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Bacteriological Trends of Chronic Mucosal Otitis Media in a Tertiary Care Hospital in the Northern Region of Bangladesh 孟加拉国北部地区一家三级医院慢性黏膜性中耳炎的细菌学发展趋势
Pub Date : 2024-02-06 DOI: 10.3329/mumcj.v6i2.71388
Md Asif Anowar, Md Abdullah Al Mamun, Md Shirajul Islam Mondal, A. R. E. Mahbub, Syed Nafi Mahdee, Amzad Hossain, Kazi Mushfika Haque
Background: Chronic otitis media (COM) is a disease of multiple etiology caused by bacteria and its importance lies in its chronicity and awful complications. The microbiological study shows the growth of a lot of organisms, frequently multiple and those differ based on geographical variation, patient population, climate, and many other factors.Objective: To evaluate current bacteriological trends of ear infections in patients with chronic otitis media which will be beneficial for appropriate treatment as well as for reducing complications. The study also focuses on rapid diagnosis by exploring other factors like age and sex-wise distribution, socioeconomic status, distribution of patients according to the type of dwelling, and bathing habits of patients.Methods: This cross-sectional, observational study was conducted in the Department of ENT and Head-Neck Surgery, Rangpur Medical College Hospital in Rangpur, a northern district of Bangladesh, over 6 months on a total of 80 patients who had attended outpatient and inpatient departments. Aural swab was taken from the discharging ears which were inoculated on blood agar and MacConkey’s agar media. The organism pattern was then tabled based on the culture reports.Results: The most common bacteria causing COM was Pseudomonas aeruginosa in (45.0%) followed by Staph. aureus (27.5%), mixed isolates in 8.75%, E. coli in 5%, Proteus in 3.75%, S. pneumoniae in 2.5%, and Klebsiella in 1.25%.Conclusion: The study proved to be useful for clinicians in management of COM and its complications. Early and effective microbiological diagnosis and intervention is the best solution. From this study, it is observed that Pseudomonas aeruginosa is the commonest pathogen for bacterial ear disease followed by S. Aureus.Mugda Med Coll J. 2023; 6(2): 83-87
背景:慢性中耳炎(COM)是一种由细菌引起的多种病因的疾病,其重要性在于慢性和可怕的并发症。微生物学研究显示,慢性中耳炎的病原菌种类繁多,经常是多种病原菌,而且这些病原菌因地域差异、患者人群、气候和许多其他因素而有所不同:评估当前慢性中耳炎患者耳部感染的细菌学趋势,这将有利于适当的治疗和减少并发症。本研究还重点探讨了其他因素,如年龄和性别分布、社会经济状况、根据居住类型划分的患者分布情况以及患者的洗澡习惯等,从而实现快速诊断:这项横断面观察性研究在孟加拉国北部朗布尔地区朗布尔医学院医院耳鼻咽喉头颈外科进行,历时 6 个月,共有 80 名患者在门诊和住院部就诊。从出院的耳朵上取耳拭子,接种在血琼脂和麦康凯琼脂培养基上。然后根据培养报告列出细菌模式:结果:导致 COM 的最常见细菌是铜绿假单胞菌(45.0%),其次是金黄色葡萄球菌(27.5%)、混合分离菌(8.75%)、大肠杆菌(5%)、变形杆菌(3.75%)、肺炎双球菌(2.5%)和克雷伯氏菌(1.25%):这项研究对临床医生处理 COM 及其并发症很有帮助。早期有效的微生物诊断和干预是最佳解决方案。从本研究中可以看出,铜绿假单胞菌是细菌性耳病最常见的病原体,其次是金黄色葡萄球菌:83-87
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引用次数: 0
Dengue Vaccine: Past, Present and Future 登革热疫苗:过去、现在和未来
Pub Date : 2024-02-06 DOI: 10.3329/mumcj.v6i2.71267
Salma Ahmed
Abstract not available Mugda Med Coll J. 2023; 6(2): 48-50
摘要不详 Mugda Med Coll J. 2023; 6(2):48-50
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引用次数: 0
Demographic Characteristics and Clinical Factors of the Patients Suffering from Osteoarthritis of Hand – A Study Done in A Tertiary Specialized Hospital in Bangladesh 手部骨关节炎患者的人口统计学特征和临床因素--孟加拉国一家三级专科医院的一项研究
Pub Date : 2024-02-06 DOI: 10.3329/mumcj.v6i2.71376
Md Zobayed Sultan, Saida Sharmin, Razia Sultana, Merina Tanzil
Background: Osteoarthritis (OA) is one of the most common forms of arthritis. Hand OA is a heterogeneous, age and gender-dependent disorder, occurring more frequently in postmenopausal women over 50 years of age.Objective: This study aims to identify demographic patterns and factors associated with osteoarthritis of the hand among patients attending a tertiary-level hospital in Bangladesh.Methods: This cross-sectional study was done in the Department of Orthopedics, Shaheed Ziaur Rahman Medical College Hospital, Bogura, Bangladesh, between January and December of 2021. A total of 90 patients with OA of hands were included in this study. All patients were selected conveniently and informed written consent of the patients was taken. Participant data were collected through face-to-face interviews using a semi-structured questionnaire. Statistical analyses were done with Statistical Package for Social Science (SPSS) version 25.0. Quantitative variables were analyzed by mean and standard deviation while qualitative variables were summarized by percentage. Results: In this study, the age distribution of the patients ranges from e”40 years to d”75 years irrespective of sex. The mean age of the patients of both sexes was 56.6±8.72 years. Among those 90 patients, 35 persons (38.9%) were male and 55 (61.1%) were female. Most of the patients are housewives 38 (42.22%). Most of the women (87.27%) are menopausal among the total 55 female patients. Only 13 (14.45%) persons had a previous history of a hand injury, and 20 (22.22%) persons had a habit of smoking or previously smokers. Most of the subjects 78 (86.67%) were right-hand dominant and a maximum of 67 (74.45%) persons enrolled in this study showed priority affected CMC1 OA to the dominant hand. Most of them (75.55%) took medications for treatment for arthritis.Conclusion: Our study revealed that osteoarthritis of the hands is predominant in females and affects mostly the right hand. Further high-quality studies examining the risk factors for hand osteoarthritis are needed to replicate these findings and determine modifiable factors in symptomatic patients.Mugda Med Coll J. 2023; 6(2): 77-82
背景:骨关节炎(OA)是最常见的关节炎之一。手部骨关节炎是一种异质性疾病,与年龄和性别有关,多发于 50 岁以上的绝经后妇女:本研究旨在确定孟加拉国一家三级医院就诊患者的人口统计模式以及与手部骨关节炎相关的因素:这项横断面研究于 2021 年 1 月至 12 月在孟加拉国博古拉 Shaheed Ziaur Rahman 医学院医院骨科进行。本研究共纳入了 90 名手部 OA 患者。所有患者均在方便的情况下被选中,并获得了患者的知情书面同意。研究采用半结构化问卷,通过面对面访谈的方式收集参与者的数据。统计分析采用社会科学统计软件包(SPSS)25.0 版。定量变量按平均值和标准差进行分析,定性变量按百分比进行总结。结果在这项研究中,患者的年龄分布从 e "40 岁到 d "75 岁不等,不分性别。男女患者的平均年龄为(56.6±8.72)岁。在这 90 名患者中,男性 35 人(占 38.9%),女性 55 人(占 61.1%)。大多数患者是家庭主妇,有 38 人(42.22%)。在总共 55 名女性患者中,大多数女性(87.27%)处于更年期。只有 13 人(14.45%)曾有过手部受伤的病史,20 人(22.22%)有吸烟习惯或曾经吸烟。大多数受试者(78 人,占 86.67%)的惯用手都是右手,最多有 67 人(74.45%)的惯用手的 CMC1 OA 优先受影响。他们中的大多数人(75.55%)服用药物治疗关节炎:我们的研究表明,手部骨关节炎以女性居多,且主要影响右手。需要对手部骨关节炎的风险因素进行进一步的高质量研究,以复制这些发现并确定有症状患者的可调节因素:77-82
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引用次数: 0
Determinants of Type 2 Diabetes Mellitus among Children and Adolescents Attending A Tertiary Specialized Hospital in Bangladesh 在孟加拉国一家三级专科医院就诊的儿童和青少年患 2 型糖尿病的决定因素
Pub Date : 2024-02-06 DOI: 10.3329/mumcj.v6i2.71269
S. Tayyeb, B. Zabeen, F. Naz, K. Azad
Background: Type 2 diabetes in children and adolescents has increased in frequency around the world over the past two decades. The worldwide epidemic of childhood obesity has been accompanied by an increase in the incidence of type 2 diabetes in children and adolescents.Objective: To observe the determinants of type 2 diabetes mellitus among children and adolescents attending a tertiary specialized hospital in Bangladesh.Methods: This cross-sectional, descriptive study was done on a total of 151 children and adolescents attending the pediatric diabetic outpatient department (OPD) of Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine, and Metabolic Disorders (BIRDEM) Hospital, Dhaka, Bangladesh. The sampling technique was purposive. All patients who came to the hospital between July to December 2017 were included. Data was collected through a structured questionnaire.Results: Among 151 respondents, 98 were in the age group of 10-14 years (64.9%), female to male ratio of 1.22:1. The majority belonged to a high used to lead socio-economic class. Regarding food habits, 55.6% had a history of eating fast food regularly and used to lead a sedentary lifestyle with a lack of exercise. 43.7% of children and adolescents were obese 76.8% had high cholesterol and 84.1% had high triglyceride levels. Most of the children had a positive family history of type 2 diabetes mellitus (74.8%).Conclusion: Our study reflects that determinants like obesity, physical inactivity, eating habits, and family history are important factors in the development of type 2 diabetes mellitus in children and adolescents. Mugda Med Coll J. 2023; 6(2): 51-56
背景:在过去的二十年里,儿童和青少年患 2 型糖尿病的频率在全球范围内有所上升。儿童肥胖症在全球流行的同时,儿童和青少年 2 型糖尿病的发病率也在增加:观察在孟加拉国一家三级专科医院就诊的儿童和青少年患 2 型糖尿病的决定因素:这项横断面描述性研究的对象是孟加拉国达卡孟加拉糖尿病、内分泌和代谢紊乱研究与康复研究所医院(BIRDEM)儿科糖尿病门诊部(OPD)的151名儿童和青少年。抽样技术为目的性抽样。所有在2017年7月至12月期间来医院就诊的患者均被纳入其中。通过结构化问卷收集数据:在 151 名受访者中,98 人年龄在 10-14 岁之间(占 64.9%),男女比例为 1.22:1。大多数人属于社会经济地位较高的阶级。在饮食习惯方面,55.6%的人有经常吃快餐的习惯,并习惯久坐不动、缺乏锻炼的生活方式。43.7%的儿童和青少年肥胖,76.8%的儿童和青少年胆固醇偏高,84.1%的儿童和青少年甘油三酯水平偏高。大多数儿童都有 2 型糖尿病家族史(74.8%):我们的研究表明,肥胖、缺乏运动、饮食习惯和家族病史等决定性因素是儿童和青少年罹患 2 型糖尿病的重要因素。Mugda Med Coll J. 2023; 6(2):51-56
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引用次数: 0
Dengue Vaccine: Past, Present and Future 登革热疫苗:过去、现在和未来
Pub Date : 2024-02-06 DOI: 10.3329/mumcj.v6i2.71267
Salma Ahmed
Abstract not available Mugda Med Coll J. 2023; 6(2): 48-50
摘要不详 Mugda Med Coll J. 2023; 6(2):48-50
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引用次数: 0
Growth Status and Glycemic Control of Diabetic Children in a Tertiary Care Hospital in Dhaka City 达卡市一家三级医院糖尿病儿童的生长状况和血糖控制情况
Pub Date : 2024-02-06 DOI: 10.3329/mumcj.v6i2.71392
F. Naz, S. Tayyeb, B. Zabeen, Adnan Yusuf Choudhury
Childhood growth is a critical indicator of the health status of a child which also determines the overall developmental potential in adult life. Along with an increased risk of developing various co-morbidities, diabetic children remain susceptible to growth delay in terms of height and weight. Thus it is necessary to evaluate their growth status about their glycemic control. This cross-sectional study observed 148 sequentially selected diabetic children aged 9 to 15 years, with 5 years of diabetes duration attending a tertiary level hospital. Data regarding their anthropometric measurements including height and weight, HbA1c status, and diabetic history has been collected. HbA1c level is a significant determinant of height, weight, and BMI of the study subjects (p<0.05). The age at diagnosis of diabetes was found to have a significant impact on the height of the girls and weight of both boys and girls and also on their HbA1c level, where, in all groups, the age at diagnosis at 5 to 9 years found to have the highest proportion of children whose growth was less than the reference range. The duration of diabetes in this study was not related to the anthropometric measurement of the children (p>0.05) although it was significantly associated with their HbA1c level (p<0.05). This study's results observed growth alteration among children with diabetes in association with their HbA1c level and age at diagnosis, which suggests that diabetic children should undertake routine monitoring of growth and glycemic control to provide timely and adequate interventions to prevent growth delay among them.Mugda Med Coll J. 2023; 6(2): 88-92
儿童生长发育是衡量儿童健康状况的重要指标,也决定着儿童成年后的整体发展潜力。患糖尿病的儿童在身高和体重方面的发育迟缓,会增加患各种并发症的风险。因此,有必要对他们的血糖控制生长状况进行评估。这项横断面研究观察了在一家三级医院就诊的 148 名按顺序选出的 9 至 15 岁糖尿病患儿,他们的糖尿病病程均为 5 年。研究收集了他们的人体测量数据,包括身高和体重、HbA1c 状态和糖尿病史。HbA1c 水平是研究对象身高、体重和体重指数的重要决定因素(P0.05),但与 HbA1c 水平有显著关联(P<0.05)。这项研究结果表明,糖尿病儿童的生长改变与他们的 HbA1c 水平和诊断年龄有关,这表明糖尿病儿童应进行生长和血糖控制的常规监测,以提供及时和充分的干预措施,防止他们的生长发育延迟:88-92
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引用次数: 0
Association between Serum Ferritin and Insulin Resistance Markers with Distinct Glycemic Profiles in an Adult Bangladeshi Population 孟加拉成年人群血清铁蛋白和胰岛素抵抗标志物与不同血糖特征之间的关系
Pub Date : 2024-02-06 DOI: 10.3329/mumcj.v6i2.71290
Tasnim Ara Jhilk, Ehsanul Haque Khan, Shamima Parvin, Mohammad Mohsin Mia, Israt Jahan, Shahanaz Akter
Background: Type 2 diabetes mellitus (T2DM) is a global health concern. Around 56% of subjects in Bangladesh go undiagnosed, increasing the risk of stroke and cardiovascular issues. Iron stores' impact on diabetes is gaining attention, with ferritin as a key biomarker. Hyperferritinemia probably contributes to insulin resistance and subsequently to decreased insulin secretion, causing the development of insulin resistance. The link between ferritin and insulin resistance (IR) varies based on ethnicity, gender, and glycemic state.Objectives: This study investigates serum ferritin levels in different glycemic stages and explores potential correlations between ferritin and insulin resistance markers (blood glucose, serum insulin, and HOMA-IR)Methods: The study was conducted at the Department of Biochemistry, Sir Salimullah Medical College, Dhaka, Bangladesh, from March 2018 to February 2019. A total of 140 subjects were included to conduct this study. Participants were categorized into three groups: those with normal fasting glucose (NFG group), impaired fasting glucose (IFG group), and newly diagnosed type 2 diabetes mellitus (Diabetic group) according to WHO (2006) criteria. A purposive convenient sampling method was used, focusing on adults aged 25 to 55 years. Exclusion criteria were applied to eliminate individuals with inflammatory diseases, chronic conditions, major cardiovascular events, anemia, or specific medications that could affect ferritin levels.Results: The study found that serum ferritin levels significantly differed among three glycemic groups (NFG, IFG, and T2DM) with higher levels in T2DM. IFG and T2DM groups also had elevated serum insulin and HOMA-IR. Serum ferritin correlated strongly with fasting blood glucose, serum insulin, HOMA-IR, and BMI. The highest tertile of ferritin levels were associated with the IFG & diabetic group.Conclusion. Elevated serum ferritin levels in IFG and type 2 diabetes may significantly impact glucose regulation. Compared to NFG, there are high insulin resistance markers (fasting insulin, glucose, HOMA-IR) in T2DM and IFG. They have crucial implications for both therapy and prognosis in these conditions.Mugda Med Coll J. 2023; 6(2): 57-63
背景:2 型糖尿病(T2DM)是全球关注的健康问题。孟加拉国约有 56% 的患者未得到诊断,增加了中风和心血管问题的风险。铁储存对糖尿病的影响日益受到关注,而铁蛋白是一个关键的生物标志物。高铁蛋白血症可能会导致胰岛素抵抗,进而导致胰岛素分泌减少,引起胰岛素抵抗。铁蛋白与胰岛素抵抗(IR)之间的联系因种族、性别和血糖状态而异:本研究调查了不同血糖阶段的血清铁蛋白水平,并探讨了铁蛋白与胰岛素抵抗指标(血糖、血清胰岛素和 HOMA-IR)之间的潜在相关性:研究于 2018 年 3 月至 2019 年 2 月在孟加拉国达卡萨利穆拉爵士医学院生物化学系进行。本研究共纳入 140 名受试者。根据世界卫生组织(2006 年)的标准,参与者被分为三组:空腹血糖正常组(NFG 组)、空腹血糖受损组(IFG 组)和新诊断的 2 型糖尿病组(Diabetic 组)。研究采用了有目的的方便抽样法,主要针对 25 至 55 岁的成年人。采用排除标准以排除患有炎症性疾病、慢性病、重大心血管事件、贫血或服用可能影响铁蛋白水平的特定药物的人:研究发现,血清铁蛋白水平在三个血糖组(NFG、IFG 和 T2DM)之间存在显著差异,T2DM 组的铁蛋白水平更高。IFG 和 T2DM 组的血清胰岛素和 HOMA-IR 也有所升高。血清铁蛋白与空腹血糖、血清胰岛素、HOMA-IR 和体重指数密切相关。铁蛋白水平的最高三分位数与 IFG 和糖尿病组相关。结论:IFG 和 2 型糖尿病患者血清铁蛋白水平升高可能会严重影响血糖调节。与 NFG 相比,T2DM 和 IFG 的胰岛素抵抗指标(空腹胰岛素、血糖、HOMA-IR)较高。这些指标对这些疾病的治疗和预后都有重要影响:57-63
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引用次数: 0
Understanding Burnout in Surgeons: How to Avoid Burnout? 了解外科医生的职业倦怠:如何避免职业倦怠?
Pub Date : 2024-02-06 DOI: 10.3329/mumcj.v6i2.71412
Mohammed Shadrul Alam
Although surgeons work in more stressful medical fields, surgeons are generally considered to offer some of the best lifestyles among physicians. Burnout among surgeons is increasing at an alarming rate. The goals of this review are to increase awareness of the symptoms, causes, and consequences of surgeons’ burnout and how to avoid burnout? Surgeons’ burnout is largely attributed to work-related factors and personal -related factors. Burnout has many potential adverse consequences including professional consequences and personal consequences. The recovery from surgeon’s burnout can take months or longer, therefore it’s important to try to avoid it in the first place through preventative strategies. Mugda Med Coll J. 2023; 6(2): 99-106
虽然外科医生在压力更大的医疗领域工作,但人们普遍认为外科医生是内科医生中生活方式最好的。外科医生的职业倦怠正以惊人的速度增加。本综述旨在提高人们对外科医生职业倦怠的症状、原因和后果以及如何避免职业倦怠的认识。外科医生的职业倦怠主要归因于工作相关因素和个人相关因素。职业倦怠有许多潜在的不良后果,包括职业后果和个人后果。外科医生职业倦怠的恢复可能需要数月甚至更长的时间,因此首先要通过预防策略来尽量避免职业倦怠。Mugda Med Coll J. 2023; 6(2):99-106
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引用次数: 0
Association between Serum Ferritin and Insulin Resistance Markers with Distinct Glycemic Profiles in an Adult Bangladeshi Population 孟加拉成年人群血清铁蛋白和胰岛素抵抗标志物与不同血糖特征之间的关系
Pub Date : 2024-02-06 DOI: 10.3329/mumcj.v6i2.71290
Tasnim Ara Jhilk, Ehsanul Haque Khan, Shamima Parvin, Mohammad Mohsin Mia, Israt Jahan, Shahanaz Akter
Background: Type 2 diabetes mellitus (T2DM) is a global health concern. Around 56% of subjects in Bangladesh go undiagnosed, increasing the risk of stroke and cardiovascular issues. Iron stores' impact on diabetes is gaining attention, with ferritin as a key biomarker. Hyperferritinemia probably contributes to insulin resistance and subsequently to decreased insulin secretion, causing the development of insulin resistance. The link between ferritin and insulin resistance (IR) varies based on ethnicity, gender, and glycemic state.Objectives: This study investigates serum ferritin levels in different glycemic stages and explores potential correlations between ferritin and insulin resistance markers (blood glucose, serum insulin, and HOMA-IR)Methods: The study was conducted at the Department of Biochemistry, Sir Salimullah Medical College, Dhaka, Bangladesh, from March 2018 to February 2019. A total of 140 subjects were included to conduct this study. Participants were categorized into three groups: those with normal fasting glucose (NFG group), impaired fasting glucose (IFG group), and newly diagnosed type 2 diabetes mellitus (Diabetic group) according to WHO (2006) criteria. A purposive convenient sampling method was used, focusing on adults aged 25 to 55 years. Exclusion criteria were applied to eliminate individuals with inflammatory diseases, chronic conditions, major cardiovascular events, anemia, or specific medications that could affect ferritin levels.Results: The study found that serum ferritin levels significantly differed among three glycemic groups (NFG, IFG, and T2DM) with higher levels in T2DM. IFG and T2DM groups also had elevated serum insulin and HOMA-IR. Serum ferritin correlated strongly with fasting blood glucose, serum insulin, HOMA-IR, and BMI. The highest tertile of ferritin levels were associated with the IFG & diabetic group.Conclusion. Elevated serum ferritin levels in IFG and type 2 diabetes may significantly impact glucose regulation. Compared to NFG, there are high insulin resistance markers (fasting insulin, glucose, HOMA-IR) in T2DM and IFG. They have crucial implications for both therapy and prognosis in these conditions.Mugda Med Coll J. 2023; 6(2): 57-63
背景:2 型糖尿病(T2DM)是全球关注的健康问题。孟加拉国约有 56% 的患者未得到诊断,增加了中风和心血管问题的风险。铁储存对糖尿病的影响日益受到关注,而铁蛋白是一个关键的生物标志物。高铁蛋白血症可能会导致胰岛素抵抗,进而导致胰岛素分泌减少,引起胰岛素抵抗。铁蛋白与胰岛素抵抗(IR)之间的联系因种族、性别和血糖状态而异:本研究调查了不同血糖阶段的血清铁蛋白水平,并探讨了铁蛋白与胰岛素抵抗指标(血糖、血清胰岛素和 HOMA-IR)之间的潜在相关性:研究于 2018 年 3 月至 2019 年 2 月在孟加拉国达卡萨利穆拉爵士医学院生物化学系进行。本研究共纳入 140 名受试者。根据世界卫生组织(2006 年)的标准,参与者被分为三组:空腹血糖正常组(NFG 组)、空腹血糖受损组(IFG 组)和新诊断的 2 型糖尿病组(Diabetic 组)。研究采用了有目的的方便抽样法,主要针对 25 至 55 岁的成年人。采用排除标准以排除患有炎症性疾病、慢性病、重大心血管事件、贫血或服用可能影响铁蛋白水平的特定药物的人:研究发现,血清铁蛋白水平在三个血糖组(NFG、IFG 和 T2DM)之间存在显著差异,T2DM 组的铁蛋白水平更高。IFG 和 T2DM 组的血清胰岛素和 HOMA-IR 也有所升高。血清铁蛋白与空腹血糖、血清胰岛素、HOMA-IR 和体重指数密切相关。铁蛋白水平的最高三分位数与 IFG 和糖尿病组相关。结论:IFG 和 2 型糖尿病患者血清铁蛋白水平升高可能会严重影响血糖调节。与 NFG 相比,T2DM 和 IFG 的胰岛素抵抗指标(空腹胰岛素、血糖、HOMA-IR)较高。这些指标对这些疾病的治疗和预后都有重要影响:57-63
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引用次数: 0
Bacteriological Study and Antibacterial Susceptibility in Ludwig’s Angina in a Tertiary Level Hospital in Dhaka, Bangladesh 孟加拉国达卡一家三级医院路德维格心绞痛患者的细菌学研究和抗菌敏感性
Pub Date : 2024-02-06 DOI: 10.3329/mumcj.v6i2.71369
A. R. E. Mahbub, Abdullah Al Mamun, Rokhsana Sarmin, Syed Sanaul Islam, Rashedul Islam, A. N. E. As Sayeed, Md Asif Anowar
Background: The knowledge of the local pattern of infection and antibacterial sensitivity in Ludwig’s angina is essential to enable efficacious treatment for it.Objective: To find out the pattern of bacteria responsible for developing Ludwig’s angina and their antibacterial susceptibility.Methods: It is a prospective, observational type of study carried out in the Department of Otolaryngology & Head-Neck Surgery, Dhaka Medical College Hospital, Dhaka, and the Department of Clinical Microbiology, ICDDR, B, Dhaka, Bangladesh, between April and September of 2016. A total of 100 patients were included in this study.Results: This study was done among 100 patients. In this study, 42 cases (42%) were in the 31-45 years age group. The male patients were 60 (60%) and females were 40 (40%). Majority of patients 70(70%) came from poor class family with educational level up to HSC (75%), maximum 35(35%) patients use meswak to clean teeth, 70 (70%) patients came from rural area, 70 (70%) patients had dental infection, 25 (25%) patients had diabetes mellitus, all the cases (100%) presented with swelling in the floor of the mouth and neck, pain and tenderness and fever. The major complication was necrotizing fasciitis 8 (8%), 36 (36%) patients were discharged within 1-2 weeks after treatment, Streptococcus 40 (40%) was the most common organism and the most effective antibiotic was Ceftriaxone (65%).Conclusion: The most frequently isolated organism in Ludwig’s angina is Streptococcus and sensitivity results showed a majority of isolates are susceptible to Ceftriaxone.Mugda Med Coll J. 2023; 6(2): 71-76
背景:了解路德维希心绞痛的局部感染模式和抗菌敏感性对有效治疗该病至关重要:方法:这是一项前瞻性、观察性研究:这是一项前瞻性、观察型研究,于2016年4月至9月期间在孟加拉国达卡医学院附属医院耳鼻咽喉头颈外科和达卡ICDDR B临床微生物学系开展。本研究共纳入 100 名患者:本研究在 100 名患者中进行。其中,42 例(42%)患者年龄在 31-45 岁之间。男性患者为 60 人(60%),女性患者为 40 人(40%)。大多数患者(70%)来自贫困家庭,受教育程度最高为高中(75%),最多有 35(35%)名患者使用美沙酮清洁牙齿,70(70%)名患者来自农村地区,70(70%)名患者患有牙科感染,25(25%)名患者患有糖尿病,所有病例(100%)均表现为口腔底部和颈部肿胀、疼痛、触痛和发烧。主要并发症是坏死性筋膜炎(8%),36 名患者(36%)在治疗后 1-2 周内出院,链球菌 40(40%)是最常见的病原体,最有效的抗生素是头孢曲松(65%):结论:路德维希心绞痛患者中最常分离到的病原体是链球菌,药敏结果显示大多数分离菌对头孢曲松敏感:71-76
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Mugda Medical College Journal
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