Pub Date : 2025-12-01Epub Date: 2025-02-11DOI: 10.1055/a-2479-7946
Sophie Dassen, Loes Monen, Guid Oei, Massimo Mischi, Judith van Laar
{"title":"Reply to Letter to the editor: Safety of contrast-enhanced ultrasound using microbubbles in human pregnancy: A scoping review.","authors":"Sophie Dassen, Loes Monen, Guid Oei, Massimo Mischi, Judith van Laar","doi":"10.1055/a-2479-7946","DOIUrl":"10.1055/a-2479-7946","url":null,"abstract":"","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"616"},"PeriodicalIF":2.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143400244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01Epub Date: 2025-07-23DOI: 10.1055/a-2664-6541
Christian B Laursen, Gabriele Via, Damien Basille, Rahul Bhatnagar, Christian Jenssen, Lars Konge, Silvia Mongodi, Pia Iben Pietersen, Helmut Prosch, Najib M Rahman, Paul S Sidhu, Matthias Wüstner, Caroline Ewertsen
A wide range of medical specialists increasingly use thoracic ultrasound and transthoracic ultrasound-guided interventions in their clinical practice. To ensure high quality and standardized practice across specialties, this position paper of the European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB) describes the training requirements for thoracic ultrasound. The recommendations follow the three EFSUMB competency levels for medical ultrasound practice. Level 1 describes the skills required to perform basic thoracic ultrasound examinations and basic interventions independently, level 2 includes more advanced transthoracic ultrasound imaging and guided interventions, while level 3 involves the practice of high-level thoracic ultrasound and the use of advanced technologies. Previously, a predefined minimum number of ultrasound examinations was used to determine competence, but in recent years, a general shift towards competency-based training and assessment has been implemented. For each EFSUMB level, we outline the theoretical knowledge and practical skills needed for clinical practice.
{"title":"Thoracic Ultrasound - EFSUMB Training Recommendations - a Position Paper.","authors":"Christian B Laursen, Gabriele Via, Damien Basille, Rahul Bhatnagar, Christian Jenssen, Lars Konge, Silvia Mongodi, Pia Iben Pietersen, Helmut Prosch, Najib M Rahman, Paul S Sidhu, Matthias Wüstner, Caroline Ewertsen","doi":"10.1055/a-2664-6541","DOIUrl":"10.1055/a-2664-6541","url":null,"abstract":"<p><p>A wide range of medical specialists increasingly use thoracic ultrasound and transthoracic ultrasound-guided interventions in their clinical practice. To ensure high quality and standardized practice across specialties, this position paper of the European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB) describes the training requirements for thoracic ultrasound. The recommendations follow the three EFSUMB competency levels for medical ultrasound practice. Level 1 describes the skills required to perform basic thoracic ultrasound examinations and basic interventions independently, level 2 includes more advanced transthoracic ultrasound imaging and guided interventions, while level 3 involves the practice of high-level thoracic ultrasound and the use of advanced technologies. Previously, a predefined minimum number of ultrasound examinations was used to determine competence, but in recent years, a general shift towards competency-based training and assessment has been implemented. For each EFSUMB level, we outline the theoretical knowledge and practical skills needed for clinical practice.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"560-567"},"PeriodicalIF":2.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144700206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01Epub Date: 2024-09-25DOI: 10.1055/a-2421-8319
Metin Cetiner, Selin Kavuk, Ilja Finkelberg, Martin Kreuzer, Christine Okorn, Benas Prusinskas, Felix Schiepek, Johannes Jägers, Lars Pape, Anja Büscher
Ultrasound (US) is the preferred imaging modality in pediatrics for diagnostic and therapeutic issues. The absence of radiation and the constant on-site accessibility make it the ideal tool for children. However, despite remarkable technical advances in resolution and applicability, many sophisticated medical questions still require profound expertise on the part of the examiner, thus often hampering fast decisions particularly outside regular working hours.This single-center study, at a university children's hospital evaluated the use of US during emergency service. A four-week documentation period was followed by a subsequent eight-week supervision period with live supervision availability on demand guided by a remote US expert. The demand for expert support, diagnosis, grading of urgency, duration and success of examination, and satisfaction of both examiners were analyzed.108 patients (mean age 9.7 years) were included. In 38% of cases, US was supervised on demand with a definite diagnosis in 92.6% of cases (25/27). Image quality and technical performance were graded sufficient in 100% of cases. Supervised compared to non-supervised US examinations were prolonged (14.4 min vs. 7.1 min, p<0.001), were more prevalent within the first 24 h in the hospital (70% vs. 56.8%, p=0.06), and were classified more frequently as emergency (22.2% vs. 2.3%; p=0.015). All participants classified the availability of US supervision as decisively helpful.Remote live supervised pediatric US was feasible and effective. It combined timely, high-quality diagnostics even in the case of challenging medical questions with simultaneous US training.
目的:超声波(US)是儿科诊断和治疗问题的首选成像方式。它没有辐射,可随时随地进行检查,是儿童理想的检查工具。然而,尽管在分辨率和适用性方面取得了显著的技术进步,但许多复杂的医学问题仍然需要检查人员具备深厚的专业知识,这往往妨碍了在正常工作时间以外做出快速决定:这项单中心研究在一所大学儿童医院进行,评估了急诊服务中使用 US 的情况。在为期四周的记录期之后是为期八周的督导期,由远程美国专家根据需求提供现场督导。对专家支持需求、诊断、紧急程度分级、检查持续时间和成功率以及双方检查人员的满意度进行了分析:结果:共纳入 108 名患者(平均年龄 9.7 岁)。在 38% 的病例中,按需进行了超声波检查,92.6% 的病例(25/27)得到了明确诊断。图像质量和技术性能100%达标。与非监督下的 US 检查相比,监督下的 US 检查时间更长(14.4 分钟对 7.1 分钟,p 结论:远程实时监督儿科 US 是可行且有效的。它将及时、高质量地诊断具有挑战性的医学问题与同时进行的 US 培训相结合。关键:儿科超声波(US)是诊断和治疗问题的理想工具,其优点是无辐射、无时间限制。尽管在成像和应用方面存在着巨大的技术缺陷,但这并不妨碍我们对更复杂的问题有更深入的了解,这也是我们进行定期诊断(尤其是在 Notdienst)的原因。材料和方法:在一所大学的幼儿园开展了一项针对 Notdienst 的美国调查的统一研究。在为期 4 个月的调查阶段之后,进行了为期 8 个月的监督阶段,并由一名美国专家进行现场监督。分析了对教师指导的影响、诊断结果、工作效率、工作时间、成功率以及研究人员的满意度。结果:108 名儿童(年龄约 9.7 岁)接受了治疗。38%的美国调查是在现场监督下进行的,其中92.6%(25/27)的儿童得到了诊断。图像质量和技术应用始终如一。监督检查时间更长(14.4 分钟 vs. 7.1 分钟,p
{"title":"Remote out-of-hours ultrasound live supervision in pediatrics - improvement of diagnostics and training.","authors":"Metin Cetiner, Selin Kavuk, Ilja Finkelberg, Martin Kreuzer, Christine Okorn, Benas Prusinskas, Felix Schiepek, Johannes Jägers, Lars Pape, Anja Büscher","doi":"10.1055/a-2421-8319","DOIUrl":"10.1055/a-2421-8319","url":null,"abstract":"<p><p>Ultrasound (US) is the preferred imaging modality in pediatrics for diagnostic and therapeutic issues. The absence of radiation and the constant on-site accessibility make it the ideal tool for children. However, despite remarkable technical advances in resolution and applicability, many sophisticated medical questions still require profound expertise on the part of the examiner, thus often hampering fast decisions particularly outside regular working hours.This single-center study, at a university children's hospital evaluated the use of US during emergency service. A four-week documentation period was followed by a subsequent eight-week supervision period with live supervision availability on demand guided by a remote US expert. The demand for expert support, diagnosis, grading of urgency, duration and success of examination, and satisfaction of both examiners were analyzed.108 patients (mean age 9.7 years) were included. In 38% of cases, US was supervised on demand with a definite diagnosis in 92.6% of cases (25/27). Image quality and technical performance were graded sufficient in 100% of cases. Supervised compared to non-supervised US examinations were prolonged (14.4 min vs. 7.1 min, p<0.001), were more prevalent within the first 24 h in the hospital (70% vs. 56.8%, p=0.06), and were classified more frequently as emergency (22.2% vs. 2.3%; p=0.015). All participants classified the availability of US supervision as decisively helpful.Remote live supervised pediatric US was feasible and effective. It combined timely, high-quality diagnostics even in the case of challenging medical questions with simultaneous US training.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"594-602"},"PeriodicalIF":2.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12700712/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142331003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01Epub Date: 2025-09-08DOI: 10.1055/a-2620-4784
Ingo Gottschalk, Tina Menzel, Christoph Berg
Approximately 0.8 % of all children are born with heart defects, with the prenatal incidence naturally being even higher. Among all congenital heart defects (CHD), conotruncal anomalies are the most common critical heart defects - after ventricular and atrial septal defects. Conotruncal anomalies are anomalies of the infundibulum (conus arteriosus) and great vessels (truncus arteriosus). These anomalies predominantly affect the right ventricular outflow tract and account for about 25-30 % of all CHD cases. Based on their incidence and clinical relevance, this article describes perimembranous ventricular septal defects (VSD), tetralogy of Fallot (TOF), pulmonary atresia with VSD (PAVSD), transposition of the great arteries (TGA), and the less common double outlet right ventricle (DORV) and truncus arteriosus communis (TAC).Conotruncal anomalies are usually associated with a normal 4-chamber view, so the prenatal detection rate during prenatal care tends to be low. However, because undetected conotruncal anomalies have high rates of postnatal mortality and morbidity, in accordance with internationally recommended policies, the foetal heart should always be examined systematically and segmentally in different sectional planes, including the outflow tract and in combination with the color Doppler, to achieve a higher detection rate. This article provides an overview of prenatal sonographic diagnosis of conotruncal anomalies based on extensive imaging material.
{"title":"Conotruncal Anomalies of the Fetus.","authors":"Ingo Gottschalk, Tina Menzel, Christoph Berg","doi":"10.1055/a-2620-4784","DOIUrl":"10.1055/a-2620-4784","url":null,"abstract":"<p><p>Approximately 0.8 % of all children are born with heart defects, with the prenatal incidence naturally being even higher. Among all congenital heart defects (CHD), conotruncal anomalies are the most common critical heart defects - after ventricular and atrial septal defects. Conotruncal anomalies are anomalies of the infundibulum (conus arteriosus) and great vessels (truncus arteriosus). These anomalies predominantly affect the right ventricular outflow tract and account for about 25-30 % of all CHD cases. Based on their incidence and clinical relevance, this article describes perimembranous ventricular septal defects (VSD), tetralogy of Fallot (TOF), pulmonary atresia with VSD (PAVSD), transposition of the great arteries (TGA), and the less common double outlet right ventricle (DORV) and truncus arteriosus communis (TAC).Conotruncal anomalies are usually associated with a normal 4-chamber view, so the prenatal detection rate during prenatal care tends to be low. However, because undetected conotruncal anomalies have high rates of postnatal mortality and morbidity, in accordance with internationally recommended policies, the foetal heart should always be examined systematically and segmentally in different sectional planes, including the outflow tract and in combination with the color Doppler, to achieve a higher detection rate. This article provides an overview of prenatal sonographic diagnosis of conotruncal anomalies based on extensive imaging material.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"536-559"},"PeriodicalIF":2.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145024676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01Epub Date: 2025-03-12DOI: 10.1055/a-2525-6117
Yannick Alexander Schreiner, Johannes Lukas Schmidt, Meike Weis, Oliver Nowak, Thomas Kohl, Svetlana Hetjens, Neysan Rafat, Thomas Schaible
To investigate the correlation between different prenatal imaging techniques in congenital diaphragmatic hernia (CDH) and their prognostic value.209 fetuses with CDH were enrolled in this retrospective cohort study. The prenatal ultrasound-based and MRI-based (MRI: magnetic resonance imaging) observed-to-expected lung-to-head ratio (o/e-LHR) and MRI-based relative fetal lung volume (rFLV) were evaluated and compared. Their prediction component with respect to clinical outcome was evaluated. Mean values were compared by two-sample t-tests or the Mann-Whitney U-test. The Chi-square or Fisher's exact test was used in order to compare qualitative parameters. Kappa coefficients, McNemar test, and Bowker's test were used to assess the degree of agreement.The study population included 183 fetuses with left-sided and 26 fetuses with right-sided CDH. Survival did not differ significantly (74.3% vs. 80.8%, p=0.053). For every imaging technique, incidences of extracorporeal membrane oxygenation (ECMO) and chronic lung disease decreased, and the probability of survival increased gradually reaching minima and maxima for o/e-LHR and rFLV above 35%. Outcome improved if rFLV was above 35% - compared to MRI-based measurement of o/e-LHR above 35%.Our data confirm the predictive value of o/e-LHR for CDH - irrespective of the diagnostic modality. MRI evaluation of o/e-LHR was not superior compared to sonography. MRI evaluation of rFLV correlated with morbidity and mortality which can be beneficial for fetuses with an otherwise good prognosis based on higher o/e-LHR as 2D imaging techniques can underestimate the fetuses' risk for pulmonary hypertension and ECMO.
{"title":"Measurements of Lung Size in Ultrasound and Magnetic Resonance Imaging in Congenital Diaphragmatic Hernia - A Comparison of Prenatal Imaging Techniques.","authors":"Yannick Alexander Schreiner, Johannes Lukas Schmidt, Meike Weis, Oliver Nowak, Thomas Kohl, Svetlana Hetjens, Neysan Rafat, Thomas Schaible","doi":"10.1055/a-2525-6117","DOIUrl":"10.1055/a-2525-6117","url":null,"abstract":"<p><p>To investigate the correlation between different prenatal imaging techniques in congenital diaphragmatic hernia (CDH) and their prognostic value.209 fetuses with CDH were enrolled in this retrospective cohort study. The prenatal ultrasound-based and MRI-based (MRI: magnetic resonance imaging) observed-to-expected lung-to-head ratio (o/e-LHR) and MRI-based relative fetal lung volume (rFLV) were evaluated and compared. Their prediction component with respect to clinical outcome was evaluated. Mean values were compared by two-sample t-tests or the Mann-Whitney U-test. The Chi-square or Fisher's exact test was used in order to compare qualitative parameters. Kappa coefficients, McNemar test, and Bowker's test were used to assess the degree of agreement.The study population included 183 fetuses with left-sided and 26 fetuses with right-sided CDH. Survival did not differ significantly (74.3% vs. 80.8%, p=0.053). For every imaging technique, incidences of extracorporeal membrane oxygenation (ECMO) and chronic lung disease decreased, and the probability of survival increased gradually reaching minima and maxima for o/e-LHR and rFLV above 35%. Outcome improved if rFLV was above 35% - compared to MRI-based measurement of o/e-LHR above 35%.Our data confirm the predictive value of o/e-LHR for CDH - irrespective of the diagnostic modality. MRI evaluation of o/e-LHR was not superior compared to sonography. MRI evaluation of rFLV correlated with morbidity and mortality which can be beneficial for fetuses with an otherwise good prognosis based on higher o/e-LHR as 2D imaging techniques can underestimate the fetuses' risk for pulmonary hypertension and ECMO.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"585-593"},"PeriodicalIF":2.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12700711/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143617818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the editor: Safety of contrast-enhanced ultrasound using microbubbles in human pregnancy: A scoping review.","authors":"Juliette Lefebvre, Matthieu Dap, Charline Bertholdt","doi":"10.1055/a-2479-8908","DOIUrl":"10.1055/a-2479-8908","url":null,"abstract":"","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"614-615"},"PeriodicalIF":2.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142822821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01Epub Date: 2026-01-21DOI: 10.1055/a-2782-8515
Malin Reuting, Maren Zapke, Felix Wachter, Roman Raming, Henriette Mandelbaum, Emmanuel Nedoschill, Gregor Siebenlist, Margit Schmid, Joachim Woelfle, Adrian P Regensburger, Jörg Jüngert, Ferdinand Knieling
{"title":"Correction: Effect of head positioning on cerebral blood velocity in the basilar artery in neonates and young infants: A single-center, retrospective analysis.","authors":"Malin Reuting, Maren Zapke, Felix Wachter, Roman Raming, Henriette Mandelbaum, Emmanuel Nedoschill, Gregor Siebenlist, Margit Schmid, Joachim Woelfle, Adrian P Regensburger, Jörg Jüngert, Ferdinand Knieling","doi":"10.1055/a-2782-8515","DOIUrl":"https://doi.org/10.1055/a-2782-8515","url":null,"abstract":"","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":"46 6","pages":"e18"},"PeriodicalIF":2.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146020454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01Epub Date: 2025-02-05DOI: 10.1055/a-2479-8829
Timo Turowski, Martin Fleck, Boris Ehrenstein, Wolfgang Hartung, Florian Günther
Ultra-high-frequency ultrasound (UHF-US) allows visualization of the epidermis, dermis, and subcutis and precise measurement of skin thickness. The aim of this study was to assess the performance and interobserver reliability of UHF-US for measuring skin thickness in patients with long-term systemic glucocorticoid (GC) therapy compared to patients without GC therapy or treated for a shorter period.156 patients with known or suspected inflammatory rheumatic diseases underwent US evaluation for skin thickness by 3 experts in 3 anatomical sites (hand, distal, and proximal forearm). 87 patients were classified as "frequent users" who had received continuous oral GCs for at least one year or at least 3 years with various interruptions. 69 patients without any oral GC therapy in the past or treated for a shorter period were classified as "non-frequent users".UHF-US allowed a precise measurement of skin thickness. Skin thickness at all 3 anatomical sites was significantly decreased in "frequent users" of GCs compared to "non-frequent users" (distal and proximal forearm: p < 0.001; hand: p < 0.05). At all 3 anatomical sites, skin thickness was decreased in patients with clinically assessed parchment-like skin compared to patients without parchment-like skin (distal and proximal forearm: p < 0.001; hand: p < 0.05). Interobserver variability was excellent [hand intraclass correlation coefficient (ICC) = 0.99; proximal forearm ICC = 0.85; distal forearm ICC = 0.84].These data support the idea of UHF-US as an objective and reliable imaging tool for monitoring skin atrophy as adverse effects of GC therapy.
{"title":"Performance of ultra-high-frequency ultrasound in the evaluation of skin atrophy in patients with long-term oral glucocorticoid therapy in a tertiary rheumatology center.","authors":"Timo Turowski, Martin Fleck, Boris Ehrenstein, Wolfgang Hartung, Florian Günther","doi":"10.1055/a-2479-8829","DOIUrl":"10.1055/a-2479-8829","url":null,"abstract":"<p><p>Ultra-high-frequency ultrasound (UHF-US) allows visualization of the epidermis, dermis, and subcutis and precise measurement of skin thickness. The aim of this study was to assess the performance and interobserver reliability of UHF-US for measuring skin thickness in patients with long-term systemic glucocorticoid (GC) therapy compared to patients without GC therapy or treated for a shorter period.156 patients with known or suspected inflammatory rheumatic diseases underwent US evaluation for skin thickness by 3 experts in 3 anatomical sites (hand, distal, and proximal forearm). 87 patients were classified as \"frequent users\" who had received continuous oral GCs for at least one year or at least 3 years with various interruptions. 69 patients without any oral GC therapy in the past or treated for a shorter period were classified as \"non-frequent users\".UHF-US allowed a precise measurement of skin thickness. Skin thickness at all 3 anatomical sites was significantly decreased in \"frequent users\" of GCs compared to \"non-frequent users\" (distal and proximal forearm: p < 0.001; hand: p < 0.05). At all 3 anatomical sites, skin thickness was decreased in patients with clinically assessed parchment-like skin compared to patients without parchment-like skin (distal and proximal forearm: p < 0.001; hand: p < 0.05). Interobserver variability was excellent [hand intraclass correlation coefficient (ICC) = 0.99; proximal forearm ICC = 0.85; distal forearm ICC = 0.84].These data support the idea of UHF-US as an objective and reliable imaging tool for monitoring skin atrophy as adverse effects of GC therapy.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"578-584"},"PeriodicalIF":2.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143256935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01Epub Date: 2025-12-12DOI: 10.1055/a-2702-5692
Valentin Blank, Deike Strobel, Thomas Karlas
{"title":"\"Green Medical Imaging\" - Ultrasound rediscovered as a resource-saving future technology in clinical imaging.","authors":"Valentin Blank, Deike Strobel, Thomas Karlas","doi":"10.1055/a-2702-5692","DOIUrl":"https://doi.org/10.1055/a-2702-5692","url":null,"abstract":"","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":"46 6","pages":"530-535"},"PeriodicalIF":2.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145745437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01Epub Date: 2025-08-07DOI: 10.1055/a-2592-1431
Nina Dominik, Larissa Nixdorf, Michael Schwarz, Benedikt Silvester Hofer, Lukas Hartl, Lorenz Balcar, Georg Semmler, Benedikt Simbrunner, Laurenz Fritz, Laurenz Hauptmann, Mathias Jachs, Julia Jedamzik, Behrang Mozayani, Lisa Gensthaler, Daniel Moritz Felsenreich, Mattias Mandorfer, Felix Langer, Michael Trauner, Thomas Reiberger, Gerhard Prager, David Jm Bauer
Metabolic dysfunction-associated steatotic liver disease (MASLD) can progress to fibrosis and cirrhosis. Fibrosis and steatosis assessment with vibration-controlled transient elastography (VCTE) and controlled attenuation parameter (CAP) requires a dedicated device and time to obtain ≥10 reliable measurements. Auto pSWE allows for the simultaneous collection of 15 ARFI-based liver stiffness measurements (LSM) and UDFF-based steatosis assessment in a single acquisition.This prospective study included patients undergoing liver biopsy, primarily during bariatric surgery, between 11/2021-12/2023. Paired LSM by Auto pSWE/VCTE and steatosis assessments by UDFF/CAP were performed within a median of 1 day before or after biopsy.134 patients (65% women, mean age: 42.6±13.3 years) with a high prevalence of obesity (mean BMI: 42.7±10.4; MASLD etiology: 88%) were included. Liver biopsy showed significant fibrosis (≥F2) in 27% of patients and moderate steatosis (≥S2) in 51%. A single 1×15 Auto pSWE acquisition and one UDFF measurement were as accurate as the median of 5 measurements. Auto pSWE (AUC: ≥F2=0.58, ≥F3=0.96, F4=0.97) and VCTE (AUC: ≥F2=0.60, ≥F3=0.92, F4=0.93) demonstrated high accuracy for advanced fibrosis stages. UDFF (AUC: ≥S1=0.79, ≥S2=0.78, S3=0.67) and CAP showed similar diagnostic accuracy.Auto pSWE and UDFF provide accurate, noninvasive tests for advanced liver fibrosis and steatosis in MASLD, even in severely obese patients. Notably, Auto pSWE captures 15 LSM with UDFF in a single acquisition, saving time and eliminating the need for a dedicated device.
{"title":"UDFF and Auto pSWE accurately assess liver steatosis and fibrosis risk in obese patients with MASLD.","authors":"Nina Dominik, Larissa Nixdorf, Michael Schwarz, Benedikt Silvester Hofer, Lukas Hartl, Lorenz Balcar, Georg Semmler, Benedikt Simbrunner, Laurenz Fritz, Laurenz Hauptmann, Mathias Jachs, Julia Jedamzik, Behrang Mozayani, Lisa Gensthaler, Daniel Moritz Felsenreich, Mattias Mandorfer, Felix Langer, Michael Trauner, Thomas Reiberger, Gerhard Prager, David Jm Bauer","doi":"10.1055/a-2592-1431","DOIUrl":"10.1055/a-2592-1431","url":null,"abstract":"<p><p>Metabolic dysfunction-associated steatotic liver disease (MASLD) can progress to fibrosis and cirrhosis. Fibrosis and steatosis assessment with vibration-controlled transient elastography (VCTE) and controlled attenuation parameter (CAP) requires a dedicated device and time to obtain ≥10 reliable measurements. Auto pSWE allows for the simultaneous collection of 15 ARFI-based liver stiffness measurements (LSM) and UDFF-based steatosis assessment in a single acquisition.This prospective study included patients undergoing liver biopsy, primarily during bariatric surgery, between 11/2021-12/2023. Paired LSM by Auto pSWE/VCTE and steatosis assessments by UDFF/CAP were performed within a median of 1 day before or after biopsy.134 patients (65% women, mean age: 42.6±13.3 years) with a high prevalence of obesity (mean BMI: 42.7±10.4; MASLD etiology: 88%) were included. Liver biopsy showed significant fibrosis (≥F2) in 27% of patients and moderate steatosis (≥S2) in 51%. A single 1×15 Auto pSWE acquisition and one UDFF measurement were as accurate as the median of 5 measurements. Auto pSWE (AUC: ≥F2=0.58, ≥F3=0.96, F4=0.97) and VCTE (AUC: ≥F2=0.60, ≥F3=0.92, F4=0.93) demonstrated high accuracy for advanced fibrosis stages. UDFF (AUC: ≥S1=0.79, ≥S2=0.78, S3=0.67) and CAP showed similar diagnostic accuracy.Auto pSWE and UDFF provide accurate, noninvasive tests for advanced liver fibrosis and steatosis in MASLD, even in severely obese patients. Notably, Auto pSWE captures 15 LSM with UDFF in a single acquisition, saving time and eliminating the need for a dedicated device.</p>","PeriodicalId":49400,"journal":{"name":"Ultraschall in Der Medizin","volume":" ","pages":"603-613"},"PeriodicalIF":2.9,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12700709/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144800709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}