Neurobrucellosis can present as raised intracranial pressure (headache, diplopia, and papilledema) without fever or meningeal signs. Steroids might be helpful in the management.
Neurobrucellosis can present as raised intracranial pressure (headache, diplopia, and papilledema) without fever or meningeal signs. Steroids might be helpful in the management.
Meigs syndrome is characterised by the triad of ovarian fibroma associated with ascites and pleural effusion, the latter of which resolves after removal of the fibroma. This uncommon but important clinical entity mimics malignancy in postmenopausal females. We present two such cases.
Chikungunya fever is an arboviral disease and remains a major public health concern in India ever since its first emergence in 1963 in Kolkata. Delhi has witnessed several outbreaks over the years. This retrospective study was performed to examine the epidemiological dynamics on all clinically suspected Chikungunya cases tested by ELISA for anti-CHIK virus IgM antibodies from 2010 to 2020 at a tertiary care hospital in Delhi. Archived data of suspected patients screened for CHIKV IgM by ELISA were retrieved for the period 2010-2020. Epidemiological data was used in the study. GIS mapping was done for the positive cases. Among the 445 samples tested, 57.3% were positive with the greatest number of cases (76.5%) in 2016 and significantly higher number of cases in monsoon & post-monsoon periods (p < 0.005). Seropositivity was highest in patients aged 45-54 years (69.6%); however, the disease did not show predilection for a specific gender. GIS mapping showed the burden of Chikungunya infection was concentrated in a 5-10 km radius from the study site with significant presence of cross-border cases. Our study indicates a geographically concentrated burden of Chikungunya in East and South East Delhi with ebbs and flow over time in the past decade. In view of non-availability of any licensed vaccine for this disease, surveillance of active cases, vector management and mapping of disease may help in prevention strategies.
Melioidosis, an infection caused by the Gram-negative bacterium Burkholderia pseudomallei, has earned the nickname 'the great mimicker' owing to its tendency to resemble common infections, often leading to a delayed diagnosis and high mortality. We report three cases where it mimicked scrub typhus, tubercular arthritis, and Klebsiella pneumoniae infection. The diagnosis of melioidosis was achieved by extensive workup; our case series sends the lesson that none should stop and settle for less, but continuously search for the actual pathogen where no adequate response to treatment is perceived.
Our study looks at malaria data from 2016 to 2021 in Meta in Colombia, where most cases were found in Puerto Gaitán, Villavicencio and Mapiripán. A significant relationship was found between age category and acquiring malaria. Although not a part of the malaria endemic zone, Meta has municipalities located near rivers, where contact with the vector is enhanced. No eradication programme will succeed without the cooperation of its inhabitants.
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