The Okinawa Trough (OT) is a critical archive of western Pacific paleoceanography, yet the glacial-interglacial evolution of its circulation and bottom-water redox conditions remain poorly constrained. This study provides a multi-proxy reconstruction from core CS2 in the central OT, revealing a 19-ka history of Kuroshio Current (KC) and intermediate water ventilation for bottom-water oxygenation. Our results show that during the last glaciation, lower sea levels isolated the trough, reducing KC inflow as evidenced by decreased abundances of tropical-subtropical planktonic foraminifera and a shoaled thermocline. Concurrently, bottom-water hypoxia developed, indicated by elevated infaunal benthic foraminifera, lower Mn/Al ratios, and reduced CaCO3 content, collectively suggesting that the absence or shift of KC was the primary driver of poor ventilation. Furthermore, an anti-phase relationship between hypoxia intensity and North Pacific Intermediate Water (NPIW) ventilation can be observed: enhanced NPIW ventilation (Heinrich Stadial 1 and Younger Dryas) corresponded to weakened hypoxia, whereas reduced ventilation during the Bølling/Allerød intensified hypoxia. The consistently low CaCO3 content precluded the possibility of hypoxia caused by organic matter consumption, further supporting the conclusion that glacial NPIW ventilation might be another modulator of bottom water oxygenation. During the postglacial period, the return of the KC into the OT improved bottom-water ventilation by reducing stratification and alleviated hypoxia. This study elucidates the evolution of circulation and bottom-water redox conditions to better understand organic carbon burial in the OT. Furthermore, the redox history provides a key mid-latitude archive for assessing the influence of glacial NPIW.
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