Pub Date : 2024-05-24DOI: 10.1088/2752-5724/ad47ce
Jingbo Li, Yile Fang, Zhuhao Wu, Luoran Shang, Ling Li
Islet transplantation is a promising strategy for diabetes mellitus treatment as it can recapitulate endogenous insulin secretion and provide long-term glycemic control. Islet models constructed in biomaterial scaffolds that reproduce biological characteristics of native islets is a feasible option to circumvent the dilemma of donor shortage and the requirement of chronic immunosuppression. Herein, we developed bioinspired artificial microcapsule-based islet models with microvessels for glycemic control using microfluidic electrospray strategy. Microfluidic electrospray can generate uniform hydrogel microcapsules with core-shell structure for encapsulating islet cells. The cell-laden microcapsules enabled the efficient transportation of nutrient, oxygen, and insulin; as well as the incorporation with microvessels for prompting glucose responsiveness and molecular exchange. We demonstrated by in vivo experiments that the blood glucose, food intake, and body weight of diabetic mouse models were alleviated, and the glucose tolerance was promoted after the engraftment of islet microcapsules. We further demonstrated the improved functionality of transplanted islet model in insulin secretion, immune escape, and microcirculation using standard histological and molecular analysis. These results indicated that the microcapsules with microvessels are promising artificial islet models and are valuable for treating diabetes.
{"title":"Biomimetic artificial islet model with vascularized microcapsule structures for durable glycemic control","authors":"Jingbo Li, Yile Fang, Zhuhao Wu, Luoran Shang, Ling Li","doi":"10.1088/2752-5724/ad47ce","DOIUrl":"https://doi.org/10.1088/2752-5724/ad47ce","url":null,"abstract":"\u0000 Islet transplantation is a promising strategy for diabetes mellitus treatment as it can recapitulate endogenous insulin secretion and provide long-term glycemic control. Islet models constructed in biomaterial scaffolds that reproduce biological characteristics of native islets is a feasible option to circumvent the dilemma of donor shortage and the requirement of chronic immunosuppression. Herein, we developed bioinspired artificial microcapsule-based islet models with microvessels for glycemic control using microfluidic electrospray strategy. Microfluidic electrospray can generate uniform hydrogel microcapsules with core-shell structure for encapsulating islet cells. The cell-laden microcapsules enabled the efficient transportation of nutrient, oxygen, and insulin; as well as the incorporation with microvessels for prompting glucose responsiveness and molecular exchange. We demonstrated by in vivo experiments that the blood glucose, food intake, and body weight of diabetic mouse models were alleviated, and the glucose tolerance was promoted after the engraftment of islet microcapsules. We further demonstrated the improved functionality of transplanted islet model in insulin secretion, immune escape, and microcirculation using standard histological and molecular analysis. These results indicated that the microcapsules with microvessels are promising artificial islet models and are valuable for treating diabetes.","PeriodicalId":500817,"journal":{"name":"Materials futures","volume":"7 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141100230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Perovskite (PVK) solar cells (PSCs) have garnered considerable research interest owing to their cost-effectiveness and high efficiency. A systematic annual review of the research on PSCs is essential for gaining a comprehensive understanding of the current research trends. Herein, systematic analysis of the research papers on PSCs reporting key findings in 2023 was conducted. Based on the results, the papers were categorized into six classifications, including regular n-i-p PSCs, inverted p-i-n PSCs, PVK-based tandem solar cells, PVK solar modules, device stability, and lead toxicity and green solvents. Subsequently, a detailed overview and summary of the annual research advancements within each classification were presented. Overall, this review serves as a valuable resource for guiding future research endeavors in the field of PSCs.
{"title":"Annual Research Review of Perovskite Solar Cells in 2023","authors":"Qisen Zhou, Xiaoxuan Liu, Zonghao Liu, Yanqing Zhu, Jianfeng Lu, Ziming Chen, Canjie Li, Jing Wang, Qifan Xue, Feifei He, Jia Liang, Hongyu Li, Shenghao Wang, Qidong Tai, Yiqiang Zhang, Jiehua Liu, Chuantian Zuo, Liming Ding, Zhenghong Xiong, Renhao Zheng, Huimin Zhang, Pengjun Zhao, Xi Jin, Peng Wu, Fei Zhang, Yan Jiang, Huanping Zhou, Jinsong Hu, Yang Wang, Yanlin Song, Yaohua Mai, Baomin Xu, Shengzhong Liu, Liyuan Han, Wei Chen","doi":"10.1088/2752-5724/ad42ba","DOIUrl":"https://doi.org/10.1088/2752-5724/ad42ba","url":null,"abstract":"\u0000 Perovskite (PVK) solar cells (PSCs) have garnered considerable research interest owing to their cost-effectiveness and high efficiency. A systematic annual review of the research on PSCs is essential for gaining a comprehensive understanding of the current research trends. Herein, systematic analysis of the research papers on PSCs reporting key findings in 2023 was conducted. Based on the results, the papers were categorized into six classifications, including regular n-i-p PSCs, inverted p-i-n PSCs, PVK-based tandem solar cells, PVK solar modules, device stability, and lead toxicity and green solvents. Subsequently, a detailed overview and summary of the annual research advancements within each classification were presented. Overall, this review serves as a valuable resource for guiding future research endeavors in the field of PSCs.","PeriodicalId":500817,"journal":{"name":"Materials futures","volume":"63 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140665889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-08DOI: 10.1088/2752-5724/ad3bd5
Huan Liu, Fei Yu, Bing Chen, Zhengdong Luo, Jiajia Chen, Yong Zhang, Ze Feng, Hong Dong, Xiao Yu, Yan Liu, Genquan Han, Yue Hao
Ferroelectric HfO2-based materials and devices show promising potential for advancing emerging information technology but face challenges with inadequate electrostatic control, degraded reliability, and serious variation for EOT (effective oxide thickness) scaling. We demonstrate a novel interface-type switching strategy to realize ferroelectric characteristics in atomic-scale amorphous binary oxide films, which are formed in oxygen-deficient conditions by atomic layer deposition (ALD) at low temperatures. This approach can avoid the shortcomings of reliability degradation and gate leakage increment in scaling poly-crystalline doped HfO2-based films. Through theoretical modeling and experimental characterization, we show that: 1) Emerging ferroelectricity exists in the ultrathin oxide system due to microscopic ion migration in the switching process. 2) These ferroelectric binary oxide films are governed by the interface-limited switching mechanism, which can be attributed to the oxygen vacancy migration and the surface defect related to electron (de)trapping. 3) Transistors featuring ultrathin amorphous dielectrics, used for nonvolatile memory applications with an operating voltage reduced to ±1 V, have also been experimentally demonstrated. These findings suggest that the strategy is a promising approach to realizing the next-generation CMOS with scalable ferroelectric material.
{"title":"Evidence for reversible oxygen ion movement during electrical pulsing: enabler of the emerging ferroelectricity in binary oxides","authors":"Huan Liu, Fei Yu, Bing Chen, Zhengdong Luo, Jiajia Chen, Yong Zhang, Ze Feng, Hong Dong, Xiao Yu, Yan Liu, Genquan Han, Yue Hao","doi":"10.1088/2752-5724/ad3bd5","DOIUrl":"https://doi.org/10.1088/2752-5724/ad3bd5","url":null,"abstract":"\u0000 Ferroelectric HfO2-based materials and devices show promising potential for advancing emerging information technology but face challenges with inadequate electrostatic control, degraded reliability, and serious variation for EOT (effective oxide thickness) scaling. We demonstrate a novel interface-type switching strategy to realize ferroelectric characteristics in atomic-scale amorphous binary oxide films, which are formed in oxygen-deficient conditions by atomic layer deposition (ALD) at low temperatures. This approach can avoid the shortcomings of reliability degradation and gate leakage increment in scaling poly-crystalline doped HfO2-based films. Through theoretical modeling and experimental characterization, we show that: 1) Emerging ferroelectricity exists in the ultrathin oxide system due to microscopic ion migration in the switching process. 2) These ferroelectric binary oxide films are governed by the interface-limited switching mechanism, which can be attributed to the oxygen vacancy migration and the surface defect related to electron (de)trapping. 3) Transistors featuring ultrathin amorphous dielectrics, used for nonvolatile memory applications with an operating voltage reduced to ±1 V, have also been experimentally demonstrated. These findings suggest that the strategy is a promising approach to realizing the next-generation CMOS with scalable ferroelectric material.","PeriodicalId":500817,"journal":{"name":"Materials futures","volume":"146 S281","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140731321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The performance of red InP and blue ZnTeSe-based quantum dots (QDs) and corresponding QD light emitting diodes (QLEDs) has already been improved significantly, whose external quantum efficiencies (EQEs) and luminances have exceeded 20% and 80,000 cd m-2, respectively. However, the inferior performance of the green InP-based device hinders the commercialization of full-color Cd-free QLED technology. The ease of oxidation of the highly reactive InP cores leads to high non-radiative recombination and poor photoluminescence quantum yield (PL QY) of the InP-based core/shell quantum dots (QDs), limiting the performance of the relevant QLEDs. Here, we proposed a fluoride-free synthesis strategy to in-situ passivate the InP cores, in which zinc myristate reacted with phosphine dangling bonds to form Zn-P protective layer and protect InP cores from the water and oxygen in the environment. The resultant InP/ZnSe/ZnS core/shell QDs demonstrated a high PL QY of 91%. The corresponding green-emitting electroluminescence devices exhibited a maximum EQE of 12.74%, along with a luminance of over 175,000 cd m-2 and a long T50@100 cd m-2 lifetime of over 20,000 h.
{"title":"High-brightness green InP-based QLEDs enabled by in-situ passivating core surface with zinc myristate","authors":"Yuanbin Cheng, Qian Li, Mengyuan Chen, Fei Chen, Zhenghui Wu, Huaibin Shen","doi":"10.1088/2752-5724/ad3a83","DOIUrl":"https://doi.org/10.1088/2752-5724/ad3a83","url":null,"abstract":"\u0000 The performance of red InP and blue ZnTeSe-based quantum dots (QDs) and corresponding QD light emitting diodes (QLEDs) has already been improved significantly, whose external quantum efficiencies (EQEs) and luminances have exceeded 20% and 80,000 cd m-2, respectively. However, the inferior performance of the green InP-based device hinders the commercialization of full-color Cd-free QLED technology. The ease of oxidation of the highly reactive InP cores leads to high non-radiative recombination and poor photoluminescence quantum yield (PL QY) of the InP-based core/shell quantum dots (QDs), limiting the performance of the relevant QLEDs. Here, we proposed a fluoride-free synthesis strategy to in-situ passivate the InP cores, in which zinc myristate reacted with phosphine dangling bonds to form Zn-P protective layer and protect InP cores from the water and oxygen in the environment. The resultant InP/ZnSe/ZnS core/shell QDs demonstrated a high PL QY of 91%. The corresponding green-emitting electroluminescence devices exhibited a maximum EQE of 12.74%, along with a luminance of over 175,000 cd m-2 and a long T50@100 cd m-2 lifetime of over 20,000 h.","PeriodicalId":500817,"journal":{"name":"Materials futures","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140742847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-03-06DOI: 10.1088/2752-5724/ad305e
Huijun Kong, Weiyan Li, Zhongqian Song, Li Niu
Human skin perceives external environmental stimulus by the synergies between the subcutaneous tactile corpuscles. Soft electronics with multiple sensing capabilities by mimicking the function of human skin are of significance in health monitoring and artificial sensation. The last decade has witnessed unprecedented development and convergence between multimodal tactile sensing devices and soft bioelectronics. Despite these advances, traditional flexible electronics achieve multimodal tactile sensing for pressure, strain, temperature, and humidity by integrating monomodal sensing devices together. This strategy results in high energy consumption, limited integration, and complex manufacturing process. Various multimodal sensors and crosstalk-free sensing mechanisms have been proposed to bridge the gap between natural sensory system and artificial perceptual system. In this review, we provide a comprehensive summary of tactile sensing mechanism, integration design principles, signal-decoupling strategies, and current applications for multimodal tactile perception. Finally, we highlight the current challenges and present the future perspectives to promote the development of multimodal tactile perception.
{"title":"Recent advances in multimodal sensing integration and decoupling strategies for tactile perception","authors":"Huijun Kong, Weiyan Li, Zhongqian Song, Li Niu","doi":"10.1088/2752-5724/ad305e","DOIUrl":"https://doi.org/10.1088/2752-5724/ad305e","url":null,"abstract":"\u0000 Human skin perceives external environmental stimulus by the synergies between the subcutaneous tactile corpuscles. Soft electronics with multiple sensing capabilities by mimicking the function of human skin are of significance in health monitoring and artificial sensation. The last decade has witnessed unprecedented development and convergence between multimodal tactile sensing devices and soft bioelectronics. Despite these advances, traditional flexible electronics achieve multimodal tactile sensing for pressure, strain, temperature, and humidity by integrating monomodal sensing devices together. This strategy results in high energy consumption, limited integration, and complex manufacturing process. Various multimodal sensors and crosstalk-free sensing mechanisms have been proposed to bridge the gap between natural sensory system and artificial perceptual system. In this review, we provide a comprehensive summary of tactile sensing mechanism, integration design principles, signal-decoupling strategies, and current applications for multimodal tactile perception. Finally, we highlight the current challenges and present the future perspectives to promote the development of multimodal tactile perception.","PeriodicalId":500817,"journal":{"name":"Materials futures","volume":"14 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140263239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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