Godfrey M. Shayo, Elianaso Elimbinzi, Godlisten N. Shao
Water safety concerns are increasing tremendously as a result of the rising population and environmental pollution. As a result, viable water treatment approaches need to be designed to meet the water consumption demands of the population, particularly in developing countries. The recent technological advances in water treatment and purification are well articulated in this review. The efficiency of the materials used for purification and their affordability for people living in rural and remote settlements in various parts of the world have been discussed. Water treatment techniques prior to the rapid advancement of science and technology included a variety of strategies such as coagulation/flocculation, filtration, disinfection, flotation and pH correction. The use of nanotechnology in water treatment and purification has modernized the purification process. Therefore, efficient removal of microbes such as bacteria and viruses are exquisitely accomplished. These technologies may include membrane filtration, ultraviolet irradiation, advanced oxidation ion-exchange and biological filtration technologies. Thus, nanotechnology allows for the fabrication of less expensive systems, allowing even low-income people to benefit from it. Most developing countries find these technologies particularly valuable because access to clean and safe water for drinking and residential needs is critical. This is because access to municipal water supplies is also difficult.
{"title":"Water-based technologies for improving water quality at the point of use: A review","authors":"Godfrey M. Shayo, Elianaso Elimbinzi, Godlisten N. Shao","doi":"10.1002/wnan.1940","DOIUrl":"https://doi.org/10.1002/wnan.1940","url":null,"abstract":"Water safety concerns are increasing tremendously as a result of the rising population and environmental pollution. As a result, viable water treatment approaches need to be designed to meet the water consumption demands of the population, particularly in developing countries. The recent technological advances in water treatment and purification are well articulated in this review. The efficiency of the materials used for purification and their affordability for people living in rural and remote settlements in various parts of the world have been discussed. Water treatment techniques prior to the rapid advancement of science and technology included a variety of strategies such as coagulation/flocculation, filtration, disinfection, flotation and pH correction. The use of nanotechnology in water treatment and purification has modernized the purification process. Therefore, efficient removal of microbes such as bacteria and viruses are exquisitely accomplished. These technologies may include membrane filtration, ultraviolet irradiation, advanced oxidation ion-exchange and biological filtration technologies. Thus, nanotechnology allows for the fabrication of less expensive systems, allowing even low-income people to benefit from it. Most developing countries find these technologies particularly valuable because access to clean and safe water for drinking and residential needs is critical. This is because access to municipal water supplies is also difficult.","PeriodicalId":501345,"journal":{"name":"WIREs Nanomedicine and Nanobiotechnology","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139582559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The oxygen level in the tumor is a critical marker that determines response to different treatments. Cancerous cells can adapt to hypoxia and low pH conditions within the tumor microenvironment (TME) to regulate tumor metabolism, proliferation, and promote tumor metastasis as well as angiogenesis, consequently leading to treatment failure and recurrence. In recent years, widespread attempts have been made to overcome tumor hypoxia through different methods, such as hyperbaric oxygen therapy (HBOT), hyperthermia, O2 carriers, artificial hemoglobin, oxygen generator hydrogels, and peroxide materials. While oxygen is found to be an essential agent to improve the treatment response of photodynamic therapy (PDT) and other cancer treatment modalities, the development of hypoxia within the tumor is highly associated with PDT failure. Recently, the use of nanoparticles has been a hot topic for researchers and exploited to overcome hypoxia through Oxygen-generating hydrogels, O2 nanocarriers, and O2-generating nanoparticles. This review aimed to discuss the role of nanotechnology in tumor oxygenation and highlight the challenges, prospective, and recent advances in this area to improve PDT outcomes.
{"title":"Nanotechnology-mediated photodynamic therapy: Focus on overcoming tumor hypoxia","authors":"Kave Moloudi, Heidi Abrahamse, Blassan P. George","doi":"10.1002/wnan.1937","DOIUrl":"https://doi.org/10.1002/wnan.1937","url":null,"abstract":"The oxygen level in the tumor is a critical marker that determines response to different treatments. Cancerous cells can adapt to hypoxia and low pH conditions within the tumor microenvironment (TME) to regulate tumor metabolism, proliferation, and promote tumor metastasis as well as angiogenesis, consequently leading to treatment failure and recurrence. In recent years, widespread attempts have been made to overcome tumor hypoxia through different methods, such as hyperbaric oxygen therapy (HBOT), hyperthermia, O<sub>2</sub> carriers, artificial hemoglobin, oxygen generator hydrogels, and peroxide materials. While oxygen is found to be an essential agent to improve the treatment response of photodynamic therapy (PDT) and other cancer treatment modalities, the development of hypoxia within the tumor is highly associated with PDT failure. Recently, the use of nanoparticles has been a hot topic for researchers and exploited to overcome hypoxia through Oxygen-generating hydrogels, O<sub>2</sub> nanocarriers, and O<sub>2</sub>-generating nanoparticles. This review aimed to discuss the role of nanotechnology in tumor oxygenation and highlight the challenges, prospective, and recent advances in this area to improve PDT outcomes.","PeriodicalId":501345,"journal":{"name":"WIREs Nanomedicine and Nanobiotechnology","volume":"68 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138560473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The cover image is based on the Editorial Persian perspectives: Special issue on nanomedicine and nanobiotechnology in Iran by Jeff W. M. Bulte and Ali Shakeri-Zadeh https://doi.org/10.1002/wnan.1931. Image Credit: Miranda Ansari (Graphic MiM).
封面图片基于Jeff W. M. Bulte和Ali Shakeri-Zadeh的《波斯社论视角:伊朗纳米医学和纳米生物技术特刊》https://doi.org/10.1002/wnan.1931。图片来源:Miranda Ansari (Graphic MiM)。
{"title":"Cover Image, Volume 15, Issue 6","authors":"","doi":"10.1002/wnan.1936","DOIUrl":"https://doi.org/10.1002/wnan.1936","url":null,"abstract":"The cover image is based on the Editorial <i>Persian perspectives: Special issue on nanomedicine and nanobiotechnology in Iran</i> by Jeff W. M. Bulte and Ali Shakeri-Zadeh https://doi.org/10.1002/wnan.1931. Image Credit: Miranda Ansari (Graphic MiM).","PeriodicalId":501345,"journal":{"name":"WIREs Nanomedicine and Nanobiotechnology","volume":"210 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138523333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The cover image is based on the Advanced Review A narrative review on the role of carbon nanoparticles in oncology by Meghan M. Watt et al., https://doi.org/10.1002/wnan.1845.
封面图片来自于《Advanced Review》，这是一篇关于碳纳米颗粒在肿瘤学中的作用的叙述性综述，作者是Meghan M. Watt等人，https://doi.org/10.1002/wnan.1845。
{"title":"Cover Image, Volume 15, Issue 2","authors":"","doi":"10.1002/wnan.1883","DOIUrl":"https://doi.org/10.1002/wnan.1883","url":null,"abstract":"The cover image is based on the Advanced Review <i>A narrative review on the role of carbon nanoparticles in oncology</i> by Meghan M. Watt et al., https://doi.org/10.1002/wnan.1845.","PeriodicalId":501345,"journal":{"name":"WIREs Nanomedicine and Nanobiotechnology","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138522009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The cover image is based on the Advanced Review Electrospun fibers as carriers for topical drug delivery and release in skin bandages and patches for atopic dermatitis treatment by Zuzanna J. Krysiak and Urszula Stachewicz https://doi.org/10.1002/wnan.1829.
封面图片是基于《先进评论》，由Zuzanna J. Krysiak和Urszula Stachewicz研究，电纺丝纤维作为局部药物递送和释放的载体，用于皮肤绷带和贴片治疗特应性皮炎https://doi.org/10.1002/wnan.1829。
{"title":"Cover Image, Volume 15, Issue 1","authors":"","doi":"10.1002/wnan.1878","DOIUrl":"https://doi.org/10.1002/wnan.1878","url":null,"abstract":"The cover image is based on the Advanced Review <i>Electrospun fibers as carriers for topical drug delivery and release in skin bandages and patches for atopic dermatitis treatment</i> by Zuzanna J. Krysiak and Urszula Stachewicz https://doi.org/10.1002/wnan.1829.","PeriodicalId":501345,"journal":{"name":"WIREs Nanomedicine and Nanobiotechnology","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138522010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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