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COVID-19 Pandemic's Effects on Occupational Health and Perceived Work Ability of a Large Group of Italian Banking Employees.
IF 2.4 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-19 DOI: 10.23749/mdl.v115i6.15848
Marco Mendola, Marco Leoni, Giuseppe Marano, Maurizio Coggiola, Dario Russignaga, Elia Biganzoli, Paolo Carrer

Background: The COVID-19 pandemic compelled changes to the structure and organization of many occupational sectors that may impact workers' well-being and work-related symptoms.

Objective: Evaluate the effects of working modifications related to the COVID-19 pandemic on occupational health outcomes and work ability (WA) among a large group of Italian banking employees.

Methods: 2,859 employees visited during health surveillance in 2021 were divided into two job groups: front-office (FO) and back-office workers (BO). Data on conditions associated with office work, psychological distress, WA, and fitness-to-work judgment were analyzed and compared with available data from the pre-pandemic period (2018-2019).

Results: The prevalence of analyzed outcomes was lower than in pre- and post-COVID evaluation literature. After COVID-19, a 28% increase in asthenopin was found in BO, while musculoskeletal symptoms increased about 22% in BO and 9% in FO. Post-COVID showed a 28% rise in stress-related symptoms and a 17% increase in psychotropic drug consumption in both groups. After the lockdown, the prevalence of moderate/poor scores decreased by 13% in each group. Fitness-to-work judgment without limitations prevalence was unchanged.

Conclusion: The slight worsening in all examined outcomes at post-lockdown evaluation and the outcomes' prevalence consistently lower than the literature data could be linked to the measures the Institute took to support employees during the COVID-19 pandemic. In this context, a comprehensive integration between occupational safety and health promotion practices is recommended to ensure the highest level of safeguarding for workers' well-being.

{"title":"COVID-19 Pandemic's Effects on Occupational Health and Perceived Work Ability of a Large Group of Italian Banking Employees.","authors":"Marco Mendola, Marco Leoni, Giuseppe Marano, Maurizio Coggiola, Dario Russignaga, Elia Biganzoli, Paolo Carrer","doi":"10.23749/mdl.v115i6.15848","DOIUrl":"10.23749/mdl.v115i6.15848","url":null,"abstract":"<p><strong>Background: </strong>The COVID-19 pandemic compelled changes to the structure and organization of many occupational sectors that may impact workers' well-being and work-related symptoms.</p><p><strong>Objective: </strong>Evaluate the effects of working modifications related to the COVID-19 pandemic on occupational health outcomes and work ability (WA) among a large group of Italian banking employees.</p><p><strong>Methods: </strong>2,859 employees visited during health surveillance in 2021 were divided into two job groups: front-office (FO) and back-office workers (BO). Data on conditions associated with office work, psychological distress, WA, and fitness-to-work judgment were analyzed and compared with available data from the pre-pandemic period (2018-2019).</p><p><strong>Results: </strong>The prevalence of analyzed outcomes was lower than in pre- and post-COVID evaluation literature. After COVID-19, a 28% increase in asthenopin was found in BO, while musculoskeletal symptoms increased about 22% in BO and 9% in FO. Post-COVID showed a 28% rise in stress-related symptoms and a 17% increase in psychotropic drug consumption in both groups. After the lockdown, the prevalence of moderate/poor scores decreased by 13% in each group. Fitness-to-work judgment without limitations prevalence was unchanged.</p><p><strong>Conclusion: </strong>The slight worsening in all examined outcomes at post-lockdown evaluation and the outcomes' prevalence consistently lower than the literature data could be linked to the measures the Institute took to support employees during the COVID-19 pandemic. In this context, a comprehensive integration between occupational safety and health promotion practices is recommended to ensure the highest level of safeguarding for workers' well-being.</p>","PeriodicalId":49833,"journal":{"name":"Medicina Del Lavoro","volume":"115 6","pages":"e2024038"},"PeriodicalIF":2.4,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11734631/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142856368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reliability and Validity of the Turkish Version of Work-Related Questionnaire for Upper Extremity Disorders (WORQ-UP).
IF 2.4 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-19 DOI: 10.23749/mdl.v115i6.15991
Meltem Koç, Cansu Dal, Emin Kürşat Bulut, Banu Bayar, Kılıçhan Bayar

Background: The Work-Related Questionnaire for Upper Extremity Disorders (WORQ-UP) serves as a patient-reported outcome measure to identify work-related limitations in individuals with upper extremity musculoskeletal disorders. This study aims to adapt the WORQ-UP into Turkish and subsequently evaluate its validity and reliability.

Methods: The Turkish WORQ-UP, along with the previously validated Turkish Quick DASH, were administered to 136 patients. The Turkish WORQ-UP was applied twice within a 7-14 day interval to assess test-retest reliability. Reliability was assessed using measures of internal consistency and intraclass correlation coefficient (ICC). For validity assessment, Spearman correlation coefficients were calculated between the Turkish WORQ-UP and Quick DASH, and Explanatory (EFA) and Confirmatory factor analysis (CFA) were conducted.

Results:  In the reliability analysis, items 11, 12, 13, 15, and 16, which did not meet the criterion of item total score correlation >30, were excluded, resulting in a 12-item Turkish WORQ-UP with satisfactory validity and reliability outcomes. The Cronbach's alpha and ICC were calculated as 0.895 and 0.879, respectively, while the SEM and MDC were determined to be 0.93 and 1.85. In the EFA, the Kaiser-Meyer-Olkin measure (0.895) and Bartlett's tests were both significant (p < 0.001). Additionally, the CFA indicated an acceptable fit with two factors. The goodness of fit indices, including χ2/df = 2.09, CFI = 0.934, TLI = 0.918, and RMSEA = 0.08, confirmed the adequacy of the model. The 12-item Turkish WORQ-UP showed a significant and strong correlation (r = 0.754; p < 0.001) with Quick DASH.

Conclusion: The Turkish version of WORQ-UP with 12 items had proper psychometric properties to identify work-related limitations in individuals with upper extremity musculoskeletal disorders.

{"title":"Reliability and Validity of the Turkish Version of Work-Related Questionnaire for Upper Extremity Disorders (WORQ-UP).","authors":"Meltem Koç, Cansu Dal, Emin Kürşat Bulut, Banu Bayar, Kılıçhan Bayar","doi":"10.23749/mdl.v115i6.15991","DOIUrl":"10.23749/mdl.v115i6.15991","url":null,"abstract":"<p><strong>Background: </strong>The Work-Related Questionnaire for Upper Extremity Disorders (WORQ-UP) serves as a patient-reported outcome measure to identify work-related limitations in individuals with upper extremity musculoskeletal disorders. This study aims to adapt the WORQ-UP into Turkish and subsequently evaluate its validity and reliability.</p><p><strong>Methods: </strong>The Turkish WORQ-UP, along with the previously validated Turkish Quick DASH, were administered to 136 patients. The Turkish WORQ-UP was applied twice within a 7-14 day interval to assess test-retest reliability. Reliability was assessed using measures of internal consistency and intraclass correlation coefficient (ICC). For validity assessment, Spearman correlation coefficients were calculated between the Turkish WORQ-UP and Quick DASH, and Explanatory (EFA) and Confirmatory factor analysis (CFA) were conducted.</p><p><strong>Results: </strong> In the reliability analysis, items 11, 12, 13, 15, and 16, which did not meet the criterion of item total score correlation >30, were excluded, resulting in a 12-item Turkish WORQ-UP with satisfactory validity and reliability outcomes. The Cronbach's alpha and ICC were calculated as 0.895 and 0.879, respectively, while the SEM and MDC were determined to be 0.93 and 1.85. In the EFA, the Kaiser-Meyer-Olkin measure (0.895) and Bartlett's tests were both significant (p < 0.001). Additionally, the CFA indicated an acceptable fit with two factors. The goodness of fit indices, including χ2/df = 2.09, CFI = 0.934, TLI = 0.918, and RMSEA = 0.08, confirmed the adequacy of the model. The 12-item Turkish WORQ-UP showed a significant and strong correlation (r = 0.754; p < 0.001) with Quick DASH.</p><p><strong>Conclusion: </strong>The Turkish version of WORQ-UP with 12 items had proper psychometric properties to identify work-related limitations in individuals with upper extremity musculoskeletal disorders.</p>","PeriodicalId":49833,"journal":{"name":"Medicina Del Lavoro","volume":"115 6","pages":"e2024040"},"PeriodicalIF":2.4,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11734634/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142856392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adapting the HSE-MS Indicator Tool for Academia: A Psychometric Evaluation of the Academic Teacher Stress Indicator Tool in Italian.
IF 2.4 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-19 DOI: 10.23749/mdl.v115i6.16294
Francesco Marcatto, Donatella Ferrante, Lisa Di Blas, Francesca Larese Filon

Background: The assessment of work-related stress is mandatory in Italy, according to Legislative Decree 81/2008. The Academic Teacher Stress Indicator Tool (ATS-IT) was developed to address stress in academic teaching staff by adapting the Health and Safety Executive Management Standards Indicator Tool (HSE-MS IT).

Methods: An online ATS-IT survey was administered to all teaching staff at the University of Trieste, yielding 334 valid responses. The survey also included a measure of psychosomatic complaints and demographic questions. Confirmatory factor analysis (CFA) was performed to test the six-factor structure, and reliability was assessed using Cronbach's alpha.

Results: CFA confirmed an excellent fit for the six-factor structure (CFI = .99; TLI = .99; RMSEA = .034). Reliability analysis mainly showed acceptable values (Cronbach's α ranging from .66 to .91). Significant gender differences were found in the Demands and Control scales, with additional differences based on age and academic role across multiple scales. The ATIS-IT scales were significantly intercorrelated and negatively correlated with psychosomatic complaints.

Conclusions: The ATS-IT demonstrates good potential as a valid and reliable instrument for assessing work-related stress among Italian academic teaching staff. Its use can facilitate better stress management and intervention strategies in educational institutions.

{"title":"Adapting the HSE-MS Indicator Tool for Academia: A Psychometric Evaluation of the Academic Teacher Stress Indicator Tool in Italian.","authors":"Francesco Marcatto, Donatella Ferrante, Lisa Di Blas, Francesca Larese Filon","doi":"10.23749/mdl.v115i6.16294","DOIUrl":"10.23749/mdl.v115i6.16294","url":null,"abstract":"<p><strong>Background: </strong>The assessment of work-related stress is mandatory in Italy, according to Legislative Decree 81/2008. The Academic Teacher Stress Indicator Tool (ATS-IT) was developed to address stress in academic teaching staff by adapting the Health and Safety Executive Management Standards Indicator Tool (HSE-MS IT).</p><p><strong>Methods: </strong>An online ATS-IT survey was administered to all teaching staff at the University of Trieste, yielding 334 valid responses. The survey also included a measure of psychosomatic complaints and demographic questions. Confirmatory factor analysis (CFA) was performed to test the six-factor structure, and reliability was assessed using Cronbach's alpha.</p><p><strong>Results: </strong>CFA confirmed an excellent fit for the six-factor structure (CFI = .99; TLI = .99; RMSEA = .034). Reliability analysis mainly showed acceptable values (Cronbach's α ranging from .66 to .91). Significant gender differences were found in the Demands and Control scales, with additional differences based on age and academic role across multiple scales. The ATIS-IT scales were significantly intercorrelated and negatively correlated with psychosomatic complaints.</p><p><strong>Conclusions: </strong>The ATS-IT demonstrates good potential as a valid and reliable instrument for assessing work-related stress among Italian academic teaching staff. Its use can facilitate better stress management and intervention strategies in educational institutions.</p>","PeriodicalId":49833,"journal":{"name":"Medicina Del Lavoro","volume":"115 6","pages":"e2024041"},"PeriodicalIF":2.4,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11734635/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142856382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Human Exposure to Asbestos in Central Asian Countries and Health Effects: A Narrative Review.
IF 2.4 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-19 DOI: 10.23749/mdl.v115i6.15453
Zhyldyz Kurzhunbaeva, Kenesh Dzhusupov, Andrea Spinazzè, Silvia Damiana Visonà, Cholpon Sulaimanova, Omor Kasymov, Elena Belluso, Claudio Colosio

The discovery of the detrimental effects of asbestos on human health came long after its widespread use, with the first scientific evidence of asbestos-related diseases emerging in the late 19th and early 20th centuries. Despite efforts to ban its use, asbestos continues to be mined and used in Central Asia (as well as in Russia, China, and other countries). To gain a deeper understanding of the situation in Central Asia, we have conducted a systematic review of scientific literature on the use of asbestos, exposure assessment, and health consequences of asbestos exposure in this geographic area. This review encompasses studies about exposure assessments, epidemiological data, and biochemical or clinical surveys conducted in Kazakhstan, Uzbekistan, Tajikistan, Turkmenistan, and Kyrgyzstan. A total of 18 articles met the inclusion criteria, and their content is summarised in this review, which represents the first attempt to systematically examine research on asbestos and its impact on the health of workers and the general population in Central Asia countries, including literature published in Russian and English. The findings here highlighted the substantial limitations of the currently available knowledge about the impact of asbestos on health in this geographical area.

{"title":"Human Exposure to Asbestos in Central Asian Countries and Health Effects: A Narrative Review.","authors":"Zhyldyz Kurzhunbaeva, Kenesh Dzhusupov, Andrea Spinazzè, Silvia Damiana Visonà, Cholpon Sulaimanova, Omor Kasymov, Elena Belluso, Claudio Colosio","doi":"10.23749/mdl.v115i6.15453","DOIUrl":"10.23749/mdl.v115i6.15453","url":null,"abstract":"<p><p>The discovery of the detrimental effects of asbestos on human health came long after its widespread use, with the first scientific evidence of asbestos-related diseases emerging in the late 19th and early 20th centuries. Despite efforts to ban its use, asbestos continues to be mined and used in Central Asia (as well as in Russia, China, and other countries). To gain a deeper understanding of the situation in Central Asia, we have conducted a systematic review of scientific literature on the use of asbestos, exposure assessment, and health consequences of asbestos exposure in this geographic area. This review encompasses studies about exposure assessments, epidemiological data, and biochemical or clinical surveys conducted in Kazakhstan, Uzbekistan, Tajikistan, Turkmenistan, and Kyrgyzstan. A total of 18 articles met the inclusion criteria, and their content is summarised in this review, which represents the first attempt to systematically examine research on asbestos and its impact on the health of workers and the general population in Central Asia countries, including literature published in Russian and English. The findings here highlighted the substantial limitations of the currently available knowledge about the impact of asbestos on health in this geographical area.</p>","PeriodicalId":49833,"journal":{"name":"Medicina Del Lavoro","volume":"115 6","pages":"e2024042"},"PeriodicalIF":2.4,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11734637/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142856370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reflecting on Success and Looking Towards the Future.
IF 2.4 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-19 DOI: 10.23749/mdl.v115i6.16629
Antonio Mutti
{"title":"Reflecting on Success and Looking Towards the Future.","authors":"Antonio Mutti","doi":"10.23749/mdl.v115i6.16629","DOIUrl":"10.23749/mdl.v115i6.16629","url":null,"abstract":"","PeriodicalId":49833,"journal":{"name":"Medicina Del Lavoro","volume":"115 6","pages":"e2024044"},"PeriodicalIF":2.4,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11734633/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142856389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immediate Effects of Whole Body Vibration on Proprioception and Upper Extremity Reaction Speed in Young Adult Students.
IF 2.4 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-19 DOI: 10.23749/mdl.v115i6.16523
Cagtay Maden, Sedat Yiğit, Demet Karabulut, Fatma Betül Kavak, Hatice Yıldırım, Gönül Elpeze, Mehmet Göl

Background: There is limited information on the immediate effects of whole-body vibration (WBV) on the upper limb. This study aims to determine the immediate effects of WBV on reaction speed and proprioception in young adult students' upper extremities.

Methods: In total, 62 students participated in the study. WBV was applied to the participants, and its immediate effects on proprioception and upper extremity reaction speed were examined. Participants' proprioception and perception of joint position at 30-60 degrees of shoulder flexion, shoulder abduction, and elbow flexion angles were measured with absolute error degrees. Reaction rates were evaluated with the Ruler-Drop Test and the mobile application SWAY.

Results: A decrease was observed in the absolute error level of the participants' joint position perception at 30-60 elbow and shoulder position degrees, measured after immediate WBV application (p <0.05). After the RDT application, a decrease in the length of catching the target was observed (p <0.05). The SWAY test determined that they moved the smartphone in a shorter time (p <0.05). Right and left RDT scores showed that the distance to catch the ruler was significantly lower in male individuals before the application. In comparison, the distance to catch the ruler was lower after the application (right/left p<0.05).

Conclusions: The study found that applying WBV improved upper extremity proprioception perception and reaction speed in young adults. This information can guide clinicians in applying WBV to healthy individuals and those with symptoms.

{"title":"Immediate Effects of Whole Body Vibration on Proprioception and Upper Extremity Reaction Speed in Young Adult Students.","authors":"Cagtay Maden, Sedat Yiğit, Demet Karabulut, Fatma Betül Kavak, Hatice Yıldırım, Gönül Elpeze, Mehmet Göl","doi":"10.23749/mdl.v115i6.16523","DOIUrl":"10.23749/mdl.v115i6.16523","url":null,"abstract":"<p><strong>Background: </strong>There is limited information on the immediate effects of whole-body vibration (WBV) on the upper limb. This study aims to determine the immediate effects of WBV on reaction speed and proprioception in young adult students' upper extremities.</p><p><strong>Methods: </strong>In total, 62 students participated in the study. WBV was applied to the participants, and its immediate effects on proprioception and upper extremity reaction speed were examined. Participants' proprioception and perception of joint position at 30-60 degrees of shoulder flexion, shoulder abduction, and elbow flexion angles were measured with absolute error degrees. Reaction rates were evaluated with the Ruler-Drop Test and the mobile application SWAY.</p><p><strong>Results: </strong>A decrease was observed in the absolute error level of the participants' joint position perception at 30-60 elbow and shoulder position degrees, measured after immediate WBV application (p <0.05). After the RDT application, a decrease in the length of catching the target was observed (p <0.05). The SWAY test determined that they moved the smartphone in a shorter time (p <0.05). Right and left RDT scores showed that the distance to catch the ruler was significantly lower in male individuals before the application. In comparison, the distance to catch the ruler was lower after the application (right/left p<0.05).</p><p><strong>Conclusions: </strong>The study found that applying WBV improved upper extremity proprioception perception and reaction speed in young adults. This information can guide clinicians in applying WBV to healthy individuals and those with symptoms.</p>","PeriodicalId":49833,"journal":{"name":"Medicina Del Lavoro","volume":"115 6","pages":"e2024045"},"PeriodicalIF":2.4,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11734632/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142856373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Per- And Poly-Fluoroalkyl Substances (PFAS) Exposure and Risk of Breast, and Female Genital Cancers: A Systematic Review and Meta-Analysis.
IF 2.4 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-12-19 DOI: 10.23749/mdl.v115i6.16330
Monireh Sadat Seyyedsalehi, Elizabeth Maria Kappil, Sirui Zhang, Tongzhang Zheng, Paolo Boffetta

Background: PFASs, synthetic chemicals, can be encountered by humans through occupational or environmental exposure, and some reports suggest that they can disrupt endocrine and hormonal activities. In this comprehensive review and meta-analysis, we explored the connection between exposure to PFASs and the risks of breast and female genital cancers.

Methods: We systematically reviewed the literature from IARC Monographs, ATSDR documents, and PubMed (as of January 2024) for cohort, case-control, and ecological studies on PFAS exposure and breast or female genital cancers. Four reviewers independently screened studies, and data extraction included study design, patient characteristics, and effect size measures. The quality of studies was assessed using the modified version of the Newcastle-Ottawa Scale (NOS). Forest plots of relative risks (RR) were constructed for breast and female genital cancer. Meta-analyses were conducted using random-effects models, stratified analyses, dose-response assessments, and publication bias evaluation.

Results: The meta-analysis included 24 studies, comprising 10 cohort, 13 case-control, and one ecological study. The summary relative risk (RR) of breast cancer for PFOA exposure was 1.08 (95% CI = 0.97-1.20; n=21), and for PFOS was 1.00 (95% CI = 0.85-1.18; n=12). The RR for ovarian cancer and PFAS was 1.07 (95% CI = 1.04-1.09; n=12). The stratification by quality score, year of publication, and exposure source did not reveal any differences. However, analysis by geographical region (p=0.01) and study design (p=0.03) did show differences, particularly in terms of incidence. Stratified analyses of the dose-response relationship did not reveal a trend in the risk of breast cancer or female genital cancers, and no publication bias was found for either cancer type. No results were available for cervical and endometrial cancers.

Conclusion: In summary, we have found an association between PFAS exposure and ovarian cancer and a possible effect on breast cancer incidence in some specific groups. Although potential bias and confounding prevent conclusions regarding causality, these findings may hold significance for females who encounter such pollutants in their occupational or daily environments.

{"title":"Per- And Poly-Fluoroalkyl Substances (PFAS) Exposure and Risk of Breast, and Female Genital Cancers: A Systematic Review and Meta-Analysis.","authors":"Monireh Sadat Seyyedsalehi, Elizabeth Maria Kappil, Sirui Zhang, Tongzhang Zheng, Paolo Boffetta","doi":"10.23749/mdl.v115i6.16330","DOIUrl":"10.23749/mdl.v115i6.16330","url":null,"abstract":"<p><strong>Background: </strong>PFASs, synthetic chemicals, can be encountered by humans through occupational or environmental exposure, and some reports suggest that they can disrupt endocrine and hormonal activities. In this comprehensive review and meta-analysis, we explored the connection between exposure to PFASs and the risks of breast and female genital cancers.</p><p><strong>Methods: </strong>We systematically reviewed the literature from IARC Monographs, ATSDR documents, and PubMed (as of January 2024) for cohort, case-control, and ecological studies on PFAS exposure and breast or female genital cancers. Four reviewers independently screened studies, and data extraction included study design, patient characteristics, and effect size measures. The quality of studies was assessed using the modified version of the Newcastle-Ottawa Scale (NOS). Forest plots of relative risks (RR) were constructed for breast and female genital cancer. Meta-analyses were conducted using random-effects models, stratified analyses, dose-response assessments, and publication bias evaluation.</p><p><strong>Results: </strong>The meta-analysis included 24 studies, comprising 10 cohort, 13 case-control, and one ecological study. The summary relative risk (RR) of breast cancer for PFOA exposure was 1.08 (95% CI = 0.97-1.20; n=21), and for PFOS was 1.00 (95% CI = 0.85-1.18; n=12). The RR for ovarian cancer and PFAS was 1.07 (95% CI = 1.04-1.09; n=12). The stratification by quality score, year of publication, and exposure source did not reveal any differences. However, analysis by geographical region (p=0.01) and study design (p=0.03) did show differences, particularly in terms of incidence. Stratified analyses of the dose-response relationship did not reveal a trend in the risk of breast cancer or female genital cancers, and no publication bias was found for either cancer type. No results were available for cervical and endometrial cancers.</p><p><strong>Conclusion: </strong>In summary, we have found an association between PFAS exposure and ovarian cancer and a possible effect on breast cancer incidence in some specific groups. Although potential bias and confounding prevent conclusions regarding causality, these findings may hold significance for females who encounter such pollutants in their occupational or daily environments.</p>","PeriodicalId":49833,"journal":{"name":"Medicina Del Lavoro","volume":"115 6","pages":"e2024043"},"PeriodicalIF":2.4,"publicationDate":"2024-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11734636/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142856386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Occupational Exposure to Benzene and Risk of Breast Cancer: Systematic Review and Meta-Analysis. 职业暴露于苯与乳腺癌风险:系统回顾与元分析》。
IF 2.4 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-24 DOI: 10.23749/mdl.v115i5.16306
Monireh Sadat Seyyedsalehi, Vincent Destefano, Darshi Shah, Veer Shah, Mattia Bonetti, Paolo Boffetta

Introduction: Benzene is a recognized carcinogen; however, its association with breast cancer is not well established. Hence, a meta-analysis of cohort and case-control studies was performed to determine the association between occupational benzene exposure and the risk of breast cancer.

Methods: A systematic literature review identified 7573 publications from which 23 cohort and case-control studies were retained and evaluated using meta-analyses (fixed effects model). PRISMA guidelines were followed. Our protocol was registered in the PROSPERO database (Registration No. CRD42022379720). Study quality was assessed using a modified Newcastle-Ottawa scale (NOS).

Results: The summary relative risk (RR) for ever-benzene exposure was 1.08 (95% CI=1.03-1.14, I2=38.6%, n=23 risk estimates); corresponding RR for cancer incidence and mortality were 1.08 (95% CI=1.02-1.14, I2=56.1%, n=16) and 1.10 (95% CI=0.87-1.37, I2<0.001%, n=10). However, heterogeneity was detected for sex (p-het=0.002), publication year (p-het<0.001), study design (p-het<0.001), study quality (p-het<0.001), and industry of employment (p-het=0.03). The RR for high level of exposure showed positive association with breast cancer 1.35 (95% CI=1.06-1.72, I2 =<0.001%, n=3) and (P-het=0.64). Publication bias was detected (p=0.03).

Conclusions: The results of our meta-analysis indicate a positive association between occupational benzene exposure and an increased risk of breast cancer, particularly when exposed to higher levels of benzene. However, bias and confounding could not be excluded.

简介:苯是一种公认的致癌物质,但其与乳腺癌的关系尚未得到充分证实。因此,我们对队列研究和病例对照研究进行了荟萃分析,以确定职业苯暴露与乳腺癌风险之间的关系:方法:通过系统性文献综述确定了 7573 篇文献,从中保留了 23 项队列研究和病例对照研究,并使用荟萃分析(固定效应模型)对其进行了评估。研究遵循了 PRISMA 指南。我们的研究方案已在 PROSPERO 数据库中注册(注册号:CRD42022379720)。研究质量采用修改后的纽卡斯尔-渥太华量表(NOS)进行评估:曾经接触苯的总相对风险 (RR) 为 1.08(95% CI=1.03-1.14,I2=38.6%,n=23 个风险估计值);癌症发病率和死亡率的相应 RR 分别为 1.08(95% CI=1.02-1.14,I2=56.1%,n=16)和 1.10(95% CI=0.87-1.37,I2C):我们的荟萃分析结果表明,职业性苯暴露与乳腺癌风险增加之间存在正相关,尤其是当暴露于较高水平的苯时。但是,无法排除偏倚和混杂因素。
{"title":"Occupational Exposure to Benzene and Risk of Breast Cancer: Systematic Review and Meta-Analysis.","authors":"Monireh Sadat Seyyedsalehi, Vincent Destefano, Darshi Shah, Veer Shah, Mattia Bonetti, Paolo Boffetta","doi":"10.23749/mdl.v115i5.16306","DOIUrl":"10.23749/mdl.v115i5.16306","url":null,"abstract":"<p><strong>Introduction: </strong>Benzene is a recognized carcinogen; however, its association with breast cancer is not well established. Hence, a meta-analysis of cohort and case-control studies was performed to determine the association between occupational benzene exposure and the risk of breast cancer.</p><p><strong>Methods: </strong>A systematic literature review identified 7573 publications from which 23 cohort and case-control studies were retained and evaluated using meta-analyses (fixed effects model). PRISMA guidelines were followed. Our protocol was registered in the PROSPERO database (Registration No. CRD42022379720). Study quality was assessed using a modified Newcastle-Ottawa scale (NOS).</p><p><strong>Results: </strong>The summary relative risk (RR) for ever-benzene exposure was 1.08 (95% CI=1.03-1.14, I2=38.6%, n=23 risk estimates); corresponding RR for cancer incidence and mortality were 1.08 (95% CI=1.02-1.14, I2=56.1%, n=16) and 1.10 (95% CI=0.87-1.37, I2<0.001%, n=10). However, heterogeneity was detected for sex (p-het=0.002), publication year (p-het<0.001), study design (p-het<0.001), study quality (p-het<0.001), and industry of employment (p-het=0.03). The RR for high level of exposure showed positive association with breast cancer 1.35 (95% CI=1.06-1.72, I2 =<0.001%, n=3) and (P-het=0.64). Publication bias was detected (p=0.03).</p><p><strong>Conclusions: </strong>The results of our meta-analysis indicate a positive association between occupational benzene exposure and an increased risk of breast cancer, particularly when exposed to higher levels of benzene. However, bias and confounding could not be excluded.</p>","PeriodicalId":49833,"journal":{"name":"Medicina Del Lavoro","volume":"115 5","pages":"e2024034"},"PeriodicalIF":2.4,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11562665/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Occupational Safety and Health of Riders Working for Digital Food Delivery Platforms in the City of Milan, Italy. 意大利米兰市数字送餐平台骑手的职业安全与健康。
IF 2.4 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-24 DOI: 10.23749/mdl.v115i5.16278
Luca Boniardi, Laura Campo, Sofia Prudenzi, Luciano Fasano, Paolo Natale, Dario Consonni, Michele Carugno, Angela Cecilia Pesatori, Silvia Fustinoni

Background: The rapid growth of the digital economy has transformed various labor markets, including the food sector. The transient nature and the peculiar work environments of food delivery workers raise concerns about occupational safety and health (OSH). This study aims to better understand these issues by conducting a comprehensive exploratory survey on OSH among food delivery riders in Milan, Italy.

Methods:  The study employed structured interviews based on a validated questionnaire developed through a literature review, expert interviews, and input from riders and health and safety professionals. The survey was performed from July to November 2022 by interviewing riders at their main gathering points.

Results: We interviewed 240 riders, 97% males, 81% less than 35 years old, and 83% with extra-European origin. Delivery was performed mainly by traditional bicycles (40%) and e-bikes (46%), with 44% working seven days per week and 23% working more than 8 hours daily. Road accidents were reported by 39% of riders, influenced by type of vehicle, fatigue, and number of daily deliveries. Physical and verbal assaults (12% and 28%, respectively) were reported, as well as health-related issues, particularly musculoskeletal disorders.

Conclusions: The findings underscore food delivery riders' complex challenges, emphasizing the need for targeted interventions. The study calls for collaborative efforts between policymakers, employers, OSH professionals, and stakeholders to enhance OSH standards and promote decent working conditions, aligning with the 2030 Agenda for Sustainable Development.

背景:数字经济的快速发展改变了包括食品行业在内的各种劳动力市场。送餐员的流动性和特殊的工作环境引起了人们对职业安全与健康(OSH)的关注。本研究旨在通过对意大利米兰食品外卖骑手的职业安全和健康进行全面的探索性调查,更好地了解这些问题: 研究采用了结构化访谈的方法,该方法基于通过文献综述、专家访谈以及骑手和健康与安全专业人士的意见而制定的有效问卷。调查于 2022 年 7 月至 11 月在骑手的主要聚集点进行:我们采访了 240 名骑手,其中 97% 为男性,81% 年龄在 35 岁以下,83% 来自欧洲以外地区。主要使用传统自行车(40%)和电动自行车(46%)送货,44%的人每周工作七天,23%的人每天工作超过 8 小时。39%的骑行者报告了交通事故,影响因素包括车辆类型、疲劳程度和每日送货次数。此外,还报告了人身攻击和语言攻击(分别占 12% 和 28%)以及与健康有关的问题,尤其是肌肉骨骼疾病:研究结果凸显了送餐员面临的复杂挑战,强调了采取有针对性干预措施的必要性。这项研究呼吁决策者、雇主、职业安全和健康专业人员以及利益相关者通力合作,提高职业安全和健康标准,促进体面的工作条件,与《2030 年可持续发展议程》保持一致。
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引用次数: 0
Factor Structure, Psychometric Properties, and Measurement Invariance of the Pandemic Experiences and Perceptions Scale Among Italian Hospital Workers. 意大利医院工作人员大流行病经历和感知量表的因子结构、心理测量特性和测量不变性。
IF 2.4 4区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-10-24 DOI: 10.23749/mdl.v115i5.16053
Igor Portoghese, Maura Galletta, Michael P Leiter, Ilenia Piras, Luigi Isaia Lecca, Monica Puligheddu, Marcello Campagna

Background: The COVID-19 pandemic represented substantial risks to hospital workers' physical and mental health. The availability of validated measures on the impact of the pandemic on workplaces is crucial for developing data-driven interventions. The primary purpose of our study was to translate it into Italian and assess factor structure, psychometric properties, and measurement invariance of the Pandemic Experiences and Perceptions Scale (PEPS).

Methods: The survey was completed by 766 workers from an Italian hospital. We examined the internal structure of the PEPS using confirmatory factor analyses (CFA) and exploratory structural equation modeling (ESEM) techniques and testing the invariance for clinical vs. nonclinical workers.

Results: The six-factor ESEM solution showed an excellent fit to the data (CFI=0.956, TLI=0.932, RMSEA=0.050), supporting the superiority of the ESEM solution. The factorial invariance of the PEPS across occupational roles (clinical vs. nonclinical hospital workers) was supported, and the ESEM-based McDonald's omega was good for all factors.

Conclusions: The results from this study provided evidence for the factorial validity, reliability, and measurement invariance across occupational roles of the Italian version of the PEPS. Thus, the Italian version of the PEPS is a reliable and valid tool for assessing pandemic experiences and perceptions among Italian workers.

背景:COVID-19 大流行给医院工作人员的身心健康带来了巨大风险。提供有关大流行病对工作场所影响的有效测量方法对于制定数据驱动的干预措施至关重要。我们研究的主要目的是将该量表翻译成意大利文,并评估大流行病经历与感知量表(PEPS)的因子结构、心理测量特性和测量不变性:一家意大利医院的 766 名员工完成了调查。我们使用确证因子分析(CFA)和探索性结构方程建模(ESEM)技术研究了 PEPS 的内部结构,并测试了临床与非临床工作人员的不变性:六因素 ESEM 方案与数据的拟合度非常好(CFI=0.956、TLI=0.932、RMSEA=0.050),证明了 ESEM 方案的优越性。PEPS在不同职业角色(临床与非临床医院工作人员)之间的因子不变性得到了支持,基于ESEM的麦当劳欧米茄对所有因子的拟合效果良好:本研究的结果为意大利版 PEPS 的因子效度、可靠性和不同职业角色的测量不变性提供了证据。因此,意大利语版 PEPS 是评估意大利工人对大流行病的体验和看法的可靠而有效的工具。
{"title":"Factor Structure, Psychometric Properties, and Measurement Invariance of the Pandemic Experiences and Perceptions Scale Among Italian Hospital Workers.","authors":"Igor Portoghese, Maura Galletta, Michael P Leiter, Ilenia Piras, Luigi Isaia Lecca, Monica Puligheddu, Marcello Campagna","doi":"10.23749/mdl.v115i5.16053","DOIUrl":"10.23749/mdl.v115i5.16053","url":null,"abstract":"<p><strong>Background: </strong>The COVID-19 pandemic represented substantial risks to hospital workers' physical and mental health. The availability of validated measures on the impact of the pandemic on workplaces is crucial for developing data-driven interventions. The primary purpose of our study was to translate it into Italian and assess factor structure, psychometric properties, and measurement invariance of the Pandemic Experiences and Perceptions Scale (PEPS).</p><p><strong>Methods: </strong>The survey was completed by 766 workers from an Italian hospital. We examined the internal structure of the PEPS using confirmatory factor analyses (CFA) and exploratory structural equation modeling (ESEM) techniques and testing the invariance for clinical vs. nonclinical workers.</p><p><strong>Results: </strong>The six-factor ESEM solution showed an excellent fit to the data (CFI=0.956, TLI=0.932, RMSEA=0.050), supporting the superiority of the ESEM solution. The factorial invariance of the PEPS across occupational roles (clinical vs. nonclinical hospital workers) was supported, and the ESEM-based McDonald's omega was good for all factors.</p><p><strong>Conclusions: </strong>The results from this study provided evidence for the factorial validity, reliability, and measurement invariance across occupational roles of the Italian version of the PEPS. Thus, the Italian version of the PEPS is a reliable and valid tool for assessing pandemic experiences and perceptions among Italian workers.</p>","PeriodicalId":49833,"journal":{"name":"Medicina Del Lavoro","volume":"115 5","pages":"e2024033"},"PeriodicalIF":2.4,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11562670/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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