Aids Education and Prevention最新文献

We examined correlates of condom use among heterosexual whites, blacks, and Hispanics (ages 20-45 years) with an human immunodeficiency virus (HIV) risk factor in a community-based longitudinal sample (San Francisco; n = 716). Lag models were used to examine hypothesized antecedents of condom use at wave 2. High levels of condom use were associated with labeling one's sexual behavior as risky for HIV infection, high levels of condom enjoyment and commitment to use condoms, good sexual communication practices, gender (trend), and marital status. The results support the need for wide-ranging intervention programs that stimulate people to make personal risk assessments, teach basic sexual skills, and direct those in need of intensive help to appropriate agencies.

To explore the attitudes of a multi-ethnic sample (African-American, Caucasian, Latino) of parents, a telephone survey was conducted with 297 parents whose children attend school in New York City (98 African-Americans, 100 Latinos, and 99 Caucasians). The survey interview assessed a wide range of issues related to AIDS and AIDS education. In a series of logistic regressions that controlled for education, we compared each ethnic group (African-Americans, Latinos) with Caucasians as the reference. The majority of parents indicated that they supported AIDS education efforts in the schools, but there was considerable mistrust of the government and health professionals, particularly among the African-American parents. African-American and Latino parents were more likely to perceive AIDS as a threat and believe that AIDS education is more effective for Caucasians. We discuss implications for AIDS prevention and recommend strategies to overcome barriers to AIDS education and prevention in multi-ethnic communities.

Transgender youth in the U.S. have unique health needs but often face barriers to accessing and receiving health care services, which contribute to disparate health outcomes including high risk for HIV acquisition. This article reports on a pilot randomized clinical trial of MyPEEPS Mobile for young transgender men (YTM) versus delayed intervention on condomless receptive anal and vaginal acts at 3 and 6 months after baseline. Participants rated the app as highly usable. Retention rates at 3 and 6 months were 89%. There were lower rates of condomless anal or vaginal sex acts during the intervention periods, but this reduction was not significantly different versus nonintervention periods. There was a higher likelihood of nPEP and PrEP use and HIV/STI testing during intervention periods, but this increase was not significantly different than nonintervention periods. Findings from the study support the feasibility of MyPEEPS Mobile for HIV prevention in YTM.

This study examines the impact of a nurse-led sexual and reproductive health (SRH) intervention on the knowledge and attitudes of adolescents living with HIV (ALHIV). Using a randomized controlled trial design, 50 participants (25 control, 25 intervention) were recruited, with 47 completing the study between October 2023 and April 2024. The intervention group received four interactive sessions covering personal hygiene, contraceptive use, STI prevention, and risky behaviors. Baseline assessments showed no significant difference between groups (t =-1.411, p = .300). However, post-intervention analysis revealed a significant improvement in SRH knowledge and attitudes in the intervention group (t = 5.467, p < .001). Participants also showed increased comfort discussing SRH with nurses (χ² = 22.17, p < .001), greater willingness to disclose HIV status (χ² = 7.69, p = .021), and better understanding of STI testing importance (χ² = 18.694, p < .001). These findings support integrating nurse-led SRH programs into adolescent HIV care to improve outcomes.

This paper discusses negative experiences with using condoms reported by the condom user subsample of (n = 975) of a household probability sample of low income, urban, African-American and Hispanic youth. Condom users were asked about 12 specific experiences with condoms. Although the pattern of the association varied with the particular belief and experience, it appeared that, overall, having had a negative experience increased the likelihood that the user would agree with a negative belief about condoms (p ≤ .005). In addition, users who had experienced a condom making it hard to move in and out of the vagina or anus were less likely both to intend to use a condom and to have used a condom at last intercourse (p ≤ .005). Condom use was also less likely if the user had experienced condoms interrupting lovemaking or reducing feeling or sensation.

Despite the proven effectiveness of human immunodeficiency virus (HIV) pre-exposure prophylaxis (PrEP), its use remains low in high-incidence areas. This study examined knowledge and barriers to PrEP among individuals at risk in Southern California. From September 2022 to April 2023, we recruited adult men who have sex with men, residing in San Bernardino and Riverside counties, who were not living with HIV and not using PrEP. Recruitment occurred through targeted online advertisements and clinic-distributed materials. Statistical analyses explored associations between demographic factors and barriers to PrEP. While 81% had heard of PrEP, nearly half were unaware of HIV testing requirements or of its availability for uninsured individuals. Uninsured participants were significantly less comfortable discussing sexual health with providers (OR: 0.19, 95% CI [0.05, 0.68]). Addressing misinformation, reducing provider stigma, and expanding access for uninsured individuals are essential for increasing PrEP use.

We aimed to describe long-term use trajectories and predictors prior to recreational cannabis legalization in people with HIV in Ontario, Canada. We analysed interview data from the prospective Ontario HIV Treatment Network Cohort Study from 2008 to 2017. We conducted Latent Class Growth Analyses to describe cannabis use trajectories and chi-square tests to identify trajectory group predictors. Most participants (N = 3,299) were male (81%), gay (57%), current/former tobacco smokers (58%), and many had significant symptoms of depression (43%). Four cannabis use trajectory groups were identified (Low/No Use (67%); Increased Use (4%); Decreased use (2%); High Use (26%)). Relative to the Low/No Use group, membership in the High Use group was associated with several predictors such as being older age, completing university, smoking tobacco, and significant depressive symptoms. Future research should explore the relationship between cannabis use and depressive symptoms, outcomes associated with trajectory groups and changes in use trajectories following recreational legalization.

In the field of HIV prevention and care, most studies of HIV syndemic problems are cross-sectional, few differentiate by HIV transmission groups, and few focus on people living with HIV (PWH). We analyzed one-year longitudinal data of 692 sexually active PWH (heterosexual men [HM], heterosexual women [HW], and men who have sex with men [MSM]) in care from Brazil, Thailand, and Zambia. Syndemic scores (0-3+) included stimulant use, polydrug use, depression, alcohol use, and fear of discrimination. Overall, syndemic scores were associated with lower ART adherence over time, but this differed across sexual transmission categories. For HM and HW, those with 2 or 3+ syndemic problems had lower odds of ART adherence than those with none. However, for MSM, the association between syndemic scores and ART adherence was not significant. While syndemic problems generally predicted suboptimal ART adherence among PWH, the association appears nuanced across subgroups.

This mixed-methods study explored willingness to use long-acting injectable pre-exposure prophylaxis (LAI-PrEP) among a pharmacy-based sample of men, including sexual and gender minoritized (SGM) individuals. We conducted qualitative interviews (n = 10) with HIV-negative Black men, including Black SGM individuals, and surveys (n = 103) across three study phases with men recruited from community pharmacies in Atlanta, Georgia. Interviews explored perceived benefits and concerns related to LAI-PrEP; surveys assessed willingness and related reasons. Thematic analysis was used for interview transcripts, and descriptive statistics summarized survey responses. Participants mentioned benefits such as improved adherence and reduced stigma, but also noted concerns about medical mistrust and fear of needles. Willingness was higher in the transitional pilot phase than in the pilot phase, where concerns about side effects and comfort were more common. Findings highlight the need for tailored LAI-PrEP strategies that address barriers among Black SGM populations and promote equitable HIV prevention.

Disparate rates of HIV infection among Black MSM and TGW emphasize the need for interventions designed to overcome obstacles to increasing PrEP adoption within these populations. This study compared PrEP-use groups on a variety of attitudinal and behavioral factors related to PrEP adoption. Regression analysis confirmed that current and former users demonstrated greater PrEP knowledge and communicated more frequently to friends about PrEP and its benefits than nonusers. Former users exhibited more positive attitudes and perceived less stigma regarding PrEP use than other groups. Current users reported the highest prevalence of condomless anal sex and multiple partners; conversely, former users were most often in stable monogamous relationships. Our findings are consistent with the notion of prevention-effective adherence and advance our understanding of attitudinal supports for that paradigm. This research also suggests that recruitment of former PrEP users could increase the pool of effective peer behavior-change agents in future intervention efforts.