Pub Date : 2023-06-30DOI: 10.1007/s11908-023-00808-6
N. Squillace, V. Cogliandro, Alice Ranzani, Nicholas Brian Bana, P. Bonfanti
{"title":"Human Papilloma Virus Related Cancers in People Living with HIV","authors":"N. Squillace, V. Cogliandro, Alice Ranzani, Nicholas Brian Bana, P. Bonfanti","doi":"10.1007/s11908-023-00808-6","DOIUrl":"https://doi.org/10.1007/s11908-023-00808-6","url":null,"abstract":"","PeriodicalId":48839,"journal":{"name":"Current Infectious Disease Reports","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46867859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-08DOI: 10.1007/s11908-023-00805-9
Marta González-Sanz, Pedro Berzosa, Francesca F Norman
Purpose of review: The objective of this review was to provide an update on recent malaria epidemiology, both globally and in non-endemic areas, to identify the current distribution and repercussions of genetically diverse Plasmodium species and summarize recently implemented intervention and prevention tools.
Recent findings: Notable changes in malaria epidemiology have occurred in recent years, with an increase in the number of total cases and deaths globally during 2020-2021, in part attributed to the COVID-19 pandemic. The emergence of artemisinin-resistant species in new areas and the expanding distribution of parasites harbouring deletions of the pfhrp2/3 genes have been concerning. New strategies to curb the burden of this infection, such as vaccination, have been implemented in certain endemic areas and their performance is currently being evaluated.
Summary: Inadequate control of malaria in endemic regions may have an effect on imported malaria and measures to prevent re-establishment of transmission in malaria-free areas are essential. Enhanced surveillance and investigation of Plasmodium spp. genetic variations will contribute to the successful diagnosis and treatment of malaria in future. Novel strategies for an integrated One Health approach to malaria control should also be strengthened.
{"title":"Updates on Malaria Epidemiology and Prevention Strategies.","authors":"Marta González-Sanz, Pedro Berzosa, Francesca F Norman","doi":"10.1007/s11908-023-00805-9","DOIUrl":"10.1007/s11908-023-00805-9","url":null,"abstract":"<p><strong>Purpose of review: </strong>The objective of this review was to provide an update on recent malaria epidemiology, both globally and in non-endemic areas, to identify the current distribution and repercussions of genetically diverse Plasmodium species and summarize recently implemented intervention and prevention tools.</p><p><strong>Recent findings: </strong>Notable changes in malaria epidemiology have occurred in recent years, with an increase in the number of total cases and deaths globally during 2020-2021, in part attributed to the COVID-19 pandemic. The emergence of artemisinin-resistant species in new areas and the expanding distribution of parasites harbouring deletions of the pfhrp2/3 genes have been concerning. New strategies to curb the burden of this infection, such as vaccination, have been implemented in certain endemic areas and their performance is currently being evaluated.</p><p><strong>Summary: </strong>Inadequate control of malaria in endemic regions may have an effect on imported malaria and measures to prevent re-establishment of transmission in malaria-free areas are essential. Enhanced surveillance and investigation of Plasmodium spp. genetic variations will contribute to the successful diagnosis and treatment of malaria in future. Novel strategies for an integrated One Health approach to malaria control should also be strengthened.</p>","PeriodicalId":48839,"journal":{"name":"Current Infectious Disease Reports","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10248987/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9715480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-01DOI: 10.1007/s11908-023-00804-w
Sarah L McGuinness, Stephen Muhi, P. Britton, K. Leder
{"title":"Japanese Encephalitis: Emergence in Australia","authors":"Sarah L McGuinness, Stephen Muhi, P. Britton, K. Leder","doi":"10.1007/s11908-023-00804-w","DOIUrl":"https://doi.org/10.1007/s11908-023-00804-w","url":null,"abstract":"","PeriodicalId":48839,"journal":{"name":"Current Infectious Disease Reports","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45711448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Purpose of review: Poor hand hygiene is well documented as a factor in healthcare-associated infections and excellent rates of hand hygiene remains elusive.
Recent findings: There is increased use of universal or increased gloving to minimize hand contamination, but its use does not replace hand hygiene opportunities. There is significant interest in electronic hand hygiene monitoring systems, but they are not without their unique issues. Behavioral psychology remains a significant factor in motivating hand hygiene behaviors; even in COVID-19, hand hygiene rates initially improved but trended down back to baseline while still dealing with the pandemic.
Summary: More emphasis should be placed on the how to properly perform hand hygiene and why it is so important, as well as the role of gloves, is needed. Continued investment and awareness of their status as role models from both system leadership and senior healthcare providers are needed.
{"title":"Healthcare Personnel Hand Hygiene Compliance: Are We There Yet?","authors":"JoDee Armstrong-Novak, Hui Yu Juan, Kaila Cooper, Pamela Bailey","doi":"10.1007/s11908-023-00806-8","DOIUrl":"10.1007/s11908-023-00806-8","url":null,"abstract":"<p><strong>Purpose of review: </strong>Poor hand hygiene is well documented as a factor in healthcare-associated infections and excellent rates of hand hygiene remains elusive.</p><p><strong>Recent findings: </strong>There is increased use of universal or increased gloving to minimize hand contamination, but its use does not replace hand hygiene opportunities. There is significant interest in electronic hand hygiene monitoring systems, but they are not without their unique issues. Behavioral psychology remains a significant factor in motivating hand hygiene behaviors; even in COVID-19, hand hygiene rates initially improved but trended down back to baseline while still dealing with the pandemic.</p><p><strong>Summary: </strong>More emphasis should be placed on the how to properly perform hand hygiene and why it is so important, as well as the role of gloves, is needed. Continued investment and awareness of their status as role models from both system leadership and senior healthcare providers are needed.</p>","PeriodicalId":48839,"journal":{"name":"Current Infectious Disease Reports","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10213575/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10092969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1007/s11908-023-00802-y
Tumader Khouja, Erinne N Kennedy, K. Suda
{"title":"Antibiotic Prophylaxis for Tooth Extractions and Dental Implants, A Narrative Review","authors":"Tumader Khouja, Erinne N Kennedy, K. Suda","doi":"10.1007/s11908-023-00802-y","DOIUrl":"https://doi.org/10.1007/s11908-023-00802-y","url":null,"abstract":"","PeriodicalId":48839,"journal":{"name":"Current Infectious Disease Reports","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"53208960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-01Epub Date: 2023-03-07DOI: 10.1007/s11908-023-00798-5
Johanna B Holm, Kayla A Carter, Jacques Ravel, Rebecca M Brotman
Purpose of review: Vaginal lactobacilli are recognized as important drivers of genital health including protection against bacterial vaginosis and sexually transmitted infections. Lactobacillus iners is distinct from L. crispatus, L. gasseri, and L. jensenii by its high global prevalence in vaginal microbiomes, relatively small genome, production of only L-lactic acid, and inconsistent associations with genital health outcomes. In this review, we summarize our current understanding of the role of L. iners in the vaginal microbiome, highlight the importance of strain-level consideration for this species, and explain that while marker gene-based characterization of the composition of the vaginal microbiota does not capture strain-level resolution, whole metagenome sequencing can aid in expanding our understanding of this species in genital health.
Recent findings: L. iners exists in the vaginal microbiome as a unique combination of strains. The functional repertoires of these strain combinations are likely wide and contribute to the survival of this species in a variety of vaginal microenvironments. In published studies to date, strain-specific effects are aggregated and may yield imprecise estimates of risk associated with this species.
Summary: The worldwide high prevalence of Lactobacillus iners warrants more research into its functional roles in the vaginal microbiome and how it may directly impact susceptibility to infections. By incorporating strain-level resolution into future research endeavors, we may begin to appreciate L. iners more thoroughly and identify novel therapeutic targets for a variety of genital health challenges.
综述的目的:阴道乳杆菌被认为是生殖器健康的重要驱动力,包括防止细菌性阴道病和性传播感染。阴道乳杆菌(Lactobacillus iners)与L. crispatus、L. gasseri和L. jensenii不同,它在全球阴道微生物组中的流行率很高,基因组相对较小,只产生L-乳酸,而且与生殖器健康结果的关系不一致。在这篇综述中,我们总结了目前我们对 L. iners 在阴道微生物群中作用的理解,强调了考虑菌株水平对该物种的重要性,并解释说,虽然基于标记基因的阴道微生物群组成特征描述不能捕捉到菌株水平的分辨率,但全基因组测序有助于扩大我们对该物种在生殖器健康中作用的理解:最新研究结果:阴道微生物群中的 L. iners 是一种独特的菌株组合。这些菌株组合的功能范围可能很广,有助于该物种在各种阴道微环境中生存。小结:阴道乳杆菌在全球范围内的高流行率需要对其在阴道微生物组中的功能作用以及如何直接影响感染易感性进行更多的研究。通过将菌株级分辨率纳入未来的研究工作,我们可能会开始更透彻地了解内氏乳杆菌,并确定新的治疗目标,以应对各种生殖健康挑战。
{"title":"<i>Lactobacillus iners</i> and genital health: molecular clues to an enigmatic vaginal species.","authors":"Johanna B Holm, Kayla A Carter, Jacques Ravel, Rebecca M Brotman","doi":"10.1007/s11908-023-00798-5","DOIUrl":"10.1007/s11908-023-00798-5","url":null,"abstract":"<p><strong>Purpose of review: </strong>Vaginal lactobacilli are recognized as important drivers of genital health including protection against bacterial vaginosis and sexually transmitted infections. <i>Lactobacillus iners</i> is distinct from <i>L. crispatus, L. gasseri</i>, and <i>L. jensenii</i> by its high global prevalence in vaginal microbiomes, relatively small genome, production of only L-lactic acid, and inconsistent associations with genital health outcomes. In this review, we summarize our current understanding of the role of <i>L. iners</i> in the vaginal microbiome, highlight the importance of strain-level consideration for this species, and explain that while marker gene-based characterization of the composition of the vaginal microbiota does not capture strain-level resolution, whole metagenome sequencing can aid in expanding our understanding of this species in genital health.</p><p><strong>Recent findings: </strong><i>L. iners</i> exists in the vaginal microbiome as a unique combination of strains. The functional repertoires of these strain combinations are likely wide and contribute to the survival of this species in a variety of vaginal microenvironments. In published studies to date, strain-specific effects are aggregated and may yield imprecise estimates of risk associated with this species.</p><p><strong>Summary: </strong>The worldwide high prevalence of <i>Lactobacillus iners</i> warrants more research into its functional roles in the vaginal microbiome and how it may directly impact susceptibility to infections. By incorporating strain-level resolution into future research endeavors, we may begin to appreciate <i>L. iners</i> more thoroughly and identify novel therapeutic targets for a variety of genital health challenges.</p>","PeriodicalId":48839,"journal":{"name":"Current Infectious Disease Reports","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10209668/pdf/nihms-1896832.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9555866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-14DOI: 10.1007/s11908-023-00800-0
Caleb C. McLeod, K. Tan, Razieh Kebriaei, J. Abdul‐Mutakabbir
{"title":"Clinical Appraisal of Cefiderocol in the Treatment of Non-fermenting Gram-Negative Bacilli","authors":"Caleb C. McLeod, K. Tan, Razieh Kebriaei, J. Abdul‐Mutakabbir","doi":"10.1007/s11908-023-00800-0","DOIUrl":"https://doi.org/10.1007/s11908-023-00800-0","url":null,"abstract":"","PeriodicalId":48839,"journal":{"name":"Current Infectious Disease Reports","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46827530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-03-09DOI: 10.1007/s11908-023-00801-z
Mariel Becker, Ryan H. Sobel
{"title":"Vulvovaginal Candidiasis in Postmenopausal Women","authors":"Mariel Becker, Ryan H. Sobel","doi":"10.1007/s11908-023-00801-z","DOIUrl":"https://doi.org/10.1007/s11908-023-00801-z","url":null,"abstract":"","PeriodicalId":48839,"journal":{"name":"Current Infectious Disease Reports","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46862001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-22DOI: 10.1007/s11908-023-00797-6
J. Sobel
{"title":"Role of Antifungal Susceptibility Tests in the Treatment of Vulvovaginal Candidiasis","authors":"J. Sobel","doi":"10.1007/s11908-023-00797-6","DOIUrl":"https://doi.org/10.1007/s11908-023-00797-6","url":null,"abstract":"","PeriodicalId":48839,"journal":{"name":"Current Infectious Disease Reports","volume":null,"pages":null},"PeriodicalIF":3.1,"publicationDate":"2023-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41689050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}