Pub Date : 2024-04-04DOI: 10.1097/ju.0000000000003928
Surena F Matin, Mehrad Adibi, Amishi Y Shah, Omar Alhalabi, Paul Corn, Charles Guo, Rhenita Amirtharaj, Lianchun Xiao, Suzanne Lange, Dzifa Y Duose, Shufang Wang, Sumanta Pal, Matthew T Campbell
We initiated a biomarker-informed preoperative study of infigratinib, a Fibroblast Growth Factor Receptor (FGFR) inhibitor, in patients with localized upper tract urothelial carcinoma (UTUC), a population with high unmet needs and tumor with a high frequency of FGFR3 alterations.
{"title":"Phase 1b Trial Evaluating Tolerability and Activity of Targeted FGFR Inhibition in Localized Upper Tract Urothelial Carcinoma.","authors":"Surena F Matin, Mehrad Adibi, Amishi Y Shah, Omar Alhalabi, Paul Corn, Charles Guo, Rhenita Amirtharaj, Lianchun Xiao, Suzanne Lange, Dzifa Y Duose, Shufang Wang, Sumanta Pal, Matthew T Campbell","doi":"10.1097/ju.0000000000003928","DOIUrl":"https://doi.org/10.1097/ju.0000000000003928","url":null,"abstract":"We initiated a biomarker-informed preoperative study of infigratinib, a Fibroblast Growth Factor Receptor (FGFR) inhibitor, in patients with localized upper tract urothelial carcinoma (UTUC), a population with high unmet needs and tumor with a high frequency of FGFR3 alterations.","PeriodicalId":501636,"journal":{"name":"The Journal of Urology","volume":"117 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140349006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-04DOI: 10.1097/ju.0000000000003929
Rachel A Moses, Alexandra E Hunter, Eileen R Brandes, Ziyin Zhang, Judy R Rees, Janet L Peacock, William Bihrle, Kinjal Sethuraman, Lindell K Weaver, Jay C Buckey
To determine changes in patient reported hematuria and urinary symptoms after hyperbaric oxygen (HBO2) treatment for radiation cystitis (RC).
目的：确定高压氧（HBO2）治疗放射性膀胱炎（RC）后患者报告的血尿和泌尿系统症状的变化。
{"title":"Patient Reported Outcome Measures Following Hyperbaric Oxygen Therapy for Radiation Cystitis: Early Results From the Multicenter Registry for Hyperbaric Oxygen Therapy.","authors":"Rachel A Moses, Alexandra E Hunter, Eileen R Brandes, Ziyin Zhang, Judy R Rees, Janet L Peacock, William Bihrle, Kinjal Sethuraman, Lindell K Weaver, Jay C Buckey","doi":"10.1097/ju.0000000000003929","DOIUrl":"https://doi.org/10.1097/ju.0000000000003929","url":null,"abstract":"To determine changes in patient reported hematuria and urinary symptoms after hyperbaric oxygen (HBO<sub>2</sub>) treatment for radiation cystitis (RC).","PeriodicalId":501636,"journal":{"name":"The Journal of Urology","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140349012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-03DOI: 10.1097/JU.0000000000003926
R. Szabo
{"title":"Letter: Complications Following Transrectal and Transperineal Prostate Biopsy: Results of the ProBE-PC Randomized Clinical Trial.","authors":"R. Szabo","doi":"10.1097/JU.0000000000003926","DOIUrl":"https://doi.org/10.1097/JU.0000000000003926","url":null,"abstract":"","PeriodicalId":501636,"journal":{"name":"The Journal of Urology","volume":"57 2","pages":"101097JU0000000000003926"},"PeriodicalIF":0.0,"publicationDate":"2024-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140748676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-21DOI: 10.1097/ju.0000000000003884
Nahid Punjani, Jessica A Marinaro, Caroline Kang, Jonathan Gal, Brady Rippon, Rohan Jotwani, Roniel Weinberg, Peter N Schlegel
To assess the safety and efficacy of gabapentin in reducing post-operative pain among patients undergoing scrotal surgery for male infertility by conducting a randomized, double-blind, placebo-controlled trial.
{"title":"Gabapentin for Post-operative Pain Control and Opioid Reduction in Scrotal Surgery: A Randomized Controlled Clinical Trial.","authors":"Nahid Punjani, Jessica A Marinaro, Caroline Kang, Jonathan Gal, Brady Rippon, Rohan Jotwani, Roniel Weinberg, Peter N Schlegel","doi":"10.1097/ju.0000000000003884","DOIUrl":"https://doi.org/10.1097/ju.0000000000003884","url":null,"abstract":"To assess the safety and efficacy of gabapentin in reducing post-operative pain among patients undergoing scrotal surgery for male infertility by conducting a randomized, double-blind, placebo-controlled trial.","PeriodicalId":501636,"journal":{"name":"The Journal of Urology","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139917407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-18DOI: 10.1097/ju.0000000000003826
Carlos Ignacio Calvo, Kai Fender, Nathan Hoy, Keith Rourke
There is a paucity of reported long-term outcomes after contemporary urethroplasty. Our objective is to determine the long-term success of modern urethroplasty and identify factors associated with stricture recurrence in this context.
{"title":"Affirming Long-Term Outcomes after Contemporary Urethroplasty: The Adverse Impact of Increasing Stricture Length, Lichen Sclerosus, Radiation and Infectious Strictures.","authors":"Carlos Ignacio Calvo, Kai Fender, Nathan Hoy, Keith Rourke","doi":"10.1097/ju.0000000000003826","DOIUrl":"https://doi.org/10.1097/ju.0000000000003826","url":null,"abstract":"There is a paucity of reported long-term outcomes after contemporary urethroplasty. Our objective is to determine the long-term success of modern urethroplasty and identify factors associated with stricture recurrence in this context.","PeriodicalId":501636,"journal":{"name":"The Journal of Urology","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138740030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-18DOI: 10.1097/ju.0000000000003825
Michael E Rezaee, Maximilian Pallauf, Sean A Fletcher, Misop Han, Christian P Pavlovich, Chien-Kuang Cornelia Ding, Jonathan I Epstein, Mohamad E Allaf, Bruce J Trock, Nirmish Singla
To examine the association of extraprostatic extension (EPE) with biochemical recurrence (BCR) separately in men with grade group 1 (GG1) and GG2 prostate cancer (PCa) treated with radical prostatectomy.
{"title":"Risk of Biochemical Recurrence in Patients with Grade Group 1 Prostate Cancer with Extraprostatic Extension Treated with Radical Prostatectomy.","authors":"Michael E Rezaee, Maximilian Pallauf, Sean A Fletcher, Misop Han, Christian P Pavlovich, Chien-Kuang Cornelia Ding, Jonathan I Epstein, Mohamad E Allaf, Bruce J Trock, Nirmish Singla","doi":"10.1097/ju.0000000000003825","DOIUrl":"https://doi.org/10.1097/ju.0000000000003825","url":null,"abstract":"To examine the association of extraprostatic extension (EPE) with biochemical recurrence (BCR) separately in men with grade group 1 (GG1) and GG2 prostate cancer (PCa) treated with radical prostatectomy.","PeriodicalId":501636,"journal":{"name":"The Journal of Urology","volume":"35 10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138740149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-18DOI: 10.1097/ju.0000000000003820
Emily S Barker, Kimberley Chiu, Victoria L Brown, Haidy Morsy, Lauren H Yaeger, Arya Catna, Ratna Pakpahan, Robert Moldwin, Barbara Shorter, Jerry L Lowder, H Henry Lai, Siobhan Sutcliffe
To systematically review and summarize the peer-reviewed literature on urologic chronic pelvic pain syndrome (UCPPS) flares, including their terminology, manifestation, perceived triggers, management and prevention strategies, impact on quality of life, and insights into pathophysiologic mechanisms, as a foundation for future empirical research.
{"title":"Urologic Chronic Pelvic Pain Syndrome Flares: A Comprehensive, Systematic Review and Meta-Analysis of the Peer-Reviewed Flare Literature.","authors":"Emily S Barker, Kimberley Chiu, Victoria L Brown, Haidy Morsy, Lauren H Yaeger, Arya Catna, Ratna Pakpahan, Robert Moldwin, Barbara Shorter, Jerry L Lowder, H Henry Lai, Siobhan Sutcliffe","doi":"10.1097/ju.0000000000003820","DOIUrl":"https://doi.org/10.1097/ju.0000000000003820","url":null,"abstract":"To systematically review and summarize the peer-reviewed literature on urologic chronic pelvic pain syndrome (UCPPS) flares, including their terminology, manifestation, perceived triggers, management and prevention strategies, impact on quality of life, and insights into pathophysiologic mechanisms, as a foundation for future empirical research<b>.</b>","PeriodicalId":501636,"journal":{"name":"The Journal of Urology","volume":"81 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138740226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-15DOI: 10.1097/ju.0000000000003799
Naeem Bhojani, Daniel Wollin, Marawan M El Tayeb, Kymora B Scotland, John Knoedler, Karen L Stern, David-Dan Nguyen, Marcelino Rivera, Michael S Borofsky, Noah Canvasser, Seth K Bechis, Ryan S Hsi
Flank pain associated with stone disease is typically caused by a stone that obstructs urine flow. However, it is plausible that nonobstructing kidney stones may still cause pain. We performed a multicenter, observational trial to evaluate whether treatment of small nonobstructing calyceal stones improves pain and kidney stone-specific health-related quality of life.
{"title":"Prospective Multicenter Evaluation of Pain Before and After Removal of Nonobstructing Renal Calculi: A CoRE Initiative.","authors":"Naeem Bhojani, Daniel Wollin, Marawan M El Tayeb, Kymora B Scotland, John Knoedler, Karen L Stern, David-Dan Nguyen, Marcelino Rivera, Michael S Borofsky, Noah Canvasser, Seth K Bechis, Ryan S Hsi","doi":"10.1097/ju.0000000000003799","DOIUrl":"https://doi.org/10.1097/ju.0000000000003799","url":null,"abstract":"Flank pain associated with stone disease is typically caused by a stone that obstructs urine flow. However, it is plausible that nonobstructing kidney stones may still cause pain. We performed a multicenter, observational trial to evaluate whether treatment of small nonobstructing calyceal stones improves pain and kidney stone-specific health-related quality of life.","PeriodicalId":501636,"journal":{"name":"The Journal of Urology","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138657437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-15DOI: 10.1097/ju.0000000000003811
M P Mannas, F M Deng, A Ion-Margineanu, D Jones, D Hoskoppal, J Melamed, S Pastore, C Freudiger, D A Orringer, S S Taneja
Stimulated Raman histology is an innovative technology that generates real-time, high-resolution microscopic images of unprocessed tissue, significantly reducing prostate biopsy interpretation time. This study aims to evaluate the ability for an artificial intelligence convolutional neural network to interpretate prostate biopsy histologic images created with stimulated Raman histology.
{"title":"Stimulated Raman Histology Interpretation by Artificial Intelligence Provides Near-Real-Time Pathologic Feedback for Unprocessed Prostate Biopsies.","authors":"M P Mannas, F M Deng, A Ion-Margineanu, D Jones, D Hoskoppal, J Melamed, S Pastore, C Freudiger, D A Orringer, S S Taneja","doi":"10.1097/ju.0000000000003811","DOIUrl":"https://doi.org/10.1097/ju.0000000000003811","url":null,"abstract":"Stimulated Raman histology is an innovative technology that generates real-time, high-resolution microscopic images of unprocessed tissue, significantly reducing prostate biopsy interpretation time. This study aims to evaluate the ability for an artificial intelligence convolutional neural network to interpretate prostate biopsy histologic images created with stimulated Raman histology.","PeriodicalId":501636,"journal":{"name":"The Journal of Urology","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138657493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-08DOI: 10.1097/ju.0000000000003740
Reece M Anderson, Andriana Peña, Trevor Magee, Del Perkins, Bradley S Johnson, Rodney H Breau, Matt Vassar
Harms are often overlooked, but important, outcomes of randomized controlled trial reporting. Our goal was to determine if harms reporting has improved in high-impact urology journals.
{"title":"Reporting of Harms in Randomized Controlled Trials Published in Urology Journals: An Updated Analysis.","authors":"Reece M Anderson, Andriana Peña, Trevor Magee, Del Perkins, Bradley S Johnson, Rodney H Breau, Matt Vassar","doi":"10.1097/ju.0000000000003740","DOIUrl":"https://doi.org/10.1097/ju.0000000000003740","url":null,"abstract":"Harms are often overlooked, but important, outcomes of randomized controlled trial reporting. Our goal was to determine if harms reporting has improved in high-impact urology journals.","PeriodicalId":501636,"journal":{"name":"The Journal of Urology","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138559383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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