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An Algorithm to Evaluate Methodological Rigor and Risk of Bias in Single-Case Studies. 单例研究中评估方法严谨性和偏倚风险的算法。
IF 2.3 3区 心理学 Q3 PSYCHOLOGY, CLINICAL Pub Date : 2023-11-01 Epub Date: 2019-08-30 DOI: 10.1177/0145445519863035
Michael Perdices, Robyn L Tate, Ulrike Rosenkoetter

Critical appraisal scales play an important role in evaluating methodological rigor (MR) of between-groups and single-case designs (SCDs). For intervention research this forms an essential basis for ascertaining the strength of evidence. Yet, few such scales provide classifications that take into account the differential weighting of items contributing to internal validity. This study aimed to develop an algorithm derived from the Risk of Bias in N-of-1 Trials (RoBiNT) Scale to classify MR and risk of bias magnitude in SCDs. The algorithm was applied to 46 SCD experiments. Two experiments (4%) were classified as Very High MR, 14 (30%) as High, 5 (11%) as Moderate, 2 (4%) as Fair, 2 (4%) as Low, and 21 (46%) as Very Low. These proportions were comparable to the What Works Clearinghouse classifications: 13 (28%) met standards, 8 (17%) met standards with reservations, and 25 (54%) did not meet standards. There was strong association between the two classification systems.

临界评估量表在评估组间和单病例设计(SCD)的方法严谨性(MR)方面发挥着重要作用。对于干预研究来说,这是确定证据强度的重要基础。然而,很少有这样的量表提供考虑到对内部有效性有贡献的项目的不同权重的分类。本研究旨在开发一种源自1次试验中N次偏倚风险量表(RoBiNT)的算法,对SCD中的MR和偏倚程度风险进行分类。该算法已应用于46个SCD实验。两个实验(4%)被归类为甚高MR,14个(30%)被归类于高MR,5个(11%)被分类为中等MR,2个(4%)为一般MR,2(4%)归类于低MR,21个(46%)归类于甚低MR。这些比例与What Works Clearinghouse的分类相当:13个(28%)符合标准,8个(17%)符合保留标准,25个(54%)不符合标准。这两个分类系统之间有很强的联系。
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引用次数: 20
Consistency in Single-Case ABAB Phase Designs: A Systematic Review. 单一案例ABAB阶段设计的一致性:系统综述。
IF 2.3 3区 心理学 Q3 PSYCHOLOGY, CLINICAL Pub Date : 2023-11-01 Epub Date: 2019-06-19 DOI: 10.1177/0145445519853793
René Tanious, Tamal Kumar De, Bart Michiels, Wim Van den Noortgate, Patrick Onghena

The current article presents a systematic review of consistency in single-case ABAB phase designs. We applied the CONsistency of DAta Patterns (CONDAP) measure to a sample of 460 data sets retrieved from 119 applied studies published over the past 50 years. The main purpose was to (a) identify typical CONDAP values found in published ABAB designs and (b) develop interpretational guidelines for CONDAP to be used for future studies to assess the consistency of data patterns from similar phases. The overall distribution of CONDAP values is right-skewed with several extreme values to the right of the center of the distribution. The B-phase CONDAP values fall within a narrower range than the A-phase CONDAP values. Based on the cumulative distribution of CONDAP values, we offer the following interpretational guidelines in terms of consistency: very high, 0 ≤ CONDAP ≤ 0.5; high, 0.5 < CONDAP ≤ 1; medium, 1 < CONDAP < 1.5; low, 1.5 < CONDAP ≤ 2; very low, CONDAP > 2. We give examples of combining CONDAP benchmarks with visual analysis of single-case ABAB phase designs and conclude that the majority of data patterns (41.2%) in published ABAB phase designs is medium consistent.

本文对单一案例ABAB阶段设计的一致性进行了系统综述。我们将DAta模式的一致性(CONDAP)测量应用于从过去50年发表的119项应用研究中检索的460个数据集的样本。主要目的是(a)确定已发表的ABAB设计中发现的典型CONDAP值,以及(b)为CONDAP制定解释指南,用于未来的研究,以评估类似阶段数据模式的一致性。CONDAP值的总体分布是右偏的,分布中心右侧有几个极值。B相的CONDAP值落在比a相的CONDAP值更窄的范围内。基于CONDAP值的累积分布,我们在一致性方面提供了以下解释指南:非常高,0≤CONDAP≤0.5;高,0.52。我们给出了将CONDAP基准与单一案例ABAB阶段设计的可视化分析相结合的例子,并得出结论,在已发表的ABAB阶段的设计中,大多数数据模式(41.2%)是中等一致的。
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引用次数: 10
Rethinking Research on Prediction and Prevention of Psychotherapy Dropout: A Mechanism-Oriented Approach. 心理治疗退出预测与预防研究的反思:一种机制导向的方法。
IF 2.3 3区 心理学 Q3 PSYCHOLOGY, CLINICAL Pub Date : 2023-11-01 Epub Date: 2018-08-05 DOI: 10.1177/0145445518792251
Andrew A Cooper, Alexander C Kline, Allison L Baier, Norah C Feeny
Dropout is a ubiquitous psychotherapy outcome in clinical practice and treatment research alike, yet it remains a poorly understood problem. Contemporary dropout research is dominated by models of prediction that lack a strong theoretical foundation, often drawing on data from clinical trials that report on dropout in an inconsistent and incomplete fashion. In this article, we assert that dropout is a critical treatment outcome that is worthy of investigation as a mechanistic process. After briefly describing the scope of the dropout problem, we discuss the many factors that limit the field’s present understanding of dropout. We then articulate and illustrate a transdiagnostic conceptual framework for examining psychotherapy dropout in contemporary research, concluding with recommendations for future research. With a more comprehensive understanding of the factors affecting retention, research efforts can shift toward investigating key processes underlying treatment dropout, thus, boosting prediction and informing strategies to mitigate dropout in clinical practice.
辍学是临床实践和治疗研究中普遍存在的心理治疗结果,但它仍然是一个鲜为人知的问题。当代的辍学研究主要是缺乏强大理论基础的预测模型,通常借鉴临床试验的数据,这些数据以不一致和不完整的方式报告辍学情况。在这篇文章中,我们断言辍学是一个重要的治疗结果,值得作为一个机制过程进行研究。在简要描述了辍学问题的范围后,我们讨论了限制该领域目前对辍学的理解的许多因素。然后,我们阐明并说明了一个跨诊断的概念框架,用于检查当代研究中的心理治疗辍学,并为未来的研究提出建议。随着对影响保留率的因素有了更全面的了解,研究工作可以转向调查导致治疗失败的关键过程,从而在临床实践中加强预测和告知策略,以减轻失败。
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引用次数: 19
An Exploration of Intervention Augmentation in a Single Case. 单例介入增强的探索。
IF 2.3 3区 心理学 Q3 PSYCHOLOGY, CLINICAL Pub Date : 2023-11-01 Epub Date: 2018-08-23 DOI: 10.1177/0145445518796202
James F Boswell, Carly M Schwartzman

Recent work has highlighted that process-outcome relationships are likely to vary depending on the client, yet much work remains to be done in the area of tailoring interventions to a given client. This naturalistic single-case analysis provides an example of augmenting a treatment protocol with "off protocol" relaxation methods, based on routinely collected outcome information to guide shared decision making. Intensive case study analyses were applied to one client with principal generalized anxiety disorder and comorbid major depressive disorder receiving transdiagnostic cognitive-behavioral therapy. The client completed two routine anxiety and depression symptom and functioning scales prior to each session of naturalistic treatment. Time series analyses were applied to the two symptom measures. Among the results, (a) significant linear decreases in anxiety and depression from baseline to posttreatment were observed; and (b) the introduction of relaxation methods had a significant impact on the course of anxiety symptom change. In conclusion, routine outcome assessment can be used to inform intervention augmentation with individual clients. Furthermore, regular assessment is needed to determine if a client may benefit from an alternative set of specific intervention strategies.

最近的工作强调,过程-结果关系可能因客户而异,但在为特定客户量身定制干预措施方面仍有许多工作要做。这种自然主义的单一病例分析提供了一个例子,根据常规收集的结果信息,用“非协议”放松方法来增强治疗方案,以指导共同决策。对一名接受跨诊断认知行为治疗的主要广泛性焦虑症和合并症重度抑郁障碍患者进行了深入的病例分析。在每次自然治疗之前,客户完成了两个常规的焦虑和抑郁症状和功能量表。将时间序列分析应用于两种症状测量。在这些结果中,(a)从基线到治疗后,观察到焦虑和抑郁显著线性下降;(b)放松方法的引入对焦虑症状的变化过程有显著影响。总之,常规结果评估可用于告知个别客户的干预强化。此外,还需要定期评估,以确定客户是否可以从一套替代的具体干预策略中受益。
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引用次数: 2
An Examination of Measurement Procedures and Characteristics of Baseline Outcome Data in Single-Case Research. 单例研究中基线结果数据的测量程序和特征的检查。
IF 2.3 3区 心理学 Q3 PSYCHOLOGY, CLINICAL Pub Date : 2023-11-01 Epub Date: 2019-08-02 DOI: 10.1177/0145445519864264
James E Pustejovsky, Daniel M Swan, Kyle W English

There has been growing interest in using statistical methods to analyze data and estimate effect size indices from studies that use single-case designs (SCDs), as a complement to traditional visual inspection methods. The validity of a statistical method rests on whether its assumptions are plausible representations of the process by which the data were collected, yet there is evidence that some assumptions-particularly regarding normality of error distributions-may be inappropriate for single-case data. To develop more appropriate modeling assumptions and statistical methods, researchers must attend to the features of real SCD data. In this study, we examine several features of SCDs with behavioral outcome measures in order to inform development of statistical methods. Drawing on a corpus of over 300 studies, including approximately 1,800 cases, from seven systematic reviews that cover a range of interventions and outcome constructs, we report the distribution of study designs, distribution of outcome measurement procedures, and features of baseline outcome data distributions for the most common types of measurements used in single-case research. We discuss implications for the development of more realistic assumptions regarding outcome distributions in SCD studies, as well as the design of Monte Carlo simulation studies evaluating the performance of statistical analysis techniques for SCD data.

作为传统目测方法的补充,人们对使用统计方法分析数据和估计单例设计(SCDs)研究的效应大小指数越来越感兴趣。统计方法的有效性取决于其假设是否合理地表示了收集数据的过程,然而有证据表明,一些假设——特别是关于误差分布的正态性——可能不适合单一情况的数据。为了开发更合适的建模假设和统计方法,研究人员必须注意实际SCD数据的特征。在这项研究中,我们通过行为结果测量来研究scd的几个特征,以便为统计方法的发展提供信息。根据涵盖一系列干预措施和结果构建的七个系统综述的300多项研究的语料库,包括大约1800例病例,我们报告了研究设计的分布、结果测量程序的分布以及单例研究中使用的最常见测量类型的基线结果数据分布的特征。我们讨论了关于SCD研究结果分布的更现实假设的发展的影响,以及评估SCD数据统计分析技术性能的蒙特卡罗模拟研究的设计。
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引用次数: 16
Transition States in Single Case Experimental Designs. 单例实验设计中的过渡态。
IF 2.3 3区 心理学 Q3 PSYCHOLOGY, CLINICAL Pub Date : 2023-11-01 Epub Date: 2019-04-09 DOI: 10.1177/0145445519839213
Kristen M Brogan, John T Rapp, Bailey R Sturdivant

The continuation of a baseline pattern of responding into a treatment phase, sometimes referred to as a "transition state," can obscure interpretation of data depicted in single-case experimental designs (SCEDs). For example, when using visual analysis, transition states may lead to the conclusion that the treatment is ineffective. Likewise, the inclusion of overlapping data points in some statistical analyses may lead to conclusions that the treatment had a small effect size and give rise to publication bias. This study reviewed 20 volumes in a journal that publishes primarily SCEDs studies. We defined a transition state as a situation wherein at least the first three consecutive data points of a treatment phase or condition are within the range of the baseline phase or condition. Results indicate that transitions states (a) were present for 7.4% of graphs that met inclusion criteria and (b) occurred for a mean of 4.9 data points before leading to behavior change. We discuss some implications and directions for future research on transition states.

持续的基线反应模式进入治疗阶段,有时被称为“过渡状态”,可能会模糊对单例实验设计(SCED)中描述的数据的解释。例如,当使用视觉分析时,过渡状态可能会导致治疗无效的结论。同样,在一些统计分析中包含重叠的数据点可能会得出这样的结论,即治疗的效果很小,并导致发表偏差。这项研究综述了一份主要发表SCED研究的期刊上的20卷。我们将过渡状态定义为治疗阶段或条件的至少前三个连续数据点在基线阶段或条件范围内的情况。结果表明,在导致行为改变之前,7.4%的图存在过渡状态(a),平均4.9个数据点出现过渡状态(b)。我们讨论了对未来过渡态研究的一些启示和方向。
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引用次数: 12
Meta-Analysis of Single-Case Experimental Design using Multilevel Modeling. 使用多级建模的单一案例实验设计的元分析。
IF 2.3 3区 心理学 Q3 PSYCHOLOGY, CLINICAL Pub Date : 2023-11-01 Epub Date: 2023-01-16 DOI: 10.1177/01454455221144034
Eunkyeng Baek, Wen Luo, Kwok Hap Lam

Multilevel modeling (MLM) is an approach for meta-analyzing single-case experimental designs (SCED). In this paper, we provide a step-by-step guideline for using the MLM to meta-analyze SCED time-series data. The MLM approach is first presented using a basic three-level model, then gradually extended to represent more realistic situations of SCED data, such as modeling a time variable, moderators representing different design types and multiple outcomes, and heterogeneous within-case variance. The presented approach is then illustrated using real SCED data. Practical recommendations using the MLM approach are also provided for applied researchers based on the current methodological literature. Available free and commercial software programs to meta-analyze SCED data are also introduced, along with several hands-on software codes for applied researchers to implement their own studies. Potential advantages and limitations of using the MLM approach to meta-analyzing SCED are discussed.

多级建模(MLM)是一种对单例实验设计(SCED)进行元分析的方法。在本文中,我们提供了一个使用MLM对SCED时间序列数据进行元分析的分步指南。MLM方法首先使用基本的三级模型提出,然后逐渐扩展以表示SCED数据的更现实的情况,例如对时间变量建模,表示不同设计类型和多个结果的调节因子,以及异构的案例内方差。然后使用实际SCED数据对所提出的方法进行了说明。根据当前的方法学文献,还为应用研究人员提供了使用传销方法的实用建议。还介绍了可用于元分析SCED数据的免费和商业软件程序,以及应用研究人员实施自己研究的几个动手软件代码。讨论了使用MLM方法进行SCED元分析的潜在优势和局限性。
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引用次数: 0
Using AB Designs With Nonoverlap Effect Size Measures to Support Clinical Decision-Making: A Monte Carlo Validation. 使用具有非重叠效应大小度量的AB设计来支持临床决策:蒙特卡罗验证。
IF 2.3 3区 心理学 Q3 PSYCHOLOGY, CLINICAL Pub Date : 2023-11-01 Epub Date: 2019-07-13 DOI: 10.1177/0145445519860219
Antonia R Giannakakos, Marc J Lanovaz

Single-case experimental designs often require extended baselines or the withdrawal of treatment, which may not be feasible or ethical in some practical settings. The quasi-experimental AB design is a potential alternative, but more research is needed on its validity. The purpose of our study was to examine the validity of using nonoverlap measures of effect size to detect changes in AB designs using simulated data. In our analyses, we determined thresholds for three effect size measures beyond which the type I error rate would remain below 0.05 and then examined whether using these thresholds would provide sufficient power. Overall, our analyses show that some effect size measures may provide adequate control over type I error rate and sufficient power when analyzing data from AB designs. In sum, our results suggest that practitioners may use quasi-experimental AB designs in combination with effect size to rigorously assess progress in practice.

单例实验设计通常需要延长基线或停止治疗,这在某些实际环境中可能不可行或不符合伦理。准实验AB设计是一种潜在的替代方案,但其有效性还需要更多的研究。我们研究的目的是检验使用效应大小的非重叠测量来检测AB设计中使用模拟数据的变化的有效性。在我们的分析中,我们确定了三种效应大小测量的阈值,超过这些阈值,I型错误率将保持在0.05以下,然后检查使用这些阈值是否能提供足够的功率。总体而言,我们的分析表明,在分析AB设计的数据时,一些效应大小度量可以提供对I型错误率的充分控制和足够的功率。总之,我们的研究结果表明,从业者可以使用准实验AB设计,结合效果大小来严格评估实践中的进展。
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引用次数: 5
Single-Case Data Analysis: A Practitioner Guide for Accurate and Reliable Decisions. 单一案例数据分析:准确可靠决策的从业者指南。
IF 2.3 3区 心理学 Q3 PSYCHOLOGY, CLINICAL Pub Date : 2023-11-01 Epub Date: 2019-08-23 DOI: 10.1177/0145445519867054
Jennifer Ninci

Practitioners frequently use single-case data for decision-making related to behavioral programming and progress monitoring. Visual analysis is an important and primary tool for reporting results of graphed single-case data because it provides immediate, contextualized information. Criticisms exist concerning the objectivity and reliability of the visual analysis process. When practitioners are equipped with knowledge about single-case designs, including threats and safeguards to internal validity, they can make technically accurate conclusions and reliable data-based decisions with relative ease. This paper summarizes single-case experimental design and considerations for professionals to improve the accuracy and reliability of judgments made from single-case data. This paper can also help practitioners to appropriately incorporate single-case research design applications in their practice.

从业者经常使用单个案例数据来进行与行为规划和进度监控相关的决策。可视化分析是报告图表化单个病例数据结果的重要和主要工具,因为它提供了即时的、情境化的信息。对视觉分析过程的客观性和可靠性存在批评。当从业者具备关于单一案例设计的知识,包括对内部有效性的威胁和保障时,他们可以相对轻松地做出技术上准确的结论和可靠的基于数据的决策。本文总结了单例实验设计和专业人员提高单例数据判断准确性和可靠性的注意事项。本文还可以帮助从业者在实践中适当地结合单个案例研究设计应用。
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引用次数: 16
Innovations in Technology and Mechanisms of Change in Behavioral Interventions. 行为干预的技术创新和变革机制。
IF 2.3 3区 心理学 Q3 PSYCHOLOGY, CLINICAL Pub Date : 2023-11-01 Epub Date: 2019-04-29 DOI: 10.1177/0145445519845603
Nicole R Nugent, Sachin R Pendse, Heather T Schatten, Michael F Armey

The purpose of this manuscript is to provide an overview of, and rationale for, the increasing adoption of a wide range of cutting-edge technological methods in assessment and intervention which are relevant for treatment. First, we review traditional approaches to measuring and monitoring affect, behavior, and cognition in behavior and cognitive-behavioral therapy. Second, we describe evolving active and passive technology-enabled approaches to behavior assessment including emerging applications of digital phenotyping facilitated through fitness trackers, smartwatches, and social media. Third, we describe ways that these emerging technologies may be used for intervention, focusing on novel applications for the use of technology in intervention efforts. Importantly, though some of the methods and approaches we describe here warrant future testing, many aspects of technology can already be easily incorporated within an established treatment framework.

这份手稿的目的是概述在评估和干预中越来越多地采用与治疗相关的尖端技术方法,并为其提供理由。首先,我们回顾了在行为和认知行为治疗中测量和监测情感、行为和认知的传统方法。其次,我们描述了不断发展的主动和被动技术支持的行为评估方法,包括通过健身追踪器、智能手表和社交媒体促进的数字表型的新兴应用。第三,我们描述了这些新兴技术用于干预的方式,重点介绍了在干预工作中使用技术的新应用。重要的是,尽管我们在这里描述的一些方法和方法值得未来测试,但技术的许多方面已经可以很容易地纳入既定的治疗框架中。
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引用次数: 12
期刊
Behavior Modification
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