Pub Date : 2024-06-21DOI: 10.23749/mdl.v115i3.15931
Rui André Mendes Ribeiro, Vanessa Teófilo, Salomé Moreira, Paulo Pinho, Pedro Norton, Teresa Pereira
Contact dermatitis is a common cutaneous inflammatory condition, triggered by exposure to irritant substances or allergens. Nickel is the most prevalent allergen, a metal widely used in accessories, furniture, office materials, food and in industry, with multiple exposure pathways, making it difficult to assess which exposure is causing allergic dermatitis. Here, we report a case of an administrative worker with chronic hand eczema, limited to the radial metacarpophalangeal region of the left hand, caused by occupational exposure to nickel, confirmed by nickel deposition test on the hand and a positive test with a metallic stapler used at her workplace.
{"title":"Managing Allergic Nickel Dermatitis in Occupational Settings: A Case Report.","authors":"Rui André Mendes Ribeiro, Vanessa Teófilo, Salomé Moreira, Paulo Pinho, Pedro Norton, Teresa Pereira","doi":"10.23749/mdl.v115i3.15931","DOIUrl":"10.23749/mdl.v115i3.15931","url":null,"abstract":"<p><p>Contact dermatitis is a common cutaneous inflammatory condition, triggered by exposure to irritant substances or allergens. Nickel is the most prevalent allergen, a metal widely used in accessories, furniture, office materials, food and in industry, with multiple exposure pathways, making it difficult to assess which exposure is causing allergic dermatitis. Here, we report a case of an administrative worker with chronic hand eczema, limited to the radial metacarpophalangeal region of the left hand, caused by occupational exposure to nickel, confirmed by nickel deposition test on the hand and a positive test with a metallic stapler used at her workplace.</p>","PeriodicalId":49833,"journal":{"name":"Medicina Del Lavoro","volume":"115 3","pages":"e2024021"},"PeriodicalIF":2.4,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11223567/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141460380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-21DOI: 10.23749/mdl.v115i3.15863
Laura Campo, Luca Boniardi, Luca Olgiati, Elisa Polledri, Rosa Mercadante, Silvia Fustinoni
Background: In the regeneration of waste oil, a strategical technological process for the European Union circular economy action plan, exhausted oils are regenerated to produce high performing oil bases. Aim of this work was to assess the exposure to benzene in plant workers during ordinary activities.
Methods: 59 workers, potentially exposed to benzene, and 9 administrative workers from an Italian plant were monitored for the whole work shift with personal air samplers; urinary benzene (BEN-U) and S-phenyl mercapturic acid (SPMA) were measured by mass spectrometry methods in end-shift urine samples. Different job tasks were identified among workers.
Results: Median (minimum-maximum) airborne exposures to benzene were <0.9 (<0.9-6.3) and <0.9 (<0.9-0.9) µg/m3, BEN-U and SPMA levels were 0.094 (<0.015-3.095) µg/L and 0.15 (<0.10-9.67) µg/g crt and 0.086 (0.034-0.712) µg/L and <0.10 (<0.10-3.19) µg/g creatinine in workers and administrative workers, respectively. No differences were found among job tasks and between workers and administrative workers, while higher levels were found in smokers than in non-smokers. For all job tasks, the exposure to benzene was always below occupational limit values.
Conclusions: This study has investigated for the first time the exposure to benzene of workers employed in the re-refining of exhaust oil. The results showed that normal production activities in regenerating used oils do not pose a risk of exposure to benzene in workers.
{"title":"Benzene Exposure in Workers From a Waste Oil Regeneration Plant During Ordinary Activities by Air and Biological Monitoring.","authors":"Laura Campo, Luca Boniardi, Luca Olgiati, Elisa Polledri, Rosa Mercadante, Silvia Fustinoni","doi":"10.23749/mdl.v115i3.15863","DOIUrl":"10.23749/mdl.v115i3.15863","url":null,"abstract":"<p><strong>Background: </strong>In the regeneration of waste oil, a strategical technological process for the European Union circular economy action plan, exhausted oils are regenerated to produce high performing oil bases. Aim of this work was to assess the exposure to benzene in plant workers during ordinary activities.</p><p><strong>Methods: </strong>59 workers, potentially exposed to benzene, and 9 administrative workers from an Italian plant were monitored for the whole work shift with personal air samplers; urinary benzene (BEN-U) and S-phenyl mercapturic acid (SPMA) were measured by mass spectrometry methods in end-shift urine samples. Different job tasks were identified among workers.</p><p><strong>Results: </strong>Median (minimum-maximum) airborne exposures to benzene were <0.9 (<0.9-6.3) and <0.9 (<0.9-0.9) µg/m3, BEN-U and SPMA levels were 0.094 (<0.015-3.095) µg/L and 0.15 (<0.10-9.67) µg/g crt and 0.086 (0.034-0.712) µg/L and <0.10 (<0.10-3.19) µg/g creatinine in workers and administrative workers, respectively. No differences were found among job tasks and between workers and administrative workers, while higher levels were found in smokers than in non-smokers. For all job tasks, the exposure to benzene was always below occupational limit values.</p><p><strong>Conclusions: </strong>This study has investigated for the first time the exposure to benzene of workers employed in the re-refining of exhaust oil. The results showed that normal production activities in regenerating used oils do not pose a risk of exposure to benzene in workers.</p>","PeriodicalId":49833,"journal":{"name":"Medicina Del Lavoro","volume":"115 3","pages":"e2024017"},"PeriodicalIF":2.4,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11223561/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141460377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-21DOI: 10.23749/mdl.v115i3.15265
Angela Gomez-Dominguez, Pedro Ferrer-Rosende, Laura Esteve-Matali, Clara Llorens-Serrano, Sergio Salas-Nicás, Albert Navarro-Giné
Background: In recent years, substantial changes have occurred in the work organization and arrangements. One of the main ones has been the popularization of teleworking among non-manual workers. This paper aims to assess the exposure of psychosocial risks among non-manual Spanish wage-earners, depending on the working modality (mainly telework, combining teleworking with onsite work, or onsite work).
Methods: Based on an online survey conducted between April and May 2021, a cross-sectional study was carried out among n=11,519 members of a trade union where Psychosocial Risks (PSR) were measured through COPSOQ Questionnaire Scales. All analyses were performed stratifying by sex.
Results: Women who combine telework and face-to-face work (aPR: 1.21; 95%CI 1.07-1.37) and men who mainly telework (aPR: 1.26; 95%CI 1.11-1.43) and that combine (aPR: 1.27; 95%CI 1.11-1.45) are more exposed to quantitative demands than men and women who do not telework. On the other hand, women who telework, either entirely (aPR: 0.89; 95%CI 0.82-0.97) or combining (aPR: 0.89; 95%CI 0.81-0.98), are less exposed to emotional demands than women who do not telework, and the same occurs among men who mainly telework (aPR: 0.84; 95%CI 0.76-0.92). Telework and horizontal or vertical social support are not associated, except for supervisor support among males, nor with work-life conflict.
Conclusions: Except for quantitative demands, employees who combine telework and face-to-face work are less exposed to psychosocial risks than those who mainly telework or work face-to-face only. More studies with a gender and class perspective are needed in this area.
{"title":"Comparing Exposure to Psychosocial Risks: Face-to-Face Work vs. Telework.","authors":"Angela Gomez-Dominguez, Pedro Ferrer-Rosende, Laura Esteve-Matali, Clara Llorens-Serrano, Sergio Salas-Nicás, Albert Navarro-Giné","doi":"10.23749/mdl.v115i3.15265","DOIUrl":"10.23749/mdl.v115i3.15265","url":null,"abstract":"<p><strong>Background: </strong>In recent years, substantial changes have occurred in the work organization and arrangements. One of the main ones has been the popularization of teleworking among non-manual workers. This paper aims to assess the exposure of psychosocial risks among non-manual Spanish wage-earners, depending on the working modality (mainly telework, combining teleworking with onsite work, or onsite work).</p><p><strong>Methods: </strong>Based on an online survey conducted between April and May 2021, a cross-sectional study was carried out among n=11,519 members of a trade union where Psychosocial Risks (PSR) were measured through COPSOQ Questionnaire Scales. All analyses were performed stratifying by sex.</p><p><strong>Results: </strong>Women who combine telework and face-to-face work (aPR: 1.21; 95%CI 1.07-1.37) and men who mainly telework (aPR: 1.26; 95%CI 1.11-1.43) and that combine (aPR: 1.27; 95%CI 1.11-1.45) are more exposed to quantitative demands than men and women who do not telework. On the other hand, women who telework, either entirely (aPR: 0.89; 95%CI 0.82-0.97) or combining (aPR: 0.89; 95%CI 0.81-0.98), are less exposed to emotional demands than women who do not telework, and the same occurs among men who mainly telework (aPR: 0.84; 95%CI 0.76-0.92). Telework and horizontal or vertical social support are not associated, except for supervisor support among males, nor with work-life conflict.</p><p><strong>Conclusions: </strong>Except for quantitative demands, employees who combine telework and face-to-face work are less exposed to psychosocial risks than those who mainly telework or work face-to-face only. More studies with a gender and class perspective are needed in this area.</p>","PeriodicalId":49833,"journal":{"name":"Medicina Del Lavoro","volume":"115 3","pages":"e2024020"},"PeriodicalIF":2.4,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11223562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141460378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-21DOI: 10.23749/mdl.v115i3.16038
Bruna Maria Rondinone, Giuliana Buresti, Sergio Iavicoli, Paolo Durando, Mario Alberto Battaglia, Guglielmo Dini, Alfredo Montecucco, Alborz Rahmani, Nicoletta Debarbieri, Paolo Bandiera, Michela Ponzio, Tommaso Manacorda, Elena Pignattelli, Matilde Inglese, Benedetta Persechino
Background: This study, conducted on a sample of Italian occupational physicians (OPs), aimed to gather data regarding professional activity and their needs in managing workers with multiple sclerosis.
Methods: A convenience sample of OPs recruited by e-mail invitation to the list of Italian Society of Occupational Medicine members was considered. A total of 220 OPs participated between July and October 2022. An ad hoc questionnaire was developed based on previous survey experiences. It investigated, among others, the characteristics of OP respondents, the evaluation of fitness for work issues, and the OP training and updating needs on multiple sclerosis and work.
Results: Ninety-one percent of OPs had to assess the fitness for work of workers with multiple sclerosis during their activity. Sixty-four percent experienced particular difficulties in issuing a fitness for work judgment. Regarding the level of knowledge on multiple sclerosis, 54% judged it sufficient. The "Assessment of fitness for work for the specific task" and the "Role of the OPs in identifying reasonable accommodations" were the most interesting training topics regarding MS management in work contexts chosen by the respondents.
Conclusions: The interest in the work inclusion and job retention of people with disability, particularly the aspects linked to the Identification and implementation of reasonable accommodations, will require integration with the occupational safety and health protection system and will undoubtedly impact the OP's activities.
{"title":"Occupational Physicians' Management of Workers With Multiple Sclerosis in Italy: Results From a Survey.","authors":"Bruna Maria Rondinone, Giuliana Buresti, Sergio Iavicoli, Paolo Durando, Mario Alberto Battaglia, Guglielmo Dini, Alfredo Montecucco, Alborz Rahmani, Nicoletta Debarbieri, Paolo Bandiera, Michela Ponzio, Tommaso Manacorda, Elena Pignattelli, Matilde Inglese, Benedetta Persechino","doi":"10.23749/mdl.v115i3.16038","DOIUrl":"10.23749/mdl.v115i3.16038","url":null,"abstract":"<p><strong>Background: </strong>This study, conducted on a sample of Italian occupational physicians (OPs), aimed to gather data regarding professional activity and their needs in managing workers with multiple sclerosis.</p><p><strong>Methods: </strong>A convenience sample of OPs recruited by e-mail invitation to the list of Italian Society of Occupational Medicine members was considered. A total of 220 OPs participated between July and October 2022. An ad hoc questionnaire was developed based on previous survey experiences. It investigated, among others, the characteristics of OP respondents, the evaluation of fitness for work issues, and the OP training and updating needs on multiple sclerosis and work.</p><p><strong>Results: </strong>Ninety-one percent of OPs had to assess the fitness for work of workers with multiple sclerosis during their activity. Sixty-four percent experienced particular difficulties in issuing a fitness for work judgment. Regarding the level of knowledge on multiple sclerosis, 54% judged it sufficient. The \"Assessment of fitness for work for the specific task\" and the \"Role of the OPs in identifying reasonable accommodations\" were the most interesting training topics regarding MS management in work contexts chosen by the respondents.</p><p><strong>Conclusions: </strong>The interest in the work inclusion and job retention of people with disability, particularly the aspects linked to the Identification and implementation of reasonable accommodations, will require integration with the occupational safety and health protection system and will undoubtedly impact the OP's activities.</p>","PeriodicalId":49833,"journal":{"name":"Medicina Del Lavoro","volume":"115 3","pages":"e2024022"},"PeriodicalIF":2.4,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11223566/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141460381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-21DOI: 10.23749/mdl.v115i3.15947
Michela Ponzio, Elena Pignattelli, Anna Verri, Erica Grange, Benedetta Persechino, Bruno Kusznir Vitturi, Paolo Bandiera, Tommaso Manacorda, Matilde Inglese, Paolo Durando, Mario Alberto Battaglia
Background: Multiple sclerosis (MS), because of its early age at onset, greatly impacts the working lives of those affected by it in ways linked to different factors, both professional and personal. It has been observed that only a small percentage (20-40%) of workers with MS retain their jobs after the diagnosis. When identifying factors determining job retention or loss in this setting, it is essential to consider the direct perspectives of people with MS (PwMS).
Methods: A qualitative study, based on the conduction of two focus groups, was conducted to explore the personal experiences of PwMS who work.
Results: The results show that there are numerous factors, both positive and negative, that can influence these people's ability to retain their jobs. The climate established in the workplace and the relationship between workers with MS and their colleagues were fundamentally important aspects, as was knowledge of the disease at the level of public opinion.
Conclusions: Managing work is a complex undertaking for people with a disabling condition like MS. There needs to be greater awareness of the employment rights of PwMS. Improving these knowledge-based aspects could undoubtedly improve the quality of the working lives of PwM.
{"title":"Job Retention by People With Disabilities: A Qualitative Study of the Perspectives of People With Multiple Sclerosis.","authors":"Michela Ponzio, Elena Pignattelli, Anna Verri, Erica Grange, Benedetta Persechino, Bruno Kusznir Vitturi, Paolo Bandiera, Tommaso Manacorda, Matilde Inglese, Paolo Durando, Mario Alberto Battaglia","doi":"10.23749/mdl.v115i3.15947","DOIUrl":"10.23749/mdl.v115i3.15947","url":null,"abstract":"<p><strong>Background: </strong>Multiple sclerosis (MS), because of its early age at onset, greatly impacts the working lives of those affected by it in ways linked to different factors, both professional and personal. It has been observed that only a small percentage (20-40%) of workers with MS retain their jobs after the diagnosis. When identifying factors determining job retention or loss in this setting, it is essential to consider the direct perspectives of people with MS (PwMS).</p><p><strong>Methods: </strong>A qualitative study, based on the conduction of two focus groups, was conducted to explore the personal experiences of PwMS who work.</p><p><strong>Results: </strong>The results show that there are numerous factors, both positive and negative, that can influence these people's ability to retain their jobs. The climate established in the workplace and the relationship between workers with MS and their colleagues were fundamentally important aspects, as was knowledge of the disease at the level of public opinion.</p><p><strong>Conclusions: </strong>Managing work is a complex undertaking for people with a disabling condition like MS. There needs to be greater awareness of the employment rights of PwMS. Improving these knowledge-based aspects could undoubtedly improve the quality of the working lives of PwM.</p>","PeriodicalId":49833,"journal":{"name":"Medicina Del Lavoro","volume":"115 3","pages":"e2024018"},"PeriodicalIF":2.4,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11223563/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141460379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-21DOI: 10.23749/mdl.v115i3.16072
Yves Roquelaure, Julie Bodin, Florence Cros, Alexis Descatha, Marc Fadel
Work-related musculoskeletal disorders (WRMSD) pose a significant occupational health challenge in Europe. The digitization of the economy substantially reshaped the nature and organization of work. The proliferation of hybrid working, characterized by a combination of office-based and remote work, has been accelerated by the COVID-19 pandemic. This review covers hybrid forms of work, their impact on WRMSDs, and the potential implications for WRMSD compensation. Approximately 30-40% of the European workforce could potentially transition to hybrid forms of work. Hybrid work arrangements can result in prolonged static postures of the trunk, neck, and upper limbs without adequate breaks, thereby increasing the risk of neck and lower back pain. As teleworking and hybrid working become more prevalent, an increase in non-specific WRMSDs is anticipated among the working population. In many countries, claims for WRMSDs necessitate a formal diagnosis by a healthcare professional. However, cases of non-specific WRMSDs, such as cervicalgia or chronic shoulder pain, - commonly observed in sedentary workers engaged in predominantly low-intensity, prolonged static work amid visually and cognitively demanding tasks - often do not meet the criteria for compensation as occupational diseases. The compensation system and/or the criteria for compensation must be adapted to accommodate the rise of telework, necessitating evolving criteria for compensation that address both medical and risk exposure considerations.
{"title":"The Digital Economy and Hybrid Work Call for a Review of Compensation Criteria for Musculoskeletal Disorders.","authors":"Yves Roquelaure, Julie Bodin, Florence Cros, Alexis Descatha, Marc Fadel","doi":"10.23749/mdl.v115i3.16072","DOIUrl":"10.23749/mdl.v115i3.16072","url":null,"abstract":"<p><p>Work-related musculoskeletal disorders (WRMSD) pose a significant occupational health challenge in Europe. The digitization of the economy substantially reshaped the nature and organization of work. The proliferation of hybrid working, characterized by a combination of office-based and remote work, has been accelerated by the COVID-19 pandemic. This review covers hybrid forms of work, their impact on WRMSDs, and the potential implications for WRMSD compensation. Approximately 30-40% of the European workforce could potentially transition to hybrid forms of work. Hybrid work arrangements can result in prolonged static postures of the trunk, neck, and upper limbs without adequate breaks, thereby increasing the risk of neck and lower back pain. As teleworking and hybrid working become more prevalent, an increase in non-specific WRMSDs is anticipated among the working population. In many countries, claims for WRMSDs necessitate a formal diagnosis by a healthcare professional. However, cases of non-specific WRMSDs, such as cervicalgia or chronic shoulder pain, - commonly observed in sedentary workers engaged in predominantly low-intensity, prolonged static work amid visually and cognitively demanding tasks - often do not meet the criteria for compensation as occupational diseases. The compensation system and/or the criteria for compensation must be adapted to accommodate the rise of telework, necessitating evolving criteria for compensation that address both medical and risk exposure considerations.</p>","PeriodicalId":49833,"journal":{"name":"Medicina Del Lavoro","volume":"115 3","pages":"e2024019"},"PeriodicalIF":2.4,"publicationDate":"2024-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11223565/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141460383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-24DOI: 10.23749/mdl.v115i2.15835
Mohamed El-Helaly
This paper discusses the impact of artificial intelligence (AI) on occupational health and safety. Although the integration of AI into the field of occupational health and safety is still in its early stages, it has numerous applications in the workplace. Some of these applications offer numerous benefits for the health and safety of workers, such as continuous monitoring of workers' health and safety and the workplace environment through wearable devices and sensors. However, AI might have negative impacts in the workplace, such as ethical worries and data privacy concerns. To maximize the benefits and minimize the drawbacks of AI in the workplace, certain measures should be applied, such as training for both employers and employees and setting policies and guidelines regulating the integration of AI in the workplace.
{"title":"Artificial Intelligence and Occupational Health and Safety, Benefits and Drawbacks.","authors":"Mohamed El-Helaly","doi":"10.23749/mdl.v115i2.15835","DOIUrl":"10.23749/mdl.v115i2.15835","url":null,"abstract":"<p><p>This paper discusses the impact of artificial intelligence (AI) on occupational health and safety. Although the integration of AI into the field of occupational health and safety is still in its early stages, it has numerous applications in the workplace. Some of these applications offer numerous benefits for the health and safety of workers, such as continuous monitoring of workers' health and safety and the workplace environment through wearable devices and sensors. However, AI might have negative impacts in the workplace, such as ethical worries and data privacy concerns. To maximize the benefits and minimize the drawbacks of AI in the workplace, certain measures should be applied, such as training for both employers and employees and setting policies and guidelines regulating the integration of AI in the workplace.</p>","PeriodicalId":49833,"journal":{"name":"Medicina Del Lavoro","volume":"115 2","pages":"e2024014"},"PeriodicalIF":2.7,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11181216/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140853505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-24DOI: 10.23749/mdl.v115i2.15609
Francesca Borghi, Carolina Zellino, Arianna Zago, Giovanni De Vito, Rocco Loris Del Vecchio, Andrea Cattaneo, Andrea Spinazzè, Domenico Maria Cavallo
Several antiblastic drugs (ADs) are classified as carcinogenic, mutagenic, and/or toxic for reproduction. Despite established guidelines and safe handling technologies, ADs contamination of the work environments could occur in healthcare settings, leading to potential exposure of healthcare staff. This systematic review aims to investigate the main techniques and practices for assessing ADs occupational exposure in healthcare settings. The reviewed studies unveil that workplace contamination by ADs appears to be a still-topical problem in healthcare settings. These issues are linked to difficulties in guaranteeing: (i) the adherence to standardized protocols when dealing with ADs, (ii) the effective use of personal protective equipment by operators involved in the administration or management of ADs, (iii) a comprehensive training of the healthcare personnel, and (iv) a thorough health surveillance of exposed workers. A "multi-parametric" approach emerges as a desirable strategy for exposure assessment. In parallel, exposure assessment should coincide with the introduction of novel technologies aimed at minimizing exposure (i.e., risk management). Assessment must consider various departments and health operators susceptible to ADs contamination, with a focus extended beyond worst-case scenarios, also considering activities like surface cleaning and logistical tasks related to ADs management. A comprehensive approach in ADs risk assessment enables the evaluation of distinct substance behaviors and subsequent exposure routes, affording a more holistic understanding of potential risks.
{"title":"Exposure Assessment and Monitoring of Antiblastic Drugs Preparation in Health Care Settings: A Systematic Review.","authors":"Francesca Borghi, Carolina Zellino, Arianna Zago, Giovanni De Vito, Rocco Loris Del Vecchio, Andrea Cattaneo, Andrea Spinazzè, Domenico Maria Cavallo","doi":"10.23749/mdl.v115i2.15609","DOIUrl":"10.23749/mdl.v115i2.15609","url":null,"abstract":"<p><p>Several antiblastic drugs (ADs) are classified as carcinogenic, mutagenic, and/or toxic for reproduction. Despite established guidelines and safe handling technologies, ADs contamination of the work environments could occur in healthcare settings, leading to potential exposure of healthcare staff. This systematic review aims to investigate the main techniques and practices for assessing ADs occupational exposure in healthcare settings. The reviewed studies unveil that workplace contamination by ADs appears to be a still-topical problem in healthcare settings. These issues are linked to difficulties in guaranteeing: (i) the adherence to standardized protocols when dealing with ADs, (ii) the effective use of personal protective equipment by operators involved in the administration or management of ADs, (iii) a comprehensive training of the healthcare personnel, and (iv) a thorough health surveillance of exposed workers. A \"multi-parametric\" approach emerges as a desirable strategy for exposure assessment. In parallel, exposure assessment should coincide with the introduction of novel technologies aimed at minimizing exposure (i.e., risk management). Assessment must consider various departments and health operators susceptible to ADs contamination, with a focus extended beyond worst-case scenarios, also considering activities like surface cleaning and logistical tasks related to ADs management. A comprehensive approach in ADs risk assessment enables the evaluation of distinct substance behaviors and subsequent exposure routes, affording a more holistic understanding of potential risks.</p>","PeriodicalId":49833,"journal":{"name":"Medicina Del Lavoro","volume":"115 2","pages":"e2024012"},"PeriodicalIF":2.4,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11181217/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140871060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-24DOI: 10.23749/mdl.v115i2.15532
Gabriele D'Ettorre, Prisco Piscitelli, Vincenza Pellicani, Roberta Tornese, Giancarlo Ceccarelli, Gabriella D'Ettorre, Giuseppe La Torre
Background: Coronary artery disease (CAD) prevention in shift workers (SWs) poses a significant challenge worldwide, as CAD remains a major cause of mortality and disability. In the past, SWs were found at higher risk of CAD than non-s SWs. Nevertheless, the pathogenic mechanism between shift work and CAD to date is unclear. This systematic review aims to enhance understanding of the risk of CAD occurrence in SWs.
Methods: A systematic literature review was conducted from January 2013 to December 2023. MEDLINE/Pubmed databases were used initially, and additional relevant studies were searched from references. Shift work was defined as any schedule outside traditional shifts, including the night shift.
Results: Fifteen pertinent papers were categorized into risk assessment or risk management. Findings demonstrated an increased risk of CAD among SWs compared to non-SWs, with an increased CAD risk observed for both shift work and night shift work.
Discussion: Duration-response associations indicate that greater shift exposure is linked to higher CAD risk. SWs incur an increased risk of CAD through the atherosclerotic process. As shift work duration increases as the risk of atherosclerosis is higher, workers demonstrate a higher prevalence and severity of coronary artery plaques.
Conclusions: The evidence-based results underscore the increased risk of CAD in SWs and are sufficient for proposing guidelines aimed at reducing the risk of CAD in SWs and at managing people with CAD in return to work characterized by disrupted circadian rhythms.
{"title":"Occupational Risk for Coronary Artery Disease in Shift Workers - A Systematic Review.","authors":"Gabriele D'Ettorre, Prisco Piscitelli, Vincenza Pellicani, Roberta Tornese, Giancarlo Ceccarelli, Gabriella D'Ettorre, Giuseppe La Torre","doi":"10.23749/mdl.v115i2.15532","DOIUrl":"10.23749/mdl.v115i2.15532","url":null,"abstract":"<p><strong>Background: </strong>Coronary artery disease (CAD) prevention in shift workers (SWs) poses a significant challenge worldwide, as CAD remains a major cause of mortality and disability. In the past, SWs were found at higher risk of CAD than non-s SWs. Nevertheless, the pathogenic mechanism between shift work and CAD to date is unclear. This systematic review aims to enhance understanding of the risk of CAD occurrence in SWs.</p><p><strong>Methods: </strong>A systematic literature review was conducted from January 2013 to December 2023. MEDLINE/Pubmed databases were used initially, and additional relevant studies were searched from references. Shift work was defined as any schedule outside traditional shifts, including the night shift.</p><p><strong>Results: </strong>Fifteen pertinent papers were categorized into risk assessment or risk management. Findings demonstrated an increased risk of CAD among SWs compared to non-SWs, with an increased CAD risk observed for both shift work and night shift work.</p><p><strong>Discussion: </strong>Duration-response associations indicate that greater shift exposure is linked to higher CAD risk. SWs incur an increased risk of CAD through the atherosclerotic process. As shift work duration increases as the risk of atherosclerosis is higher, workers demonstrate a higher prevalence and severity of coronary artery plaques.</p><p><strong>Conclusions: </strong>The evidence-based results underscore the increased risk of CAD in SWs and are sufficient for proposing guidelines aimed at reducing the risk of CAD in SWs and at managing people with CAD in return to work characterized by disrupted circadian rhythms.</p>","PeriodicalId":49833,"journal":{"name":"Medicina Del Lavoro","volume":"115 2","pages":"e2024015"},"PeriodicalIF":2.7,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11181222/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140867003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-24DOI: 10.23749/mdl.v115i2.15569
Marika D'Agostini, Giulia Collatuzzo, Federica Teglia, Paolo Boffetta
Background: Our objective was to study the association between occupational exposure to diesel exhaust (DE) and skin cancer.
Methods: A systematic review following STROBE guidelines and PECOS criteria was conducted to identify cohort studies describing the association between occupational DE exposure and the risk of skin cancer. We extracted 12 independent risk estimates for melanoma skin cancer (MSC), 8 for non-melanoma skin cancer (NMSC), and 3 for skin cancer not otherwise specified (SC-NOS). Random effects meta-analyses were performed, site-specific and stratified by geographic region and quality score. 95% confidence intervals (CI) were reported. Between-study heterogeneity and potential publication bias were investigated.
Results: There was no overall evidence of an increased risk of MSC [RR=0.90, 95% CI: 0.73-1.11; I2=92.86%, 95% CI: 82.83-97.03%], NMSC [RR=1.04, 95% CI: 0.88-1.23; I2=60.79%, 95% CI: 0-87.34%] or SC-NOS [RR=0.72, 95% CI: 0.54-0.97; I2=26.60%, 95% CI: 0-94.87%] in workers exposed to DE. No difference between low-quality and high-quality studies was found. A stratified analysis by geographical region did not reveal any significant differences. There was no evidence of publication bias.
Conclusions: No evidence of an association between skin cancer and occupational DE exposure was found. Residual confounding and other sources of bias cannot be ruled out.
{"title":"Risk of Skin Cancer in Workers Exposed to Diesel Exhaust: A Systematic Review and Meta-Analysis of Cohort Studies.","authors":"Marika D'Agostini, Giulia Collatuzzo, Federica Teglia, Paolo Boffetta","doi":"10.23749/mdl.v115i2.15569","DOIUrl":"10.23749/mdl.v115i2.15569","url":null,"abstract":"<p><strong>Background: </strong>Our objective was to study the association between occupational exposure to diesel exhaust (DE) and skin cancer.</p><p><strong>Methods: </strong>A systematic review following STROBE guidelines and PECOS criteria was conducted to identify cohort studies describing the association between occupational DE exposure and the risk of skin cancer. We extracted 12 independent risk estimates for melanoma skin cancer (MSC), 8 for non-melanoma skin cancer (NMSC), and 3 for skin cancer not otherwise specified (SC-NOS). Random effects meta-analyses were performed, site-specific and stratified by geographic region and quality score. 95% confidence intervals (CI) were reported. Between-study heterogeneity and potential publication bias were investigated.</p><p><strong>Results: </strong>There was no overall evidence of an increased risk of MSC [RR=0.90, 95% CI: 0.73-1.11; I2=92.86%, 95% CI: 82.83-97.03%], NMSC [RR=1.04, 95% CI: 0.88-1.23; I2=60.79%, 95% CI: 0-87.34%] or SC-NOS [RR=0.72, 95% CI: 0.54-0.97; I2=26.60%, 95% CI: 0-94.87%] in workers exposed to DE. No difference between low-quality and high-quality studies was found. A stratified analysis by geographical region did not reveal any significant differences. There was no evidence of publication bias.</p><p><strong>Conclusions: </strong>No evidence of an association between skin cancer and occupational DE exposure was found. Residual confounding and other sources of bias cannot be ruled out.</p>","PeriodicalId":49833,"journal":{"name":"Medicina Del Lavoro","volume":"115 2","pages":"e2024010"},"PeriodicalIF":2.7,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11181223/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140867912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}