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Sex-specific modulating role of social support in the associations between oxidative stress, inflammation, and telomere length in older adults. 社会支持对老年人氧化应激、炎症和端粒长度之间关系的调节作用具有性别特异性。
IF 2.8 3区 医学 Q2 PSYCHOLOGY, CLINICAL Pub Date : 2024-12-01 Epub Date: 2024-08-23 DOI: 10.1007/s10865-024-00515-0
Zhou Jin, Xuejian Liu, Haonan Guo, Sixuan Chen, Xianghe Zhu, Sipei Pan, Yili Wu

Telomere length, a biomarker of human aging, is related to adverse health outcomes. Growing evidence indicates that oxidative stress and inflammation contributes to telomere shortening, whereas social support may protect from telomere shortening. Despite sex differences in telomere length and social support, little is known about whether there are sex differences in the relationship between oxidative stress/inflammation and telomere length, and sex-specific moderating roles of social support in older adults. Using data from the National Health and Nutrition Examination Survey (NHANES) 1999-2002, this study assessed whether the associations between oxidative stress/inflammation and telomere length vary with sex and explored social support as a moderator in these associations among 2289 older adults. Oxidative stress was measured based on serum Gamma-glutamyl transferase (GGT), and inflammation was measured based on C-reactive protein (CRP). After adjusting for the covariates, GGT was significantly associated with telomere length in females only (β =  - 0.037, 95% CI =  - 0.070, - 0.005), while CRP was associated with telomere length in males only (β =  - 0.019, 95% CI =  - 0.035, - 0.002). Moreover, high social support mitigated the negative association between GGT and telomere length, which was more evident in females. Furthermore, social support moderated the association between CRP and telomere length in males aged 70 and above. Our findings indicated that biological mechanisms related to telomere length may vary with sex, while social support plays a sex-specific moderating role.

端粒长度是人类衰老的生物标志,与不良健康后果有关。越来越多的证据表明,氧化应激和炎症会导致端粒缩短,而社会支持可以防止端粒缩短。尽管端粒长度和社会支持存在性别差异,但人们对氧化应激/炎症和端粒长度之间的关系是否存在性别差异以及社会支持在老年人中的性别调节作用却知之甚少。本研究利用美国国家健康与营养调查(NHANES)1999-2002 年的数据,评估了氧化应激/炎症与端粒长度之间的关系是否随性别而变化,并探讨了社会支持在 2289 名老年人中对这些关系的调节作用。氧化应激根据血清γ-谷氨酰转移酶(GGT)进行测量,炎症根据C反应蛋白(CRP)进行测量。调整协变量后,GGT 仅与女性的端粒长度显著相关(β = - 0.037,95% CI = - 0.070,- 0.005),而 CRP 仅与男性的端粒长度相关(β = - 0.019,95% CI = - 0.035,- 0.002)。此外,高社会支持可减轻 GGT 与端粒长度之间的负相关,这种负相关在女性中更为明显。此外,在 70 岁及以上的男性中,社会支持缓和了 CRP 与端粒长度之间的关系。我们的研究结果表明,与端粒长度相关的生物机制可能因性别而异,而社会支持则起到了特定性别的调节作用。
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引用次数: 0
Caregiver burden in informal spousal caregivers predicts psychological and physical health in patients following coronary artery bypass graft surgery: a longitudinal clinical cohort study. 非正规配偶照顾者的照顾负担可预测冠状动脉旁路移植手术后患者的心理和生理健康状况:一项纵向临床队列研究。
IF 2.8 3区 医学 Q2 PSYCHOLOGY, CLINICAL Pub Date : 2024-12-01 Epub Date: 2024-08-25 DOI: 10.1007/s10865-024-00512-3
Claudio Singh Solorzano, Hannah Rowlands, Amy Ronaldson, Tara Kidd, Andrew Steptoe, Elizabeth Leigh, Marjan Jahangiri, Lydia Poole

Previous research has shown that informal caregiver burden can have deleterious effects on patient recovery; however, this relationship has yet to be investigated in patients undergoing coronary artery bypass graft (CABG) surgery. This study aimed to examine the impact of the change of caregiver burden from pre- to post-surgery on patients' mental and physical health after CABG surgery. Ninety patient-caregiver dyads were assessed one month before the surgery, two months and one year after the surgery. Caregivers completed the Oberst Burden Scale to measure caregiver burden. Patients completed the Beck Depression Inventory to measure depressive symptoms, a subscale of the Hospital Anxiety and Depression Scale to measure anxiety symptoms, the Short Form-12 health assessment to measure health-related quality of life, and the Coronary Revascularisation Outcomes Questionnaire to measure surgery symptoms. Hierarchical linear regression analyses were conducted to explore the association between change in caregiver burden and post-surgery patient outcomes. A greater increase in caregiver burden from pre- to two-months post-surgery significantly predicted higher patients' depressive symptoms (β = 0.179, p = 0.010), anxiety symptoms (β = 0.114, p = 0.017), reported post-surgery symptoms (β = 0.335, p = 0.008) and reduced physical health-related quality of life (β = -0.358, p = 0.003), after controlling for a wide range of covariates. These findings were not replicated at a one-year follow-up. These results provide insights into the impact of caregiver burden on patient distress following CABG surgery, supporting the idea of psychological support interventions for caregivers to increase patients' short-term recovery outcomes.

以往的研究表明,非正式护理人员的负担会对患者的康复产生有害影响;然而,对于接受冠状动脉旁路移植手术(CABG)的患者,这种关系尚未得到研究。本研究旨在探讨从手术前到手术后照顾者负担的变化对冠状动脉旁路移植手术后患者身心健康的影响。研究人员分别在手术前一个月、手术后两个月和手术后一年对 90 个患者-护理者二元组进行了评估。护理人员完成了奥伯斯特负担量表,以测量护理人员的负担。患者填写贝克抑郁量表以测量抑郁症状,填写医院焦虑抑郁量表的一个分量表以测量焦虑症状,填写简表-12健康评估表以测量与健康相关的生活质量,填写冠状动脉血运重建结果问卷以测量手术症状。我们进行了层次线性回归分析,以探讨护理人员负担的变化与手术后患者预后之间的关系。从手术前到手术后两个月,护理人员负担的增加显著预示着患者抑郁症状(β = 0.179,p = 0.010)、焦虑症状(β = 0.114,p = 0.017)、报告的手术后症状(β = 0.335,p = 0.008)和身体健康相关生活质量的降低(β = -0.358,p = 0.003),在控制了多种协变量后,护理人员负担的增加显著预示着患者抑郁症状(β = 0.179,p = 0.010)、焦虑症状(β = 0.114,p = 0.017)、报告的手术后症状(β = 0.335,p = 0.008)和身体健康相关生活质量的降低(β = -0.358,p = 0.003)。这些结果在一年的随访中没有得到验证。这些结果提供了有关护理人员负担对 CABG 手术后患者痛苦的影响的见解,支持对护理人员进行心理支持干预以提高患者短期康复效果的观点。
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引用次数: 0
Risk and demographic factors associated with STI testing adherence among non-single men who have sex with men (MSM) in the United States. 美国非单身男男性行为者(MSM)坚持性传播感染检测的相关风险和人口因素。
IF 2.8 3区 医学 Q2 PSYCHOLOGY, CLINICAL Pub Date : 2024-12-01 Epub Date: 2024-10-02 DOI: 10.1007/s10865-024-00524-z
Minhao Dai, Shilin Xia, Christopher Calabrese, Xin Ma, Tianen Chen

Though men who have sex with men (MSM) are disproportionately affected by sexually transmitted infections (STIs), factors that impact STI testing adherence among non-single MSM remain under-explored. While being in a relationship per se does not necessarily increase one's risk for STIs, certain behavioral risks and demographic factors may impact STI testing adherence. Through a sample of 296 non-single MSM located in the United States, we examined key behavioral and demographic factors and their associations with adherence to CDC's STI testing guidelines. Overall, the results showed inconsistent STI testing adherence rates among divergent subgroups of higher-risk non-single MSM. First, non-single MSM who take PrEP were more likely to adhere to STI testing and showed significantly higher adherence rates than those who do not take PrEP, but adherence rates were not related to nor significantly different than those who reported extra-relational sex or condomless anal sex. Further, STI testing adherence was positively associated with having a shorter relationship length, identifying as non-White, and living in an LGBTQ+-friendly neighborhood. Practical implications and recommendations for clinical practices, persuasive messages, and promotion strategies are discussed.

尽管男男性行为者(MSM)受性传播感染(STI)的影响尤为严重,但影响非单身男男性行为者坚持 STI 检测的因素仍未得到充分探讨。虽然恋爱关系本身并不一定会增加感染性传播疾病的风险,但某些行为风险和人口因素可能会影响性传播疾病检测的依从性。通过对美国 296 名非单身男男性行为者的抽样调查,我们研究了关键的行为和人口因素及其与遵守美国疾病预防控制中心性传播感染检测指南的关系。总体而言,研究结果表明,在不同的高风险非单身 MSM 亚群中,性传播感染检测的坚持率并不一致。首先,服用 PrEP 的非单身 MSM 更有可能坚持进行 STI 检测,且坚持率明显高于未服用 PrEP 的 MSM,但坚持率与报告发生关系外性行为或无安全套肛交的 MSM 无关,也无明显差异。此外,性传播感染检测的坚持率与恋爱时间较短、非白人身份以及居住在 LGBTQ+ 友好社区呈正相关。本文讨论了临床实践、说服信息和推广策略的实际意义和建议。
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引用次数: 0
Strength-based strategies for addressing racial stressors in African American families: lessons learned from developing the LEADS health promotion intervention. 解决非裔美国人家庭种族压力的强势策略:从制定 LEADS 健康促进干预措施中汲取的经验教训。
IF 2.8 3区 医学 Q2 PSYCHOLOGY, CLINICAL Pub Date : 2024-12-01 Epub Date: 2024-08-10 DOI: 10.1007/s10865-024-00509-y
Timothy Simmons, Mary Quattlebaum, Pamela Martin, Dawn K Wilson

Recognizing the real-life impact of racial stress on physical and psychological health is vital for creating impactful health promotion interventions among African American families. Despite the known link between racial stress and poor physical health outcomes, no existing intervention to date has targeted stress management strategies to buffer racial stress and build positive health behaviors among African American families. The current study outlines the lessons learned throughout the development of the Linking Exercise for Advancing Daily Stress (LEADS) Management and Resilience program, a 10-week family-based health promotion, stress management, and resilience intervention that aimed to improve physical activity, healthy eating, and well-being among African American adolescents and parents. We highlight the evolution of the LEADS intervention from a health promotion and stress management intervention to a culturally salient health promotion, stress management, and resilience intervention utilizing community-based participatory research strategies. This paper chronicles our systematic journey in making those changes and the lessons we learned along the way. We provide specific recommendations and implications for future health promotion interventions developed for African American families. Overall, we argue for a research orientation that respects cultural and racial contexts, embraces diversity within research teams and self-reflection, recognizes the heterogeneity among African American populations, and applies strength-based approaches.

认识到种族压力在现实生活中对身心健康的影响,对于在非裔美国人家庭中制定有影响力的健康促进干预措施至关重要。尽管种族压力与不良身体健康结果之间存在已知的联系,但迄今为止,还没有任何现有干预措施针对压力管理策略,以缓冲种族压力并在非裔美国人家庭中培养积极的健康行为。本研究概述了在开发 "链接运动促进日常压力(LEADS)管理和复原力计划 "过程中吸取的经验教训,该计划是一项为期 10 周的基于家庭的健康促进、压力管理和复原力干预措施,旨在改善非裔美国青少年和家长的体育锻炼、健康饮食和幸福感。我们重点介绍了 LEADS 干预方案从健康促进和压力管理干预方案发展为具有文化特色的健康促进、压力管理和抗逆力干预方案的过程,该方案采用了基于社区的参与式研究策略。本文记录了我们进行这些变革的系统历程以及我们在这一过程中学到的经验教训。我们为今后针对非裔美国人家庭制定健康促进干预措施提供了具体建议和启示。总之,我们主张尊重文化和种族背景的研究方向,接受研究团队和自我反思的多样性,承认非裔美国人的异质性,并采用基于力量的方法。
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引用次数: 0
A systematic comparison of additive and interaction approaches to modeling the effects of syndemic problems on HIV outcomes in South Africa. 在南非,对综合症问题对艾滋病结果的影响进行建模时,对加法和互动方法进行了系统比较。
IF 4.6 3区 医学 Q2 PSYCHOLOGY, CLINICAL Pub Date : 2024-12-01 Epub Date: 2024-09-21 DOI: 10.1007/s10865-024-00517-y
Jasper S Lee, Sierra A Bainter, Alexander C Tsai, Lena S Andersen, Amelia M Stanton, Jessica F Magidson, Ashraf Kagee, Julian May, John A Joska, Conall O'Cleirigh, Steven A Safren

Much of the research on the effects of syndemics on HIV outcomes has utilized an additive approach. However, interaction effects may better account for syndemic synergy than an additive approach, but it remains difficult to specify interaction effects without empirical guidance. We sought to systematically compare additive and interaction effects approaches to modeling the effects of syndemic problems on antiretroviral therapy (ART) using empirically specified interaction terms. Participants were 194 people with HIV (PWH) who received HIV care in Khayelitsha, South Africa. In a series of linear regression models, we examined ten syndemic problems: depression, alcohol use, intimate partner violence (IPV), post-traumatic stress, social anxiety, substance use, food insecurity, poverty, housing instability, and structural barriers to care. Depression, substance use, and food insecurity were selected for interaction terms based on a prior network analysis, which found these problems to be most central. The additive models did not produce statistically significant findings. However, the interaction effects models yielded significant interaction terms in both the full model and a parsimonious model. There was a statistically significant effect of the interaction between depression and food insecurity on ART adherence (b = 0.04, Robust SE = 0.02, 95%CI [0.001-0.08], p = .012). This pattern of results was replicated in the parsimonious model. Findings suggest that when feasible, interaction effects approaches may be a helpful syndemic modeling technique. Results may inform future intervention targets, such as depression and food insecurity, and the importance of addressing both structural and psychosocial syndemic problems.

关于综合症对艾滋病结果影响的研究大多采用加法方法。然而,与加法相比,交互作用可能更能说明综合症的协同作用,但在没有经验指导的情况下,要明确交互作用仍然很困难。我们试图系统地比较加法效应和交互效应方法,利用经验指定的交互项来模拟综合症问题对抗逆转录病毒疗法(ART)的影响。研究对象是在南非卡耶利沙接受艾滋病治疗的 194 名艾滋病病毒感染者(PWH)。在一系列线性回归模型中,我们研究了十个综合问题:抑郁、酗酒、亲密伴侣暴力(IPV)、创伤后应激反应、社会焦虑、药物使用、食物无保障、贫困、住房不稳定以及护理的结构性障碍。根据先前的网络分析,抑郁、药物使用和食物无保障被选为交互项,该分析发现这些问题最为核心。加法模型没有得出具有统计学意义的结果。然而,交互效应模型在完整模型和简化模型中都产生了显著的交互项。抑郁与食物无保障之间的交互作用对坚持抗逆转录病毒疗法有显著的统计学影响(b = 0.04,稳健 SE = 0.02,95%CI [0.001-0.08],p = .012)。这一结果模式在拟合模型中得到了复制。研究结果表明,在可行的情况下,交互效应方法可能是一种有用的综合症建模技术。研究结果可为未来的干预目标(如抑郁症和粮食不安全)提供参考,并说明同时解决结构性和社会心理综合症问题的重要性。
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引用次数: 0
Physical activity interventions: an update on advancing sedentary time, technology, and dissemination and implementation research. 体育锻炼干预措施:关于延长久坐时间、技术以及传播和实施研究的最新进展。
IF 2.8 3区 医学 Q2 PSYCHOLOGY, CLINICAL Pub Date : 2024-11-10 DOI: 10.1007/s10865-024-00533-y
Beth A Lewis, Melissa A Napolitano, Matthew P Buman, David M Williams, Claudio R Nigg

Approximately 28% of American adults meet both the physical activity (PA) and strength training guidelines despite the numerous health benefits associated with a physically active lifestyle. The purpose of this paper is to provide an update of the 2017 Society of Behavioral Medicine PA Special Interest Group article that outlined future directions in sedentary time reduction interventions, technology-based PA interventions, and the dissemination and implementation of PA interventions. Since the prior review, there has been significant progress on effective interventions for reducing sedentary time. However, there has been less progress for improving the specificity of sedentary time guidelines. There has been a dramatic increase in the number of studies examining PA mHealth interventions and support for mHealth intervention has generally been positive, though sustaining engagement in mHealth interventions remains a challenge. Promising newer technologies that have been explored more extensively since the prior review including artificial intelligence (AI). Knowledge of how to implement and scale-up effective PA interventions has also increased. Several current trends in PA intervention research that continue to advance the field include examining the moderating effect of the built environment on the effectiveness of behavioral interventions, cultural tailoring of interventions, Just in Time Adaptive Interventions (JITAIs), and exercise snacks (vigorous intensity PA sessions that are less than one minute). Overall, there has been significant progress in the PA intervention field but significant work remains for creating effective interventions that can be readily implemented into real world settings.

尽管体育锻炼的生活方式对健康有诸多益处,但约有 28% 的美国成年人同时符合体育锻炼(PA)和力量训练指南的要求。本文旨在更新 2017 年行为医学会 PA 小组的文章,该文章概述了减少久坐时间干预措施、基于技术的 PA 干预措施以及 PA 干预措施的传播和实施的未来方向。自上次回顾以来,减少久坐时间的有效干预措施取得了重大进展。然而,在提高久坐时间指南的针对性方面,进展较小。对运动量移动保健干预进行研究的数量急剧增加,对移动保健干预的支持一般都是积极的,但持续参与移动保健干预仍是一项挑战。自上次审查以来,对包括人工智能(AI)在内的新兴技术进行了更广泛的探索,这些技术前景广阔。关于如何实施和推广有效的运动锻炼干预措施的知识也有所增加。当前,运动锻炼干预研究的几个趋势继续推动着这一领域的发展,包括研究建筑环境对行为干预效果的调节作用、干预的文化定制、适时适应性干预(JITAIs)和运动点心(少于一分钟的高强度运动锻炼)。总体而言,运动锻炼干预领域已经取得了重大进展,但要创建可在现实环境中随时实施的有效干预措施,仍有大量工作要做。
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引用次数: 0
Mobile apps for diabetes self-management: An updated review of app features and effectiveness. 用于糖尿病自我管理的移动应用程序:对应用程序功能和有效性的最新审查。
IF 2.8 3区 医学 Q2 PSYCHOLOGY, CLINICAL Pub Date : 2024-11-03 DOI: 10.1007/s10865-024-00525-y
Joyce A Corsica, Mackenzie C Kelly, Lauren E Bradley, Madeline M Konsor, Elizabeth J Wilson, Isabel C Quinones, Rebecca W Jeddi, Megan A Markey

Self-management of diabetes is extremely challenging and non-adherence is common. Health consequences are significant for those unable to adhere to the complex treatment regimen, which includes regular oral medication and/or insulin use, frequent blood sugar checks, strict dietary management, and regular physical activity. Mobile applications (apps) present a tremendous opportunity to help patients improve adherence to these behaviors. The availability of commercial diabetes self-management apps is increasing exponentially, making it difficult for patients and providers to stay informed about app options and benefits. Previous reviews have described commercial diabetes apps and their features and usability for patients with diabetes. A smaller number have reviewed the effectiveness of these apps in improving blood glucose as well as other aspects of diabetes management. The aim of this article is to update our 2016 review, summarize the results of new reviews, review outcomes of diabetes apps described in the literature, and offer recommendations for app features, effectiveness research, and marketing in apps for diabetes self-management. Although higher-quality research is needed, current reviews suggest that many diabetes apps are effective in lowering HbA1c. Recommendations for future research include reporting critical details such as patient demographics and intervention elements and designing studies to identify the most effective components of diabetes management apps. Furthermore, clearly labeling apps that have data supporting clinical efficacy in app stores would allow both providers and patients to easily identify apps that might be most beneficial. Future research should explore the use of apps for the prevention of diabetes in individuals diagnosed with prediabetes.

糖尿病的自我管理极具挑战性,不坚持治疗也很常见。复杂的治疗方案包括定期口服药物和/或使用胰岛素、经常检查血糖、严格控制饮食和定期进行体育锻炼。移动应用程序(Apps)为帮助患者更好地坚持这些行为提供了巨大的机会。商业糖尿病自我管理应用程序的可用性正在急剧增加,这使得患者和医疗服务提供者很难了解应用程序的选择和益处。以往的评论描述了商业糖尿病应用程序及其功能和对糖尿病患者的可用性。较少一部分评论了这些应用程序在改善血糖以及糖尿病管理其他方面的有效性。本文旨在更新我们 2016 年的综述,总结新综述的结果,回顾文献中描述的糖尿病应用程序的结果,并就糖尿病自我管理应用程序的功能、有效性研究和营销提出建议。尽管还需要更高质量的研究,但目前的综述表明,许多糖尿病应用程序能有效降低 HbA1c。对未来研究的建议包括报告关键细节,如患者人口统计学和干预要素,并设计研究以确定糖尿病管理应用程序中最有效的组成部分。此外,在应用程序商店中明确标注具有临床疗效数据支持的应用程序,将使医疗服务提供者和患者能够轻松识别可能最有益的应用程序。未来的研究应探索如何使用应用程序预防糖尿病前期患者的糖尿病。
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引用次数: 0
The impact of exercise interventions on sleep in adult populations with depression, anxiety, or posttraumatic stress: review of the current evidence and future directions. 运动干预对患有抑郁症、焦虑症或创伤后应激反应的成年人群睡眠的影响:当前证据回顾与未来方向。
IF 2.8 3区 医学 Q2 PSYCHOLOGY, CLINICAL Pub Date : 2024-10-30 DOI: 10.1007/s10865-024-00532-z
Kristin L Szuhany, Abigail J Sullivan, Joshua L Gills, M Alexandra Kredlow

Consistent evidence suggests that exercise leads to improvements in subjective sleep quality and also objective sleep metrics in non-psychiatric adult populations. However, the degree to which exercise provides sleep benefits for adults with psychiatric disorders is less known, despite the potential benefits given that sleep disturbance is prevalent in these populations. In this narrative review, we synthesize results of randomized controlled trials examining the influence of aerobic and/or resistance exercise interventions on sleep outcomes in adult psychiatric populations. We specifically focus on populations with elevated symptoms or diagnoses of depression, anxiety, or posttraumatic stress disorder. A systematic search through June 2024 yielded 26 relevant trials. Overall, most trials reported improvement of subjective sleep quality after aerobic and/or resistance exercise programs in samples with depression. Similar effects were observed for posttraumatic stress; however, larger trials are needed. Further research is needed to examine the impact of exercise on sleep in anxiety populations as only one trial with mixed results was identified. Results were more equivocal for the subpopulation of adult women with perinatal or postpartum depression, demonstrating the importance of understanding exercise effects on sleep in specific subpopulations. Few studies examined objective sleep outcomes, impact of acute exercise on next day sleep, or the interplay between exercise, sleep, and psychiatric symptom changes, all important areas of future research. Other implications and future directions are discussed, including potential moderators and mechanisms of action that warrant further study to better understand how exercise interventions may optimally target sleep in psychiatric populations.

一致的证据表明,在非精神疾病成年人群中,运动可改善主观睡眠质量和客观睡眠指标。然而,对于患有精神疾病的成年人来说,运动能在多大程度上改善睡眠却鲜为人知,尽管这些人群普遍存在睡眠障碍,而运动能为他们带来潜在的益处。在这篇叙述性综述中,我们综合了随机对照试验的结果,这些试验研究了有氧运动和/或阻力运动干预对成年精神病患者睡眠结果的影响。我们特别关注抑郁症、焦虑症或创伤后应激障碍症状或诊断升高的人群。截至 2024 年 6 月的系统检索共获得 26 项相关试验。总体而言,大多数试验报告了抑郁症样本在接受有氧运动和/或阻力运动项目后主观睡眠质量的改善情况。在创伤后应激障碍方面也观察到了类似的效果;不过,还需要进行更大规模的试验。需要进一步研究运动对焦虑人群睡眠的影响,因为只发现了一项结果不一的试验。对于患有围产期或产后抑郁症的成年女性亚群来说,研究结果更加模棱两可,这表明了解运动对特定亚群睡眠影响的重要性。很少有研究对客观睡眠结果、急性运动对第二天睡眠的影响或运动、睡眠和精神症状变化之间的相互作用进行研究,而这些都是未来研究的重要领域。研究还讨论了其他影响和未来方向,包括值得进一步研究的潜在调节因素和作用机制,以更好地了解运动干预如何能最佳地针对精神病人群的睡眠。
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引用次数: 0
Exposure to firearm injury and suicide in a rural Pennsylvania county: implications for mental and behavioral health. 宾夕法尼亚州一个农村地区的枪支伤害和自杀事件:对心理和行为健康的影响。
IF 2.8 3区 医学 Q2 PSYCHOLOGY, CLINICAL Pub Date : 2024-10-28 DOI: 10.1007/s10865-024-00529-8
Richard Stansfield, Daniel C Semenza, Devon Ziminski

To evaluate the association between self-reported gun violence exposures and mental health and behavioral health indicators in a rural population. Using cross-sectional survey responses from 630 residents of a rural county in Pennsylvania, logistic regression models estimate the likelihood of residents indicating moderate or severe levels of health outcomes as a function of gun violence exposure. We control for a series of variables related to gun ownership, behavior, history with firearms and demographic characteristics. Personal firearm victimization was associated with self-reported depressive symptoms and interrupted sleep. Secondary exposure to firearm violence, particularly exposure to friends attempting or completing a suicide, was associated with higher odds of reporting severe levels (14 days or more in the past month) of depressive symptoms, anxiety, and poor sleep. For firearm suicide involving a friend or family member, the odds of reporting severe levels of all three outcomes are 3 times greater (OR 2.984, 95% CI 1.457-6.108). For each additional firearm exposure, the odds of experiencing severe levels of mental health and sleep difficulties are 1.4 times greater (OR 1.384, 95% CI 1.115-1.720). Cumulative exposures also increase the odds of reporting binge drinking and drug use. Firearm violence exposure was associated with adverse health indicators in this rural population. Approaches to counter the effects of cumulative firearm exposure and firearm suicide exposure, including reinvigorating community spaces and strengthening social supports, may help to reduce mental health burden in rural communities.

评估农村人口自我报告的枪支暴力暴露与心理健康和行为健康指标之间的关联。利用宾夕法尼亚州一个农村县 630 名居民的横截面调查反馈,通过逻辑回归模型估算出居民表示中度或重度健康后果的可能性与枪支暴力暴露的函数关系。我们控制了一系列与持枪、行为、持枪史和人口特征相关的变量。个人枪支受害与自我报告的抑郁症状和睡眠中断有关。二次接触枪支暴力,特别是接触试图自杀或完成自杀的朋友,与较高的抑郁症状、焦虑和睡眠不佳报告几率(过去一个月内达到或超过 14 天)相关。对于涉及朋友或家人的持枪自杀,报告这三种结果的严重程度的几率要高出 3 倍(OR 2.984,95% CI 1.457-6.108)。每多接触一次枪支,出现严重心理健康和睡眠困难的几率就会增加 1.4 倍(OR 1.384,95% CI 1.115-1.720)。累积暴露也会增加报告酗酒和吸毒的几率。在这一农村人口中,枪支暴力暴露与不良健康指标相关。消除累积枪支暴露和枪支自杀暴露影响的方法,包括重振社区空间和加强社会支持,可能有助于减轻农村社区的心理健康负担。
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引用次数: 0
Personality and cardiovascular mortality risk: a multi-cohort analysis in individuals with and without pre-existing cardiovascular disease. 性格与心血管死亡风险:对已患和未患心血管疾病者的多队列分析。
IF 2.8 3区 医学 Q2 PSYCHOLOGY, CLINICAL Pub Date : 2024-10-28 DOI: 10.1007/s10865-024-00528-9
Markus Jokela, Laura Pulkki-Råback, Marko Elovainio, G David Batty, Mika Kivimäki

This study investigated the associations between personality traits of the Five Factor Model and cardiovascular mortality, with a specific focus on whether pre-existing cardiovascular conditions modified these associations. We used data from 43,027 participants across five cohort studies: Health and Retirement Study (HRS); Wisconsin Longitudinal Study (WLS); National Social Life, Health, and Aging Project (NSHAP); Midlife in the United States (MIDUS); Household, Income, and Labour Dynamics in Australia (HILDA) with a mean age 55.9 years and 6493 individuals with pre-existing cardiovascular disease. We conducted meta-analyses examining conscientiousness, emotional stability, agreeableness, openness to experience, and extraversion in relation to mortality due to coronary heart disease and stroke. During a mean follow-up of 12.1 years, 1620 participants died from coronary heart disease and 454 from stroke. Lower conscientiousness was associated with higher mortality risk from both coronary heart disease (hazard ratio per 1SD = 0.82, 95%CI = 0.75-0.90) and stroke (HR = 0.84, CI = 0.72-0.99). Lower emotional stability predicted increased coronary heart disease mortality (HR = 0.91, CI = 0.85-0.97). The association between conscientiousness and cardiovascular mortality did not differ between individuals with or without baseline cardiovascular conditions. In addition, adjustments for health behaviors and other covariates only slightly attenuated this association. Other personality traits were not associated with cardiovascular disease mortality. Our findings highlight the role of low conscientiousness, and to a lesser extent low emotional stability, in the development and progression of fatal cardiovascular disease through pathways that may extend beyond established health behaviors.

本研究调查了五因素模型中的人格特质与心血管死亡率之间的关系,特别关注已有的心血管疾病是否会改变这些关系。我们使用了五项队列研究中 43027 名参与者的数据:健康与退休研究(HRS);威斯康星纵向研究(WLS);国家社会生活、健康和老龄化项目(NSHAP);美国中年研究(MIDUS);澳大利亚家庭、收入和劳动力动态研究(HILDA)中的 43027 名参与者的数据,这些参与者的平均年龄为 55.9 岁,其中 6493 人已患有心血管疾病。我们对自觉性、情绪稳定性、合意性、经验开放性和外向性与冠心病和中风死亡率的关系进行了荟萃分析。在平均 12.1 年的随访期间,有 1620 人死于冠心病,454 人死于中风。较低的自觉性与较高的冠心病(每 1SD 危险比 = 0.82,95%CI = 0.75-0.90)和中风(HR = 0.84,CI = 0.72-0.99)死亡风险相关。情绪稳定性越低,冠心病死亡率越高(HR = 0.91,CI = 0.85-0.97)。自觉性与心血管死亡率之间的关系在有或没有心血管基线状况的个体之间没有差异。此外,对健康行为和其他协变量的调整也只是稍微削弱了这种关联。其他人格特质与心血管疾病死亡率无关。我们的研究结果凸显了低自觉性(其次是低情绪稳定性)在致命性心血管疾病的发生和发展中的作用,其途径可能超出了既定的健康行为。
{"title":"Personality and cardiovascular mortality risk: a multi-cohort analysis in individuals with and without pre-existing cardiovascular disease.","authors":"Markus Jokela, Laura Pulkki-Råback, Marko Elovainio, G David Batty, Mika Kivimäki","doi":"10.1007/s10865-024-00528-9","DOIUrl":"https://doi.org/10.1007/s10865-024-00528-9","url":null,"abstract":"<p><p>This study investigated the associations between personality traits of the Five Factor Model and cardiovascular mortality, with a specific focus on whether pre-existing cardiovascular conditions modified these associations. We used data from 43,027 participants across five cohort studies: Health and Retirement Study (HRS); Wisconsin Longitudinal Study (WLS); National Social Life, Health, and Aging Project (NSHAP); Midlife in the United States (MIDUS); Household, Income, and Labour Dynamics in Australia (HILDA) with a mean age 55.9 years and 6493 individuals with pre-existing cardiovascular disease. We conducted meta-analyses examining conscientiousness, emotional stability, agreeableness, openness to experience, and extraversion in relation to mortality due to coronary heart disease and stroke. During a mean follow-up of 12.1 years, 1620 participants died from coronary heart disease and 454 from stroke. Lower conscientiousness was associated with higher mortality risk from both coronary heart disease (hazard ratio per 1SD = 0.82, 95%CI = 0.75-0.90) and stroke (HR = 0.84, CI = 0.72-0.99). Lower emotional stability predicted increased coronary heart disease mortality (HR = 0.91, CI = 0.85-0.97). The association between conscientiousness and cardiovascular mortality did not differ between individuals with or without baseline cardiovascular conditions. In addition, adjustments for health behaviors and other covariates only slightly attenuated this association. Other personality traits were not associated with cardiovascular disease mortality. Our findings highlight the role of low conscientiousness, and to a lesser extent low emotional stability, in the development and progression of fatal cardiovascular disease through pathways that may extend beyond established health behaviors.</p>","PeriodicalId":48329,"journal":{"name":"Journal of Behavioral Medicine","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142523366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Journal of Behavioral Medicine
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