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Tracheobronchial calcification: an incidental finding in a patient on long-term Warfarin treatment. 气管支气管钙化:一名长期接受华法林治疗患者的偶然发现。
IF 0.9 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-24 eCollection Date: 2024-01-01 DOI: 10.11604/pamj.2024.48.127.41936
Aishwarya Kishor Kedar, Vivek Dipakrao Alone
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引用次数: 0
A comparative study of food safety knowledge among mobile food vendors and canteen food handlers in markets in Kano Metropolis, Northwest Nigeria. 尼日利亚西北部卡诺市市场中流动食品摊贩和食堂食品经营者的食品安全知识比较研究。
IF 0.9 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-24 eCollection Date: 2024-01-01 DOI: 10.11604/pamj.2024.48.131.36934
Usman Muhammad Ibrahim, Zahrau Zubairu, Surayya Murtala Sunusi, Suraj Musa Inuwa, Ado Shehu, Sagir Magaji, Aliyu Ahmed Sadiq, Shamsuddeen Abdullahi, Yusuf Karkarna Mustapha, Sunday Audu, Jamilu Aliyu Bawa, Abba Ahmed Danzomo, Usman Bashir, Abubakar Mohammed Jibo, Muhammad Lawan Umar

Introduction: foodborne diseases are an emerging public health challenge due to the global increase in vended food. This study aimed to compare food safety knowledge among mobile and canteen food handlers in Kano metropolis.

Methods: a comparative cross-sectional design was used to study 310 mobile food vendors and 310 canteen food handlers selected using a multi-stage sampling technique. Data were collected by interviewer-administered questionnaire and analyzed at univariate, bivariate, and multivariate levels using SPSS version 20 at 5% α level of significance.

Results: the mean ages (±SD) of mobile and canteen food vendors were 24.6±9.1 and 32.1±10.3 years, respectively. Majority of them were females (66.2% mobile and 61.5% canteen food vendors). Good knowledge of food safety and hygiene was found among 22 (7.2%) and 67 (23.3%), mobile and canteen food vendors, respectively. Mobile food vendors who worked for less than 35 hours per week were 70% less likely to have good knowledge of food safety [AOR=0.3, 95%CI=0.2-0.6, p<0.001] relative to those who worked for ≥35 hours per week. Among canteen food vendors, marital status [AOR=1.7, 95%CI=1.2-1.3, p=0.002], hours of food vending per week [AOR=2.7, 95%CI=1.6-4.3, p<0.001], and job description [AOR=0.5, 95%CI=0.3-0.9, p=0.008], were independent predictors of food safety knowledge.

Conclusion: knowledge of food safety and hygiene was found to be suboptimal among both canteen food vendors and mobile food vendors. The government should ensure regular training and supervision of food vendors for compliance with food safety guidelines.

导言:由于全球销售食品的增加,食源性疾病成为新出现的公共卫生挑战。本研究旨在对卡诺市流动食品摊贩和食堂食品从业人员的食品安全知识进行比较。研究方法:本研究采用比较横断面设计,通过多阶段抽样技术选取了 310 名流动食品摊贩和 310 名食堂食品从业人员。结果:流动食品摊贩和食堂食品经营者的平均年龄(±SD)分别为 24.6±9.1 岁和 32.1±10.3 岁。女性占大多数(流动食品摊贩占 66.2%,食堂食品摊贩占 61.5%)。流动食品摊贩和食堂食品摊贩中分别有 22 人(7.2%)和 67 人(23.3%)具备良好的食品安全和卫生知识。每周工作时间少于 35 小时的流动食品摊贩拥有良好食品安全知识的可能性比其他摊贩低 70%[AOR=0.3,95%CI=0.2-0.6,p]。政府应确保对食品摊贩进行定期培训和监督,使其遵守食品安全准则。
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引用次数: 0
Prevalence and factors associated with uncontrolled type 2 diabetes among patients in Kirehe District, Rwanda: a cross-sectional study. 卢旺达基雷赫地区未受控制的 2 型糖尿病患者的患病率及其相关因素:一项横断面研究。
IF 0.9 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-24 eCollection Date: 2024-01-01 DOI: 10.11604/pamj.2024.48.128.43864
Symaque Dusabeyezu, Jean Nepomuscene Renzaho, Nasiru Sani

Introduction: the increase in type 2 diabetes mellitus (T2DM) is a major public health issue on a global scale. A continuous rise in blood sugar levels, even if there are no symptoms of diabetes, leads to tissue degeneration and, in certain cases, fatal diseases.

Methods: in this cross-sectional study, the researcher examined the prevalence of uncontrolled type 2 diabetes mellitus among patients in Kirehe District Health Facilities from October 2023 to February 2024. The target population was 333 patients and the sample size was 201 patients who visited the non-communicable disease clinics throughout the time of data collection, those with T2DM diagnosis for at least a year, and non-pregnant women.

Results: the mean age was 57.23 years with an 11.06 standard deviation. Females represented 58.7% (n=118) while males were 41.3% (n=83). The prevalence of uncontrolled type 2 diabetes mellitus was 72.6% (n=146). Patients who had ever been lost to follow-up were more likely to have uncontrolled T2DM (AOR=3.24, 95% CI: 1.06-5.90, p=0.036) compared to those who regularly visited the health facility for care and follow-up. Patients who had comorbidities to diabetes were more likely to have uncontrolled T2DM (AOR=2.48, 95% CI: 1.31-4.68, p=0.005) compared to those who did not have comorbidities.

Conclusion: the prevalence of uncontrolled T2DM is high; healthcare providers have a responsibility to perform home visits to reduce the lost to follow-up rate and to conduct regular screening sessions for diabetes comorbidities.

导言:2 型糖尿病(T2DM)的增加是全球范围内的一个重大公共卫生问题。即使没有糖尿病症状,血糖水平的持续升高也会导致组织变性,在某些情况下还会引发致命疾病。方法:在这项横断面研究中,研究人员调查了 2023 年 10 月至 2024 年 2 月期间基雷赫区卫生机构患者中未得到控制的 2 型糖尿病的患病率。目标人群为 333 名患者,样本量为 201 名在整个数据收集期间在非传染性疾病诊所就诊的患者、诊断为 T2DM 至少一年的患者以及非孕妇。结果:平均年龄为 57.23 岁,标准差为 11.06。女性占 58.7%(118 人),男性占 41.3%(83 人)。未控制的 2 型糖尿病患者占 72.6%(146 人)。与定期到医疗机构接受护理和随访的患者相比,曾经失去随访的患者更有可能患有未控制的二型糖尿病(AOR=3.24,95% CI:1.06-5.90,p=0.036)。结论:未得到控制的 T2DM 患病率很高;医疗服务提供者有责任进行家访,以降低失去随访的比率,并对糖尿病合并症进行定期筛查。
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引用次数: 0
Postnatal care utilization and associated factors among women who gave birth within the last 12 months in northwest Ethiopia: a cross-sectional study. 埃塞俄比亚西北部过去 12 个月内分娩妇女的产后护理利用率及相关因素:一项横断面研究。
IF 0.9 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-24 eCollection Date: 2024-01-01 DOI: 10.11604/pamj.2024.48.126.42397
Tesfahun Hailemariam, Asmamaw Atnafu, Lemma Derseh Gezie, Teshale Belayneh, Binyam Tilahun

Introduction: postnatal care after birth is a crucial component in saving the lives of mothers and new-borns. A paucity of evidence indicated that women's unwillingness to receive care after birth remains a challenge in resource-limited settings in general and in Ethiopia in particular. This study aimed to assess the level of postnatal care utilization and factors affecting it in northwest Ethiopia.

Methods: a community-based cross-sectional study was conducted from October to November 2020. A total of 811 women who had given birth within the last year were involved in the study. Both random and fixed effects were reported using an adjusted odds ratio with a 95% confidence interval and a p-value of <0.05.

Results: the study revealed that postnatal care utilization was 19.85% (95% CI: 20.8-29.4) in northwest Ethiopia. Maternal education of secondary and above (AOR =2.65; 95% CI: 1.43, 4.94); facility delivery (AOR = 3.99; 95% CI: 2.44, 6.55); membership in women associations in the community (AOR = 1.6; 95% CI: 1.07, 2.4); four or more ANC contacts (AOR = 1.51; 95% CI: 1.03, 2.22); having health education at health post level (AOR = 1.77; 95% CI: 1.21, 2.58), and birth order (AOR = 2.64; 95% CI: 1.21, 5.78) were significantly associated with postnatal care utilization.

Conclusion: postnatal care utilization is low in rural northwest Ethiopia compared to findings from most resource-limited settings. The existing health system should consider community-based intervention strategies focusing on maternal health education, healthcare accessibility, and promoting women's participation in the community to be more effective in improving postnatal care utilization.

导言:产后护理是挽救母亲和新生儿生命的重要组成部分。大量证据表明,在资源有限的环境中,尤其是在埃塞俄比亚,妇女不愿接受产后护理仍是一项挑战。本研究旨在评估埃塞俄比亚西北部地区的产后护理利用率及其影响因素。方法:2020 年 10 月至 11 月期间,开展了一项基于社区的横断面研究。共有 811 名去年分娩的妇女参与了研究。随机效应和固定效应均使用调整后的几率进行报告,其置信区间为 95%,P 值为 结果:研究显示,埃塞俄比亚西北部的产后护理利用率为 19.85%(95% CI:20.8-29.4)。产妇教育程度为中学及以上(AOR =2.65;95% CI:1.43,4.94);设施分娩(AOR =3.99;95% CI:2.44,6.55);社区妇女协会会员(AOR =1.6;95% CI:1.07,2.4);四次或四次以上产前护理接触(AOR =1.51;95% CI:1.03,2.22);在卫生站接受过健康教育(AOR = 1.结论:与大多数资源有限地区的调查结果相比,埃塞俄比亚西北部农村地区的产后护理利用率较低。现有的卫生系统应考虑采取以社区为基础的干预策略,重点关注孕产妇健康教育、医疗保健的可及性以及促进妇女参与社区活动,以更有效地提高产后护理利用率。
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引用次数: 0
Healthcare use and sexually transmitted infections treatment-seeking: a mixed methods cross-sectional survey among hard-to-reach fishing communities of Lake Victoria, Uganda. 医疗保健的使用和性传播感染的就医情况:在乌干达维多利亚湖难以接触到的渔业社区进行的混合方法横断面调查。
IF 0.9 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-24 eCollection Date: 2024-01-01 DOI: 10.11604/pamj.2024.48.134.27244
Ali Ssetaala, Sabrina Welsh, Teddy Nakaweesa, Mathias Wambuzi, Gertrude Nanyonjo, Annet Nanvubya, Juliet Mpendo, Annet Nalutaaya, Julius Ssempiira, Leslie Nielsen, Pat Fast, Matt Price, Noah Kiwanuka

Introduction: Uganda´s fishing communities experience a high burden of sexually transmitted infections (STIs) including human immunodeficiency virus (HIV), with limited access to healthcare. Knowledge on healthcare use and treatment seeking will help identify unmet needs and facilitate appropriate allocation of resources.

Methods: between 2014-2015, a mixed methods cross-sectional survey was conducted in four fishing communities on Lake Victoria, Uganda, as part of preparedness for HIV trials. The goal was to understand health problems (having any illness, medical condition, or injury in the past 12 months), perceptions of healthcare, health services use, and factors associated with seeking STI care. Data were collected from participants aged 13-49 years; quantitatively using a structured questionnaire and qualitatively via focus group discussions (FGDs) and key informant interviews (KIIs). Information covered recent health problems, health services use, and healthcare perceptions. Multivariable logistic regression modeling was used to determine factors associated with seeking care for STIs.

Results: participants´ median (interquartile range) age was 29 (23-35) years, more than half (51.9%, 763/1,469), were females, and the majority (60.4%, 888/1,469) had up to seven years of formal education. Most participants reported having had health problems (76%, 1,117/1,469). The most frequently reported health issues were STI symptoms (52.6%, 587/1,117). Lack of health services was mentioned as one of the reasons for not seeking care during the FDGs and KIIs. Adolescents, 13-19 were less likely to seek care for STIs symptoms than adults of 20 or more years (aOR= 0.5 (95% CI 0.3-0.9)). Females were more likely to seek STI treatment (aOR= 1.4 (95% CI 1.0-2.1)), as were participants who worked mainly in bars, restaurants or lodges (aOR= 2.0 (95% CI 1.1-3.6)).

Conclusion: in these communities, adolescents have low treatment seeking for STIs symptoms.

导言:乌干达渔业社区的性传播感染(STI)(包括人类免疫缺陷病毒(HIV))负担沉重,但获得医疗保健的机会有限。方法:2014-2015 年间,在乌干达维多利亚湖畔的四个渔业社区开展了一项混合方法横断面调查,作为 HIV 试验准备工作的一部分。目的是了解健康问题(过去 12 个月中是否患有任何疾病、病症或受伤)、对医疗保健的看法、医疗服务的使用情况以及寻求性传播感染护理的相关因素。数据收集对象年龄在 13-49 岁之间;定量数据采用结构化问卷,定性数据采用焦点小组讨论 (FGD) 和关键信息提供者访谈 (KII)。信息涉及近期的健康问题、医疗服务使用情况以及对医疗保健的看法。结果:参与者的年龄中位数(四分位数间距)为 29(23-35)岁,半数以上(51.9%,763/1,469)为女性,大多数人(60.4%,888/1,469)接受过最多 7 年的正规教育。大多数参与者表示曾有过健康问题(76%,1 117/1 469)。报告最多的健康问题是性传播感染症状(52.6%,587/1,117)。在家庭访问和知识问答中,缺乏医疗服务被认为是不就医的原因之一。与 20 岁或 20 岁以上的成年人相比,13-19 岁的青少年因性传播感染症状就医的可能性较低(aOR= 0.5 (95% CI 0.3-0.9))。女性更有可能寻求性传播感染治疗(aOR= 1.4 (95% CI 1.0-2.1)),主要在酒吧、餐馆或旅馆工作的参与者也更有可能寻求性传播感染治疗(aOR= 2.0 (95% CI 1.1-3.6))。
{"title":"Healthcare use and sexually transmitted infections treatment-seeking: a mixed methods cross-sectional survey among hard-to-reach fishing communities of Lake Victoria, Uganda.","authors":"Ali Ssetaala, Sabrina Welsh, Teddy Nakaweesa, Mathias Wambuzi, Gertrude Nanyonjo, Annet Nanvubya, Juliet Mpendo, Annet Nalutaaya, Julius Ssempiira, Leslie Nielsen, Pat Fast, Matt Price, Noah Kiwanuka","doi":"10.11604/pamj.2024.48.134.27244","DOIUrl":"10.11604/pamj.2024.48.134.27244","url":null,"abstract":"<p><strong>Introduction: </strong>Uganda´s fishing communities experience a high burden of sexually transmitted infections (STIs) including human immunodeficiency virus (HIV), with limited access to healthcare. Knowledge on healthcare use and treatment seeking will help identify unmet needs and facilitate appropriate allocation of resources.</p><p><strong>Methods: </strong>between 2014-2015, a mixed methods cross-sectional survey was conducted in four fishing communities on Lake Victoria, Uganda, as part of preparedness for HIV trials. The goal was to understand health problems (having any illness, medical condition, or injury in the past 12 months), perceptions of healthcare, health services use, and factors associated with seeking STI care. Data were collected from participants aged 13-49 years; quantitatively using a structured questionnaire and qualitatively via focus group discussions (FGDs) and key informant interviews (KIIs). Information covered recent health problems, health services use, and healthcare perceptions. Multivariable logistic regression modeling was used to determine factors associated with seeking care for STIs.</p><p><strong>Results: </strong>participants´ median (interquartile range) age was 29 (23-35) years, more than half (51.9%, 763/1,469), were females, and the majority (60.4%, 888/1,469) had up to seven years of formal education. Most participants reported having had health problems (76%, 1,117/1,469). The most frequently reported health issues were STI symptoms (52.6%, 587/1,117). Lack of health services was mentioned as one of the reasons for not seeking care during the FDGs and KIIs. Adolescents, 13-19 were less likely to seek care for STIs symptoms than adults of 20 or more years (aOR= 0.5 (95% CI 0.3-0.9)). Females were more likely to seek STI treatment (aOR= 1.4 (95% CI 1.0-2.1)), as were participants who worked mainly in bars, restaurants or lodges (aOR= 2.0 (95% CI 1.1-3.6)).</p><p><strong>Conclusion: </strong>in these communities, adolescents have low treatment seeking for STIs symptoms.</p>","PeriodicalId":48190,"journal":{"name":"Pan African Medical Journal","volume":"48 ","pages":"134"},"PeriodicalIF":0.9,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11567908/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142649364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Calcinosis universalis in juvenile dermatomyositis. 幼年皮肌炎普遍钙化症
IF 0.9 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-24 eCollection Date: 2024-01-01 DOI: 10.11604/pamj.2024.48.132.38591
Maryem Ferjani, Mounira El Euch
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引用次数: 0
Challenges in managing neonatal ileal atresia in limited-resource settings: a case report. 在资源有限的环境中管理新生儿回肠闭锁所面临的挑战:病例报告。
IF 0.9 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-23 eCollection Date: 2024-01-01 DOI: 10.11604/pamj.2024.48.125.44315
Frank Martin Sudai, Macrice Yakayashi, Lusajo Mwagobele, Peter Kafubhi, Habakuki Ntabudyo, Kasili Joseph Magembe, Lazaro Yohana Madeha, Stanley Zakaria Binagi, Joseph Nangawe, Jesca Paul Lebba

Neonatal ileal atresia is a form of intestinal obstruction characterized by narrowing, complete closure, or absence of a segment of the ileum. This case involves a 5-day-old female neonate presented with abdominal distension and bilious vomiting. The neonate, delivered via spontaneous vertex birth weighing 2.9 kg, showed no fever and maintained stable vital signs during examination. Physical assessment revealed abdominal distension, hyper-tympanic areas, dullness in the lower quadrants, reduced bowel sounds, and a patent anus with an empty rectum. Imaging studies confirmed intestinal obstruction from dilated small bowels, leading to explorative laparotomy identifying ileal atresia, necessitating cecostomy placement. Despite surgical intervention, the neonate experienced nutritional complications and unfortunately passed away three days postoperatively. This case underscores the complexities of early diagnosis and management in neonates with intrauterine conditions, particularly in resource-limited settings with limited access to total parenteral nutrition.

新生儿回肠闭锁是一种肠梗阻,其特点是一段回肠狭窄、完全闭锁或缺失。本病例中的新生儿是一名出生 5 天的女性,出现腹胀和胆汁性呕吐。新生儿为自然顶产,体重 2.9 千克,无发热症状,检查时生命体征平稳。体格检查显示腹胀、膻中区亢进、下腹部沉闷、肠鸣音减弱、肛门通畅但直肠空虚。影像学检查证实小肠扩张导致肠梗阻,因此进行了探查性开腹手术,发现回肠闭锁,必须进行盲肠造口术。尽管进行了手术干预,但新生儿仍出现了营养并发症,术后三天不幸去世。该病例强调了早期诊断和管理患有宫内疾病的新生儿的复杂性,尤其是在资源有限、获得全肠外营养的机会有限的情况下。
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引用次数: 0
Cross-cultural adaptation and reliability of patient asthma knowledge questionnaire in the regional Indian language Marathi: a cross-sectional study. 印度马拉地语哮喘患者知识问卷的跨文化适应性和可靠性:一项横断面研究。
IF 0.9 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-22 eCollection Date: 2024-01-01 DOI: 10.11604/pamj.2024.48.124.37870
Vishakha Sitaram Nalage, Varoon Chandramohan Jaiswal, Deepika Sohan Burman, Ramya Anand Shetty, Akanksha Amarsingh Chauhan, Amruta Devendra Acharekar

Introduction: patient education is the cornerstone of the clinical management of bronchial asthma. The patient asthma knowledge questionnaire is a valid and reliable tool to assess the disease specific knowledge in the patients with bronchial asthma. To the best of our knowledge and literature search, there is no tool available in Marathi language to assess the knowledge of bronchial asthma in patients.

Methods: standard translation guidelines for cross-cultural adaptation were followed. Forward and backward translations were performed by the eligible translators (T1 and T2) as per the guidelines. Synthesis of the translated versions was performed by translators and recording observer (T12). Recommendations by the expert committee were done to develop a pre-final version. The pre-final version was then tested on 30 individuals with bronchial asthma. The reliability of the translated version was assessed by the internal consistency and intra-class correlation coefficient.

Results: thirty (30) bronchial asthma patients were recruited (with a mean age of 63SD±14.36, 16 males and 14 females) to test the pre-final version, and probing of each item was done to test the equivalence. It showed that the patient comprehended the intent behind each inquiry, and that was gauged on the Likert scale. A total of 102 adults (60.8% female and 39.2% male) with a mean age of 41±11 years were included in the study to examine test-retest reliability. Between the total scores obtained from the first and second applications of the questionnaire within a two-week period, there was no discernible variation. The internal consistency reliability (Cronbach´s alpha) was 0.79 and the Intra-class correlation coefficient was 1.000.

Conclusion: Marathi Version of the patient asthma knowledge questionnaire (PAKQ) is cross-culturally adapted and reliable; it will prove to be a beneficial tool to assess the disease-specific knowledge of bronchial asthma.

导言:患者教育是支气管哮喘临床治疗的基石。患者哮喘知识问卷是评估支气管哮喘患者疾病相关知识的有效而可靠的工具。根据我们的了解和文献检索,目前还没有马拉地语评估支气管哮喘患者哮喘知识的工具。由合格的翻译人员(T1 和 T2)根据指南进行正向和反向翻译。翻译人员和记录观察员(T12)对翻译版本进行综合。专家委员会提出建议,以制定最终版本。然后在 30 名支气管哮喘患者身上对预最终版本进行了测试。结果:招募了 30 名支气管哮喘患者(平均年龄为 63SD±14.36,男性 16 人,女性 14 人)对最终版本进行测试,并对每个项目进行了等效性测试。结果表明,患者理解了每项询问背后的意图,这是用李克特量表来衡量的。研究共纳入了 102 名成年人(女性占 60.8%,男性占 39.2%),平均年龄为 41±11 岁,以检验测试-再测可靠性。在两周时间内,第一次和第二次使用问卷所获得的总分之间没有明显差异。内部一致性可靠性(Cronbach's alpha)为 0.79,类内相关系数为 1.000:马拉地语版患者哮喘知识问卷(PAKQ)具有跨文化适应性和可靠性;它将被证明是评估支气管哮喘特定疾病知识的有益工具。
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引用次数: 0
Schizophrenia and medication adherence among the population in Morocco: a cross-sectional study at the University Psychiatric Center of Casablanca. 摩洛哥人群中的精神分裂症与服药依从性:卡萨布兰卡大学精神病学中心的一项横断面研究。
IF 0.9 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-22 eCollection Date: 2024-01-01 DOI: 10.11604/pamj.2024.48.123.39645
Imane Salihi, Nadia Attouche, Gladys Tsoumbou Bakana, Samira Nani, Mohamed Agoub, Khadija Mchichi Alami

Introduction: schizophrenia is a chronic, disabling, and serious disease. It represents a challenge because of its prevalence and its consequences in terms of morbidity and mortality for patients, but also for their families and society. Patients often fail to adhere to their treatment, and this has a severe negative effect on the prognosis of the disease. Thus, the identification of the predictive factors influencing this compliance is very important for adequate management and a favorable evolution. The aim of the study is to assess the predictive factors of non-adherence in patients with schizophrenia.

Methods: a cross-sectional study of 320 patients diagnosed with schizophrenia according to the DSM-5 criteria, was conducted at the University Psychiatric Centre of Casablanca, Morocco. Epidemiological, clinical, and therapeutic data were collected using a hetero-questionnaire, while medication adherence was assessed using the Medication Adherence Rating Scale (MARS). The positive and negative symptoms scale (PANSS) was used to assess the severity of symptoms in patients with schizophrenia.

Results: in our study, the total sample comprised 320 (100%) patients, classified into two groups: 82 (25.62%) were categorized as adherent, while 238 (74.38%) were non-adherent, and 72% were male. The non-adherent group was young (p=0.003), and a significant proportion had no educational background (p=0.015), lived alone (p=0,001), in urban areas (p=0.031), non-regular follow-up (p=0.045) and had a toxic history (p=0.0001), early age of onset of the disease (p=0.002). Moreover, this group exhibited more severe schizophrenic symptoms (p=0.02), lacked insight into their condition (p=0.046), and predominantly used typical antipsychotics (p=0.019) with a high frequency of intake (p=0.0001). Sedation emerged as a predominant side effect (p=0.036) of treatment. Notably, a high frequency of hospitalizations (p=0.005) exhibited a strong association with medication non-adherence. The mean age of the sample was 32.9 years (standard deviation: 10.8), with a mean age of disease onset reported at 25.5 years (standard deviation=4.9).

Conclusion: this study highlights the prevalence of non-adherence among patients with schizophrenia, with significant associations observed with demographic factors, the severity of symptoms, treatment patterns, and hospitalization frequency, emphasizing the urgent need for tailored interventions to enhance medication adherence and improve patient outcomes in managing schizophrenia.

导言:精神分裂症是一种慢性、致残性的严重疾病。由于其发病率及其对患者、患者家庭和社会造成的发病率和死亡率后果,精神分裂症是一项挑战。患者往往不能坚持治疗,这对疾病的预后产生了严重的负面影响。因此,确定影响治疗依从性的预测因素对于适当的管理和良好的发展非常重要。本研究旨在评估精神分裂症患者不坚持治疗的预测因素。方法:摩洛哥卡萨布兰卡大学精神病学中心对根据 DSM-5 标准诊断为精神分裂症的 320 名患者进行了横断面研究。研究采用异质问卷收集流行病学、临床和治疗数据,并使用药物依从性评定量表(MARS)评估药物依从性。结果:在我们的研究中,总样本包括 320 名(100%)患者,分为两组:82 名(25.62%)被归类为依从性患者,238 名(74.38%)为非依从性患者,其中 72% 为男性。非依从组患者年龄较轻(P=0.003),很大一部分没有教育背景(P=0.015),独居(P=0.001),居住在城市地区(P=0.031),没有定期随访(P=0.045),有中毒史(P=0.0001),发病年龄较早(P=0.002)。此外,这组患者表现出更严重的精神分裂症状(p=0.02),对自己的病情缺乏洞察力(p=0.046),主要使用典型抗精神病药物(p=0.019),服用频率高(p=0.0001)。镇静是治疗的主要副作用(p=0.036)。值得注意的是,高频率的住院治疗(p=0.005)与不坚持服药密切相关。样本的平均年龄为 32.9 岁(标准偏差:10.8),平均发病年龄为 25.5 岁(标准偏差=4.9)。结论:本研究强调了精神分裂症患者不坚持服药的普遍性,观察到不坚持服药与人口统计学因素、症状严重程度、治疗模式和住院频率有显著关联,强调迫切需要有针对性的干预措施,以提高患者的服药依从性,改善精神分裂症的治疗效果。
{"title":"Schizophrenia and medication adherence among the population in Morocco: a cross-sectional study at the University Psychiatric Center of Casablanca.","authors":"Imane Salihi, Nadia Attouche, Gladys Tsoumbou Bakana, Samira Nani, Mohamed Agoub, Khadija Mchichi Alami","doi":"10.11604/pamj.2024.48.123.39645","DOIUrl":"https://doi.org/10.11604/pamj.2024.48.123.39645","url":null,"abstract":"<p><strong>Introduction: </strong>schizophrenia is a chronic, disabling, and serious disease. It represents a challenge because of its prevalence and its consequences in terms of morbidity and mortality for patients, but also for their families and society. Patients often fail to adhere to their treatment, and this has a severe negative effect on the prognosis of the disease. Thus, the identification of the predictive factors influencing this compliance is very important for adequate management and a favorable evolution. The aim of the study is to assess the predictive factors of non-adherence in patients with schizophrenia.</p><p><strong>Methods: </strong>a cross-sectional study of 320 patients diagnosed with schizophrenia according to the DSM-5 criteria, was conducted at the University Psychiatric Centre of Casablanca, Morocco. Epidemiological, clinical, and therapeutic data were collected using a hetero-questionnaire, while medication adherence was assessed using the Medication Adherence Rating Scale (MARS). The positive and negative symptoms scale (PANSS) was used to assess the severity of symptoms in patients with schizophrenia.</p><p><strong>Results: </strong>in our study, the total sample comprised 320 (100%) patients, classified into two groups: 82 (25.62%) were categorized as adherent, while 238 (74.38%) were non-adherent, and 72% were male. The non-adherent group was young (p=0.003), and a significant proportion had no educational background (p=0.015), lived alone (p=0,001), in urban areas (p=0.031), non-regular follow-up (p=0.045) and had a toxic history (p=0.0001), early age of onset of the disease (p=0.002). Moreover, this group exhibited more severe schizophrenic symptoms (p=0.02), lacked insight into their condition (p=0.046), and predominantly used typical antipsychotics (p=0.019) with a high frequency of intake (p=0.0001). Sedation emerged as a predominant side effect (p=0.036) of treatment. Notably, a high frequency of hospitalizations (p=0.005) exhibited a strong association with medication non-adherence. The mean age of the sample was 32.9 years (standard deviation: 10.8), with a mean age of disease onset reported at 25.5 years (standard deviation=4.9).</p><p><strong>Conclusion: </strong>this study highlights the prevalence of non-adherence among patients with schizophrenia, with significant associations observed with demographic factors, the severity of symptoms, treatment patterns, and hospitalization frequency, emphasizing the urgent need for tailored interventions to enhance medication adherence and improve patient outcomes in managing schizophrenia.</p>","PeriodicalId":48190,"journal":{"name":"Pan African Medical Journal","volume":"48 ","pages":"123"},"PeriodicalIF":0.9,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11549242/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142630807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of the Khartoum war on dental education. 喀土穆战争对牙科教育的影响。
IF 0.9 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-07-19 eCollection Date: 2024-01-01 DOI: 10.11604/pamj.2024.48.119.44219
Nada Tawfig Hashim, Vivek Padmanabhan, Mariam Elhadi Elsheikh, Bakri Gobara Gismalla, Mohammed Mustahsen Rehman

The relentless conflict in Khartoum has severely crippled higher education, especially in specialized fields like dental education. The war has wreaked havoc on academic schedules, severely damaging infrastructure, and creating an atmosphere of pervasive uncertainty and stress for students and faculty alike. Academic continuity has been shattered, with courses and training programs facing frequent disruptions, leaving students struggling to complete their studies and gain essential practical experience. Faculty members, too, are under immense pressure, dealing with the dual burdens of maintaining educational standards and ensuring personal safety. This commentary delves into the devastating and far-reaching consequences of the ongoing conflict on dental education in Khartoum, highlighting the urgent need for comprehensive recovery and support strategies to restore this critical field.

喀土穆无休止的冲突严重削弱了高等教育,尤其是牙科教育等专业领域。战争对教学计划造成了严重破坏,严重破坏了基础设施,给学生和教师造成了普遍的不确定性和压力。教学的连续性遭到破坏,课程和培训计划经常中断,学生们既要完成学业,又要获得必要的实践经验。教职员工也承受着巨大的压力,既要维持教学标准,又要确保人身安全。这篇评论深入探讨了持续不断的冲突对喀土穆牙科教育造成的破坏性和深远影响,强调了恢复这一关键领域的全面恢复和支持战略的迫切需要。
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Pan African Medical Journal
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