Pub Date : 2025-10-01Epub Date: 2025-06-10DOI: 10.1007/s10396-025-01555-y
Jun Miyazaki, Hideyuki Hayashi, Yuta Torii, Aoi Hamano, Toshiaki Toyota, Yutaka Furukawa
{"title":"Utility of superb microvascular imaging in evaluating intracardiac thrombus in Loeffler endocarditis.","authors":"Jun Miyazaki, Hideyuki Hayashi, Yuta Torii, Aoi Hamano, Toshiaki Toyota, Yutaka Furukawa","doi":"10.1007/s10396-025-01555-y","DOIUrl":"10.1007/s10396-025-01555-y","url":null,"abstract":"","PeriodicalId":50130,"journal":{"name":"Journal of Medical Ultrasonics","volume":" ","pages":"437-438"},"PeriodicalIF":2.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144259299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Purpose: This study aimed to evaluate the effectiveness of the four-section approach using two-dimensional sonography in diagnosing Pierre Robin sequence (PRS) during second-trimester screening.
Methods: A prospective study was conducted on low-risk pregnant women undergoing routine mid-trimester screening. Cases with suspected micrognathia prenatally were included and examined using the four-section approach. Initially, we measured the inferior facial angle (IFA) for fetuses suspected of having micrognathia. Subsequently, in the oblique coronal section via the oral fissure, we examined the continuity of the hard and soft palate line. Finally, dynamic scanning of both the sagittal and coronal sections of the mandible was performed to confirm whether the echogenic tongue was displaced posteriorly. All fetuses diagnosed with PRS were followed up through autopsy and postnatal evaluation.
Results: Forty-three fetuses were initially subjectively suspected of having micrognathia by sonographers. After objective IFA measurement, 25 cases had an IFA < 50°, while 18 had an IFA > 50°. Among the 25 cases with IFA < 50°, we identified 13 cases of PRS with micrognathia, cleft palate (CP), and glossoptosis. However, one case failed to be diagnosed prenatally because it had micrognathia and CP but no glossoptosis. Eleven cases had neither CP nor glossoptosis yet exhibited other malformations. Among the 18 fetuses with IFA > 50°, 15 cases were normal, while three cases had other deformities. In this study cohort, no false-positive results were found. The four-section approach for diagnosing PRS showed a sensitivity of 92.9%, a specificity of 100%, a positive predictive value of 100%, and a negative predictive value of 91.7%.
Conclusion: The four-section method proved highly effective in assessing PRS during second-trimester sonographic scans. The combined evaluation of micrognathia and glossoptosis can remarkably enhance the accuracy of prenatal PRS diagnosis.
目的:本研究旨在评估四段二维超声诊断妊娠中期皮埃尔·罗宾序列(Pierre Robin sequence, PRS)的有效性。方法:对低危孕妇进行常规妊娠中期筛查进行前瞻性研究。产前疑似小颌畸形的病例被纳入并使用四段式方法进行检查。最初,我们测量了怀疑患有小颌畸形的胎儿的下面角(IFA)。随后,在斜冠状面经口裂,我们检查了软硬腭线的连续性。最后,对下颌骨矢状面和冠状面进行动态扫描,以确定回声舌是否向后移位。所有诊断为PRS的胎儿均通过尸检和产后评估进行随访。结果:43例胎儿经超声检查主观怀疑有小颌畸形。经客观IFA测量,25例IFA为50°。25例IFA 50°,15例正常,3例有其他畸形。在本研究队列中,未发现假阳性结果。四段法诊断PRS的敏感性为92.9%,特异性为100%,阳性预测值为100%,阴性预测值为91.7%。结论:四段式方法在妊娠中期超声检查中对妊娠中期妊娠综合征的评估是非常有效的。结合小颌和光泽度的评估可显著提高产前PRS诊断的准确性。
{"title":"Application of four-section approach for prenatal diagnosis of Pierre robin sequence.","authors":"Xiuling Li, Lingyan Liu, Fang Yan, Xiang Yang, Guanghui Xiu, Xudong Dong","doi":"10.1007/s10396-025-01556-x","DOIUrl":"10.1007/s10396-025-01556-x","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the effectiveness of the four-section approach using two-dimensional sonography in diagnosing Pierre Robin sequence (PRS) during second-trimester screening.</p><p><strong>Methods: </strong>A prospective study was conducted on low-risk pregnant women undergoing routine mid-trimester screening. Cases with suspected micrognathia prenatally were included and examined using the four-section approach. Initially, we measured the inferior facial angle (IFA) for fetuses suspected of having micrognathia. Subsequently, in the oblique coronal section via the oral fissure, we examined the continuity of the hard and soft palate line. Finally, dynamic scanning of both the sagittal and coronal sections of the mandible was performed to confirm whether the echogenic tongue was displaced posteriorly. All fetuses diagnosed with PRS were followed up through autopsy and postnatal evaluation.</p><p><strong>Results: </strong>Forty-three fetuses were initially subjectively suspected of having micrognathia by sonographers. After objective IFA measurement, 25 cases had an IFA < 50°, while 18 had an IFA > 50°. Among the 25 cases with IFA < 50°, we identified 13 cases of PRS with micrognathia, cleft palate (CP), and glossoptosis. However, one case failed to be diagnosed prenatally because it had micrognathia and CP but no glossoptosis. Eleven cases had neither CP nor glossoptosis yet exhibited other malformations. Among the 18 fetuses with IFA > 50°, 15 cases were normal, while three cases had other deformities. In this study cohort, no false-positive results were found. The four-section approach for diagnosing PRS showed a sensitivity of 92.9%, a specificity of 100%, a positive predictive value of 100%, and a negative predictive value of 91.7%.</p><p><strong>Conclusion: </strong>The four-section method proved highly effective in assessing PRS during second-trimester sonographic scans. The combined evaluation of micrognathia and glossoptosis can remarkably enhance the accuracy of prenatal PRS diagnosis.</p>","PeriodicalId":50130,"journal":{"name":"Journal of Medical Ultrasonics","volume":" ","pages":"405-414"},"PeriodicalIF":2.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12634787/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144976919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sonographic evaluation of vascular normalization induced by lenvatinib in a patient with hepatocellular carcinoma.","authors":"Hiroshi Takahashi, Katsutoshi Sugimoto, Naohisa Kamiyama, Tatsuya Kakegawa, Takuya Wada, Hirohito Takeuchi, Takao Itoi","doi":"10.1007/s10396-025-01550-3","DOIUrl":"10.1007/s10396-025-01550-3","url":null,"abstract":"","PeriodicalId":50130,"journal":{"name":"Journal of Medical Ultrasonics","volume":" ","pages":"439-440"},"PeriodicalIF":2.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144052069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-01Epub Date: 2025-08-11DOI: 10.1007/s10396-025-01558-9
Deli Meng, Min Wang
We aimed to compare the outcomes of endobronchial ultrasound-transbronchial needle aspiration (EBUS-TBNA) between elderly and non-elderly patients utilizing a systematic review and meta-analysis. Repositories of PubMed, Embase, Scopus, and Web of Science were searched up to 25 January 2025 for all comparative studies providing data on the adequacy of the sample obtained from the procedure, procedure duration, and complications. Random-effects meta-analysis was conducted. Six studies were eligible. Meta-analysis showed no statistically significant difference in procedure duration, inadequate sampling, and all complications between elderly and non-elderly groups. There was no statistically significant difference between elderly and non-elderly for specific complications like bleeding, cardiovascular events, and hypoxemia. Subgroup analysis based on the definition of elderly did not change the results of inadequate sampling and all complications. Descriptive analysis of the diagnostic accuracy of EBUS-TBNA for malignant lesions showed no difference between the two groups. EBUS-TBNA seems to have similar diagnostic yield and complication rates in the elderly as compared to the non-elderly population. More studies are needed to improve the quality of evidence.
我们旨在通过系统回顾和荟萃分析比较老年和非老年患者的支气管内超声-经支气管针吸(EBUS-TBNA)的结果。检索截至2025年1月25日的PubMed、Embase、Scopus和Web of Science数据库,查找所有提供从手术中获得的样本的充分性、手术持续时间和并发症数据的比较研究。进行随机效应荟萃分析。6项研究符合条件。荟萃分析显示,老年组和非老年组在手术时间、采样不足和所有并发症方面无统计学差异。老年人和非老年人在特定并发症如出血、心血管事件和低氧血症方面没有统计学上的显著差异。基于老年定义的亚组分析没有改变采样不足和所有并发症的结果。描述性分析EBUS-TBNA对恶性病变的诊断准确性显示两组间无差异。与非老年人群相比,EBUS-TBNA在老年人中似乎具有相似的诊断率和并发症发生率。需要更多的研究来提高证据的质量。
{"title":"Outcomes of endobronchial ultrasound-transbronchial needle aspiration in elderly patients: A systematic review and meta-analysis.","authors":"Deli Meng, Min Wang","doi":"10.1007/s10396-025-01558-9","DOIUrl":"10.1007/s10396-025-01558-9","url":null,"abstract":"<p><p>We aimed to compare the outcomes of endobronchial ultrasound-transbronchial needle aspiration (EBUS-TBNA) between elderly and non-elderly patients utilizing a systematic review and meta-analysis. Repositories of PubMed, Embase, Scopus, and Web of Science were searched up to 25 January 2025 for all comparative studies providing data on the adequacy of the sample obtained from the procedure, procedure duration, and complications. Random-effects meta-analysis was conducted. Six studies were eligible. Meta-analysis showed no statistically significant difference in procedure duration, inadequate sampling, and all complications between elderly and non-elderly groups. There was no statistically significant difference between elderly and non-elderly for specific complications like bleeding, cardiovascular events, and hypoxemia. Subgroup analysis based on the definition of elderly did not change the results of inadequate sampling and all complications. Descriptive analysis of the diagnostic accuracy of EBUS-TBNA for malignant lesions showed no difference between the two groups. EBUS-TBNA seems to have similar diagnostic yield and complication rates in the elderly as compared to the non-elderly population. More studies are needed to improve the quality of evidence.</p>","PeriodicalId":50130,"journal":{"name":"Journal of Medical Ultrasonics","volume":" ","pages":"377-385"},"PeriodicalIF":2.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144818062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-01Epub Date: 2025-06-12DOI: 10.1007/s10396-025-01553-0
Yibing Zhao, Rongfang Dong, Xi Chen, Tao Chen
Ultrasound is a good diagnostic technique for musculoskeletal system diseases in children. At present, musculoskeletal ultrasound is widely used in diagnosing soft tissue and joint diseases in pediatric patients, but its application for bone and cartilage diseases is limited. However, ultrasound examination is very important for the diagnosis of bone and cartilage diseases in children. Especially for lesions displaying periosteum, ultrasound has unique advantages, but there are few reports. This article summarized the normal, variant and abnormal ultrasound findings of periosteum on the surface of bone cortex, which could help to diagnose the diseases of children's skeletal system.
{"title":"Ultrasound features of periosteal abnormalities in children.","authors":"Yibing Zhao, Rongfang Dong, Xi Chen, Tao Chen","doi":"10.1007/s10396-025-01553-0","DOIUrl":"10.1007/s10396-025-01553-0","url":null,"abstract":"<p><p>Ultrasound is a good diagnostic technique for musculoskeletal system diseases in children. At present, musculoskeletal ultrasound is widely used in diagnosing soft tissue and joint diseases in pediatric patients, but its application for bone and cartilage diseases is limited. However, ultrasound examination is very important for the diagnosis of bone and cartilage diseases in children. Especially for lesions displaying periosteum, ultrasound has unique advantages, but there are few reports. This article summarized the normal, variant and abnormal ultrasound findings of periosteum on the surface of bone cortex, which could help to diagnose the diseases of children's skeletal system.</p>","PeriodicalId":50130,"journal":{"name":"Journal of Medical Ultrasonics","volume":" ","pages":"365-376"},"PeriodicalIF":2.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144276491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Purpose: This study aimed to elucidate the effectiveness of intestinal ultrasound (IUS) in assessing induction therapy for active ulcerative colitis (UC).
Methods: Thirty-two patients (12 with severe colitis and 20 with moderate colitis) were analyzed. Disease activity was assessed using the Mayo endoscopic score (MES) obtained via colonoscopy. Ultrasound (US) grade and bowel wall thickness (BWT) before induction therapy were compared in terms of MES. Changes in US grade and BWT from pre-treatment to clinical improvement were analyzed at the most inflamed segments, oral side, and anal side.
Results: A correlation coefficient of 0.58 (p < 0.01) indicated a strong correlation between US grade and MES. US grade and BWT decreased at the most inflamed segments, oral side, and anal side for clinical improvement in all cases (p < 0.01, p < 0.01, respectively). However, changes in US grade were significantly greater on the oral side than the most inflamed segments or the anal side (p = 0.008 and p = 0.039, respectively).
Conclusion: IUS is an effective method for assessing the efficacy of induction therapy for active UC. The assessment should be performed at the proximal part of the colon, rather than solely at the site of the most pronounced inflammation.
{"title":"Changes in proximal colon on intestinal ultrasound indicate the efficacy of induction therapy for active ulcerative colitis.","authors":"Koichi Izumikawa, Tomoki Inaba, Eriko Yasutomi, Sakuma Takahashi, Hugh Shunsuke Colvin, Ichiro Sakakihara, Kumiko Yamamoto, Shigetomi Tanaka, Shigenao Ishikawa, Masaki Wato","doi":"10.1007/s10396-025-01554-z","DOIUrl":"10.1007/s10396-025-01554-z","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to elucidate the effectiveness of intestinal ultrasound (IUS) in assessing induction therapy for active ulcerative colitis (UC).</p><p><strong>Methods: </strong>Thirty-two patients (12 with severe colitis and 20 with moderate colitis) were analyzed. Disease activity was assessed using the Mayo endoscopic score (MES) obtained via colonoscopy. Ultrasound (US) grade and bowel wall thickness (BWT) before induction therapy were compared in terms of MES. Changes in US grade and BWT from pre-treatment to clinical improvement were analyzed at the most inflamed segments, oral side, and anal side.</p><p><strong>Results: </strong>A correlation coefficient of 0.58 (p < 0.01) indicated a strong correlation between US grade and MES. US grade and BWT decreased at the most inflamed segments, oral side, and anal side for clinical improvement in all cases (p < 0.01, p < 0.01, respectively). However, changes in US grade were significantly greater on the oral side than the most inflamed segments or the anal side (p = 0.008 and p = 0.039, respectively).</p><p><strong>Conclusion: </strong>IUS is an effective method for assessing the efficacy of induction therapy for active UC. The assessment should be performed at the proximal part of the colon, rather than solely at the site of the most pronounced inflammation.</p>","PeriodicalId":50130,"journal":{"name":"Journal of Medical Ultrasonics","volume":" ","pages":"387-394"},"PeriodicalIF":2.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144303457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Purpose: This study aimed to investigate muscle atrophy in critically ill patients using ultrasonography. We compared the rectus femoris (a major muscle of the lower limbs) with the sternocleidomastoid (an accessory respiratory muscle).
Methods: Thirty-four patients hospitalized at the Critical Care Medical Center of Kindai University Hospital between January 2022 and March 2023 were enrolled. Muscle dysfunction was measured based on the thickness and cross-sectional area of the rectus femoris and sternocleidomastoid using ultrasonography. These values were evaluated every alternate day for 13 days after admission or until discharge, whichever occurred first. Factors that correlated with percentage changes in sternocleidomastoid thickness were also analyzed.
Results: The mean age of the patients was 67.3 ± 15.3 years, and 20 (59%) were men. Seven patients (21%) were admitted for trauma, and 27 (79%) for medical or other non-trauma-related emergency conditions. The rectus femoris thickness and cross-sectional area significantly decreased after day 7 (P < 0.05). There was no significant change in sternocleidomastoid thickness. However, it negatively correlated with the length of hospitalization and duration of mechanical ventilation use (r = - 0.38, P < 0.05; r = - 0.64, P < 0.05, respectively).
Conclusion: Although rectus femoris thickness decreased significantly, changes in sternocleidomastoid thickness may be related to the use of mechanical ventilation.
{"title":"Differences in muscle atrophy between the lower limbs and the accessory respiratory muscles in critically ill patients.","authors":"Ryuji Sugiya, Shinichi Arizono, Yuji Higashimoto, Masashi Shiraishi, Hiroki Mizusawa, Kazunari Sunagawa, Hironori Shigeoka, Yasushi Uchiyama, Jan Bakker, Koichiro Shinozaki","doi":"10.1007/s10396-025-01568-7","DOIUrl":"10.1007/s10396-025-01568-7","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to investigate muscle atrophy in critically ill patients using ultrasonography. We compared the rectus femoris (a major muscle of the lower limbs) with the sternocleidomastoid (an accessory respiratory muscle).</p><p><strong>Methods: </strong>Thirty-four patients hospitalized at the Critical Care Medical Center of Kindai University Hospital between January 2022 and March 2023 were enrolled. Muscle dysfunction was measured based on the thickness and cross-sectional area of the rectus femoris and sternocleidomastoid using ultrasonography. These values were evaluated every alternate day for 13 days after admission or until discharge, whichever occurred first. Factors that correlated with percentage changes in sternocleidomastoid thickness were also analyzed.</p><p><strong>Results: </strong>The mean age of the patients was 67.3 ± 15.3 years, and 20 (59%) were men. Seven patients (21%) were admitted for trauma, and 27 (79%) for medical or other non-trauma-related emergency conditions. The rectus femoris thickness and cross-sectional area significantly decreased after day 7 (P < 0.05). There was no significant change in sternocleidomastoid thickness. However, it negatively correlated with the length of hospitalization and duration of mechanical ventilation use (r = - 0.38, P < 0.05; r = - 0.64, P < 0.05, respectively).</p><p><strong>Conclusion: </strong>Although rectus femoris thickness decreased significantly, changes in sternocleidomastoid thickness may be related to the use of mechanical ventilation.</p>","PeriodicalId":50130,"journal":{"name":"Journal of Medical Ultrasonics","volume":" ","pages":"425-433"},"PeriodicalIF":2.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145006777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}