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Strategic investment and program effectiveness: a roadmap to ending AIDS in Bangladesh by 2030 战略投资与计划成效:到 2030 年在孟加拉国消除艾滋病的路线图
Pub Date : 2024-09-10 DOI: 10.1080/09540121.2024.2397132
Mohammed Nazmul Huq, Saima Khan, Sabina Yasmin, Md. Moyazzem Hossain
The journey towards ending AIDS epidemic in Bangladesh by 2030 is ambitious yet achievable. Although Bangladesh has always had a low rate of HIV among its general population, it remains one of seve...
到 2030 年在孟加拉国消除艾滋病疫情的征程雄心勃勃,但也是可以实现的。尽管孟加拉国普通人群中的艾滋病毒感染率一直很低,但它仍然是世界上少数几个艾滋病流行国家之一。
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引用次数: 0
Exploring the impact of coping self-efficacy on psychological distress among violence-affected people living with HIV. 探讨受暴力影响的艾滋病病毒感染者的自我应对能力对心理压力的影响。
Pub Date : 2024-05-16 DOI: 10.1080/09540121.2024.2345688
Kara Steele, Stephanie Tokarz, E. Felker-Kantor, Katherine P Theall, Gretchen A Clum
ABSTRACTThis study examines the relationship between coping self-efficacy, concurrent stress, and psychological distress (borderline/clinical anxiety, depression, and PTSD symptoms) among people living with HIV (PLWH). Using data from a cohort of PLWH living in a southern peri-urban area, logistic regression analyses were conducted to determine the effects of self-reported coping self-efficacy on psychological distress in a sample of 85 violence-affected PLWH. We also tested the moderating effect of coping self-efficacy on the concurrent stress-psychological distress relationships. In adjusted models, coping self-efficacy was significantly associated with symptoms of anxiety and PTSD, but not depressive symptoms. Findings indicate that high coping self-efficacy may reduce one's likelihood of anxiety and PTSD symptoms among PLWH.
摘要本研究探讨了艾滋病毒感染者(PLWH)的自我应对能力、并发压力和心理困扰(边缘/临床焦虑、抑郁和创伤后应激障碍症状)之间的关系。利用生活在南部近郊地区的艾滋病病毒感染者队列中的数据,我们对 85 名受暴力影响的艾滋病病毒感染者样本进行了逻辑回归分析,以确定自我报告的应对自我效能对心理困扰的影响。我们还测试了应对自我效能感对同时存在的压力-心理困扰关系的调节作用。在调整后的模型中,应对自我效能与焦虑和创伤后应激障碍症状有显著相关性,但与抑郁症状无关。研究结果表明,高应对自我效能感可能会降低 PLWH 患者出现焦虑和创伤后应激障碍症状的可能性。
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引用次数: 0
An exploratory study of community violence and HIV care engagement among Black gay and bisexual men. 黑人男同性恋和双性恋者中社区暴力和艾滋病护理参与情况的探索性研究。
Pub Date : 2024-04-22 DOI: 10.1080/09540121.2024.2331221
Dexter Voisin, Lois M Takahashi, Jennifer L Walsh, Wayne DiFranceisco, Anthony Johnson, Andrea Dakin, Nora Bouacha, Khalil Brown, Katherine Quinn
This study examined the relationship between exposure to community violence and HIV care engagement among 107 Black gay or bisexual men living with HIV in Chicago. Measures assessed the importance of demographic covariates (age, annual income, health insurance status, and years living with HIV), community violence exposures, mental health, social support, in explaining variations in missed doses of antiretroviral therapy (ART) medication and missed HIV care appointments. Results showed that participants who reported higher rates of exposure to community violence were two times more likely to have missed ART doses and HIV care appointments. Participants who reported depression scores were two times more likely to have greater non-ART adherence. Finally, older participants were more likely to report fewer missed ART doses. More research is needed to clarify the mechanisms between age or depression and ART adherence given community violence exposure. Health care providers should screen for depression when attempting to promote better ART adherence and keeping HIV care appointments for Black gay and bisexual men living with HIV. Younger Black gay and bisexual men living with HIV may be more vulnerable than older men for missed ART doses and may require additional screening and follow-up.
本研究调查了芝加哥 107 名感染 HIV 的黑人男同性恋或双性恋者中社区暴力暴露与 HIV 护理参与之间的关系。这些措施评估了人口统计学协变量(年龄、年收入、医疗保险状况和感染 HIV 的年数)、社区暴力暴露、心理健康和社会支持在解释抗逆转录病毒疗法(ART)药物漏服和 HIV 护理预约缺席的变化方面的重要性。结果表明,报告遭受社区暴力比例较高的参与者错过抗逆转录病毒疗法药物剂量和艾滋病护理预约的可能性要高出两倍。报告患有抑郁症的参与者不坚持抗逆转录病毒疗法的可能性要高出两倍。最后,年龄较大的参与者更有可能报告较少错过抗逆转录病毒疗法剂量。需要进行更多的研究来阐明年龄或抑郁与接触社区暴力后坚持抗逆转录病毒疗法之间的机制。医疗服务提供者在试图促进黑人男同性恋和双性恋感染者更好地坚持抗逆转录病毒疗法和遵守艾滋病护理预约时,应筛查抑郁症。年轻的黑人男同性恋和双性恋感染者可能比年长者更容易错过抗逆转录病毒疗法的剂量,因此可能需要额外的筛查和随访。
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引用次数: 0
Antiretroviral adherence among people living with HIV during the postpartum period: a retrospective cohort study at a PMTCT reference center in Rio de Janeiro before and during the COVID-19 pandemic. 产后艾滋病毒感染者坚持使用抗逆转录病毒疗法的情况:在 COVID-19 大流行之前和期间,在里约热内卢一家预防母婴传播参考中心进行的一项回顾性队列研究。
Pub Date : 2024-04-22 DOI: 10.1080/09540121.2024.2343590
Fellipe Pinheiro Lattanzi, Maria Isabel Fragoso da Silveira Gouvêa, Maria de Lourdes Benamor Teixeira, Trevon Fuller, Maria Clara Macêdo Pinheiro Sodré, Adriana Ferreira Medeiros, Clarisse da Silveira Bressan, Mariza de Matos Salgueiro, Camile Medeiros Braga, Marcelo Gouvêa, Patrícia Amorim da Silva, Wallace Mendes-Silva, Elaine Cristina Souza, Marília Santini de Oliveira, L. Ceci, E. C. João
Despite success in achieving viral suppression during pregnancy in people living with HIV (PLWH), postpartum adherence remains a challenge. We aimed to describe rates of adherence at a Prevention of Mother-to-Child HIV Transmission (PMTCT) Center before and during the COVID-19 pandemic. This study was conducted from a cohort of PLWH who received prenatal care and were virally suppressed near delivery. We tracked combined antiretroviral therapy (cART) pickups for 12 months and HIV viral load (VL) from 2 to 12 months after delivery. We defined flexible adherence as a monthly pickup of cART and strict adherence as also having VL < 200 copies/mL and at least one maternal HIV VL between two and twelve months postpartum. Pre-pandemic was defined as delivery from March 2017-February 2019 and pandemic as March 2020-February 2022. During the study, 1119 PLWH were followed, and 965 (86%) were suppressed near delivery. There were 511 pre-pandemic and 290 pandemic participants. Adherence rates were 66/511 (13%) and 38/290 (13%), respectively. During the pandemic, more participants conceived using cART and were undetectable at the start of prenatal care; nevertheless, postpartum adherence was no better than pre-pandemic underscoring the need to improve strategies for adherence specific to this subset of PLWH in the postpartum period.
尽管艾滋病病毒感染者(PLWH)在怀孕期间成功实现了病毒抑制,但产后坚持治疗仍是一项挑战。我们旨在描述在 COVID-19 大流行之前和期间,预防母婴传播(PMTCT)中心的依从率。这项研究的对象是接受产前护理并在临近分娩时病毒得到抑制的艾滋病毒感染者。我们跟踪了 12 个月的联合抗逆转录病毒疗法(cART)接种情况和产后 2 至 12 个月的 HIV 病毒载量(VL)。我们将灵活坚持治疗定义为每月接受一次 cART 治疗,将严格坚持治疗定义为 VL < 200 copies/mL,并且在产后 2 到 12 个月期间至少有一次产妇 HIV VL 检测。大流行前定义为 2017 年 3 月至 2019 年 2 月期间分娩,大流行为 2020 年 3 月至 2022 年 2 月。研究期间,对 1119 名艾滋病毒感染者进行了随访,其中 965 人(86%)在临近分娩时得到了抑制。大流行前有 511 名参与者,大流行时有 290 名参与者。坚持率分别为 66/511(13%)和 38/290(13%)。在大流行期间,有更多的参与者使用 cART 受孕,并且在产前护理开始时检测不到病毒;然而,产后的依从性并不比大流行前好,这突出表明有必要改进针对这一群体的产后依从性策略。
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引用次数: 0
What drives older men who have sex with men in China away from AIDS information? 是什么驱使中国的老年男性同性恋者远离艾滋病信息?
Pub Date : 2024-04-22 DOI: 10.1080/09540121.2024.2343767
Xudong Gao, Feng Ding, Mei Wang, Chan Kong
A worrying phenomenon has emerged recently: more people are deliberately avoiding rather than seeking information regarding acquired immunodeficiency syndrome (AIDS). This is the first study to explore behaviors related to AIDS information avoidance and the potential influential factors among older men who have sex with men (MSM). We enrolled 11 older MSM from Wuhan, the largest city in central China, from January to March 2023 using a phenomenological method. This qualitative research was conducted using face-to-face semi-structured interviews. AIDS information avoidance was commonly observed among the respondents. Behaviors related to AIDS information avoidance included avoiding AIDS-related information, ignoring known AIDS information, and avoiding medical care. The main factors associated with AIDS information avoidance included information overload, high-risk sexual behaviors, over-optimism, fear of disclosure, and age. China should provide AIDS information in a manner suitable for older MSM, pay more attention to MSM over the age of 70 years, those who are not open about their sexual orientation and those who are too optimistic, and strengthen the censorship of AIDS information.
最近出现了一个令人担忧的现象:越来越多的人有意回避而不是寻求有关获得性免疫缺陷综合症(艾滋病)的信息。这是第一项在老年男男性行为者(MSM)中探讨与回避艾滋病信息相关的行为及潜在影响因素的研究。我们采用现象学方法,于 2023 年 1 月至 3 月在中国中部最大的城市武汉招募了 11 名老年男男性行为者。这项定性研究采用了面对面的半结构化访谈。受访者中普遍存在回避艾滋病信息的现象。与艾滋病信息回避相关的行为包括回避艾滋病相关信息、忽视已知的艾滋病信息以及逃避医疗。与艾滋病信息回避相关的主要因素包括信息超载、高危性行为、过度乐观、害怕公开和年龄。中国应该以适合老年男男性行为者的方式提供艾滋病信息,更多地关注 70 岁以上、性取向不公开和过于乐观的男男性行为者,并加强对艾滋病信息的审查。
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引用次数: 0
Swiping right on PrEP: a qualitative study of MSM preferences for PrEP public health messaging on dating apps. 向右滑动 PrEP:关于 MSM 对约会应用程序上 PrEP 公共卫生信息偏好的定性研究。
Pub Date : 2024-04-22 DOI: 10.1080/09540121.2024.2343761
Matthew A. Adan, Christina Psaros, Grace Chamberlin, Danielle Zionts, Surabhi L. Iyer, Laura Platt, Mairead Day Lopes, Susana Medeiros, Catherine O’Connor, Ingrid V. Bassett, Kevin L. Ard
Men who have sex with men (MSM) are disproportionately affected by HIV. Given that over 70% of MSM meet sexual partners via dating apps, such apps may be an effective platform for promoting HIV pre-exposure prophylaxis (PrEP) use. We aimed to describe preferences among MSM for PrEP advertisements displayed on dating apps. We conducted individual in-depth interviews with 16 MSM recruited from a mobile sexual health unit in Boston, Massachusetts. Two focus groups were also held: one with mobile unit staff (N = 3) and one with mobile unit users (N = 3). Content analysis was used to identify themes related to advertisement content and integration with app use. Mean participant age was 28 (SD 6.8); 37% identified as White and 63% as Latinx. 21% of interviews were conducted in Spanish. Preferences were organized around four themes: (1) relevant and relatable advertisements, (2) expansion of target audiences to promote access, (3) concise and captivating advertisements, and (4) PrEP advertisements and services as options, not obligations. MSM are supportive of receiving information about PrEP on dating apps, but feel that existing advertisements require modification to better engage viewers. Dating apps may be an underutilized tool for increasing PrEP awareness and knowledge among MSM.
男男性行为者(MSM)感染艾滋病毒的比例过高。鉴于超过 70% 的男男性行为者通过交友应用程序结识性伴侣,此类应用程序可能是推广使用艾滋病暴露前预防(PrEP)的有效平台。我们旨在描述男男性行为者对约会应用程序上展示的 PrEP 广告的偏好。我们对从马萨诸塞州波士顿市一家流动性健康机构招募的 16 名男男性行为者进行了个人深度访谈。我们还举行了两个焦点小组:一个是流动单位的工作人员(3 人),另一个是流动单位的用户(3 人)。内容分析法用于确定与广告内容和应用程序使用整合相关的主题。参与者的平均年龄为 28 岁(标准差 6.8);37% 为白人,63% 为拉丁裔。21%的访谈以西班牙语进行。受访者的偏好围绕四个主题展开:(1) 相关性和亲和力强的广告,(2) 扩大目标受众范围以促进普及,(3) 简明扼要、引人入胜的广告,(4) PrEP 广告和服务是选择而非义务。MSM 支持在约会应用程序上接收有关 PrEP 的信息,但认为需要对现有的广告进行修改,以更好地 吸引观众。在提高 MSM 对 PrEP 的认识和了解方面,约会应用程序可能是一个未得到充分利用的工具。
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引用次数: 0
Heavy alcohol use and the HIV care continuum in Kenya: a population-based study. 肯尼亚的酗酒和艾滋病毒护理连续性:一项基于人口的研究。
Pub Date : 2024-04-22 DOI: 10.1080/09540121.2024.2343587
Edom Wake, J. Rosen
Heavy alcohol use (HAU) can destabilize engagement along the HIV care continuum. Population-based studies assessing associations of HAU with HIV treatment outcomes are lacking, especially in sub-Saharan Africa. We leveraged data from the Kenya Population-based HIV Impact Assessment to identify associations of self-reported HAU, assessed using two items measuring the frequency and quantity of past-year alcohol consumption, with serum biomarkers for HIV serostatus unawareness, antiretroviral therapy (ART) non-use, and HIV viremia (≥1000 RNA copies/mL). Overall and sex-stratified survey-weighted logistic regression with jackknife variance estimation modeled adjusted odds ratios (adjOR) of HIV treatment indicators by HAU. Overall, 1491 persons living with HIV aged 15-64 years (68.4% female) were included. The prevalence of HAU was 8.9% (95% confidence interval [95%CI]: 6.8-11.0%) and was significantly more pronounced in males than females (19.6% vs. 4.0%, p < 0.001). In multivariable analysis, HAU was significantly (p < 0.001) associated with HIV serostatus unawareness (adjOR = 3.65, 95%CI: 2.14-6.23), ART non-use (adjOR = 3.81, 95%CI: 2.25-6.43), and HIV viremia (adjOR = 3.13, 95%CI: 1.85-5.32). Incorporating sex-specific alcohol use screening into HIV testing and treatment services in populations where HAU is prevalent could optimize clinical outcomes along the HIV care continuum.
大量饮酒(HAU)会破坏参与艾滋病治疗的连续性。目前还缺乏基于人群的研究来评估 HAU 与 HIV 治疗结果之间的关系,尤其是在撒哈拉以南非洲地区。我们利用肯尼亚基于人口的 HIV 影响评估数据,确定了自我报告的 HAU(使用两个测量过去一年饮酒频率和数量的项目进行评估)与 HIV 血清状态不知晓、不使用抗逆转录病毒疗法(ART)和 HIV 病毒血症(≥1000 RNA 拷贝/毫升)的血清生物标志物之间的关联。利用杰克刀方差估计法进行的总体和性别分层调查加权逻辑回归模拟了HAU艾滋病治疗指标的调整几率比(adjOR)。总共纳入了 1491 名 15-64 岁的艾滋病病毒感染者(68.4% 为女性)。HAU 患病率为 8.9%(95% 置信区间 [95%CI]:6.8-11.0%),男性患病率明显高于女性(19.6% 对 4.0%,P < 0.001)。在多变量分析中,HAU 与 HIV 血清状态不知晓(adjOR = 3.65,95%CI:2.14-6.23)、抗逆转录病毒疗法不使用(adjOR = 3.81,95%CI:2.25-6.43)和 HIV 病毒血症(adjOR = 3.13,95%CI:1.85-5.32)显著相关(p < 0.001)。在 HAU 流行的人群中,将特定性别的饮酒筛查纳入 HIV 检测和治疗服务中,可优化 HIV 连续护理的临床结果。
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引用次数: 0
Associations between perceived discrimination experiences, treatment adherence self-efficacy, and depressive symptoms among people living with HIV in the Southern United States 美国南部艾滋病毒感染者感知到的歧视经历、坚持治疗的自我效能感与抑郁症状之间的关系
Pub Date : 2024-04-16 DOI: 10.1080/09540121.2024.2341231
Wendy Chu, Cheuk Chi Tam, Sayward Harrison
This study examined associations between perceived discrimination, treatment adherence self-efficacy, and depressive symptoms among people living with HIV (PLHIV) in the Southern United States. Cro...
本研究探讨了美国南部艾滋病病毒感染者(PLHIV)中感知到的歧视、坚持治疗的自我效能感和抑郁症状之间的关系。研究人员...
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引用次数: 0
Impact of the COVID-19 pandemic on mental health and viral suppression among persons living with HIV in western Washington COVID-19 大流行对华盛顿州西部艾滋病毒感染者心理健康和病毒抑制的影响
Pub Date : 2024-04-16 DOI: 10.1080/09540121.2024.2341220
Liying Wang, Francis Slaughter, Anh T. Nguyen, Sarah Smith, Sandeep Prabhu, Kristin Beima-Sofie, Stephaun Wallace, Heidi M. Crane, Jane M. Simoni, Susan M. Graham
The COVID-19 pandemic and social distancing measures elevated stress levels globally, exacerbating mental health challenges for people with HIV (PWH). We examined the effect of COVID-19-related str...
COVID-19大流行和社会疏远措施在全球范围内提高了压力水平,加剧了艾滋病病毒感染者(PWH)的心理健康挑战。我们研究了COVID-19相关措施对HIV感染者心理健康的影响。
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引用次数: 0
Expectations of preventative benefits and risk behaviors in a randomized trial evaluating oral HIV preexposure prophylaxis candidates 评估口服艾滋病暴露前预防候选者的随机试验中对预防益处和风险行为的预期
Pub Date : 2024-04-12 DOI: 10.1080/09540121.2024.2332446
Jeremy Sugarman, Brian W. Weir, Chen Dun, Roy M. Gulick, Timothy J. Wilkin, Kenneth H. Mayer, Marybeth McCauley, Kevin P. Weinfurt
When participants enrolled in an HIV prevention trial hold a preventive misconception (PM) – expectations that experimental interventions will confer protection from HIV infection – they may engage...
当参加艾滋病预防试验的参与者持有预防性误解(PM)--即期望试验干预措施能够保护他们免受艾滋病感染--时,他们可能会参与试验。
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引用次数: 0
期刊
AIDS Care
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