Maria Angela Vittoria Licata, Lucia Maria Porro, Giacomo Sgalla, Luca Richeldi
A 59-year-old patient without a history of pulmonary disease presented with episodes of hemoptysis and acute respiratory failure after being treated for metastatic breast cancer with fulvestrant and palbociclib. The high-resolution chest CT revealed diffuse ground glass opacities and diffuse smooth thickening of the interlobular septa and peribronchovascular interstitium, consistent with drug-induced interstitial lung disease (DIILD). A few days of high-dose steroid treatment increased the patient's PaO2/FiO2 from 75 to 200. Following hospital discharge, the oncologist resumed fulvestrant therapy, with no further adverse events occurring during subsequent follow-up.
{"title":"Drug-Induced Interstitial Lung Disease in a patient treated with a combination of palbociclib and fulvestrant","authors":"Maria Angela Vittoria Licata, Lucia Maria Porro, Giacomo Sgalla, Luca Richeldi","doi":"10.4081/cdr.11.11679","DOIUrl":"https://doi.org/10.4081/cdr.11.11679","url":null,"abstract":"A 59-year-old patient without a history of pulmonary disease presented with episodes of hemoptysis and acute respiratory failure after being treated for metastatic breast cancer with fulvestrant and palbociclib. The high-resolution chest CT revealed diffuse ground glass opacities and diffuse smooth thickening of the interlobular septa and peribronchovascular interstitium, consistent with drug-induced interstitial lung disease (DIILD). A few days of high-dose steroid treatment increased the patient's PaO2/FiO2 from 75 to 200. Following hospital discharge, the oncologist resumed fulvestrant therapy, with no further adverse events occurring during subsequent follow-up.","PeriodicalId":500149,"journal":{"name":"Chest disease reports","volume":"106 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135013498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Georgi Yankov, Magdalena Aleksieva, Asen Keltchev, Evgeni Mekov
Inflammatory Myofibroblastic Tumor (IMT) is a benign tumor that is extremely rare. We present a 54-year-old man who has received 23 years of conservative treatment for IMT, respiratory infections, aspergillosis, and hemoptysis. A left intrapericardial pneumonectomy was performed with efficacy. The left atrial auricle lesion created a massive hemorrhage during chest closure due to contact with the staplers of the left pulmonary artery stapler line. The hemorrhaging was stopped immediately. The patient has entirely recovered one year after surgery, and no adverse events or relapses have occurred.
{"title":"Central lung inflammatory myofibroblastic tumor after aspergillosis and total occlusion of the left pulmonary artery","authors":"Georgi Yankov, Magdalena Aleksieva, Asen Keltchev, Evgeni Mekov","doi":"10.4081/cdr.10.11957","DOIUrl":"https://doi.org/10.4081/cdr.10.11957","url":null,"abstract":"Inflammatory Myofibroblastic Tumor (IMT) is a benign tumor that is extremely rare. We present a 54-year-old man who has received 23 years of conservative treatment for IMT, respiratory infections, aspergillosis, and hemoptysis. A left intrapericardial pneumonectomy was performed with efficacy. The left atrial auricle lesion created a massive hemorrhage during chest closure due to contact with the staplers of the left pulmonary artery stapler line. The hemorrhaging was stopped immediately. The patient has entirely recovered one year after surgery, and no adverse events or relapses have occurred.","PeriodicalId":500149,"journal":{"name":"Chest disease reports","volume":"40 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134905703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Georgi Yankov, Magdalena Aleksieva, Asen Keltchev, Evgeni Mekov
Inflammatory Myofibroblastic Tumor (IMT) is a benign tumor that is extremely rare. We present a 54-year-old man who has received 23 years of conservative treatment for IMT, respiratory infections, aspergillosis, and hemoptysis. A left intrapericardial pneumonectomy was performed with efficacy. The left atrial auricle lesion created a massive hemorrhage during chest closure due to contact with the staplers of the left pulmonary artery stapler line. The hemorrhaging was stopped immediately. The patient has entirely recovered one year after surgery, and no adverse events or relapses have occurred.
{"title":"Central lung inflammatory myofibroblastic tumor after aspergillosis and total occlusion of the left pulmonary artery","authors":"Georgi Yankov, Magdalena Aleksieva, Asen Keltchev, Evgeni Mekov","doi":"10.4081/cdr.11.11957","DOIUrl":"https://doi.org/10.4081/cdr.11.11957","url":null,"abstract":"Inflammatory Myofibroblastic Tumor (IMT) is a benign tumor that is extremely rare. We present a 54-year-old man who has received 23 years of conservative treatment for IMT, respiratory infections, aspergillosis, and hemoptysis. A left intrapericardial pneumonectomy was performed with efficacy. The left atrial auricle lesion created a massive hemorrhage during chest closure due to contact with the staplers of the left pulmonary artery stapler line. The hemorrhaging was stopped immediately. The patient has entirely recovered one year after surgery, and no adverse events or relapses have occurred.","PeriodicalId":500149,"journal":{"name":"Chest disease reports","volume":"6 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134905971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Georgi Yankov, Magdalena Aleksieva, Asen Keltchev, Evgeni Mekov
Inflammatory Myofibroblastic Tumor (IMT) is an exceptionally uncommon benign tumor. We present a 54-year-old man with IMT, frequent episodes of respiratory infections, aspergillosis, and hemoptysis, who has received 23 years of conservative treatment. A successful left intrapericardial pneumonectomy was performed. During chest closure, the left atrial auricle lesion caused a massive hemorrhage owing to contact with the staplers of the left pulmonary artery stapler line. The bleeding was immediately controlled. One year after surgery, the patient has fully recovered and no adverse events or relapses have occurred.
{"title":"Central lung Inflammatory Myofibroblastic Tumor after aspergillosis and total occlusion of the left pulmonary artery","authors":"Georgi Yankov, Magdalena Aleksieva, Asen Keltchev, Evgeni Mekov","doi":"10.4081/cdr.2023.11957","DOIUrl":"https://doi.org/10.4081/cdr.2023.11957","url":null,"abstract":"Inflammatory Myofibroblastic Tumor (IMT) is an exceptionally uncommon benign tumor. We present a 54-year-old man with IMT, frequent episodes of respiratory infections, aspergillosis, and hemoptysis, who has received 23 years of conservative treatment. A successful left intrapericardial pneumonectomy was performed. During chest closure, the left atrial auricle lesion caused a massive hemorrhage owing to contact with the staplers of the left pulmonary artery stapler line. The bleeding was immediately controlled. One year after surgery, the patient has fully recovered and no adverse events or relapses have occurred.","PeriodicalId":500149,"journal":{"name":"Chest disease reports","volume":"21 9","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134908930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Intestinal adenocarcinoma spontaneously developing in an anterior mediastinal multilocular teratoma in a 33-year-old female is described. The patient has been experiencing chest distress for several months. On a chest X-ray, a cystic anterior mediastinal mass was identified. A subsequent computed tomography scan revealed a heterogeneous mass measuring 20x15x10 centimeters in the anterior right mediastinum. She underwent a median thoracotomy excision. The histopathologic examination revealed a mature teratoma with intestinal adenocarcinoma metastases associated with pulmonary, cutaneous, and diaphragmatic metastases.
{"title":"Metastatic intestinal adenocarcinoma arising within mature teratoma of the mediastinum: report of a surgically-resected case","authors":"Yoldez Houcine, Chirine Moussa, Tarek Abid, Sadok Hammami, Héla Skhiri, Aida Ayadi","doi":"10.4081/cdr.2023.11840","DOIUrl":"https://doi.org/10.4081/cdr.2023.11840","url":null,"abstract":"Intestinal adenocarcinoma spontaneously developing in an anterior mediastinal multilocular teratoma in a 33-year-old female is described. The patient has been experiencing chest distress for several months. On a chest X-ray, a cystic anterior mediastinal mass was identified. A subsequent computed tomography scan revealed a heterogeneous mass measuring 20x15x10 centimeters in the anterior right mediastinum. She underwent a median thoracotomy excision. The histopathologic examination revealed a mature teratoma with intestinal adenocarcinoma metastases associated with pulmonary, cutaneous, and diaphragmatic metastases.","PeriodicalId":500149,"journal":{"name":"Chest disease reports","volume":"2 7","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135218511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Intestinal adenocarcinoma spontaneously developing in an anterior mediastinal multilocular teratoma in a 33-year-old female is described. The patient has been experiencing chest distress for several months. On a chest X-ray, a cystic anterior mediastinal mass was identified. A subsequent computed tomography scan revealed a heterogeneous mass measuring 20x15x10 centimeters in the anterior right mediastinum. She underwent a median thoracotomy excision. The histopathologic examination revealed a mature teratoma with intestinal adenocarcinoma metastases associated with pulmonary, cutaneous, and diaphragmatic metastases.
{"title":"Metastatic intestinal adenocarcinoma arising within mature teratoma of the mediastinum: report of a surgically-resected case","authors":"Yoldez Houcine, Chirine Moussa, Tarek Abid, Sadok Hammami, Héla Skhiri, Aida Ayadi","doi":"10.4081/cdr.11.11840","DOIUrl":"https://doi.org/10.4081/cdr.11.11840","url":null,"abstract":"Intestinal adenocarcinoma spontaneously developing in an anterior mediastinal multilocular teratoma in a 33-year-old female is described. The patient has been experiencing chest distress for several months. On a chest X-ray, a cystic anterior mediastinal mass was identified. A subsequent computed tomography scan revealed a heterogeneous mass measuring 20x15x10 centimeters in the anterior right mediastinum. She underwent a median thoracotomy excision. The histopathologic examination revealed a mature teratoma with intestinal adenocarcinoma metastases associated with pulmonary, cutaneous, and diaphragmatic metastases.","PeriodicalId":500149,"journal":{"name":"Chest disease reports","volume":"5 9","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135167500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A male individual, aged 54, exhibited symptoms including fever, rigors, myalgia, dry cough, and dyspnea. Ten days prior, he provided a description of an ailment resembling an upper respiratory infection. The recorded body temperature measured 38.2⁰C. The physical examination findings included the presence of scleral icterus, jaundice, conjunctival hyperemia, extensive ecchymoses at multiple locations on the body, an antecubital hematoma, bilateral basal rales, hepatomegaly, and splenomegaly. The White Blood Cell Count (WBC) was measured to be 1.100/mm3, Hemoglobin (Hgb) level was found to be 11.8 g/dL, the platelet count was seen to be 10.000/mm3,
{"title":"A diagnosis of leptospirosis: a case report","authors":"Cuneyt Tetikkurt, Halil Yanardag, Muammer Bilir","doi":"10.4081/cdr.2023.11684","DOIUrl":"https://doi.org/10.4081/cdr.2023.11684","url":null,"abstract":"A male individual, aged 54, exhibited symptoms including fever, rigors, myalgia, dry cough, and dyspnea. Ten days prior, he provided a description of an ailment resembling an upper respiratory infection. The recorded body temperature measured 38.2⁰C. The physical examination findings included the presence of scleral icterus, jaundice, conjunctival hyperemia, extensive ecchymoses at multiple locations on the body, an antecubital hematoma, bilateral basal rales, hepatomegaly, and splenomegaly. The White Blood Cell Count (WBC) was measured to be 1.100/mm3, Hemoglobin (Hgb) level was found to be 11.8 g/dL, the platelet count was seen to be 10.000/mm3,","PeriodicalId":500149,"journal":{"name":"Chest disease reports","volume":"3 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135216040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A 54-year-old male presented with symptoms of fever, rigors, myalgia, dry cough, and dyspnea. Ten days earlier, he described a condition resembling an upper respiratory infection. The measured body temperature was 38.20°C. Scleral icterus, jaundice, conjunctival hyperemia, extensive ecchymoses at multiple sites on the body, an antecubital hematoma, bilateral basal rales, hepatomegaly, and splenomegaly were observed during the physical examination. The White Blood Cell Count (WBC) was determined to be 1,100/mm3, the Hemoglobin (Hgb) level was 11.8 g/dL, and the platelet count was 10,000/mm3.
{"title":"A diagnosis of leptospirosis: a case report","authors":"Cuneyt Tetikkurt, Halil Yanardag, Muammer Bilir","doi":"10.4081/cdr.11.11684","DOIUrl":"https://doi.org/10.4081/cdr.11.11684","url":null,"abstract":"A 54-year-old male presented with symptoms of fever, rigors, myalgia, dry cough, and dyspnea. Ten days earlier, he described a condition resembling an upper respiratory infection. The measured body temperature was 38.20°C. Scleral icterus, jaundice, conjunctival hyperemia, extensive ecchymoses at multiple sites on the body, an antecubital hematoma, bilateral basal rales, hepatomegaly, and splenomegaly were observed during the physical examination. The White Blood Cell Count (WBC) was determined to be 1,100/mm3, the Hemoglobin (Hgb) level was 11.8 g/dL, and the platelet count was 10,000/mm3.","PeriodicalId":500149,"journal":{"name":"Chest disease reports","volume":"12 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135167495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respiratory failure occurs in 0.1-0.2% of pregnancy patients. This can be due to pre-eclampsia, venous thromboembolism, asthma, gastric aspiration, and viral pneumonitis. Rarely exacerbation of underlying diseases (like asthma, Interstitial Lung Disease, ILD, etc.) can cause respiratory failure. The underlying disease can be recognized previously or presented as exacerbation in pregnancy for the first time. Respiratory failure leads to harm to both mother and fetus; hence, the cause should be evaluated as soon as possible. Here, we are describing the case of acute exacerbation of Hypersensitivity Pneumonitis (HP) in a pre-eclampsia patient.
{"title":"A rare cause of respiratory failure in pregnancy - acute exacerbation of undiagnosed hypersensitivity pneumonitis mimicking complication of severe preeclampsia","authors":"Arpitha Anantharaju, Pratap Upadhya, Sivaselvi C., Ashwini Raj, Vishnukath Govindaraj, Gowri Dorairajan","doi":"10.4081/cdr.11.11889","DOIUrl":"https://doi.org/10.4081/cdr.11.11889","url":null,"abstract":"Respiratory failure occurs in 0.1-0.2% of pregnancy patients. This can be due to pre-eclampsia, venous thromboembolism, asthma, gastric aspiration, and viral pneumonitis. Rarely exacerbation of underlying diseases (like asthma, Interstitial Lung Disease, ILD, etc.) can cause respiratory failure. The underlying disease can be recognized previously or presented as exacerbation in pregnancy for the first time. Respiratory failure leads to harm to both mother and fetus; hence, the cause should be evaluated as soon as possible. Here, we are describing the case of acute exacerbation of Hypersensitivity Pneumonitis (HP) in a pre-eclampsia patient.","PeriodicalId":500149,"journal":{"name":"Chest disease reports","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135665709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Respiratory failure occurs in 0.1-0.2% of pregnancy patients. This can be due to pre-eclampsia, venous thromboembolism, asthma, gastric aspiration, and viral pneumonitis. Rarely exacerbation of underlying diseases (like asthma, Interstitial Lung Disease, ILD, etc.) can cause respiratory failure. The underlying disease can be recognized previously or presented as exacerbation in pregnancy for the first time. Respiratory failure leads to harm to both mother and fetus; hence, the cause should be evaluated as soon as possible. Here, we are describing the case of acute exacerbation of Hypersensitivity Pneumonitis (HP) in a pre-eclampsia patient.
{"title":"A rare cause of respiratory failure in pregnancy - acute exacerbation of undiagnosed Hypersensitivity Pneumonitis mimicking complication of severe preeclampsia","authors":"Arpitha Anantharaju, Pratap Upadhya, Sivaselvi C., Ashwini Raj, Vishnukath Govindaraj, Gowri Dorairajan","doi":"10.4081/cdr.2023.11889","DOIUrl":"https://doi.org/10.4081/cdr.2023.11889","url":null,"abstract":"Respiratory failure occurs in 0.1-0.2% of pregnancy patients. This can be due to pre-eclampsia, venous thromboembolism, asthma, gastric aspiration, and viral pneumonitis. Rarely exacerbation of underlying diseases (like asthma, Interstitial Lung Disease, ILD, etc.) can cause respiratory failure. The underlying disease can be recognized previously or presented as exacerbation in pregnancy for the first time. Respiratory failure leads to harm to both mother and fetus; hence, the cause should be evaluated as soon as possible. Here, we are describing the case of acute exacerbation of Hypersensitivity Pneumonitis (HP) in a pre-eclampsia patient.","PeriodicalId":500149,"journal":{"name":"Chest disease reports","volume":"123 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135569476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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