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Relationship between caries indexes and obesity in a sample of Puerto Rican adolescents 波多黎各青少年样本中龋齿指数与肥胖之间的关系
Pub Date : 2024-07-26 DOI: 10.3389/fdmed.2024.1391833
L. M. López del Valle, Mariely Nieves-Plaza, Sona Rivas-Tumanyan, Rosana Hanke-Herrero
Obesity and caries have become increasingly prevalent. As yet, research results on the relationship between obesity and caries in children and adolescents have been inconclusive. This study aimed to evaluate the association between caries and obesity in adolescents.This was a cross-sectional study of a convenience sample of 187 Puerto Rican adolescents aged 13–19 years, attending, among them, five high schools. Each participant received dental exams for caries using the criteria of the International Caries Detection and Assessment System (ICDAS), had his or her body mass index (BMI) determined, and took a 19-item risk-factor questionnaire. The Significant Caries (SiC) index (for DMFT) was calculated to compare obese and healthy adolescents. Statistical analysis was performed using descriptive and inferential statistics.Nearly 60% of the sample population was female, with a mean age of 15.7 (±1.25). The mean BMI percentile was 72.24 (±28.78); 48.66% of the participants had a healthy weight, 19.79% were overweight, and 30.48% were obese. Dental caries was observed in 68% of the participants; the mean caries indexes D3-6MFS was 5.17(±5.92) and mean D3-6MFT 3.59 (±3.97). No significant differences were found between caries indexes and obesity status (P > 0.05). The Median (p25, p75) SiC index among overweight/obese adolescents was 9.5 (7, 12), whereas for healthy weight/underweight participants was 7 (5, 8) (p < 0.005).Based on the limited number of participants, no association was found between dental caries (D3-6MFS and D3-6MFT) and obesity (BMI) among adolescents.
肥胖和龋齿的发病率越来越高。迄今为止,有关儿童和青少年肥胖与龋齿之间关系的研究结果尚无定论。本研究旨在评估青少年龋齿与肥胖之间的关系。这是一项横断面研究,方便抽样调查了 187 名波多黎各青少年,年龄在 13-19 岁之间,其中有五所高中。每位参与者都按照国际龋齿检测和评估系统 (ICDAS) 的标准接受了龋齿检查,确定了体重指数 (BMI),并填写了一份包含 19 个项目的风险因素问卷。通过计算重要龋齿(SiC)指数(针对 DMFT)来比较肥胖青少年和健康青少年。统计分析采用描述性和推论性统计方法。样本中近 60% 为女性,平均年龄为 15.7 岁(±1.25)。平均体重指数百分位数为 72.24(±28.78);48.66% 的参与者体重健康,19.79% 超重,30.48% 肥胖。68%的参与者患有龋齿;龋齿指数 D3-6MFS 平均值为 5.17(±5.92),D3-6MFT 平均值为 3.59(±3.97)。龋齿指数与肥胖状况之间无明显差异(P > 0.05)。超重/肥胖青少年的龋齿指数中位数(p25,p75)为 9.5(7,12),而健康体重/体重不足的青少年的龋齿指数中位数为 7(5,8)(P < 0.005)。
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引用次数: 0
Host modulation therapy in periodontitis, diagnosis and treatment—status update 牙周炎的宿主调节疗法、诊断和治疗--最新进展
Pub Date : 2024-07-16 DOI: 10.3389/fdmed.2024.1423401
L. M. Golub, Hsi-Ming Lee, Joseph Bacigalupo, Ying Gu
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引用次数: 0
2020 Grand challenge revisited: removing silos, advancing research to improve overall health 重温 2020 年的重大挑战:消除孤岛,推进研究,改善整体健康状况
Pub Date : 2024-07-11 DOI: 10.3389/fdmed.2024.1430828
Martha J. Somerman, W. Mouradian, S. Ganesan
This perspective provides strong evidence that the aims set forth when Frontiers in Dental Medicine (FDMED) was launched in 2020, to advance the integration of dental, oral, and craniofacial research with mainstream biomedical practice, underscored the value of interprofessional research collaborations, encouraging studies, publications, and commentaries in this area ripe for continued innovation. The momentum gained toward these aims must continue to inform the public, health care providers, researchers, educators, and policy makers so that they can apply the knowledge gained to improve the overall health needs of all our communities.
这一观点有力地证明了口腔医学前沿(FDMED)于2020年启动时提出的目标,即推进牙科、口腔和颅面研究与主流生物医学实践的结合,强调了跨专业研究合作的价值,鼓励在这一领域开展研究、发表文章和评论,并不断创新。实现这些目标的势头必须继续向公众、医疗保健提供者、研究人员、教育工作者和政策制定者宣传,以便他们能够应用所获得的知识来改善我们所有社区的整体健康需求。
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引用次数: 0
Editorial: Temporomandibular disorder: new directions in research and patient care 社论:颞下颌关节紊乱:研究和患者护理的新方向
Pub Date : 2024-07-10 DOI: 10.3389/fdmed.2024.1452938
John W. Kusiak, Richard Ohrbach, Alexandre Da Silva, Mildred Embree
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引用次数: 0
Novel digital technique for measuring the volumetric healing process of free gingival grafts surrounding dental implants 测量牙种植体周围游离牙龈移植体体积愈合过程的新型数字技术
Pub Date : 2024-07-02 DOI: 10.3389/fdmed.2024.1372312
Cristian Docampo-Vázquez, Teresa Gragera-Alia, Manuel Fernández-Domínguez, Álvaro Zubizarreta-Macho, Juan Manuel Aragoneses-Lamas
The objective of the present study was to analyze and describe a new digital technique for analyzing the volumetric healing process of free gingival grafts in both donor and recipient locations surrounding a dental implant, as well as to compare the reliability of conventional and digital techniques for measuring the width of the free gingival graft in the recipient location throughout the healing process.Ten patients presenting with mucositis linked to a dental implant were included. A preoperative soft tissue width <2 mm, with probing pocket depth <5 mm, edema and inflammation and bleeding on probing was determined A digital impression was taken of both donor and recipient locations using an intraoral scan, generating a Standard Tessellation Language digital file both preoperatively (STL1) and after 1 week (STL2), 1 month (STL3), 3 months (STL4), and 6 months (STL5) of follow-up. Afterwards, the digital files (STL1-STL5) were aligned using a reverse engineering morphometric software, and Student's t-test was used to analyze changes in volume at the donor and recipient locations. Additionally, widths were measured both clinically and digitally so as to compare the reliability of these measurement techniques. The repeatability and reproducibility of both these measurement techniques were also analyzed using Gage R&R statistical analysis.Gage R&R found that total variability of the digital technique was 0.6% (among the measures of each operator) and 7.6% (among operators); as variability was under 10%, the results were repeatable and reproducible. In addition, there were statistically significant differences between donor and recipient locations in healing process volume (mm3) after one week (p = 0.0110), one month (p = 0.0007), three months (p < 0.0001) and six months (p = 0.0004) of follow-up.The digital measurement technique provided accurate, repeatable, and reproducible results when analyzing the volumetric and lineal measures of the healing process in both the donor and recipient locations of a free gingival graft surrounding a dental implant, with significantly higher tissue volume in the recipient location.
本研究的目的是分析和描述一种新的数字化技术,用于分析牙种植体周围供体和受体位置游离龈移植体的体积愈合过程,并比较传统技术和数字化技术在整个愈合过程中测量受体位置游离龈移植体宽度的可靠性。术前软组织宽度小于 2 毫米,探诊袋深度小于 5 毫米,探诊时有水肿、炎症和出血。术前(STL1)和术后 1 周(STL2)、1 个月(STL3)、3 个月(STL4)和 6 个月(STL5)随访后,使用口内扫描对供体和受体位置进行数字化印模,生成标准网格语言数字文件。之后,使用逆向工程形态计量软件对数字文件(STL1-STL5)进行对齐,并使用学生 t 检验分析供体和受体位置的体积变化。此外,为了比较这两种测量技术的可靠性,还通过临床和数字技术测量了宽度。Gage R&R 统计分析发现,数字技术的总变异率为 0.6%(每个操作者的测量值之间)和 7.6%(操作者之间);由于变异率低于 10%,因此结果具有可重复性和再现性。此外,在一周(p = 0.0110)、一个月(p = 0.0007)、三个月(p < 0.0001)和六个月(p = 0.0004)的随访后,供体和受体位置之间的愈合过程体积(mm3)差异具有统计学意义。在分析牙种植体周围游离龈移植供体和受体位置愈合过程的体积和线性测量结果时,数字测量技术提供了准确、可重复和可再现的结果,其中受体位置的组织体积明显更高。
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引用次数: 0
Periodontal ageing and its management via pharmacological glucose modulation 牙周老化及其通过药理葡萄糖调节进行的管理
Pub Date : 2024-07-01 DOI: 10.3389/fdmed.2024.1415960
Vitor C. M. Neves, Viktor Savchenko, James Daly, Paul Sharpe
Periodontal disease (PD), a widespread non-communicable disease, affects over 90% of the global population with no known cure. Current management strategies focus on stabilization of disease progression, which is successfully achieved to a limited extent. Yet the never-ending battle of bacteria and the gingiva involves a complex interplay between genetic, microbial and environmental factors, demanding innovative approaches to improve prevention and stabilisation of this disease. Glucose is the body's source of energy and research has shown that dysregulation of the glucose metabolism impacts PD establishment and progression, as well as impact development of systemic non communicable diseases. Metformin, a drug known for its efficacy in diabetes treatment via controlling glucose metabolism, also demonstrated cardioprotective effects, increased longevity, and anti-inflammatory properties. Metformin has been used in gel format in clinical trials for PD non-surgical treatment, however, its systemic use in normoglycemic individuals with PD is less explored. A recent study presented compelling evidence of Metformin's preventive potential, impacting PD and markers of systemic health involved in metabolic health liked to improvement of lifespan. Therefore, this review discusses the aspects of ageing as a concept in the periodontium and the potential benefits of modulating glucose metabolism through Metformin to prevent PD, indirectly preventing systemic conditions involved in multi-morbidity, addressing a critical gap in current management. It also examines the choice between implementation of behaviour change and/or medication as strategy to add to current oral hygiene strategies. Finally, it discusses the ethical implications of prescribing systemic medication in dentistry.
牙周病(PD)是一种广泛存在的非传染性疾病,影响着全球 90% 以上的人口,目前尚无根治方法。目前的治疗策略主要是稳定疾病的进展,这在一定程度上取得了成功。然而,细菌与牙龈之间无休止的斗争涉及遗传、微生物和环境因素之间复杂的相互作用,因此需要创新的方法来改善这种疾病的预防和稳定。葡萄糖是人体的能量来源,研究表明,葡萄糖代谢失调会影响帕金森病的发生和发展,并影响全身性非传染性疾病的发展。二甲双胍是一种通过控制葡萄糖代谢治疗糖尿病的药物,它还具有保护心脏、延年益寿和抗炎的作用。在临床试验中,二甲双胍以凝胶的形式被用于帕金森病的非手术治疗,然而,对其在血糖正常的帕金森病患者中的全身应用却探索较少。最近的一项研究提出了令人信服的证据,证明二甲双胍具有预防潜力,可影响肢端麻痹症和涉及代谢健康的全身健康指标,从而改善患者的寿命。因此,本综述讨论了老龄化作为牙周概念的各个方面,以及通过二甲双胍调节葡萄糖代谢来预防帕金森病的潜在益处,从而间接预防涉及多种疾病的系统性状况,解决当前管理中的一个关键缺口。报告还探讨了在当前口腔卫生策略的基础上,如何选择实施行为改变和/或药物治疗的策略。最后,它还讨论了牙科处方全身用药的伦理意义。
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引用次数: 0
Students’ perceptions of endodontic typodont teeth with simulated canals printed from novel materials 学生对使用新型材料印制的模拟牙管进行牙髓分型的看法
Pub Date : 2024-06-14 DOI: 10.3389/fdmed.2024.1373922
A. J. Cresswell-Boyes, Graham Roy Davis, Aylin Baysan
This study aimed to investigate students' perceptions of the use of 3D-printed typodonts by implementing a questionnaire and evaluating the students' comparisons between extracted, commercial and 3D-printed teeth.Ethical approval was obtained (QMER20.586/2021) and questionnaire feedback was collected anonymously using an online survey. A total of 143 fourth- and fifth-year dental students were approached to participate during pre-clinical courses focussing on root canal therapy. The tooth design was based on micro-CT data of an extracted maxillary central incisor and 3D-printed with haptically-similar materials produced in previous work. The questionnaire comprised 11 Likert-scale questions, four open-ended questions, two “yes” or “no” questions and three closed-ended questions.Eighty questionnaires were returned. Overall, the feedback was favourable towards the 3D-printed typodonts compared to the commercial teeth. The biggest difference in responses was in Question 6 related to the realism of drilling the enamel when comparing 3D-printed teeth with commercial ones. Statistical analysis showed a significant difference (p < 0.05); the fourth-year's response on average, was 2.95 (±0.73) an “agree” rating, whereas the fifth-year's response was 3.98 (±0.82) with “neither agree or disagree”.Within the limitations of this study, the 3D-printed typodonts were rated high in comparison to the commercial teeth in terms of overall operative experiences.
本研究旨在通过实施问卷调查和评估学生对拔牙、商业牙和 3D 打印牙的比较,调查学生对使用 3D 打印牙的看法。研究获得了伦理批准(QMER20.586/2021),并通过在线调查匿名收集问卷反馈。在以根管治疗为重点的临床前课程中,共接触了 143 名四年级和五年级的牙科学生。牙齿设计基于拔出的上颌中切牙的显微 CT 数据,并使用以前工作中生产的触觉类似材料进行 3D 打印。问卷包括 11 个李克特量表问题、4 个开放式问题、2 个 "是 "或 "否 "问题和 3 个封闭式问题。总体而言,与商业牙齿相比,3D 打印的排牙得到了好评。回答中最大的差异出现在第 6 个问题上,即在比较 3D 打印牙和商用牙时,钻珐琅质的逼真度。统计分析表明差异很大(p < 0.05);四年级学生的平均回答为 2.95(±0.73)分,"同意 "分,而五年级学生的回答为 3.98(±0.82)分,"既不同意也不不反对"。
{"title":"Students’ perceptions of endodontic typodont teeth with simulated canals printed from novel materials","authors":"A. J. Cresswell-Boyes, Graham Roy Davis, Aylin Baysan","doi":"10.3389/fdmed.2024.1373922","DOIUrl":"https://doi.org/10.3389/fdmed.2024.1373922","url":null,"abstract":"This study aimed to investigate students' perceptions of the use of 3D-printed typodonts by implementing a questionnaire and evaluating the students' comparisons between extracted, commercial and 3D-printed teeth.Ethical approval was obtained (QMER20.586/2021) and questionnaire feedback was collected anonymously using an online survey. A total of 143 fourth- and fifth-year dental students were approached to participate during pre-clinical courses focussing on root canal therapy. The tooth design was based on micro-CT data of an extracted maxillary central incisor and 3D-printed with haptically-similar materials produced in previous work. The questionnaire comprised 11 Likert-scale questions, four open-ended questions, two “yes” or “no” questions and three closed-ended questions.Eighty questionnaires were returned. Overall, the feedback was favourable towards the 3D-printed typodonts compared to the commercial teeth. The biggest difference in responses was in Question 6 related to the realism of drilling the enamel when comparing 3D-printed teeth with commercial ones. Statistical analysis showed a significant difference (p < 0.05); the fourth-year's response on average, was 2.95 (±0.73) an “agree” rating, whereas the fifth-year's response was 3.98 (±0.82) with “neither agree or disagree”.Within the limitations of this study, the 3D-printed typodonts were rated high in comparison to the commercial teeth in terms of overall operative experiences.","PeriodicalId":502488,"journal":{"name":"Frontiers in Dental Medicine","volume":"47 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141338512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Editorial: Salivary biomarkers for oral and systemic diseases 社论:口腔和全身疾病的唾液生物标志物
Pub Date : 2024-06-12 DOI: 10.3389/fdmed.2024.1429305
Mario Taba, Melissa M. Grant
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引用次数: 0
Application of non-destructive testing methods for assessing fracture resistance in dental ceramics: the sound harvesting test 应用非破坏性测试方法评估牙科陶瓷的抗断裂性:声音采集测试
Pub Date : 2024-06-06 DOI: 10.3389/fdmed.2024.1409150
Camille Haddad, Jean Gebran, Amine El Zoghbi
Evaluating the fracture resistance of dental ceramics such as monolithic zirconia crowns is crucial for assessing their durability. Conventional destructive laboratory tests often fail to accurately evaluate the timing and failing crack formation of these brittle materials. Non-destructive testing methods, such as acoustic emission testing (AET), offers an alternative by providing valuable data on material properties without causing damage to the samples.The in vitro study aimed to evaluate the sensitivity of a sound harvesting modified acoustic emission testing by comparing the fracture resistance of posterior monolithic zirconia crowns (MZCs) measured via the modified set up with that of a conventional fracture toughness test.A modified acoustic emission set up, the sound harvesting test (SHT), featuring a condenser microphone, an amplifier, a custom audio chipset and a cut-off switch integrated into a universal testing machine, was compared to a conventional fracture toughness test to measure fracture loads on 50 posterior monolithic zirconia crowns divided in two groups.The sound harvesting test recorded a mean fracture load of 1,108.99 N, significantly less than the 1,292.52 N measured with the conventional test, indicating a more sensitive detection of fractures. Statistically significant differences (p < 0.05) were observed between the two groups.Despite its limitations, the study suggests considering sound harvesting testing as an potential alternative for fracture load testing of dental brittle materials due to its ability to identify failures at lower loads enhancing therefore a more accurate evaluation of the behavior of dental materials. However, further testing on a broader range of dental materials is warranted to improve result accuracy and applicability.
评估牙科陶瓷(如整体氧化锆牙冠)的抗断裂性对于评估其耐久性至关重要。传统的破坏性实验室测试往往无法准确评估这些脆性材料形成裂纹的时间和失败情况。声发射测试(AET)等非破坏性测试方法提供了一种替代方法,它能在不对样品造成损坏的情况下提供有价值的材料特性数据。这项体外研究旨在通过比较通过改良装置测量的后部整体氧化锆牙冠(MZC)的抗断裂性与传统的断裂韧性测试,评估声收集改良声发射测试的灵敏度。改进的声发射装置--声音采集测试(SHT)集成了一个电容式麦克风、一个放大器、一个定制音频芯片组和一个截止开关,与传统的断裂韧性测试进行了比较,测量了分为两组的50个后部整体氧化锆冠的断裂载荷。尽管有其局限性,但该研究建议考虑将声音采集测试作为牙科脆性材料断裂载荷测试的潜在替代方法,因为它能识别较低载荷下的失效,从而更准确地评估牙科材料的行为。不过,还需要对更多牙科材料进行进一步测试,以提高结果的准确性和适用性。
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引用次数: 0
The impact of Filifactor alocis on the severity of periodontitis among diabetic and non-diabetic patients: a narrative review Filifactor alocis 对糖尿病和非糖尿病患者牙周炎严重程度的影响:叙述性综述
Pub Date : 2024-05-22 DOI: 10.3389/fdmed.2024.1408839
Shumani Charlotte Manenzhe, Sandra Koutras, N. Zwane, Aubrey Isaac Masilana, S. Shangase
The extensive studies on Filifactor alocis (Fa) show a positive association with periodontitis, demonstrating elevated Fa levels compared to traditional periodontal pathogens in severe disease. Periodontitis is a chronic multifactorial disease induced by a dysbiotic microbiota in a susceptible host whilst diabetes is an established risk factor for periodontitis. Diabetes has been shown to alter the subgingival microbiota into distinct microbial communities which favours the shift towards disease. It is these very distinct subgingival microbiota that are believed to contribute to the high prevalence and severity of periodontitis in diabetic patients. This dysbiotic microbiota constitute traditional periodontal pathogens which include among others the red complex triad (Porphyromonas gingivalis, Treponema denticola, Tannerella forsythia), Aggregatibacter actinomycetemcomitans, the orange complex (Fusobacterium nucleatum, Prevotella intermedia etc.) and other emerging pathogens such as Fa that were previously unrecognised as role players in the pathogenesis of periodontitis. Fa is an asaccharolytic anaerobic gram-positive rod (AAGPR) currently considered to be one of the potential drivers of periodontitis progression and worsening through its unique virulence characteristics. Various mechanisms through which Fa contributes to the pathogenesis and severity of periodontitis have been reported. The mechanisms involved in the bidirectional relationship between periodontitis and diabetes are continuously being explored in order to enhance individualised preventative and management approaches in affected patients. This review aims to report on this emerging periodontal pathogen and its capacity to influence dysbiosis within a complex subgingival microbial community; including its potential role in the bidirectional relationship between diabetes and periodontitis. This review will highlight Fa as a potential prognostic indicator for disease worsening, which will help improve management protocols for periodontitis and diabetes.
有关 Filifactor alocis(Fa)的大量研究表明,Fa 与牙周炎有积极的联系,与传统的牙周病病原体相比,Fa 在严重疾病中的含量更高。牙周炎是一种慢性多因素疾病,由易感宿主体内微生物群失调诱发,而糖尿病是牙周炎的既定风险因素。研究表明,糖尿病会改变龈下微生物群,使其形成不同的微生物群落,从而有利于疾病的发生。据信,正是这些截然不同的龈下微生物群导致了糖尿病患者牙周炎的高发病率和严重程度。这种菌群失调的微生物群构成了传统的牙周病病原体,其中包括红色复合三联菌(牙龈卟啉单胞菌、牙龈特雷波氏菌、连翘泰纳菌)、放线菌属(Aggregatibacter actinomycetemcomitans)、橙色复合菌(核分枝杆菌、中间前驱菌等)以及其他新出现的病原体,如以前未被认识到在牙周炎发病机制中起作用的 Fa。Fa是一种溶糖性厌氧革兰阳性杆菌(AAGPR),由于其独特的毒力特征,目前被认为是牙周炎进展和恶化的潜在驱动因素之一。据报道,Fa 对牙周炎的发病机制和严重程度有多种影响。人们正在不断探索牙周炎与糖尿病之间双向关系的相关机制,以加强对受影响患者的个性化预防和管理方法。本综述旨在报告这种新出现的牙周病原体及其在复杂的龈下微生物群落中影响菌群失调的能力,包括其在糖尿病和牙周炎之间双向关系中的潜在作用。本综述将强调 Fa 是疾病恶化的潜在预后指标,这将有助于改善牙周炎和糖尿病的管理方案。
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引用次数: 0
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Frontiers in Dental Medicine
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