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Research and Policy. 研究与政策。
IF 2.2 4区 医学 Q1 NURSING Pub Date : 2024-05-01 DOI: 10.1097/NNR.0000000000000720
Rita H Pickler
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引用次数: 0
Overdosing in a Motor Vehicle: Examination of Human, Geographic, and Environmental Factors. 在机动车内服药过量:对人为、地理和环境因素的研究。
IF 2.2 4区 医学 Q1 NURSING Pub Date : 2024-05-01 Epub Date: 2024-02-06 DOI: 10.1097/NNR.0000000000000716
Dahianna S Lopez, Jason Parent, Thomas Stegnicki, Zachariah Kenyon, Kimberly Arcoleo, Liam C Malloy, Michael J Mello

Background: Fentanyl, a type of opioid, in impaired driving cases increased across cities in the United States.

Objectives: No empirical studies have examined motor vehicle overdoses with fentanyl use. We investigated the magnitude of the motor vehicle overdose problem in Providence, RI, and the environmental, socioeconomic, and geographic conditions associated with motor vehicle overdose occurrence.

Methods: This was a retrospective observational study of emergency medical services data on all suspected opioid overdoses between January 1, 2017, and October 31, 2020. The data contain forced-choice fields, such as age and biological sex, and an open-ended narrative in which the paramedic documented clinical and situational information. The overdoses were geocoded, allowing for the extraction of sociodemographic data from the U.S. Census Bureau's American Community Survey. Seven other data sources were included in a logistic regression to understand key risk factors and spatial patterns of motor vehicle overdoses.

Results: Of the 1,357 opioid overdose cases in this analysis, 15.2% were defined as motor vehicle overdoses. In adjusted models, we found a 61% increase in the odds of a motor vehicle overdose involvement for men versus women, a 16.8% decrease in the odds of a motor vehicle overdose for a one-unit increase in distance to the nearest gas station, and a 10.7% decrease in the odds of a motor vehicle overdose for a one-unit increase in distance to a buprenorphine clinic.

Conclusion: There is a need to understand the interaction between drug use in vehicles to design interventions for decreasing driving after illicit drug use.

背景:芬太尼是一种阿片类药物:芬太尼是阿片类药物的一种,在美国各城市的受损驾驶案例中有所增加:没有任何实证研究对使用芬太尼的机动车用药过量进行过调查。我们调查了罗得岛州普罗维登斯市机动车用药过量问题的严重程度,以及与机动车用药过量发生相关的环境、社会经济和地理条件:这是一项回顾性观察研究,研究对象是 2017 年 1 月 1 日至 2020 年 10 月 31 日期间所有疑似阿片类药物过量的紧急医疗服务数据。数据包含强制选择字段(如年龄和生理性别)和开放式叙述,护理人员在叙述中记录了临床和情景信息。对过量用药进行了地理编码,以便从美国人口普查局的美国社区调查中提取社会人口数据。逻辑回归中还包含了其他七个数据源,以了解机动车辆用药过量的主要风险因素和空间模式:在本次分析的 1,357 例阿片类药物过量病例中,15.2% 被定义为机动车辆过量。在调整后的模型中,我们发现男性与女性发生机动车用药过量的几率增加了 61%,与最近加油站的距离每增加一个单位,发生机动车用药过量的几率降低 16.8%,与丁丙诺啡诊所的距离每增加一个单位,发生机动车用药过量的几率降低 10.7%:结论:有必要了解车辆中药物使用之间的相互作用,以便设计干预措施,减少非法药物使用后的驾驶行为。
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引用次数: 0
Implementing a Clinical Decision Support Tool to Improve Physical Activity. 实施临床决策支持工具,改善体育锻炼。
IF 2.2 4区 医学 Q1 NURSING Pub Date : 2024-05-01 Epub Date: 2024-01-11 DOI: 10.1097/NNR.0000000000000714
Margaret M McCarthy, Adam Szerencsy, Leslie Taza-Rocano, Stephanie Hopkins, Devin Mann, Gail D'Eramo Melkus, Allison Vorderstrasse, Stuart D Katz

Background: Currently, only about half of U.S. adults achieve current physical activity guidelines. Routine physical activity is not regularly assessed, nor are patients routinely counseled by their healthcare provider on achieving recommended levels. The three-question physical activity vital sign (PAVS) was developed to assess physical activity duration and intensity and identify adults not meeting physical activity guidelines. Clinical decision support provided via a best practice advisory in an electronic health record (EHR) system can be triggered as a prompt, reminding healthcare providers to implement the best practice intervention when appropriate. Remote patient monitoring of physical activity can provide objective data in the EHR.

Objectives: This study aimed to evaluate the feasibility and clinical utility of embedding the PAVS and a triggered best practice advisor into the EHR in an ambulatory preventive cardiology practice setting to alert providers to patients reporting low physical activity and prompt healthcare providers to counsel these patients as needed.

Methods: Three components based in the EHR were integrated for the purpose of this study: Patients completed the PAVS through their electronic patient portal prior to an office visit, a best practice advisory was created to prompt providers to counsel patients who reported low levels of physical activity, and remote patient monitoring via Fitbit synced to the EHR provided objective physical activity data. The intervention was pilot-tested in the Epic EHR for 1 year (July 1, 2021 to June 30, 2022). Qualitative feedback on the intervention from both providers and patients was obtained at the completion of the study.

Results: Monthly assessments of the use of the PAVS and best practice advisory and remote patient monitoring were completed. Patients' completion of the PAVS varied from 35% to 48% per month. The best practice advisory was signed by providers between 2% and 65% and was acknowledged by 2%-22% per month. The majority (58%) of patients were able to sync a Fitbit device to their EHR for remote monitoring.

Discussion: Although uptake of each component needs improvement, this pilot demonstrated the feasibility of incorporating a physical activity promotion intervention into the EHR. Qualitative feedback provided guidance for future implementation.

背景:目前,只有大约一半的美国成年人达到了现行的体育锻炼指导标准。常规体育锻炼并没有得到定期评估,患者也没有得到医疗服务提供者关于达到建议水平的常规指导。体力活动生命体征(PAVS)由三个问题组成,用于评估体力活动的持续时间和强度,并识别未达到体力活动指南要求的成年人。通过电子健康记录(EHR)系统中的最佳实践建议提供的临床决策支持可以触发提示,提醒医疗服务提供者在适当的时候实施最佳实践干预。远程监测患者的体力活动可在电子病历中提供客观数据:本研究旨在评估在门诊预防性心脏病诊疗环境中将患者体力活动监测系统和触发式最佳实践顾问嵌入电子病历的可行性和临床实用性,以提醒医疗服务提供者注意报告体力活动不足的患者,并提示医疗服务提供者根据需要为这些患者提供咨询服务:本研究整合了电子病历中的三个组件:患者在就诊前通过电子患者门户完成 PAVS;创建最佳实践建议,以提示医疗服务提供者为报告体力活动水平低的患者提供咨询;通过与电子病历同步的 Fitbit 进行远程患者监测,提供客观的体力活动数据。该干预措施在 Epic EHR 中进行了为期一年(2021 年 7 月 1 日至 2022 年 6 月 30 日)的试点测试。研究结束后,从医疗服务提供者和患者处获得了对干预措施的定性反馈:结果:完成了对 PAVS 使用情况、最佳实践咨询和远程患者监测的月度评估。患者每月完成 PAVS 的比例从 35% 到 48% 不等。每月有 2% 至 65% 的医疗服务提供者签署了最佳实践建议,有 2% 至 22% 的医疗服务提供者确认了最佳实践建议。大多数患者(58%)都能将 Fitbit 设备同步到电子病历中进行远程监测:讨论:尽管各组成部分的使用率有待提高,但该试点项目证明了在电子病历中纳入促进锻炼干预措施的可行性。定性反馈为今后的实施提供了指导。
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引用次数: 0
Nutritional Status, Dietary Intake, Quality of Life, and Dysphagia in Women With Fibromyalgia. 纤维肌痛女性患者的营养状况、饮食摄入量、生活质量和吞咽困难。
IF 2.2 4区 医学 Q1 NURSING Pub Date : 2024-05-01 Epub Date: 2024-02-06 DOI: 10.1097/NNR.0000000000000717
María Correa-Rodríguez, María Del Carmen Villaverde-Rodríguez, Antonio Casas-Barragán, Rosa María Tapia-Haro, María Encarnación Aguilar-Ferrándiz

Background: Fibromyalgia syndrome (FMS) is an idiopathic chronic disease characterized by widespread musculoskeletal pain, hyperalgesia, and allodynia that has been recently associated with risk of dysphagia.

Objective: We aimed to analyze the association between nutritional status, micro- and macronutrient intake, and quality of life (QoL) in a cohort of women with FMS and risk of dysphagia compared to women with FMS without risk of dysphagia.

Methods: A cross-sectional study was conducted in 46 women with FMS. Risk of dysphagia was assessed by the Eating Assessment Tool (EAT-10) and the Volume-Viscosity Swallow Test (V-VST). The Food Frequency Questionnaire and the Swallowing Quality of Life Questionnaire were used to assess dietary intake and QoL, respectively.

Results: Thirty women with FMS were at risk for dysphagia (65.21%), assessed by the EAT-10. Based on the V-VST, the frequency of risk of dysphagia was 63.04%. Significant differences in body mass index (BMI) were found between women at risk for dysphagia and those without risk. Women at risk for dysphagia had significantly lower overall QoL scores than those women without risk. No significant differences were found for dietary intake and dysphagia risk.

Discussion: Women with FMS at risk for dysphagia have significantly lower BMI values and worse QoL than women without dysphagia risk, supporting the importance of assessing dysphagia in clinical practice in persons with FMS.

背景:纤维肌痛综合征(FMS)是一种特发性慢性疾病,以广泛的肌肉骨骼疼痛、痛觉减退和异感为特征,最近被发现与吞咽困难的风险有关:我们的目的是分析与无吞咽困难风险的 FMS 女性患者相比,FMS 女性患者队列中的营养状况、微量和宏量营养素摄入与生活质量(QoL)之间的关系:对 46 名患有 FMS 的女性进行了横断面研究。吞咽困难风险通过进食评估工具(EAT)和体积-粘度测试(V-VST)进行评估。食物频率问卷和吞咽生活质量问卷分别用于评估饮食摄入量和生活质量:根据 EAT-10 评估,30 名患有 FMS 的妇女(65.21%)有吞咽困难的风险。根据 V-VST 评估,有吞咽困难风险的频率为 63.04%。有吞咽困难风险的妇女与无吞咽困难风险的妇女在体重指数(BMI)方面存在显著差异。有吞咽困难风险的妇女的总体 QoL 评分明显低于无吞咽困难风险的妇女。在饮食摄入量和吞咽困难风险方面没有发现明显差异:讨论:与无吞咽困难风险的女性相比,有吞咽困难风险的 FMS 女性患者的 BMI 值明显较低,QoL 也较差,这证明了在临床实践中对 FMS 患者进行吞咽困难评估的重要性。
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引用次数: 0
Mediating Role of Rumination in Second Victim Experience to Turnover Intention in Psychiatric Nurses. 精神科护士第二次受害经历中的反刍对离职意向的中介作用。
IF 2.2 4区 医学 Q1 NURSING Pub Date : 2024-05-01 Epub Date: 2024-01-31 DOI: 10.1097/NNR.0000000000000715
Yanru Shao, Xinzhi Shan, Shanshan Li, Xinwei Zhang, Kun Chi, Yingxuan Xu, Holly Wei

Background: Psychiatric nurses often face patient safety incidents that can cause physical and emotional harm, even leading to s econd victim syndrome and staff shortages. Rumination-a common response after nurses suffer a patient safety event-may play a specific role between the second victim experience and turnover intention. Understanding these mechanisms is crucial for supporting psychiatric nurses and retaining psychiatric nursing resources.

Objectives: The study aimed to explore the associations among second victim experience, rumination, and turnover intention in psychiatric nurses and confirm how second victim experience influences turnover intention through rumination and its subtypes.

Methods: A descriptive, cross-sectional study was adapted to survey 252 psychiatric nurses who experienced a patient safety incident at three hospitals in China between March and April 2023. We used the Sociodemographic and Patient Safety Incident Characteristics Questionnaire (the Chinese version of the Second Victim Experience and Support Tool), the Event-Related Rumination Inventory, and the Turnover Intention Scale. Path analysis with bootstrapping was employed to accurately analyze and estimate relationships among the study variables.

Results: There was a positive association between second victim experience and turnover intention. In addition, both invasive and deliberate rumination showed significant associations with second victim experience and turnover intention. Notably, our results revealed that invasive and deliberate rumination played partial mediating roles in the relationship between second victim experience and turnover intention in psychiatric nurses.

Discussion: The negative experience and turnover intention of the psychiatric nurse second victims are at a high level. Our results showed that invasive rumination positively mediated the relationship between second victim experience and turnover intention, and deliberate rumination could weaken this effect. This study expands the knowledge of the mechanisms underlying the effect of the second victim experience on turnover intention. Organizations must attach importance to the professional dilemmas of the psychiatric nurses' second victims. Nurse managers can reduce nurses' turnover intention by taking measures to reduce invasive rumination and fostering deliberate meditation to help second victims recover from negative experiences.

背景:精神科护士经常面临患者安全事件,这些事件可能会对其造成身体和精神伤害,甚至导致第二受害者综合征和人员短缺。反刍--护士在遭遇患者安全事件后的常见反应--可能在第二受害者经历和离职意向之间起着特定的作用。了解这些机制对于支持精神科护士和保留精神科护理资源至关重要:本研究旨在探讨精神科护士的二次伤害经历、反刍和离职意向之间的关联,并确认二次伤害经历如何通过反刍及其亚型影响离职意向:采用描述性横断面研究方法,调查了 2023 年 3 月至 4 月间在中国三家医院经历过患者安全事件的 252 名精神科护士。我们使用了社会人口学和患者安全事件特征问卷--第二受害者体验和支持工具中文版--事件相关反刍量表和离职意向量表。为了准确分析和估计研究变量之间的关系,采用了带引导的路径分析方法:结果:第二次受害经历与离职意向之间存在正相关。此外,入侵性反刍和蓄意反刍都与第二次受害经历和离职意向有显著关联。值得注意的是,我们的研究结果显示,侵入性反刍和蓄意反刍在精神科护士的二次伤害经历与离职意向之间的关系中起到了部分中介作用:讨论:精神科护士第二受害者的负面经历和离职意向处于较高水平。我们的研究结果表明,入侵性反刍对第二受害者经历和离职意向之间的关系起着积极的中介作用,而蓄意反刍会削弱这种作用。这项研究拓展了人们对第二受害者经历对离职意向影响机制的认识。组织必须重视精神科护士第二受害者的职业困境。护士管理者可以通过采取措施减少侵入性反刍和促进刻意冥想来帮助第二受害者从负面经历中恢复,从而降低护士的离职意向。
{"title":"Mediating Role of Rumination in Second Victim Experience to Turnover Intention in Psychiatric Nurses.","authors":"Yanru Shao, Xinzhi Shan, Shanshan Li, Xinwei Zhang, Kun Chi, Yingxuan Xu, Holly Wei","doi":"10.1097/NNR.0000000000000715","DOIUrl":"10.1097/NNR.0000000000000715","url":null,"abstract":"<p><strong>Background: </strong>Psychiatric nurses often face patient safety incidents that can cause physical and emotional harm, even leading to s econd victim syndrome and staff shortages. Rumination-a common response after nurses suffer a patient safety event-may play a specific role between the second victim experience and turnover intention. Understanding these mechanisms is crucial for supporting psychiatric nurses and retaining psychiatric nursing resources.</p><p><strong>Objectives: </strong>The study aimed to explore the associations among second victim experience, rumination, and turnover intention in psychiatric nurses and confirm how second victim experience influences turnover intention through rumination and its subtypes.</p><p><strong>Methods: </strong>A descriptive, cross-sectional study was adapted to survey 252 psychiatric nurses who experienced a patient safety incident at three hospitals in China between March and April 2023. We used the Sociodemographic and Patient Safety Incident Characteristics Questionnaire (the Chinese version of the Second Victim Experience and Support Tool), the Event-Related Rumination Inventory, and the Turnover Intention Scale. Path analysis with bootstrapping was employed to accurately analyze and estimate relationships among the study variables.</p><p><strong>Results: </strong>There was a positive association between second victim experience and turnover intention. In addition, both invasive and deliberate rumination showed significant associations with second victim experience and turnover intention. Notably, our results revealed that invasive and deliberate rumination played partial mediating roles in the relationship between second victim experience and turnover intention in psychiatric nurses.</p><p><strong>Discussion: </strong>The negative experience and turnover intention of the psychiatric nurse second victims are at a high level. Our results showed that invasive rumination positively mediated the relationship between second victim experience and turnover intention, and deliberate rumination could weaken this effect. This study expands the knowledge of the mechanisms underlying the effect of the second victim experience on turnover intention. Organizations must attach importance to the professional dilemmas of the psychiatric nurses' second victims. Nurse managers can reduce nurses' turnover intention by taking measures to reduce invasive rumination and fostering deliberate meditation to help second victims recover from negative experiences.</p>","PeriodicalId":49723,"journal":{"name":"Nursing Research","volume":" ","pages":"E21-E30"},"PeriodicalIF":2.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139652004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nursing Science: This I (Still) Believe. 护理科学:这一点我(仍然)相信。
IF 2.2 4区 医学 Q1 NURSING Pub Date : 2024-05-01 DOI: 10.1097/NNR.0000000000000728
Mihkaila Maurine Wickline
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引用次数: 0
Construct Validity Testing of the Provider Co-Management Index to Measure Shared Care in Provider Dyads. 测试 "医疗服务提供者共同管理指数 "的结构有效性,以衡量医疗服务提供者二人组中的共同护理。
IF 2.2 4区 医学 Q1 NURSING Pub Date : 2024-05-01 Epub Date: 2024-02-06 DOI: 10.1097/NNR.0000000000000719
Allison A Norful, Andrew Dierkes, Krystyna de Jacq, Katherine C Brewer

Background: Co-management encompasses the dyadic process between two healthcare providers. The Provider Co-Management Index (PCMI) was initially developed as a 20-item instrument across three theory-informed subscales.

Objective: This study aimed to establish construct validity of the PCMI with a sample of primary care providers through exploratory and confirmatory factor analyses.

Methods: We conducted a cross-sectional survey of primary care physicians, nurse practitioners, and physician assistants randomly selected from the IQVIA database across New York State. Mail surveys were used to acquire a minimum of 300 responses for split sample factor analyses. The first subsample (derivation sample) was used to explore factorial structure by conducting an exploratory factor analysis. A second (validation) sample was used to confirm the emerged factorial structure using confirmatory factor analysis. We performed iterative analysis and calculated good fit indices to determine the best-fit model.

Results: There were 333 responses included in the analysis. Cronbach's alpha was high for a three-item per dimension scale within a one-factor model. The instrument was named PCMI-9 to indicate the shorter version length.

Discussion: This study established the construct validity of an instrument that scales the co-management of patients by two providers. The final instrument includes nine items on a single factor using a 4-point, Likert-type scale. Additional research is needed to establish discriminant validity.

背景:共同管理包括两个医疗服务提供者之间的合作过程。医疗服务提供者共同管理指数(PCMI)最初是作为一个包含 20 个项目的工具而开发的,其中包含三个基于理论的子量表:本研究旨在通过探索性和确认性因素分析,在初级医疗服务提供者样本中建立 PCMI 的构建有效性:我们对从纽约州 IQVIA 数据库中随机抽取的全科医师、执业护士和助理医师进行了横断面调查。通过邮寄调查至少获得了 300 份回复,以便进行分离样本因子分析。第一个子样本(衍生样本)用于通过进行探索性因子分析来探索因子结构。第二个子样本(验证样本)用于通过确认性因子分析确认已出现的因子结构。我们进行了迭代分析,并计算了拟合指数,以确定最佳拟合模型:共有 333 个回答被纳入分析。对于单因素模型中每个维度 3 个项目的量表而言,Cronbach's alpha 很高。该量表被命名为 PCMI-9,以表示较短的版本长度:本研究确定了一种工具的构建效度,该工具可对两名医疗服务提供者共同管理患者的情况进行评分。最终的工具包括 9 个项目,采用李克特(Likert)式 4 点量表的单因子。还需要进行更多的研究来确定判别效度。
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引用次数: 0
Cigarette and E-Cigarette Perceptions About Harm During Pregnancy. 孕期对卷烟和电子烟危害的看法。
IF 2.5 4区 医学 Q1 NURSING Pub Date : 2024-04-10 DOI: 10.1097/nnr.0000000000000742
Rebecca McCann, Emily Richardson, Eric D Schisler, Abbie Sudduth, Page D Dobbs
Research suggests that pregnancy status (prior, current, and future intention) is associated with differences in perceived harm of e-cigarette use during pregnancy. However, perceptions of health outcomes attributed to cigarette and e-cigarette use during pregnancy have not been explored among a sample of pregnant women who smoke.
研究表明,怀孕状态(之前、现在和未来的意向)与孕期使用电子烟的危害感知差异有关。然而,在吸烟孕妇样本中,还没有人对孕期使用香烟和电子烟造成的健康后果进行过研究。
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引用次数: 0
Health Misinformation and Nursing Science. 健康误导与护理科学。
IF 2.2 4区 医学 Q1 NURSING Pub Date : 2024-03-01 Epub Date: 2023-12-17 DOI: 10.1097/NNR.0000000000000711
Rita H Pickler
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引用次数: 0
Salivary Cortisol and Melatonin, Sleep, and Behavioral Patterns in Older Adults Living With Dementia. 老年痴呆症患者的唾液皮质醇和褪黑激素、睡眠和行为模式。
IF 2.2 4区 医学 Q1 NURSING Pub Date : 2024-03-01 Epub Date: 2023-12-18 DOI: 10.1097/NNR.0000000000000709
Eunhee Cho, Hyangkyu Lee, Jinhee Shin, Sujin Kim, Seok-Jae Heo, Hyunki Park, Jo Woon Seok

Background: Over half of the older adults living with dementia have behavioral and psychological symptoms of dementia (BPSD), including sleep disturbance; however, little is known about physiological markers. Salivary cortisol and melatonin have been identified as potential biomarkers of BPSD, with evidence suggesting a relationship between these biomarkers and various behavioral factors, as well as sleep and activity patterns.

Objectives: The aim of this study was to investigate the time-dependent changes in salivary cortisol and melatonin levels in older adults with dementia, their relationship with the sleep-wake cycle, and their correlation with BPSD symptoms and behavioral factors.

Methods: This observational study conducted in Seoul and Gyeonggi-do, South Korea, used data from 172 older adults with dementia, measuring sleep and activity patterns for 2 weeks using a wearable device, in addition to administering questionnaires for neuropsychiatric and psychological symptoms-the Neuropsychiatric Inventory, Cohen-Mansfield Agitation Inventory, and Cornell Scale for Depression in Dementia. Salivary cortisol and melatonin levels were measured at four time points and divided into four groups based on a dual-trajectory model. Differences among the groups were analyzed using one-way analysis of variance.

Results: The participants showed normal but heterogeneous patterns of salivary cortisol and melatonin levels. Dual-trajectory pattern analysis showed that higher levels of melatonin during the daytime were correlated with poor nighttime sleep efficiency and decreased disinhibited behaviors, and higher levels of cortisol at all four time points were associated with decreased physical activity.

Discussion: Measuring and analyzing periodic changes in cortisol and melatonin levels can predict various behavioral symptoms (e.g., sleep disturbances, activity counts, and disinhibition) in older adults with dementia. A study with an experimental design is needed to discover the direct physiological interactions between cortisol, melatonin, and these symptoms.

背景:半数以上患有痴呆症的老年人有痴呆症的行为和心理症状(BPSD),包括睡眠障碍;然而,人们对这些生理标志物知之甚少。唾液皮质醇和褪黑激素已被确定为 BPSD 的潜在生物标志物,有证据表明这些生物标志物与各种行为因素以及睡眠和活动模式之间存在关系:研究老年痴呆症患者唾液皮质醇和褪黑激素水平随时间的变化、它们与睡眠-觉醒周期的关系以及它们与BPSD症状和行为因素的相关性:这项在韩国首尔和京畿道进行的观察性研究使用了 172 名老年痴呆症患者的数据,使用可穿戴设备测量了他们两周的睡眠和活动模式,此外还进行了神经精神症状和心理症状问卷调查--神经精神症状量表、科恩-曼斯菲尔德躁动量表和康奈尔老年痴呆症抑郁量表。在四个时间点测量唾液皮质醇和褪黑激素水平,并根据双重轨迹模型将其分为四组。各组之间的差异采用单因素方差分析法进行分析:结果:参与者的唾液皮质醇和褪黑激素水平正常,但存在差异。双重轨迹模式分析显示,白天褪黑激素水平较高与夜间睡眠效率低和抑制行为减少有关,而在所有四个时间点皮质醇水平较高与体力活动减少有关:讨论:测量和分析皮质醇和褪黑激素水平的周期性变化可以预测老年痴呆症患者的各种行为症状(如睡眠障碍、活动次数和抑制)。需要进行实验设计研究,以发现皮质醇、褪黑激素与这些症状之间的直接生理相互作用。
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引用次数: 0
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Nursing Research
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