Pub Date : 2024-04-01DOI: 10.1016/j.jaccao.2024.02.001
Dina Ioffe MD , Sanjana C. Bhatia-Patel DO , Sakshi Gandhi MD , Eman A. Hamad MD , Efrat Dotan MD
Cardiovascular disease (CVD) and cancer are leading causes of death globally, particularly among the rapidly growing population of older adults (OAs). CVD is a leading cause of mortality among cancer survivors, often accelerated by cancer treatments associated with short- or long-term cardiotoxicity. Moreover, there is a dynamic relationship among CVD, cancer, and aging, characterized by shared risk factors and biological hallmarks, that plays an important role in caring for OAs, optimizing treatment approaches, and developing preventive strategies. Assessment of geriatric domains (eg, functional status, comorbidities, cognition, polypharmacy, nutritional status, social support, psychological well-being) is critical to individualizing treatment of OAs with cancer. The authors discuss considerations in caring for an aging population with cancer, including methods for the assessment of OAs with CVD and/or cardiovascular risk factors planned for cancer therapy. Multidisciplinary care is critical in optimizing patient outcomes and maintaining quality of life in this growing vulnerable population.
{"title":"Cardiovascular Concerns, Cancer Treatment, and Biological and Chronological Aging in Cancer","authors":"Dina Ioffe MD , Sanjana C. Bhatia-Patel DO , Sakshi Gandhi MD , Eman A. Hamad MD , Efrat Dotan MD","doi":"10.1016/j.jaccao.2024.02.001","DOIUrl":"https://doi.org/10.1016/j.jaccao.2024.02.001","url":null,"abstract":"<div><p>Cardiovascular disease (CVD) and cancer are leading causes of death globally, particularly among the rapidly growing population of older adults (OAs). CVD is a leading cause of mortality among cancer survivors, often accelerated by cancer treatments associated with short- or long-term cardiotoxicity. Moreover, there is a dynamic relationship among CVD, cancer, and aging, characterized by shared risk factors and biological hallmarks, that plays an important role in caring for OAs, optimizing treatment approaches, and developing preventive strategies. Assessment of geriatric domains (eg, functional status, comorbidities, cognition, polypharmacy, nutritional status, social support, psychological well-being) is critical to individualizing treatment of OAs with cancer. The authors discuss considerations in caring for an aging population with cancer, including methods for the assessment of OAs with CVD and/or cardiovascular risk factors planned for cancer therapy. Multidisciplinary care is critical in optimizing patient outcomes and maintaining quality of life in this growing vulnerable population.</p></div>","PeriodicalId":48499,"journal":{"name":"Jacc: Cardiooncology","volume":"6 2","pages":"Pages 143-158"},"PeriodicalIF":11.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666087324000541/pdfft?md5=f6fde9a1b8f8c024d4e684b8807473fc&pid=1-s2.0-S2666087324000541-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140559159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-01DOI: 10.1016/j.jaccao.2024.03.002
Joshua P. Barrios PhD , Madhav R. Seshadri MD , Geoffrey H. Tison MD, MPH
{"title":"Artificial Intelligence to Complement, Not Replace, Clinical Knowledge","authors":"Joshua P. Barrios PhD , Madhav R. Seshadri MD , Geoffrey H. Tison MD, MPH","doi":"10.1016/j.jaccao.2024.03.002","DOIUrl":"https://doi.org/10.1016/j.jaccao.2024.03.002","url":null,"abstract":"","PeriodicalId":48499,"journal":{"name":"Jacc: Cardiooncology","volume":"6 2","pages":"Pages 264-266"},"PeriodicalIF":11.1,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666087324000632/pdfft?md5=4cd9385a89968fa93c891c0ef922440a&pid=1-s2.0-S2666087324000632-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140559124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01DOI: 10.1016/j.jaccao.2023.12.004
Richard Von Itter BA , Kathryn J. Moore PhD
{"title":"Cross-Disease Communication in Cardiovascular Disease and Cancer∗","authors":"Richard Von Itter BA , Kathryn J. Moore PhD","doi":"10.1016/j.jaccao.2023.12.004","DOIUrl":"https://doi.org/10.1016/j.jaccao.2023.12.004","url":null,"abstract":"","PeriodicalId":48499,"journal":{"name":"Jacc: Cardiooncology","volume":"6 1","pages":"Pages 67-70"},"PeriodicalIF":11.1,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666087324000024/pdfft?md5=9e4aac0ee7ae024776dec474fe852e9d&pid=1-s2.0-S2666087324000024-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139915509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01DOI: 10.1016/j.jaccao.2023.12.001
Tzu-Fei Wang MD, MPH , Jean M. Connors MD
{"title":"The Pursuit of “Best” Anticoagulant for Cancer-Associated Thrombosis","authors":"Tzu-Fei Wang MD, MPH , Jean M. Connors MD","doi":"10.1016/j.jaccao.2023.12.001","DOIUrl":"10.1016/j.jaccao.2023.12.001","url":null,"abstract":"","PeriodicalId":48499,"journal":{"name":"Jacc: Cardiooncology","volume":"6 1","pages":"Pages 114-116"},"PeriodicalIF":11.1,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666087323003551/pdfft?md5=0f3024ead28f3d16baf38f52469ec6e5&pid=1-s2.0-S2666087323003551-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139456779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-01DOI: 10.1016/j.jaccao.2023.12.008
Rawan A. Hammoud MD , Daniel A. Mulrooney MD, MS , Isaac B. Rhea MD , Christine Yu MD , Jason N. Johnson MD, MHSc , Eric J. Chow MD, MPH , Matthew J. Ehrhardt MD, MS , Melissa M. Hudson MD , Kirsten K. Ness PhD , Gregory T. Armstrong MD, MSCE , Stephanie B. Dixon MD, MPH
The growing community of childhood cancer survivors faces a heavy burden of late onset morbidities and mortality, with cardiovascular diseases being the leading noncancer cause. In addition to demographics and cancer treatment exposures, which cannot be altered, cardiometabolic risk factors (obesity, hypertension, diabetes, and dyslipidemia) and frailty potentiate the risk of morbidity and mortality associated with chronic health conditions. Important opportunities exist to target these risk factors and improve late health outcomes for survivors. Unfortunately, limited evidence exists on the optimal methods to prevent, screen, and treat cardiometabolic risk factors among survivors, resulting in significant underdiagnosis and undertreatment. In this review, we discuss the prevalence of, risk factors for, current survivor-specific recommendations, and gaps in knowledge to mitigate potentially modifiable cardiometabolic risk factors and frailty among survivors of childhood cancer.
{"title":"Modifiable Cardiometabolic Risk Factors in Survivors of Childhood Cancer","authors":"Rawan A. Hammoud MD , Daniel A. Mulrooney MD, MS , Isaac B. Rhea MD , Christine Yu MD , Jason N. Johnson MD, MHSc , Eric J. Chow MD, MPH , Matthew J. Ehrhardt MD, MS , Melissa M. Hudson MD , Kirsten K. Ness PhD , Gregory T. Armstrong MD, MSCE , Stephanie B. Dixon MD, MPH","doi":"10.1016/j.jaccao.2023.12.008","DOIUrl":"https://doi.org/10.1016/j.jaccao.2023.12.008","url":null,"abstract":"<div><p>The growing community of childhood cancer survivors faces a heavy burden of late onset morbidities and mortality, with cardiovascular diseases being the leading noncancer cause. In addition to demographics and cancer treatment exposures, which cannot be altered, cardiometabolic risk factors (obesity, hypertension, diabetes, and dyslipidemia) and frailty potentiate the risk of morbidity and mortality associated with chronic health conditions. Important opportunities exist to target these risk factors and improve late health outcomes for survivors. Unfortunately, limited evidence exists on the optimal methods to prevent, screen, and treat cardiometabolic risk factors among survivors, resulting in significant underdiagnosis and undertreatment. In this review, we discuss the prevalence of, risk factors for, current survivor-specific recommendations, and gaps in knowledge to mitigate potentially modifiable cardiometabolic risk factors and frailty among survivors of childhood cancer.</p></div>","PeriodicalId":48499,"journal":{"name":"Jacc: Cardiooncology","volume":"6 1","pages":"Pages 16-32"},"PeriodicalIF":11.1,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666087324000085/pdfft?md5=76782cd2929183fd9403582f5787a94d&pid=1-s2.0-S2666087324000085-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139915507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号