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Addressing Colorectal Cancer Disparities in Unhoused Populations: A Call for Equitable Access and Compassionate Care 应对无住房人群中的结直肠癌差异:呼吁公平就医和体恤关怀
IF 1.4 4区 医学 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-05-02 DOI: 10.1055/s-0044-1786531
Housing is essential for health. Unhoused individuals have markedly worse health status than the general population culminating in higher rates of premature mortality. Cancer is a leading cause of death in older unhoused adults. Caring for unhoused patients at risk for or with colorectal cancer poses challenges at every stage of oncologic care: prevention, screening, diagnosis, treatment, and follow-up. These challenges result in later stages at diagnosis and worse overall survival. Health systems can work to advance health equity in colorectal cancer in unhoused patients by improving access to care, transitions of care, health care quality, and focusing on socioeconomic/environmental impact.
住房对健康至关重要。没有住房的人的健康状况明显不如普通人,过早死亡的比例也更高。癌症是无房老年人的主要死因。照顾有结肠直肠癌风险或患有结肠直肠癌的无房病人在肿瘤治疗的每个阶段都会面临挑战:预防、筛查、诊断、治疗和随访。这些挑战导致患者在诊断时处于较晚阶段,总体生存率较低。医疗系统可以通过改善医疗服务的可及性、医疗服务的过渡、医疗服务的质量,以及关注社会经济/环境影响,来促进无住房患者的结直肠癌健康公平。
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引用次数: 0
Anastomosis after Bowel Resection for Crohn's Disease: State of the Art Review 克罗恩病肠道切除术后的吻合术:最新技术回顾
IF 1.4 4区 医学 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-05-02 DOI: 10.1055/s-0044-1786534
Recurrence after surgically induced remission in Crohn's disease remains a topic of research and debate with significant clinical implications for overall quality of life and intestinal and defecatory functions. While the surgeon continues to play a critical role in surgical prophylaxis of recurrence, optimal results will only be obtained in the setting of a true multidisciplinary team approach, following the principles of “the right surgery, on the right patient, at the right time, performed by the right surgeon, supported by the right team.” The centerpiece of surgical prophylaxis is the intestinal anastomosis. The ideal anastomosis after resection for Crohn's disease should be safe and reliable, as postoperative septic complications have been shown to increase the risk of recurrence; result in a wide lumen and a configuration that would not impede enteric flow; exclude or excise the mesentery, a known culprit in primary and recurrent disease; and preserve vascularization and innervation. This article will review the evidence supporting the above-mentioned surgical principles and the long-term results of the different anastomotic configurations.
手术诱导克罗恩病缓解后的复发仍然是一个研究和辩论的主题,对整体生活质量、肠道和排便功能具有重要的临床影响。虽然外科医生在手术预防复发方面仍扮演着重要角色,但只有在真正的多学科团队合作下,遵循 "在正确的时间、由正确的外科医生、在正确的团队支持下,为正确的患者实施正确的手术 "的原则,才能获得最佳效果。手术预防的核心是肠吻合术。克罗恩病切除术后的理想吻合口应该是安全可靠的,因为术后化脓性并发症已被证明会增加复发的风险;形成宽阔的管腔和不妨碍肠道流动的结构;排除或切除肠系膜--已知的原发性和复发性疾病的罪魁祸首;并保留血管和神经支配。本文将回顾支持上述手术原则的证据,以及不同吻合口结构的长期效果。
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引用次数: 0
Difficulties and Disparities in Colorectal Cancer End-of-Life Care: A Patient's Story 结直肠癌临终关怀的困难与差距:一位患者的故事
IF 1.4 4区 医学 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-04-29 DOI: 10.1055/s-0044-1786393
Stacy Ranson, Danielle Noreika, Emily B. Rivet

Patients with advanced colorectal cancer nearing the end of life require a multidisciplinary approach to address the unique challenges they face. Using a case vignette, we outline the various stages of a patient's journey with advanced rectal cancer and the common obstacles to their care as they interface with the medical system. We highlight how Black persons might be vulnerable to differences in screening, treatment, procedural interventions, end-of-life care, and health care decision-making. The article also addresses how health inequities and barriers relating to concordant treatment goals can impact the relationship between patient and surgeon. This vignette illustrates the importance of ensuring a team approach to treatment and the value of early involvement of palliative medicine for patients with advanced colorectal cancer.

临近生命终点的晚期结直肠癌患者需要采用多学科方法来应对他们所面临的独特挑战。通过一个案例,我们概述了晚期直肠癌患者所经历的各个阶段,以及他们在与医疗系统接触时所面临的常见障碍。我们强调了黑人如何容易受到筛查、治疗、程序干预、临终关怀和医疗决策等方面差异的影响。文章还讨论了健康不平等和与一致治疗目标相关的障碍如何影响患者和外科医生之间的关系。这则小故事说明了确保团队治疗方法的重要性,以及姑息医学对晚期结直肠癌患者早期参与的价值。
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引用次数: 0
Minimally Invasive Management of Complicated and Re-operative Crohn's Disease 微创治疗并发症和再手术克罗恩病
IF 1.4 4区 医学 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-04-29 DOI: 10.1055/s-0044-1786515
Conor Kinford, Vitaliy Poylin

Minimally invasive techniques for the surgical management of Crohn's disease have become the recommended approach for initial surgical intervention in noncomplicated patients as there is lower morbidity for patients without compromising treatment outcomes. There has been a push to expand minimally invasive approaches to complex and recurrent diseases, trying to benefit these difficult patients. However, until recently there have been little data to support the adoption of minimally invasive surgery (MIS) in these scenarios. This article aims to build on the 2019 Clinics in Colon and Rectal Surgery article on complex Crohn's and MIS by introducing new data in support of these approaches. Decisions for technique should be based on patient characteristics, but minimally invasive techniques have emerged as valid and possibly superior for complex and recurrent disease.

微创技术用于克罗恩病的外科治疗已成为非复杂性患者初始外科干预的推荐方法,因为患者的发病率较低,且不会影响治疗效果。人们一直在推动将微创方法扩展到复杂和复发性疾病,试图让这些疑难杂症患者受益。然而,直到最近,支持在这些情况下采用微创手术(MIS)的数据还很少。本文旨在以 2019 年《结肠和直肠外科临床》杂志关于复杂克罗恩病和 MIS 的文章为基础,介绍支持这些方法的新数据。技术决策应基于患者特征,但微创技术已成为治疗复杂和复发性疾病的有效方法,而且可能更具优势。
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引用次数: 0
Socially Responsible Surgical Care. 对社会负责的外科护理。
IF 1.2 4区 医学 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-04-26 eCollection Date: 2025-01-01 DOI: 10.1055/s-0044-1786530
Pasithorn A Suwanabol
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引用次数: 0
Nonfistulizing Perianal Crohn's Disease 非瘘性肛周克罗恩病
IF 1.4 4区 医学 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2024-04-19 DOI: 10.1055/s-0044-1786198
Emily Simon, Emily Steinhagen

Perianal Crohn's disease (CD) includes a wide range of nonfistulizing sequela, including fissures and ulcers, skin tags, anal stricture, and anal cancer. Symptoms related to perianal manifestations of CD are often disabling and have a significant impact on patients' quality of life. They include pain, drainage, bleeding, difficulty with hygiene and may cause secondary difficulties with sexual and defecatory dysfunction. The care of patients with perianal CD requires a thoughtful approach, including detailed history taking, physical examination, and often multidisciplinary care teams to maximize quality of life and ameliorate symptoms.

肛周克罗恩病(CD)包括多种非瘘性后遗症,包括肛裂和溃疡、皮肤赘生物、肛门狭窄和肛门癌。与 CD 肛周表现相关的症状通常会导致残疾,并对患者的生活质量产生重大影响。这些症状包括疼痛、引流、出血、卫生困难,并可能继发性功能障碍和排便障碍。对肛周 CD 患者的护理需要周到的方法,包括详细的病史采集、体格检查和多学科护理团队,以最大限度地提高生活质量和改善症状。
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引用次数: 0
Management of Severe Colitis and Toxic Megacolon 严重结肠炎和中毒性巨结肠的处理方法
IF 1.4 4区 医学 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2023-12-29 DOI: 10.1055/s-0043-1777665
Marjorie R. Liggett, Hasan B. Alam

Severe colitis is a well-defined condition encompassing several etiologies but is most often caused by severe ulcerative colitis or Clostridioides difficile infection. Severe colitis can evolve into toxic colitis, or toxic megacolon when associated with bowel dilation and systemic manifestations, resulting in a life-threatening scenario where multidisciplinary management is often required. Medical management continues to play an important role in the initial treatment of toxic megacolon. However, timely surgical intervention can be lifesaving.

重症结肠炎是一种定义明确的病症,包含多种病因,但最常见的病因是重症溃疡性结肠炎或艰难梭菌感染。如果伴有肠扩张和全身症状,严重结肠炎可演变为中毒性结肠炎或中毒性巨结肠,从而危及生命,通常需要多学科治疗。内科治疗在中毒性巨结肠的初期治疗中仍然发挥着重要作用。然而,及时的手术干预可以挽救生命。
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引用次数: 0
Large Bowel Obstruction: Etiologies, Diagnosis, and Management 大肠梗阻:病因、诊断和处理
IF 1.4 4区 医学 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2023-12-29 DOI: 10.1055/s-0043-1777452
Kevin A. Chen, Muneera R. Kapadia

Large bowel obstructions (LBOs) often require urgent surgical intervention. Diagnosis relies on astute history and physical examination, as well as imaging with computed tomography (CT) scan for stable patients. Because of the high mortality associated with colonic perforation in patients with LBOs, decisive surgical decision-making is needed for optimal outcomes. This review seeks to provide an overview of the etiologies of LBO, diagnosis, and general management principles, as well as specific management for the most common etiologies, including colorectal cancer and strictures.

大肠梗阻(LBO)通常需要紧急手术治疗。诊断依赖于敏锐的病史和体格检查,对于病情稳定的患者,还需要进行计算机断层扫描(CT)成像。由于 LBO 患者结肠穿孔的死亡率很高,因此需要果断做出手术决策,以获得最佳治疗效果。本综述旨在概述 LBO 的病因、诊断和一般处理原则,以及最常见病因(包括结肠直肠癌和狭窄)的具体处理方法。
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引用次数: 0
Management of Acute Hemorrhoidal Crisis: Evaluation, Treatment, and Special Considerations 急性痔疮危象的处理:评估、治疗和特殊考虑因素
IF 1.4 4区 医学 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2023-12-28 DOI: 10.1055/s-0043-1777663
Ayman Khan, Arielle E. Kanters

Hemorrhoidal disease is one of most common pathologies seen by colorectal and general surgeons. Although hemorrhoids themselves are a normal anatomic occurrence, development of symptomatic disease, usually due to bleeding, prolapse, or thrombosis, can cause significant patient distress. Acute presentation related to significant thrombosis or bleeding is referred to as acute hemorrhoidal crisis. Management of this pathology varies from nonoperative intervention for symptom control to definitive incisional or excisional hemorrhoidectomy. Here we will explore the approach to evaluating and treating acute hemorrhoidal crises.

痔疮是结直肠外科医生和普通外科医生最常见的病症之一。虽然痔疮本身是一种正常的解剖现象,但通常由于出血、脱垂或血栓形成而引起的症状性疾病会给患者带来极大的痛苦。与严重血栓形成或出血有关的急性症状被称为急性痔疮危象。对这种病症的处理方法多种多样,从控制症状的非手术干预到明确的切开或切除痔切除术。在此,我们将探讨评估和治疗急性痔疮危象的方法。
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引用次数: 0
Colonic Volvulus 结肠溃疡
IF 1.4 4区 医学 Q4 GASTROENTEROLOGY & HEPATOLOGY Pub Date : 2023-12-28 DOI: 10.1055/s-0043-1777664
Samantha L. Savitch, Calista M. Harbaugh

Colonic volvulus represents 10 to 15% of all large bowel obstructions in the United States. It most commonly occurs in the sigmoid colon or cecum. Morbidity and mortality from colonic volvulus are high. It is therefore essential to have a high level of suspicion based on presentation and expedient diagnosis and management to prevent progression to ischemia or perforation. Broad goals of management include evaluation of colon viability, relief of obstruction, and prevention of recurrence. Endoscopic and surgical approaches vary based on the site of volvulus, presence of ischemia or perforation, and patient characteristics. This review outlines the epidemiology, presentation, diagnosis, and management of colonic volvulus. A contemporary diagnostic and treatment algorithm is included.

在美国,结肠空肠占所有大肠梗阻的 10%至 15%。它最常发生在乙状结肠或盲肠。结肠空洞症的发病率和死亡率都很高。因此,必须根据患者的表现高度怀疑,并迅速进行诊断和处理,以防止恶化为缺血或穿孔。治疗的总体目标包括评估结肠存活能力、缓解梗阻和预防复发。内镜和手术方法因肠管外翻的部位、缺血或穿孔的存在以及患者的特征而异。本综述概述了结肠肠卷的流行病学、表现、诊断和治疗。其中包括当代诊断和治疗算法。
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Clinics in Colon and Rectal Surgery
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