eiroa, Albert Ramírez-Rámiz, Elias Isaack Mashala, Lluís Brunet-Llobet, Jaume Miranda-Rius

Aims: The aim of this systematic review was to analyze the efficacy, advantages and adverse effects of midazolam in outpatient pediatric dentistry.

Methods: This review was carried out in accordance with the PRISMA criteria. A systematic electronic search was conducted through MEDLINE/PubMed, Scopus, and the Cochrane Library databases up to September 2024. An advanced and reproducible search strategy was used to identify relevant studies. Articles were excluded if they focused solely on midazolam as a premedication for general anesthesia or elective surgery, involving patients with special diseases. Inclusion criteria required participants aged 0-16 years, patients with behavioral and/or cooperation disorders and undergoing simple dental restorative procedures under local anesthesia, such as fillings, pulp therapies, stainless steel crowns, or basic extractions. Patients with specific medical conditions, as well as those who were not monitored for vital signs during sedation, were excluded from the study. The risk of bias assessment was analyzed using the criteria set out in the Cochrane Handbook for Systematic Reviews of Interventions, version 5.1.0.

Results: A total of 28 studies were included in the analysis, which were conducted across 11 countries and involved a total of 4374 children aged between 2 and 14 years. Most studies demonstrated a low risk of bias. Many of the participants were ASA I or II status and were assessed using behavioral scales, primarily the Frankl scale. Twelve adjunct drugs were combined with midazolam, and various administration routes were explored, including oral, intranasal, and buccal. Dosing protocols varied, as did fasting guidelines prior to sedation. Outcome measures included vital sign monitoring and behavioral assessments, most commonly via the Houpt and MOAA/S scales. Midazolam generally proved effective in reducing anxiety and improving cooperation, with reported benefits extending to future dental visits. Adverse effects were infrequently noted and typically mild, including nausea, vomiting, and paradoxical reactions.

Conclusions: Midazolam has been shown to be an effective and safe agent for moderate sedation in pediatric dental procedures when administered orally at a dose range of 0.3-0.5 mg/kg. The evidence suggests that it reliably reduces anxiety and improves cooperation. Supervision, preferably by an anesthesiologist, is recommended when combined with other drugs to ensure patient safety.

目的:本系统综述的目的是分析咪达唑仑在门诊儿科牙科的疗效、优点和不良反应。方法:本综述按照PRISMA标准进行。系统的电子检索通过MEDLINE/PubMed、Scopus和Cochrane图书馆数据库进行,截止到2024年9月。采用先进的可重复搜索策略来识别相关研究。如果文章只关注咪达唑仑作为全身麻醉或选择性手术的前用药,并且涉及特殊疾病的患者,则文章被排除。纳入标准要求参与者年龄在0-16岁之间,患有行为和/或合作障碍的患者,并且在局部麻醉下进行简单的牙齿修复手术,如填充,牙髓治疗,不锈钢冠或基本拔牙。有特殊医疗条件的患者,以及那些在镇静期间没有监测生命体征的患者,被排除在研究之外。偏倚风险评估采用Cochrane干预措施系统评价手册5.1.0版中的标准进行分析。结果:共有28项研究纳入分析,这些研究在11个国家进行,涉及4374名年龄在2至14岁之间的儿童。大多数研究显示偏倚风险较低。许多参与者为ASA I或II级,并使用行为量表进行评估,主要是Frankl量表。12种辅助药物联合咪达唑仑,探索口服、鼻内、口腔等给药途径。给药方案各不相同,镇静前的禁食指南也是如此。结果测量包括生命体征监测和行为评估,最常见的是通过Houpt和MOAA/S量表。咪达唑仑通常被证明在减少焦虑和改善合作方面是有效的,据报道,其益处延伸到未来的牙科就诊。不良反应很少被注意到,通常是轻微的,包括恶心、呕吐和矛盾反应。结论:咪达唑仑已被证明是儿童牙科手术中有效和安全的中度镇静药物,口服剂量范围为0.3-0.5 mg/kg。有证据表明,它确实能减少焦虑,提高合作。当与其他药物联合使用时,建议由麻醉师进行监督,以确保患者安全。
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引用次数: 0
Bridging the Gap in Orofacial Pain Assessment for Individuals With Intellectual Disabilities: A Systematic Review of Validated Tools. 弥合智力残疾患者口面部疼痛评估的差距:对有效工具的系统回顾。
IF 1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-01 DOI: 10.1111/scd.70097
Bruna de Oliveira Rech, Ana Carolina Costa Borges, Jefferson R Tenório, Beatriz Dulcineia Mendes Souza, Alessandra Rodrigues de Camargo

Aims: Systematically review the literature to answer the focused question: "What is the best way to facilitate pain communication for patients with intellectual disabilities (ID) in dental care?"

Methods: A systematic search strategy was conducted in five databases and gray literature. Studies evaluating pain communication in dental care for patients with ID were included. The risk of bias was assessed according to the Meta-Analysis of Statistics Assessment and Review Instrument.

Results: A total of 1525 studies were screened, and after applying exclusion criteria, 10 articles remained. The included studies were published between 2003 and 2021, with sample sizes ranging from 28 to 270 participants with developmental disabilities. The Dental Discomfort Questionnaire (DDQ) was the most commonly used tool in the studies. Most studies showed a low risk of bias.

Conclusion: The DDQ is the most validated tool for assessing dental pain in individuals with ID, though evidence in adults is limited. Other tools provide useful behavioral cues but may not clearly differentiate pain from discomfort or anxiety. The absence of a gold standard underscores the need for context-appropriate tool selection and clinician training to interpret nonverbal pain, enhancing diagnostic accuracy and promoting equitable care.

目的:系统回顾文献,回答“在牙科护理中促进智力障碍患者疼痛沟通的最佳方法是什么?”方法:系统检索5个数据库和灰色文献。纳入了评估ID患者牙科护理中疼痛沟通的研究。偏倚风险采用Meta-Analysis of Statistics Assessment and Review Instrument进行评估。结果:共筛选1525项研究,应用排除标准后,仍有10篇文章。纳入的研究发表于2003年至2021年之间,样本量从28到270名发育障碍参与者不等。牙齿不适问卷(DDQ)是研究中最常用的工具。大多数研究显示偏倚风险较低。结论:DDQ是评估ID患者牙痛最有效的工具,尽管在成人中的证据有限。其他工具提供有用的行为线索,但可能无法清楚区分疼痛、不适或焦虑。金标准的缺乏强调了需要根据具体情况选择合适的工具和培训临床医生来解释非语言疼痛,提高诊断准确性和促进公平护理。
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引用次数: 0
Special Needs Dentistry CBCE Extension at Long-Term Care Facilities: Insights of Oro-Systemic Care and Entry Workforce Training. 长期护理机构的特殊需要牙科CBCE扩展:oro -系统护理和入门劳动力培训的见解。
IF 1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-01 DOI: 10.1111/scd.70103
Yonsu Kim, Maryam Tabrizi, Jae-In Ryu, Dong-Hun Han, Jong Ho Won, Iulia Ioaniatoaia-Chaudhry, Rumy Lee, Ji Won Yoo
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引用次数: 0
The 4P Strategy for Managing Hypersensitive Gag Reflex: A Case Report and Clinical Guide. 处理超敏感呕吐反射的4P策略:一个病例报告和临床指南。
IF 1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-01 DOI: 10.1111/scd.70104
Panupol Kunasarapun, Aisyah Binti Ahmad Fisal, Hussain IbnAhmad, Caoimhin Mac Giolla Phadraig
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引用次数: 0
Frequency and Severity of Post-Procedure Bleeding Events Following Dental Extractions Completed in Patients on Heparin Therapy. 肝素治疗患者拔牙后出血事件的发生频率和严重程度。
IF 1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-01 DOI: 10.1111/scd.70109
Claudia Patricia Lopez Silva, Brandon Lim, Pritam Daniel Sundaresan, Ying Gu, Mathew Albert Wei Ting Lim

Introduction: Despite the existence of clear management protocols for patients treated with warfarin, direct-acting oral anticoagulants, and anti-thrombotic medications requiring dental extractions, guidelines for patients on injectable anticoagulants or heparins are limited. This absence of advice for dentists and doctors results in potential confusion about the safety of these dental procedures, impacting timely patient care.

Methods: A prospective, observational study was completed at two Australian hospital-based dental clinics to determine the frequency and severity of bleeding events, within the 48-h period, following dental extractions completed in heparinized patients.

Results: During the study period, 95 heparinized patients received a total of 185 dental extractions. Six patients had minor bleeding in the first 48 h after their procedure, representing a rate of 6.3%. All bleeding episodes were managed with direct pressure to the site with gauze. Bivariate analysis identified that patients treated with unfractionated heparin, compared to low-molecular-weight heparins, and extractions completed closer to the last dose of heparin had higher rates of post-extraction bleeding (p ≤ 0.01).

Conclusions: Dental extractions can be completed safely for patients on injectable anticoagulants when careful local hemostatic measures are used. Based on the low rates and minor nature of post-extraction bleeding, interruption or change to dosing of heparin therapy is unnecessary to facilitate these invasive dental procedures.

尽管对于使用华法林、直接作用口服抗凝剂和需要拔牙的抗血栓药物治疗的患者有明确的管理方案,但对于注射抗凝剂或肝素治疗的患者的指南是有限的。缺乏对牙医和医生的建议会导致对这些牙科手术安全性的潜在混淆,影响对患者的及时护理。方法:在澳大利亚两家医院牙科诊所完成了一项前瞻性观察性研究,以确定肝素化患者拔牙后48小时内出血事件的频率和严重程度。结果:研究期间,95例肝素化患者共拔牙185次。6例患者在手术后48小时内出现轻微出血,发生率为6.3%。所有出血都是用纱布直接压在伤口上处理的。双变量分析发现,与低分子量肝素相比,使用未分离肝素治疗的患者,在离最后一次肝素剂量更近的时间完成提取,提取后出血的发生率更高(p≤0.01)。结论:使用注射抗凝药物的患者,在采取严密的局部止血措施的情况下,可以安全完成拔牙。由于拔牙后出血发生率低且发生率低,因此无需中断或改变肝素治疗剂量以促进这些侵入性牙科手术。
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引用次数: 0
Tooth Grinding in Older Adults: A Retrospective Cross-Sectional Study. 老年人磨牙:一项回顾性横断面研究。
IF 1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-01 DOI: 10.1111/scd.70092
Leonardo Marchini, Jhanvi Desai, Fang Qian

Objectives: This study aims to determine the prevalence of self-reported tooth grinding among older adult patients at a dental school and to examine the associations between tooth grinding and various demographic and clinical factors.

Methods: Data were retrieved from the electronic patient database at the University of Iowa College of Dentistry. Descriptive statistics and bivariate analyses were used to explore associations between tooth grinding and various demographic and clinical factors. Multivariable logistic regression was used to identify factors that were significantly associated with tooth grinding.

Results: Out of 12,550 adults aged 65 years or older, 1598 (12.7%) who responded to the tooth grinding question were included in the analysis, with 853 (53.4%) reporting tooth grinding. Multivariable logistic regression analysis revealed that gender and drug addiction were significantly associated with tooth grinding, with males and those with a history of drug addiction having higher odds.

Conclusions: In this large sample of older adults, self-reported tooth grinding had a high prevalence, with males and those with a history of drug addiction having significantly higher odds of experiencing it.

目的:本研究旨在确定在牙科学校的老年患者中自我报告的磨牙率,并检查磨牙与各种人口统计学和临床因素之间的关系。方法:数据从爱荷华大学牙科学院电子患者数据库中检索。使用描述性统计和双变量分析来探讨磨牙与各种人口统计学和临床因素之间的关系。使用多变量逻辑回归来确定与磨牙显著相关的因素。结果:在12550名65岁及以上的成年人中,1598名(12.7%)回答了磨牙问题,其中853名(53.4%)报告了磨牙。多变量logistic回归分析显示,性别和药物成瘾与磨牙有显著相关性,男性和有药物成瘾史者的相关性更高。结论:在这个较大的老年人样本中,自我报告的磨牙患病率很高,男性和有药物成瘾史的人经历磨牙的几率明显更高。
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引用次数: 0
Does Virtual Reality Reduce Dental Treatment Stress in Patients With Dental Anxiety? A Comparison With Nitrous Oxide Sedation: A Crossover Study. 虚拟现实能减轻牙科焦虑症患者的治疗压力吗?与氧化亚氮镇静的比较:一项交叉研究。
IF 1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-01 DOI: 10.1111/scd.70100
Hitoshi Ishitani, Yuto Tanaka, Kayo Koyanagi, Keita Yoshida, Yoshihiro Momota, Yoshiaki Ono

Aims: This study aimed to compare the effects of virtual reality (VR) and nitrous oxide (N2O) sedation on anxiety and stress in patients with dental anxiety.

Methods and results: Eight patients with dental anxiety (five women; mean age, 41 years) with scores ≥ 19 on the Japanese version of the Modified Dental Anxiety Scale underwent three interventions: VR (natural landscapes and ambient music), N2O (30% N2O/70% oxygen), and no intervention (control). Autonomic nervous activity, including low frequency (LF), high frequency (HF), and the LF/HF ratio, was measured. VR significantly reduced LF and LF/HF levels compared to those of the control (p < 0.05), suggesting lower sympathetic nervous system activity, whereas N2O had no effect (p = 0.88, 0.46, respectively). VR and N2O increased HF levels compared to those of the control (p < 0.05), reflecting enhanced parasympathetic activity. Subjective anxiety was lower for VR and N2O interventions (p < 0.05). VR immersion ratings indicated that most participants experienced moderate-to-high immersion levels.

Conclusion: VR is an effective, noninvasive option for managing dental anxiety, suggesting greater reductions in sympathetic-related markers than those of control and, in some analyses, N2O, in this small crossover sample. Its accessibility and lack of pharmacological side effects support its integration into patient-centered care, particularly for mild-to-moderate dental anxiety.

目的:本研究旨在比较虚拟现实(VR)和氧化亚氮(N2O)镇静对牙科焦虑症患者焦虑和压力的影响。方法与结果:8例日版改良牙科焦虑量表评分≥19分的牙科焦虑患者(女性5名,平均年龄41岁),分别进行了VR(自然景观和环境音乐)、N2O (30% N2O/70%氧气)和不干预(对照组)三种干预。测量自主神经活动,包括低频(LF)、高频(HF)和LF/HF比值。与对照组相比,VR显著降低了LF和LF/HF水平(p < 0.05),表明交感神经系统活性降低,而N2O无影响(p分别为0.88、0.46)。与对照组相比,VR和N2O增加了HF水平(p < 0.05),反映了副交感神经活动的增强。主观焦虑在VR和N2O干预组较低(p < 0.05)。虚拟现实沉浸度评分表明,大多数参与者都经历了中等到高度的沉浸度。结论:在这个小的交叉样本中,VR是一种有效的、无创的治疗牙科焦虑的选择,表明与对照组相比,交感神经相关标志物的减少更大,在一些分析中,N2O的减少更大。它的可及性和缺乏药理学副作用支持其融入以患者为中心的护理,特别是对轻至中度牙科焦虑。
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引用次数: 0
QR-iHemoTrack: An Integrated Hemocare Digital Framework for Management of Hemophilia Patients. qr - ihemtrack:血友病患者管理的综合血液护理数字框架。
IF 1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-01 DOI: 10.1111/scd.70110
Priyadharshini Ragavane, Priyanga Chandrasekaran, Angeline Hephzibah Pauljoseph, Senthil Murugappan
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引用次数: 0
Teledentistry for Older Community-Dwelling Patients: A Scope Review of Concordance Between Virtual and Clinical Examination. 老年社区居民的远程牙科:虚拟检查与临床检查一致性的范围回顾。
IF 1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-01 DOI: 10.1111/scd.70101
Monira Samaan Kallás, Daniela Torres Wardil Krause, Christopher A Childs, Leonardo Marchini, Alexandre Leopold Busse
<p><p>Teledentistry, which integrates telecommunications and digital imaging, offers a versatile solution for addressing the oral health needs of the growing global older adult population. This approach enhances access to care, mitigates geographical barriers, and optimizes costs, proving particularly beneficial for institutionalized older adults. Studies assessing the accuracy of virtual versus in-person examinations in this population have reported positive outcomes, reinforcing the feasibility of remote consultations, diagnoses, and treatment planning. However, studies specifically focusing on community-dwelling older adults remains absent from the literature. This study aims to examine the dental literature regarding the accuracy, concordance, and effectiveness of virtual examinations in comparison to in-person assessments for screening and diagnosing of oral diseases in community-dwelling older adults. A scoping review was conducted using the PICo strategy. A health sciences librarian performed a comprehensive search across six databases (MEDLINE, EMBASE, CINAHL, Cochrane, Scopus, and Web of Science) using Mesh keywords. Article selection involved a three-stage process: screening titles/abstracts, reading full texts, and final selection based on pre-defined inclusion and exclusion criteria. Two researchers independently selected articles using Rayyan for blind review, and their disagreements was solved by a third-reviewer researcher, with more experience. A total of 11 187 articles were initially identified across all included databases. Of these, 3719 duplicates were detected and removed. The remaining 7468 articles were imported into the Rayyan platform, where an additional 311 duplicate records were identified and manually excluded by the reviewers. After this step, 7154 articles were excluded for not meeting the predefined inclusion criteria. As a result of the screening and eligibility process, three articles remained, of which only one was ultimately included in the final analysis. This single study evaluated the accuracy of diagnosing dental caries in geriatric patients attending an outpatient clinic using smartphone intraoral photographs compared to a standard clinical examination. The study identified a strong concordance between virtual and in-person examinations, demonstrating an acceptable level of diagnostic accuracy for caries detection in older adults using smartphone-based assessments. Despite a comprehensive search, the identification of only a single article on concordance among community-dwelling older adults highlights the scarcity of literature on this topic. There is a significant research gap in the integration of teledentistry and radiographic examinations for this population. Community-dwelling older adults possess distinct characteristics that necessitate focused attention. Subgingival proximal root caries, a prevalent dental condition in this group, relies heavily on radiographic assessment for accurate diagnosis.
远程牙科综合了电信和数字成像技术,为满足日益增长的全球老年人口的口腔健康需求提供了一种通用的解决方案。这种方法增加了获得护理的机会,减轻了地理障碍,并优化了成本,证明对住院的老年人特别有益。在这一人群中评估虚拟检查与面对面检查的准确性的研究报告了积极的结果,加强了远程咨询、诊断和治疗计划的可行性。然而,文献中仍然缺乏专门针对社区居住老年人的研究。本研究的目的是检查牙科文献中关于虚拟检查的准确性、一致性和有效性,并将其与面对面评估进行比较,以筛查和诊断社区居住的老年人口腔疾病。使用PICo策略进行了范围审查。一位健康科学图书管理员使用Mesh关键字对六个数据库(MEDLINE、EMBASE、CINAHL、Cochrane、Scopus和Web of Science)进行了全面搜索。文章选择包括三个阶段的过程:筛选标题/摘要,阅读全文,根据预先定义的纳入和排除标准进行最终选择。两位研究者独立选择使用Rayyan进行盲评的文章,他们的分歧由一位经验更丰富的第三审稿研究者解决。在所有纳入的数据库中,最初总共确定了11 187篇文章。其中,检测到并删除了3719个重复。其余7468篇文章被导入Rayyan平台,审稿人在该平台上识别并手动排除了另外311条重复记录。在这一步之后,7154篇文章因不符合预定义的纳入标准而被排除。经过筛选和资格程序,剩下三篇文章,其中只有一篇最终列入最后分析。这项研究评估了在门诊就诊的老年患者中,使用智能手机口内照片与标准临床检查相比诊断龋齿的准确性。该研究确定了虚拟检查和现场检查之间的强烈一致性,表明使用基于智能手机的评估对老年人进行龋齿检测的诊断准确性达到了可接受的水平。尽管进行了全面的搜索,但只有一篇关于社区居住老年人的一致性的文章的识别突出了这一主题的文献的稀缺性。在这一人群的远程牙科和放射检查的整合方面存在重大的研究差距。居住在社区的老年人具有明显的特点,需要集中注意。龈下近根龋是本组常见的牙病,其准确诊断在很大程度上依赖于影像学评估。本综述发现,对于生活在社区中的老年人,关于虚拟与面对面临床评估的准确性的文献明显缺乏,只有一项研究可用。进一步的研究势在必行,以制定和完善适合这一特定人群需求的适当数字评估方案。
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引用次数: 0
The Impact of Family-Centered Care on Oral Health for Children With Special Health Care Needs. 以家庭为中心的护理对有特殊保健需要儿童口腔健康的影响。
IF 1 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-09-01 DOI: 10.1111/scd.70095
Bedant Chakraborty, Fernando A Wilson, Nizar K Wehbi, Li-Wu Chen, Hyo Jung Tak

Aim: To examine the association of family-centered care (FCC) with oral health indicators among children with special health care needs (CSHCN).

Methods: Data includes the CSHCN population from the 2017 to 2019 National Survey of Children's Health (NSCH). Four parent- and caregiver-reported binary oral health outcomes were assessed: preventive dental visits (PDVs), cavities, condition of teeth, and oral health problems. The primary independent variable was parent- and caregiver-perceived FCC. Multivariable logistic models were used to investigate the association of FCC with oral health indicators.

Results: Of 16 338 CSHCNs, a high proportion (83.29%) received FCC. Receipt of FCC was positively associated with better oral health outcomes among CSHCN. Compared to those who did not receive FCC, CSHCN who received FCC had 56% higher odds of having one or more PDV (adjusted odds ratio: 1.56, 95% Confidence Interval: 1.15-2.10), were 1.90 times more likely to have teeth rated as excellent or very good, had 82% greater odds of having no cavities, and 1.91 times higher odds of having no reported oral health problems.

Conclusions: FCC plays a critical role in maintaining oral health among CSHCNs. Its broader implementation is a potential solution to reduce disparities in oral health among CSHCN and across the pediatric population.

目的:探讨有特殊保健需要儿童(CSHCN)的家庭中心护理(FCC)与口腔健康指标的关系。方法:数据包括2017 - 2019年全国儿童健康调查(NSCH)的CSHCN人口。评估了四种父母和照顾者报告的二元口腔健康结果:预防性牙科就诊(pdv)、蛀牙、牙齿状况和口腔健康问题。主要的自变量是父母和照顾者感知的FCC。采用多变量logistic模型探讨FCC与口腔健康指标的关系。结果:16 338例CSHCNs接受FCC治疗的比例较高(83.29%)。在CSHCN中,接受FCC与更好的口腔健康结果呈正相关。与未接受FCC的患者相比,接受FCC的CSHCN患一种或多种PDV的几率高出56%(调整优势比:1.56,95%可信区间:1.15-2.10),牙齿被评为优秀或非常好的可能性高出1.90倍,没有蛀牙的几率高出82%,没有报告口腔健康问题的几率高出1.91倍。结论:FCC在维持CSHCNs口腔健康中起关键作用。它的广泛实施是一个潜在的解决方案,以减少CSHCN和整个儿科人群在口腔健康方面的差距。
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引用次数: 0
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Special Care in Dentistry
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