{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":49215,"journal":{"name":"Critical Care and Resuscitation","volume":"28 1","pages":"Article 100167"},"PeriodicalIF":1.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146211224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":49215,"journal":{"name":"Critical Care and Resuscitation","volume":"28 1","pages":"Article 100158"},"PeriodicalIF":1.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146211226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":49215,"journal":{"name":"Critical Care and Resuscitation","volume":"28 1","pages":"Article 100169"},"PeriodicalIF":1.7,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146211225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Discrepancies between laboratory sodium and point-of-care arterial blood gas sodium values may lead to delayed interpretation of, and intervention on, the results. We studied the mean difference between these two techniques and assessed the degree of agreement.
Design
A multicentre, retrospective, observational study was conducted.
Setting
Twelve intensive care units in Queensland, Australia, with tertiary-level hospitals accounting for 81% of admissions were included in the study.
Participants
Adult patients with at least one paired laboratory sodium and arterial blood gas measurement during their intensive care unit admission were a part of this study.
Main outcome measures
Main outcome measures included mean difference between laboratory sodium and point-of-care sodium measurement, with a positive difference demonstrating laboratory sodium values higher than arterial blood gas sodium values.
Results
A total of 65,042 patients with 224,383 paired samples were included in the analysis. The Bland–Altman mean difference of laboratory sodium and arterial blood gas sodium was 0.72 mmol/L (95% limit of agreement [LoA]: 4.35) with a Deming regression slope of 0.93 (95% confidence interval: 0.92, 0.94) and intercept +10.07 (p < 0.001). On subgroup analysis of hyponatraemia, eunatraemia and hypernatraemia a mean difference (95% LoA) of 1.53 mmol/L (4.21), 0.15 mmol/L (4.39), and −1.02 mmol/L (5.37), was calculated, respectively. Patients with severe hyperglycaemia and normal albumin had a mean difference (95% LoA) of −1.85 mmol/L (4.78). Analysis of mild, moderate, and severe subgroups within both hyponatraemic and hypernatraemic samples showed increasing mean differences, with severe hyponatraemia showing a mean difference of 2.01 mmol/L (95% LoA: 8.08) and severe hypernatraemia showing a mean difference of −4.7 mmol/L (95% LoA: 15.46).
Conclusions
Point-of-care arterial blood gas sodium measurements show small mean differences in eunatraemia and good agreement with paired laboratory samples in adult intensive care unit patients. Caution should be applied when interchanging results between laboratory and point-of-care sodium values in patients with moderate to severe dysnatraemia, as serial measurements using different methods during treatment are unlikely to be within a clinically acceptable range. This is important when caring for patient groups with severe hyponatraemia and induced hypernatraemia, and serial measurement may be better achieved with point-of-care testing due to a combination of ease of access, repeatability, and lower cost.
{"title":"A comparison of sodium concentration measured in laboratory autoanalyser versus point-of-care blood gas machine: A retrospective, multicentre, analytical study in a large adult intensive care unit population","authors":"Keegan Hunter BMedSc MD , Chris Anstey MBBS BSc MSc FANZCA FCICM PhD , Alexander Nesbitt BSc MBBS FCICM AFHEA , Karthik Venkatesh BMed MD FCICM , Dinesh Parmar MD FRCA FCICM , Amanda Corley RN PhD , Marissa Daniels MBBS , Jatinder Grewal FCICM, FANZCA, GchPOM , Kevin B. Laupland MD, PhD , Mahesh Ramanan BSc(Med) MBBS(Hons) MMed(Clin Epi) FCICM , Alexis Tabah MD FCICM , James McCullough MMed FCICM , Aashish Kumar MBBS FCICM , Antony G. Attokaran MBBS FCICM FRACP , Stephen Luke MBBS BSc(Hons) FCICM , Peter Garrett MBBS, BSc(Hons) FCICM FACEM FCEM , Stephen Whebell MBBS FCICM , Sebastiaan Blank FCICM , Philippa McIlroy BPhty (Hons) MBBS FCICM , Kyle C. White BSc MBBS MPH FCICM FRACP","doi":"10.1016/j.ccrj.2025.100149","DOIUrl":"10.1016/j.ccrj.2025.100149","url":null,"abstract":"<div><h3>Objective</h3><div>Discrepancies between laboratory sodium and point-of-care arterial blood gas sodium values may lead to delayed interpretation of, and intervention on, the results. We studied the mean difference between these two techniques and assessed the degree of agreement.</div></div><div><h3>Design</h3><div>A multicentre, retrospective, observational study was conducted.</div></div><div><h3>Setting</h3><div>Twelve intensive care units in Queensland, Australia, with tertiary-level hospitals accounting for 81% of admissions were included in the study.</div></div><div><h3>Participants</h3><div>Adult patients with at least one paired laboratory sodium and arterial blood gas measurement during their intensive care unit admission were a part of this study.</div></div><div><h3>Main outcome measures</h3><div>Main outcome measures included mean difference between laboratory sodium and point-of-care sodium measurement, with a positive difference demonstrating laboratory sodium values higher than arterial blood gas sodium values.</div></div><div><h3>Results</h3><div>A total of 65,042 patients with 224,383 paired samples were included in the analysis. The Bland–Altman mean difference of laboratory sodium and arterial blood gas sodium was 0.72 mmol/L (95% limit of agreement [LoA]: 4.35) with a Deming regression slope of 0.93 (95% confidence interval: 0.92, 0.94) and intercept +10.07 (p < 0.001). On subgroup analysis of hyponatraemia, eunatraemia and hypernatraemia a mean difference (95% LoA) of 1.53 mmol/L (4.21), 0.15 mmol/L (4.39), and −1.02 mmol/L (5.37), was calculated, respectively. Patients with severe hyperglycaemia and normal albumin had a mean difference (95% LoA) of −1.85 mmol/L (4.78). Analysis of mild, moderate, and severe subgroups within both hyponatraemic and hypernatraemic samples showed increasing mean differences, with severe hyponatraemia showing a mean difference of 2.01 mmol/L (95% LoA: 8.08) and severe hypernatraemia showing a mean difference of −4.7 mmol/L (95% LoA: 15.46).</div></div><div><h3>Conclusions</h3><div>Point-of-care arterial blood gas sodium measurements show small mean differences in eunatraemia and good agreement with paired laboratory samples in adult intensive care unit patients. Caution should be applied when interchanging results between laboratory and point-of-care sodium values in patients with moderate to severe dysnatraemia, as serial measurements using different methods during treatment are unlikely to be within a clinically acceptable range. This is important when caring for patient groups with severe hyponatraemia and induced hypernatraemia, and serial measurement may be better achieved with point-of-care testing due to a combination of ease of access, repeatability, and lower cost.</div></div>","PeriodicalId":49215,"journal":{"name":"Critical Care and Resuscitation","volume":"27 4","pages":"Article 100149"},"PeriodicalIF":1.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145684685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The optimal approach to haemodynamic resuscitation in patients with septic shock is uncertain and will be evaluated in The Australasian Resuscitation In Sepsis Evaluation: FLUid or vasopressors In emergency Department Sepsis (ARISE FLUIDS) trial.
Objective
The objective of this study was to describe the prespecified ARISE FLUIDS statistical analysis plan (SAP).
Design, setting, participants, and interventions
The ARISE FLUIDS trial is a 1000-participant international multicentre randomised controlled trial comparing restricted intravenous fluid volume and earlier introduction of vasopressors (vasopressor strategy) to larger initial intravenous fluid volume and later introduction of vasopressors if required (fluids strategy) in adults with early septic shock presenting to the emergency department in participating sites in Australia, New Zealand and Ireland.
Main outcome measures
The primary outcome is days alive and out of hospital at 90 days post randomisation, and the difference in medians between the two treatment groups will be estimated using a linear quantile mixed-effect regression model. Secondary outcomes include duration of survival censored at day 90, ventilator-, vasopressor-, and acute renal replacement–free days censored at day 28 and death or disability at 6 and 12 months
Conclusion
ARISE FLUIDS will compare the effects of a vasopressor vs. fluids strategy on days alive and out of hospital at 90 days in adults with early septic shock. The prespecified SAP is reported here to mitigate analysis bias.
{"title":"Statistical analysis plan for the Australasian Resuscitation in sepsis evaluation: FLUid or vasopressors in emergency department sepsis (ARISE FLUIDS) trial","authors":"Elissa M. Milford BSc, MBBS, PhD, FCICM , Stephen P.J. Macdonald BSc (Hons), MBChB, PhD, DCH, FRCP (Edin), FACEM , Ary Serpa-Neto MD, MSc, PhD, FCICM , Anthony Delaney FCICM, FACEM, PhD , Alisa M. Higgins PhD, MPH, BPhysio (Hons) , Belinda Howe RN, BAppSc (Nursing), CCCert, MPH , Sandra L. Peake FCICM, PhD , ARISE FLUIDS Investigators","doi":"10.1016/j.ccrj.2025.100157","DOIUrl":"10.1016/j.ccrj.2025.100157","url":null,"abstract":"<div><h3>Background</h3><div>The optimal approach to haemodynamic resuscitation in patients with septic shock is uncertain and will be evaluated in The Australasian Resuscitation In Sepsis Evaluation: FLUid or vasopressors In emergency Department Sepsis (ARISE FLUIDS) trial.</div></div><div><h3>Objective</h3><div>The objective of this study was to describe the prespecified ARISE FLUIDS statistical analysis plan (SAP).</div></div><div><h3>Design, setting, participants, and interventions</h3><div>The ARISE FLUIDS trial is a 1000-participant international multicentre randomised controlled trial comparing restricted intravenous fluid volume and earlier introduction of vasopressors (vasopressor strategy) to larger initial intravenous fluid volume and later introduction of vasopressors if required (fluids strategy) in adults with early septic shock presenting to the emergency department in participating sites in Australia, New Zealand and Ireland.</div></div><div><h3>Main outcome measures</h3><div>The primary outcome is days alive and out of hospital at 90 days post randomisation, and the difference in medians between the two treatment groups will be estimated using a linear quantile mixed-effect regression model. Secondary outcomes include duration of survival censored at day 90, ventilator-, vasopressor-, and acute renal replacement–free days censored at day 28 and death or disability at 6 and 12 months</div></div><div><h3>Conclusion</h3><div>ARISE FLUIDS will compare the effects of a vasopressor vs. fluids strategy on days alive and out of hospital at 90 days in adults with early septic shock. The prespecified SAP is reported here to mitigate analysis bias.</div></div>","PeriodicalId":49215,"journal":{"name":"Critical Care and Resuscitation","volume":"27 4","pages":"Article 100157"},"PeriodicalIF":1.7,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145736601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-22DOI: 10.1016/j.ccrj.2025.100126
David Mogg MBBS, BSc, MMed , James Walsham MBChB, FCICM
Objective
The objective of this study was to assess the Subarachnoid Haemorrhage International Trialist (SAHIT) prediction model in a tertiary adult intensive care unit (ICU) cohort when assessing patient outcomes against predicted outcomes, firstly by assessing the discrimination and validation of the model in the Princess Alexandra Hospital (PA) intensive care cohort and secondly comparing the predicted outcomes using the SAHIT model to the actual cohort outcomes using a Monte Carlo simulation.
Methods
Six logistic regression models designed by the SAHIT Collaboration Group were applied to the PA cohort considering early predictive factors such as clinical grade and treatment modality to predict the risk of both mortality and unfavourable outcome at 6 months according to the Glasgow Outcome Score. The six SAHIT logistic regression models were applied to a retrospectively collected cohort of aneurysmal subarachnoid patients who were admitted to the ICU, generating individual risk scores for mortality and poor functional outcome. Area under the curve (AUC) and calibration slope/intercept and Brier score were used to assess the strength of the model in interpreting the current data set. A Monte Carlo analysis was used to compare the actual mortality outcomes to the predicted outcomes to determine if the cohort performance was better or worse than predicted by the mortality model.
Results
Overall, the PA cohort actual mortality was higher than the predicted mortality rate based on the risk scores generated by the SAHIT models, demonstrated by Monte Carlo simulation using the SAHIT model risk scores. The core, neuroimaging, and full models for functional outcome produced AUCs of 0.719 (95% confidence interval [CI]: 0.55–0.84), 0.709 (95% CI: 0.55–0.83), and 0.738 (95% CI: 0.58–0.85). Regarding mortality, the respective AUCs were 0.684 (95% CI: 0.57–0.78), 0.678 (95% CI: 0.56–0.77), and 0.749 (95% CI: 0.64–0.84). Regarding calibration, there was modest calibration in general, with higher degrees of calibration in the fully functional outcome model.
Conclusion
The cohort outcomes for mortality occurred at a rate higher than the risk predictions suggested using the logistic regression created by the SAHITs. Applying the externally trained model provided adequate discrimination and modest calibration, yet underestimated risk when applied to the intensive care cohort, reflected in the probability density function analysis. Using the SAHIT models in this cohort may result in underestimation of mortality for the individual patient, and the accuracy of the model is not sufficient for individual patient prediction. These results challenge the appropriateness of using admission-based models for dynamic ICU populations and highlight the urgent need for critical care–specific prognostic tools.
{"title":"Assessment of outcomes in postaneurysmal subarachnoid bleed patients admitted to the intensive care unit utilizing the subarachnoid haemorrhage international trialist clinicoradiological prediction model for dichotomised functional outcome and mortality","authors":"David Mogg MBBS, BSc, MMed , James Walsham MBChB, FCICM","doi":"10.1016/j.ccrj.2025.100126","DOIUrl":"10.1016/j.ccrj.2025.100126","url":null,"abstract":"<div><h3>Objective</h3><div>The objective of this study was to assess the Subarachnoid Haemorrhage International Trialist (SAHIT) prediction model in a tertiary adult intensive care unit (ICU) cohort when assessing patient outcomes against predicted outcomes, firstly by assessing the discrimination and validation of the model in the Princess Alexandra Hospital (PA) intensive care cohort and secondly comparing the predicted outcomes using the SAHIT model to the actual cohort outcomes using a Monte Carlo simulation.</div></div><div><h3>Methods</h3><div>Six logistic regression models designed by the SAHIT Collaboration Group were applied to the PA cohort considering early predictive factors such as clinical grade and treatment modality to predict the risk of both mortality and unfavourable outcome at 6 months according to the Glasgow Outcome Score. The six SAHIT logistic regression models were applied to a retrospectively collected cohort of aneurysmal subarachnoid patients who were admitted to the ICU, generating individual risk scores for mortality and poor functional outcome. Area under the curve (AUC) and calibration slope/intercept and Brier score were used to assess the strength of the model in interpreting the current data set. A Monte Carlo analysis was used to compare the actual mortality outcomes to the predicted outcomes to determine if the cohort performance was better or worse than predicted by the mortality model.</div></div><div><h3>Results</h3><div>Overall, the PA cohort actual mortality was higher than the predicted mortality rate based on the risk scores generated by the SAHIT models, demonstrated by Monte Carlo simulation using the SAHIT model risk scores. The core, neuroimaging, and full models for functional outcome produced AUCs of 0.719 (95% confidence interval [CI]: 0.55–0.84), 0.709 (95% CI: 0.55–0.83), and 0.738 (95% CI: 0.58–0.85). Regarding mortality, the respective AUCs were 0.684 (95% CI: 0.57–0.78), 0.678 (95% CI: 0.56–0.77), and 0.749 (95% CI: 0.64–0.84). Regarding calibration, there was modest calibration in general, with higher degrees of calibration in the fully functional outcome model.</div></div><div><h3>Conclusion</h3><div>The cohort outcomes for mortality occurred at a rate higher than the risk predictions suggested using the logistic regression created by the SAHITs. Applying the externally trained model provided adequate discrimination and modest calibration, yet underestimated risk when applied to the intensive care cohort, reflected in the probability density function analysis. Using the SAHIT models in this cohort may result in underestimation of mortality for the individual patient, and the accuracy of the model is not sufficient for individual patient prediction. These results challenge the appropriateness of using admission-based models for dynamic ICU populations and highlight the urgent need for critical care–specific prognostic tools.</div></div>","PeriodicalId":49215,"journal":{"name":"Critical Care and Resuscitation","volume":"27 4","pages":"Article 100126"},"PeriodicalIF":1.7,"publicationDate":"2025-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145365870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-22DOI: 10.1016/j.ccrj.2025.100121
Bianca B. Crichton BHealSc , Allie Eathorne MAppStat , Julieann Coombes PhD , Chloe Edwards RN, MPH , Patricia M. Falleni RN, MA , Kevin B. Laupland MD, PhD , Diane M. Mackle RN, PhD , Manoj Saxena MBBCh, PhD , Jackson Smeed-Tauroa BHlth , Kyle C. White MBBS, MPH , Paul J. Young MBChB, PhD , Therapeutic Warming Investigator Group
Objective
The objective of this study was to evaluate temperature profiles in patients treated for infections in the intensive care unit (ICU) to establish the number of patients who might be eligible for a clinical trial of therapeutic warming.
Design, setting, and participants
A prospective observational study was conducted in a Wellington ICU over a 3-month period in 2024 including consecutive adult unplanned admissions and excluding those with brain injury or seizures.
Main outcome measures
We screened 200 eligible patients. Our primary outcome was the proportion of all unplanned ICU admission episodes where patients were treated for infection within 14 days in the ICU. Patients treated for an infection were divided into four groups (≥38.3 °C, ≥37.5–38.2 °C, 36–37.4 °C, and <36 °C) using their most recent temperature prior to the first antimicrobial in the ICU (or at admission for patients already on antimicrobials). A key physiological/process measure was the fever deficit, defined as the number of degree-hours <38.3 °C within 24, 48, and 72 h.
Results
A total of 43.3% of unplanned ICU admissions resulted in treatment of infection within 14 days. A total of nine of 123 patients had a body temperature ≥38.3 °C (7.3%) when first treated for infection in the ICU, while 94 of 123 patients (76.4%) had a body temperature <37.5 °C. Fever deficits over 24-, 48-, and 72-h periods increased by decreasing body temperature group with a high proportion of hours spent with a body temperature <38.3 °C in all groups.
Conclusion
A large number of patients treated for infection in the ICU may be able to be included in a trial evaluating induced hyperthermia.
{"title":"Temperature profiles in adult intensive care unit patients treated for infection in a tertiary intensive care unit: A single-centre prospective observational cohort study","authors":"Bianca B. Crichton BHealSc , Allie Eathorne MAppStat , Julieann Coombes PhD , Chloe Edwards RN, MPH , Patricia M. Falleni RN, MA , Kevin B. Laupland MD, PhD , Diane M. Mackle RN, PhD , Manoj Saxena MBBCh, PhD , Jackson Smeed-Tauroa BHlth , Kyle C. White MBBS, MPH , Paul J. Young MBChB, PhD , Therapeutic Warming Investigator Group","doi":"10.1016/j.ccrj.2025.100121","DOIUrl":"10.1016/j.ccrj.2025.100121","url":null,"abstract":"<div><h3>Objective</h3><div>The objective of this study was to evaluate temperature profiles in patients treated for infections in the intensive care unit (ICU) to establish the number of patients who might be eligible for a clinical trial of therapeutic warming.</div></div><div><h3>Design, setting, and participants</h3><div>A prospective observational study was conducted in a Wellington ICU over a 3-month period in 2024 including consecutive adult unplanned admissions and excluding those with brain injury or seizures.</div></div><div><h3>Main outcome measures</h3><div>We screened 200 eligible patients. Our primary outcome was the proportion of all unplanned ICU admission episodes where patients were treated for infection within 14 days in the ICU. Patients treated for an infection were divided into four groups (≥38.3 °C, ≥37.5–38.2 °C, 36–37.4 °C, and <36 °C) using their most recent temperature prior to the first antimicrobial in the ICU (or at admission for patients already on antimicrobials). A key physiological/process measure was the fever deficit, defined as the number of degree-hours <38.3 °C within 24, 48, and 72 h.</div></div><div><h3>Results</h3><div>A total of 43.3% of unplanned ICU admissions resulted in treatment of infection within 14 days. A total of nine of 123 patients had a body temperature ≥38.3 °C (7.3%) when first treated for infection in the ICU, while 94 of 123 patients (76.4%) had a body temperature <37.5 °C. Fever deficits over 24-, 48-, and 72-h periods increased by decreasing body temperature group with a high proportion of hours spent with a body temperature <38.3 °C in all groups.</div></div><div><h3>Conclusion</h3><div>A large number of patients treated for infection in the ICU may be able to be included in a trial evaluating induced hyperthermia.</div></div>","PeriodicalId":49215,"journal":{"name":"Critical Care and Resuscitation","volume":"27 4","pages":"Article 100121"},"PeriodicalIF":1.7,"publicationDate":"2025-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145365871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-17DOI: 10.1016/j.ccrj.2025.100117
Georgia Peters BSc, MBBS (Hons), M Bioeth , Sharyn Milnes RN, GradCert CCN, GradCert Ed, GradDip AdEd, M Bioeth , Nicholas Simpson MBBS, FACEM, FCICM, PGDipEcho, GCHE , Olivia Gedye MBBS, FdnPallMed (cllinical) , Nima Kakho MBBS, FCICM , Charlie Corke MBBS, FCICM , Michael Bailey PhD, MSc, BSc (Hons) , Neil R. Orford MBBS, FCICM, FANZCA, PGDipEcho, PhD
Objective
Describe the association between the implementation of a shared decision-making (SDM) program and documentation of goals of care for critically ill patients with life-limiting illness (LLI).
Methods
A prospective longitudinal cohort study was conducted from 1st January 2015 to 30th September 2020 in an Australian tertiary teaching hospital. Adult patients with LLI admitted to the intensive care unit (ICU) were included. A SDM program consisting of communication training, a new goals of care form, and clinical support was implemented. The primary outcome was the proportion of patients with a documented SDM discussion. Secondary outcomes included patient treatment preferences and hospital utilisation parameters.
Results
A total of 1178 patients with LLI were admitted to the ICU during the study period and included in the study. Following the introduction of an SDM program, the proportion of patients with a documented SDM discussion increased from 22 % at baseline to a peak of 68 % at year five, then 60 % in year six of the study (adjusted odds ratio: 1.49, 95 % confidence interval: 1.38–1.60; p < 0.0001). Patients who had documented SDM were more likely to be older, female, frail, and have a prior advance care plan. SDM discussions resulted in higher rates of documented deterioration treatment preference plan (p < 0.0001), an increased ICU length of stay (3 vs. 2 days, p < 0.0001), referrals to palliative care services (p = 0.002), and a higher mortality rate. Time to death was significantly shorter in decedents with documented SDM compared to those without it (12 vs. 49 days, p < 0.0001).
Conclusion
The implementation of a comprehensive clinical communication training program was associated with increased documentation of shared decision-making discussions for patients in ICU with LLI, which corresponded with changes in patient treatment preferences and healthcare utilisation by decedents. Further research is required to understand the impact of these conversations from the perspective of patients and their families.
{"title":"Six years of a clinical communication intervention in shared decision-making to promote documentation of goals of care for critically ill patients with a life-limiting illness","authors":"Georgia Peters BSc, MBBS (Hons), M Bioeth , Sharyn Milnes RN, GradCert CCN, GradCert Ed, GradDip AdEd, M Bioeth , Nicholas Simpson MBBS, FACEM, FCICM, PGDipEcho, GCHE , Olivia Gedye MBBS, FdnPallMed (cllinical) , Nima Kakho MBBS, FCICM , Charlie Corke MBBS, FCICM , Michael Bailey PhD, MSc, BSc (Hons) , Neil R. Orford MBBS, FCICM, FANZCA, PGDipEcho, PhD","doi":"10.1016/j.ccrj.2025.100117","DOIUrl":"10.1016/j.ccrj.2025.100117","url":null,"abstract":"<div><h3>Objective</h3><div>Describe the association between the implementation of a shared decision-making (SDM) program and documentation of goals of care for critically ill patients with life-limiting illness (LLI).</div></div><div><h3>Methods</h3><div>A prospective longitudinal cohort study was conducted from 1st January 2015 to 30th September 2020 in an Australian tertiary teaching hospital. Adult patients with LLI admitted to the intensive care unit (ICU) were included. A SDM program consisting of communication training, a new goals of care form, and clinical support was implemented. The primary outcome was the proportion of patients with a documented SDM discussion. Secondary outcomes included patient treatment preferences and hospital utilisation parameters.</div></div><div><h3>Results</h3><div>A total of 1178 patients with LLI were admitted to the ICU during the study period and included in the study. Following the introduction of an SDM program, the proportion of patients with a documented SDM discussion increased from 22 % at baseline to a peak of 68 % at year five, then 60 % in year six of the study (adjusted odds ratio: 1.49, 95 % confidence interval: 1.38–1.60; p < 0.0001). Patients who had documented SDM were more likely to be older, female, frail, and have a prior advance care plan. SDM discussions resulted in higher rates of documented deterioration treatment preference plan (p < 0.0001), an increased ICU length of stay (3 vs. 2 days, p < 0.0001), referrals to palliative care services (p = 0.002), and a higher mortality rate. Time to death was significantly shorter in decedents with documented SDM compared to those without it (12 vs. 49 days, p < 0.0001).</div></div><div><h3>Conclusion</h3><div>The implementation of a comprehensive clinical communication training program was associated with increased documentation of shared decision-making discussions for patients in ICU with LLI, which corresponded with changes in patient treatment preferences and healthcare utilisation by decedents. Further research is required to understand the impact of these conversations from the perspective of patients and their families.</div></div>","PeriodicalId":49215,"journal":{"name":"Critical Care and Resuscitation","volume":"27 4","pages":"Article 100117"},"PeriodicalIF":1.7,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145324262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-17DOI: 10.1016/j.ccrj.2025.100133
Kristen S. Gibbons PhD , Renate Le Marsney MPH , Andrew Goodwin PhD , Rayna Reddy BSc , Patricia Gilholm PhD , David Pilcher MBBS, FCICM , Ben Gelbart MBBS, FRACP, FCICM, PhD , the Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG)
Objectives
The objective of this study was to assess data-related resources, infrastructure, and capabilities in Australia and New Zealand (ANZ) intensive care units (ICUs).
Design
Electronic multicentre survey was conducted.
Setting
ANZ ICUs between June and October 2024.
Participants
All ANZ ICUs contributing to the Australian and New Zealand Intensive Care Society Adult Patient Database and/or Australian and New Zealand Paediatric Intensive Care Registry were included in this study.
Interventions
There are none to declare.
Main outcome measures
The main outcome measures included types of medical records, digital data capture and research availability, digital enhancement plans, staffing, and research collaboration.
Results
Of 209 ICUs, 112 (54%) responded; 13 paediatric, 21 mixed, and 78 adult ICUs, with responses from all ANZ jurisdictions. Overall, 59% used paper records (5 paediatric and 61 mixed/adult), 28% digitised (7 paediatric and 24 mixed/adult), and 59% electronic health records (EHRs; 10 paediatric and 56 mixed/adult), with most EHRs introduced within the last decade (76%). In units with an EHR, 59% collected data secondly or minutely in the EHR and >75% collected EHR data on patient demographics, clinical notes, laboratory results, medications, fluids, bedside monitors, and respiratory support devices. Data Managers were employed within 45% of ICUs, with 96% able to extract data for audit and 92% for research. Respondents reported frustrations with delayed EHR implementation and limited data extraction mechanisms.
Conclusions
Substantial variability exists across ANZ ICUs in digital health adoption, data capture, and data management resources. Quantifying differences in digital information, improving data extraction, and building collaborative networks are key steps for supporting research and innovation across units.
{"title":"Building the future of ICU care: Is our digital foundation strong enough? A multicentre survey of Australian and New Zealand intensive care units","authors":"Kristen S. Gibbons PhD , Renate Le Marsney MPH , Andrew Goodwin PhD , Rayna Reddy BSc , Patricia Gilholm PhD , David Pilcher MBBS, FCICM , Ben Gelbart MBBS, FRACP, FCICM, PhD , the Australian and New Zealand Intensive Care Society Paediatric Study Group (ANZICS PSG)","doi":"10.1016/j.ccrj.2025.100133","DOIUrl":"10.1016/j.ccrj.2025.100133","url":null,"abstract":"<div><h3>Objectives</h3><div>The objective of this study was to assess data-related resources, infrastructure, and capabilities in Australia and New Zealand (ANZ) intensive care units (ICUs).</div></div><div><h3>Design</h3><div>Electronic multicentre survey was conducted.</div></div><div><h3>Setting</h3><div>ANZ ICUs between June and October 2024.</div></div><div><h3>Participants</h3><div>All ANZ ICUs contributing to the Australian and New Zealand Intensive Care Society Adult Patient Database and/or Australian and New Zealand Paediatric Intensive Care Registry were included in this study.</div></div><div><h3>Interventions</h3><div>There are none to declare.</div></div><div><h3>Main outcome measures</h3><div>The main outcome measures included types of medical records, digital data capture and research availability, digital enhancement plans, staffing, and research collaboration.</div></div><div><h3>Results</h3><div>Of 209 ICUs, 112 (54%) responded; 13 paediatric, 21 mixed, and 78 adult ICUs, with responses from all ANZ jurisdictions. Overall, 59% used paper records (5 paediatric and 61 mixed/adult), 28% digitised (7 paediatric and 24 mixed/adult), and 59% electronic health records (EHRs; 10 paediatric and 56 mixed/adult), with most EHRs introduced within the last decade (76%). In units with an EHR, 59% collected data secondly or minutely in the EHR and >75% collected EHR data on patient demographics, clinical notes, laboratory results, medications, fluids, bedside monitors, and respiratory support devices. Data Managers were employed within 45% of ICUs, with 96% able to extract data for audit and 92% for research. Respondents reported frustrations with delayed EHR implementation and limited data extraction mechanisms.</div></div><div><h3>Conclusions</h3><div>Substantial variability exists across ANZ ICUs in digital health adoption, data capture, and data management resources. Quantifying differences in digital information, improving data extraction, and building collaborative networks are key steps for supporting research and innovation across units.</div></div>","PeriodicalId":49215,"journal":{"name":"Critical Care and Resuscitation","volume":"27 4","pages":"Article 100133"},"PeriodicalIF":1.7,"publicationDate":"2025-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145324281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}