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Borderline Personality Disorder and Emotion Dysregulation最新文献

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BDSM and masochistic sexual fantasies in women with borderline personality disorder: simply on the spectrum of "normality" or source of suffering? 边缘型人格障碍女性的BDSM和受虐性幻想:仅仅是在“正常”的范围内还是痛苦的来源?
IF 2.7 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-02-22 DOI: 10.1186/s40479-025-00283-6
Hannah F Warkentin, Rose Gholami Mazinan, Johannes Fuss, Leonhard Kratzer, Sarah V Biedermann

Background: Increasing research has contributed to the destigmatization of sadomasochistic sexual preferences. Nevertheless, persons diagnosed with Borderline Personality Disorder (BPD) frequently report self-harmful masochistic sexual practice under the pretext of BDSM, especially those reporting experiences of child sexual abuse (CSA). Empirical research on sexual preferences in the context of BPD is scarce, although related sexual behaviors may matter particularly regarding dysfunctional and self-harming behaviors.

Methods: Women with BPD (n = 115) and age-matched healthy controls (HC; n = 115) were compared regarding experiences with BDSM and masochistic fantasies, as well as associated arousal and distress. Regression and moderation analyses were conducted on cross-sectional data to examine the associations between sadomasochistic sexuality and BPD symptoms, traumatic experiences, sexual risk behavior, and sexual motivation.

Results: Women with BPD practiced BDSM more often (last year: 34% vs. 15%; lifetime: 51% vs. 23%) which was associated with more autonomous, self-determined forms of sexual motivation but at the same time associated with higher BPD symptoms and risky sexuality. While a similar number of women in both groups endorsed arousal through masochistic sexual fantasies (77% vs. 74%), significantly more of those women with BPD reported associated marked distress (53% vs. 21%). Distress from masochistic fantasies was associated with less autonomous sexual motivation, in which sexuality is used in order to regulate emotions and self-esteem, and was predicted by the interaction of the severity of childhood sexual abuse and this regulation tendency.

Conclusion: Sadomasochistic sexuality and corresponding fantasies in women can be an autonomous, self-determined form of sexuality. However, in women with BPD they tend to be associated with BPD symptoms, risky sexuality, problems with self-regulation and traumatization and are thus associated with marked distress. Our findings highlight the importance of considering sexual preferences in clinical context and the need for specific treatment for this subgroup suffering from their preference or acting them out in a dysfunctional or self-harming way.

Trial registration: This analysis is part of a larger ongoing study and was retrospectively registered (Registration trial DRKS00029716).

背景:越来越多的研究有助于消除施虐受虐性取向的污名化。然而,被诊断为边缘型人格障碍(BPD)的人经常以BDSM为借口报告自我伤害的受虐性行为,特别是那些报告儿童性虐待(CSA)经历的人。尽管相关的性行为可能与功能障碍和自我伤害行为特别相关,但关于BPD背景下性偏好的实证研究很少。方法:BPD女性(n = 115)和年龄匹配的健康对照(HC;n = 115)比较了BDSM和受虐幻想的经历,以及相关的觉醒和痛苦。对横断面数据进行回归和适度分析,以检验施虐受虐性行为与BPD症状、创伤经历、性风险行为和性动机之间的关系。结果:患有BPD的女性更常使用BDSM(去年:34% vs. 15%;终生:51%对23%),这与更自主、自我决定的性动机形式有关,但同时与更高的BPD症状和高风险的性行为有关。虽然两组中有相似数量的女性通过受虐性幻想来唤起性欲(77%对74%),但明显更多的BPD女性报告有明显的痛苦(53%对21%)。受虐幻想带来的痛苦与较不自主的性动机有关,在这种情况下,性行为是用来调节情绪和自尊的,并且可以通过童年性虐待的严重程度和这种调节倾向的相互作用来预测。结论:女性的施虐受虐性和相应的性幻想可能是一种自主的、自我决定的性形式。然而,在患有BPD的女性中,它们往往与BPD症状、危险性行为、自我调节问题和创伤有关,因此与明显的痛苦有关。我们的研究结果强调了在临床环境中考虑性偏好的重要性,以及对遭受性偏好或以功能失调或自我伤害的方式表现出来的亚群进行特定治疗的必要性。试验注册:该分析是一项更大的正在进行的研究的一部分,回顾性注册(注册试验DRKS00029716)。
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引用次数: 0
AIR therapy: a pilot study of a clinician-assisted e-therapy for adolescents with borderline personality disorder. 空气疗法:临床辅助电子治疗青少年边缘型人格障碍的初步研究。
IF 4 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-02-11 DOI: 10.1186/s40479-025-00281-8
B F S Grenyer, N J S Day, G Denmeade, A Ciarla, K Davy, S Reis, M Townsend

Background: While the majority of personality disorder research focuses on adults, research shows that borderline personality disorder (BPD) often emerges in adolescence, highlighting the importance of early intervention for this population. Despite this, there are limited intervention programs tailored specifically for adolescents with BPD, and no research has explored the effectiveness of online therapist-assisted interventions for BPD in adolescents. As such, this pilot study aimed to address this gap in the literature by exploring the effectiveness of a therapist-assisted online intervention (AIR Therapy) with adolescents with BPD.

Method: The intervention involved 6 online weekly learning modules in conjunction with a weekly telehealth consultation session with a clinician. Modules included: introduction to AIR therapy, mindfulness and managing distress, emotions, self and identity, our interpersonal skills, and self-care. Participants were 12 adolescents (83.3% female, M age = 15 years) and 12 clinicians (100% female, M age = 34.3 years) recruited naturalistically from publicly funded mental health services located in rural and remote locations. Adolescents were compared on BPD symptom severity, mental health symptoms and quality of life at baseline and follow-up. Measures and semi-structured interviews were also completed evaluating the effectiveness and acceptability of the intervention at follow-up.

Results: Both adolescents and clinicians rated the intervention positively in terms of its effectiveness and acceptability. Paired-sample t-tests showed significant improvement in BPD symptoms, mental health and health satisfaction from intake to end of therapy. Adolescents' qualitative responses revealed themes of improving self-regulation and coping, ease of the online workbook, and the value of clinician interaction. Additionally, clinicians' responses highlighted themes of adding structure to therapy, the value of a brief intervention, enhancing self-insight and helping adolescents build skills that they can utilise in everyday life. Both adolescents and clinicians also highlighted suggested areas for improvement.

Conclusion: The structured online therapist-assisted intervention in the early treatment of BPD was acceptable and helpful for participants and their clinicians in this rural and remote real-world setting. This intervention may also be particularly suited for newer or trainee clinicians, providing structured tools for use with a challenging population.

背景:虽然大多数人格障碍的研究都集中在成年人身上,但研究表明边缘型人格障碍(BPD)经常出现在青春期,这突出了早期干预对这一人群的重要性。尽管如此,专门为青少年BPD量身定制的干预计划有限,并且没有研究探索在线治疗师辅助干预青少年BPD的有效性。因此,本试点研究旨在通过探索治疗师辅助在线干预(AIR疗法)对青少年BPD的有效性来解决文献中的这一空白。方法:干预包括6个在线每周学习模块,结合每周一次与临床医生的远程医疗会诊。课程内容包括:空气疗法导论、正念和管理痛苦、情绪、自我和身份、人际交往技巧和自我护理。参与者为12名青少年(83.3%为女性,年龄= 15岁)和12名临床医生(100%为女性,年龄= 34.3岁),从农村和偏远地区的公共资助精神卫生服务机构自然招募。在基线和随访时比较青少年BPD症状严重程度、心理健康症状和生活质量。还完成了测量和半结构化访谈,以评估随访时干预措施的有效性和可接受性。结果:青少年和临床医生对干预的有效性和可接受性均给予积极评价。配对样本t检验显示,从治疗开始到治疗结束,BPD症状、心理健康和健康满意度均有显著改善。青少年的定性反应揭示了改善自我调节和应对的主题,在线工作手册的便利性,以及临床医生互动的价值。此外,临床医生的回答强调了增加治疗结构、短暂干预的价值、增强自我洞察力和帮助青少年建立他们可以在日常生活中使用的技能等主题。青少年和临床医生也强调了建议的改进领域。结论:在农村和偏远的现实世界环境中,结构化的在线治疗师辅助干预在BPD的早期治疗中是可接受的,并且对参与者及其临床医生有帮助。这种干预也可能特别适合新手或实习临床医生,为具有挑战性的人群提供结构化的工具。
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引用次数: 0
How mothers with severe emotion dysregulation use DBT skills in parenting contexts: observational coding of skills use in a DBT skills training group. 有严重情绪失调的母亲如何在育儿环境中使用DBT技能:DBT技能训练组中技能使用的观察编码。
IF 4 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-02-04 DOI: 10.1186/s40479-025-00279-2
Yoel Everett, Olivia A Frigoletto, Jacqueline R O'Brien, Amy L Byrd, Stephanie D Stepp, Maureen Zalewski

Background: Dialectical Behavior Therapy's (DBT) well established effectiveness in reducing emotion dysregulation, and the growing recognition that parental emotion regulation is critical to effective parenting has led to increasing interest in the applicability of DBT skills to parenting. Efforts to integrate DBT and parenting interventions would benefit from an empirical examination of which DBT skills are most useful to parents with emotion dysregulation.

Methods: This study used clinician-rated observational coding of skill use examples that were provided by mothers with severe emotion dysregulation (n = 16) who participated in a standard 48-week DBT Skills Training (DBT-ST) program in the context of a larger randomized controlled trial (NCT03060902). Mothers described their use of DBT skills during the homework review portion of DBT-ST sessions and video-recordings were then examined and coded to identify which DBT skills mothers most frequently described using in parenting situations (vs. non-parenting situations) and which skills were used to either increase positive parenting behaviors or to decrease negative parenting behaviors.

Results: A total of 220 skill use examples were coded and approximately one-quarter described skill use in parenting situations. Mindfulness, Distress Tolerance, and Emotion Regulation skills were the most frequently described skills used in parenting situations, while Interpersonal Effectiveness skills were rarely coded. Mindfulness and Emotion Regulation skills were most often coded when mothers' parenting goal was to increase positive parenting, while Distress Tolerance skills were most often coded when mothers' parenting goal was to decrease negative parenting behaviors.

Conclusions: Results provide an empirical basis which clinicians and treatment developers can use when selecting DBT skills to apply towards parenting challenges.

背景:辩证行为疗法(DBT)在减少情绪失调方面已经建立了良好的效果,并且越来越多的人认识到父母情绪调节对有效育儿至关重要,这导致了对DBT技能在育儿中的适用性的兴趣日益增加。对哪些DBT技能对情绪失调的父母最有用进行实证检验,将DBT与育儿干预相结合的努力将会受益。方法:本研究采用临床评价的观察性技能使用示例编码,这些示例由参加标准的48周DBT技能培训(DBT- st)项目的严重情绪失调母亲(n = 16)提供,该项目在一个更大的随机对照试验(NCT03060902)的背景下进行。母亲在DBT- st课程的家庭作业复习部分描述了她们使用DBT技能的情况,然后对录像进行了检查和编码,以确定母亲在养育子女的情况下(与非养育子女的情况相比)最常使用哪些DBT技能,以及哪些技能用于增加积极的养育行为或减少消极的养育行为。结果:总共有220个技能使用示例被编码,大约四分之一描述了在育儿情况下的技能使用。正念、痛苦容忍和情绪调节技能是在养育子女的情况下最常被描述的技能,而人际关系效率技能则很少被编码。当母亲的育儿目标是增加积极的育儿行为时,正念和情绪调节技能最常被编码,而当母亲的育儿目标是减少消极的育儿行为时,痛苦容忍技能最常被编码。结论:研究结果为临床医生和治疗开发人员在选择DBT技能以应对育儿挑战时提供了经验基础。
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引用次数: 0
Emotion dysregulation in adolescents is normalized by ADHD pharmacological treatment. 青少年情绪失调通过ADHD药物治疗正常化。
IF 4 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-02-03 DOI: 10.1186/s40479-024-00268-x
Krisztina Kondi, Mária Takács, Evelyn Kovács-Posta, Claudia Szajli, Tünde Sebők-Welker, János M Réthelyi, Nóra Bunford

Background: Attention-deficit/hyperactivity disorder (ADHD) is associated with emotion dysregulation (ED) and in ADHD, beyond ADHD and comorbidity severity, ED confers increased risk for negative outcomes. First- and second-line ADHD pharmacotherapy is effective at ameliorating core symptoms and improving cognitive functioning and accumulating evidence indicates primairly in children and adults, active ADHD pharmacotherapy has beneficial effects on emotional symptoms. Gaps in knowledge remain about whether in adolescents, ADHD pharmacotherapy has beneficial effects on ED or about the extent to which effects are apparent for discontinued/ past ADHD pharmacotherapy.

Methods: Examined, in N = 297 adolescents (Mage=15.77 years, SD = 1.06; 39.06% girls; n = 86 classified as with ADHD), whether accounting for depression and oppositional symptoms, concurrent and 18-month prospective measures of parent- and self-reported ED (1) differ across adolescents without ADHD, medication-naïve adolescents with ADHD, and ever-medicated (currently or previously) adolescents with ADHD.

Results: In case of parent-reported ED, ever medicated adolescents with ADHD exhibited a decline in ED over time whereas adolescents without ADHD and never medicated adolescents with ADHD exhibited no changes in ED over time. In case of self-reported ED, ever-medicated adolescents with ADHD exhibited lower ED than never medicated adolescents with ADHD and never medicated adolescents with ADHD exhibited greater ED than adolescents without ADHD. Currently and previously (but not currently) medicated adolescents did not differ in ED. Across parent- and self-reported findings, observed pattern of results held when analyses focused on adolescents who did not change medication status between baseline and follow-up.

Conclusions: ADHD pharmacotherapy may have a boosting effect on longitudinal changes in parent-reported ED and a normalizing effect on concurrent measures of self-reported ED in adolescents.

背景:注意缺陷/多动障碍(ADHD)与情绪调节障碍(ED)有关,在ADHD中,除了ADHD和合并症严重程度之外,ED会增加负面结果的风险。一线和二线ADHD药物治疗在改善核心症状和改善认知功能方面是有效的,越来越多的证据表明,主要在儿童和成人中,积极的ADHD药物治疗对情绪症状有有益的影响。在青少年中,ADHD药物治疗是否对ED有有益的影响,或者在停止/过去的ADHD药物治疗中效果明显的程度,这些知识仍然存在差距。方法:对N = 297名青少年(年龄15.77岁,SD = 1.06;39.06%的女孩;n = 86归类为ADHD),是否考虑抑郁和对立性症状,同时和18个月的父母和自我报告ED的前瞻性测量(1)在没有ADHD的青少年,medication-naïve患有ADHD的青少年和曾经接受过药物治疗的(目前或以前)患有ADHD的青少年中存在差异。结果:在父母报告ED的情况下,曾经接受过ADHD药物治疗的青少年ED随着时间的推移而下降,而没有ADHD的青少年和从未接受过ADHD药物治疗的青少年ED随着时间的推移没有变化。在自我报告ED的情况下,曾经接受过药物治疗的ADHD青少年比从未接受过药物治疗的ADHD青少年表现出更低的ED,而从未接受过药物治疗的ADHD青少年比没有接受过药物治疗的青少年表现出更大的ED。目前和以前(但不是现在)接受药物治疗的青少年在ED方面没有差异。在父母和自我报告的发现中,当分析集中在基线和随访期间没有改变药物状态的青少年时,观察到的结果模式保持不变。结论:ADHD药物治疗可能对父母报告ED的纵向变化有促进作用,对青少年自我报告ED的同步测量有正常化作用。
{"title":"Emotion dysregulation in adolescents is normalized by ADHD pharmacological treatment.","authors":"Krisztina Kondi, Mária Takács, Evelyn Kovács-Posta, Claudia Szajli, Tünde Sebők-Welker, János M Réthelyi, Nóra Bunford","doi":"10.1186/s40479-024-00268-x","DOIUrl":"10.1186/s40479-024-00268-x","url":null,"abstract":"<p><strong>Background: </strong>Attention-deficit/hyperactivity disorder (ADHD) is associated with emotion dysregulation (ED) and in ADHD, beyond ADHD and comorbidity severity, ED confers increased risk for negative outcomes. First- and second-line ADHD pharmacotherapy is effective at ameliorating core symptoms and improving cognitive functioning and accumulating evidence indicates primairly in children and adults, active ADHD pharmacotherapy has beneficial effects on emotional symptoms. Gaps in knowledge remain about whether in adolescents, ADHD pharmacotherapy has beneficial effects on ED or about the extent to which effects are apparent for discontinued/ past ADHD pharmacotherapy.</p><p><strong>Methods: </strong>Examined, in N = 297 adolescents (M<sub>age</sub>=15.77 years, SD = 1.06; 39.06% girls; n = 86 classified as with ADHD), whether accounting for depression and oppositional symptoms, concurrent and 18-month prospective measures of parent- and self-reported ED (1) differ across adolescents without ADHD, medication-naïve adolescents with ADHD, and ever-medicated (currently or previously) adolescents with ADHD.</p><p><strong>Results: </strong>In case of parent-reported ED, ever medicated adolescents with ADHD exhibited a decline in ED over time whereas adolescents without ADHD and never medicated adolescents with ADHD exhibited no changes in ED over time. In case of self-reported ED, ever-medicated adolescents with ADHD exhibited lower ED than never medicated adolescents with ADHD and never medicated adolescents with ADHD exhibited greater ED than adolescents without ADHD. Currently and previously (but not currently) medicated adolescents did not differ in ED. Across parent- and self-reported findings, observed pattern of results held when analyses focused on adolescents who did not change medication status between baseline and follow-up.</p><p><strong>Conclusions: </strong>ADHD pharmacotherapy may have a boosting effect on longitudinal changes in parent-reported ED and a normalizing effect on concurrent measures of self-reported ED in adolescents.</p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":"12 1","pages":"3"},"PeriodicalIF":4.0,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11789310/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143081722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of social media on triggering nonsuicidal self-injury in adolescents: a comparative ambulatory assessment study. 社交媒体对引发青少年非自杀性自残的影响:一项门诊评估比较研究。
IF 4 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-01-31 DOI: 10.1186/s40479-025-00280-9
Andreas Goreis, Dorothy Chang, Diana Klinger, Heidi-Elisabeth Zesch, Bettina Pfeffer, Sofia-Marie Oehlke, Ulrich W Ebner-Priemer, Laurence Claes, Paul L Plener, Oswald D Kothgassner

Background: Nonsuicidal self-injury (NSSI) is a prevalent and concerning behavior among adolescents, often triggered by negative interpersonal events. As social media is essential in the daily life of adolescents, gaining a better understanding of the impact of negative online events on NSSI urges and behaviors, distinct from that of real-life events, is warranted.

Methods: We recruited 25 adolescents with a history of NSSI and 25 healthy controls. Participants reported on their stress, affect, and NSSI urges four times daily over seven days using ambulatory assessment. We examined the immediate effects of negative events in real-life and on social media on these psychological outcomes.

Results: In adolescents who engage in NSSI, negative events on social media were positively associated with perceived stress, negative affect, and NSSI urges to a greater extent than real-life negative events. However, NSSI events during the sampling period were mostly triggered by real-life events. While the frequency of social media use was generally similar between groups, those with NSSI reported experiencing more negative events on social media.

Conclusions: Our findings highlight the significant impact of social media on the mental health of adolescents who engage in NSSI, possibly exacerbating stress and negative affect more than real-life events. These results underscore the need for targeted interventions addressing online interactions to mitigate NSSI behaviors and improve adolescent mental health.

Trial registration: This study has been registered at the German Clinical Trials Register (ID: DRKS00025905, https://drks.de/search/en/trial/DRKS00025905 ).

背景:非自杀性自伤(non - suicide self injury, NSSI)是青少年中普遍存在的一种令人关注的行为,通常由消极的人际事件引发。由于社交媒体在青少年的日常生活中至关重要,因此有必要更好地了解与现实生活事件不同的负面网络事件对自伤冲动和行为的影响。方法:我们招募了25名有自伤史的青少年和25名健康对照。通过动态评估,参与者报告了他们的压力、情绪和自伤冲动,每天四次,持续七天。我们研究了现实生活和社交媒体上的负面事件对这些心理结果的直接影响。结果:在有自伤行为的青少年中,社交媒体上的负面事件与感知压力、负面情绪和自伤冲动的正相关程度大于现实生活中的负面事件。然而,抽样期间的自伤事件大多是由现实生活事件引发的。虽然两组之间使用社交媒体的频率大致相似,但自伤的人在社交媒体上经历了更多的负面事件。结论:我们的研究结果强调了社交媒体对从事自伤的青少年心理健康的显著影响,可能比现实生活中的事件更严重地加剧了压力和负面影响。这些结果强调了有针对性地干预网络互动以减轻自伤行为和改善青少年心理健康的必要性。试验注册:本研究已在德国临床试验注册中心注册(ID: DRKS00025905, https://drks.de/search/en/trial/DRKS00025905)。
{"title":"Impact of social media on triggering nonsuicidal self-injury in adolescents: a comparative ambulatory assessment study.","authors":"Andreas Goreis, Dorothy Chang, Diana Klinger, Heidi-Elisabeth Zesch, Bettina Pfeffer, Sofia-Marie Oehlke, Ulrich W Ebner-Priemer, Laurence Claes, Paul L Plener, Oswald D Kothgassner","doi":"10.1186/s40479-025-00280-9","DOIUrl":"10.1186/s40479-025-00280-9","url":null,"abstract":"<p><strong>Background: </strong>Nonsuicidal self-injury (NSSI) is a prevalent and concerning behavior among adolescents, often triggered by negative interpersonal events. As social media is essential in the daily life of adolescents, gaining a better understanding of the impact of negative online events on NSSI urges and behaviors, distinct from that of real-life events, is warranted.</p><p><strong>Methods: </strong>We recruited 25 adolescents with a history of NSSI and 25 healthy controls. Participants reported on their stress, affect, and NSSI urges four times daily over seven days using ambulatory assessment. We examined the immediate effects of negative events in real-life and on social media on these psychological outcomes.</p><p><strong>Results: </strong>In adolescents who engage in NSSI, negative events on social media were positively associated with perceived stress, negative affect, and NSSI urges to a greater extent than real-life negative events. However, NSSI events during the sampling period were mostly triggered by real-life events. While the frequency of social media use was generally similar between groups, those with NSSI reported experiencing more negative events on social media.</p><p><strong>Conclusions: </strong>Our findings highlight the significant impact of social media on the mental health of adolescents who engage in NSSI, possibly exacerbating stress and negative affect more than real-life events. These results underscore the need for targeted interventions addressing online interactions to mitigate NSSI behaviors and improve adolescent mental health.</p><p><strong>Trial registration: </strong>This study has been registered at the German Clinical Trials Register (ID: DRKS00025905, https://drks.de/search/en/trial/DRKS00025905 ).</p>","PeriodicalId":48586,"journal":{"name":"Borderline Personality Disorder and Emotion Dysregulation","volume":"12 1","pages":"4"},"PeriodicalIF":4.0,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11786379/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143076004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects on impulsivity and delay discounting of intermittent theta burst stimulation add-on to dialectical behavioral therapy in borderline personality disorder: a randomized, sham-controlled pilot trial. 辩证行为疗法对边缘型人格障碍患者间歇性θ波爆发刺激对冲动性和延迟折扣的影响:一项随机、假对照的试点试验。
IF 4 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-01-14 DOI: 10.1186/s40479-025-00278-3
Milenko Kujovic, Christian Bahr, Mathias Riesbeck, Daniel Benz, Martina Deiß, Zsofia Margittai, Sebastian Henges, Dirk Reinermann, Christian Plewnia, Eva Meisenzahl

Background: Dialectical behavioral therapy (DBT) and repetitive transcranial magnetic stimulation (rTMS) are both effective in treating borderline personality disorder (BPD). Impulsivity and impaired decision-making are prominent features of BPD, and therapeutic interventions targeting these symptoms could lead to significant improvements.

Objective/hypothesis: We hypothesized that intermittent theta burst stimulation (iTBS), a modified rTMS protocol that targets the left dorsolateral prefrontal cortex, would enhance the therapeutic effects of DBT, leading to greater improvements in impulsivity and decision-making compared with sham stimulation.

Methods: We performed a single-blind, randomized, sham-controlled pilot study to evaluate the efficacy of iTBS as an add-on to an 8-week DBT program for BPD in a routine inpatient setting. A total of 53 BPD patients were randomly assigned to receive either iTBS (n = 25) or sham stimulation (n = 28) during weeks 4 to 8 of DBT, and 36 patients met the inclusion criteria for the present analysis (≥ 16 of 20 iTBS/sham sessions and assessment of delay discounting). The study endpoints were the Barratt Impulsiveness Scale-15 for impulsivity and the Monetary Choice Questionnaire for decision-making/delay discounting.

Results: A mixed model repeated measures analysis with a 2 × 2 factorial between-subjects design showed a significant overall improvement over time in impulsivity but not in decision-making/delay discounting. No significant differences were found between iTBS and sham, although post hoc tests revealed significant changes in impulsivity in the iTBS group (meandiff = -4.7, p = .001, Cohen's d = 0.68) but not in the sham group (meandiff = -2.1, p = .077, d = 0.31).

Conclusions: iTBS may offer long-term benefits as an add-on treatment to DBT for impulsivity in BPD, suggesting the need for further investigation in larger-scale studies.

Trial registration: Registered at drks.de (no. DRKS00020413) on January 13, 2020.

背景:辩证行为疗法(DBT)和重复经颅磁刺激(rTMS)均是治疗边缘型人格障碍(BPD)的有效方法。冲动性和决策障碍是BPD的突出特征,针对这些症状的治疗干预可能会导致显著的改善。目的/假设:我们假设间歇性θ波爆发刺激(iTBS),一种针对左背外侧前额叶皮层的改进的rTMS方案,可以增强DBT的治疗效果,与假刺激相比,导致冲动性和决策能力的更大改善。方法:我们进行了一项单盲、随机、假对照的试点研究,以评估iTBS作为8周DBT治疗BPD的附加方案在常规住院患者中的疗效。在DBT的第4至8周,共有53名BPD患者被随机分配接受iTBS (n = 25)或假刺激(n = 28),其中36名患者符合本分析的纳入标准(20次iTBS/假刺激和延迟折扣评估中≥16次)。研究终点为Barratt冲动性量表-15和决策/延迟贴现货币选择问卷。结果:采用2 × 2因子的混合模型重复测量分析显示,随着时间的推移,冲动性总体上有显著改善,但决策/延迟折扣方面没有改善。虽然事后测试显示iTBS组的冲动性有显著变化(meandiff = -4.7, p =),但iTBS组和假手术组之间没有发现显著差异。0.001, Cohen’s d = 0.68),而假手术组无此差异(meandiff = -2.1, p = 0.68)。077, d = 0.31)。结论:iTBS可能作为DBT治疗BPD冲动性的附加治疗提供长期的益处,这表明需要在更大规模的研究中进行进一步的研究。试验报名:在drks.de注册(编号:DRKS00020413)于2020年1月13日发布。
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引用次数: 0
The relationship between borderline personality features and self-efficacy: the mediating role of school adjustment and the moderating role of social support. 边缘型人格特征与自我效能感的关系:学校适应的中介作用和社会支持的调节作用。
IF 4 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-01-07 DOI: 10.1186/s40479-024-00276-x
Tengfei Yu, Xiaodi Niu, Liran Fu, Liju Qian

Background: Adolescents with low self-efficacy may exhibit borderline personality features. This study aimed to investigate the role of school adjustment and social support in the association between self-efficacy and borderline personality features among adolescents.

Methods: Questionnaires were distributed to 2369 adolescents to collect data including general demographic characteristics, borderline personality features, social support, school adjustment, and self-efficacy.

Results: (1) Adolescents' school adjustment and self-efficacy were negatively associated with borderline personality features. (2) The relationship between borderline personality features and self-efficacy was partially mediated by school adjustment. (3) The relationships among borderline personality features, school adjustment, and self-efficacy were moderated by social support. High levels of social support were associated with a stronger negative correlation between borderline personality features and self-efficacy.

Conclusions: School adjustment is a crucial link between borderline personality features and self-efficacy. Although social support can mitigate this relationship to some extent, adolescents with borderline personality features may still face challenges in developing a strong sense of self-efficacy, even in supportive environments.

背景:低自我效能感的青少年可能表现为边缘型人格特征。本研究旨在探讨学校适应和社会支持在青少年自我效能感与边缘型人格特征之间的关系中的作用。方法:对2369名青少年进行问卷调查,收集一般人口学特征、边缘型人格特征、社会支持、学校适应、自我效能感等数据。结果:(1)青少年的学校适应和自我效能感与边缘型人格特征呈负相关。(2)学校适应在边缘型人格特征与自我效能感之间起部分中介作用。(3)社会支持对边缘性人格特征、学校适应和自我效能感之间的关系有调节作用。高水平的社会支持与边缘人格特征和自我效能之间的负相关关系更强。结论:学校适应是边缘型人格特征与自我效能之间的重要纽带。虽然社会支持可以在一定程度上缓解这种关系,但具有边缘性人格特征的青少年在发展强烈的自我效能感方面可能仍然面临挑战,即使在支持的环境中也是如此。
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引用次数: 0
The place of subjective emptiness in the structure of personality. 主观空性在人格结构中的地位。
IF 4 2区 医学 Q1 PSYCHIATRY Pub Date : 2024-12-04 DOI: 10.1186/s40479-024-00274-z
Christopher J Hopwood, Julija Gjorgjieva

Background: Subjective emptiness is a transdiagnostic clinical dimension related to suicide, distress, and other maladaptive outcomes. Although it is typically conceptualized as a symptom of borderline personality disorder, it has a different pattern of correlates than other symptoms of that phenotype and is present in individuals with other diagnoses. The goals of this study were to replicate and extend previous findings regarding the place of emptiness as a standalone construct within a relatively comprehensive array of personality features.

Method: A sample of 992 anonymous participants (M = 45.37 years, SD = 16.53) who were census-matched to the US population completed an online survey including measures of emptiness, normal-range and maladaptive trait domains and aspects, as well as interpersonal values and problems.

Results: Overall, the pattern of correlations suggests that people who report feelings of emptiness tend to have negative emotions, be socially withdrawn, and are low in energy.

Conclusion: These findings highlight the relevance of subjective emptiness beyond the borderline category, replicate previous findings regarding the personality and psychopathology correlates of subjective emptiness, and portray a particular profile of personality that represents a risk factor for the experience of subjective emptiness.

背景:主观空虚是一种跨诊断的临床维度,与自杀、痛苦和其他适应不良的结果有关。虽然它通常被概念化为边缘型人格障碍的一种症状,但它与该表型的其他症状有不同的相关模式,并且存在于其他诊断的个体中。这项研究的目的是复制和扩展先前的研究结果,将空虚作为一个相对全面的人格特征中的独立结构。方法:选取与美国人口相匹配的992名匿名参与者(M = 45.37岁,SD = 16.53)完成一项在线调查,包括空虚感、正常范围和不适应特征领域和方面,以及人际价值观和问题。结果:总体而言,相关模式表明,报告空虚感的人往往有负面情绪,社交孤僻,精力不足。结论:这些发现强调了主观空虚的相关性,超越了边缘类别,重复了先前关于主观空虚的人格和精神病理学相关的发现,并描绘了一种特定的人格特征,它代表了主观空虚体验的风险因素。
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引用次数: 0
Associations between maternal personality dysfunction and emotion suppression and adolescent emotion suppression. 母亲人格功能障碍与情绪抑制和青少年情绪抑制之间的关系。
IF 4 2区 医学 Q1 PSYCHIATRY Pub Date : 2024-11-27 DOI: 10.1186/s40479-024-00273-0
Jennifer J Phillips, Cynthia L Smith, Martha Ann Bell

Background: Adaptive strategies of emotion regulation are important for adolescents, as maladaptive strategies of such can manifest as psychopathology that is sometimes severe. Individual biological characteristics and influences from peers have been shown to have an effect on the development of emotion regulation strategies in adolescents. Maternal factors, however, have received less attention in this age group regarding how they might predict emotion regulation in adolescents. Given that prior work has demonstrated that certain maternal factors, like emotion regulation and personality, play a crucial role in the development of emotion regulation strategies in early childhood, we sought to examine these associations in adolescents in our current study.

Methods: Adolescents and their mothers (n = 123) both self-reported data on their own emotion regulation, and mothers also self-reported data on their own personality dysfunction. We operationalized maternal and adolescent emotion regulation as emotion suppression, a maladaptive emotion regulation strategy that is commonly used by adolescents.

Results: Our data demonstrated that both maternal emotion suppression and interpersonal personality dysfunction were positively associated with adolescent emotion suppression. No associations among maternal intrapersonal personality functioning and adolescent emotion suppression were detected.

Conclusions: Maternal personality dysfunction and emotion suppression both independently predicted adolescent emotion suppression use. These results support the idea that maternal characteristics play a role in shaping emotion regulation in adolescence.

背景:适应性情绪调节策略对青少年非常重要,因为不适应性情绪调节策略会表现为心理病态,有时甚至是严重的心理病态。个体的生理特征和来自同伴的影响已被证明会对青少年情绪调节策略的发展产生影响。然而,在这一年龄组中,母亲因素如何预测青少年的情绪调节却较少受到关注。鉴于之前的研究已经证明,某些母亲因素(如情绪调节和个性)在幼儿期情绪调节策略的发展中起着至关重要的作用,我们试图在本研究中考察这些因素与青少年的关系:方法:青少年及其母亲(n = 123)均自我报告了自己的情绪调节数据,母亲也自我报告了自己的人格功能障碍数据。我们将母亲和青少年的情绪调节操作化为情绪抑制,这是青少年常用的一种适应不良的情绪调节策略:结果:我们的数据显示,母亲的情绪抑制和人际关系人格功能障碍与青少年的情绪抑制呈正相关。结论:母性人格功能障碍与青少年情绪抑制之间没有关联:结论:母亲人格功能障碍和情绪抑制都能独立预测青少年情绪抑制的使用。结论:母性人格功能障碍和情绪压抑都能独立预测青少年情绪压抑的使用,这些结果支持了母性特征在青少年情绪调节中发挥作用的观点。
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引用次数: 0
You say it's not me: the influence of offering external explanations of rejection and acceptance behavior on the perception of benevolence in borderline personality disorder. 你说不是我:为边缘型人格障碍患者的拒绝和接受行为提供外部解释对其仁慈感的影响。
IF 4 2区 医学 Q1 PSYCHIATRY Pub Date : 2024-11-25 DOI: 10.1186/s40479-024-00275-y
Anna Schulze, Berit Rommelfanger, Elisabeth Schendel, Kornelius Immanuel Kammler-Sücker, Stefanie Lis

Background: Interpersonal impairments in patients diagnosed with borderline personality disorder (BPD) are characterized by the fear of being rejected and high levels of loneliness. Potential underlying factors are alterations in the processing of social interactions and the associated perceptions of social partners. In this regard, BPD patients tend to attribute the cause of negative rather than positive events to their own person and to perceive others as less trustworthy than healthy controls (HCs). To date, no study has investigated whether the effect of experimentally influenced causal attributions of social interactions on the perception of a social partner differs between BPD patients and HCs.

Methods: A new virtual reality paradigm was developed to investigate the perception of benevolence following the induction of social rejection and acceptance, while experimentally manipulating whether an external cause for this behavior was provided. The data of 62 participants (32 HCs, 30 BPD patients) were analyzed using linear mixed-effects models. Associations of benevolence ratings with attributional style, rejection sensitivity, self-esteem, childhood trauma, and loneliness were investigated via correlational and multiple linear regression analyses.

Results: Across both groups, a social partner was rated as less benevolent following rejection than following acceptance. An external explanation mitigated this negative effect of rejection. Overall, benevolence ratings were lower in BPD patients than in HCs. This group difference was stronger following acceptance than following rejection. Independent of acceptance and rejection, an external explanation was associated with a higher level of benevolence only in the HC group. No associations of the effects of the experimental conditions with attributional style, childhood trauma, rejection sensitivity, self-esteem, or loneliness were found.

Conclusion: Our findings indicate that acceptance and provided external explanations for rejection have a less positive impact on the perception of a social partner's attitude toward oneself in BPD patients than in HCs. More research is needed to identify predictors of benevolence perception and which steps of social information processing are altered. The therapeutic implications include the importance of strengthening the perception and enjoyment of being accepted as well as improving the mentalizing ability of BPD patients.

背景:被诊断为边缘型人格障碍(BPD)的患者的人际交往障碍表现为害怕被拒绝和高度孤独。潜在的潜在因素是社会交往处理过程中的改变以及对社会伙伴的相关看法。在这方面,BPD 患者倾向于将消极事件而非积极事件的原因归咎于自己,并认为他人比健康对照组(HCs)更不可信。迄今为止,还没有研究调查过受实验影响的社会交往因果归因对 BPD 患者和 HCs 对社会伙伴的感知是否有不同的影响:方法:研究人员开发了一种新的虚拟现实范式,以调查在诱导社交拒绝和接受后对仁慈的感知,同时通过实验操纵是否为这种行为提供了外部原因。我们使用线性混合效应模型分析了62名参与者(32名HC,30名BPD患者)的数据。通过相关分析和多元线性回归分析,研究了仁慈评分与归因风格、拒绝敏感性、自尊、童年创伤和孤独感之间的关系:结果:在两组人中,被拒绝后对社会伙伴的仁慈评价低于被接受后对社会伙伴的仁慈评价。外部解释减轻了拒绝的负面影响。总体而言,BPD 患者的仁慈评分低于 HC 患者。这种群体差异在接受后比拒绝后更明显。与接受和拒绝无关的是,外部解释只与高危人群的仁慈程度较高有关。实验条件的影响与归因风格、童年创伤、拒绝敏感性、自尊或孤独感均无关联:我们的研究结果表明,与普通人相比,BPD 患者对拒绝的接受和外部解释对其感知社会伙伴对自己态度的积极影响较小。还需要进行更多的研究,以确定仁慈感知的预测因素以及社会信息处理的哪些步骤发生了改变。其治疗意义包括,必须加强 BPD 患者对被接纳的感知和享受,并提高他们的心智化能力。
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引用次数: 0
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Borderline Personality Disorder and Emotion Dysregulation
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