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Microbiological substantiation of the effectiveness of quercitin and its combination with ethylmethylhydroxypyridine succinate in the complex treatment of odontogenic phlegmon and maxillofacial abscesses 从微生物学角度证实槲皮素及其与琥珀酸羟甲基吡啶乙酯复方制剂在治疗牙源性痰盂和颌面部脓肿中的有效性
Pub Date : 2024-01-19 DOI: 10.3389/froh.2024.1338258
Kateryna Lokes, A. Kiptilyi, Margaryta Skikevych, Dmytro V. Steblovskyi, Vitaliy Lychman, Serhii Bilokon, David Avetikov
Odontogenic infections can become life-threatening. The aim of the study was to determine the effectiveness of quercitin and its combination with ethylmethylhydroxypyridine succinate in the complex treatment of odontogenic infections by assessing the microbial population of the infection site.The cross-sectional study included 75 patients. Purulent exudate was collected from the infection site. The number of colony-forming units was counted using the standard plate method.The microbiological examination of purulent exudate obtained from the patients revealed the general prevalence of Gram-positive cocci. On the seventh day of treatment, the total number of microorganisms in the purulent exudate of patients in group I, whose treatment included a combination of the standard protocol with quercitin, significantly decreased compared to the first day of the same group. The results of treatment of patients in group II, which included the standard protocol in combination with quercitin and 2-ethyl-6-methyl-3-hydroxypyridine succinate, demonstrate a significant decrease in the total number of bacteria in the infection focus on the fifth day of treatment compared to this indicator of the group at the beginning of the study.When quercitin was used as part of complex treatment, the total treatment period was reduced by 1.4 days. However, the combined use of quercitin and ethylmethylhydroxypyridine succinate against the background of standard treatment of patients with odontogenic infection contributed to a reduction in hospital stay by 2 days.
牙源性感染可危及生命。该研究旨在通过评估感染部位的微生物群,确定槲皮素及其与琥珀酸乙羟吡啶复方制剂在牙源性感染复合治疗中的有效性。横断面研究包括 75 名患者,从感染部位收集脓性渗出物。对患者脓性渗出物的微生物学检查显示,革兰氏阳性球菌普遍流行。在治疗的第七天,I 组患者化脓性渗出物中的微生物总数与第一天相比明显减少,I 组患者的治疗包括标准方案与槲皮素的联合治疗。第二组患者的治疗结果表明,与研究开始时该组患者的这一指标相比,治疗第五天感染灶中的细菌总数明显减少,该组患者的治疗包括标准方案与槲皮素和 2-乙基-6-甲基-3-羟基吡啶琥珀酸盐的联合治疗。然而,在对牙源性感染患者进行标准治疗的背景下,联合使用槲皮素和琥珀酸乙羟吡啶可使住院时间缩短 2 天。
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引用次数: 0
Grand challenges and future oral epidemiology research 重大挑战和未来的口腔流行病学研究
Pub Date : 2024-01-10 DOI: 10.3389/froh.2023.1349252
M. Foláyan, Jacqueline R. Starr
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引用次数: 0
Canadian dentists’ awareness and views on early childhood caries and its prevention and management 加拿大牙医对儿童早期龋齿及其预防和管理的认识和看法
Pub Date : 2024-01-08 DOI: 10.3389/froh.2023.1268350
Joshua Levesque, Suhird Ghotra, B. Mittermuller, D. Demaré, Victor H. K. Lee, Vivianne Cruz de Jesus, O. Olatosi, Hamideh Alai-Towfigh, R. Schroth
The Canadian Dental Association (CDA) recommends children visit a dentist within 6 months of the eruption of their first tooth or by 12 months of age. The aim of this study was to investigate Canadian dentists’ awareness and views on early childhood caries (ECC) and its prevention and management.This study analyzed a subset of questions relating to dentists’ knowledge of ECC and prevention strategies, from a national survey of general and pediatric dentists, commissioned by the CDA in 2013. Analyses included descriptive, bivariate, and multivariate analyses. A p-value of ≤0.05 was considered significant.Three thousand two hundred thirty-two out of 14,747 dentists responded (response rate of 21.9%), with 95.1% having heard of ECC. Overall, 60.9% of respondents reported that they were comfortable providing treatment to children with ECC. Significant differences were found between the number of years in practice and whether dentists were or were not comfortable providing prevention (19.5 ± 12.6 years vs. 25.4 ± 12.1 years; p < 0.001) or treatment for patients with ECC (19.1 ± 12.7 years vs. 22.5 ± 12.3 years; p < 0.001). Pediatric dentists (OR = 6.92; 95% CI: 2.57, 18.61), female dentists (OR = 1.13; 95% CI: 1.03, 1.24), dentists practicing in smaller urban areas (OR = 1.17; 95% CI: 1.07, 1.28), and dentists who were aware of the CDA's position on ECC (OR = 1.26; 95% CI: 1.13, 1.41) were more likely to be comfortable providing treatment for children with ECC.While the majority of Canadian dentists have sufficient knowledge of ECC, not all are comfortable providing oral health care services to children at a young age. It is encouraging however, that most dentists are wanting additional oral health resources designed for education on ECC prevention for parents of young children.
加拿大牙科协会(CDA)建议儿童在长出第一颗牙后 6 个月内或 12 个月大时去看牙医。本研究旨在调查加拿大牙医对儿童早期龋齿(ECC)及其预防和管理的认识和看法。本研究分析了由加拿大牙医协会于2013年委托进行的一项全国普通牙医和儿童牙医调查中有关牙医对ECC的认识和预防策略的问题子集。分析包括描述性分析、双变量分析和多变量分析。14747名牙医中有3232人做出了回复(回复率为21.9%),其中95.1%的人听说过ECC。总体而言,60.9%的受访者表示他们愿意为患有 ECC 的儿童提供治疗。从业年限与牙医是否乐于为 ECC 患者提供预防(19.5 ± 12.6 年 vs. 25.4 ± 12.1 年;p < 0.001)或治疗(19.1 ± 12.7 年 vs. 22.5 ± 12.3 年;p < 0.001)之间存在显著差异。儿童牙医(OR = 6.92; 95% CI: 2.57, 18.61)、女性牙医(OR = 1.13; 95% CI: 1.03, 1.24)、在较小城市地区执业的牙医(OR = 1.17; 95% CI: 1.07, 1.28)以及了解 CDA 对 ECC 立场的牙医(OR = 1.虽然大多数加拿大牙医对 ECC 有足够的了解,但并非所有牙医都愿意为年幼儿童提供口腔保健服务。不过,令人鼓舞的是,大多数牙医都希望获得更多的口腔保健资源,以便为幼儿家长提供预防幼儿口腔疾病的教育。
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引用次数: 0
An investigation of data from the first year of the interim Canada Dental Benefit for children <12 years of age 针对 12 岁以下儿童的加拿大临时牙科福利第一年的数据调查
Pub Date : 2024-01-08 DOI: 10.3389/froh.2023.1328491
R. Schroth, Vivianne Cruz de Jesus, Anil Menon, O. Olatosi, Victor H. K. Lee, Kathy Yerex, K. Hai-Santiago, D. Demaré
In 2022, the federal government announced a commitment of $5.3B to provide dental care for the uninsured, beginning with children <12 years of age. Now referred to as the Interim Canada Dental Benefit (CDB), the program targets those <12 years of age from families with annual incomes <$90,000 without private dental insurance. The purpose of this study was to review federal data from the Government of Canada on public uptake and applications made to the Canada Revenue Agency (CRA) during the first year of the Interim CDB.Data for the first year of the Interim CDB (up to June 30, 2023) were accessed from the Government of Canada Open Data Portal through Open Government Licence—Canada. Rates of children receiving the Interim CDB per 1,000 were calculated by dividing the number of beneficiaries by the total number of children 0–11 years by province or territory, available from Statistics Canada for the year 2021.During the first year of the program, a total of 204,270 applications were approved, which were made by 188,510 unique applicants for 321,000 children <12 years of age. Over $197M was distributed by the CRA. Overall, the national rate for receiving the Interim CDB was 67.8/1,000 children. Ontario (82.5/1,000), Manitoba (77.1/1,000), Nova Scotia (73.4/1,000), and Saskatchewan (72.3%), all had rates of children with the Interim CDB above the national rate.Data from the first year of the Interim CDB suggests that this federal funding is increasing access to care for children <12 years by addressing the affordability of dental care. Governments and the oral health professions need to address other dimensions of access to care including accessibility, availability, accommodation, awareness, and acceptability of oral health care.
2022 年,联邦政府宣布投入 53 亿加元为无保险者提供牙科保健,首先从 12 岁以下儿童开始。该计划现在被称为 "加拿大临时牙科福利"(CDB),主要针对年收入低于 9 万加元且没有私人牙科保险的家庭中的 12 岁以下儿童。本研究的目的是审查加拿大政府提供的有关临时 CDB 第一年的公众接受情况和向加拿大税务局(CRA)提出申请的联邦数据。临时 CDB 第一年(截至 2023 年 6 月 30 日)的数据是通过开放政府许可证-加拿大从加拿大政府开放数据门户网站获取的。每 1,000 名儿童中领取临时 CDB 的比率是用受益人数除以各省或地区 0-11 岁儿童总人数计算得出的,该数据可从加拿大统计局获得 2021 年的数据。在该计划实施的第一年,共有 204,270 份申请获得批准,这些申请由 188,510 名独特的申请人提出,涉及 321,000 名年龄小于 12 岁的儿童。CRA 共发放了超过 1.97 亿美元。总体而言,全国接受临时 CDB 的儿童比例为 67.8/1,000。安大略省(82.5/1,000)、马尼托巴省(77.1/1,000)、新斯科舍省(73.4/1,000)和萨斯喀彻温省(72.3%)获得临时 CDB 的儿童比例均高于全国比例。各国政府和口腔卫生专业需要解决获得保健的其他方面问题,包括口腔保健的可获得性、可用性、便利性、认知度和可接受性。
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引用次数: 0
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Frontiers in Oral Health
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