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Duration of anaesthesia, type of surgery, respiratory co-morbidity, predicted VO2max and smoking predict postoperative pulmonary complications after upper abdominal surgery: an observational study 麻醉时间、手术类型、呼吸合并症、预测VO2max和吸烟预测上腹部手术后肺部并发症:一项观察性研究
Pub Date : 2009-01-01 DOI: 10.1016/S0004-9514(09)70081-9
Rebecca L. Scholes , Laura Browning , Ewa M. Sztendur , Linda Denehy

Question

Can the risk of developing postoperative pulmonary complications be predicted after upper abdominal surgery?

Design

Prospective observational study.

Participants

268 consecutive patients undergoing elective upper abdominal surgery who received standardised pre- and postoperative prophylactic respiratory physiotherapy.

Outcome measures

Predictors were 17 preoperative and intraoperative risk factors. A postoperative pulmonary complication was diagnosed when four or more of the following criteria were present: radiological evidence of collapse/consolidation, temperature > 38°C, oxyhaemoglobin saturation < 90%, abnormal sputum production, sputum culture indicating infection, raised white cell count, abnormal auscultation findings, or physician's diagnosis of pulmonary complication.

Results

35 participants (13%) developed postoperative pulmonary complications. Five risk factors predicted postoperative pulmonary complications: duration of anaesthesia (OR 4.3, 95% CI 1.7 to 10.8); surgical category (OR 2.3, 95% CI 1.1 to 4.7); current smoking (OR 2.1, 95% CI 1.0 to 4.5); respiratory co-morbidity (OR 2.1, 95% CI 1.0 to 4.4); and predicted maximal oxygen uptake (OR 2.0, 95% CI 1.0 to 4.3). A clinical rule for predicting the development of postoperative pulmonary complications predicted 82% of participants who developed complications. The odds of high risk participants developing pulmonary complications were 8.4 (95% CI 3.3 to 21.3) times that of low risk participants.

Conclusion

This clinical rule for predicting the risk of developing postoperative pulmonary complications from five risk factors may prove useful in prioritising postoperative respiratory physiotherapy. Further research is needed to validate the rule.

问题:能否预测上腹部手术后发生术后肺部并发症的风险?前瞻性观察性研究。参与者:268例连续接受择期上腹部手术的患者,接受标准化的术前和术后预防性呼吸物理治疗。预后指标为17个术前和术中危险因素。当出现以下四项或以上标准时,诊断为术后肺部并发症:影像学证据显示塌陷/实变,温度和gt;38°C,氧合血红蛋白饱和度;90%,痰量异常,痰培养提示感染,白细胞计数升高,听诊异常,或医生诊断为肺部并发症。结果35例(13%)患者出现术后肺部并发症。预测术后肺部并发症的5个危险因素:麻醉时间(OR 4.3, 95% CI 1.7 ~ 10.8);外科分类(OR 2.3, 95% CI 1.1 ~ 4.7);目前吸烟(OR 2.1, 95% CI 1.0 - 4.5);呼吸道合并症(OR 2.1, 95% CI 1.0 ~ 4.4);并预测最大摄氧量(OR 2.0, 95% CI 1.0 ~ 4.3)。一项预测术后肺部并发症发生的临床规则预测了82%的参与者出现并发症。高风险参与者发生肺部并发症的几率是低风险参与者的8.4倍(95% CI 3.3 ~ 21.3)。结论从5个危险因素预测术后肺部并发症发生风险的临床规律,可用于确定术后呼吸物理治疗的优先级。需要进一步的研究来验证这一规则。
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引用次数: 89
Aerobic exercise improves lung function in children with intellectual disability: a randomised trial 有氧运动改善智障儿童肺功能:一项随机试验
Pub Date : 2009-01-01 DOI: 10.1016/S0004-9514(09)70077-7
Mohammad A. Khalili , Mark R. Elkins

Question

In children with intellectual disability, is lung function lower than in healthy peers and does it improve with exercise?

Design

Randomised trial with intention-to-treat analysis and assessor blinding.

Participants

Forty-four 12-year old children with Down syndrome or other intellectual disability with an average IQ of 42 (SD 8).

Intervention

The experimental group performed aerobic exercise for 30 minutes, five days per week, for eight weeks. The exercise was supervised walking, running, and cycling, with a target of moderate intensity. The control group continued usual activities and performed no specific exercise.

Outcome measures

Lung function as FEV1 and FVC in litres was measured with spirometry at baseline and after the intervention at eight weeks. Prior to the baseline measures, all participants underwent familiarisation of spirometry for one week.

Results

At baseline, FEV1 of the children with intellectual disability was a mean of 87% (95% CI 83 to 91) and FVC was 94% (95% CI 91 to 97) of predicted normal values. After intervention, FEV1 had increased by 160 ml (95% CI 30 to 290) and FVC by 330 ml (95% CI 200 to 460) more in the experimental group than the control group.

Conclusion

An 8-week program of aerobic exercise improves lung function in children with intellectual disability significantly.

智力残疾儿童的肺功能是否比健康儿童低,是否能通过锻炼得到改善?设计采用意向治疗分析和评估盲法的随机试验。参与者44名患有唐氏综合症或其他智力残疾的12岁儿童,平均智商为42 (SD 8)。干预实验组每周进行5天,每次30分钟的有氧运动,持续8周。这项运动包括散步、跑步和骑自行车,目标是中等强度。对照组继续进行常规活动,不进行特殊运动。结果测量:在基线和干预后8周用肺活量测定法测量肺功能FEV1和FVC(以升计)。在基线测量之前,所有参与者都进行了一周的肺活量测定熟悉。结果在基线时,智力残疾儿童的FEV1平均为预测正常值的87% (95% CI 83 ~ 91), FVC为预测正常值的94% (95% CI 91 ~ 97)。干预后,实验组FEV1比对照组增加160 ml (95% CI 30 ~ 290), FVC比对照组增加330 ml (95% CI 200 ~ 460)。结论为期8周的有氧运动可显著改善智力残疾儿童的肺功能。
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引用次数: 53
Progressive resistance exercise improves glycaemic control in people with type 2 diabetes mellitus: a systematic review 进行性抗阻运动改善2型糖尿病患者的血糖控制:一项系统综述
Pub Date : 2009-01-01 DOI: 10.1016/S0004-9514(09)70003-0
Casey Irvine , Nicholas F. Taylor

Question

Is progressive resistance exercise a safe and effective form of exercise to improve glycaemic control in people with type 2 diabetes?

Design

Systematic review with meta-analysis of randomised controlled trials.

Participants

People with type 2 diabetes mellitus.

Intervention

Progressive resistance exercise.

Outcome measures

The primary outcome was glycaemic control measured as percentage glycosylated haemoglobin (HbA1c). Secondary outcomes were body composition (lean body and fat free mass in kg), and muscle strength (% change in 1RM, dynamometry, change in maximum weight lifted).

Results

The search yielded nine relevant trials that evaluated 372 people with type 2 diabetes. Compared to not exercising, progressive resistance exercise led to small and statistically significant absolute reductions in HbA1c of 0.3% (SMD –0.25, 95% CI –0.47 to –0.03). When compared to aerobic exercise there were no significant differences in HbA1c. Progressive resistance exercise resulted in large improvements in strength when compared to aerobic (SMD 1.44, 95% CI 0.83 to 2.05) or no exercise (SMD 0.95, 95% CI 0.58 to 1.31). There were no significant changes in body composition.

Conclusions

Progressive resistance exercise increases strength and leads to small reductions in glycosylated haemoglobin that are likely to be clinically significant for people with type 2 diabetes. Progressive resistance exercise is a feasible option in the management of glycaemia for this population.

渐进式抵抗运动是一种安全有效的改善2型糖尿病患者血糖控制的运动形式吗?设计采用随机对照试验的荟萃分析进行系统评价。参与者为2型糖尿病患者。干预:进行性抗阻运动。主要终点是血糖控制,以糖化血红蛋白百分比(HbA1c)衡量。次要结果是身体组成(以kg为单位的瘦体和无脂肪质量)和肌肉力量(1RM变化百分比、动力测量、最大举起重量变化)。研究人员对372名2型糖尿病患者进行了9项相关试验。与不运动相比,渐进式阻力运动导致HbA1c绝对降低0.3% (SMD -0.25, 95% CI -0.47至-0.03)。与有氧运动相比,HbA1c无显著差异。与有氧运动(SMD = 1.44, 95% CI = 0.83 - 2.05)或不运动(SMD = 0.95, 95% CI = 0.58 - 1.31)相比,渐进式阻力运动显著改善了力量。身体成分没有明显变化。进行性阻力运动增加力量,导致糖化血红蛋白的少量减少,这对2型糖尿病患者可能具有临床意义。进行性抗阻运动是这一人群血糖管理的可行选择。
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引用次数: 116
Global Rating of Change scales 全球变化评级量表
Pub Date : 2009-01-01 DOI: 10.1016/S0004-9514(09)70015-7
Steve Kamper
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引用次数: 63
Quality of trials in Australian Journal of Physiotherapy 澳大利亚物理治疗杂志的试验质量
Pub Date : 2009-01-01 DOI: 10.1016/S0004-9514(09)70001-7
Mark Elkins , Louise Ada
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引用次数: 1
Cincinnati Orthopaedic Disability Index in canines 犬科动物辛辛那提骨科残疾指数
Pub Date : 2009-01-01 DOI: 10.1016/S0004-9514(09)70014-5
Stephanie Valentin
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引用次数: 5
Lumbar spinal stenosis 腰椎管狭窄
Pub Date : 2009-01-01 DOI: 10.1016/S0004-9514(09)70068-6
Sandra Brauer
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引用次数: 0
Electrical stimulation is a useful adjunct in the management of urinary incontinence in people with multiple sclerosis 电刺激是治疗多发性硬化症患者尿失禁的有效辅助手段
Pub Date : 2009-01-01 DOI: 10.1016/S0004-9514(09)70063-7
Eleanor Lee-Bognar

Question

Does neuromuscular electrical stimulation improve lower urinary tract dysfunction in people with multiple sclerosis (MS), when given in addition to pelvic floor exercises and electromyographic biofeedback?

Design

Randomised, controlled trial with concealed allocation and blinded assessment of some outcomes.

Setting

Twelve health-care facilities in Northern Ireland.

Participants

Adults with MS with no hospital admissions in the preceding 3 months. They were required to have lower urinary tract dysfunction (involuntary leakage, > 8 voids per day, nocturia, or voiding dysfunction) but not to score more than 7.5 on the Expanded Disability Status Scale (EDSS) from 0 (normal) to 10 (death due to MS). Symptomatic prolapse, prostatic hyperplasia, infection and contraindications to electrical stimulation were exclusion criteria. Randomisation of 74 participants allotted 37 to each of two groups.

Interventions

Both groups were taught skills and strategies to prevent incontinence and trained in pelvic floor muscle exercises. Both groups were taught to perform the exercises with electrical stimulation via a hand-held unit with a vaginal or anal probe. The treatment group received active stimulation while the control group received sham stimulation. Both groups performed the exercises daily for 9 weeks. The exercises were reviewed with electromyographic biofeedback at a weekly clinic visit.

Outcome measures

The primary outcome was the number of leakage episodes per day as monitored by diary. Secondary outcome measures included gain in pad weight after use, voiding measures, symptom questionnaires, and assessment of pelvic floor muscle function using the Oxford classification and EMG. All outcomes were measured at 9, 16, and 24 weeks.

Results

In each group, 36 participants completed the study. At 9 weeks, the treatment group had significantly less incontinence, with 0.8 fewer episodes per day (95% CI 0.1 to 1.4) and 89 g lighter pads (95% CI 8 to 171) than the control group. The treatment group also had significantly larger voids, by 47 ml (95% CI 1 to 93), and significantly smaller post-void residual volumes. Symptoms were also rated as significantly less bothersome. At 24 weeks, however, pad weight was the only objective outcome that remained statistically significant. Nevertheless, patients in the treatment group still rated their symptoms as significantly less bothersome on two questionnaires.

Conclusion

For people with MS, the addition of electrical stimulation to a program of pelvic floor muscle training and EMG biofeedback induces several improvements in lower urinary tract dysfunction. Although some improvements were temporary, symptoms remained less bothersome for 24 weeks.

神经肌肉电刺激是否能改善多发性硬化症(MS)患者的下尿路功能障碍,在盆底运动和肌电生物反馈的基础上进行?随机对照试验,隐匿分配,对部分结果进行盲法评估。在北爱尔兰设立了12个保健设施。参与者:前3个月内未住院的成年MS患者。他们被要求有下尿路功能障碍(不自主渗漏,>每天排空8次,夜尿症或排尿功能障碍),但在扩展残疾状态量表(EDSS)中得分不超过7.5分,从0分(正常)到10分(死于多发性硬化症)。排除标准为症状性脱垂、前列腺增生、感染和电刺激禁忌症。74名参与者随机分为两组,每组37人。干预措施:两组患者均接受了预防尿失禁的技巧和策略培训,并进行了盆底肌肉锻炼。两组人都被教导通过带有阴道或肛门探针的手持装置进行电刺激练习。治疗组采用主动刺激,对照组采用假刺激。两组每天都进行锻炼,持续9周。在每周一次的诊所访问中,用肌电图生物反馈来评估这些练习。主要结果是通过日记监测每天的渗漏次数。次要结果测量包括使用后尿垫重量增加、排尿测量、症状问卷调查以及使用牛津分类和肌电图评估盆底肌功能。在第9周、第16周和第24周测量所有结果。结果每组36人完成研究。在第9周时,治疗组的尿失禁明显减少,每天少0.8次(95% CI 0.1至1.4),尿垫轻89 g (95% CI 8至171)。治疗组的空腔也明显增大,增加了47 ml (95% CI 1 ~ 93),空腔后残留体积也明显减小。症状也被评为明显不那么麻烦。然而,在24周时,尿垫重量是唯一具有统计学意义的客观结果。然而,在两份调查问卷中,治疗组的患者仍然认为他们的症状明显不那么麻烦。结论:对于多发性硬化症患者,在盆底肌肉训练和肌电图生物反馈的基础上增加电刺激可改善下尿路功能障碍。虽然有些改善是暂时的,但症状在24周内仍然不那么麻烦。
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引用次数: 3
Endurance and strength training have different benefits for people with peripheral arterial disease, but both improve quality of life 耐力和力量训练对外周动脉疾病患者有不同的好处,但都能提高生活质量
Pub Date : 2009-01-01 DOI: 10.1016/S0004-9514(09)70064-9
Sandeep Gupta

Question

Do treadmill training and resistance training improve the functional performance of patients with peripheral arterial disease (PAD)?

Design

Randomised, controlled trial with blinded outcome assessment and stratification for symptoms of intermittent claudication (IC).

Setting

Tertiary hospital in the USA.

Participants

Participants with an ankle brachial index of 0.95 or less were recruited from vascular clinics and the community. Key exclusion criteria were critical limb ischaemia, foot ulcers, amputation, inability to attend or perform the interventions, and usual exercise comparable to the study regimens. Randomisation of 156 participants allotted 51 to treadmill training, 52 to resistance training and 53 to a control group.

Interventions

The treadmill group performed supervised treadmill exercise 3 times per week for 6 months. Participants aimed to increase to 40 minutes by week 8, after which the speed or grade of the treadmill was progressed. Participants with IC were encouraged to exercise to near maximal leg symptoms. Asymptomatic participants exercised at a perceived exertion of 12 to 14 on the Borg scale. The resistance group also performed supervised exercise 3 times per week for 6 months, including 3 sets of 8 repetitions of resisted lower limb exercises. External resistance was maintained above 50% of 1 repetition maximum and perceived exertion at 12 to 14. The control group attended 11 sessions that were designed to provide contact with a health professional but not to change behaviour.

Outcome measures

The primary outcomes were the change in the six-minute walk test (6MWT) and the short physical performance battery (SPPB) at 6 months. The SPPB assesses walking speed, balance, and sit-to-stand performance. Secondary outcome measures were treadmill endurance, lower limb strength, endothelial function measured non-invasively at the brachial artery, habitual physical activity measured over 7 days via an accelerometer, a walking impairment questionnaire (WIQ), and the SF-36 quality of life questionnaire.

Results

Compared to control, treadmill training significantly improved 6MW distance (by 36 m, 95% CI 15 to 57), total treadmill time (by 3.4 min, 95% CI 2 to 4.8), pain-free treadmill time (by 1.6 min, 95% CI 0.3 to 2.9), endothelial function, and the Distance domain of the WIQ. Compared to control, resistance training significantly improved total treadmill time (by 1.9 min, 95% CI 0.5 to 3.3), knee extension strength (by 80 N, 95% CI 37 to 124), and the Distance and Stair Climbing domains of the WIQ. Both regimens produced significant, 7.5-point improvements in the Physical Functioning domain of the SF-36.

Conclusion

Treadmill and resistance training have different benefits for people with peripheral arterial disease, but both improve qualit

跑步机训练和阻力训练能改善外周动脉疾病(PAD)患者的功能表现吗?随机对照试验,对间歇性跛行(IC)症状进行盲法结局评估和分层。美国三级医院。踝关节肱指数为0.95或更低的参与者从血管诊所和社区招募。主要排除标准为严重肢体缺血、足部溃疡、截肢、无法参加或执行干预措施以及与研究方案相当的日常运动。156名参与者随机分配,51人进行跑步机训练,52人进行阻力训练,53人作为对照组。干预措施:跑步机组每周进行3次有监督的跑步机锻炼,持续6个月。参与者的目标是在第8周增加到40分钟,之后增加跑步机的速度或等级。IC患者被鼓励进行接近最大腿部症状的运动。无症状的参与者在博格量表上的感知运动为12到14。抵抗组每周进行3次有监督的运动,持续6个月,包括3组8次重复的下肢抵抗运动。外部阻力维持在1次重复最大值的50%以上,并在12至14时感觉到劳累。对照组参加了11次会议,旨在提供与健康专业人员的联系,但不改变行为。主要结果是6个月时6分钟步行测试(6MWT)和短物理性能电池(SPPB)的变化。SPPB评估行走速度、平衡和坐立表现。次要结果测量是跑步机耐力、下肢力量、无创肱动脉内皮功能测量、7天内通过加速度计测量的习惯性身体活动、行走障碍问卷(WIQ)和SF-36生活质量问卷。结果与对照组相比,跑步机训练显著改善了6MW距离(36 m, 95% CI 15 ~ 57)、总跑步时间(3.4 min, 95% CI 2 ~ 4.8)、无痛跑步时间(1.6 min, 95% CI 0.3 ~ 2.9)、内皮功能和WIQ的距离域。与对照组相比,阻力训练显著改善了跑步机总时间(1.9分钟,95% CI 0.5至3.3),膝关节伸展强度(80 N, 95% CI 37至124),以及WIQ的距离和爬楼梯范围。两种方案在SF-36的生理功能领域都产生了显著的7.5分的改善。结论跑步机和阻力训练对外周动脉疾病患者的疗效不同,但均能提高患者的生活质量。
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引用次数: 1
Functional Independence Measure 功能独立性量表
Pub Date : 2009-01-01 DOI: 10.1016/S0004-9514(09)70066-2
Shylie Mackintosh
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引用次数: 160
期刊
Australian Journal of Physiotherapy
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