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Successful Radiosurgical Treatment of Lesional Epilepsy of Mesial Temporal Origin 颞内缘病变性癫痫的成功放射外科治疗
Pub Date : 2001-03-01 DOI: 10.1055/s-2001-13586
H. Kurita1, I. Suzuki1, M. Shin1, K. Kawai1, M. Tago2, T. Momose2, T. Kirino1
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引用次数: 19
Association Between Decreased Disc Signal Intensity in Preoperative T2-Weighted MRI and a 5-Year Outcome after Lumbar Minimally Invasive Discectomy 术前t2加权MRI椎间盘信号强度降低与腰椎微创椎间盘切除术后5年预后的关系
Pub Date : 2001-03-01 DOI: 10.1055/s-2001-13584
E. Kotilainen1, A. Alanen2, M. Erkintalo2, S. Valtonen1, M. Kormano2
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引用次数: 14
Endoscopic Endonasal Pituitary Surgery: Evolution of Surgical Technique and Equipment in 150 Operations 鼻内窥镜垂体手术:150例手术中手术技术和设备的发展
Pub Date : 2001-03-01 DOI: 10.1055/s-2001-13590
Jho Hd, A. Alfieri
Objective: Methods: Results: Conclusions:
目的:方法:结果:
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引用次数: 160
Endoscopic Surgery for Large Posterior Fossa Arachnoid Cysts 后窝大蛛网膜囊肿的内镜手术治疗
Pub Date : 2001-03-01 DOI: 10.1055/s-2001-13588
M. Gangemi, F. Maiuri, G. Colella, L. Sardo
The authors report two cases of large arachnoid cysts of the posterior fossa treated by endoscopic surgery. One patient underwent a successful endoscopic cyst fenestration by burr hole approach after several procedures of shunt revision. In another an endoscope-assisted microsurgical intervention was necessary. Lateral (cerebellar or cerebellopontine angle) cysts, as two reported cases, may be treated through a lateral retromastoid approach by fenestration into the prepontine cistern and eventually into the cisterna magna. We advise to start the operation through a burr hole and to try to realize the fenestration by endoscopy only. If this attempt fails, an endoscope-assisted microsurgical technique may be performed by enlarging the craniectomy. In this last instance the endoscope is useful particularly deeply to fenestrate the anterior cyst wall in the prepontine or ambient cisterns, where it provides more illumination and helps to identify the nervous and vascular structures.
作者报告两例后窝大蛛网膜囊肿的内镜手术治疗。一名患者在经过多次分流翻修手术后,通过钻孔入路成功进行了内窥镜囊肿开窗手术。在另一种情况下,内窥镜辅助显微手术干预是必要的。外侧(小脑或桥小脑角)囊肿,作为两个报告的病例,可以通过侧乳突后入路,通过开窗进入前池,最终进入大池。我们建议从一个毛刺孔开始手术,并尝试仅通过内窥镜来实现开窗。如果这种尝试失败,内窥镜辅助显微手术技术可以通过扩大颅骨切除术来进行。在最后一种情况下,内窥镜在探查前池或周围池的囊肿壁时特别有用,在那里它提供了更多的照明,并有助于识别神经和血管结构。
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引用次数: 31
The Impact of an Armless Frameless Neuronavigation System on Routine Brain Tumour Surgery: A Prospective Analysis of 51 Cases 无臂无框架神经导航系统对常规脑肿瘤手术的影响:51例前瞻性分析
Pub Date : 2001-02-01 DOI: 10.1055/s-2001-15998
G. Wong, W. Poon, M. Lam
A passive infrared armless and frameless neuronavigation system was introduced in routine intracranial and skull base surgery, and its impact on 51 cases in a one year period was assessed. No cases were rejected by the operating surgeon for lack of accuracy (> 3 mm). Operating time was not significantly lengthened, except in transphenoidal cases (255 +/- SD 168 min versus 185 +/- SD 119 min, p = 0.02). Length of stay was shorter in navigation cases in supratentorial glioma (12 +/- SD 7.3 days versus 15 +/- SD 7.9 days) and meningioma (11 +/- SD 5.3 days versus 16 +/- SD 6.7 days, p = 0.01). Outcome at 3 months was comparable in both the supratentorial glioma and meningioma group. Problems such as setup time and brain shift are addressed and discussed.
将被动红外无臂无框架神经导航系统应用于颅底常规手术,对51例患者1年的临床效果进行了评价。没有病例因精确度不足(> 3mm)而被手术医生拒绝。除经蝶窦病例外,手术时间无明显延长(255 +/- SD 168 min vs 185 +/- SD 119 min, p = 0.02)。导航组幕上胶质瘤(12 +/- SD 7.3天,15 +/- SD 7.9天)和脑膜瘤(11 +/- SD 5.3天,16 +/- SD 6.7天,p = 0.01)的住院时间较短。幕上胶质瘤组和脑膜瘤组在3个月时的结果是相似的。讨论了设置时间和大脑转移等问题。
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引用次数: 25
Early Effects of PRS-Irradiation for 9L Gliosarcoma: Characterization of Interphase Cell Death prs照射对9L胶质瘤的早期影响:间期细胞死亡的表征
Pub Date : 2000-12-01 DOI: 10.1055/s-2000-11373
H. Kurita, Ostertag Cb, B. Baumer, K. Kopitzki, P. Warnke
We characterized the interphase cell death of 9L gliosarcoma after high-dose-rate, low-energy photon irradiation using the Photon Radiosurgery System (PRS), a novel device for interstitial radiotherapy. Within 24 hours after irradiation with a dose of 18 Gray, 22.0% of cells underwent metabolic cell death, whereas dead cells in controls stayed less than 5.0% (p<0.005). In the majority of sensitive cells, loss of membrane integrity preceded the lethal morphological changes. The response was dose-dependent over the range of 9-18 Gray, but saturation was obtained over 18 Gray. On the other hand, a significant (p < 0.01) increase in the number of TUNEL-positive cells with apoptotic morphology was detected 6-24 hours after irradiation, but the fraction remained 1.9-2.1% of the population and was independent of the doses between 9 and 25 Gray. Apoptotic cells were rarely observed in the control cells (0.3-0.6%). Our data indicate that single high-dose irradiation induces both necrotic and apoptotic interphase cell death in 9L gliosarcoma, but rapid cell death mostly occurs through the non-apoptotic pathway.
我们使用光子放射外科系统(PRS),一种用于间质放疗的新型设备,描述了高剂量率,低能量光子照射后9L胶质肉瘤间期细胞死亡。在18 Gray剂量照射后24小时内,22.0%的细胞发生代谢性细胞死亡,而对照组的死亡细胞低于5.0% (p<0.005)。在大多数敏感细胞中,细胞膜完整性的丧失先于致死性形态学改变。在9-18 Gray范围内,反应是剂量依赖性的,但在18 Gray范围内达到饱和。另一方面,辐照后6 ~ 24 h tunel阳性细胞呈凋亡形态的数量显著增加(p < 0.01),但仍占总细胞数的1.9 ~ 2.1%,且与9 ~ 25 Gray剂量无关。对照细胞中很少见凋亡细胞(0.3-0.6%)。我们的数据表明,单次高剂量照射可诱导9L胶质肉瘤的坏死和凋亡间期细胞死亡,但快速细胞死亡主要通过非凋亡途径发生。
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引用次数: 12
Relationships of Virtual Reality Neuroendoscopic Simulations to Actual Imaging 虚拟现实神经内窥镜模拟与实际成像的关系
Pub Date : 2000-12-01 DOI: 10.1055/s-2000-11375
T. Riegel1, O. Alberti1, R. Retsch1, V. Shiratori2, D. Hellwig1, H. Bertalanffy1
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引用次数: 32
Gamma Knife Radiosurgery of the Brain Stem Cavernomas 脑干海绵状瘤的伽玛刀放射治疗
Pub Date : 2000-12-01 DOI: 10.1055/s-2000-11378
R. Liščák, V. Vladyka, G. Simonova, J. Vymazal, J. Novotný
Over 6 years (1992-1998) 26 patients with brain stem cavernomas were treated using the Leksell gamma knife in Prague. 25 patients had a follow up of 6-66, median 24 months. Annual risk of bleeding before radiosurgery was 4%. After gamma knife treatment sudden impairment of neurodeficit reported as rebleeding was observed in 4 patients at 6-51 months, median 16.5 months, after radiosurgery. This represented a 6.8% risk of rebleeding after radiosurgery, which is not significantly different from the risk before radiosurgery. MRI or CT was performed in 24 patients 6-48, median 24, months after radiosurgery. There were no signs of rebleeding in any of the patients, nor any increase of the cavernoma. A decrease of cavernoma size was observed in 8 (33%) of patients. Temporary collateral edema after radiosurgery was detected in 5 (21%) of patients 3-12, median 11, months after radiosurgery. Neurodeficit was observed in 21 of 26 patients before radiosurgery. Improvement of the neurodeficit was detected in 9 (43%) of them 6-36, median 8, months after radiosurgery. Temporary morbidity caused by collateral edema or rebleeding occurred in 7 patients (28%) and permanent morbidity remained in 2 patients (8%). 2 patients died because of rebleeding 6 and 51 months after radiosurgery and the third patient for unrelated reason. Radiosurgery of the brain stem cavernomas was indicated when there was bleeding in the history or progressive neurodeficit and microsurgery was considered too risky. Leksell gamma knife radiosurgery of cavernomas has proved its low morbidity and zero mortality. In case of an insufficient effect of radiosurgery, or if the protective effect from rebleeding comes too late, morbidity and mortality can correspond to the natural course of the disease, as it was left without any treatment.
在6年间(1992-1998),26例脑干海绵瘤患者在布拉格使用Leksell伽玛刀治疗,25例患者随访6-66个月,中位随访24个月。放疗前出血的年风险为4%。在伽玛刀治疗后,4例患者在放疗后6-51个月(中位16.5个月)观察到突发性神经缺损损伤,报告为再出血。这意味着放疗后再出血的风险为6.8%,与放疗前的风险没有显著差异。24例患者术后6 ~ 48个月(中位24个月)行MRI或CT检查。所有的病人都没有再出血的迹象,也没有海绵状瘤的增加。8例(33%)患者的海绵瘤体积减小。5例(21%)患者在放疗后3-12个月(中位11个月)出现暂时性侧支水肿。26例患者放疗前有21例出现神经缺损。其中9例(43%)在放疗后6-36个月(中位8个月)神经功能缺损得到改善。7例(28%)患者出现侧支水肿或再出血引起的暂时性发病,2例(8%)患者出现永久性发病。2例因术后6月和51月再出血死亡,3例因无关原因死亡。当脑干海绵状瘤有出血史或进行性神经缺损,显微手术风险太大时,应行放射线手术。Leksell伽玛刀放射治疗海绵状瘤已证明其低发病率和零死亡率。如果放射手术效果不足,或者防止再出血的保护作用来得太晚,发病率和死亡率可以与疾病的自然过程相对应,因为它没有得到任何治疗。
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引用次数: 40
Transient Hyponatriemia Complicated by Seizures after Endoscopic Third Ventriculostomy 内镜下第三脑室造口术后短暂性低钠血症并发癫痫发作
Pub Date : 2000-12-01 DOI: 10.1055/s-2000-11371
C. Vaicys1, A. Fried2
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引用次数: 34
Titanium Clamps for Refixation of Bone Fragments in the Repair of Depressed Skull Fractures: Technical Note 在颅骨凹陷骨折修复中用于骨碎片再固定的钛夹:技术要点
Pub Date : 2000-12-01 DOI: 10.1055/s-2000-11380
H. Ebel1, G. Schillinger1, C. Walter2, H. Brockhagen2, N. Klug1
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引用次数: 9
期刊
Minimally Invasive Neurosurgery
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