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Gestational Age Is Positively Associated with Retinol and α-Tocopherol in Preterm Infants: The Mediating Role of Birth Weight 早产儿的妊娠年龄与视黄醇和α-生育酚呈正相关:出生体重的中介作用
Pub Date : 2023-12-18 DOI: 10.3390/dietetics2040027
Panos Papandreou, P. Detopoulou, M. Skouroliakou
Oxidative stress is thought to be one of the common mechanisms for several neonatal diseases in premature infants. Moreover, fat-soluble antioxidant vitamins, i.e., retinol and α-tocopherol, have been found to be low in preterm neonates; however, data are limited. The aim of this was to assess the circulating α-tocopherol and retinol concentrations in preterm infants at birth and investigate if they are related to gestational age. Retinol and α-tocopherol were measured on the first day after birth in 30 preterm neonates with HPLC. Means ± SD of serum retinol and α-tocopherol were 392.0 ± 162.9 μg/L and 6.83 ± 3.02 mg/L, respectively. In total, 73% of infants had a very low birth weight (<1500 g) and 23.3% were small for gestational age (SGA). Moreover, 10% of neonates had a retinol deficiency and 20% had an α-tocopherol deficiency. The retinol concentration was lower in SGA infants compared to appropriate for gestational age ones (340.85 ± 75.89 vs. 407.60 ± 179.83 μg/L, correspondingly p = 0.030). Retinol was linearly related to gestational age (Pearson’s rho = 0.84, p < 0.001) but the association did not remain significant after an adjustment for birth weight (partial rho = 0.193, p = 0.316). α-tocopherol was nonlinearly associated with gestational age (Spearman’s rho = 0.470, p = 0.044). The assessment of the vitamin status and potential deficiency in neonates is crucial in order to appropriately support the nutritional needs of newborns.
氧化应激被认为是早产儿多种新生儿疾病的常见机制之一。此外,脂溶性抗氧化维生素(即视黄醇和α-生育酚)在早产新生儿中含量较低,但相关数据有限。本研究旨在评估早产儿出生时循环中的α-生育酚和视黄醇浓度,并研究它们是否与胎龄有关。采用高效液相色谱法测量了 30 名早产新生儿出生后第一天的视黄醇和 α-生育酚含量。血清视黄醇和α-生育酚的平均值(± SD)分别为 392.0 ± 162.9 μg/L 和 6.83 ± 3.02 mg/L。总共有 73% 的婴儿出生体重非常低(小于 1500 克),23.3% 的婴儿为小于胎龄儿(SGA)。此外,10%的新生儿缺乏视黄醇,20%缺乏α-生育酚。与胎龄适宜的婴儿相比,SGA 婴儿的视黄醇浓度较低(340.85 ± 75.89 vs. 407.60 ± 179.83 μg/L,相应的 p = 0.030)。视黄醇与胎龄呈线性关系(Pearson's rho = 0.84,p < 0.001),但在调整出生体重后,这种关系并不显著(部分 rho = 0.193,p = 0.316)。α-生育酚与胎龄呈非线性关系(Spearman's rho = 0.470,p = 0.044)。为了适当满足新生儿的营养需求,评估新生儿的维生素状况和潜在缺乏症至关重要。
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引用次数: 0
Impact of Corn Fiber on the Physicochemical/Technological Properties, Emotions, Purchase Intent and Sensory Characteristics of Gluten Free Bread with Novel Flours 玉米纤维对新型面粉制成的无麸质面包的理化/工艺性能、情感、购买意向和感官特性的影响
Pub Date : 2023-12-12 DOI: 10.3390/dietetics2040026
Ricardo S Aleman, J. A. Fuentes, Ajitesh Yadav, Shirin Kazemzadeh, Franklin Delcarca, M. Sarmientos, Mehrdad Hasani-Azhdari, Ismael Montero-Fernández
Gluten-free products present huge advantages for individuals with gluten intolerance or celiac disease. The most influential strategy to develop a product comparable to wheat-containing gluten products is to promote its nutritional and sensorial attributes. Recently, rice flour and teosinte flour were used to develop gluten-free bread. As a result, this work aimed to compare the physical/technological attributes of bread made with rice flour and teosinte flour with corn fiber fortification and examine consumer acceptance and purchase intent. An extreme vertices mixture design decided that a teosinte flour (43.4%), high protein white rice flour (55%), and high protein brown rice flour (1.6%) ratio of gluten-free flour mixture for bread was best based on the sensory attributes utilized for the desirability function methodology. After optimizing the gluten-free flour mixture, the bread was fortified with corn fiber under 1.7 g and 3.8 g per serving, and it was evaluated to examine its physical/technological attributes, consumer perception, liking, emotions, and purchase intent. Incorporating fiber into gluten-free bread impacted the color and texture, giving lighter and yellower colors with a firmer texture. Likewise, concerning health benefit claims, gluten-free bread with fiber claims only improves the purchase intent and overall liking of bread containing 1.7 g per serving of fiber. The flavor attribute was the main driver for consumers’ purchase decisions. This product could be beneficial for consumers who are seeking fiber in their diet.
无麸质产品为麸质不耐症或乳糜泻患者带来了巨大的好处。要开发出一种可与含小麦麸质产品媲美的产品,最有影响力的策略就是提升其营养和感官属性。最近,大米粉和茶树蛋白粉被用于开发无麸质面包。因此,这项研究旨在比较用大米面粉和添加了玉米纤维的茶新特面粉制作的面包的物理/技术属性,并考察消费者的接受程度和购买意向。根据可取性函数方法中使用的感官属性,通过极顶点混合物设计,确定了茶新特粉(43.4%)、高蛋白白米粉(55%)和高蛋白糙米粉(1.6%)在面包中的无筋面粉混合物比例最佳。在优化无麸质面粉混合物后,面包添加了每份 1.7 克和 3.8 克以下的玉米纤维,并对其物理/技术属性、消费者感知、喜好、情感和购买意向进行了评估。在无麸质面包中加入纤维会影响面包的颜色和质地,使颜色更浅、更黄,质地更坚实。同样,在健康益处声明方面,含有纤维声明的无麸质面包只提高了购买意向和对每份含有 1.7 克纤维的面包的总体喜爱程度。风味属性是消费者做出购买决定的主要驱动因素。这种产品可能对在饮食中寻求纤维的消费者有益。
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