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Superwoman schema and metabolic syndrome in Black adolescent girls. 黑人少女的女超人图式与代谢综合征。
IF 2.9 3区 医学 Q2 PSYCHOLOGY, CLINICAL Pub Date : 2025-10-01 Epub Date: 2025-07-09 DOI: 10.1007/s10865-025-00584-9
Edith Chen, Jungwon Kim, Jayson Law, Vanessa Obi, Shanti U Gallivan, Robin Hayen

This study investigated associations between the Superwoman schema (socialized expectations to project strength and exhibit a determination to succeed, while at the same time helping others and suppressing one's emotions) and metabolic syndrome (MetS, a cluster of risk factors for diabetes, heart disease, and stroke detectable in childhood) across the period of adolescence. A sample of 256 Black adolescent girls (ages 14-19), all from lower-income households (≤ 2 × poverty threshold) was recruited for a cross-sectional study. Adolescents completed the Superwoman schema questionnaire, and MetS was measured using International Diabetes Federation criteria. Analyses posed a developmental question of whether associations varied by age across the period of adolescence. Age by Superwoman schema interactions were found, such that in younger adolescent girls, higher scores on the Superwoman schema questionnaire were associated with better cardiometabolic health (lower levels of MetS); however, by older adolescence, higher Superwoman schema scores were associated with worse cardiometabolic health (higher MetS). Psychologically, at older ages, a higher Superwoman schema score also was associated with experiencing greater conflict across life domains and with lower levels of perceived control. Overall these patterns suggest that a critical switch from the Superwoman schema being beneficial to being detrimental may occur some time during late adolescence. These findings suggest the importance of developing ways to cultivate and sustain the early beneficial aspects of a Superwoman schema as Black girls transition into adulthood.

本研究调查了青春期女超人图式(社会期望展现力量并表现出成功的决心,同时帮助他人并抑制自己的情绪)与代谢综合征(MetS,儿童时期可检测到的糖尿病、心脏病和中风的一系列危险因素)之间的关系。样本为256名黑人少女(14-19岁),均来自低收入家庭(≤2倍贫困线)进行横断面研究。青少年完成女超人图式问卷,并使用国际糖尿病联合会的标准测量代谢当量。分析提出了一个发展问题,即这种联系是否会随着青春期的年龄而变化。年龄与女超人图式的相互作用有关,例如,在年轻的青春期女孩中,女超人图式问卷得分越高,心脏代谢健康状况越好(MetS水平越低);然而,到了青春期后期,女超人图式得分越高,心脏代谢健康状况越差(MetS越高)。从心理上讲,在年龄较大时,女超人图式得分越高,在生活领域中经历的冲突越多,感知到的控制水平越低。总的来说,这些模式表明,从有益到有害的女超人图式的关键转变可能发生在青春期后期的某个时候。这些发现表明,在黑人女孩进入成年期的过程中,培养和维持女超人模式早期有益方面的方法很重要。
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引用次数: 0
A qualitative analysis of family experiences across diabetes-specific family functioning types during a family-focused intervention for adults with type 2 diabetes. 在以家庭为中心的2型糖尿病成人干预期间,对糖尿病特定家庭功能类型的家庭经历进行定性分析。
IF 2.9 3区 医学 Q2 PSYCHOLOGY, CLINICAL Pub Date : 2025-10-01 Epub Date: 2025-08-14 DOI: 10.1007/s10865-025-00594-7
McKenzie K Roddy, Erin M Bergner, Cynthia A Berg, Lindsay S Mayberry

Numerous dimensions of family involvement are important for chronic illness management. A recently developed and validated typology of diabetes-specific family functioning organizes these dimensions into four meaningful types (Collaborative & Helpful, Critically Involved, Satisfied with Low Involvement, and Want More Involvement). These types represent patterns of associations across dimensions of family involvement and synthesize these multiple dimensions of functioning into usable categories. The current study had two primary aims: first, to use qualitative data to enhance the quantitative understanding of types; and second, to describe qualitatively participants' own experiences with their family during a 9 month family-focused intervention (and 6 month follow-up) based on their diabetes-specific family functioning type at enrollment. Adults with type 2 diabetes (T2D) who participated in Family/Friend Activation to Motivate Self-care (FAMS), a family-focused self-care support intervention, were eligible. We recruited 77 participants across types to participate in semi-structured interviews at the completion of the follow-up. We found consistencies across types and differences between types. Regardless of type, harmful family involvement was described, but adults with T2D were hesitant to label it as such. Communication about diabetes and health increased during FAMS, but topics varied across types. Adults with T2D received more support from their families across time, though preference for emotional or instrumental support varied across types. This study qualitatively validated the typology tool paving the way for future use in intervention tailoring.

家庭参与的许多方面对慢性病管理都很重要。最近发展和验证的糖尿病特定家庭功能类型将这些维度分为四种有意义的类型(协作和帮助,批判性参与,满足于低参与和希望更多参与)。这些类型代表了跨家庭参与维度的关联模式,并将这些功能的多个维度合成为可用的类别。目前的研究有两个主要目的:第一,使用定性数据来加强对类型的定量理解;第二,定性描述参与者在9个月的以家庭为中心的干预(和6个月的随访)中与家人的经历,这是基于他们在入组时的糖尿病特定家庭功能类型。参加以家庭为中心的自我保健支持干预的家庭/朋友激活激励自我保健(FAMS)的2型糖尿病成人(T2D)符合条件。我们招募了77名不同类型的参与者在随访结束时参加半结构化访谈。我们发现了不同类型之间的一致性和不同类型之间的差异。无论何种类型,有害的家庭参与都被描述,但患有T2D的成年人不愿将其标记为这样。在FAMS期间,关于糖尿病和健康的交流有所增加,但不同类型的话题有所不同。随着时间的推移,患有T2D的成年人从家庭获得了更多的支持,尽管对情感或工具支持的偏好因类型而异。本研究定性地验证了类型学工具,为将来在干预裁剪中使用铺平了道路。
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引用次数: 0
Positive emotional well-being and glucose control in a nationwide sample. 积极情绪健康和血糖控制在全国范围内的样本。
IF 2.9 3区 医学 Q2 PSYCHOLOGY, CLINICAL Pub Date : 2025-10-01 Epub Date: 2025-08-14 DOI: 10.1007/s10865-025-00588-5
Yasmin Shemali, Tasneem Khambaty, Zachary Goodman, Gail Ironson

To investigate the link between HbA1c, a marker of glucose control, and positive emotional well-being (PEWB). Data were from a nationwide survey (N = 1933) which included an older, chronically ill subgroup (N = 905). Two aspects of PEWB were assessed via cross-sectional regression analyses predicting HbA1c from positive affect and life satisfaction individually, controlling for demographic variables. HbA1c was analyzed via blood-spot from a finger-prick. The mediating role of health behaviors (smoking, alcohol, BMI, and moderate exercise) were also examined. Higher positive affect and life satisfaction were significantly related to lower HbA1c in the overall and older, chronically ill samples controlling for demographics, as well as health behaviors and depression. Individuals with lower positive affect and lower life satisfaction were at increased odds of having clinically elevated HbA1c (> 6.5), indicative of diabetes, in both the overall sample (OR = 1.37; and OR = 1.13) and the chronically ill, older sample (OR = 1.59; and OR = 1.14). Two health behaviors emerged as mediators in the overall sample: BMI and exercise. These findings suggest that PEWB factors such as positive affect and life satisfaction are associated with HbA1c in both the general population and older, chronically ill individuals. Health factors such as BMI and moderate exercise mediate this relationship.

研究血糖控制指标HbA1c与积极情绪健康(PEWB)之间的关系。数据来自一项全国性调查(N = 1933),其中包括老年慢性疾病亚组(N = 905)。PEWB的两个方面通过横断面回归分析进行评估,分别从积极影响和生活满意度预测HbA1c,控制人口变量。通过手指刺血点分析HbA1c。健康行为(吸烟、饮酒、身体质量指数和适度运动)的中介作用也被检查。较高的积极情绪和生活满意度与总体、老年、慢性病样本中的较低HbA1c、人口统计学控制以及健康行为和抑郁显著相关。总体样本中,积极情绪较低和生活满意度较低的个体临床HbA1c升高(bbb6.5)的几率增加,这表明患有糖尿病(OR = 1.37;(OR = 1.13)和老年慢性病患者(OR = 1.59;OR = 1.14)。在整个样本中,有两种健康行为起到了中介作用:BMI和锻炼。这些发现表明,PEWB因素,如积极影响和生活满意度,与普通人群和老年慢性病患者的HbA1c有关。身体质量指数和适度运动等健康因素介导了这种关系。
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引用次数: 0
Psychological flexibility as a mechanism of change in online ACT among adults living with chronic health conditions. 心理灵活性作为慢性疾病成人在线ACT变化的机制
IF 2.9 3区 医学 Q2 PSYCHOLOGY, CLINICAL Pub Date : 2025-10-01 Epub Date: 2025-07-16 DOI: 10.1007/s10865-025-00585-8
Francesca M Knudsen, Marissa L Donahue, Korena S Klimczak, Ty B Aller, Michael E Levin

Living with a chronic health condition (CHC) can negatively impact quality of life (QoL) through a complex interaction of mental health challenges, functional limitations, and disease management demands. Acceptance and Commitment Therapy (ACT) is a transdiagnostic approach that shows promise in addressing shared challenges across various CHCs by fostering psychological flexibility (PF). PF has been associated with improved QoL and functional outcomes and reduced psychological symptoms in individuals living with specific CHCs; yet its mediating role in these outcomes remains underexplored. This secondary analysis examined whether changes in PF mediated improvements in QoL, psychological symptoms, and functional impairment among individuals with various CHCs. Participants (n = 100) were randomized to a six-session self-guided, online ACT program or a waitlist control group. Outcomes were assessed at baseline, post-treatment, and four-week follow-up. Results revealed that increases in PF significantly mediated improvements in QoL, with indirect effects indicating that higher PF at post-treatment predicted better QoL at follow-up. The ACT group demonstrated significant reductions in functional impairment at follow-up compared to the waitlist group, though this effect was not mediated by changes in PF. Improvements in psychological symptoms were not statistically significant and were not mediated by PF. These findings suggest that ACT effectively enhances PF, which subsequently improves QoL in individuals with CHCs. This supports the transdiagnostic applicability of ACT for improving mental health and QoL across diverse chronic conditions. Future research should explore additional mechanisms underlying ACT's effects and investigate ways to optimize its impact on functional and psychological outcomes within CHCs.

慢性健康状况(CHC)会通过心理健康挑战、功能限制和疾病管理需求的复杂相互作用对生活质量(QoL)产生负面影响。接受和承诺治疗(ACT)是一种跨诊断方法,通过培养心理灵活性(PF),有望解决各种CHCs面临的共同挑战。在患有特定CHCs的个体中,PF与改善生活质量和功能结局以及减少心理症状相关;然而,它在这些结果中的中介作用仍未得到充分探索。这项二级分析检查了不同CHCs患者中PF的改变是否介导了生活质量、心理症状和功能障碍的改善。参与者(n = 100)被随机分配到一个六次自我指导的在线ACT项目或一个等候名单对照组。在基线、治疗后和四周随访时评估结果。结果显示,PF的增加显著介导了生活质量的改善,间接效应表明,治疗后较高的PF预示着随访时更好的生活质量。与等候名单组相比,ACT组在随访中显示出功能损害的显著减少,尽管这种效果不是由PF的变化介导的,心理症状的改善没有统计学意义,也不是由PF介导的,这些发现表明ACT有效地增强了PF,从而改善了CHCs患者的生活质量。这支持ACT的跨诊断适用性,以改善不同慢性疾病的心理健康和生活质量。未来的研究应该探索ACT作用的其他机制,并研究如何优化其对CHCs功能和心理结果的影响。
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引用次数: 0
Associations between self-reported and actigraphy measured sleep duration with metabolic syndrome: evidence from NHANES 2011-2014. 自我报告和活动记录仪测量的睡眠时间与代谢综合征之间的关联:来自NHANES 2011-2014的证据。
IF 2.9 3区 医学 Q2 PSYCHOLOGY, CLINICAL Pub Date : 2025-10-01 Epub Date: 2025-08-19 DOI: 10.1007/s10865-025-00593-8
Isamar M Almeida, Renee Kessler, Gabrielle Murillo, Danica C Slavish

We used a nationally representative dataset to examine the associations between self-reported and actigraphy-measured sleep duration and a continuous metabolic syndrome (MetS) severity score in the United States population. We analyzed cross-sectional data from the national and nutrition examination survey (NHANES) 2011-2014 cycles. Our sample included adults (≥ 20 years) with complete data on sleep, sociodemographic, and MetS-related variables (N = 3245). A composite MetS severity score (MetSSS) was created using measures of waist circumference, fasting glucose, blood pressure, HDL cholesterol, and triglycerides. Actigraphy-measured sleep duration was obtained from accelerometer data collected across 7 days. Self-reported sleep duration was obtained using a one-time single question. The association between sleep duration and MetSSS was examined using linear regression models adjusting for relevant confounders. Self-reported short sleep duration (but not long), and actigraphy-measured long sleep duration (but not short) predicted greater MetSSS (b = 0.21, p < .001 and b = 0.33, p < .001, respectively), when adjusting for sociodemographic factors (age, sex, race/ethnicity, education, income, food insecurity, and health insurance status). However, after covarying for depression, sedentary behavior, sleep disturbances, and diet, only actigraphy measured long sleep duration remained significantly associated with MetS. Both short and long sleep duration may increase the severity of metabolic syndrome. However, the association between short sleep duration and metabolic syndrome may be confounded by other variables (e.g., health behaviors, sleep quality, mood). Research and clinical implications of these results are discussed.

我们使用一个具有全国代表性的数据集来研究美国人群中自我报告和活动记录仪测量的睡眠持续时间与持续代谢综合征(MetS)严重程度评分之间的关系。我们分析了2011-2014年国家和营养检查调查(NHANES)周期的横断面数据。我们的样本包括成年人(≥20岁),具有完整的睡眠、社会人口学和mets相关变量数据(N = 3245)。通过测量腰围、空腹血糖、血压、高密度脂蛋白胆固醇和甘油三酯,建立了代谢代谢严重程度综合评分(MetSSS)。活动记录仪测量的睡眠时间是从7天内收集的加速度计数据中获得的。自我报告的睡眠时间是通过一次性的单一问题获得的。使用线性回归模型对相关混杂因素进行校正,检验睡眠时间与MetSSS之间的关系。自我报告的短睡眠时间(但不长)和活动记录仪测量的长睡眠时间(但不短)预测更高的MetSSS (b = 0.21, p
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引用次数: 0
Within-person, prospective relations between sleep duration and efficiency and next-day physical activity among behavioral weight loss participants. 在个人内部,在行为减肥参与者中,睡眠时间和效率与第二天的身体活动之间的潜在关系。
IF 2.9 3区 医学 Q2 PSYCHOLOGY, CLINICAL Pub Date : 2025-10-01 Epub Date: 2025-07-18 DOI: 10.1007/s10865-025-00581-y
Rebecca J Crochiere, Avery G Freund, Zhuoran Huang, Jaclyn P Maher, Evan M Forman

Objective: Behavioral weight loss programs (BWL) prescribe moderate-to-vigorous physical activity (MVPA) to promote weight control and overall health. However, adherence to the MVPA prescription is low. One factor that may be associated with poor MVPA adherence, both theoretically and as demonstrated by between-subject studies, is suboptimal sleep. Nevertheless, no study to date has examined the within-subject relations between sleep and MVPA among BWL participants, which could better account for between-subject third variables that may confound the relation between sleep and MVPA (e.g., socioeconomic status). This secondary analysis is the first to investigate the within-subject, prospective relations between sleep duration (controlling for time in bed) and sleep quality (operationalized as sleep efficiency, approximately minutes asleep divided by time in bed) with next-day MVPA among BWL participants.

Method: Participants (N = 104) were adults with overweight/obesity engaging in a year-long BWL program. Sleep variables and MVPA bouts were measured using accelerometers at mid-treatment. Predictor variables were standardized, and analyses were conducted using multilevel models, controlling for weekday/weekend status, condition, gender, and body mass index (BMI).

Results: Results indicated within-subject sleep duration (b = 15.48, SE = 6.30, p =.014), but not sleep efficiency (b = 2.16, SE = 1.22, p =.08), was positively associated with next-day minutes of MVPA.

Conclusion: Findings may support modifications of BWL programs to include sleep hygiene education or strategies from cognitive behavioral therapy for insomnia to target sleep duration, which in turn may improve MVPA engagement.

目的:行为减肥计划(BWL)规定适度到剧烈的身体活动(MVPA)来促进体重控制和整体健康。然而,MVPA处方的依从性很低。一个可能与较差的MVPA依从性相关的因素,无论是理论上还是被受试者之间的研究证明,都是次优睡眠。然而,迄今为止还没有研究调查了BWL参与者中睡眠和MVPA之间的受试者内部关系,这可以更好地解释可能混淆睡眠和MVPA之间关系的受试者之间的第三个变量(例如社会经济地位)。这项二级分析首次调查了受试者内部,睡眠持续时间(控制在床上的时间)和睡眠质量(以睡眠效率运作,大约睡眠分钟除以在床上的时间)与BWL参与者第二天MVPA之间的前瞻性关系。方法:参与者(N = 104)是超重/肥胖的成年人,参加了为期一年的BWL计划。在治疗中期使用加速度计测量睡眠变量和MVPA发作。对预测变量进行标准化,并使用多层模型进行分析,控制工作日/周末状态、状况、性别和体重指数(BMI)。结果:受试者内睡眠时间(b = 15.48, SE = 6.30, p = 0.014)与次日MVPA分钟数呈正相关,而睡眠效率(b = 2.16, SE = 1.22, p = 0.08)与次日MVPA分钟数呈正相关。结论:研究结果可能支持调整睡眠习惯计划,包括睡眠卫生教育或从失眠的认知行为治疗策略到目标睡眠时间,进而可能提高MVPA的参与。
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引用次数: 0
Engagement in and correlates of total cutaneous exams and skin self-exams among young melanoma survivors and their family. 年轻黑色素瘤幸存者及其家人参与全面皮肤检查和皮肤自我检查及其相关性
IF 2.9 3区 医学 Q2 PSYCHOLOGY, CLINICAL Pub Date : 2025-10-01 Epub Date: 2025-07-20 DOI: 10.1007/s10865-025-00589-4
Sharon L Manne, Deborah A Kashy, Sherry Pagoto, Susan K Peterson, Carolyn J Heckman, Joseph Gallo, Adam Berger, David B Buller, Alexandria Kulik, Sara Frederick, Morgan Pesanelli

Young adult melanoma survivors and their close family (first degree relatives/FDRs) are at increased risk for developing a melanoma, but little is known about engagement in and correlates of their clinical skin exam (CSE) and skin self-examination (SSE) behaviors. Five hundred and seventy-four YA survivors and their FDRs completed an online survey assessing engagement in CSE and SSE, as well as measures of background factors, cognitive and psychosocial factors, CSE and SSE planning, and family influences. Approximately 90% of YAs had a CSE and 90% performed SSE in the last year, but engagement in CSE among FDRs was lower (63.2%, CSE; 64.9%, SSE). For CSE, females, a physician recommendation, fewer barriers, and more planning were associated with CSE. Family influences were not associated with CSE. For SSE, a physician recommendation and greater self-efficacy were associated with engagement, and more comprehensive SSE was associated with a physician recommendation, lower education, greater self-efficacy, and more planning. Stronger family normative influences were associated with more comprehensive SSEs among males. Findings suggest FDRs may benefit from interventions to improve CSE and SSE and indicate that physician recommendation may be a key intervention target to foster CSE and SSE.

年轻成年黑色素瘤幸存者及其近亲(一级亲属/FDRs)患黑色素瘤的风险增加,但对其临床皮肤检查(CSE)和皮肤自检(SSE)行为的参与及其相关性知之甚少。574名YA幸存者和他们的fdr完成了一项在线调查,评估了CSE和SSE的参与程度,以及背景因素、认知和社会心理因素、CSE和SSE计划和家庭影响的测量。在去年,大约90%的私募股权投资公司有CSE, 90%的私募股权投资公司执行了SSE,但私募股权投资公司参与CSE的比例较低(63.2%,CSE;64.9%, SSE)。对于CSE,女性,医生建议,较少的障碍和更多的计划与CSE相关。家庭影响与CSE无关。对于SSE,医生推荐和更高的自我效能感与敬业度相关,而更全面的SSE与医生推荐、更低的教育程度、更高的自我效能感和更多的计划相关。在男性中,更强的家庭规范影响与更全面的社会行为相关。研究结果表明,fdr可能受益于改善CSE和SSE的干预措施,并表明医生推荐可能是促进CSE和SSE的关键干预目标。
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引用次数: 0
Representing subpopulations with latent profile analysis: a non-technical introduction using exercisers' goal orientation adoption profiles. 用潜在剖面分析代表亚群体:使用锻炼者的目标取向采用剖面的非技术介绍。
IF 2.9 3区 医学 Q2 PSYCHOLOGY, CLINICAL Pub Date : 2025-09-09 DOI: 10.1007/s10865-025-00596-5
E Whitney G Moore, Alessandro Quartiroli

Latent profile analysis (LPA) is in the finite mixture model analysis family and identifies subgroups by participants' responses to continuous variables (i.e., indicators); participants' probable membership in each subgroup is based on the similarity between the subgroup's prototypical responses and the person's unique responses. Compared to latent class analysis (LCA) with categorical data, LPA is a better fit for many variables and theories in behavioral medicine, because LPA can have continuous item, sub-scale, or scale scores as indicators, which can enable identifying and examining subgroups defined by responses representing complex, multidimensional concepts (e.g., orientations, motivations, well-being, ill-being, physical activity engagement) and biomarkers of diseases and disorders. Recently, the use of LPA has increased and as it continues to evolve, it is important researchers know best practice recommendations and explanations for both conducting as well as reading/reviewing LPA models. With this paper we: 1) discuss the strengths and weaknesses of LPA and the questions it is most appropriate to answer, 2) introduce LPA conceptually, 3) illustrate an LPA conducted with exercise psychology variables following current best practice recommendations, and 4) juxtapose resulting models from the LPA approach to a typical approach with the same data. We also share the data and syntax files used to conduct the basic steps of the LPA analyses as supplemental appendix files in addition to including the tables and figures for reporting LPA results following best practices.

潜在剖面分析(LPA)属于有限混合模型分析家族,通过参与者对连续变量(即指标)的反应来识别亚组;参与者在每个子组中的可能成员身份是基于子组原型反应和个人独特反应之间的相似性。与使用分类数据的潜类分析(LCA)相比,LPA更适合行为医学中的许多变量和理论,因为LPA可以将连续的项目、子量表或量表得分作为指标,这可以识别和检查由代表复杂、多维概念(例如,取向、动机、幸福感、不健康、身体活动参与)和疾病和障碍的生物标志物的反应定义的亚组。最近,LPA的使用有所增加,随着它的不断发展,重要的是研究人员知道最佳实践建议和解释,以指导和阅读/审查LPA模型。在本文中,我们:1)讨论了LPA的优缺点以及最适合回答的问题;2)从概念上介绍了LPA; 3)根据当前的最佳实践建议,说明了一个使用运动心理学变量进行的LPA; 4)将LPA方法的结果模型与具有相同数据的典型方法并列。我们还将用于执行LPA分析的基本步骤的数据和语法文件作为补充附录文件共享,此外还包括用于按照最佳实践报告LPA结果的表和图。
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引用次数: 0
Determining the power of a 1-sided z-test given only the power of the corresponding 2-sided test. 仅在给定相应的双侧检验的幂的情况下确定单侧z检验的幂。
IF 2.9 3区 医学 Q2 PSYCHOLOGY, CLINICAL Pub Date : 2025-09-09 DOI: 10.1007/s10865-025-00595-6
Amy Liang, Kristopher J Preacher, Nathaniel J Williams, Paul D Allison, Steven C Marcus, Sonya K Sterba

Estimating statistical power is essential for designing behavioral medicine studies efficiently and conserving finite resources. Sometimes behavioral medicine researchers are interested in calculating power for 1-sided z-tests of individual parameters (e.g., slopes) in complex models such as multilevel structural equation models or multilevel mixture regression models. For such models, calculating power for 1-sided z-tests is cumbersome because: (a) online z-test power calculator tools are inapplicable, (b) commonly-used power analysis software provides power only for 2-sided z-tests and does not allow changing alpha, and (c) published power tables typically provide power results only for 2-sided z-tests. Hence, here we introduce straightforward and resource-efficient conversion formulas to estimate the power of 1-sided z-tests of individual parameters in any model by using direct power conversions from the corresponding 2-sided tests. We then implement these conversion formulas in accessible R and Excel software. This brief report thus provides behavioral medicine researchers with a convenient and practical solution for power calculation that minimizes the time, financial, and computational resources typically needed for power estimation.

估计统计能力是有效设计行为医学研究和节约有限资源的必要条件。有时,行为医学研究人员对多层结构方程模型或多层混合回归模型等复杂模型中单个参数(如斜率)的单侧z检验的计算能力感兴趣。对于这样的模型,计算单侧z检验的功率是很麻烦的,因为:(a)在线z检验功率计算器工具不适用,(b)常用的功率分析软件只提供双侧z检验的功率,不允许改变alpha, (c)出版的功率表通常只提供双侧z检验的功率结果。因此,在这里,我们引入了简单和资源高效的转换公式,通过使用相应的双侧检验的直接功率转换来估计任何模型中单个参数的单侧z检验的功率。然后我们在可访问的R和Excel软件中实现这些转换公式。因此,这篇简短的报告为行为医学研究人员提供了一种方便实用的功率计算解决方案,最大限度地减少了功率估计通常所需的时间、财务和计算资源。
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引用次数: 0
Methods for analyzing longitudinal data from randomized pretest-posttest-follow-up trials in behavioral research: a practical guide to latent change models. 行为研究中随机前测后测随访试验纵向数据分析方法:潜在变化模型的实用指南。
IF 2.9 3区 医学 Q2 PSYCHOLOGY, CLINICAL Pub Date : 2025-09-09 DOI: 10.1007/s10865-025-00600-y
Constance A Mara

Randomized pretest, posttest, follow-up (RPPF) designs are widely used in longitudinal behavioral intervention research to evaluate the efficacy of treatments over time. These designs typically involve random assignment of participants to treatment and control conditions, with assessments conducted at baseline, immediately post-intervention, and during the follow-up period. Researchers primarily focus on determining whether the intervention is more effective than the control condition at post-treatment and whether these effects are sustained or change over time. This paper presents Latent Change Models (LCMs) as a practical approach for analyzing randomized pretest-posttest-follow-up (RPPF) trials, directly estimating discrete changes between timepoints and intervention-control group differences. The utility of LCMs is demonstrated through an application to the STAR (Supporting Treatment Adherence Regimens) trial, a pediatric randomized behavioral clinical trial aimed at improving adherence to anti-seizure medications (ASMs) among children with new-onset epilepsy. The results of the trial analyzed via an LCM are contrasted with the results as analyzed by an ANCOVA, a longitudinal linear mixed-effects model, and a latent growth curve model. The tutorial and application to the STAR trial demonstrate that LCMs offer notable strengths, including the ability to estimate discrete changes over time, control for baseline variability in the outcome, and incorporate all longitudinal data within a single, parsimonious model. These models provide an accurate and nuanced understanding of intervention effects in RPPF designs, with implications for clinical intervention research.

随机前测、后测、随访(RPPF)设计被广泛应用于纵向行为干预研究,以评估治疗的长期疗效。这些设计通常包括将参与者随机分配到治疗和控制条件,并在基线、干预后立即和随访期间进行评估。研究人员主要关注的是在治疗后确定干预是否比对照条件更有效,以及这些影响是否持续或随着时间的推移而改变。本文提出了潜在变化模型(lcm)作为分析随机前测后测随访(RPPF)试验的实用方法,直接估计时间点之间的离散变化和干预对照组的差异。lcm的效用通过STAR(支持治疗依从性方案)试验的应用得到了证明,STAR是一项儿科随机行为临床试验,旨在提高新发癫痫儿童抗癫痫药物(asm)的依从性。通过LCM分析的试验结果与ANCOVA、纵向线性混合效应模型和潜在生长曲线模型分析的结果进行了对比。STAR试验的教程和应用表明,lcm具有显著的优势,包括能够估计随时间的离散变化,控制结果的基线可变性,并将所有纵向数据合并到一个简单的模型中。这些模型对RPPF设计中的干预效果提供了准确而细致的理解,对临床干预研究具有指导意义。
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Journal of Behavioral Medicine
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