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Diabetic foot ulcers: “Just chop it off”? 糖尿病足溃疡:“把它切掉”?
1区 医学 Q1 Medicine Pub Date : 2016-06-01 DOI: 10.1302/2048-0105.53.360435
M. Raglan, B. Scammell
Diabetes is increasingly common, and is associated with significant patient morbidity, mortality and high socioeconomic costs (Table I). Due to the increasing prevalence of diabetes, almost all clinicians will treat patients who suffer from it, or will treat a direct complication of diabetes. One of the most serious complications affecting orthopaedic surgeons is the diabetic foot ulcer (DFU). The aim of this review is to update clinicians on the optimal management of the DFU.View this table:Table I. Diabetes-related statistics in the UKDiabetes is a metabolic disease characterised by hyperglycaemia as a result of defects in insulin secretion or action. In the long-term this leads to damage and dysfunction of organs, specifically the eyes, kidneys, heart, nerves and blood vessels.4 A break in the skin on the foot in the presence of diabetes is known as a diabetic foot ulcer (DFU), and is the leading cause of hospitalisation in patients with diabetes (Fig. 1).5,6Fig. 1 Necrotic diabetic foot ulcer of calcaneum.There are multiple risk factors for the development of a DFU (Table II).5 The most common reasons are related to neuropathy, vasculopathy or a combination of both.7⇓-9 The vast majority of DFU seen in clinics or presenting as emergencies have combined pathology, and only 10% of DFU are due to isolated vasculopathy or peripheral vascular disease (PVD).10View this table:Table II. Risk factors for the development of diabetic foot ulcers5Diabetes is thought to cause damage to the vasa nervorum resulting in an ischaemic insult and a progressive irreversible sensory, motor and autonomic neuropathy. Most presentations of sensory neuropathy are insidious until the onset of complications. The sensory deficit usually occurs below the knee, is denser distally and is bilateral. Sensory deficit results in numbness of the feet with burning, pain or paraesthesia being …
糖尿病越来越普遍,并与显著的患者发病率、死亡率和高社会经济成本相关(表1)。由于糖尿病患病率的增加,几乎所有的临床医生都会治疗患有糖尿病的患者,或治疗糖尿病的直接并发症。影响骨科手术最严重的并发症之一是糖尿病足溃疡(DFU)。本综述的目的是更新临床医生对DFU的最佳管理。表1 .英国糖尿病相关统计数据糖尿病是一种代谢性疾病,其特征是由于胰岛素分泌或作用缺陷导致高血糖。从长远来看,这会导致器官的损伤和功能障碍,特别是眼睛、肾脏、心脏、神经和血管糖尿病患者足部皮肤的破裂被称为糖尿病足溃疡(DFU),是糖尿病患者住院的主要原因(图1)。1糖尿病足跟骨坏死性溃疡。发生DFU有多种危险因素(表2)最常见的原因与神经病变、血管病变或两者的结合有关。绝大多数出现在诊所或急诊的DFU有合并病理,只有10%的DFU是由孤立性血管病变或周围血管疾病(PVD)引起的。查看该表:表二。糖尿病足溃疡发生的危险因素5糖尿病被认为会引起血管神经损伤,导致缺血性损伤和进行性不可逆的感觉、运动和自主神经病变。大多数感觉神经病变的表现是隐匿的,直到出现并发症。感觉缺陷通常发生在膝盖以下,远端更密集,是双侧的。感觉缺陷导致足部麻木,伴有灼烧、疼痛或感觉异常。
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引用次数: 1
The demise of reading: a problem reflected in open access journals? 阅读的消亡:开放获取期刊反映的问题?
1区 医学 Q1 Medicine Pub Date : 2016-06-01 DOI: 10.1302/2048-0105.53.360447
B. Ollivere
Right at the birth of orthopaedic surgery, innovations and new treatments were communicated through letters to societies and in treatises, and rather long textbooks describing experiences of treatments. In fact, the oldest known records of orthopaedic treatments described in the Edwin Smith papyrus from Ancient Egypt are true to this formula of simple series of descriptive cases, a method also used by the fathers of orthopaedic surgery in their own treatises in the 19th century. Academic medical writing, and specifically orthopaedic writing, became more formalised with the advent of scientific societies which soon started circulating newsletters that rapidly became journals with the addition of peer review, …
就在整形外科诞生之初,创新和新的治疗方法通过写信给社会和论文,以及相当长的教科书来描述治疗经验。事实上,古埃及埃德温·史密斯(Edwin Smith)的莎草纸上所记载的最古老的骨科治疗记录,与这种简单的一系列描述性病例的公式是一致的,这种方法也被整形外科之父们在他们自己的论文中使用。学术医学写作,特别是骨科写作,随着科学协会的出现而变得更加正式,科学协会很快开始传播通讯,这些通讯很快成为了同行评议的期刊,……
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引用次数: 0
Consent: Where are we in 2016? 同意:2016年我们在哪里?
1区 医学 Q1 Medicine Pub Date : 2016-06-01 DOI: 10.1302/2048-0105.53.360434
P. Worlock
In 2015, the Supreme Court gave their decision on a case involving the issue of informed consent for an obstetric procedure.1 That judgement (referred to hereafter as ‘Montgomery’) has implications for all doctors practising within the United Kingdom.The claimant was a small, diabetic woman with a large foetus. The risk of shoulder dystocia was estimated to be between 9% and 10%, but the mother was not informed of this because her consultant considered the risk of a ‘grave problem’ for the baby to be “very small” (in the event of shoulder dystocia occurring, there was a 0.2% chance of brachial plexus injury and a 0.1% chance of prolonged hypoxia). The option of planned caesarean section (CS) was not discussed with the claimant, and induction was planned for 39 weeks. During delivery, there was occlusion of the umbilical cord resulting in a hypoxic brain injury.Subsequently, the mother claimed that she should have been warned of the risk of shoulder dystocia and the potentially catastrophic consequences, and of the alternative of planned CS, in which case she would have opted for CS. At both the initial trial and on appeal, the defendant’s experts stated that the “risk of grave problems was very small”, but also that “if such women were warned, most would opt for CS”. Both courts concluded that to not warn the patient was accepted as proper by a responsible body of medical opinion.The Supreme Court accepted that the consultant’s decision accorded with a reasonable body of opinion, but that patients have rights and are not passive recipients of the care of the medical profession. A person is entitled to decide which, if any, of the available forms of treatment to undergo. The Supreme Court accepted that, if appropriately warned, the claimant would not have agreed …
2015年,最高法院就一宗涉及产科手术知情同意问题的案件作出了裁决该判决(以下简称“蒙哥马利”)对所有在英国执业的医生都有影响。索赔人是一个身材矮小的糖尿病妇女,胎儿很大。肩部难产的风险估计在9%到10%之间,但母亲没有被告知这一点,因为她的顾问认为婴儿出现“严重问题”的风险“非常小”(如果发生肩部难产,臂丛损伤的可能性为0.2%,长时间缺氧的可能性为0.1%)。没有与索赔人讨论计划剖宫产(CS)的选择,计划引产39周。在分娩过程中,脐带闭塞导致缺氧脑损伤。随后,这位母亲声称,她应该被告知肩难产的风险和潜在的灾难性后果,以及计划剖腹产的选择,如果是这样的话,她会选择剖腹产。在初审和上诉中,被告的专家都表示“严重问题的风险非常小”,但也表示“如果这些妇女得到警告,大多数人会选择CS”。两个法院的结论都是,不警告病人被负责任的医学意见机构认为是适当的。最高法院认为,顾问的决定符合合理的意见,但病人有权利,不是被动接受医疗专业护理的人。一个人有权决定接受哪一种治疗,如果有的话。最高法院承认,如果得到适当的警告,索赔人是不会同意的。
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引用次数: 0
Work life balance and unusual activities in the Arctic 工作与生活的平衡以及在北极的不寻常活动
1区 医学 Q1 Medicine Pub Date : 2016-04-01 DOI: 10.1302/2048-0105.52.360431
B. Ollivere
I find myself stood on the start line for the Beyond the Ultimate Ice Ultra marathon in Northern Lapland, well into the Sami territories of the European Arctic, contemplating just over four days of running over 240 km of mountains and frozen lakes using ancient migration trails. With home, work and worries far away I always find time for my annual pilgrimage to run an ultramarathon in a far flung area of the planet. Racing with a good friend for five days across frozen lakes, over mountains, braving snow shoes and temperatures as low as -25 might not be everyone’s cup of tea but it certainly serves to put life into perspective. This was one of the best ultra races I have had the opportunity to race …
我发现自己站在拉普兰北部的“超越极限冰上超级马拉松”的起跑线上,深入到欧洲北极的萨米人领地,思考着四天多的时间,沿着古老的迁徙路线,跑过240多公里的山脉和冰冻的湖泊。远离了家、工作和烦恼,我总能抽出时间来进行一年一度的朝圣之旅,去地球上遥远的地方跑一场超级马拉松。和一个好朋友在冰封的湖泊、高山上进行五天的比赛,冒着雪地鞋和零下25度的低温进行比赛,这可能不是每个人都喜欢的,但它确实有助于人们对生活的看法。这是我有机会参加的最好的超级比赛之一……
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引用次数: 0
Advancement and acceleration in medico-legal practice: what’s it all about? 医学法律实践的进步和加速:这一切都是关于什么?
1区 医学 Q1 Medicine Pub Date : 2016-04-01 DOI: 10.1302/2048-0105.52.360419
M. Foy
In 2013 we ran a session entitled, ‘Pain, Percentages, Advancement/Acceleration and other nebulous concepts in medico-legal practice’ at the BOA Annual Congress in Birmingham. The session was vastly oversubscribed with people sitting/standing in the aisles and over 50 attendees locked out by the fire safety officer. Speakers included a barrister, psychiatrist, pain specialist and an orthopaedic surgeon. The level of interest in this session emphasised the topicality of the issues under review. As I continue to read medical reports in personal injury claims where it is argued that such and such an injury has caused the onset of certain symptoms and disability to be advanced/accelerated by a certain period, I thought that it might be worth re-visiting the subject to consider its validity in these cases.What do we mean by advancement or acceleration of symptoms? Effectively we are arguing that given the nature of the underlying condition (most commonly back pain), and our understanding of the epidemiology and pathophysiology of that condition, the injury or incident in question has brought forward what would invariably have happened in any event by a certain period of time. Clearly if a pedestrian is walking along the pavement and is struck by a car, it would be ridiculous to argue that this insult had brought forward the tibial fracture by a certain period. However, in a condition as common as back pain where most of the patients we see in clinical practice develop symptoms during the activities of daily living, rather than after a specific injury, it is frequently argued that such an injury or incident has triggered the onset of symptoms which would probably have come on at a later date in any event.Why do we introduce the concept? The simple answer is that we are trying to help the legal …
2013年,我们在伯明翰举行的BOA年度大会上举办了一场题为“医学法律实践中的疼痛、百分比、进步/加速和其他模糊概念”的会议。会议座无虚席,过道里坐着或站着的人太多了,50多名与会者被消防安全官员锁在了门外。演讲者包括律师、精神病学家、疼痛专家和整形外科医生。对本届会议的关注程度突出了审查中的问题的时效性。当我继续阅读人身伤害索赔中的医疗报告时,有人认为这样或那样的伤害导致某些症状和残疾的发作提前/加速了一段时间,我认为可能值得重新审视这个问题,以考虑其在这些案件中的有效性。什么是症状的恶化或加速?实际上,我们认为,鉴于潜在疾病的性质(最常见的是背部疼痛),以及我们对该疾病的流行病学和病理生理学的理解,有问题的伤害或事件提前了在特定时期内任何事件都会发生的事情。很明显,如果一个行人在人行道上行走时被汽车撞了,那么认为这种侮辱使胫骨骨折提前了一定时间是荒谬的。然而,在像背痛这样常见的情况下,我们在临床实践中看到的大多数患者在日常生活活动中出现症状,而不是在特定的伤害之后,人们经常认为这种伤害或事件触发了症状的发作,而这些症状在任何情况下都可能在晚些时候出现。我们为什么要引入这个概念?简单的回答是,我们正在努力帮助法律……
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引用次数: 0
Extremity soft tissue sarcomas: what’s hot and what’s not 四肢软组织肉瘤:什么是热的,什么不是
1区 医学 Q1 Medicine Pub Date : 2016-04-01 DOI: 10.1302/2048-0105.52.360427
M. Patel, N. Eastley, R. Ashford
This paper aims to provide evidence-based guidance for the general orthopaedic surgeon faced with the presentation of a potential soft tissue sarcoma in an extremity.
本文旨在为普通骨科医生面对潜在的肢体软组织肉瘤的表现提供循证指导。
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引用次数: 0
The lost art of conservative management of paediatric fractures 儿童骨折保守治疗失传的艺术
1区 医学 Q1 Medicine Pub Date : 2016-02-01 DOI: 10.1302/2048-0105.51.360403
D. Bryson, F. Shivji, K. Price, D. Lawniczak, J. Chell, J. Hunter
The orthopaedic surgeon practising general trauma will invariably encounter fractures in children. Mercer Rang points out in the opening chapter of his textbook, “children are not just small adults”.1 The paediatric skeleton is more forgiving, demonstrates greater rapidity of healing and has an unrivalled capacity to remodel. Greater angulation, translation, and shortening can be accepted and reliably expected to remodel without clinical, functional or radiological shortcomings. Despite the fact that the outcomes following paediatric fractures are predictable and the healing potential offers considerable latitude for restoration of normality, there has been a global paradoxical shift from conservative treatment to early fracture fixation. This has perhaps been driven by the desire for immediate correction of clinical deformities or by financial incentives to minimise hospital costs accrued with prolonged admissions during periods of immobilisation. This review examines the evidence and indications for conservative treatment, and describes our preferences for the management of some commonly encountered paediatric fractures.The ability of the paediatric skeleton to remodel lies at the heart of non-operative management. Semantically, this process is called modeling; remodeling being the constant homeostatic cycling of calcium and phosphate from bone stores. Everyone understands remodeling so we use it now even though it’s wrong! It is the process by which angulation and translation are corrected to restore acceptable alignment. The potential for remodeling is influenced by a number of factors:
骨科医生从事一般创伤将不可避免地遇到儿童骨折。默瑟·朗在他的教科书的第一章中指出:“孩子不仅仅是小大人。儿童骨骼更宽容,愈合速度更快,具有无与伦比的重塑能力。更大的成角、平移和缩短可以被接受,并且可靠地期望在没有临床、功能或放射学缺陷的情况下进行重塑。尽管事实上,儿童骨折后的结果是可预测的,愈合潜力为恢复正常提供了相当大的空间,但从保守治疗到早期骨折固定的全球矛盾转变。这可能是由于希望立即矫正临床畸形,或者是出于财政激励,以尽量减少因固定期间长期住院而产生的医院费用。这篇综述检查了保守治疗的证据和适应症,并描述了我们对一些常见的儿科骨折治疗的偏好。儿童骨骼的重塑能力是非手术治疗的核心。从语义上讲,这个过程称为建模;骨重塑是指骨储存中钙和磷酸盐的恒定稳态循环。每个人都了解重塑,所以我们现在使用它,即使它是错误的!矫正成角和平移以恢复可接受的对准的过程。骨重塑的可能性受到以下几个因素的影响:
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引用次数: 9
Health economic quality of life the bane of genuine outcomes 健康经济生活质量是真正成果的祸根
1区 医学 Q1 Medicine Pub Date : 2016-02-01 DOI: 10.1302/2048-0105.44.360418
B. Ollivere
As Douglas Adams famously said, the answer to life, the universe and everything is “42”. (Question of course as yet unknown). I was taught as a trainee and a young academic that the perennial problem in conducting research is asking the right question – a point Adams makes very eloquently. If you don’t ask the correct question you clearly will not get a reasonable answer – “garbage in – garbage out”. Over the last few years the quality of orthopaedic research in terms of methodology has skyrocketed. Randomised controlled trials abound and there doesn’t seem to be an edition of 360 that goes by without a number of excellent randomised controlled trials to comment upon.Controversially I have become however increasingly concerned about the RCT. Whilst methodologically better at addressing biases there is a risk in the orthopaedic community that …
正如道格拉斯·亚当斯的名言,生命、宇宙和一切的答案都是“42”。(当然,这个问题还不清楚)。作为一名实习生和一名年轻的学者,我被教导说,进行研究的长期问题是提出正确的问题——亚当斯非常雄辩地阐述了这一点。如果你不问正确的问题,你显然不会得到一个合理的答案——“垃圾进垃圾出”。在过去的几年里,骨科研究的质量在方法学方面突飞猛进。随机对照试验比比皆是,《360》的每一个版本似乎都有大量优秀的随机对照试验可供评论。然而,有争议的是,我越来越关注随机对照试验。虽然在方法上更好地解决了偏见,但在骨科领域存在风险……
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引用次数: 0
Medico-legal issues in the foot and ankle specialty 脚部和踝关节专业的医学法律问题
1区 医学 Q1 Medicine Pub Date : 2016-02-01 DOI: 10.1302/2048-0105.45.360404
W. Ribbans
Like all subspecialty areas within orthopaedic surgery, foot and ankle work carries risks, complications and the potential for litigation. Certain areas of this work have been highlighted for this article to aid the surgeon in appropriately counselling the patient, and improving understanding of major risk areas and knowledge of the outcomes of injury and surgery.Historically, information on litigation claims has been difficult to acquire because it involves obtaining information from a number of different bodies. There is no mechanism for compulsory reporting of complications, coding accuracy is usually found wanting, and most claims are either dismissed or settled without going to court. However, in 2014, Ring1 provided an analysis of 1214 National Health Service Litigation Authority (NHSLA) claims in England, involving foot and ankle surgery, over 17 years. These represented 12.6% of orthopaedic claims. Thirty-four per cent of claims involved the ankle, with 73% resulting from trauma. Twenty-one per cent involved the first ray, of which 98% involved elective surgery. Nineteen per cent of claims involved diagnostic errors, 19% were for alleged incompetent surgery, and a further 13% for mismanagement. The authors recognised that reducing incorrect, delayed and missed diagnoses was a key area for improvement.#### Medico-legal implications:Nerve injury is a common foot and ankle surgical complication, with the most frequent causes being inadvertent laceration, entrapment under metalwork, contusion/soft-tissue swelling and accidental injury from suture needle placement. This may result in diminished sensation, painful neuroma formation, adverse effects on mobility and problems with footwear. The sural, superficial peroneal, deep peroneal, saphenous and tibial nerves can all be injured.Bai2 reported a …
像所有整形外科的亚专业领域一样,足部和踝关节手术也有风险、并发症和潜在的诉讼。本文强调了这项工作的某些领域,以帮助外科医生对患者进行适当的咨询,并提高对主要风险领域的理解以及对损伤和手术结果的了解。从历史上看,关于诉讼索赔的资料很难获得,因为它涉及从许多不同的机构获得资料。没有强制报告并发症的机制,编码的准确性通常不足,大多数索赔要么被驳回,要么在没有上法庭的情况下得到解决。然而,在2014年,Ring1提供了一份对英格兰国家卫生服务诉讼管理局(NHSLA) 17年来1214起索赔的分析,涉及足部和踝关节手术。这些占矫形外科索赔的12.6%。34%的索赔涉及脚踝,73%的索赔是由外伤引起的。21%的患者接受了第一次透视,其中98%的患者接受了选择性手术。19%的索赔涉及诊断错误,19%涉及所谓的不合格手术,还有13%涉及管理不善。作者认识到,减少不正确、延迟和漏诊是一个需要改进的关键领域。####医学-法律意义:神经损伤是一种常见的足部和踝关节手术并发症,最常见的原因是无意撕裂伤、金属制品夹伤、挫伤/软组织肿胀和缝线针放置的意外损伤。这可能导致感觉减退,神经瘤形成疼痛,对活动能力的不利影响以及鞋类问题。腓肠、腓浅神经、腓深神经、隐神经和胫神经均可损伤。Bai2报告了…
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引用次数: 0
Bears, bells, healthcare and how do we actually get it right first time? 熊、铃铛、医疗保健以及我们如何在第一次就做到正确?
1区 医学 Q1 Medicine Pub Date : 2015-12-01 DOI: 10.1302/2048-0105.44.360401
B. Ollivere
I was recently privileged to sit through a short lecture by Bill Bryson, someone for whom I have had affection for many years. I had been struck by his earnest humour and thoughtful charm the first time I heard him speak at the BOA a few years ago and was excited to be able to hear him again at a much smaller Orthopaedic forum. Mr Bryson gave a thought-provoking talk set off by his usual amusing anecdote about ‘bears and bells’. However, taking the opportunity to converse with the trainees in the auditorium, he went on to give one of the most profound and beautifully-delivered commentaries on what is wrong and right with modern healthcare I have heard in a number of years. Bryson told of the fate of Katz, the other protagonist of A Walk in the Woods which I am sure will be familiar to many. He traced the difficulties experienced by his childhood friend as a result of the development of simple complications from diabetes, which led eventually …
最近,我有幸听了比尔·布莱森(Bill Bryson)的一场简短演讲,我对他有多年的感情。几年前,我第一次在美国骨科协会听到他的演讲时,我就被他诚挚的幽默和深思的魅力所打动,很高兴能在一个规模小得多的骨科论坛上再次听到他的演讲。布赖森先生以他一贯的“熊和铃铛”的趣闻作为开场白,做了一次发人深省的演讲。然而,趁此机会在礼堂里与学员交谈,他继续就现代医疗保健的对错发表了我多年来听到的最深刻、最精彩的评论之一。布莱森讲述了卡茨的命运,卡茨是《林中漫步》的另一个主人公,我相信很多人都对他很熟悉。他追述了他儿时的朋友由于糖尿病引起的简单并发症而经历的困难,这些并发症最终导致了……
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引用次数: 0
期刊
Journal of Bone and Joint Surgery
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