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Never too young for a salivary gland carcinoma ex-pleomorphic adenoma 唾液腺癌前乳头状腺瘤永远不会太年轻
Pub Date : 2024-01-25 DOI: 10.1186/s43163-024-00575-8
Ahmad Muizzuddin Ahmad Fuad, Lum Sai Guan, Mohd Razif Mohamad Yunus
Carcinoma ex-pleomorphic adenoma (CXPA) can either arise primarily as a de novo or from the malignant transformation of a benign pleomorphic adenoma (PA). CXPA mostly occurs in adults aged 50 to 70 years; hence, the occurrence of CXPA in younger ages is not common. We report a 27-year-old female who had a history of submandibulectomy for pleomorphic adenoma, and presented with recurrent left submandibular swelling for 4 months. The mass was rapidly increasing in size and was associated with occasional throbbing pain. Examination showed a multilobulated, firm left submandibular swelling with no overlying skin changes. FNAC was performed twice, by conventional and ultrasound-guided techniques, and both concluded as benign salivary gland tumours. CT scan and MRI revealed a well-demarcated tumour with an area of necrosis within, with no obvious invasion into surrounding soft tissue and no significant lymphadenopathy. Having high suspicion of a malignant transformation, the tumour was resected with a concurrent modified radical neck dissection. The histopathological examination confirmed a carcinoma ex-pleomorphic adenoma with the myoepithelial malignant component. The patient subsequently received adjuvant radiotherapy. This case demonstrated that CXPA, although rare, can occur in young adults. Pre-operative FNAC and radiological imaging may mimic a pleomorphic adenoma. The presence of recurrent tumours with rapid growth should alarm the clinician about a possible malignant transformation of a benign parotid tumour.
多形性腺瘤癌(CXPA)可主要由良性多形性腺瘤(PA)恶变而来。CXPA大多发生在50至70岁的成年人身上,因此,CXPA在年轻人中并不常见。我们报告了一名 27 岁女性的病例,她曾因多形性腺瘤接受过颌下腺切除术,4 个月来反复出现左侧颌下腺肿物。肿块迅速增大,并伴有偶尔的刺痛。检查显示左侧颌下肿物呈多叶状,质地坚硬,上覆皮肤无变化。通过传统和超声引导技术进行了两次 FNAC 检查,结论均为良性唾液腺肿瘤。CT 扫描和核磁共振成像显示肿瘤界限清楚,内部有坏死区,未明显侵犯周围软组织,无明显淋巴结肿大。在高度怀疑肿瘤恶变的情况下,对肿瘤进行了切除,同时进行了改良根治性颈部清扫术。组织病理学检查证实该肿瘤为前乳头状腺瘤癌,伴有肌上皮恶性成分。患者随后接受了辅助放疗。该病例表明,CXPA 虽然罕见,但可发生在年轻人身上。术前 FNAC 和放射成像可能与多形性腺瘤相似。如果肿瘤复发且生长迅速,临床医生应警惕良性腮腺肿瘤可能发生恶变。
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引用次数: 0
Effect of COVID-19 on peripheral and central hearing abilities COVID-19 对外周和中枢听力能力的影响
Pub Date : 2024-01-24 DOI: 10.1186/s43163-024-00567-8
Rohit Bhattacharyya, Sushmitha S. Upadhya, Prashanth Prabhu
COVID-19 has caused various implications on physical and mental health of human beings. It included several symptoms involving the auditory vestibular system. This study aims to investigate the impact of active COVID-19 infection on central and peripheral auditory pathways. Two groups of subjects were involved in the research: Group I consisted of 45 individuals with no history of COVID-19, while Group II included 41 individuals who were diagnosed with COVID-19 through RT-PCR testing. The audiological battery used in this study included Pure tone audiometry, Digit in Noise test, Dichotic CV test, and Pitch pattern test, all of which were administered online. Testing was conducted in two phases for both groups. Phase 1 testing took place within the first 7 days of a positive RT-PCR result, while Phase 2 testing occurred within a week of a negative RT-PCR test. Additionally, participants completed a questionnaire to provide information on general health conditions and their otological symptoms. The results from Phase 1 testing revealed that Group II exhibited statistically lower scores in all the audiological tests compared to Group I (control group). However, during Phase 2 testing, this significant difference was no longer observed between both groups. Based on the findings, it can be inferred that the audiological pathway was compromised during the active infection stage of COVID-19. Therefore, this study highlights changes in performance concerning tests that assess the central auditory system during the infection period. SH/IRB/RP/24. Registered 12 January 2021.
COVID-19 对人类的身心健康造成了各种影响。其中包括一些涉及听觉前庭系统的症状。本研究旨在调查 COVID-19 活动性感染对中枢和外周听觉通路的影响。研究涉及两组受试者:第一组包括 45 名无 COVID-19 感染史的受试者,第二组包括 41 名通过 RT-PCR 检测确诊感染 COVID-19 的受试者。本研究采用的听力测试包括纯音测听、噪声中数字测试、二分CV测试和音高模式测试,所有测试均在线进行。两组测试均分两个阶段进行。第一阶段测试在 RT-PCR 检测结果呈阳性的头 7 天内进行,而第二阶段测试则在 RT-PCR 检测结果呈阴性的一周内进行。此外,参与者还填写了一份问卷,以提供有关一般健康状况和耳科症状的信息。第 1 阶段测试结果显示,与第 I 组(对照组)相比,第 II 组在所有听力测试中的得分均低于第 I 组。然而,在第二阶段测试中,两组之间不再存在显著差异。根据研究结果可以推断,在 COVID-19 的活跃感染阶段,听觉通路受到了损害。因此,本研究强调了感染期间评估中枢听觉系统的测试成绩的变化。SH/IRB/RP/24。2021 年 1 月 12 日注册。
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引用次数: 0
The use of Arabic Language Sample Analysis as a screening tool in kindergarten Egyptian bilingual children 将阿拉伯语抽样分析法用作幼儿园埃及双语儿童的筛查工具
Pub Date : 2024-01-24 DOI: 10.1186/s43163-024-00569-6
Dalia Mostafa Osman, Asmaa Ahmed Abdel Hamid, Samar Maged, Aisha Fawzy Abdel Hady
Language sample analysis is a naturalistic method used for measuring child’s expressive language abilities. It is used in case of difficulty in direct interaction in remote places or pandemics. The aim of this study is to evaluate the use of a language sample analysis as an easy applicable screening tool for narrative ability in kindergarten Egyptian bilingual children in order to reach a better understanding of their language profile. Subjects and methods: 150 bilingual Egyptian preschool male and female children exposed to Arabic and English languages were included and divided into two groups according to their age. All were subjected to the BEA-LSA narration assessment including macrostructure, microstructure items, and conversation assessment including verbal and nonverbal items. The results revealed that bilingual children showed better performance in English than Arabic in most of the narration and conversation tasks. However, there was equal development between both age groups in English language regarding temporality, connectives, and reference clarity. The older age group showed higher code switching than younger age group and code switching occurred more from Arabic to English language. Both age groups bilingual children showed better frequency of words and mean length of utterance in narration. While in conversation, both age groups showed better type token ratio. Language sample analysis showed good test–retest reliability. Language sample analysis could identify the characteristic profile of bilingual kindergarten Egyptian children and was a reliable method to analyze both narration and conversation skills of bilingual children.
语言样本分析是一种用于测量儿童语言表达能力的自然方法。它适用于在偏远地区或流行病地区难以进行直接交流的情况。本研究旨在评估语言样本分析作为一种简便适用的筛选工具在幼儿园埃及双语儿童叙事能力中的应用,以便更好地了解他们的语言状况。研究对象和方法:研究对象包括 150 名学习阿拉伯语和英语的埃及学龄前男女双语儿童,并根据他们的年龄分为两组。所有儿童都接受了 BEA-LSA 叙事评估(包括宏观结构和微观结构项目)和会话评估(包括口头和非口头项目)。结果显示,在大多数叙述和会话任务中,双语儿童的英语表现优于阿拉伯语。不过,在时间性、连接词和参照物清晰度方面,两个年龄组的儿童在英语方面的发展相同。年龄较大的儿童比年龄较小的儿童有更多的语码转换,从阿拉伯语到英语的语码转换也更多。在叙述中,两个年龄组的双语儿童都表现出较高的词汇频率和平均语篇长度。在会话中,两个年龄组的儿童都表现出较好的标记类型比例。语言样本分析显示出良好的测试-再测试可靠性。语言样本分析可以确定埃及幼儿园双语儿童的特征,是分析双语儿童叙述和会话技能的可靠方法。
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引用次数: 0
The effects of music listening time with headphones on hearing thresholds among the young population 用耳机听音乐的时间对年轻人听力阈值的影响
Pub Date : 2024-01-24 DOI: 10.1186/s43163-024-00574-9
Hülya Osmanoğlu, Handan Turan Dizdar, Azize Arzu Koçyiğit
Today, young people who listen to loud music, especially through headphones, are at an extremely high risk of noise-induced hearing loss. The aim of this study was to investigate how young people’s listening habits affect their hearing thresholds. A total of 88 young adults between the ages of 18 and 25 took part in the study, 44 of whom listened to music through headphones while the others did not. The control group was exposed to white noise at 55–65 dB with the Interacoustic AC 40 Hybrid Audiometer, and people who did not use headphones and said they were not exposed to higher levels of sound than the given sample were included in the study. Participants were given a survey to assess their music listening preferences. One hundred twenty-five to 18,000 Hz air conduction hearing thresholds were assessed for all participants. When the pure tone thresholds of the groups were compared, the independent t-test showed that the thresholds of the study group were significantly worse than those of the control group. Bilaterally in the 4000 Hz band and for the left ear in the 6000 Hz band (p < 0.05). There were also significant differences between the groups in the 14,000 Hz and 16,000 Hz bands in the right ear and the 14,000 Hz, 16,000 Hz, and 18,000 Hz bands in the left ear (p < 0.05). Twenty-two participants reported listening to music at a high level, 16 participants at a moderate level, and 6 participants at a very high level. Although the hearing thresholds of the study group were worse than those of the control group in the 4000 Hz, 6000 Hz, 14,000 Hz, 16,000 Hz, and 18,000 Hz bands, the hearing thresholds of both groups were still within the hearing range and could be classified as normal. It should be remembered that hearing will deteriorate if a person listens to loud or very loud music continuously through headphones. The public, especially young people, should be made aware of this.
如今,年轻人听嘈杂的音乐,尤其是通过耳机听音乐,极有可能导致噪音引起的听力损失。这项研究旨在调查年轻人的听力习惯如何影响他们的听阈。共有 88 名 18 至 25 岁的年轻人参加了这项研究,其中 44 人通过耳机聆听音乐,其他人则没有。对照组使用 Interacoustic AC 40 混合式听力计暴露在 55-65 分贝的白噪声中,没有使用耳机且表示自己没有暴露在比给定样本更高水平的声音中的人也被纳入了研究范围。研究人员向参与者发放了一份调查问卷,以评估他们的音乐聆听偏好。对所有参与者的 125 至 18,000 赫兹气导听力阈值进行了评估。在比较各组的纯音阈值时,独立 t 检验表明,研究组的阈值明显低于对照组。双侧在 4000 赫兹频段和左耳在 6000 赫兹频段的阈值均低于对照组(P < 0.05)。在右耳的 14,000 Hz 和 16,000 Hz 频段,以及左耳的 14,000 Hz、16,000 Hz 和 18,000 Hz 频段,两组之间也存在明显差异(P < 0.05)。22 名参与者表示听音乐的水平较高,16 名参与者表示听音乐的水平中等,6 名参与者表示听音乐的水平很高。虽然研究组在 4000 赫兹、6000 赫兹、14000 赫兹、16000 赫兹和 18000 赫兹频段的听阈比对照组差,但两组的听阈仍在听力范围内,可归类为正常。需要提醒的是,如果一个人通过耳机连续收听大音量或非常大音量的音乐,听力就会下降。应让公众,尤其是年轻人了解这一点。
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引用次数: 0
Optimum stimulus for eliciting masseter vestibular-evoked myogenic potential: a comparative exploration with three different acoustic stimuli 激发颌间肌前庭诱发肌原电位的最佳刺激:三种不同声音刺激的比较研究
Pub Date : 2024-01-23 DOI: 10.1186/s43163-024-00570-z
Aishwarya Nagarajan, Vinayagar Pazhani Thirusangu, Gunasekaran Mohanlal, Sujeet Kumar Sinha
To compare the EMG rectified amplitude, absolute latencies, interpeak interval, and Interaural asymmetry parameters of masseter vestibular-evoked myogenic potential (mVEMP) elicited using clicks, 500 Hz tone bursts, and 500 Hz NB CE-chirps. Twenty-five young healthy adults in the age range of 18–27 years participated for the study. mVEMP was recorded using three different acoustic stimuli i.e., clicks, 500 Hz tone bursts, and 500 Hz NB CE-chirps. mVEMP was recorded at an intensity of 125 dB peSPL with 5.1/s repetition rate. The potentials were recorded ipsilaterally using zygomatic electrode montage and were filtered between 0.1 and 3000 Hz. EMG rectification of the responses was made prior to analysis. The latencies of P1 and N1 were significantly earlier for chirps then followed by click and tone bursts. The EMG rectified amplitude was significantly larger for the potentials obtained using chirps followed by tone bursts and then the clicks. Masseter VEMP obtained using chirps had significantly larger interpeak interval than tone bursts and clicks. The mean amplitude asymmetry ratio was greater in the potentials obtained using chirps than the other two stimuli. The present study reveals that 500 Hz NB CE-chirps tend to produce mVEMP with larger response amplitude and earlier latencies and thus are considered better and constructive stimuli compared to clicks and tone bursts.
比较使用单击、500 Hz音爆和500 Hz NB CE-chirps引起的颌间肌前庭诱发肌源性电位(mVEMP)的肌电信号整流振幅、绝对潜伏期、峰间时间间隔和耳内不对称参数。mVEMP 在 125 dB peSPL 的强度和 5.1/s 的重复率下记录。使用颧电极单体记录同侧电位,并在 0.1 至 3000 Hz 之间进行滤波。分析前对反应进行 EMG 整流。P1 和 N1 的潜伏期明显早于鸣叫,其次是单击和音爆。使用鸣音获得的肌电图整流振幅明显更大,然后是音爆,最后是单击。使用 "啾啾 "声获得的肌肉肌电图的峰间间隔明显大于 "嗒嗒 "声和 "嗒嗒 "声。使用 "啾啾 "声获得的电位的平均振幅不对称比大于其他两种刺激。本研究表明,500 Hz NB CE-chirps往往能产生反应幅度更大、潜伏期更早的mVEMP,因此与单击声和音爆相比,被认为是更好的建设性刺激。
{"title":"Optimum stimulus for eliciting masseter vestibular-evoked myogenic potential: a comparative exploration with three different acoustic stimuli","authors":"Aishwarya Nagarajan, Vinayagar Pazhani Thirusangu, Gunasekaran Mohanlal, Sujeet Kumar Sinha","doi":"10.1186/s43163-024-00570-z","DOIUrl":"https://doi.org/10.1186/s43163-024-00570-z","url":null,"abstract":"To compare the EMG rectified amplitude, absolute latencies, interpeak interval, and Interaural asymmetry parameters of masseter vestibular-evoked myogenic potential (mVEMP) elicited using clicks, 500 Hz tone bursts, and 500 Hz NB CE-chirps. Twenty-five young healthy adults in the age range of 18–27 years participated for the study. mVEMP was recorded using three different acoustic stimuli i.e., clicks, 500 Hz tone bursts, and 500 Hz NB CE-chirps. mVEMP was recorded at an intensity of 125 dB peSPL with 5.1/s repetition rate. The potentials were recorded ipsilaterally using zygomatic electrode montage and were filtered between 0.1 and 3000 Hz. EMG rectification of the responses was made prior to analysis. The latencies of P1 and N1 were significantly earlier for chirps then followed by click and tone bursts. The EMG rectified amplitude was significantly larger for the potentials obtained using chirps followed by tone bursts and then the clicks. Masseter VEMP obtained using chirps had significantly larger interpeak interval than tone bursts and clicks. The mean amplitude asymmetry ratio was greater in the potentials obtained using chirps than the other two stimuli. The present study reveals that 500 Hz NB CE-chirps tend to produce mVEMP with larger response amplitude and earlier latencies and thus are considered better and constructive stimuli compared to clicks and tone bursts.","PeriodicalId":501131,"journal":{"name":"The Egyptian Journal of Otolaryngology","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139555298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Speech auditory brainstem responses (s-ABRs) as a new approach for the assessment of speech sounds coding 语音听觉脑干反应(s-ABRs)是评估语音编码的一种新方法
Pub Date : 2024-01-22 DOI: 10.1186/s43163-024-00562-z
Hagar Ahmed Elsayed, Ebtessam Hamed Nada, Dalia Helal Galhoum, Nadia Mohamed Elnabtity
The evoked auditory brainstem response (EABR) is an objective electrophysiological test used to assess the brainstem’s auditory neural activity. Speech ABR (s-ABR) testing using verbal stimuli gives more important details about how the brainstem processes speech inputs which enables the detection of auditory processing impairments that do not manifest in click-provoked ABR. The use of speech syllables in the s-ABR reveals an important brainstem function that plays a crucial part in reading development and phonologic achievement which is an assessment of speech syllables. The syllable /da/ is often utilized in s-ABR measurement being a global syllable that can be tested in many nations with effective experimental confidence. The speech ABR is an objective, unbiased, quick test. It can be used to differentiate between many conditions such as auditory processing disorders (APD), specific language impairment (SLI), and children with academic challenges.
诱发听性脑干反应(EABR)是一种客观的电生理测试,用于评估脑干的听觉神经活动。使用言语刺激进行的言语诱发听性脑干反应(s-ABR)测试能提供更多有关脑干如何处理言语输入的重要细节,从而检测出在点击诱发听性脑干反应中没有表现出来的听觉处理障碍。s-ABR 中语音音节的使用揭示了在阅读发展和语音成就中起关键作用的一项重要脑干功能,即对语音音节的评估。音节 /da/ 经常被用于 s-ABR 测量,因为它是一个全球性的音节,可以在许多国家进行测试,并具有有效的实验信心。语音 ABR 是一种客观、公正、快速的测试。它可用于区分多种疾病,如听觉处理障碍 (APD)、特殊语言障碍 (SLI) 和学习有困难的儿童。
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引用次数: 0
Correlation between tympanometric findings and adenoid hypertrophy among children without hearing loss in tertiary care hospital 三级医院无听力损失儿童的鼓室测量结果与腺样体肥大之间的相关性
Pub Date : 2024-01-22 DOI: 10.1186/s43163-024-00568-7
K. P. Basavaraju, S. K. Ranjani, V. Sri Vaibhava, Sushmita Sulhyan
Adenoid hyperplasia is a common cause of nasal obstruction in children. Chronic infection and hypertrophy result in mouth breathing, snoring, sleep apnoea, hyponasality, sinusitis, and otitis media with effusion (OME). Some children with adenoid hypertrophy have OME in spite of having no complaints of hearing loss. Untreated OME may adversely affect the speech and intellectual development of the child. Aim To determine whether there is a correlation between tympanometric findings and various radiological and endoscopic grades of adenoid hypertrophy. To propose a combination of radiological and/or endoscopic assessment of adenoids and tympanometry as a screening program in patients with suspicion of adenoid hypertrophy. Materials and methods One hundred children, presenting with one or more complaints of upper airway obstruction (UAO), suggestive of adenoid hypertrophy, without a history of hearing loss, to the OPD, were chosen for the study. X-ray nasopharynx soft tissue lateral view was done for all patients. Rigid diagnostic nasal endoscopy with 0° endoscope was conducted in only children who were cooperative and with parental consent. Tympanometry was carried out for all patients and plotted on tympanograms. Results In our study, the mean age of children is 9.43 ± 2.430 years with gender distribution being 57% males and 43% females. The majority of children tend to present with nasal obstruction (100%), mouth breathing (83%), and snoring (56%). On both radiological and endoscopic evaluation of adenoids and correlation with tympanogram, a significantly higher number of patients with Grade 1 adenoids have a type A curve, while a significantly higher number of grade 3 adenoids patients have a type B curve and type C is significantly more prevalent in grade 2 and grade 4 adenoids (p < 0.05). Conclusion In our study, adenoid size as measured from both adenoid X-ray and adenoid endoscopy, showed a significant association with the presence of middle ear effusion and also with eustachian tube dysfunction. This helps in early detection, prior to the development of hearing loss, making it easy to plan early intervention, and curbing the possibility of aggravation of the condition and occurrence of complications.
腺样体增生是导致儿童鼻塞的常见原因。慢性感染和腺样体肥大会导致口呼吸、打鼾、睡眠呼吸暂停、鼻塞、鼻窦炎和中耳炎伴渗出(OME)。有些腺样体肥大患儿虽然没有听力损失的症状,但却患有中耳积液。OME 如不及时治疗,可能会对儿童的言语和智力发育造成不良影响。目的 确定鼓室测量结果与腺样体肥大的各种放射学和内窥镜分级之间是否存在相关性。建议将腺样体的放射学和/或内窥镜评估与鼓室测量相结合,作为怀疑腺样体肥大患者的筛查方案。材料和方法 本次研究选择了 100 名在门诊部就诊、有一次或多次上气道阻塞(UAO)主诉、提示腺样体肥大、无听力损失病史的儿童。对所有患者进行鼻咽软组织侧视 X 光检查。仅对合作并征得家长同意的儿童使用 0° 内窥镜进行鼻内窥镜硬性诊断检查。对所有患者进行鼓室测量并绘制鼓室图。结果 在我们的研究中,儿童的平均年龄为(9.43 ± 2.430)岁,性别分布为男性占 57%,女性占 43%。大多数患儿往往伴有鼻塞(100%)、口呼吸(83%)和打鼾(56%)。通过放射学和内窥镜对腺样体进行评估,并与鼓室造影相关联,1 级腺样体患者的 A 型曲线明显较多,而 3 级腺样体患者的 B 型曲线明显较多,2 级和 4 级腺样体患者的 C 型曲线明显较多(P < 0.05)。结论 在我们的研究中,通过腺样体 X 光片和腺样体内窥镜检查测量到的腺样体大小与中耳积液和咽鼓管功能障碍有显著关联。这有助于在出现听力损失之前及早发现,便于制定早期干预计划,并遏制病情加重和并发症发生的可能性。
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引用次数: 0
Ectopic upper third molar embedded in a dentigerous cyst of the maxillary sinus: a case report and literature review 嵌入上颌窦齿槽囊肿的异位上第三磨牙:病例报告和文献综述
Pub Date : 2024-01-19 DOI: 10.1186/s43163-024-00564-x
Raid M. Al-Ani, Tahrir N. Aldelaimi, Afrah A. Khalil, Suzan M. Abdulkareem
Dentigerous cysts are the second most common form of a developmental cyst. These cysts might be the cause of ectopic teeth. Dentigerous cysts associated with ectopic teeth in the maxillary sinus are seldom seen in clinical practice. We reported a 23-year-old woman who presented with nasal obstruction and facial pain on the left side 4 months ago. Three courses of antibiotics and analgesia were prescribed for her without improving the presenting features. Furthermore, extraction of the left upper second premolar and second molar, but the condition persisted. An orthopantogram and computerized tomography scan revealed the ectopic position of the left third upper molar tooth, which was embedded in a cystic lesion occupying the whole maxillary sinus. Removal of the cystic lesion with the ectopic tooth was performed with a Caldwell-Luc procedure. The histopathological evaluation confirmed the diagnosis of a dentigerous cyst. The presenting symptoms were resolved following surgery with no intra- or postoperative complications. We are reporting another case of a dentigerous cyst occupying the whole left maxillary sinus with an ectopic left third upper molar tooth. Reporting such a case will enrich the literature regarding this rare clinical entity.
牙源性囊肿是第二种最常见的发育囊肿。这些囊肿可能是导致异位牙的原因。与上颌窦异位牙相关的齿槽囊肿在临床上很少见。我们报告了一名 23 岁女性的病例,她 4 个月前出现鼻塞和左侧面部疼痛。医生为她开了三个疗程的抗生素和镇痛药,但症状并未得到改善。此外,她还拔掉了左上第二颗前臼齿和第二颗臼齿,但病情依然存在。正位图和计算机断层扫描显示,左上第三磨牙位置异位,嵌入占据整个上颌窦的囊性病变中。通过 Caldwell-Luc 手术切除了囊性病变和异位牙齿。组织病理学评估证实了牙源性囊肿的诊断。术后症状消失,无术中、术后并发症。我们报告的是另一例占据整个左上颌窦的齿槽囊肿,并伴有一颗异位的左第三上磨牙。报告这样的病例将丰富有关这种罕见临床实体的文献。
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引用次数: 0
A comparative study of short-term phonatory outcomes in primary cases of early glottic cancer treated with radiotherapy versus laser surgery 放疗与激光手术治疗早期声门癌原发病例短期发音效果比较研究
Pub Date : 2024-01-18 DOI: 10.1186/s43163-024-00565-w
Devender Kumar Gupta, Mahesh Ravunnikutty, Sanajeet Kumar Singh, Rajeev Chugh, Ravi Roy, Sunil Goyal, Himanshu Swami, Bhaumik Patel, Sneha Yadav, Sween Banger
Early-stage glottic carcinomas can be treated with either laser surgery or radiotherapy. Both approaches have demonstrated similar cure rates. However, the question of which modality is superior in terms of voice outcomes remains a topic of debate. In our study, we conducted a comparison of short-term phonatory outcomes in patients with primary early glottic cancer who underwent treatment using both modalities. We assessed these outcomes using videostroboscopy and voice analysis software at three time points: immediately following treatment, at 1 month, and at 3 months post-treatment. Voice analysis revealed that laser surgery had a more favorable immediate effect compared to radiotherapy in parameters such as jitter, shimmer, harmonics-to-noise ratio, and fundamental frequency. However, at the 3-month post-treatment mark, both treatment modalities demonstrated similar effects. Additionally, both modalities had comparable effects on maximum phonation time. Videostroboscopy observations showed that mucosal wave forms were more prominent immediately after laser surgery and gradually improved following radiotherapy. Furthermore, patients with incomplete glottic closure experienced recovery after both treatment modalities. Based on the results, there are better outcomes immediately following LS compared to RT. However, after a 3-month period, the outcomes of both treatment modalities become comparable. The treating physicians must consider various factors such as complications, patient-specific considerations, treatment costs, and duration to make informed decisions. A personalized approach considering the individual patient’s circumstances is crucial in achieving optimal results in the management of T1 laryngeal cancer.
早期声门癌可采用激光手术或放射治疗。两种方法的治愈率相似。然而,哪种方法在嗓音效果方面更胜一筹仍是一个争论不休的话题。在我们的研究中,我们比较了接受两种方法治疗的原发性早期声门癌患者的短期发音效果。我们在三个时间点使用视频罗盘镜和嗓音分析软件对这些结果进行了评估:治疗后即刻、治疗后 1 个月和治疗后 3 个月。嗓音分析表明,在抖动、颤动、谐波噪声比和基频等参数方面,激光手术的即时效果比放射治疗更佳。不过,在治疗后 3 个月,两种治疗方式的效果相似。此外,两种模式对最大发音时间的影响也相当。视频旋转镜观察结果显示,激光手术后粘膜波形更加明显,放疗后粘膜波形逐渐改善。此外,声门关闭不全的患者在两种治疗方式后都得到了恢复。根据上述结果,与 RT 相比,LS 术后的即时疗效更好。然而,3 个月后,两种治疗方式的效果不相上下。治疗医生必须考虑各种因素,如并发症、患者的具体情况、治疗费用和持续时间,才能做出明智的决定。在治疗 T1 喉癌时,考虑患者个体情况的个性化方法对于取得最佳治疗效果至关重要。
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引用次数: 0
Vitamin D profile in autism spectrum disorder children and its relation to the disease severity 自闭症谱系障碍儿童的维生素 D 含量及其与疾病严重程度的关系
Pub Date : 2024-01-18 DOI: 10.1186/s43163-024-00573-w
Amira Mansour, Ayman Amer, Ali Sobh, Maysaa Zaki, Tamer Abou-Elsaad
The study aimed to investigate whether vitamin D deficiency is a common finding in autism spectrum disorder (ASD) children and whether such deficiency is related to ASD severity and language age or not. A cross-sectional observational study was conducted on ASD children aged 2-6 years. The participants were 80 Egyptian children with ASD. All participants were assessed using DSM-V, the Childhood Autism Rating Scale (CARS), language assessment, and assessment of serum vitamin D using ADVIA Centaur Vit D assay. About 63.8% of ASD children have vitamin D insufficiency, 28.8 % have vitamin D deficiency, and 7.4% have normal serum levels. No correlation was found between serum vitamin D and language age (r = -0.085, P = 0.451), DSM 5 severity levels (r = 0.015, P= 0.894), and CARS scores (r= 0.075, P= 0.511). ASD children have lower serum vitamin D levels, which may be one of the environmental factors contributing to ASD development in genetically susceptible individuals, and its correction may be helpful as adjuvant therapy for ASD.
该研究旨在调查自闭症谱系障碍(ASD)儿童是否普遍缺乏维生素D,以及这种缺乏是否与自闭症谱系障碍的严重程度和语言年龄有关。该研究针对 2-6 岁的自闭症谱系障碍儿童开展了一项横断面观察研究。研究对象为 80 名患有 ASD 的埃及儿童。所有参与者均接受了 DSM-V、儿童自闭症评定量表(CARS)、语言评估以及使用 ADVIA Centaur 维生素 D 检测仪进行的血清维生素 D 评估。约 63.8% 的自闭症儿童维生素 D 不足,28.8% 的自闭症儿童维生素 D 缺乏,7.4% 的自闭症儿童血清维生素 D 水平正常。血清维生素 D 与语言年龄(r = -0.085,P = 0.451)、DSM 5 严重程度(r = 0.015,P = 0.894)和 CARS 评分(r = 0.075,P = 0.511)之间没有相关性。ASD儿童的血清维生素D水平较低,这可能是导致遗传易感个体发生ASD的环境因素之一,其纠正可能有助于ASD的辅助治疗。
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The Egyptian Journal of Otolaryngology
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