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Duration of antibiotic therapy and erythrocyte sedimentation rate predict blood culture results in children with acute osteomyelitis. 抗生素治疗时间和红细胞沉降率预测急性骨髓炎儿童血培养结果。
IF 1 4区 医学 Q4 ORTHOPEDICS Pub Date : 2025-11-03 DOI: 10.1097/BPB.0000000000001302
YuTing Wang, JiaZhi Yu, Tao Liu, HaiTing Jia

Blood cultures are routinely performed for microbiological diagnostic purposes in acute hematogenous osteomyelitis (AHO); however, the blood culture positivity rate is less than 50%. This retrospective study aimed to identify indicators to distinguish blood culture outcomes in children with AHO from July 2017 to 2024. Patients were stratified based on the results of blood cultures. The age, sex, duration of symptoms, duration of antibiotic therapy before blood culture, location of the lesion, maximum temperature, and inflammatory indexes from admission were reviewed. The efficacy of each index in diagnosing negative blood cultures was also determined according to the receiver operator curves. Logistic regression analysis was used to determine the independent risk factors for blood culture negativity. Among 75 patients, 47 had negative and 28 had positive cultures. No significant differences were found in age, sex, symptom duration, or leukocyte count. However, maximum temperature, duration of antibiotic therapy before culture, neutrophil count, C-reactive protein, and erythrocyte sedimentation rate (ESR) showed significant differences. Logistic regression identified antibiotic therapy duration >2.5 days (OR = 6.383, 95% CI: 1.720-23.680) and ESR <41.5 mm/h (OR = 12.377, 95% CI: 2.042-75.015) as independent risk factors for negative cultures. AHO patients with either of these factors are more likely to have negative blood cultures. For such children, early invasive procedures to obtain pus or tissue for culture should be considered.

在急性血液性骨髓炎中,常规进行血培养以进行微生物诊断(世卫组织);但血培养阳性率不足50%。本回顾性研究旨在确定指标,以区分2017年7月至2024年世卫组织患儿的血培养结果。根据血培养结果对患者进行分层。回顾患者的年龄、性别、症状持续时间、血培养前抗生素治疗时间、病变部位、最高体温和入院时的炎症指标。根据受试者操作曲线确定各指标对阴性血培养的诊断效果。采用Logistic回归分析确定血培养阴性的独立危险因素。75例患者中,47例培养阴性,28例培养阳性。年龄、性别、症状持续时间或白细胞计数均无显著差异。然而,培养前的最高温度、抗生素治疗时间、中性粒细胞计数、c反应蛋白和红细胞沉降率(ESR)存在显著差异。Logistic回归确定抗生素治疗持续时间>2.5天(OR = 6.383, 95% CI: 1.720-23.680)和ESR
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引用次数: 0
Scapular osteomyelitis, a challenging diagnosis: a systematic review in pediatric age. 肩胛骨骨髓炎,一个具有挑战性的诊断:儿科年龄的系统回顾。
IF 1 4区 医学 Q4 ORTHOPEDICS Pub Date : 2025-11-01 Epub Date: 2025-06-30 DOI: 10.1097/BPB.0000000000001271
Ilaria Liguoro, Sarah Ortis, Francesco Mancuso, Michele Patui, Paola Cogo, Chiara Pilotto

Osteomyelitis of the scapula is a rare site of bone infection. Early diagnosis is difficult because of the rarity of localization, the rapid progression, and the misleading atypical manifestations. We systematically reviewed the current available evidence on osteomyelitis of the scapula to provide a synthesis on the epidemiology, clinical presentation, complications, and management of this infection. PubMed, Scopus, and Google Scholar databases were explored to identify studies, case series, and case reports with no time limits focused on children with scapular osteomyelitis. Thirteen articles were included in the final analysis, for a total of 17 patients (14 children and three newborns). The most frequently reported symptoms in children were pain (100%), limitation of shoulder movements (100%), and fever (79%). Several imaging tests were adopted (X-ray, ultrasound, computed tomography scan, and MRI) with pathological findings in most cases. Blood tests always showed a phlogistic state. The most frequent causative agent was methicillin-sensitive Staphylococcus aureus in children and group B Streptococcus in newborns. The mean total duration of antibiotic treatment was 51.5 days, with intravenous cephalosporins (43%), penicillins (36%), and aminoglycosides (29%) adopted as first-choice antibiotics in most cases. Full recovery was reported in most cases (79% in children). Osteomyelitis should be suspected in cases of osteomuscular symptoms even in the absence of fever or local signs. Inflammatory indices and white blood cell count can be only slightly elevated and normal X-rays cannot exclude the diagnosis, and in case of suspicion, MRI is mandatory.

肩胛骨骨髓炎是一种罕见的骨感染部位。早期诊断是困难的,因为罕见的定位,迅速的进展,和误导的非典型表现。我们系统地回顾了目前关于肩胛骨骨髓炎的现有证据,以提供这种感染的流行病学,临床表现,并发症和治疗的综合。我们对PubMed、Scopus和谷歌Scholar数据库进行了研究,以确定无时间限制的关于儿童肩胛骨骨髓炎的研究、病例系列和病例报告。最终分析纳入13篇文章,共17例患者(14例儿童和3例新生儿)。儿童最常见的报告症状是疼痛(100%)、肩部活动受限(100%)和发烧(79%)。采用多种影像学检查(x线、超声、计算机断层扫描和MRI),多数病例有病理表现。血液检查总是显示有炎症最常见的病原体是儿童的甲氧西林敏感金黄色葡萄球菌和新生儿的B群链球菌。抗生素治疗的平均总持续时间为51.5天,以静脉注射头孢菌素(43%)、青霉素类(36%)和氨基糖苷类(29%)为首选抗生素的病例居多。大多数病例报告完全康复(儿童79%)。即使在没有发烧或局部体征的情况下,也应怀疑骨髓炎。炎症指数和白细胞计数只能轻微升高,正常x光片不能排除诊断,如有怀疑,必须进行MRI检查。
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引用次数: 0
A note of thanks to referees. 感谢裁判。
IF 1 4区 医学 Q4 ORTHOPEDICS Pub Date : 2025-11-01 Epub Date: 2025-09-30 DOI: 10.1097/BPB.0000000000001296
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引用次数: 0
Comparing the outcomes between conventional osteotomy and with the adjunct use of 3-dimensional printing in paediatric deformity osteotomy correction: a systematic review and meta-analysis. 比较常规截骨术和辅助使用三维打印在小儿畸形截骨矫正中的效果:系统回顾和荟萃分析。
IF 1 4区 医学 Q4 ORTHOPEDICS Pub Date : 2025-11-01 Epub Date: 2025-09-30 DOI: 10.1097/BPB.0000000000001242
Chen Xi Kasia Chua, Francis Jia Yi Fong, Jason Derry Onggo, Michael Gui Jie Yam

Recent advancements in medical technology have introduced three-dimensional (3D) printing as a promising adjunct to conventional osteotomy. This review aims to evaluate the clinical, radiological outcomes and complications of patients who underwent conventional osteotomy compared to osteotomy with the adjunct use of 3D printing in paediatric deformity correction. The review was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The current study searched from inception to April 2023. All studies that compared outcomes between conventional osteotomy and osteotomy with the adjunct use of 3D printing in paediatric deformity correction in both upper and lower limbs were included. A total of 13 publications with 482 patients were included in this review. In terms of intraoperative parameters, the 3D group had a shorter operative time by 21.3 min [95% confidence interval (CI): 15.92-26.85] and less radiation exposure of -3.42 times (95% CI: -4.57 to -2.28). For radiological outcomes, 3D group had a smaller mean osteotomy error of -2.03 degrees (95% CI: -3.84 to -0.22) and 1.94 times higher odds (95% CI: 1.08-3.48) of having better radiological outcomes. The conventional osteotomy group has possibly a 1.4 risk (95% CI: 0.32-1.59) of growth plate, articular or risk of avascular necrosis compared to 3D templated group. The findings of this meta-analysis support the use of 3D printing as an adjunct in paediatric deformity correction for better intraoperative outcomes, reduce radiation exposure and better radiological accuracy in both upper and lower limb surgery.

最近医疗技术的进步已经引入了三维(3D)打印作为传统截骨术的一个有前途的辅助手段。本综述旨在评估常规截骨术与辅助使用3D打印截骨术在小儿畸形矫正中的临床、影像学结果和并发症。该评价按照系统评价和荟萃分析指南的首选报告项目进行。目前的研究从开始到2023年4月。所有比较常规截骨术与辅助使用3D打印截骨术在小儿上肢和下肢畸形矫正中的效果的研究均被纳入。本综述共纳入13篇出版物,涉及482例患者。术中参数方面,3D组手术时间缩短21.3 min[95%可信区间(CI): 15.92 ~ 26.85],辐射暴露减少-3.42次(95% CI: -4.57 ~ -2.28)。放射学结果方面,3D组平均截骨误差较小,为-2.03度(95% CI: -3.84 ~ -0.22),较好的放射学结果的几率高1.94倍(95% CI: 1.08 ~ 3.48)。与3D模板组相比,常规截骨组生长板、关节或无血管性坏死的风险可能为1.4 (95% CI: 0.32-1.59)。这项荟萃分析的结果支持将3D打印作为儿科畸形矫正的辅助手段,在上肢和下肢手术中获得更好的术中结果,减少辐射暴露和更好的放射准确性。
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引用次数: 0
Intramedullary nailing of pediatric femoral fractures with postless technique: technique and early results. 无后位髓内钉治疗小儿股骨骨折:技术及早期结果。
IF 1 4区 医学 Q4 ORTHOPEDICS Pub Date : 2025-11-01 Epub Date: 2025-07-31 DOI: 10.1097/BPB.0000000000001279
Sahand Fallahi, Purav S Brahmbhatt, Sivashanmugam Raju

This study aims to describe the novel technique of intramedullary nailing of pediatric femoral fractures with a postless distraction technique and to report the technique's safety, complications, and early clinical outcomes. A retrospective review was performed of pediatric patients at a single urban level I trauma center who underwent femoral nailing using the postless distraction technique. The senior author performed all procedures. We collected the following data for patients meeting inclusion criteria: age, sex, height, weight, BMI, fracture classification, quality of fracture reduction, intraoperative time, length of follow-up, and postoperative complications. There were 17 patients in our study. On average, patients were 14 years old (range 11-17 years) with a BMI of 24.73 kg/m 2 (19.37-32.66 kg/m 2 ). The mean length of follow-up for all patients was 41 weeks (6-100 weeks). There were no immediate or early postoperative complications during the follow-up of all patients. The use of a postless system allows for accurate, reproducible, and safe management of femoral fractures in the pediatric population. This project demonstrates the safety and feasibility of this technique, even in a child of small stature. Furthermore, pediatric femoral nailing using a postless system has not been previously described in the literature. This is the first study to describe this surgical technique.

本研究旨在描述采用无后撑开技术髓内钉治疗小儿股骨骨折的新技术,并报告该技术的安全性、并发症和早期临床结果。回顾性回顾了在单一城市一级创伤中心使用无后牵引技术进行股骨钉固定的儿科患者。资深作者完成了所有程序。我们收集了符合纳入标准的患者的以下数据:年龄、性别、身高、体重、BMI、骨折分型、骨折复位质量、术中时间、随访时间、术后并发症。我们的研究中有17例患者。患者平均年龄14岁(11 ~ 17岁),BMI为24.73 kg/m2 (19.37 ~ 32.66 kg/m2)。所有患者的平均随访时间为41周(6-100周)。所有患者随访期间均未出现术后早期或即刻并发症。使用无支架系统可以对儿童股骨骨折进行准确、可重复性和安全的治疗。这个项目证明了这种技术的安全性和可行性,即使是在一个身材矮小的孩子身上。此外,使用无桩系统的儿科股内钉在以前的文献中没有描述过。这是第一个描述这种手术技术的研究。
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引用次数: 0
Social media as an information source for pediatric musculoskeletal infections: a quality analysis of English language content. 社交媒体作为儿童肌肉骨骼感染的信息源:英语内容的质量分析。
IF 1 4区 医学 Q4 ORTHOPEDICS Pub Date : 2025-11-01 Epub Date: 2025-07-17 DOI: 10.1097/BPB.0000000000001273
Michael William Stickels, Varun Mahadevan, Kajol Majhail, Meghana Belthur, M'Hamed Temkit, Amirreza Fatehi, Mohan V Belthur

Social media is an accessible information source for patients and families but data on its educational veracity for pediatric musculoskeletal infections are limited. We aim to explore this gap by quantifying information quality on three social media platforms for two infections: acute hematogenous osteomyelitis and septic arthritis. Facebook, YouTube, and Instagram were searched using the keywords 'acute hematogenous osteomyelitis' and 'septic arthritis'. Four raters with medical backgrounds evaluated posts using the modified DISCERN 16-point scoring system to quantify educational value. The intraclass correlation coefficient measured the reviewers' agreement, group differences were analyzed using Kruskal-Wallis and Wilcox-rank sum tests, and predictors for DISCERN scoring were calculated with linear regression. Pairwise comparisons among septic arthritis posts showed higher scores with YouTube ( n  = 50, 45.41 ± 12.44) than for Facebook ( n  = 34, 32.70 ± 8.73) and Instagram ( n  = 100, 24.71 ± 4.68) ( P  < 0.001). For osteomyelitis, pairwise comparisons showed higher scores for YouTube ( n  = 50, 46.62 ± 6.29) versus Facebook ( n  = 19, 37.95 ± 9.69) and Instagram posts ( n  = 100, 36.14 ± 6.16) ( P  < 0.001). When aggregating infections, YouTube had the highest DISCERN score (46.01 ± 9.83) followed by Facebook (34.58 ± 9.35) and Instagram (30.42 ± 7.91); all pairwise comparisons were significantly different (all P  < 0.001). Across all posts, authorship from medical institutions was associated with higher DISCERN scoring ( P  < 0.001). Social media lacks educational veracity for pediatric musculoskeletal infections. Patients using social media as an information source for these diseases should preferentially gather information from medical institutions.

对于患者和家庭来说,社交媒体是一个可访问的信息来源,但关于儿童肌肉骨骼感染教育准确性的数据有限。我们的目标是通过量化三个社交媒体平台上两种感染的信息质量来探索这一差距:急性血液性骨髓炎和脓毒性关节炎。Facebook、YouTube和Instagram的搜索关键词是“急性血液性骨髓炎”和“化脓性关节炎”。四名具有医学背景的评分者使用改进的DISCERN 16分评分系统对职位进行评估,以量化教育价值。类内相关系数衡量评论者的一致性,组间差异分析采用Kruskal-Wallis和wilcox秩和检验,并采用线性回归计算DISCERN评分的预测因子。脓毒性关节炎帖子的两两比较显示,YouTube评分(n = 50, 45.41±12.44)高于Facebook (n = 34, 32.70±8.73)和Instagram (n = 100, 24.71±4.68)
{"title":"Social media as an information source for pediatric musculoskeletal infections: a quality analysis of English language content.","authors":"Michael William Stickels, Varun Mahadevan, Kajol Majhail, Meghana Belthur, M'Hamed Temkit, Amirreza Fatehi, Mohan V Belthur","doi":"10.1097/BPB.0000000000001273","DOIUrl":"10.1097/BPB.0000000000001273","url":null,"abstract":"<p><p>Social media is an accessible information source for patients and families but data on its educational veracity for pediatric musculoskeletal infections are limited. We aim to explore this gap by quantifying information quality on three social media platforms for two infections: acute hematogenous osteomyelitis and septic arthritis. Facebook, YouTube, and Instagram were searched using the keywords 'acute hematogenous osteomyelitis' and 'septic arthritis'. Four raters with medical backgrounds evaluated posts using the modified DISCERN 16-point scoring system to quantify educational value. The intraclass correlation coefficient measured the reviewers' agreement, group differences were analyzed using Kruskal-Wallis and Wilcox-rank sum tests, and predictors for DISCERN scoring were calculated with linear regression. Pairwise comparisons among septic arthritis posts showed higher scores with YouTube ( n  = 50, 45.41 ± 12.44) than for Facebook ( n  = 34, 32.70 ± 8.73) and Instagram ( n  = 100, 24.71 ± 4.68) ( P  < 0.001). For osteomyelitis, pairwise comparisons showed higher scores for YouTube ( n  = 50, 46.62 ± 6.29) versus Facebook ( n  = 19, 37.95 ± 9.69) and Instagram posts ( n  = 100, 36.14 ± 6.16) ( P  < 0.001). When aggregating infections, YouTube had the highest DISCERN score (46.01 ± 9.83) followed by Facebook (34.58 ± 9.35) and Instagram (30.42 ± 7.91); all pairwise comparisons were significantly different (all P  < 0.001). Across all posts, authorship from medical institutions was associated with higher DISCERN scoring ( P  < 0.001). Social media lacks educational veracity for pediatric musculoskeletal infections. Patients using social media as an information source for these diseases should preferentially gather information from medical institutions.</p>","PeriodicalId":50092,"journal":{"name":"Journal of Pediatric Orthopaedics-Part B","volume":" ","pages":"552-559"},"PeriodicalIF":1.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144762123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comments on 'Does tranexamic acid reduce blood loss for children undergoing reconstruction for neuromuscular hip dysplasia? A matched comparative study'. 关于“氨甲环酸能减少因神经肌肉髋关节发育不良而接受重建的儿童的失血量吗?”一项匹配的比较研究。
IF 1 4区 医学 Q4 ORTHOPEDICS Pub Date : 2025-11-01 Epub Date: 2025-09-30 DOI: 10.1097/BPB.0000000000001282
Rohit Kumar, Pritam Kumar Bhagat, Rahul Kumar, Aman Kumar, Baibhav Mishra, Shubhav Sharma, Vikash Raj
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引用次数: 0
Age filtering in a TriNetX-based study of pediatric rickets. 基于trinetx的儿童佝偻病研究中的年龄过滤。
IF 1 4区 医学 Q4 ORTHOPEDICS Pub Date : 2025-11-01 Epub Date: 2025-09-30 DOI: 10.1097/BPB.0000000000001290
Miley Wang, Tsai-Chieh Hou, Joshua Wang
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引用次数: 0
A pilot study of gait compensation for limb-length discrepancy in children and adolescents: threshold values and compensatory strategies in the sagittal plane. 儿童和青少年肢体长度差异步态补偿的初步研究:矢状面阈值和补偿策略。
IF 1 4区 医学 Q4 ORTHOPEDICS Pub Date : 2025-11-01 Epub Date: 2025-05-20 DOI: 10.1097/BPB.0000000000001265
An Seong Chang, Hae-Ryong Song, Mi Hyun Song

The critical threshold of limb-length discrepancy (LLD) at which compensation strategies are initiated in pediatric patients is unclear. We used spatiotemporal parameters to determine the LLD threshold at which compensatory gait is induced in skeletally immature patients and analyzed these compensatory patterns in terms of kinematics and kinetics. The findings for 20 children who experienced LLD-associated gait discomfort and underwent three-dimensional gait analysis between 2016 and 2019 were reviewed. Using spatiotemporal parameters, the LLD threshold that causes gait asymmetry was determined by receiver operating characteristic (ROC) analysis. Patients were grouped into those with an LLD greater than the cutoff value and those without. The kinematics and kinetics of the two groups were compared. The ROC curve showed that step length was a critical indicator of gait compensation. The area under the curve was 0.882 for both absolute LLD and LLD ratio, with threshold values of 14.06 mm and 1.85%, respectively. The group with LLDs above the threshold showed significant interlimb differences in the hip flexion angle, ankle dorsiflexion angle, and hip joint moment in the sagittal plane ( P  = 0.005, P  = 0.015, and P  = 0.047, respectively). Compensatory strategies for LLD began when the absolute LLD was 14.06 mm or the LLD ratio was 1.85%. These strategies included hip joint flexion, increased hip joint moment of the longer limb, and ankle joint plantar flexion of the shorter limb. Thus, even with LLD less than 2 cm, asymmetries may exist in joint kinematics and kinetics.

在补偿策略启动的儿科患者肢体长度差异(LLD)的临界阈值尚不清楚。我们使用时空参数来确定骨骼不成熟患者诱导代偿步态的LLD阈值,并从运动学和动力学角度分析了这些代偿模式。对2016年至2019年期间20名患有lld相关步态不适并接受三维步态分析的儿童的研究结果进行了回顾。利用时空参数,通过受试者工作特征(receiver operating characteristic, ROC)分析确定引起步态不对称的LLD阈值。将患者分为LLD大于临界值组和LLD小于临界值组。比较两组的运动学和动力学。ROC曲线显示步长是步态补偿的重要指标。绝对LLD和LLD比值曲线下面积均为0.882,阈值分别为14.06 mm和1.85%。LLDs高于阈值组髋屈曲角、踝关节背屈角、矢状面髋关节力矩在肢间差异显著(P = 0.005、P = 0.015、P = 0.047)。当绝对LLD为14.06 mm或LLD比率为1.85%时,LLD的补偿策略开始。这些策略包括髋关节屈曲,增加长肢髋关节力矩,以及短肢踝关节足底屈曲。因此,即使LLD小于2 cm,关节运动学和动力学也可能存在不对称。
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引用次数: 0
A propensity score-adjusted retrospective analysis of after-hours and daytime surgery for Gartland type III pediatric supracondylar humeral fracture. Gartland III型儿童肱骨髁上骨折经倾向评分调整后的夜间和日间手术回顾性分析。
IF 1 4区 医学 Q4 ORTHOPEDICS Pub Date : 2025-11-01 Epub Date: 2025-08-29 DOI: 10.1097/BPB.0000000000001288
Ryota Sugimura, Hideaki Miyamoto, Takahiro Inui, Kensuke Ikuta, Gen Sasaki, Kentaro Matsui, Taketo Kurozumi, Yoshinobu Watanabe, Hirotaka Kawano

The optimal surgical timing for pediatric supracondylar humeral fractures has been deliberated. Although the recent trend is to postpone surgery until the daytime, the effect of after-hours surgery on outcomes requires further elucidation. Thus, we aimed to evaluate whether the timing of surgery for pediatric supracondylar humeral fractures affects the outcomes. The data of 135 pediatric patients who underwent surgery for Gartland type III supracondylar humeral fractures at a single trauma center were retrospectively analyzed. Depending on the time of admission to the operating room, the patients were divided into daytime and after-hours surgery cohorts. Nearest-neighbor propensity score matching was conducted, and outcomes were compared between the matched cohorts. The primary outcome was defined as reduction failure, including revision surgery. Secondary outcomes included the operative time, indication for open reduction, and complications. Each matched cohort consisted of 48 patients, with a mean age of 6.6 ± 2.6 years. The after-hours surgery resulted in more frequent reduction failures than the daytime surgery (21% vs. 4%, P  < 0.05). No significant differences were observed in the secondary outcomes. In the post hoc analysis, where the matched cohorts were stratified by the presence of supervising orthopedic trauma surgeons, reduction failure rates showed no statistically significant difference between daytime and after-hours surgery. This propensity score-adjusted retrospective study revealed that reduction failures occurred more frequently in after-hours surgeries than in daytime surgeries for pediatric supracondylar humeral fractures. The absence of supervising surgeons may have contributed to the poorer outcome of after-hours surgeries.

小儿肱骨髁上骨折的最佳手术时机一直在考虑中。虽然最近的趋势是将手术推迟到白天,但下班后手术对结果的影响需要进一步阐明。因此,我们的目的是评估小儿肱骨髁上骨折的手术时机是否会影响预后。回顾性分析135例在同一创伤中心接受Gartland III型肱骨髁上骨折手术的儿童患者的资料。根据患者进入手术室的时间,将患者分为白天和下班手术组。进行最近邻倾向评分匹配,并比较匹配队列之间的结果。主要结局定义为复位失败,包括翻修手术。次要结果包括手术时间、切开复位指征和并发症。每个匹配队列包括48例患者,平均年龄为6.6±2.6岁。夜间手术复位失败率高于日间手术(21% vs. 4%, P
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引用次数: 0
期刊
Journal of Pediatric Orthopaedics-Part B
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