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Immediate loading of fixed prostheses in fully edentulous jaws - 1-year follow-up from a single-cohort retrospective study. 完全无牙颌中固定修复体的即时加载——单队列回顾性研究的1年随访。
Q1 Dentistry Pub Date : 2022-12-05 DOI: 10.3390/app122312427
G. Pantaleo, Alfonso Acerra, F. Giordano, Francesco D’Ambrosio, Michele Langone, M. Caggiano
PURPOSETo evaluate the clinical outcome of four to five implants immediately restored with metal-resin screw-retained cross-arch fixed prostheses in edentulous jaws 1 year after loading.MATERIALS AND METHODSIn total, 104 consecutive patients received four 11 × 4.5 mm implants with a torque superior to 35 Ncm. If one implant did not reach a torque superior to 35 Ncm a fifth implant was added. If two implants did not reach a torque superior to 35 Ncm, loading was postponed after 3 months. A total of 127 metal-resin screw-retained fixed prostheses (59 mandibular and 68 maxillary) were to be delivered within 3 days. Outcome measures, evaluated by the treating clinician, were: prosthesis and implant failures, as well as complications.RESULTSIn total, 549 implants were placed (195 immediate post-extractive implants). Twelve maxillary prostheses were delayed loaded, whereas all others were loaded immediately. One year after loading, six patients dropped out, 12 implants failed in eight patients (two patients lost three implants each), and 87 prostheses were remade in 68 patients, one because of three implant failures and then again in the recall programme (replaced twice), one because of tree implant failures and five prosthesis fractures, 10 because of prostheses fractures and 74 in a recall programme for prosthesis replacement. All patients were wearing the planned fixed prostheses at the end of the first year in function. Ninety-eight complications occurred in 66 patients, but all were successfully solved.CONCLUSIONSImmediately loaded cross-arch prostheses supported by four to five implants are a viable therapeutic option, if prostheses are made with resistant frameworks.
目的评价4 ~ 5例无牙颌金属树脂螺钉保留交叉弓固定修复体在装填1年后即刻修复的临床效果。材料与方法共104例患者连续接受4个11 × 4.5 mm扭矩大于35 Ncm的种植体。如果一个植入物没有达到超过35 Ncm的扭矩,则添加第五个植入物。如果两个植入物的扭矩不超过35 Ncm,则在3个月后推迟加载。3天内完成金属树脂固定假体127例(下颌骨59例,上颌68例)。治疗临床医生评估的结果是:假体和种植体失败,以及并发症。结果共放置种植体549个(即刻拔牙后种植体195个)。12个上颌假体延迟加载,其余全部立即加载。装填一年后,6名患者退出,8名患者中12个植入物失败(2名患者每人丢失3个植入物),68名患者中87个植入物被重新制作,1名患者因为3个植入物失败,然后在召回计划中再次更换(更换两次),1名患者因为3个植入物失败和5个假体骨折,10名患者因为假体骨折,74名患者在召回计划中更换假体。在第一年结束时,所有患者都佩戴了计划的固定假体。66例患者发生98例并发症,均成功解决。结论4 ~ 5个种植体支持即刻负荷的交叉弓义体是一种可行的治疗选择,如果义体采用耐药框架。
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引用次数: 13
Research in focus. 重点研究。
Q1 Dentistry Pub Date : 2021-05-01 DOI: 10.7748/phc.19.7.14.s24
H. Petersen
This section presents a brief review of articles on dental implants considered of special interest to readers, in order to encourage the development of research, the interest in data analysis and the attention to scientific publications. Your comments are welcome. Please contact Dr Michele Nieri at michelenieri@gmail.com.
本节简要回顾了读者特别感兴趣的关于种植牙的文章,以鼓励研究的发展、对数据分析的兴趣以及对科学出版物的关注。欢迎您的评论。请联系Michele Nieri博士michelenieri@gmail.com.
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引用次数: 739
Dental implants with internal versus external connections: 1-year post-loading results from a pragmatic multicenter randomised controlled trial. 牙种植体内连接与外连接:一项实用的多中心随机对照试验加载后1年的结果
Q1 Dentistry Pub Date : 2021-03-01 DOI: 10.36130/ctd.05.2020.02
M. Esposito, H. Maghaireh, R. Pistilli, M. G. Grusovin, Sang Taek Lee, F. Gualini, J. Yoo, J. Buti
PURPOSETo evaluate advantages and disadvantages of identical implants with internal or external connections.MATERIALS AND METHODSTwo hundred patients with any type of edentulism (single tooth, partial and total edentulism) requiring one implant-supported prosthesis were randomly allocated in two equal groups to receive either implants with an external connection (EC) or implants of the same type but with an internal connection (IC) (EZ Plus, MegaGen Implant, Gyeongbuk, South Korea) at seven centres. Due to slight differences in implant design/components, IC implants were platform switched while EC were not. Patients were followed for 1 year after initial loading. Outcome measures were prosthesis/implant failures, any complication, marginal bone level changes and clinician preference assessed by blinded outcome assessors.RESULTSOne hundred and two patients received 173 EC implants and 98 patients received 154 IC implants. Six patients dropped out with 11 EC implants and 3 patients with four IC implants, but all remaining patients were followed up to 1-year post-loading. Two centres did not provide any periapical radiographs. Two prostheses supported by EC implants and one supported by IC implants failed (P = 1.000, difference = -0.01, 95% CI: -0.05 to 0.04). Three EC implants failed in 3 patients versus two IC implants in 1 patient (P = 0.6227, difference = -0.02, 95% CI: -0.07 to 0.03). EC implants were affected by nine complications in 9 patients versus six complications of IC implants in 6 patients (P = 0.5988, difference = -0.02, 95% CI: -0.10 to 0.06). There were no statistically significant differences for prosthesis/implant failures and complications between the implant systems. One year after loading, there were no statistically significant differences in marginal bone level changes between the two groups (difference = 0.24, 95% CI: -0.01 to 0.50, P = 0.0629) and both groups lost bone from implant placement in a statistically significant manner: 0.98 mm for the EC implants and 0.85 mm for the IC implants. Five operators had no preference and two preferred IC implants.CONCLUSIONSWithin the limitations given by the difference in neck design and platform switching between EC and IC implants, preliminary short-term data (1-year post-loading) did not show any statistically significant differences between the two connection types, therefore clinicians could choose whichever one they preferred.
目的评估具有内部或外部连接的相同植入物的优点和缺点。材料和方法将200名任何类型的缺牙症(单牙、部分和全牙)患者随机分为两组,在七个中心接受具有外部连接(EC)或相同类型但具有内部连接(IC)的植入物(EZ Plus,MegaGen implant,Gyeongbuk,South Korea)。由于植入物设计/组件略有差异,IC植入物进行了平台切换,而EC则没有。患者在初次负荷后随访1年。结果指标包括假体/植入物失败、任何并发症、边缘骨水平变化和由盲法结果评估员评估的临床医生偏好。结果102例接受了173个EC植入物,98例接受了154个IC植入物。6名患者退出11个EC植入物,3名患者退出4个IC植入物,但所有剩余患者都进行了1年的负载后随访。两个中心没有提供任何根尖周射线照片。两个由EC植入物支撑的假体和一个由IC植入物支持的假体失败(P=1.000,差异=0.01,95%CI:0.05至0.04)。三个EC植入物在3名患者中失败,而两个IC植入物在1名患者中无效(P=0.6227,差异=0.02,95%CI:0.07至0.03)。EC植入物受9名患者并发症影响,而IC植入物受6名患者并发症的影响(P=0.5988,差异=-0.02,95%置信区间:-0.10至0.06)。植入系统之间的假体/植入物故障和并发症没有统计学上的显著差异。加载一年后,两组之间的边缘骨水平变化没有统计学上的显著差异(差异=0.24,95%CI:0.01至0.50,P=0.0629),并且两组在植入时均以统计学上显著的方式失去了骨:EC植入物为0.98 mm,IC植入物为0.85 mm。五名操作员没有偏好,两名操作员偏好IC植入物。结论在EC和IC植入物之间颈部设计和平台切换的差异所带来的局限性中,初步的短期数据(加载后1年)没有显示出两种连接类型之间有任何统计学上的显著差异,因此临床医生可以选择他们喜欢的连接类型。
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引用次数: 24
Research in focus. 重点研究。
Q1 Dentistry Pub Date : 2020-05-02 DOI: 10.7748/phc.20.10.14.s24
K. Davis
This section presents a brief review of articles on dental implants considered of special interest for the reader, in order to encourage the developing of research, the interest for data analysis and the attention to scientific publications. Your comments are welcome. Please contact Dr Michele Nieri at michelenieri@gmail.com.
本节简要回顾了读者特别感兴趣的关于种植牙的文章,以鼓励研究的发展,对数据分析的兴趣和对科学出版物的关注。欢迎你的评论。请通过michelenieri@gmail.com联系Michele Nieri博士。
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引用次数: 0
Immediate, early (6 weeks) and delayed loading (3 months) of single, partial and full fixed implant supported prostheses: 1-year post-loading data from a multicentre randomised controlled trial. 即刻、早期(6周)和延迟加载单个、部分和全部固定种植支撑假体(3个月):加载后1年的多中心随机对照试验数据。
Q1 Dentistry Pub Date : 2020-05-01 DOI: 10.36130/ctd.01.2019.04
Miltiadis Mitsias, Konstantinos D. Siormpas, Valeria Pistilli, Anna Trullenque-Eriksson, M. Esposito
PURPOSETo compare the clinical outcome of single, partial and complete fixed implant supported prostheses immediately loaded (within 48 h), early loaded at 6 weeks, and conventionally loaded at 3 months (delayed loading).MATERIALS AND METHODSA total of 54 patients (18 requiring single implants, 18 partial fixed prostheses, and 18 total fixed cross-arch prostheses) were randomised in equal numbers at two private practices to immediate loading (18 patients), early loading (18 patients), and conventional loading (18 patients) according to a parallel group design with three arms. To be immediately or early loaded, implants had to be inserted with a torque superior to 40 Ncm. Implants were initially loaded with provisional prostheses, replaced after 4 months by definitive ones. Outcome measures were prosthesis and implant failures, complications and peri-implant marginal bone levels.RESULTSTwo conventionally loaded patients rehabilitated with cross-arch fixed total prostheses dropped-out up to 1 year post-loading. No implant or prosthesis failed and three complications occurred, one in each loading group. Peri-implant marginal bone loss was 0.19 ± 0.44 mm at immediately loaded implants, 0.18 ± 0.66 mm at early loaded implants and 0.25 ± 0.28 mm at conventional loaded implants. There were no statistically significant differences in complications (P = 1.000) and bone loss (P = 0.806) between the three loading strategies.CONCLUSIONSAll loading strategies were highly successful and no differences could be observed for implant survival and complications when loading implants immediately, early or conventionally.
目的比较即刻加载(48小时内)、6周早期加载的单个、部分和完全固定植入物支持的假体的临床结果,材料和方法在两个私人诊所将54名患者(18名需要单植入物,18名部分固定假体,18名全固定交叉弓假体)随机分为即时加载(18名患者)、早期加载(18例患者)、,以及根据具有三个臂的平行组设计的常规装载(18名患者)。为了立即或尽早加载,植入物必须以超过40Ncm的扭矩插入。植入物最初装载临时假体,4个月后用最终假体替换。结果指标包括假体和植入物的失败、并发症和植入物周围的边缘骨水平。结果两名常规负荷的患者在负荷后1年内用交叉弓固定的全人工假体进行康复。没有植入物或假体失败,出现三种并发症,每组一种。即刻加载植入物的种植体周围边缘骨损失为0.19±0.44 mm,早期加载植入物为0.18±0.66 mm,常规加载植入物则为0.25±0.28 mm。三种负荷策略在并发症(P=1.000)和骨丢失(P=0.806)方面没有统计学上的显著差异。结论所有加载策略都非常成功,当立即、早期或常规加载植入物时,植入物的存活率和并发症没有差异。
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引用次数: 10
The role of dental implant abutment design on the aesthetic outcome: preliminary 3-month post-loading results from a multicentre split-mouth randomised controlled trial comparing two different abutment designs. 牙种植体基台设计对美学结果的作用:多中心裂口随机对照试验比较两种不同基台设计的初步加载后3个月结果。
Q1 Dentistry Pub Date : 2018-01-01
Marco Esposito, Daniele Cardaropoli, Luca Gobbato, Fabio Scutellà, Andrea Fabianelli, Saverio Mascellani, Gianluca Delli Ficorelli, Fabio Mazzocco, Luca Sbricoli, Anna Trullenque-Eriksson

Purpose: To evaluate whether there are aesthetic and clinical benefits to using a newly designed abutment (Curvomax), over a conventional control abutment (GingiHue).

Materials and methods: A total of 49 patients, who required at least two implants, had two sites randomised according to a split-mouth design to receive one abutment of each type at seven different centres. The time of loading (immediate, early or delayed) and of prosthesis (provisional crowns of fixed prosthesis) was decided by the clinicians, but they had to restore both implants in a similar way. Provisional prostheses were replaced by definitive ones 3 months after initial loading, when the follow-up for the initial part of this study was completed. Outcome measures were: prosthesis failures, implant failures, complications, pink esthetic score (PES), peri-implant marginal bone level changes, and patient preference.

Results: In total, 49 Curvomax and 49 GingiHue abutments were delivered. Two patients dropped out. No implant failure, prosthesis failure or complication was reported. There were no differences at 3 months post-loading for PES (difference = -0.15, 95% CI -0.55 to 0.25; P (paired t test) = 0.443) and marginal bone level changes (difference = -0.02 mm, 95% CI -0.20 to 0.16; P (paired t test) = 0.817). The majority of the patients (30) had no preference regarding the two abutment designs; 11 patients preferred the Curvomax, while five patients preferred the GingiHue abutments (P (McNemar test) = 0.210).

Conclusions: The preliminary results of the comparison between two different abutment designs did not disclose any statistically significant differences between the evaluated abutments. However the large number of missing radiographs and clinical pictures casts doubt on the reliability of the results. Longer follow-ups of wider patient populations are needed to better understand whether there is an effective advantage with one of the two abutment designs.

目的:评估使用新设计的基台(Curvomax)与传统对照基台(GingiHue)相比是否具有美学和临床效益。材料和方法:共有49名患者需要至少两个种植体,根据裂口设计随机选择两个地点,在7个不同的中心接受每种类型的一个基台。加载时间(即刻、提前或延迟)和假体(固定假体的临时冠)由临床医生决定,但他们必须以相似的方式修复两种种植体。当本研究初始部分的随访完成后,临时假体在首次装载后3个月被确定假体所取代。结果测量:假体失败、种植体失败、并发症、粉红色美学评分(PES)、种植体周围边缘骨水平变化和患者偏好。结果:共交付Curvomax基牙49枚,GingiHue基牙49枚。两个病人退出了。无种植体失败、假体失败或并发症报道。PES加载后3个月无差异(差异= -0.15,95% CI -0.55 ~ 0.25;P(配对t检验)= 0.443)和边缘骨水平变化(差异= -0.02 mm, 95% CI -0.20 ~ 0.16;配对t检验= 0.817)。大多数患者(30例)对两种基台设计没有偏好;11例患者首选Curvomax, 5例患者首选GingiHue基台(P (McNemar检验)= 0.210)。结论:两种不同基台设计的初步比较结果显示,所评估的基台之间没有统计学上的显著差异。然而,大量缺失的x线片和临床图片使结果的可靠性受到怀疑。需要对更广泛的患者群体进行更长时间的随访,以更好地了解两种基台设计中的一种是否具有有效的优势。
{"title":"The role of dental implant abutment design on the aesthetic outcome: preliminary 3-month post-loading results from a multicentre split-mouth randomised controlled trial comparing two different abutment designs.","authors":"Marco Esposito,&nbsp;Daniele Cardaropoli,&nbsp;Luca Gobbato,&nbsp;Fabio Scutellà,&nbsp;Andrea Fabianelli,&nbsp;Saverio Mascellani,&nbsp;Gianluca Delli Ficorelli,&nbsp;Fabio Mazzocco,&nbsp;Luca Sbricoli,&nbsp;Anna Trullenque-Eriksson","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate whether there are aesthetic and clinical benefits to using a newly designed abutment (Curvomax), over a conventional control abutment (GingiHue).</p><p><strong>Materials and methods: </strong>A total of 49 patients, who required at least two implants, had two sites randomised according to a split-mouth design to receive one abutment of each type at seven different centres. The time of loading (immediate, early or delayed) and of prosthesis (provisional crowns of fixed prosthesis) was decided by the clinicians, but they had to restore both implants in a similar way. Provisional prostheses were replaced by definitive ones 3 months after initial loading, when the follow-up for the initial part of this study was completed. Outcome measures were: prosthesis failures, implant failures, complications, pink esthetic score (PES), peri-implant marginal bone level changes, and patient preference.</p><p><strong>Results: </strong>In total, 49 Curvomax and 49 GingiHue abutments were delivered. Two patients dropped out. No implant failure, prosthesis failure or complication was reported. There were no differences at 3 months post-loading for PES (difference = -0.15, 95% CI -0.55 to 0.25; P (paired t test) = 0.443) and marginal bone level changes (difference = -0.02 mm, 95% CI -0.20 to 0.16; P (paired t test) = 0.817). The majority of the patients (30) had no preference regarding the two abutment designs; 11 patients preferred the Curvomax, while five patients preferred the GingiHue abutments (P (McNemar test) = 0.210).</p><p><strong>Conclusions: </strong>The preliminary results of the comparison between two different abutment designs did not disclose any statistically significant differences between the evaluated abutments. However the large number of missing radiographs and clinical pictures casts doubt on the reliability of the results. Longer follow-ups of wider patient populations are needed to better understand whether there is an effective advantage with one of the two abutment designs.</p>","PeriodicalId":49259,"journal":{"name":"European Journal of Oral Implantology","volume":"11 1","pages":"77-87"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35929001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Brain abscess following dental implant placement via crestal sinus lift - a case report. 牙种植体经嵴窦提升后脑脓肿1例报告。
Q1 Dentistry Pub Date : 2018-01-01
Yifat Manor, Adi A Garfunkel

Purpose: To describe a rare case of odontogenic brain abscess.

Materials and methods: A healthy, 35-year-old male had two dental implants placed in a simultaneously augmented maxillary sinus. One implant failed and the patient developed a maxillary sinusitis that failed to improve following antibiotic treatment at home. The neglected sinus infection led to formation of a brain abscess. The patient was hospitalised only when he had pan sinusitis with neurological signs. Symptoms were headache attacks, a subfebrile fever and a purulent secretion from the left nostril. The osteomeatal complex was blocked, the maxillary sinus was filled with pus and the Schneiderian membrane thickened. The patient was treated with intravenous antibiotic treatment. Computerised tomography (CT) and magnetic resonance imaging (MRI) scans and functional endoscopic sinus surgery (FESS), were implemented. When his conditions worsened, the patient underwent a left frontal mini craniotomy.

Results: Following the craniotomy and antibiotic treatment, there was a gradual resolution and the patient was dismissed after 2 months in hospital with no neurological deficit or signs of sinusitis.

Conclusions: Maxillary sinusitis following dental implant insertion and concomitant maxillary sinus elevation should be treated immediately and thoroughly since untreated sinusitis may cause life-threatening situations such as a brain abscess. In case of severe infection, clinicians should refer immediately the patient to hospital specialists.

目的:报告一例罕见的牙源性脑脓肿。材料和方法:一名健康的35岁男性,在上颌窦同时植入两颗种植体。一次种植失败,患者发展为上颌鼻窦炎,在家中抗生素治疗后未能改善。被忽视的鼻窦感染导致脑脓肿的形成。患者仅在出现泛鼻窦炎并伴有神经症状时才住院。症状为头痛发作、低热和左鼻孔脓性分泌物。骨突复合体阻塞,上颌窦充满脓液,施耐德膜增厚。病人接受静脉抗生素治疗。实施计算机断层扫描(CT)和磁共振成像(MRI)扫描和功能性内窥镜鼻窦手术(FESS)。当病情恶化时,患者接受了左额叶小开颅手术。结果:经开颅和抗生素治疗后,病情逐渐好转,住院2个月后出院,无神经功能缺损或鼻窦炎症状。结论:上颌鼻窦炎后植牙植入和伴随上颌窦抬高应立即彻底治疗,因为未经治疗的鼻窦炎可能导致危及生命的情况,如脑脓肿。在严重感染的情况下,临床医生应立即将患者转介给医院专家。
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引用次数: 0
Immediately loaded zygomatic implants vs conventional dental implants in augmented atrophic maxillae: 4 months post-loading results from a multicentre randomised controlled trial. 一项多中心随机对照试验:即刻加载颧骨种植体与常规牙种植体在增强型萎缩性上颌的对比
Q1 Dentistry Pub Date : 2018-01-01
Marco Esposito, Rubén Davó, Carlos Marti-Pages, Ada Ferrer-Fuertes, Carlo Barausse, Roberto Pistilli, Daniela Rita Ippolito, Pietro Felice

Purpose: To compare the clinical outcome of immediately loaded cross-arch maxillary prostheses supported by zygomatic implants vs conventional implants placed in augmented bone.

Materials and methods: A total of 71 edentulous patients with severely atrophic maxillas, who did not have sufficient bone volume to place dental implants or when it was possible to place only two implants in the front area (minimal diameter 3.5 mm and length of 8 mm) and less than 4.0 mm of bone height subantrally, were randomised according to a parallel group design. They (35 patients) received zygomatic implants to be loaded immediately vs grafting with a xenograft, followed, after 6 months of graft consolidation, by the placement of six to eight conventional dental implants, submerged for 4 months (36 patients). To be loaded immediately, zygomatic implants had to be inserted with an insertion torque superior to 40 Ncm. Screw-retained, metal-reinforced, acrylic provisional prostheses were provided to be replaced by definitive Procera Implant Bridge Titanium prostheses (Nobel Biocare, Göteborg, Sweden) with ceramic or acrylic veneer materials 4 months after initial loading. Outcome measures were: prosthesis, implant and augmentation failures, any complications, quality of life (OHIP-14), the number of days that patients experienced total or partial impaired activity, time to function, and number of dental visits, assessed by independent assessors. Patients were followed up to 4 months after loading.

Results: No augmentation procedure failed. Three patients dropped out from the augmentation group. Six prostheses could not be delivered or failed in the augmentation group vs one prosthesis in the zygomatic group, the difference being statistically significant (difference in proportions = 15.32%; P = 0.04; 95% CI: 0.23 to 31.7). Eight patients lost 35 implants in the augmentation group vs three implants in one patient from the zygomatic group, the difference being statistically significant (difference in proportions = 21.38%; P = 0.001; 95% CI: 3.53 to 39.61). In total, 14 augmented patients were affected by 20 complications vs 26 zygomatic patients (35 complications), the difference being statistically significant (difference in proportions = 31.87%; P = 0.008; 95% CI: 6.48 to 53.37). The OHIP-14 score was 3.68 ± 5.41 for augmented patients and 4.97 ± 5.79 for zygomatic patients, with no statistically significant differences between groups (mean difference = 1.29; 95%CI -1.60 to 4.18; P = 0.439). Both groups had significantly improved OHIP-14 scores from before rehabilitation (P < 0.001 for both augmented and zygomatic patients). The number of days of total infirmity was, on average, 7.42 ± 3.17 for the augmented group and 7.17 ± 1.96 for the zygomatic group, the difference not being statistically significant (mean difference = -0.25; 95% CI: -1.52 to 1.02; P = 0.692). Days of partial infirmity were on avera

目的:比较颧骨种植体与常规种植体支撑的即刻负荷交叉弓上颌假体的临床效果。材料和方法:采用平行组设计,随机选取71例上颌严重萎缩无牙患者,这些患者没有足够的骨容量放置种植体或只能在前部放置两个种植体(最小直径3.5 mm,长度8 mm),底部骨高小于4.0 mm。他们(35名患者)接受颧骨种植体立即加载与异种移植物移植,随后,在移植物巩固6个月后,放置6至8个传统牙科种植体,浸泡4个月(36名患者)。为了立即加载,颧骨植入物必须以大于40 Ncm的插入扭矩插入。螺钉保留,金属增强,丙烯酸临时假体,在首次加载后4个月用陶瓷或丙烯酸贴面材料的最终Procera种植桥钛假体(Nobel Biocare, Göteborg,瑞典)代替。结果测量是:由独立评估者评估的假体、种植体和增强体失败、任何并发症、生活质量(OHIP-14)、患者经历全部或部分活动受损的天数、功能恢复时间和牙科就诊次数。患者随访至装药后4个月。结果:无隆胸手术失败。三名患者退出了强化组。隆胸组6个假体不能交付或失败,颧组1个假体,差异有统计学意义(比例差异= 15.32%;P = 0.04;95% CI: 0.23 ~ 31.7)。隆胸组8例患者丢失35个假体,颧骨组1例患者丢失3个假体,差异有统计学意义(比例差异= 21.38%;P = 0.001;95% CI: 3.53 ~ 39.61)。增强侧14例患者共发生并发症20例,颧侧26例患者共发生并发症35例,差异有统计学意义(比例差异= 31.87%;P = 0.008;95% CI: 6.48 ~ 53.37)。增强组OHIP-14评分为3.68±5.41分,颧骨组为4.97±5.79分,组间差异无统计学意义(平均差异= 1.29;95%CI -1.60 - 4.18;P = 0.439)。两组患者的OHIP-14评分均较康复前显著改善(增强型和颧骨型患者均P < 0.001)。总虚弱天数,增强组平均为7.42±3.17天,颧骨组平均为7.17±1.96天,差异无统计学意义(平均差异= -0.25;95% CI: -1.52 ~ 1.02;P = 0.692)。增强组局部虚弱天数平均为14.24±4.64天,颧骨组局部虚弱天数平均为12.17±3.82天,差异有统计学意义(平均差异= -2.07;95% CI: -4.12 ~ -0.02;P = 0.048)。增强型患者植入功能性假体的平均天数为444.32±207.86天,颧骨型患者为1.34±2.27天,差异有统计学意义(平均差异= -442.9;95% CI: -513.10 ~ -372.86;P < 0.001)。颧突患者平均就诊次数为12.58±5.21次,颧突患者平均就诊次数为16.79±10.88次,差异无统计学意义(平均差异= -4.21;95% CI -8.48 ~ 0.06;P = 0.053)。结论:加载后4个月的初步数据表明,与隆胸和常规加载牙种植体相比,颧种植体在统计学上显著减少了假体(1例比6例)和种植体失败(1例丢失3个种植体,8例丢失35个种植体)以及功能加载所需的时间(1.3天比444.3天)。尽管颧骨种植体出现了更多的并发症,这些并发症可以自行解决或处理,但事实证明,颧骨种植体是治疗严重颌骨萎缩的一种较好的康复方式。要证实或质疑这些初步结果,长期数据是必不可少的。利益冲突声明:本研究最初由植入物制造商Nobel Biocare提供支持,研究中使用的临时和最终假体组件免费提供给患者。然而,在任何结果公布之前,诺贝尔生物保健公司撤回了资金支持,招聘不得不停止。Tecnoss (Giaveno, Torino, Italy)捐赠了骨替代物和膜,而Global D (briignais, France)捐赠了骨合成螺钉。数据所有权归作者所有,制造商绝不干涉结果的发表。
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引用次数: 0
Research in focus. 重点研究。
Q1 Dentistry Pub Date : 2018-01-01

This section presents a brief review of articles on dental implants considered of special interest for the reader, in order to encourage the development of research, the interest for data analysis and the attention to scientific publications. Your comments are welcome. Please contact Dr Michele Nieri at michelenieri@gmail.com.

本节简要回顾了读者特别感兴趣的关于种植牙的文章,以鼓励研究的发展,对数据分析的兴趣和对科学出版物的关注。欢迎你的评论。请通过michelenieri@gmail.com联系Michele Nieri博士。
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引用次数: 0
Posterior atrophic jaws rehabilitated with prostheses supported by 5 × 5 mm implants with a nanostructured calcium-incorporated titanium surface or by longer implants in augmented bone. 3-year results from a randomised controlled trial. 采用纳米结构含钙钛表面的5 × 5 mm种植体或增强型骨长种植体修复后萎缩颌骨。3年的随机对照试验结果。
Q1 Dentistry Pub Date : 2018-01-01
Giorgio Gastaldi, Pietro Felice, Valeria Pistilli, Carlo Barausse, Daniela Rita Ippolito, Marco Esposito

Purpose: To evaluate whether 5.0 × 5.0 mm dental implants with a novel nanostructured calcium-incorporated titanium surface could be an alternative to implants of at least 10.0 mm long placed in bone augmented with bone substitutes in posterior atrophic jaws.

Materials and methods: Forty patients with atrophic posterior (premolar and molar areas) mandibles with 5.0 mm to 7.0 mm bone height above the mandibular canal, and 40 patients with atrophic maxillas with 4.0 mm to 6.0 mm below the maxillary sinus, were randomised according to a parallel group design to receive between one and three 5.0 mm implants or one to three at least 10.0 mm-long implants in augmented bone at two centres. All implants had a diameter of 5.0 mm. Mandibles were vertically augmented with interpositional bovine bone blocks covered with resorbable barriers. Implants were placed after 4 months. Maxillary sinuses were augmented with particulated porcine bone via a lateral window covered with resorbable barriers, and implants were placed simultaneously. All implants were submerged and loaded after 4 months with provisional prostheses. Four months later, definitive screw-retained or provisionally cement metal-ceramic or zirconia prostheses were delivered. Patients were followed to 3 years post-loading and the outcome measures were: prosthesis and implant failures, any complication, and peri-implant marginal bone level changes.

Results: Seven patients dropped out before the 3-year evaluation (two short mandibles, one short maxilla, two augmented mandibles and two augmented maxillae). In mandibles, two grafted patients were not prosthetically rehabilitated because of multiple complications and two implants failed in the same patient (the second was a replacement implant) vs one patient who lost a short implant and crown 2 years after loading. In maxillas one short implant failed with its provisional crown 3 months post-loading. There were no statistically significant differences in prostheses (difference in proportion = 0.001; 95% CI: -0.12 to 0.13; P = 1.000) and implant failures (difference in proportion = 0.00; 95% CI: -0.13 to 0.13; P = 1.000) up to 3 years after loading. Significantly, more complications occurred at mandibular grafted sites: 17 augmented patients were affected by complications vs eight patients treated with short implants in mandibles (difference in proportion = 0.43; 95% CI: 0.13 to 0.64; P = 0.008). In the maxilla, six sinus-lifted patients vs two patients treated with short implants were affected by complications; the difference not being statistically significant (difference in proportion = 0.21; 95% CI: -0.05 to 0.45; P = 0.232). Patients with mandibular short implants lost on average 1.10 mm of peri-implant bone at 3 years and patients with 10.0 mm or longer mandibular implants lost 1.39 mm. Patients with maxillary short implants lost on average 1.04 mm of peri-implant bone at 3 years and

目的:评估具有新型纳米结构钙钛表面的5.0 × 5.0 mm牙种植体是否可以替代放置在后萎缩颌骨增骨材料中至少10.0 mm长的种植体。材料和方法:40例下颌后(前磨牙和磨牙区)萎缩患者,下颌管以上骨高度5.0 mm至7.0 mm,以及40例上颌窦以下4.0 mm至6.0 mm的萎缩患者,根据平行组设计随机分组,在两个中心接受1至3个5.0 mm种植体或1至3个至少10.0 mm长的种植体。所有种植体直径均为5.0 mm。下颌骨用覆盖可吸收屏障的牛骨块垂直增强。4个月后植入。上颌窦通过覆盖可吸收屏障的侧窗用颗粒状猪骨增强,同时放置种植体。所有种植体在4个月后浸入水中并装载临时假体。4个月后,提供固定螺钉或临时水泥金属陶瓷或氧化锆假体。对患者进行加载后3年的随访,结果测量是:假体和种植体失败,任何并发症,种植体周围边缘骨水平变化。结果:7例患者在3年评估前退出(2例短下颌骨,1例短上颌骨,2例增长下颌骨,2例增长上颌骨)。在下颌骨,由于多种并发症,两名移植患者未能修复,同一患者中有两名种植体失败(第二名是替代种植体),而一名患者在装填后2年失去了短种植体和冠。上颌1例短种植失败,其临时冠在装填后3个月失效。两组假体间差异无统计学意义(比例差异= 0.001;95% CI: -0.12 ~ 0.13;P = 1.000)和种植体失败(比例差异= 0.00;95% CI: -0.13 ~ 0.13;P = 1.000),加载后最长可达3年。值得注意的是,下颌骨移植部位出现了更多的并发症:17例增加的患者出现了并发症,而8例使用了短种植体的患者出现了并发症(比例差异= 0.43;95% CI: 0.13 ~ 0.64;P = 0.008)。在上颌骨,6例鼻窦提升患者和2例短种植体患者出现并发症;差异无统计学意义(比例差异= 0.21;95% CI: -0.05 ~ 0.45;P = 0.232)。下颌短种植体患者3年平均损失1.10 mm种植体周围骨,10.0 mm或更长种植体患者3年平均损失1.39 mm。上颌种植体较短的患者在3年时平均损失了1.04 mm的种植体周围骨,而上颌种植体长度为10 mm或更长的患者损失了1.43 mm。上颌较长的种植体在装填后3年内比较短的种植体骨质流失更大(平均差:-0.39 mm;95% CI: -0.70 ~ -0.07 mm;P = 0.017)和下颌骨(平均差异:-0.29 mm;95% CI: -0.53 ~ -0.05 mm;P = 0.020)。结论:加载后3年,5.0 mm × 5.0 mm种植体与放置在增强骨上的较长种植体的效果相似。短种植体可能是一个更好的选择,特别是在后下颌骨,因为治疗更快,更便宜,发病率更低。然而,在提出可靠的建议之前,需要5至10年的加载后数据。
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European Journal of Oral Implantology
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