Purpose: Digital workflows provide significant advances in prosthodontics, especially in terms of accuracy, reduced treatment duration, and quality of life. Moreover, additive manufacturing (AM) is particularly adapted for the fabrication of personalized complex prototypes required for the prosthetic rehabilitation of maxillofacial defects. However, the integration of AM in maxillofacial prosthetics (MP) protocols is challenging. The purpose of this scoping review was to evaluate the clinical contribution of AM to the management of patients requiring MP.
Methods: This scoping review followed the PRISMA recommendations. Searches were conducted until December 2024 using the PubMed, Scopus, and Web of Science databases. Selection was performed by reviewing titles and abstracts, followed by full-text evaluation according to the established inclusion and exclusion criteria. In vitro studies and case reports were excluded.
Results: Of the 1526 retrieved articles, 16 were included. These clinical studies were 14 case series and 2 cohort studies, with a sample size averaging ∼8 participants per study. The applications were 3D-printed prostheses, prosthetic prototypes, master casts or molds, and implant guides. These articles demonstrated that AM enhanced clinical management of MP in terms of cost, production time, aesthetics, retention, accuracy, quality of life, and comfort. The replication of skin texture remained the only criterion requiring improvement.
Conclusions: Workflows integrating computer-aided design and AM offer alternatives to conventional procedures for the management of MP. However, the organization of digital workflows suggests an initial investment related to installation costs and the recruitment of trained technicians. Larger-scale studies with extended follow-up periods are needed to establish whether a digital workflow incorporating AM represents a standard treatment approach.
目的:数字化工作流程为修复学提供了显著的进步,特别是在准确性、缩短治疗时间和生活质量方面。此外,增材制造(AM)特别适用于颌面缺陷修复所需的个性化复杂原型的制造。然而,AM在颌面修复(MP)协议中的集成是具有挑战性的。本综述的目的是评估AM对需要MP的患者管理的临床贡献。方法:本综述遵循PRISMA的建议。使用PubMed、Scopus和Web of Science数据库进行搜索直到2024年12月。通过审查标题和摘要进行选择,然后根据既定的纳入和排除标准对全文进行评估。排除体外研究和病例报告。结果:1526篇检索文献中,16篇被纳入。这些临床研究包括14个病例系列和2个队列研究,每项研究的样本量平均为8名参与者。这些应用包括3d打印假肢、假肢原型、主铸件或模具以及植入物指南。这些文章表明,AM在成本、制作时间、美观、保留、准确性、生活质量和舒适度方面增强了MP的临床管理。皮肤纹理的复制仍然是唯一需要改进的标准。结论:集成计算机辅助设计和AM的工作流程为MP的管理提供了传统程序的替代方案。然而,数字化工作流程的组织建议与安装费用和招聘训练有素的技术人员相关的初始投资。需要进行更大规模的研究,延长随访期,以确定包含AM的数字工作流程是否代表标准治疗方法。
{"title":"Clinical application of additive manufacturing in maxillofacial prosthetics: A scoping review.","authors":"Hélène Magro, Adrien Laran, Adrien Naveau","doi":"10.1111/jopr.70050","DOIUrl":"https://doi.org/10.1111/jopr.70050","url":null,"abstract":"<p><strong>Purpose: </strong>Digital workflows provide significant advances in prosthodontics, especially in terms of accuracy, reduced treatment duration, and quality of life. Moreover, additive manufacturing (AM) is particularly adapted for the fabrication of personalized complex prototypes required for the prosthetic rehabilitation of maxillofacial defects. However, the integration of AM in maxillofacial prosthetics (MP) protocols is challenging. The purpose of this scoping review was to evaluate the clinical contribution of AM to the management of patients requiring MP.</p><p><strong>Methods: </strong>This scoping review followed the PRISMA recommendations. Searches were conducted until December 2024 using the PubMed, Scopus, and Web of Science databases. Selection was performed by reviewing titles and abstracts, followed by full-text evaluation according to the established inclusion and exclusion criteria. In vitro studies and case reports were excluded.</p><p><strong>Results: </strong>Of the 1526 retrieved articles, 16 were included. These clinical studies were 14 case series and 2 cohort studies, with a sample size averaging ∼8 participants per study. The applications were 3D-printed prostheses, prosthetic prototypes, master casts or molds, and implant guides. These articles demonstrated that AM enhanced clinical management of MP in terms of cost, production time, aesthetics, retention, accuracy, quality of life, and comfort. The replication of skin texture remained the only criterion requiring improvement.</p><p><strong>Conclusions: </strong>Workflows integrating computer-aided design and AM offer alternatives to conventional procedures for the management of MP. However, the organization of digital workflows suggests an initial investment related to installation costs and the recruitment of trained technicians. Larger-scale studies with extended follow-up periods are needed to establish whether a digital workflow incorporating AM represents a standard treatment approach.</p>","PeriodicalId":49152,"journal":{"name":"Journal of Prosthodontics-Implant Esthetic and Reconstructive Dentistry","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145530966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Geany Ferreira Rodrigues, Isaac Augusto Dantas Nogueira, Nicole Escórcio de Meneses, Ana Letícia Daniel Fontenele, Francisbênia Alves Silvestre, Ana Carolina Lima Moreira, Lívia Maria Sales Pinto Fiamengui, Karina Matthes de Freitas Pontes, Raniel Fernandes Peixoto
Purpose: This systematic review evaluated the effects of simulated gastric acid (SGA) on surface and mechanical properties of dental ceramics to answer the research question: Does immersion in SGA alter the surface roughness, microhardness, fracture strength, and color of dental ceramics?
Methods: A literature search was conducted in PubMed, Scopus, Web of Science, Embase, Open Gray, and Google Scholar, in February 2025. Independent reviewers selected and analyzed in vitro studies assessing one or more outcomes-roughness, microhardness, fracture strength, or color-after acid exposure. Data were extracted independently, and risk of bias was assessed using the RoBDEMAT tool.
Results: Out of 2,111 studies, 22 were included. Ceramics analyzed were lithium disilicate (n = 15), polymer-infiltrated feldspathic (n = 11), zirconia (n = 11), feldspathic (n = 8), zirconia-reinforced lithium silicate (n = 7), and leucite-reinforced (n = 4). Surface roughness changes were material-dependent, with feldspathic ceramics most affected and zirconia most stable. Microhardness generally decreased across ceramics. Fracture strength remained mostly unchanged, except for occasional reductions. Polymer-infiltrated ceramics and zirconia showed the greatest color stability. Specimen shapes and dimensions varied across studies, reflecting differences in study aims and testing protocols. Most studies showed appropriate outcome reporting, statistical analysis, and test standardization (>90%). However, operator blinding, when applicable, was not reported in any of the included studies. Randomization (> 87%) and sample size calculation (50%) were also frequently missing.
Conclusion: Surface, mechanical, and optical properties of ceramics were affected by acid exposure, varying by material. Zirconia and polymer-infiltrated ceramics show greater stability. Methodological heterogeneity limits conclusions, underscoring the need for standardized protocols and clinical validation.
{"title":"Effects of gastric acid on surface roughness, microhardness, fracture strength, and color change of dental ceramics: A systematic review of in vitro studies.","authors":"Geany Ferreira Rodrigues, Isaac Augusto Dantas Nogueira, Nicole Escórcio de Meneses, Ana Letícia Daniel Fontenele, Francisbênia Alves Silvestre, Ana Carolina Lima Moreira, Lívia Maria Sales Pinto Fiamengui, Karina Matthes de Freitas Pontes, Raniel Fernandes Peixoto","doi":"10.1111/jopr.70057","DOIUrl":"https://doi.org/10.1111/jopr.70057","url":null,"abstract":"<p><strong>Purpose: </strong>This systematic review evaluated the effects of simulated gastric acid (SGA) on surface and mechanical properties of dental ceramics to answer the research question: Does immersion in SGA alter the surface roughness, microhardness, fracture strength, and color of dental ceramics?</p><p><strong>Methods: </strong>A literature search was conducted in PubMed, Scopus, Web of Science, Embase, Open Gray, and Google Scholar, in February 2025. Independent reviewers selected and analyzed in vitro studies assessing one or more outcomes-roughness, microhardness, fracture strength, or color-after acid exposure. Data were extracted independently, and risk of bias was assessed using the RoBDEMAT tool.</p><p><strong>Results: </strong>Out of 2,111 studies, 22 were included. Ceramics analyzed were lithium disilicate (n = 15), polymer-infiltrated feldspathic (n = 11), zirconia (n = 11), feldspathic (n = 8), zirconia-reinforced lithium silicate (n = 7), and leucite-reinforced (n = 4). Surface roughness changes were material-dependent, with feldspathic ceramics most affected and zirconia most stable. Microhardness generally decreased across ceramics. Fracture strength remained mostly unchanged, except for occasional reductions. Polymer-infiltrated ceramics and zirconia showed the greatest color stability. Specimen shapes and dimensions varied across studies, reflecting differences in study aims and testing protocols. Most studies showed appropriate outcome reporting, statistical analysis, and test standardization (>90%). However, operator blinding, when applicable, was not reported in any of the included studies. Randomization (> 87%) and sample size calculation (50%) were also frequently missing.</p><p><strong>Conclusion: </strong>Surface, mechanical, and optical properties of ceramics were affected by acid exposure, varying by material. Zirconia and polymer-infiltrated ceramics show greater stability. Methodological heterogeneity limits conclusions, underscoring the need for standardized protocols and clinical validation.</p>","PeriodicalId":49152,"journal":{"name":"Journal of Prosthodontics-Implant Esthetic and Reconstructive Dentistry","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145531013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohamed Sherif Omar, Chao-Chieh Yang, Dean Morton, Wei-Shao Lin
This technique describes a scanner-agnostic digital workflow for generating dynamic mandibular motion from static virtual interocclusal records using a custom artificial intelligence (AI) algorithm and user interface. Virtual records of mandibular positions, including maximum intercuspation, protrusion, and lateral excursions, were captured with an intraoral scanner and processed through a custom interface developed using Python, an open-source, script-based programming language. The program interpolates intermediate positions using quantified point tracking and exports a motion path file compatible with dental computer-aided design software. By leveraging AI and open-source tools, this method offers a cost-effective, non-vendor-specific solution for integrating individualized jaw motion into digital prosthodontic workflows.
{"title":"Scanner-agnostic dynamic jaw motion generation from virtual static excursive records using open-source Python-based artificial intelligence (AI) interpolation.","authors":"Mohamed Sherif Omar, Chao-Chieh Yang, Dean Morton, Wei-Shao Lin","doi":"10.1111/jopr.70051","DOIUrl":"https://doi.org/10.1111/jopr.70051","url":null,"abstract":"<p><p>This technique describes a scanner-agnostic digital workflow for generating dynamic mandibular motion from static virtual interocclusal records using a custom artificial intelligence (AI) algorithm and user interface. Virtual records of mandibular positions, including maximum intercuspation, protrusion, and lateral excursions, were captured with an intraoral scanner and processed through a custom interface developed using Python, an open-source, script-based programming language. The program interpolates intermediate positions using quantified point tracking and exports a motion path file compatible with dental computer-aided design software. By leveraging AI and open-source tools, this method offers a cost-effective, non-vendor-specific solution for integrating individualized jaw motion into digital prosthodontic workflows.</p>","PeriodicalId":49152,"journal":{"name":"Journal of Prosthodontics-Implant Esthetic and Reconstructive Dentistry","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145514689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Almira Ada Diken Turksayar, Mehmet Esad Güven, Simge Dagistan, Dilem Toksoy, Özay Önöral
Purpose: The purpose of this study was to assess the dimensional trueness and fit of 3-unit monolithic zirconia restorations fabricated using various additive manufacturing (AM) techniques-namely, stereolithography (SLA), digital light processing (DLP), and lithography-based ceramic manufacturing (LCM)-in comparison with the computer numerical control (CNC) method.
Materials and methods: A total of 32 three-unit posterior fixed partial dentures (FPDs) were fabricated using 3 different additive AM methods (SLA, DLP, and LCM) and CNC as the control group. In all groups, 3 mol% yttria-stabilized tetragonal zirconia polycrystalline (Y-TZP) was used. The restorations, the restorations placed on the model, and the model itself were digitized. For the purpose of trueness and internal fit analysis, all STL datasets were imported into a high-precision metrology-grade 3-dimensional inspection software (Geomagic Control X 2022; 3D Systems) and virtually divided into four regions: intaglio, occlusal, axial, and marginal. Surface deviations were analyzed by using the root mean square (RMS) method, while the triple scan method was used for internal fit. Obtained data were then computed by using two-way ANOVA, followed by Bonferroni and Tukey post hoc tests (α = 0.05).
Results: SLA, CNC, and LCM provided similar and clinically acceptable marginal and internal trueness (p > 0.05). Conversely, the DLP method exhibited a significantly higher discrepancy in all regions, particularly in the marginal and intaglio surfaces (p ≤ 0.001). The lowest overall RMS deviation was observed in the SLA group (39.88 ± 4.84 µm), while the highest internal gap was found in the DLP group (218.29 ± 11.88 µm).
Conclusion: Additive manufacturing methods affected the fabrication trueness and fit of the 3-unit zirconia FPDs. Since the restorations produced by the DLP method had higher RMS and internal gap values, adjustment is required prior to clinical use.
目的:本研究的目的是评估使用各种增材制造(AM)技术(即立体光刻(SLA),数字光处理(DLP)和基于光刻的陶瓷制造(LCM))制造的3单元整体氧化锆修复体的尺寸真实性和拟合性,并与计算机数控(CNC)方法进行比较。材料与方法:采用三种不同的增材增材制造方法(SLA、DLP、LCM)和CNC作为对照组,制作32颗三单元后牙固定局部义齿(fpd)。所有组均使用3mol %钇稳定的四方氧化锆多晶(Y-TZP)。修复,模型上的修复和模型本身都被数字化了。为了准确性和内部拟合分析,将所有STL数据集导入高精度计量级三维检测软件(Geomagic Control X 2022; 3D Systems)中,并将其虚拟分为凹版、咬合、轴向和边缘四个区域。采用均方根(RMS)法分析表面偏差,采用三重扫描法进行内拟合。采用双因素方差分析计算所得数据,并进行Bonferroni和Tukey事后检验(α = 0.05)。结果:SLA、CNC和LCM提供相似且临床可接受的边缘和内部真实度(p < 0.05)。相反,DLP方法在所有区域,特别是在边缘和凹版表面上显示出明显更高的差异(p≤0.001)。SLA组整体RMS偏差最小(39.88±4.84µm), DLP组内部间隙最大(218.29±11.88µm)。结论:增材制造方法影响了3单元氧化锆fpd的制作准确性和贴合度。由于DLP法修复体的RMS和内部间隙值较高,因此在临床使用前需要进行调整。
{"title":"Comparative analysis of dimensional trueness and adaptation of 3-unit monolithic zirconia restorations fabricated with subtractive and additive technologies.","authors":"Almira Ada Diken Turksayar, Mehmet Esad Güven, Simge Dagistan, Dilem Toksoy, Özay Önöral","doi":"10.1111/jopr.70059","DOIUrl":"https://doi.org/10.1111/jopr.70059","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to assess the dimensional trueness and fit of 3-unit monolithic zirconia restorations fabricated using various additive manufacturing (AM) techniques-namely, stereolithography (SLA), digital light processing (DLP), and lithography-based ceramic manufacturing (LCM)-in comparison with the computer numerical control (CNC) method.</p><p><strong>Materials and methods: </strong>A total of 32 three-unit posterior fixed partial dentures (FPDs) were fabricated using 3 different additive AM methods (SLA, DLP, and LCM) and CNC as the control group. In all groups, 3 mol% yttria-stabilized tetragonal zirconia polycrystalline (Y-TZP) was used. The restorations, the restorations placed on the model, and the model itself were digitized. For the purpose of trueness and internal fit analysis, all STL datasets were imported into a high-precision metrology-grade 3-dimensional inspection software (Geomagic Control X 2022; 3D Systems) and virtually divided into four regions: intaglio, occlusal, axial, and marginal. Surface deviations were analyzed by using the root mean square (RMS) method, while the triple scan method was used for internal fit. Obtained data were then computed by using two-way ANOVA, followed by Bonferroni and Tukey post hoc tests (α = 0.05).</p><p><strong>Results: </strong>SLA, CNC, and LCM provided similar and clinically acceptable marginal and internal trueness (p > 0.05). Conversely, the DLP method exhibited a significantly higher discrepancy in all regions, particularly in the marginal and intaglio surfaces (p ≤ 0.001). The lowest overall RMS deviation was observed in the SLA group (39.88 ± 4.84 µm), while the highest internal gap was found in the DLP group (218.29 ± 11.88 µm).</p><p><strong>Conclusion: </strong>Additive manufacturing methods affected the fabrication trueness and fit of the 3-unit zirconia FPDs. Since the restorations produced by the DLP method had higher RMS and internal gap values, adjustment is required prior to clinical use.</p>","PeriodicalId":49152,"journal":{"name":"Journal of Prosthodontics-Implant Esthetic and Reconstructive Dentistry","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2025-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145514680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}