Revista Internacional De Andrologia最新文献

Objective

To make an extensive evaluation about the effects of histopathological findings acquired from the resection materials of patients who underwent transurethral resection of prostate (TUR-P) due to benign prostate hyperplasia (BPH) on postoperative urethral stricture formation.

Materials and methods

Among patients who had TUR-P due to BPH and were followed up for minimum 6 months, 51 patients detected to have urethral stricture based on endoscopic imaging were included in the urethral stricture group (Group 1) and 52 patients without urethral stricture were included in the control group (Group 2). The relation between histopathological findings of TURP materials and postoperative stricture occurrence was investigated.

Results

No difference in age, prostate volume, operation time and postoperative catheterization time was detected among the groups (p = 0.86, p = 0.13, p = 0.06, p = 0.32, respectively). Average time until the urethral stricture diagnosis in the group with urethral stricture was measured as 57.9 ± 27.2 days. In our study, inflammation intensity in peri-urethral, stromal and periglandular areas and intraglandular destruction ratios were higher in urethral stricture group (Group 1) (p = 0.048, p = 0.3, p = 0.03, p = 0.01, respectively). Again, it was detected that neutrophil, plasmocyte and eosinophil cell ratios were higher in peri-urethral, stromal and periglandular areas and lymphocyte values were lower compared to the control group.

Conclusion

Acquired data has shown that acute inflammatory attacks may be related to urethral stricture with a mostly chronic inflammation background in the prostate. During histopathological examination of prostate tissue acquired through TURP, especially high peri-urethral neutrophil, plasmocyte and eosinophil cell ratios and intra-glandular destruction ratios are important for predicting postoperative urethral stricture occurrences.

Introduction

New HIV diagnoses and sexually transmitted infections (STIs) continue to be a public health problem in Spain. Since the beginning of HIV infection in our country, prevention campaigns have been developed by the Health Services regarding sexual and reproductive health. Several authors warn about the poor evaluation of these campaigns.

Objective

To evaluate the design and evaluation strategies of the sexual health campaigns developed in Spain from 1987 to 2016.

Methods

Observational epidemiological study based on a detailed retrospective collection of data obtained from the National AIDS Plan, official agencies and Health Services about the design and evaluation of developed sexual health campaigns. Statistical analysis was performed using UNAIDS indicators system.

Results

82 campaigns have been developed since 1987, 27 have been aimed at young people. In 100% of campaigns aimed at young people, general information about HIV infection and the promotion of condom use has been addressed; however, other issues about risky sexual behavior have virtually not been included. The prevention of pregnancy in young people is present in less than 25% of campaigns. The quantity of planning and evaluation reports of the available campaigns is very low.

Conclusion

The data indicate the need to improve actions aimed at sexually active young people, with more planned and evaluated actions for regarding UNAIDS criteria and efficacy indicators.

Radical orchiectomy in testicular cancer patients can have a negative impact on body image and self-esteem. Reconstructive surgery with testicular prosthesis might mitigate this burden. We conducted a questionnaire-based study aiming to evaluate our patients’ satisfaction with testicular prosthesis. Overall satisfaction was rated as excellent or good in 97.7%. The main complaints were related to the prosthesis’ inappropriate texture (45.5%), size (18.1%) or position (15.9%). Among men interviewed, 59% considered that having a normal looking scrotum was either extremely important or important for their self-esteem. The majority (88.2%) stated they would make the same decision again, and nearly all patients would recommend it to other men with testicular cancer. We believe testicular implants should always be offered, leaving the final decision to the patient.

The extrusion of a penile prosthesis is an indicator of infection and implies its removal, causing fibrosis and shortening of the penis.

We present a 62-year-old man, to whom we implanted a hydraulic prosthesis, and three weeks later we underwent salvage surgery by extrusion of the activation pump. After removing the prosthesis, we wash the cavities with four dilutions. The 1st to 50% of hydrogen peroxide; the 2nd to 50% of povidone iodine; the 3rd with 1 g of cefazolin and 40 mg of tobramycin, the 4th with 80 mg of gentamicin and 500 mg of vancomycin. In the act we implanted a malleable prosthesis bathed in antibiotic solutions.

The postoperative period was satisfactory. A year later, the patient presents an adequate penile length and aesthetic appearance, maintaining satisfactory sexual relations.

Surgical rescue by washing with antiseptic solutions and a malleable prosthesis implant, minimizes the risk of reinfection, preserving sexual function.

Primary testicular lymphoma is a very rare entity. However, its clinical course is poor with a high recurrence and low survival rate. Given its low prevalence, we present 2 cases with an update on the treatment and progression of this disease.

Introduction and Objectives

Prostate cancer (PCa) is the most widespread malignancy within men. Androgen deprivation therapy (ADT), which is the central component of advanced PCa treatment, causes side effects. The goal of this study was to examine the metabolic changes and bioelectrical impedance analysis differences in PCa patients who received ADT.

Materials and methods

After age-related match-pair analysis, a total of 519 patients with PCa and control group who had benign disease were enrolled in the study. Biochemical blood parameters and TANITA measurements were recorded for all patients. Patients were categorized into three groups, ADT group (Group 1, n = 124) and non-ADT group (Group 2, n = 248), control group (Group 3, n = 147).

Results

The mean age of groups was similar. Body mass index, waist circumference, body fat mass and fat ratio, which were among the TANITA parameters, were higher in group 1 (p < 0.05). Total cholesterol, high density lipoprotein, non- high density lipoprotein, triglycerids and fasting blood glucose values were also higher in group 1 (p < 0.05). Myocardial infarction and metabolic syndrome rates were also higher in this group.

Conclusions

While the use of ADT is manifested by an increase in fat mass and fat ratio in body composition, it negatively affects waist circumference measurements. It is associated with metabolically unfit body composition changes that predispose to diabetes mellitus and may increase cardio-vascular disease. For this reason, it is necessary to be careful about metabolic and endocrinological diseases in long-term therapy.

Introduction

In 2019, 9,828 new cases of HIV and 5,825 of AIDS were detected in Mexico, the migrant population is considered highly vulnerable, which is presumed to be due to unfavorable conditions in their transit through the country, an important variable in the context of sexual health is the perception that they may have about being or not at risk. A study of perception of contracting HIV can have important implications for health.

Objective

To determine the association between the perception of risk for HIV and safe sex in migrants from the northern border of Mexico.

Methods

The design was predictive correlational and cross-sectional, sample of 302 migrants from two border cities of Tamaulipas, systematic random probability sampling.

Results

It was found that about 90% were men with a mean age of (M = 33,25, SD = 9,62) years, in general, migrants have a low perception of risk for HIV and this was correlated with safe sex (r_s = -,134, p =,020), furthermore, a regression analysis showed that the perception of risk for HIV has a predictive effect on safe sex (β = -, 143, F = 6,27 _{[gl = 1,300]}, p = 0,013),

Conclusion

Migrants are a group that requires interest in the field of research related to sexuality, despite being a vulnerable group and identified as at risk, their perception of acquiring HIV is low, this variable should be considered of importance in future research in the sexual field of migrants, because it can be used in conjunction with others as a model or as a mediator.

Objective

To investigate the transrectal and scrotal ultrasonographic features of acquired obstructive azoospermia and evaluate the role of ultrasonography in the location diagnosis of acquired obstructive azoospermia patients.

Methods

Retrospectively analysis of 92 cases of acquired obstructive azoospermia in recent years. All the patients underwent transrectal and scrotal ultrasonography. The ultrasonographic features were observed of testis, epididymis, scrotal segment of vas deferens, seminal vesicle, ejaculatory duct and prostate. Eighty cases with normal semen were taken as control group.

Results

Among the 92 cases of acquired obstructive azoospermia, 28 cases were prostate midline cyst, 32 cases were stone or calcification of the ejaculation duct and 21 cases were chronic seminal vesicle inflammation, which were found through transrectal ultrasonography; 27 cases were vas deferens dilation, 30 cases had abnormal mass of epididymis tail, 31 cases were epididymis thickness with reticular change, 8 cases were cystic dilatation of rete testis, which were found through scrotal ultrasonography. Compared with the control group, ultrasound examination increased the detection rate of distal seminal duct lesions and epididymal lesions in acquired obstructive azoospermia patients (p < .01). Comparison of testicular volume between case group and control group did not reveal significant difference (p > .05). The thickness of the head, body and tail of epididymis in case group was significantly bigger than that in control group (p < .01).

Conclusion

Transrectal and scrotal ultrasonography can find lesions in different parts of the seminal passage. Acquired obstructive azoospermia patients have increased rate of distal seminal duct lesions, epididymal lesions and epididymis volume. Transrectal and scrotum ultrasonography can provide reliable imaging evidence for the location diagnosis of acquired obstructive azoospermia.

Cavernous body thrombosis is a rare condition. The etiology and pathophysiology of this entity is still poorly understood and there is no clear diagnostic and treatment algorithm. The objective of this article is to publish a clinical case of a partial segmental thrombosis of the corpus cavernosum and present a flow chart for diagnosis and treatment based on the review of the published literature on this disease.

Background

We previously postulated that orgasmic sensation may occur through recently discovered genital taste bud-like structures. The interaction between the pudendal nerve and Onuf's nucleus may be important for developing orgasmic information. The study aims to investigate whether ischemic damage to Onuf's nucleus-pudendal network following spinal subarachnoid hemorrhage (SAH) causes taste bud degeneration or not.

Methods

The study was conducted on 22 fertile male rabbits who were divided into three groups: control (GI; n = 5), SHAM (GII; n = 5) and study (GIII; n = 12). Isotonic solution, .7 cm³, for the SHAM, and .7 cm³ homologous blood was injected into spinal subarachnoid spaces at S2 level of the study group. Two weeks later, Onuf's nucleus, pudendal ganglia and the taste bud-like structures of the penile urethra were examined histopathologically. Degenerated neuron densities of Onuf's nucleus, pudendal ganglia and atrophic taste bud-like structures were estimated per mm³ and the results analyzed statistically.

Results

The mean degenerated neuron densities of taste bud-like structures, Onuf's nucleus and pudendal ganglia were estimated as 2 ± 1/mm³, 5 ± 1/mm³, 6 ± 2/mm³ in GI; 12 ± 4/mm³, 35 ± 9/mm³, 188 ± 31/mm³, in GII and 41 ± 8/mm³, 215 ± 37/mm³, 1321 ± 78/mm³, in GIII. Spinal SAH induced neurodegeneration in Onuf's nucleus, pudendal ganglia and taste bud atrophy was significantly different between GI/GII (p < .005); GII/GIII (p < .0005) and GI/GIII (p < .0001).

Conclusion

Ischemic neuronal degenerations of Onuf's nucleus and pudendal ganglia following spinal SAH lead to genital taste bud-like structure atrophy. This mechanism may be responsible for sexual anhedonia and sterility in cases with spinal cord injury, which has not been documented so far. More studies are needed.