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The hidden value of MRI: modifying treatment decisions in C-spine injuries 磁共振成像的隐藏价值:改变脊柱损伤的治疗决策
Pub Date : 2024-07-22 DOI: 10.1186/s13049-024-01235-9
Niklas Rutsch, Florian Schmaranzer, Pascale Amrein, Martin Müller, Christoph E. Albers, Sebastian F. Bigdon
Computed Tomography (CT) is the gold standard for cervical spine (c-spine) evaluation. Magnetic resonance imaging (MRI) emerges due to its increasing availability and the lack of radiation exposure. However, MRI is costly and time-consuming, questioning its role in the emergency department (ED). This study investigates the added the value of an additional MRI for patients presenting with a c-spine injury in the ED. We conducted a retrospective monocenter cohort study that included all patients with neck trauma presenting in the ED, who received imaging based on the NEXUS criteria. Spine surgeons performed a full-case review to classify each case into “c-spine injured” and “c-spine uninjured”. Injuries were classified according to the AO Spine classification. We assessed patients with a c-spine injury detected by CT, who received a subsequent MRI. In this subset, injuries were classified separately in both imaging modalities. We monitored the treatment changes after the additional MRI to evaluate characteristics of this cohort and the impact of the AO Spine Neurology/Modifier modifiers. We identified 4496 subjects, 2321 were eligible for inclusion and 186 were diagnosed with c-spine injuries in the retrospective case review. Fifty-six patients with a c-spine injury initially identified through CT received an additional MRI. The additional MRI significantly extended (geometric mean ratio 1.32, p < 0.001) the duration of the patients’ stay in the ED. Of this cohort, 25% had a change in treatment strategy and among the patients with neurological symptoms (AON ≥ 1), 45.8% experienced a change in treatment. Patients that were N-positive, had a 12.4 (95% CI 2.7–90.7, p < 0.01) times higher odds of a treatment change after an additional MRI than neurologically intact patients. Our study suggests that patients with a c-spine injury and neurological symptoms benefit from an additional MRI. In neurologically intact patients, an additional MRI retains value only when carefully evaluated on a case-by-case basis.
计算机断层扫描(CT)是评估颈椎的黄金标准。磁共振成像(MRI)因其日益普及且无辐射而兴起。然而,核磁共振成像既昂贵又耗时,这就对其在急诊科(ED)中的作用提出了质疑。本研究探讨了在急诊科对脊柱损伤患者进行额外核磁共振成像检查的附加价值。我们进行了一项回顾性单中心队列研究,纳入了所有在急诊科就诊的颈部创伤患者,他们都根据 NEXUS 标准接受了成像检查。脊柱外科医生对病例进行了全面审查,将每个病例分为 "颈椎受伤 "和 "颈椎未受伤 "两类。损伤根据 AO 脊柱分类法进行分类。我们评估了通过 CT 检测到 c 型脊柱损伤并随后接受了 MRI 检查的患者。在这一子集中,两种成像模式分别对损伤进行分类。我们对额外核磁共振成像后的治疗变化进行了监测,以评估该群体的特征以及 AO 脊柱神经学/调节器修饰符的影响。我们确定了 4496 名受试者,其中 2321 人符合纳入条件,186 人在回顾性病例审查中被诊断为 c 型脊柱损伤。最初通过 CT 确定为 c 型脊柱损伤的 56 名患者接受了额外的 MRI 检查。额外的核磁共振成像大大延长了患者在急诊室的住院时间(几何平均比为 1.32,P < 0.001)。其中,25%的患者改变了治疗策略,在有神经症状(AON ≥ 1)的患者中,45.8%的患者改变了治疗策略。与神经功能完好的患者相比,N阳性患者在接受一次额外的磁共振成像检查后改变治疗方案的几率要高出12.4倍(95% CI 2.7-90.7,p < 0.01)。我们的研究表明,有脊柱损伤和神经症状的患者可从额外的核磁共振成像中获益。对于神经系统完好的患者,只有根据具体情况进行仔细评估后,额外磁共振成像才有价值。
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引用次数: 0
Pediatric trauma patients in Swedish ambulance services -a retrospective observational study of assessments, interventions, and clinical outcomes 瑞典救护车服务中的小儿创伤患者 - 评估、干预和临床结果的回顾性观察研究
Pub Date : 2024-06-05 DOI: 10.1186/s13049-024-01222-0
Glenn Larsson, Sanna Larsson, Viktoria Strand, Carl Magnusson, Magnus Andersson Hagiwara
Pediatric trauma patients constitute a significant portion of the trauma population treated by Swedish Emergency Medical Services (EMS), and trauma remains a notable cause of death among Swedish children. Previous research has identified potential challenges in prehospital assessments and interventions for pediatric patients. In Sweden, there is limited information available regarding pediatric trauma patients in the EMS. The aim of this study was to investigate the prevalence of pediatric trauma patients within the Swedish EMS and describe the prehospital assessments, interventions, and clinical outcomes. This retrospective observational study was conducted in a region of Southwestern Sweden. A random sample from ambulance and hospital records from the year 2019 was selected. Inclusion criteria were children aged 0–16 years who were involved in trauma and assessed by EMS clinicians. A total of 440 children were included in the study, representing 8.4% of the overall trauma cases. The median age was 9 years (IQR 3–12), and 60.5% were male. The leading causes of injury were low (34.8%) and high energy falls (21%), followed by traffic accidents. The children were assessed as severely injured in 4.5% of cases. A quarter of the children remained at the scene after assessment. Complete vital signs were assessed in 29.3% of children, and 81.8% of children were assessed according to the ABCDE structure. The most common intervention performed by prehospital professionals was the administration of medication. The mortality rate was 0.2%. Pediatric trauma cases accounted for 8.4% of the overall trauma population with a variations in injury mechanisms and types. Vital sign assessments were incomplete for a significant proportion of children. The adherence to the ABCDE structure, however, was higher. The children remained at the scene after assessment requires further investigation for patient safety.
在瑞典急救医疗服务机构(EMS)收治的外伤患者中,儿童外伤患者占了很大一部分,而且外伤仍然是瑞典儿童死亡的一个重要原因。先前的研究已经发现了院前评估和干预儿科患者可能面临的挑战。在瑞典,有关急救医疗服务中儿科创伤患者的信息非常有限。本研究旨在调查瑞典急救服务中儿科创伤患者的发病率,并描述院前评估、干预措施和临床结果。这项回顾性观察研究在瑞典西南部的一个地区进行。研究人员从2019年的救护车和医院记录中随机抽样。纳入标准为0-16岁的儿童,这些儿童涉及创伤并接受过急救中心临床医生的评估。共有 440 名儿童被纳入研究,占创伤病例总数的 8.4%。中位年龄为 9 岁(IQR 3-12),60.5% 为男性。受伤的主要原因是低能量(34.8%)和高能量跌落(21%),其次是交通事故。4.5%的儿童被评估为严重受伤。四分之一的儿童在评估后仍留在现场。29.3%的儿童接受了完整的生命体征评估,81.8%的儿童按照ABCDE结构进行了评估。院前专业人员最常采取的干预措施是给药。死亡率为 0.2%。小儿外伤病例占外伤总人数的 8.4%,受伤机制和类型各不相同。相当一部分儿童的生命体征评估不完整。不过,对 ABCDE 结构的遵守程度较高。为了患者的安全,需要对评估后仍留在现场的儿童进行进一步调查。
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引用次数: 0
Procedural sedation by advanced practice providers in the emergency medical service in the Netherlands: a retrospective study 荷兰急救医疗服务中高级医疗人员的手术镇静:一项回顾性研究
Pub Date : 2024-05-01 DOI: 10.1186/s13049-024-01207-z
Risco van Vliet, Lennert Breedveld, Annemieke A.J. Heutinck, Bram H.A. Ockeloen, Arnoud W.J. van ’ Hof, Xavier R.J. Moors
Procedural sedation and analgesia (PSA) is a technique of administering sedatives to induce a state that allows the patient to tolerate painful procedures while maintaining cardiorespiratory function, a condition that is frequently desired prehospital. Non-physician prehospital clinicians often have a limited scope of practice when it comes to providing analgesia and sedation; sometimes resulting in a crew request for back-up from physician-staffed prehospital services.“. This is also the case if sedation is desirable. Advanced practice providers (APPs), who are legally authorized and trained to carry out this procedure, may be a solution when the physician-staffed service is not available or will not be available in time. The aim of this study is to gain insight in the circumstances in which an APP, working at the Dutch ambulance service “RAV Brabant MWN” from January 2019 to December 2022, uses propofol for PSA or to provide sedation. With this a retrospective observational document study we describe the characteristics of patients and ambulance runs and evaluates the interventions in terms of safety. During the study period, the APPs administered propofol 157 times for 135 PSA and in 22 cases for providing sedation. The most common indication was musculoskeletal trauma such as fracture care or the reduction of joint dislocation. In 91% of the situations where propofol was used, the predetermined goal e.g. alignment of fractured extremity, repositioning of luxated joint or providing sedation the goal was achieved. There were 12 cases in which one or more adverse events were documented and all were successfully resolved by the APP. There were no cases of laryngospam, airway obstruction, nor anaphylaxis. None of the adverse events led to unexpected hospitalization or death. During the study period, the APPs performed 135 PSAs and provided 22 sedations. The success rate of predetermined goals was higher than that stated in the literature. Although there were a number of side effects, their incidences were lower than those reported in the literature, and these were resolved by the APP during the episode of care. Applying a PSA by an APP at the EMS “RAV Brabant MWN” appears to be safe with a high success rate.
程序性镇静和镇痛(PSA)是一种使用镇静剂的技术,目的是让病人在保持心肺功能的同时,能够忍受疼痛的程序,这是院前经常需要的一种状态。在提供镇痛和镇静方面,非医生的院前临床医生的执业范围往往有限;有时会导致机组人员请求配备医生的院前服务机构提供支援"。如果需要镇静,情况也是如此。高级医疗服务提供者 (APP) 拥有合法授权并接受过相关培训,可在没有或无法及时提供由医生提供的服务时执行该程序。本研究旨在了解 2019 年 1 月至 2022 年 12 月在荷兰救护车服务机构 "RAV Brabant MWN "工作的 APP 使用异丙酚进行 PSA 或提供镇静的情况。通过这项回顾性观察记录研究,我们描述了患者和救护车运行的特点,并对干预措施的安全性进行了评估。在研究期间,APPs 共使用异丙酚 157 次,用于 135 例 PSA,22 例用于镇静。最常见的适应症是肌肉骨骼创伤,如骨折护理或关节脱位复位。在使用异丙酚的情况中,91%达到了预定目标,如骨折肢体对位、关节脱位复位或提供镇静。有 12 个病例记录了一个或多个不良事件,所有不良事件均由 APP 成功解决。没有发生喉痉挛、气道阻塞或过敏性休克。没有一起不良事件导致意外住院或死亡。在研究期间,APP 共执行了 135 次 PSA,提供了 22 次镇静。预定目标的成功率高于文献报道。虽然出现了一些副作用,但其发生率低于文献报道,而且这些副作用都在护理过程中由 APP 解决。在急救中心 "RAV Brabant MWN",APP 应用 PSA 似乎是安全的,成功率也很高。
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引用次数: 0
Development of a trigger tool to identify harmful incidents, no harm incidents, and near misses in prehospital emergency care 开发一种触发工具,用于识别院前急救中的有害事件、无害事件和险情
Pub Date : 2024-04-29 DOI: 10.1186/s13049-024-01209-x
Niclas Packendorff, Carl Magnusson, Kristoffer Wibring, Christer Axelsson, Magnus Andersson Hagiwara
Emergency Medical Services (EMS) are a unique setting because care for the chief complaint is given across all ages in a complex and high-risk environment that may pose a threat to patient safety. Traditionally, a reporting system is commonly used to raise awareness of adverse events (AEs); however, it could fail to detect an AE. Several methods are needed to evaluate patient safety in EMS. In this light, this study was conducted to (1) develop a national ambulance trigger tool (ATT) with a guide containing descriptions of triggers, examples of use, and categorization of near misses (NMs), no harm incidents (NHIs), and harmful incidents (HIs) and (2) use the ATT on randomly selected ambulance records. The ambulance trigger tool was developed in a stepwise manner through (1) a literature review; (2) three sessions of structured group discussions with an expert panel having knowledge of emergency medical service, patient safety, and development of trigger tools; (3) a retrospective record review of 900 randomly selected journals with three review teams from different geographical locations; and (4) inter-rater reliability testing between reviewers. From the literature review, 34 triggers were derived. After removing clinically irrelevant ones and combining others through three sessions of structured discussions, 19 remained. The most common triggers identified in the 900 randomly selected records were deviation from treatment guidelines (30.4%), the patient is non conveyed after EMS assessment (20.8%), and incomplete documentation (14.4%). The positive triggers were categorized as a near miss (40.9%), no harm (3.7%), and harmful incident (0.2%). Inter-rater reliability testing showed good agreement in both sessions. This study shows that a trigger tool together with a retrospective record review can be used as a method to measure the frequency of harmful incidents, no harm incidents, and near misses in the EMS, thus complementing the traditional reporting system to realize increased patient safety. What is already known on this topic: The EMS system is potentially a high-risk environment for harmful incidents, and a reporting system could fail to detect adverse events; thus, new methods are needed. What this study adds: This study adds an ATT to the clinical practice to complement the reporting system for the detection of harmful incidents, no harm incidents, and near misses and thus realize increased patient safety in EMS. How this study might affect research, practice, or policy: The detection of harmful incidents, no harm incidents, and near misses in EMS could serve as a foundation for improving patient safety.
紧急医疗服务(EMS)是一种独特的环境,因为在复杂和高风险的环境中,所有年龄段的患者都要接受主诉护理,这可能会对患者的安全构成威胁。传统上,报告系统通常用于提高对不良事件(AEs)的认识;但它可能无法检测到不良事件。评估急救医疗服务中的患者安全需要多种方法。有鉴于此,本研究(1)开发了一个全国性的救护车触发工具(ATT),并提供了一份指南,其中包含触发器的描述、使用示例以及险情(NMs)、无伤害事件(NHIs)和有害事件(HIs)的分类;(2)在随机抽取的救护车记录中使用该工具。救护车触发工具是通过以下步骤逐步开发的:(1)文献综述;(2)与具有急救医疗服务、患者安全和触发工具开发知识的专家小组进行三次结构化小组讨论;(3)由来自不同地区的三个评审小组对随机抽取的 900 份日志进行回顾性记录评审;以及(4)评审员之间的互评可靠性测试。从文献综述中得出了 34 项触发因素。通过三次结构化讨论,删除了与临床无关的触发因素,并合并了其他触发因素,最后剩下 19 个触发因素。在随机抽取的 900 份记录中,最常见的触发因素是偏离治疗指南(30.4%)、急救服务评估后未转送患者(20.8%)和记录不完整(14.4%)。正面触发因素分为险情(40.9%)、无伤害(3.7%)和有害事件(0.2%)。评分者之间的可靠性测试表明,两次评分的一致性都很好。这项研究表明,触发工具和回顾性记录审查可作为一种方法,用于测量急救服务中有害事件、无害事件和险情的发生频率,从而与传统的报告系统相辅相成,实现患者安全的提高。关于此主题的已知信息:急救系统可能是有害事件的高风险环境,而报告系统可能无法发现不良事件;因此,需要新的方法。本研究的补充:本研究为临床实践增添了一种 ATT 方法,以补充检测有害事件、无害事件和险情的报告系统,从而提高急救服务中的患者安全。本研究对研究、实践或政策有何影响?发现急救服务中的有害事件、无害事件和险情可作为提高患者安全的基础。
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引用次数: 0
The skåne emergency medicine (SEM) cohort 瑞典急诊医学(SEM)队列
Pub Date : 2024-04-26 DOI: 10.1186/s13049-024-01206-0
Ulf Ekelund, Bodil Ohlsson, Olle Melander, Jonas Björk, Mattias Ohlsson, Jakob Lundager Forberg, Pontus Olsson de Capretz, Axel Nyström, Anders Björkelund
In the European Union alone, more than 100 million people present to the emergency department (ED) each year, and this has increased steadily year-on-year by 2–3%. Better patient management decisions have the potential to reduce ED crowding, the number of diagnostic tests, the use of inpatient beds, and healthcare costs. We have established the Skåne Emergency Medicine (SEM) cohort for developing clinical decision support systems (CDSS) based on artificial intelligence or machine learning as well as traditional statistical methods. The SEM cohort consists of 325 539 unselected unique patients with 630 275 visits from January 1st, 2017 to December 31st, 2018 at eight EDs in the region Skåne in southern Sweden. Data on sociodemographics, previous diseases and current medication are available for each ED patient visit, as well as their chief complaint, test results, disposition and the outcome in the form of subsequent diagnoses, treatments, healthcare costs and mortality within a follow-up period of at least 30 days, and up to 3 years. The SEM cohort provides a platform for CDSS research, and we welcome collaboration. In addition, SEM’s large amount of real-world patient data with almost complete short-term follow-up will allow research in epidemiology, patient management, diagnostics, prognostics, ED crowding, resource allocation, and social medicine.
仅在欧盟,每年就有超过一亿人到急诊科(ED)就诊,并且每年以 2-3% 的速度稳步增长。更好的患者管理决策有可能减少急诊室的拥挤程度、诊断检测的数量、住院床位的使用以及医疗成本。我们建立了斯科纳急诊医学(SEM)队列,用于开发基于人工智能或机器学习以及传统统计方法的临床决策支持系统(CDSS)。SEM 队列由 325 539 名未经选择的患者组成,这些患者在 2017 年 1 月 1 日至 2018 年 12 月 31 日期间在瑞典南部斯科讷地区的八家急诊室就诊 630 275 次。每个急诊室就诊患者的社会人口学、既往疾病和当前用药数据,以及他们的主诉、检查结果、处置和随访期至少 30 天、最长 3 年的后续诊断、治疗、医疗费用和死亡率等结果。SEM 队列为 CDSS 研究提供了一个平台,我们欢迎合作。此外,SEM 的大量真实患者数据和几乎完整的短期随访将有助于流行病学、患者管理、诊断、预后、急诊室拥挤、资源分配和社会医学方面的研究。
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引用次数: 0
A retrospective analysis of mission reports in the national Swedish Police Registry on mountain rescue 2018-2022: here be snowmobiles. 对瑞典国家警察登记处 2018-2022 年山地救援任务报告的回顾分析:这里是雪地摩托。
Pub Date : 2024-04-25 DOI: 10.1186/s13049-024-01210-4
Anton Westman, Johanna Björnstig
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引用次数: 0
Effect of a vapor barrier in combination with active external rewarming for cold-stressed patients in a prehospital setting: a randomized, crossover field study 在院前环境中,水汽屏障与主动体外复温相结合对冷应激患者的影响:一项随机、交叉实地研究
Pub Date : 2024-04-25 DOI: 10.1186/s13049-024-01204-2
S. Mydske, Guttorm Brattebø, Øyvind Østerås, Øystein Wiggen, Jörg Assmus, Ø. Thomassen
{"title":"Effect of a vapor barrier in combination with active external rewarming for cold-stressed patients in a prehospital setting: a randomized, crossover field study","authors":"S. Mydske, Guttorm Brattebø, Øyvind Østerås, Øystein Wiggen, Jörg Assmus, Ø. Thomassen","doi":"10.1186/s13049-024-01204-2","DOIUrl":"https://doi.org/10.1186/s13049-024-01204-2","url":null,"abstract":"","PeriodicalId":501057,"journal":{"name":"Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140658440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of airway patency and air pocket in critically buried avalanche victims - a scoping review 雪崩重度掩埋者气道通畅和气囊的发生率--范围审查
Pub Date : 2024-04-23 DOI: 10.1186/s13049-024-01205-1
Frederik Eisendle, Simon Rauch, B. Wallner, H. Brugger, G. Strapazzon
{"title":"Prevalence of airway patency and air pocket in critically buried avalanche victims - a scoping review","authors":"Frederik Eisendle, Simon Rauch, B. Wallner, H. Brugger, G. Strapazzon","doi":"10.1186/s13049-024-01205-1","DOIUrl":"https://doi.org/10.1186/s13049-024-01205-1","url":null,"abstract":"","PeriodicalId":501057,"journal":{"name":"Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140671678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development and internal validation of an algorithm for estimating mortality in patients encountered by physician-staffed helicopter emergency medical services 开发并在内部验证一种算法,用于估算由配备医生的直升机紧急医疗服务遇到的病人的死亡率
Pub Date : 2024-04-23 DOI: 10.1186/s13049-024-01208-y
Emil Reitala, Mitja Lääperi, M. Skrifvars, Tom Silfvast, Hanna Vihonen, Pamela Toivonen, M. Tommila, L. Raatiniemi, Jouni Nurmi
{"title":"Development and internal validation of an algorithm for estimating mortality in patients encountered by physician-staffed helicopter emergency medical services","authors":"Emil Reitala, Mitja Lääperi, M. Skrifvars, Tom Silfvast, Hanna Vihonen, Pamela Toivonen, M. Tommila, L. Raatiniemi, Jouni Nurmi","doi":"10.1186/s13049-024-01208-y","DOIUrl":"https://doi.org/10.1186/s13049-024-01208-y","url":null,"abstract":"","PeriodicalId":501057,"journal":{"name":"Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140670793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute patients discharged without an established diagnosis: risk of mortality and readmission of nonspecific diagnoses compared to disease-specific diagnoses 未经确诊出院的急症患者:非特异性诊断与疾病特异性诊断的死亡率和再入院风险比较
Pub Date : 2024-04-19 DOI: 10.1186/s13049-024-01191-4
Rasmus Gregersen, Marie Villumsen, Katarina Høgh Mottlau, Cathrine Fox Maule, Hanne Nygaard, Jens Henning Rasmussen, Mikkel Bring Christensen, Janne Petersen
Nonspecific discharge diagnoses after acute hospital courses represent patients discharged without an established cause of their complaints. These patients should have a low risk of adverse outcomes as serious conditions should have been ruled out. We aimed to investigate the mortality and readmissions following nonspecific discharge diagnoses compared to disease-specific diagnoses and assessed different nonspecific subgroups. Register-based cohort study including hospital courses beginning in emergency departments across 3 regions of Denmark during March 2019–February 2020. We identified nonspecific diagnoses from the R- and Z03-chapter in the ICD-10 classification and excluded injuries, among others—remaining diagnoses were considered disease-specific. Outcomes were 30-day mortality and readmission, the groups were compared by Cox regression hazard ratios (HR), unadjusted and adjusted for socioeconomics, comorbidity, administrative information and laboratory results. We stratified into short (3–<12 h) or lengthier (12–168 h) hospital courses. We included 192,185 hospital courses where nonspecific discharge diagnoses accounted for 50.7% of short and 25.9% of lengthier discharges. The cumulative risk of mortality for nonspecific vs. disease-specific discharge diagnoses was 0.6% (0.6–0.7%) vs. 0.8% (0.7–0.9%) after short and 1.6% (1.5–1.7%) vs. 2.6% (2.5–2.7%) after lengthier courses with adjusted HRs of 0.97 (0.83–1.13) and 0.94 (0.85–1.05), respectively. The cumulative risk of readmission for nonspecific vs. disease-specific discharge diagnoses was 7.3% (7.1–7.5%) vs. 8.4% (8.2–8.6%) after short and 11.1% (10.8–11.5%) vs. 13.7% (13.4–13.9%) after lengthier courses with adjusted HRs of 0.94 (0.90–0.98) and 0.95 (0.91–0.99), respectively. We identified 50 clinical subgroups of nonspecific diagnoses, of which Abdominal pain (n = 12,462; 17.1%) and Chest pain (n = 9,599; 13.1%) were the most frequent. The subgroups described differences in characteristics with mean age 41.9 to 80.8 years and mean length of stay 7.1 to 59.5 h, and outcomes with < 0.2–8.1% risk of 30-day mortality and 3.5–22.6% risk of 30-day readmission. In unadjusted analyses, nonspecific diagnoses had a lower risk of mortality and readmission than disease-specific diagnoses but had a similar risk after adjustments. We identified 509 clinical subgroups of nonspecific diagnoses with vastly different characteristics and prognosis.
急性住院治疗后的非特异性出院诊断是指患者出院时没有明确的主诉原因。这些患者的不良后果风险应该很低,因为严重的疾病应该已经被排除。我们旨在调查非特异性出院诊断与疾病特异性诊断相比的死亡率和再入院率,并评估不同的非特异性亚组。基于登记的队列研究包括2019年3月至2020年2月期间丹麦3个地区急诊科开始的住院治疗。我们从 ICD-10 分类的 R 章和 Z03 章中确定了非特异性诊断,并排除了受伤等诊断--剩余的诊断被视为疾病特异性诊断。结果为 30 天死亡率和再入院率,通过 Cox 回归危险比(HR)对各组进行比较,未经调整或根据社会经济、合并症、管理信息和实验室结果进行调整。我们将住院时间分为短(3-<12 小时)和长(12-168 小时)两类。我们纳入了 192,185 个住院病程,其中非特异性出院诊断占短期出院病程的 50.7%,占长期出院病程的 25.9%。非特异性出院诊断与疾病特异性出院诊断的累积死亡率风险分别为:短病程为 0.6% (0.6-0.7%) vs. 0.8% (0.7-0.9%),长病程为 1.6% (1.5-1.7%) vs. 2.6% (2.5-2.7%),调整后 HR 分别为 0.97 (0.83-1.13) 和 0.94 (0.85-1.05)。非特异性出院诊断与疾病特异性出院诊断的累积再入院风险分别为:短期疗程为 7.3% (7.1-7.5%) vs. 8.4% (8.2-8.6%),长期疗程为 11.1% (10.8-11.5%) vs. 13.7% (13.4-13.9%),调整后的 HR 分别为 0.94 (0.90-0.98) 和 0.95 (0.91-0.99)。我们确定了 50 个非特异性诊断的临床亚组,其中腹痛(n = 12,462; 17.1%)和胸痛(n = 9,599; 13.1%)最为常见。亚组的特征存在差异,平均年龄为 41.9 岁至 80.8 岁,平均住院时间为 7.1 小时至 59.5 小时,30 天死亡风险< 0.2%至 2.8%,30 天再入院风险为 3.5%至 22.6%。在未调整分析中,非特异性诊断的死亡率和再入院风险低于疾病特异性诊断,但调整后风险相似。我们确定了 509 个非特异性诊断临床亚组,这些亚组的特征和预后大不相同。
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Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
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