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Diaphragmatic pacing for respiratory failure in children 膈肌起搏治疗儿童呼吸衰竭
IF 1.7 3区 医学 Q3 PEDIATRICS Pub Date : 2024-01-09 DOI: 10.1016/j.sempedsurg.2024.151386
Daniel J. Robertson , Paul M. Jeziorczak , Charles J. Aprahamian

Diaphragm pacing is a ventilation strategy in respiratory failure. Most of the literature on pacing involves adults with common indications being spinal cord injury and amyotrophic lateral sclerosis (ALS). Previous reports in pediatric patients consist of case reports or small series; most describe direct phrenic nerve stimulation for central hypoventilation syndrome. This differs from adult reports that focus most commonly on spinal cord injuries and the rehabilitative nature of diaphragm pacing. This review describes the current state of diaphragm pacing in pediatric patients. Indications, current available technologies, surgical techniques, advantages, and pitfalls/problems are discussed.

膈肌起搏是呼吸衰竭的一种通气策略。有关起搏的文献大多涉及成人,常见的适应症是脊髓损伤和肌萎缩性脊髓侧索硬化症(ALS)。以前关于儿科患者的报道主要是病例报告或小型系列报道;大多数都是描述直接膈神经刺激治疗中枢通气不足综合征。这与成人的报道不同,成人的报道通常侧重于脊髓损伤和膈肌起搏的康复性质。本综述介绍了膈肌起搏在儿科患者中的应用现状。其中讨论了适应症、当前可用的技术、手术技术、优势和隐患/问题。
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引用次数: 0
Non-surgical approaches to the management of chest wall deformities 治疗胸壁畸形的非手术方法
IF 1.7 3区 医学 Q3 PEDIATRICS Pub Date : 2024-01-08 DOI: 10.1016/j.sempedsurg.2024.151388
Jacky Z Kwong, Brian CH Gulack

Chest wall deformities in children encompass a broad spectrum of disorders but pectus excavatum and carinatum are by far the most common. Treatment varies substantially by center, and depends on patient symptoms, severity of disease, and surgeon preference.

Historically, surgical approaches were the mainstay of treatment for these disease processes but new advances in non-surgical approaches have demonstrated reasonable results in select patients. These non-surgical approaches include vacuum bell therapy, autologous fat grafting and hyaluronic acid injections for pectus excavatum, and orthotic brace therapy for pectus carinatum. There is debate with regards to optimal patient selection for these non-surgical approaches, as well as other barriers including reimbursement issues.

This paper will review the current non-surgical approaches to chest wall deformities available, including optimal patient selection, treatment protocols, indications, contraindications, and outcomes.

儿童胸壁畸形包括多种疾病,但迄今为止最常见的是挖空胸和贲门失弛缓症。不同中心的治疗方法大相径庭,取决于患者的症状、疾病的严重程度和外科医生的偏好。历史上,手术方法是治疗这些疾病过程的主要方法,但非手术方法的新进展已在部分患者身上取得了合理的效果。这些非手术方法包括真空钟疗法、自体脂肪移植和透明质酸注射治疗挖掘性鸡胸,以及矫正支架疗法治疗鸡胸。本文将回顾目前治疗胸壁畸形的非手术方法,包括最佳患者选择、治疗方案、适应症、禁忌症和疗效。
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引用次数: 0
Artificial intelligence in pediatric surgery 人工智能在小儿外科中的应用
IF 1.7 3区 医学 Q3 PEDIATRICS Pub Date : 2024-01-06 DOI: 10.1016/j.sempedsurg.2024.151390
Anthony Y. Tsai , Stewart R. Carter , Alicia C. Greene

Artificial intelligence (AI) is rapidly changing the landscape of medicine and is already being utilized in conjunction with medical diagnostics and imaging analysis. We hereby explore AI applications in surgery and examine its relevance to pediatric surgery, covering its evolution, current state, and promising future. The various fields of AI are explored including machine learning and applications to predictive analytics and decision support in surgery, computer vision and image analysis in preoperative planning, image segmentation, surgical navigation, and finally, natural language processing assist in expediting clinical documentation, identification of clinical indications, quality improvement, outcome research, and other types of automated data extraction. The purpose of this review is to familiarize the pediatric surgical community with the rise of AI and highlight the ongoing advancements and challenges in its adoption, including data privacy, regulatory considerations, and the imperative for interdisciplinary collaboration. We hope this review serves as a comprehensive guide to AI's transformative influence on surgery, demonstrating its potential to enhance pediatric surgical patient outcomes, improve precision, and usher in a new era of surgical excellence.

人工智能(AI)正在迅速改变医学的面貌,并已被用于医学诊断和成像分析。在此,我们将探讨人工智能在外科手术中的应用,并研究其与小儿外科手术的相关性,包括其演变、现状和充满希望的未来。我们探讨了人工智能的各个领域,包括机器学习及其在手术预测分析和决策支持中的应用,计算机视觉和图像分析在术前规划、图像分割、手术导航中的应用,以及自然语言处理在加快临床文件记录、临床适应症识别、质量改进、结果研究和其他类型的自动数据提取中的应用。本综述旨在让儿科手术界了解人工智能的崛起,并强调在采用人工智能过程中不断取得的进步和面临的挑战,包括数据隐私、监管方面的考虑以及跨学科合作的必要性。我们希望这篇综述能成为一份全面的指南,让人们了解人工智能对外科手术的变革性影响,展示人工智能在提高儿科手术患者预后、提高精准度以及开创卓越外科新时代方面的潜力。
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引用次数: 0
Framework for pediatric robotic surgery program development 小儿机器人手术项目开发框架
IF 1.7 3区 医学 Q3 PEDIATRICS Pub Date : 2024-01-06 DOI: 10.1016/j.sempedsurg.2024.151389
Chirag Ram , J. Benjamin Pitt , Marshall W. Wallace , Seth D. Goldstein , Irving J. Zamora

Pediatric robotic surgery has seen increasing implementation for its many benefits over the past two decades. As more pediatric surgeons gain exposure to robotic surgery, the interest in utilizing this technology is growing. However, there are no guidelines or existing framework for developing pediatric general surgery robotic programs. Programmatic development can be challenging, requiring institutional support, a minimum 12-month multistep process in partnership with the robot manufacturer, and organization of a local dedicated team. A cornerstone to all program building is collaboration and communication with key stakeholders who are committed to establishing a robotic surgery program. In this manuscript, we detail numerous best practices for implementation, followed by three variations of programmatic development, each drawing lessons from one of three practice settings: (i) A children's hospital in a large medical center associated with an adult hospital, (ii) a free-standing children's hospital, and (iii) a community-based practice. We aim for this article to provide a framework that can serve as a guide for those beginning this process, consolidating the key resources and strategies used to develop a robust pediatric robotic surgery program.

在过去二十年里,小儿机器人手术因其诸多优点而得到越来越多的应用。随着越来越多的小儿外科医生开始接触机器人手术,人们对这项技术的兴趣也越来越浓厚。然而,目前还没有制定小儿普外科机器人手术计划的指南或现有框架。计划的制定可能极具挑战性,需要机构的支持、与机器人制造商合作的至少12个月的多步骤流程,以及当地专门团队的组织。所有项目建设的基石是与致力于建立机器人手术项目的主要利益相关者进行合作和沟通。在本手稿中,我们详细介绍了许多最佳实施方法,随后介绍了三种不同的项目发展模式,每种模式都从以下三种实践环境中汲取了经验:(i) 与成人医院有关联的大型医疗中心内的儿童医院;(ii) 独立的儿童医院;(iii) 社区实践。本文旨在提供一个框架,为开始这一过程的人提供指导,整合用于发展强大的儿科机器人手术项目的关键资源和策略。
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引用次数: 0
Indocyanine green (ICG) fluorescence-enhanced applications in pediatric surgery 吲哚菁绿(ICG)荧光增强技术在小儿外科手术中的应用
IF 1.7 3区 医学 Q3 PEDIATRICS Pub Date : 2024-01-05 DOI: 10.1016/j.sempedsurg.2024.151384
John Sincavage , Brian C. Gulack , Irving J. Zamora

The breadth of pediatric surgical practice and variety of anatomic anomalies that characterize surgical disease in children and neonates require a unique level of operative mastery and versatility. Intraoperative navigation of small, complex, and often abnormal anatomy presents a particular challenge for pediatric surgeons. Clinical experience with fluorescent tissue dye, specifically indocyanine green (ICG), is quickly gaining widespread incorporation into adult surgical practice as a safe, non-toxic means of accurately visualizing tissue perfusion, lymphatic flow, and biliary anatomy to enhance operative speed, safety, and patient outcomes. Experience in pediatric surgery, however, remains limited. ICG-fluorescence guided surgery is poised to address the challenges of pediatric and neonatal operations for a growing breadth of surgical pathology. Fluorescent angiography has permitted intraoperative visualization of colorectal flap perfusion for complex pelvic reconstruction and anastomotic perfusion after esophageal atresia repair, while its hepatic absorption and biliary excretion has made it an excellent agent for delineating the dissection plane in the Kasai portoenterostomy and identifying both primary and metastatic hepatoblastoma lesions. Subcutaneous and intra-lymphatic ICG injection can identify iatrogenic chylous leaks and improved yields in sentinel lymph node biopsies. ICG-guided surgery holds promise for more widespread use in pediatric surgical conditions, and continued evaluation of efficacy will be necessary to better inform clinical practice and identify where to focus and develop this technical resource.

小儿外科手术范围广泛,儿童和新生儿外科疾病的解剖畸形种类繁多,这就要求小儿外科医生具有独特的手术技巧和多才多艺。对于小而复杂且经常异常的解剖结构,术中导航对小儿外科医生来说是一项特殊的挑战。荧光组织染料(特别是吲哚菁绿(ICG))作为一种安全、无毒的方法,可准确显示组织灌注、淋巴流和胆道解剖结构,从而提高手术速度、安全性和患者疗效,因此很快被广泛应用于成人外科手术中。然而,儿科手术的经验仍然有限。ICG-荧光引导手术可以应对小儿和新生儿手术中日益广泛的外科病理挑战。荧光血管造影术允许在术中观察复杂骨盆重建的结直肠皮瓣灌注情况和食道闭锁修复后的吻合口灌注情况,而其肝脏吸收和胆汁排泄功能使其成为在葛西肠管造口术中划定解剖平面以及识别原发性和转移性肝母细胞瘤病灶的绝佳药物。皮下和淋巴管内注射 ICG 可以识别先天性乳糜泻,并提高前哨淋巴结活检的产量。ICG 引导手术有望在儿科手术中得到更广泛的应用,为了更好地指导临床实践,确定这一技术资源的重点和发展方向,有必要对其疗效进行持续评估。
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引用次数: 0
Intercostal spinal nerve cryoablation for analgesia following pectus excavatum repair 肋间脊神经冷冻消融术用于胸肌修复术后镇痛
IF 1.7 3区 医学 Q3 PEDIATRICS Pub Date : 2024-01-04 DOI: 10.1016/j.sempedsurg.2024.151382
Mallory N. Perez , Anthony Ferrantella , Kevin N. Johnson , Seth D. Goldstein

Pectus excavatum is a common chest wall deformity, most often treated during adolescence, that presents a significant postoperative pain control challenge for pediatric surgeons following surgical correction. The purpose of this article is to review the technique and outcomes of intercostal spinal nerve cryoablation for postoperative analgesia following surgical correction of pectus excavatum. Contemporary and historic literature were reviewed. Findings are summarized to provide a concise synopsis of the benefits of intercostal spinal nerve cryoablation relative to alternative analgesic modalities, as well as advocate for more widespread inclusion of this technique into multimodal pain regimens.

鸡胸是一种常见的胸壁畸形,多在青少年时期接受治疗,手术矫正后的术后疼痛控制给儿科医生带来了巨大挑战。本文旨在回顾肋间脊神经低温消融术用于手术矫正胸肌后镇痛的技术和效果。文章回顾了当代和历史文献。文章对研究结果进行了总结,简要概括了肋间脊神经低温消融术相对于其他镇痛方式的优势,并提倡在多模式镇痛方案中更广泛地采用这种技术。
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引用次数: 0
Applications for ultrasound in pediatric surgery 超声波在小儿外科手术中的应用
IF 1.7 3区 医学 Q3 PEDIATRICS Pub Date : 2024-01-04 DOI: 10.1016/j.sempedsurg.2024.151383
Kevin N. Johnson , Jonathan Vacek , Stewart Carter

Ultrasound (US) use within pediatric surgery is expanding rapidly. While US guidance for central line placement has been common practice for many years now, advances in the quality of images, portability of US machines, and a lack of radiation associated with imaging has led to broader application in many other aspects of surgery, ranging from diagnostics to performing operations under the direction of point-of-care ultrasound (POCUS). The relatively short learning curve for providers along with excellent image quality in children due to their small size provides an easy, effective imaging modality with diverse applications. Discussed here is a broad overview of the spectrum of US use within current pediatric surgical practices.

超声波(US)在儿科手术中的应用正在迅速扩大。多年来,超声引导中心静脉置管已成为普遍做法,而图像质量、超声设备便携性和成像无辐射等方面的进步,使其在外科手术的许多其他方面得到了更广泛的应用,从诊断到在床旁超声(POCUS)的指导下进行手术。由于儿童体型较小,因此学习曲线相对较短,而且图像质量极佳,是一种应用广泛、简单有效的成像方式。这里讨论的是当前儿科手术实践中超声应用的广泛概述。
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引用次数: 0
3D printing in pediatric surgery 儿科手术中的 3D 打印
IF 1.7 3区 医学 Q3 PEDIATRICS Pub Date : 2024-01-04 DOI: 10.1016/j.sempedsurg.2024.151385
Anthony Y. Tsai, Alicia C. Greene

Pediatric surgery presents a unique challenge, requiring a specialized approach due to the intricacies of compact anatomy and the presence of distinct congenital features in young patients. Surgeons are tasked with making decisions that not only address immediate concerns but also consider the evolving needs of children as they grow. The advent of three-dimensional (3D) printing has emerged as a valuable tool to facilitate a personalized medical approach. This paper starts by outlining the basics of 3D modeling and printing. We then delve into the transformative role of 3D printing in pediatric surgery, elucidating its applications, benefits, and challenges. The paper concludes by envisioning the future prospects of 3D printing, foreseeing advancements in personalized treatment approaches, improved patient outcomes, and the continued evolution of this technology as an indispensable asset in the pediatric surgical arena.

小儿外科是一项独特的挑战,由于小儿解剖结构复杂,且存在明显的先天特征,因此需要采用专门的方法。外科医生在做决定时不仅要解决当下的问题,还要考虑到儿童成长过程中不断变化的需求。三维(3D)打印技术的出现成为促进个性化医疗方法的重要工具。本文首先概述了三维建模和打印的基础知识。然后,我们深入探讨了三维打印在儿科手术中的变革性作用,阐明了它的应用、优势和挑战。最后,本文展望了 3D 打印技术的未来前景,预见了个性化治疗方法的进步、患者疗效的改善以及该技术作为小儿外科领域不可或缺的资产的持续发展。
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引用次数: 0
Use of magnets in pediatric surgery 在小儿外科手术中使用磁铁
IF 1.7 3区 医学 Q3 PEDIATRICS Pub Date : 2024-01-04 DOI: 10.1016/j.sempedsurg.2024.151381
Norah E. Liang , Saunders Lin , Bethany J. Slater , Matias Bruzoni

Since the 1970s, magnets have been progressively harnessed for use in minimally invasive treatment of pediatric surgical disease. In particular, multiple magnetic devices have been developed for treating esophageal atresia, pectus excavatum and scoliosis. These devices, which can be placed via small incisions or under endoscopic or fluoroscopic guidance, provide the added benefit of sparing patients multiple large, invasive procedures, and allowing for gradual correction of congenital anomalies over days to months, depending on the disease. In the following text, we detail the current landscape of magnetic devices used by pediatric surgeons, illustrate their use through clinical cases, and review the available body of literature with respect their outcomes and complications.

自 20 世纪 70 年代以来,磁铁逐渐被用于小儿外科疾病的微创治疗。特别是,目前已开发出多种磁性装置,用于治疗食道闭锁、鸡胸和脊柱侧弯。这些装置可通过小切口或在内窥镜或透视镜引导下放置,其额外的好处是患者无需进行多次大型侵入性手术,并可根据疾病情况在数天至数月内逐渐矫正先天性畸形。在下面的文章中,我们将详细介绍小儿外科医生目前使用的磁性设备,通过临床病例说明其用途,并回顾有关其结果和并发症的现有文献。
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引用次数: 0
Children's Anaesthesia and perioperative care challenges, and innovations 儿童麻醉与围手术期护理的挑战与创新
IF 1.7 3区 医学 Q3 PEDIATRICS Pub Date : 2023-12-01 DOI: 10.1016/j.sempedsurg.2023.151355
Z. Gathuya , M.T. Nabukenya , O. Aaron , R. Gray , F.M. Evans
<div><p>The 2015 Sustainable Development Goals emphasise good health to all with reduced inequalities, and surgical and anaesthesia care is essential to achieve these. <span>https://sdgs.un.org/goals</span><svg><path></path></svg><span>. However, it has been estimated that 1.7 billion children do not have access to safe anaesthesia and surgery when needed and this disproportionately affects children in low- and middle-income countries (1). It is alarming that 1 in 10 individuals in LMICs do not have access to safe surgical care. Both safe surgery and anaesthesia are essential for ensuring that individuals receive proper medical attention. Economically viable public health initiatives that can avert many disability-adjusted years are needed. (2–4)</span></p><p><span>Morbidity and mortality from surgical disease and anaesthesia care remain high in low-income countries, unlike in high-income countries. The incidence of severe anaesthesia-related critical events and perioperative cardiac arrest is between three and ten times more in LMICs than in HICs (5–7) A baseline POMR that is 100 times higher in LMICs compared to HICs is reported. (8) This perioperative morbidity and mortality gap is more evident in neonates and younger age groups, especially in children with congenital abnormalities. The challenges facing providers of anaesthesia and perioperative care<span> are multifactorial and include but are not limited to the inadequate workforce, inadequate and inappropriate infrastructure, lack of adequate and appropriately sized equipment, including monitors, and safe monitoring capacity, supply chain challenges for medicines and reusable consumables, unreliable supply of oxygen and blood products, lack of data and research for policy formulation, inadequate resource allocation from governments and lack of safety culture among other things. In paediatrics, this is further multiplied by the variability in the sizes of the patients, from neonates to older children (9).</span></span></p><ul><li><span>1.</span><span><p>Improved perioperative care must include anaesthesia and nursing to improve perioperative outcomes for children.</p></span></li><li><span>2.</span><span><p>Perioperative care for children in LMICs is predominantly by non-physician anaesthesia providers or non-specialty-trained anaesthesiologists.</p></span></li><li><span>3.</span><span><p>There is a need to train physician anaesthesia leaders to direct and oversee the care of children undergoing anaesthesia</p></span></li><li><span>4.</span><span><p>Infrastructure and equipment for the safe provision of paediatric anaesthesia/perioperative care are usually wanting/often times inadequate and inappropriate.</p></span></li><li><span>5.</span><span><p>The GICS OReCS document provides a valuable guide for the bare minimum requirements for the provision of safe paediatric anaesthetic and surgical care services, starting at the district hospital.</p></span></li><li><span>6.</span><span><p>Equipment
2015年可持续发展目标强调人人享有良好健康,减少不平等现象,手术和麻醉护理对实现这些目标至关重要。https://sdgs.un.org/goals。然而,据估计,有17亿儿童在需要时无法获得安全的麻醉和手术,这对低收入和中等收入国家的儿童影响尤为严重(1)。令人震惊的是,中低收入国家中十分之一的人无法获得安全的手术护理。安全手术和麻醉对于确保个人得到适当的医疗照顾至关重要。需要采取经济上可行的公共卫生举措,避免许多残疾调整年。(2-4)与高收入国家不同,低收入国家外科疾病和麻醉护理的发病率和死亡率仍然很高。据报道,中低收入国家的严重麻醉相关危急事件和围手术期心脏骤停的发生率是高收入国家的3至10倍(5-7)。中低收入国家的基线POMR比高收入国家高100倍。(8)围手术期发病率和死亡率的差距在新生儿和年龄更小的年龄组中更为明显,特别是在有先天性异常的儿童中。麻醉和围手术期护理提供者面临的挑战是多因素的,包括但不限于劳动力不足、基础设施不足和不适当、缺乏足够和适当大小的设备(包括监测器)和安全监测能力、药品和可重复使用消耗品的供应链挑战、氧气和血液制品供应不可靠、缺乏用于政策制定的数据和研究。政府资源分配不足,缺乏安全文化等等。在儿科,从新生儿到年龄较大的儿童,患者的大小差异进一步增加了这一点(9)。改善围手术期护理必须包括麻醉和护理,以改善儿童围手术期预后。低收入和中等收入国家儿童围手术期护理主要由非内科麻醉师或非专业训练麻醉师负责。有必要培训麻醉医师领导,指导和监督接受麻醉的儿童的护理。安全提供儿科麻醉/围手术期护理的基础设施和设备通常缺乏/经常不足和不适当。GICS OReCS文件为从地区医院开始提供安全的儿科麻醉和外科护理服务的最低要求提供了宝贵的指南。设备捐赠应认真负责,并与当地领导协商。考虑因素将包括维护的生物医学支持、备件的可用性和电气兼容性等。针对具体情况的创新已被证明在低收入国家有效,包括针对所有提供者的儿科麻醉课程和使用低技术的基于模拟的培训。任何旨在改善儿童麻醉和手术护理的有价值的项目最终都需要适应国家医疗保健系统。
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引用次数: 0
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Seminars in Pediatric Surgery
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